Temat: "topoisomerase iv" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Actions of a Novel Bacterial Topoisomerase Inhibitor against Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enhancement of Double-Stranded DNA Breaks.
Autorzy:: Dauda SE; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Collins JA; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Byl JAW; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Lu Y; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Yalowich JC; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 42310, USA.
Mitton-Fry MJ; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Osheroff N; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Department of Medicine (Hematology/Oncology), Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; VA Tennessee Valley Healthcare System, Nashville, TN 37212, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 28; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Topoisomerase IV*
Neisseria gonorrhoeae*
Humans ; DNA Gyrase/metabolism ; DNA Breaks, Double-Stranded ; Topoisomerase II Inhibitors/pharmacology ; Topoisomerase II Inhibitors/chemistry

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Skocz do pozycji: 2.

Tytuł:: New Potential Pharmacological Targets of Plant-Derived Hydroxyanthraquinones from Rubia spp.
Autorzy:: Alov P; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Al Sharif M; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Najdenski H; The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Pencheva T; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Tsakovska I; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Zaharieva MM; The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Pajeva I; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 May 19; Vol. 27 (10). Date of Electronic Publication: 2022 May 19.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Topoisomerase IV*
Rubia*
Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; DNA Gyrase/chemistry ; Gatifloxacin ; Molecular Docking Simulation ; Polyphenols

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Skocz do pozycji: 3.

Tytuł:: Novel Tetrazole-Based Antimicrobial Agents Targeting Clinical Bacteria Strains: Exploring the Inhibition of Staphylococcus aureus DNA Topoisomerase IV and Gyrase.
Autorzy:: Roszkowski P; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warszawa, Poland.
Szymańska-Majchrzak J; Chair and Department of Biochemistry, Medical University of Warsaw, 02-097 Warszawa, Poland.
Koliński M; Bioinformatics Laboratory, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawinskiego St., 02-106 Warsaw, Poland.
Kmiecik S; Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, 02-089 Warsaw, Poland.
Wrzosek M; Department of Biochemistry and Pharmacogenomics, Faculty of Pharmacy, Medical University of Warsaw, 02-097 Warsaw, Poland.
Struga M; Chair and Department of Biochemistry, Medical University of Warsaw, 02-097 Warszawa, Poland.
Szulczyk D; Chair and Department of Biochemistry, Medical University of Warsaw, 02-097 Warszawa, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 29; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 29.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Bacterial Agents/*pharmacology
DNA Gyrase/*metabolism
DNA Topoisomerase IV/*antagonists & inhibitors
Staphylococcus aureus/*enzymology
Tetrazoles/*pharmacology
Topoisomerase II Inhibitors/*pharmacology
DNA Topoisomerase IV/metabolism ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Proton Magnetic Resonance Spectroscopy ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/isolation & purification

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Skocz do pozycji: 4.

Tytuł:: Biological Effects of Quinolones: A Family of Broad-Spectrum Antimicrobial Agents.
Autorzy:: Millanao AR; Facultad de Ciencias, Instituto de Farmacia, Universidad Austral de Chile, Valdivia 5090000, Chile.
Mora AY; Programa de Doctorado en Bioquímica, Universidad de Chile, Santiago 8380544, Chile.
Villagra NA; Escuela de Tecnología Médica, Universidad Andres Bello, Santiago 8370071, Chile.
Bucarey SA; Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago 8820808, Chile.
Hidalgo AA; Escuela de Química y Farmacia, Universidad Andres Bello, Santiago 8370071, Chile.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Nov 25; Vol. 26 (23). Date of Electronic Publication: 2021 Nov 25.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Anti-Infective Agents/*chemistry
Bacterial Infections/*drug therapy
DNA Gyrase/*genetics
DNA Topoisomerase IV/*genetics
Quinolones/*chemistry
Anti-Infective Agents/therapeutic use ; Bacterial Infections/genetics ; Bacterial Infections/microbiology ; DNA Gyrase/drug effects ; DNA Topoisomerase IV/antagonists & inhibitors ; DNA, Bacterial/biosynthesis ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/genetics ; Gram-Negative Bacteria/pathogenicity ; Gram-Positive Bacteria/drug effects ; Gram-Positive Bacteria/genetics ; Gram-Positive Bacteria/pathogenicity ; Humans ; Quinolones/therapeutic use ; RNA, Bacterial/biosynthesis ; Topoisomerase II Inhibitors/chemistry ; Topoisomerase II Inhibitors/therapeutic use

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Skocz do pozycji: 5.

Tytuł:: Development and radiosterilization of new hydrazono-quinoline hybrids as DNA gyrase and topoisomerase IV inhibitors: Antimicrobial and hemolytic activities against uropathogenic isolates with molecular docking study.
Autorzy:: Ammar YA; Department of Chemistry, Faculty of Science (Boys), Al-Azhar University, Nasr City, Cairo, Egypt.
Micky JA; Department of Chemistry, Faculty of Science (Girls), Al-Azhar University, Nasr City, Cairo, Egypt.
Aboul-Magd DS; Drug Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Egypt.
Abd El-Hafez SMA; Department of Chemistry, Faculty of Science (Girls), Al-Azhar University, Nasr City, Cairo, Egypt.
Hessein SA; Department of Chemistry, Faculty of Science (Girls), Al-Azhar University, Nasr City, Cairo, Egypt.
Ali AM; Department of Chemistry, Faculty of Science (Girls), Al-Azhar University, Nasr City, Cairo, Egypt.
Ragab A; Department of Chemistry, Faculty of Science (Boys), Al-Azhar University, Nasr City, Cairo, Egypt.; Pokaż więcej
Źródło:: Chemical biology & drug design [Chem Biol Drug Des] 2023 Feb; Vol. 101 (2), pp. 245-270. Date of Electronic Publication: 2022 Oct 28.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Gyrase*/metabolism
Anti-Infective Agents*/pharmacology
Molecular Docking Simulation ; DNA Topoisomerase IV/metabolism ; Topoisomerase II Inhibitors/pharmacology ; Topoisomerase II Inhibitors/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Microbial Sensitivity Tests ; Structure-Activity Relationship ; Molecular Structure

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Skocz do pozycji: 6.

Tytuł:: Role of the Water-Metal Ion Bridge in Quinolone Interactions with Escherichia coli Gyrase.
Autorzy:: Carter HE; Biology Department, University of Evansville, Evansville, IN 47722, USA.
Wildman B; Biology Department, University of Evansville, Evansville, IN 47722, USA.
Schwanz HA; Department of Pharmaceutical Sciences and Experimental Therapeutics, University of Iowa, Iowa City, IA 42232, USA.
Kerns RJ; Department of Pharmaceutical Sciences and Experimental Therapeutics, University of Iowa, Iowa City, IA 42232, USA.
Aldred KJ; Biology Department, University of Evansville, Evansville, IN 47722, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 02; Vol. 24 (3). Date of Electronic Publication: 2023 Feb 02.
Typ publikacji:: Journal Article
MeSH Terms:: Quinolones*/pharmacology
Quinolones*/chemistry
DNA Topoisomerase IV/metabolism ; Escherichia coli/metabolism ; Water/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Metals/chemistry ; Fluoroquinolones/pharmacology ; DNA Gyrase ; Topoisomerase II Inhibitors/pharmacology ; Topoisomerase II Inhibitors/chemistry ; DNA Topoisomerases, Type II/metabolism

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Skocz do pozycji: 7.

Tytuł:: Topoisomerase IV tracks behind the replication fork and the SeqA complex during DNA replication in Escherichia coli.
Autorzy:: Helgesen E; Department of Microbiology, Molecular Microbiology, Oslo University Hospital, P.O. Box 4950, 0424, Oslo, Norway. .; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway. .
Sætre F; Department of Microbiology, Molecular Microbiology, Oslo University Hospital, P.O. Box 4950, 0424, Oslo, Norway.; Department of Pathology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Skarstad K; Department of Microbiology, Molecular Microbiology, Oslo University Hospital, P.O. Box 4950, 0424, Oslo, Norway.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jan 12; Vol. 11 (1), pp. 474. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chromosomes, Bacterial/*metabolism
DNA Replication/*physiology
DNA Topoisomerase IV/*metabolism
Escherichia coli/*genetics
Escherichia coli/*metabolism
Bacterial Outer Membrane Proteins/metabolism ; DNA Topoisomerase IV/antagonists & inhibitors ; DNA-Binding Proteins/metabolism ; Escherichia coli Proteins/metabolism ; Topoisomerase II Inhibitors/pharmacology

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Skocz do pozycji: 8.

Tytuł:: A 2.8 Å Structure of Zoliflodacin in a DNA Cleavage Complex with Staphylococcus aureus DNA Gyrase.
Autorzy:: Morgan H; Medicines Discovery Institute, Cardiff University, Cardiff CF10 3AT, UK.
Lipka-Lloyd M; Medicines Discovery Institute, Cardiff University, Cardiff CF10 3AT, UK.
Warren AJ; Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.
Hughes N; Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK.
Holmes J; Inspiralis Limited, Norwich Research Park Innovation Centre, Norwich NR4 7GJ, UK.
Burton NP; Inspiralis Limited, Norwich Research Park Innovation Centre, Norwich NR4 7GJ, UK.
Mahenthiralingam E; Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK.
Bax BD; Medicines Discovery Institute, Cardiff University, Cardiff CF10 3AT, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 13; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:: Journal Article
MeSH Terms:: Quinolones*/pharmacology
Staphylococcal Infections*
Humans ; DNA Gyrase/metabolism ; Staphylococcus aureus/metabolism ; DNA Topoisomerase IV/genetics ; DNA Cleavage ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Fluoroquinolones ; Topoisomerase II Inhibitors/pharmacology ; Bacteria/metabolism ; Microbial Sensitivity Tests ; DNA Topoisomerases, Type II/metabolism

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Skocz do pozycji: 9.

Tytuł:: Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors.
Autorzy:: Hashem HE; Department of Chemistry, Faculty of Women, Ain Shams University, Heliopolis, Cairo 11457, Egypt.
Amr AEE; Drug Exploration & Development Chair (DEDC), Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.; Applied Organic Chemistry Department, National Research Center, Dokki 12622, Cairo, Egypt.
Nossier ES; Pharmaceutical Medicinal Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11754, Egypt.
Elsayed EA; Bioproducts Research Chair, Zoology Department, Faculty of Science, King Saud University, Riyadh 11451, Saudi Arabia.; Chemistry of Natural and Microbial Products Department, National Research Centre, Dokki 12622, Cairo, Egypt.
Azmy EM; Department of Chemistry, Faculty of Women, Ain Shams University, Heliopolis, Cairo 11457, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Jun 15; Vol. 25 (12). Date of Electronic Publication: 2020 Jun 15.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Topoisomerase IV/*antagonists & inhibitors
Thiourea/*pharmacology
Topoisomerase II Inhibitors/*chemistry
Anti-Bacterial Agents/pharmacology ; DNA Gyrase/chemistry ; DNA Topoisomerase IV/chemistry ; Escherichia coli/drug effects ; Escherichia coli/metabolism ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Imidazoles/chemistry ; Imidazoles/pharmacology ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Structure-Activity Relationship ; Thiadiazoles/chemistry ; Thiadiazoles/pharmacology ; Thiourea/analogs & derivatives ; Thiourea/chemistry ; Triazines/chemistry ; Triazines/pharmacology

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Skocz do pozycji: 10.

Tytuł:: Synthesis, Structural Characterization and Biological Activity Evaluation of Novel Cu(II) Complexes with 3-(trifluoromethyl)phenylthiourea Derivatives.
Autorzy:: Drzewiecka-Antonik A; Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, PL-02668 Warsaw, Poland.
Struga M; Chair and Department of Biochemistry, Medical University of Warsaw, Banacha 1, PL-02097 Warsaw, Poland.
Głogowska A; Institute of Tuberculosis and Lung Diseases, Microbiology Department, Plocka 26, PL-01138 Warsaw, Poland.
Augustynowicz-Kopec E; Institute of Tuberculosis and Lung Diseases, Microbiology Department, Plocka 26, PL-01138 Warsaw, Poland.
Dobrzyńska K; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Warsaw Medical University, 3 Oczki Street, PL-02007 Warsaw, Poland.
Chrzanowska A; Chair and Department of Biochemistry, Medical University of Warsaw, Banacha 1, PL-02097 Warsaw, Poland.
Wolska A; Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, PL-02668 Warsaw, Poland.
Rejmak P; Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, PL-02668 Warsaw, Poland.
Klepka MT; Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, PL-02668 Warsaw, Poland.
Wrzosek M; Department of Biochemistry and Pharmacogenomics, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, PL-02097 Warsaw, Poland.
Bielenica A; Chair and Department of Biochemistry, Medical University of Warsaw, Banacha 1, PL-02097 Warsaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Dec 10; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 10.
Typ publikacji:: Journal Article
MeSH Terms:: Phenylthiourea*
Coordination Complexes*/chemistry
Humans ; Anti-Bacterial Agents/chemistry ; Thiourea/pharmacology ; Thiourea/chemistry ; DNA Topoisomerase IV ; DNA Gyrase ; Copper/chemistry

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Skocz do pozycji: 11.

Tytuł:: Emerging quinoline- and quinolone-based antibiotics in the light of epidemics.
Autorzy:: Kaur P; Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
Anuradha; Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
Chandra A; Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
Tanwar T; Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
Sahu SK; Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
Mittal A; Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.; Pokaż więcej
Źródło:: Chemical biology & drug design [Chem Biol Drug Des] 2022 Dec; Vol. 100 (6), pp. 765-785. Date of Electronic Publication: 2022 Feb 16.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19*
Quinolones*/pharmacology
Quinolones*/therapeutic use
Quinolones*/chemistry
Epidemics*
Zika Virus*
Zika Virus Infection*
Humans ; DNA Topoisomerase IV ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use

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Skocz do pozycji: 12.

Tytuł:: Hotspots sequences of gyrA, gyrB, parC, and parE genes encoded for fluoroquinolones resistance from local Salmonella Typhi strains in Jakarta.
Autorzy:: Nathania I; Department of Microbiology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jalan Pluit Raya No. 2, North Jakarta, 14440, Indonesia.
Nainggolan IM; Department of Clinical Pathology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jalan Pluit Raya No. 2, North Jakarta, 14440, Indonesia.; Eijkman Research Center for Molecular Biology, The National Research and Innovation Agency, Jalan Raya Jakarta Bogor No.46, Pakansari, Cibinong, Kabupaten Bogor, Jawa Barat, 16915, Indonesia.
Yasmon A; Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jalan Pegangsaan Timur 16, Jakarta, 10320, Indonesia.
Nusatia ACM; St. Carolus Hospital, Jalan Salemba Raya No. 41, Jakarta, 10440, Indonesia.
Tjoa E; Department of Microbiology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jalan Pluit Raya No. 2, North Jakarta, 14440, Indonesia.
Gunardi WD; Department of Microbiology, Krida Wacana Christian University, Jalan Arjuna Utara No. 6, Jakarta, 11510, Indonesia.
Moehario LH; Department of Microbiology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jalan Pluit Raya No. 2, North Jakarta, 14440, Indonesia. .; Pokaż więcej
Źródło:: BMC microbiology [BMC Microbiol] 2022 Oct 18; Vol. 22 (1), pp. 250. Date of Electronic Publication: 2022 Oct 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Quinolones*
Salmonella enterica*
Typhoid Fever*
Amino Acids ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Ciprofloxacin/pharmacology ; DNA Gyrase/genetics ; DNA Topoisomerase IV/genetics ; Drug Resistance, Bacterial/genetics ; Fluoroquinolones/pharmacology ; Humans ; Levofloxacin ; Microbial Sensitivity Tests ; Moxifloxacin ; Nalidixic Acid ; Salmonella ; Salmonella typhi
SCR Organism:: Salmonella enterica subsp. enterica

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Skocz do pozycji: 13.

Tytuł:: Design, Synthesis, Antibacterial Evaluations and In Silico Studies of Novel Thiosemicarbazides and 1,3,4-Thiadiazoles.
Autorzy:: Janowska S; Department of Organic Chemistry, Faculty of Pharmacy, Medical University, 20-093 Lublin, Poland.
Khylyuk D; Department of Organic Chemistry, Faculty of Pharmacy, Medical University, 20-093 Lublin, Poland.
Andrzejczuk S; Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Medical University, 20-093 Lublin, Poland.
Wujec M; Department of Organic Chemistry, Faculty of Pharmacy, Medical University, 20-093 Lublin, Poland.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 May 15; Vol. 27 (10). Date of Electronic Publication: 2022 May 15.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Bacterial Agents*/chemistry
Thiadiazoles*/pharmacology
DNA Gyrase/metabolism ; DNA Topoisomerase IV ; Gram-Negative Bacteria/metabolism ; Gram-Positive Bacteria/metabolism ; Molecular Docking Simulation ; Semicarbazides

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Skocz do pozycji: 14.

Tytuł:: Comparison of the first whole genome sequence of 'Haemophilus quentini' with two new strains of 'Haemophilus quentini' and other species of Haemophilus.
Autorzy:: Hubbard ATM; a Micropathology Ltd., University of Warwick Science Park, Coventry, United Kingdom.
Davies SEW; a Micropathology Ltd., University of Warwick Science Park, Coventry, United Kingdom.
Baxter L; b School of Life Sciences, University of Warwick, Coventry, United Kingdom.
Thompson S; c Microbiology Department, Sheffield Teaching Hospitals NHS Foundation Trust, Northern General Hospital, Sheffield, United Kingdom.
Collery MM; a Micropathology Ltd., University of Warwick Science Park, Coventry, United Kingdom.
Hand DC; a Micropathology Ltd., University of Warwick Science Park, Coventry, United Kingdom.
Thomas DJI; a Micropathology Ltd., University of Warwick Science Park, Coventry, United Kingdom.
Fink CG; a Micropathology Ltd., University of Warwick Science Park, Coventry, United Kingdom.; Pokaż więcej
Źródło:: Genome [Genome] 2018 May; Vol. 61 (5), pp. 379-385. Date of Electronic Publication: 2018 Mar 13.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Genome, Bacterial*
DNA Gyrase/*genetics
DNA Topoisomerase IV/*genetics
Haemophilus/*genetics
Haemophilus influenzae/*genetics
DNA Gyrase/metabolism ; DNA Topoisomerase IV/metabolism ; Gene Expression ; Genetic Variation ; Haemophilus/classification ; Haemophilus/metabolism ; Haemophilus influenzae/classification ; Haemophilus influenzae/metabolism ; Multilocus Sequence Typing ; Phylogeny ; Whole Genome Sequencing

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Skocz do pozycji: 15.

Tytuł:: A novel parC mutation potentiating fluoroquinolone resistance in Klebsiella pneumoniae and Escherichia coli clinical isolates.
Autorzy:: Yakout MA; Department of Microbiology and immunology, Faculty of pharmacy, Pharos University in Alexandria, Alexandria, Egypt. .
Ali GH; Department of Microbiology and immunology, Faculty of pharmacy, Pharos University in Alexandria, Alexandria, Egypt.; Pokaż więcej
Źródło:: Journal of infection in developing countries [J Infect Dev Ctries] 2022 Feb 28; Vol. 16 (2), pp. 314-319. Date of Electronic Publication: 2022 Feb 28.
Typ publikacji:: Journal Article
MeSH Terms:: Fluoroquinolones*/pharmacology
Klebsiella pneumoniae*/genetics
Anti-Bacterial Agents/pharmacology ; DNA Gyrase/genetics ; DNA Topoisomerase IV/genetics ; Escherichia coli/genetics ; Mutation

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Skocz do pozycji: 16.

Tytuł:: Antimicrobial Resistance and Whole-Genome Characterisation of High-Level Ciprofloxacin-Resistant Salmonella Enterica Serovar Kentucky ST 198 Strains Isolated from Human in Poland.
Autorzy:: Wołkowicz T; Department of Bacteriology and Biocontamination Control, National Institute of Public Health NIH-National Research Institute, 00-791 Warsaw, Poland.
Zacharczuk K; Department of Bacteriology and Biocontamination Control, National Institute of Public Health NIH-National Research Institute, 00-791 Warsaw, Poland.
Gierczyński R; Department of Bacteriology and Biocontamination Control, National Institute of Public Health NIH-National Research Institute, 00-791 Warsaw, Poland.
Nowakowska M; Department of Bacteriology and Biocontamination Control, National Institute of Public Health NIH-National Research Institute, 00-791 Warsaw, Poland.
Piekarska K; Department of Bacteriology and Biocontamination Control, National Institute of Public Health NIH-National Research Institute, 00-791 Warsaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 29; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 29.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Bacterial Agents/*pharmacology
Ciprofloxacin/*pharmacology
Drug Resistance, Bacterial/*genetics
Salmonella enterica/*drug effects
Salmonella enterica/*genetics
Bacterial Proteins/genetics ; Bacterial Typing Techniques ; DNA Gyrase/genetics ; DNA Topoisomerase IV/genetics ; Drug Resistance, Bacterial/drug effects ; Genome, Bacterial ; Humans ; Microbial Sensitivity Tests ; Multilocus Sequence Typing ; Mutation ; Phylogeny ; Poland ; Polymorphism, Single Nucleotide ; Salmonella Infections/microbiology ; Salmonella enterica/classification ; Salmonella enterica/isolation & purification ; Whole Genome Sequencing

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Skocz do pozycji: 17.

Tytuł:: Synthesis, Molecular Docking, and Biofilm Formation Inhibitory Activity of Bis(Indolyl)Pyridines Analogues of the Marine Alkaloid Nortopsentin.
Autorzy:: Abo-Salem HM; Chemistry of Natural Compounds Department, National Research Centre, Dokki, Giza 12622, Egypt.
Abd El Salam HA; Green Chemistry Department, National Research Centre, Dokki, Giza 12622, Egypt.
Abdel-Aziem AM; Chemistry Department, Faculty of Science (Girl's Branch), Al-Azhar University, Cairo 11284, Egypt.
Abdel-Aziz MS; Microbial Chemistry Department, Genetic Engineering and biotechnology Division, National Research Centre, Dokki, Giza 12622, Egypt.
El-Sawy ER; Chemistry of Natural Compounds Department, National Research Centre, Dokki, Giza 12622, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Jul 06; Vol. 26 (14). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji:: Journal Article
MeSH Terms:: Alkaloids/*chemistry
Anti-Bacterial Agents/*chemical synthesis
Anti-Bacterial Agents/*pharmacology
Bacteria/*drug effects
Biofilms/*growth & development
Enzyme Inhibitors/*pharmacology
Indoles/*chemistry
Biofilms/drug effects ; DNA Gyrase/chemistry ; DNA Topoisomerase IV/antagonists & inhibitors ; Enzyme Inhibitors/chemistry ; Molecular Docking Simulation ; Nucleoside-Phosphate Kinase/antagonists & inhibitors ; Pyridines/chemistry

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Skocz do pozycji: 18.

Tytuł:: Mapping Topoisomerase IV Binding and Activity Sites on the E. coli Genome.
Autorzy:: El Sayyed H; Center for Interdisciplinary Research in Biology (CIRB), Collège de France, UMR-CNRS 7241, Paris, France.; Université Paris-Saclay, Gif-sur-Yvette, France.
Le Chat L; Center for Interdisciplinary Research in Biology (CIRB), Collège de France, UMR-CNRS 7241, Paris, France.
Lebailly E; Laboratoire de Microbiologie et de Génétique Moléculaires (LMGM), CNRS-Université Toulouse III, Toulouse, France.
Vickridge E; Center for Interdisciplinary Research in Biology (CIRB), Collège de France, UMR-CNRS 7241, Paris, France.; Université Paris-Saclay, Gif-sur-Yvette, France.
Pages C; Laboratoire de Microbiologie et de Génétique Moléculaires (LMGM), CNRS-Université Toulouse III, Toulouse, France.
Cornet F; Laboratoire de Microbiologie et de Génétique Moléculaires (LMGM), CNRS-Université Toulouse III, Toulouse, France.
Cosentino Lagomarsino M; UMR 7238, Computational and quantitative biology, Institut de biologie Paris Seine, Paris, France.
Espéli O; Center for Interdisciplinary Research in Biology (CIRB), Collège de France, UMR-CNRS 7241, Paris, France.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2016 May 12; Vol. 12 (5), pp. e1006025. Date of Electronic Publication: 2016 May 12 (Print Publication: 2016).
Typ publikacji:: Journal Article
MeSH Terms:: Chromosomal Proteins, Non-Histone/*genetics
DNA Replication/*genetics
DNA Topoisomerase IV/*genetics
Escherichia coli Proteins/*genetics
Integrases/*genetics
Binding Sites/genetics ; Catalytic Domain/genetics ; Cell Cycle/genetics ; Cell Division/genetics ; Chromatids/genetics ; Chromosomal Proteins, Non-Histone/metabolism ; Chromosome Segregation/genetics ; Chromosomes, Bacterial/genetics ; DNA Topoisomerase IV/metabolism ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Escherichia coli Proteins/metabolism ; Integrases/metabolism ; Sister Chromatid Exchange/genetics

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Tytuł:: Macrolide and fluoroquinolone associated mutations in Mycoplasma genitalium in a retrospective study of male and female patients seeking care at a STI Clinic in Guangzhou, China, 2016-2018.
Autorzy:: Ke W; Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.; Department of Sexually Transmitted Diseases, Guangdong Provincial Dermatology Hospital, Guangzhou, 510095, China.
Li D; Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.; Department of Sexually Transmitted Diseases, Guangdong Provincial Dermatology Hospital, Guangzhou, 510095, China.
Tso LS; Department of Culture Studies and Oriental Languages, University of Oslo, 0315, Oslo, Norway.; Anthropology, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.; Center for Health and Human Development Studies, Sun Yat-Sen University, Guangzhou, 510275, China.
Wei R; Department of Dermatovenerology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Lan Y; Clinical Laboratory, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.
Chen Z; Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.; Department of Sexually Transmitted Diseases, Guangdong Provincial Dermatology Hospital, Guangzhou, 510095, China.
Zhang X; Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.; Department of Sexually Transmitted Diseases, Guangdong Provincial Dermatology Hospital, Guangzhou, 510095, China.
Wang L; Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.; Department of Sexually Transmitted Diseases, Guangdong Provincial Dermatology Hospital, Guangzhou, 510095, China.
Liang C; Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.; Department of Sexually Transmitted Diseases, Guangdong Provincial Dermatology Hospital, Guangzhou, 510095, China.
Liao Y; Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.; Department of Sexually Transmitted Diseases, Guangdong Provincial Dermatology Hospital, Guangzhou, 510095, China.
Chen H; Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China.; Department of Sexually Transmitted Diseases, Guangdong Provincial Dermatology Hospital, Guangzhou, 510095, China.
Liu Y; Department of Dermatology, Qingyuan Chronic Disease Prevention Hospital, Qingyuan, 511500, China.
Zheng H; Clinical Laboratory, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China. .; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, Guangdong, China. .
Yang L; Department of Sexually Transmitted Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510095, China. .; Department of Sexually Transmitted Diseases, Guangdong Provincial Dermatology Hospital, Guangzhou, 510095, China. .; Dermatology Hospital, Southern Medical University, Guangzhou, 510091, Guangdong, China. .; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2020 Dec 11; Vol. 20 (1), pp. 950. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji:: Journal Article
MeSH Terms:: Mutation*
Anti-Bacterial Agents/*therapeutic use
Drug Resistance, Multiple, Bacterial/*genetics
Fluoroquinolones/*therapeutic use
Macrolides/*therapeutic use
Mycoplasma Infections/*drug therapy
Mycoplasma genitalium/*genetics
Sexually Transmitted Diseases, Bacterial/*drug therapy
China/epidemiology ; DNA Gyrase/genetics ; DNA Topoisomerase IV/genetics ; DNA, Bacterial/genetics ; Drug Resistance, Multiple, Bacterial/drug effects ; Female ; Humans ; Male ; Mycoplasma Infections/epidemiology ; Mycoplasma Infections/microbiology ; Mycoplasma genitalium/isolation & purification ; Prevalence ; RNA, Ribosomal, 23S/genetics ; Real-Time Polymerase Chain Reaction ; Retrospective Studies ; Sexually Transmitted Diseases, Bacterial/epidemiology ; Sexually Transmitted Diseases, Bacterial/microbiology

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Tytuł:: Fluoroquinolone resistance of Staphylococcus epidermidis isolated from healthy conjunctiva and analysis of their mutations in quinolone-resistance determining region.
Autorzy:: Kang JY; Department of Ophthalmology, Kosin University College of Medicine, 262 Gamchun-ro, Seo-gu, Busan, South Korea.
Lee W; Department of Laboratory Medicine, Kosin University College of Medicine, Busan, South Korea.
Noh GM; Department of Ophthalmology, Kosin University College of Medicine, 262 Gamchun-ro, Seo-gu, Busan, South Korea.
Jeong BH; Department of Microbiology, Kosin University College of Medicine, Busan, South Korea.
Park I; Department of Microbiology, Kosin University College of Medicine, Busan, South Korea.
Lee SJ; Department of Ophthalmology, Kosin University College of Medicine, 262 Gamchun-ro, Seo-gu, Busan, South Korea. .; Pokaż więcej
Źródło:: Antimicrobial resistance and infection control [Antimicrob Resist Infect Control] 2020 Nov 04; Vol. 9 (1), pp. 177. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji:: Journal Article
MeSH Terms:: Mutation*
Conjunctiva/*microbiology
Fluoroquinolones/*pharmacology
Staphylococcus epidermidis/*drug effects
DNA Gyrase/genetics ; DNA Topoisomerase IV/genetics ; Drug Resistance, Bacterial/genetics ; Staphylococcus epidermidis/genetics

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