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Tytuł :
Targeted next-generation sequencing of sputum for diagnosis of drug-resistant TB: results of a national survey in Democratic Republic of the Congo.
Autorzy :
Kayomo MK; National Tuberculosis Program et Laboratoire National de Référence des Mycobactéries (LNRM), Kinshasa, Democratic Republic of the Congo.; Faculté de Médecine, Université de Kinshasa, Kinshasa, Democratic Republic of the Congo.
Mbula VN; National Tuberculosis Program et Laboratoire National de Référence des Mycobactéries (LNRM), Kinshasa, Democratic Republic of the Congo.
Aloni M; National Tuberculosis Program et Laboratoire National de Référence des Mycobactéries (LNRM), Kinshasa, Democratic Republic of the Congo.; Faculté de Médecine, Université de Kinshasa, Kinshasa, Democratic Republic of the Congo.
André E; Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Rigouts L; Institute of Tropical Medicine, Antwerp, Belgium.; Antwerp University, Antwerp, Belgium.
Boutachkourt F; Pôle de Microbiologie Médicale, Institut de Recherche Expérimental Et Clinique, UC Louvain, Brussels, Belgium.
de Jong BC; Institute of Tropical Medicine, Antwerp, Belgium.
Nkiere NM; World Health Organization, Kinshasa, Democratic Republic of the Congo.
Dean AS; Global TB Programme, World Health Organization, Geneva, Switzerland. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 01; Vol. 10 (1), pp. 10786. Date of Electronic Publication: 2020 Jul 01.
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
High-Throughput Nucleotide Sequencing*
Tuberculosis, Multidrug-Resistant*/diagnosis
Tuberculosis, Multidrug-Resistant*/drug therapy
Tuberculosis, Multidrug-Resistant*/epidemiology
Tuberculosis, Multidrug-Resistant*/genetics
Mycobacterium tuberculosis/*genetics
Sputum/*microbiology
Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Cross-Sectional Studies ; Democratic Republic of the Congo/epidemiology ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Prevalence ; Tuberculosis, Pulmonary/diagnosis ; Tuberculosis, Pulmonary/drug therapy ; Tuberculosis, Pulmonary/epidemiology ; Tuberculosis, Pulmonary/genetics
Czasopismo naukowe
Tytuł :
The predicted impact of tuberculosis preventive therapy: the importance of disease progression assumptions.
Autorzy :
Sumner T; TB Modelling Group, TB Centre, Centre for Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK. .
White RG; TB Modelling Group, TB Centre, Centre for Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2020 Nov 23; Vol. 20 (1), pp. 880. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotic Prophylaxis*
Models, Theoretical*
Mycobacterium tuberculosis*
Antitubercular Agents/*therapeutic use
Tuberculosis/*epidemiology
Tuberculosis/*prevention & control
Disease Progression ; Humans ; Incidence ; Risk ; Treatment Outcome ; Tuberculosis/microbiology ; Uncertainty
Czasopismo naukowe
Tytuł :
Clinical variables and gene signatures in tuberculosis.
Autorzy :
Acuña-Villaorduña C; Section of Infectious Diseases, Department of Medicine, Boston Medical Center and Boston University School of Medicine, Boston, MA 02118, USA; Section of Infectious Diseases, Lemuel Shattuck Hospital, Jamaica Plain, MA, USA. Electronic address: .
Jones-López EC; Section of Infectious Diseases, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Salgame P; Centre for Emerging Pathogens, Department of Medicine, Rutgers-New Jersey Medical School, Newark, NJ, USA.
Dietze R; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil; Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.
Ellner JJ; Centre for Emerging Pathogens, Department of Medicine, Rutgers-New Jersey Medical School, Newark, NJ, USA.
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Źródło :
The Lancet. Infectious diseases [Lancet Infect Dis] 2020 Nov; Vol. 20 (11), pp. 1227-1229.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Contact Tracing*
Mycobacterium tuberculosis*
Transcriptome*
Latent Tuberculosis/*genetics
Tuberculosis, Pulmonary/*epidemiology
Tuberculosis, Pulmonary/*transmission
Adolescent ; Disease Progression ; Humans ; Latent Tuberculosis/microbiology ; Mass Chest X-Ray ; Prognosis ; Research Design ; Triage/methods ; Tuberculosis, Pulmonary/microbiology ; Tuberculosis, Pulmonary/prevention & control
Czasopismo naukowe
Tytuł :
Patient delay in the diagnosis of tuberculosis in Ethiopia: a systematic review and meta-analysis.
Autorzy :
Alene M; Department of Public Health, Debre Markos University, Debre Markos, Ethiopia. .
Assemie MA; Department of Public Health, Debre Markos University, Debre Markos, Ethiopia.
Yismaw L; Department of Public Health, Debre Markos University, Debre Markos, Ethiopia.
Gedif G; Department of Public Health, Debre Markos University, Debre Markos, Ethiopia.
Ketema DB; Department of Public Health, Debre Markos University, Debre Markos, Ethiopia.
Gietaneh W; Department of Public Health, Debre Markos University, Debre Markos, Ethiopia.
Chekol TD; School of Medicine, Debre Markos University, Debre Markos, Ethiopia.
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2020 Oct 27; Vol. 20 (1), pp. 797. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Delayed Diagnosis*
Mycobacterium tuberculosis*
Tuberculosis, Pulmonary/*diagnosis
Tuberculosis, Pulmonary/*epidemiology
Age Factors ; Attitude to Health ; Awareness ; Ethiopia/epidemiology ; Health Facilities ; Humans ; Risk Factors ; Rural Population ; Time Factors ; Tuberculosis, Pulmonary/microbiology
Czasopismo naukowe
Tytuł :
Completeness of tuberculosis case notifications in Germany in 2013-2017: first results of an inventory study.
Autorzy :
Domaszewska T; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany. .
Karo B; Robert Koch Institute, Centre for International Health Protection (ZIG), Berlin, Germany.
Preuss U; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Kollan C; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Reuss A; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Blank HP; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Brodhun B; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Hauer B; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Altmann D; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Fiebig L; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.; Current affiliation: APOPO, Sokoine University of Agriculture, Morogoro, Tanzania.
Haas W; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Perumal N; Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2020 Oct 17; Vol. 20 (1), pp. 766. Date of Electronic Publication: 2020 Oct 17.
Typ publikacji :
Journal Article
MeSH Terms :
Mycobacterium tuberculosis*
Antitubercular Agents/*therapeutic use
Pyrazinamide/*therapeutic use
Tuberculosis/*drug therapy
Tuberculosis/*epidemiology
Databases, Factual ; Disease Notification/methods ; Germany ; Humans ; Incidence ; Information Storage and Retrieval ; Length of Stay ; Tuberculosis/microbiology
Czasopismo naukowe
Tytuł :
The epidemiology of tuberculosis-associated hyperglycemia in individuals newly screened for type 2 diabetes mellitus: systematic review and meta-analysis.
Autorzy :
Menon S; Global Health Institute, University of Antwerp, Antwerp, Belgium. .; Department of Public Health, Institute of Tropical Medicine, Sint Rochusstraat 43, 2000, Antwerp, Belgium. .
Rossi R; International Committee of the Red Cross, Geneva, Switzerland.
Dusabimana A; Global Health Institute, University of Antwerp, Antwerp, Belgium.
Zdraveska N; Specialized hospital for Geriatric and Palliative medicine, Skopje, Republic of North Macedonia.
Bhattacharyya S; Department of Mathematics, School of Natural Sciences, Shiv Nadar University, Uttar Pradesh, India.
Francis J; Department of Family Medicine and Primary Care, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2020 Dec 09; Vol. 20 (1), pp. 937. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Mycobacterium tuberculosis*
Diabetes Mellitus, Type 2/*diagnosis
Diabetes Mellitus, Type 2/*epidemiology
Hyperglycemia/*epidemiology
Tuberculosis, Pulmonary/*epidemiology
Adolescent ; Adult ; Africa South of the Sahara/epidemiology ; Aged ; Aged, 80 and over ; Female ; Follow-Up Studies ; Global Health ; Humans ; Male ; Mass Screening ; Middle Aged ; Middle East/epidemiology ; Prospective Studies ; Risk Factors ; Tuberculosis, Pulmonary/microbiology ; Young Adult
Czasopismo naukowe
Tytuł :
Incident tuberculosis disease in patients receiving biologic therapies in the Western Cape, South Africa from 2007 to 2018.
Autorzy :
du Toit T; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, Republic of South Africa.
Esterhuizen TM; Division of Epidemiology and Biostatistics, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch, South Africa.
Tiffin N; Computational Biology Division, Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa.; Wellcome Centre for Infectious Disease Research in Africa, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.; Centre for Infectious Disease Epidemiology Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
Abulfathi AA; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, Republic of South Africa.; Department of Clinical Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria.
Reuter H; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, Republic of South Africa.
Decloedt EH; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, Republic of South Africa. .
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2020 Nov 30; Vol. 20 (1), pp. 900. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article
MeSH Terms :
Mycobacterium tuberculosis*
Antibodies, Monoclonal, Humanized/*adverse effects
Antirheumatic Agents/*adverse effects
Biological Products/*adverse effects
Biological Therapy/*adverse effects
Tuberculosis/*epidemiology
Adolescent ; Adult ; Antibodies, Monoclonal, Humanized/pharmacology ; Antirheumatic Agents/pharmacology ; Biological Products/pharmacology ; Female ; Follow-Up Studies ; Humans ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; South Africa/epidemiology ; Tuberculosis/microbiology ; Tumor Necrosis Factor-alpha/antagonists & inhibitors ; Young Adult
Czasopismo naukowe
Tytuł :
Using Cure Models to Estimate the Serial Interval of Tuberculosis With Limited Follow-up.
Autorzy :
Ma Y
Jenkins HE
Sebastiani P
Ellner JJ
Jones-López EC
Dietze R
Horsburgh CR Jr
White LF
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Źródło :
American journal of epidemiology [Am J Epidemiol] 2020 Nov 02; Vol. 189 (11), pp. 1421-1426.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Mycobacterium tuberculosis*
Time Factors*
Biostatistics/*methods
Disease Transmission, Infectious/*statistics & numerical data
Tuberculosis/*transmission
Brazil/epidemiology ; Canada/epidemiology ; Humans ; Tuberculosis/epidemiology ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Comparing tuberculosis gene signatures in malnourished individuals using the TBSignatureProfiler.
Autorzy :
Johnson WE; Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. .; Bioinformatics Program, Boston University, Boston, MA, USA. .; Division of Computational Biomedicine and Bioinformatics Program, Boston University, Boston, MA, USA. .
Odom A; Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA.; Bioinformatics Program, Boston University, Boston, MA, USA.; Division of Computational Biomedicine and Bioinformatics Program, Boston University, Boston, MA, USA.
Cintron C; Boston Medical Center, Boston, MA, USA.
Muthaiah M; Government Hospital for Chest Diseases, Puducherry, India.
Knudsen S; Boston Medical Center, Boston, MA, USA.
Joseph N; Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Babu S; Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Lakshminarayanan S; Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Jenkins DF; Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA.; Bioinformatics Program, Boston University, Boston, MA, USA.; Division of Computational Biomedicine and Bioinformatics Program, Boston University, Boston, MA, USA.
Zhao Y; Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA.; Bioinformatics Program, Boston University, Boston, MA, USA.; Division of Computational Biomedicine and Bioinformatics Program, Boston University, Boston, MA, USA.
Nankya E; Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA.; Bioinformatics Program, Boston University, Boston, MA, USA.; Division of Computational Biomedicine and Bioinformatics Program, Boston University, Boston, MA, USA.
Horsburgh CR; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Roy G; Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Ellner J; Department of Medicine, Center for Emerging Pathogens, Rutgers New Jersey Medical School, Newark, NJ, USA.
Sarkar S; Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Salgame P; Department of Medicine, Center for Emerging Pathogens, Rutgers New Jersey Medical School, Newark, NJ, USA.
Hochberg NS; Boston Medical Center, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.; Section of Infectious Diseases, Boston University School of Medicine, Boston, MA, USA.
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Jan 22; Vol. 21 (1), pp. 106. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
Software*
Gene Expression Profiling/*methods
Malnutrition/*genetics
Tuberculosis/*genetics
Adolescent ; Adult ; Aged ; Area Under Curve ; Biomarkers/blood ; Child ; Comorbidity ; Female ; Humans ; Latent Tuberculosis/diagnosis ; Latent Tuberculosis/epidemiology ; Latent Tuberculosis/genetics ; Male ; Malnutrition/diagnosis ; Malnutrition/epidemiology ; Middle Aged ; Mycobacterium tuberculosis ; Transcriptome ; Tuberculosis/diagnosis ; Tuberculosis/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
Initiation of Post-Primary Tuberculosis of the Lungs: Exploring the Secret Role of Bone Marrow Derived Stem Cells.
Autorzy :
Pathak L; Department of Stem Cell and Infectious Diseases, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, India.; KaviKrishna Telemedicine Care, Sualkuchi, India.
Das B; Department of Stem Cell and Infectious Diseases, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, India.; KaviKrishna Telemedicine Care, Sualkuchi, India.; Department of Stem Cell and Infection, Thoreau Laboratory for Global Health, M2D2, University of Massachusetts, Lowell, MA, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Jan 21; Vol. 11, pp. 594572. Date of Electronic Publication: 2021 Jan 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Review
MeSH Terms :
Tuberculosis, Pulmonary*/microbiology
Tuberculosis, Pulmonary*/transmission
Bone Marrow Cells/*microbiology
Mycobacterium tuberculosis/*physiology
Virus Activation/*physiology
Virus Latency/*physiology
COVID-19 ; Humans ; Mesenchymal Stem Cells/microbiology ; SARS-CoV-2 ; Stem Cell Niche/physiology
Czasopismo naukowe
Tytuł :
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults.
Autorzy :
Kohli M; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada.
Schiller I; Centre for Outcomes Research, McGill University Health Centre - Research Institute, Montreal, Canada.
Dendukuri N; Centre for Outcomes Research, McGill University Health Centre - Research Institute, Montreal, Canada.
Yao M; Centre for Outcomes Research, McGill University Health Centre - Research Institute, Montreal, Canada.
Dheda K; Centre for Lung Infection and Immunity Unit, Department of Medicine and UCT Lung Institute, University of Cape Town, Cape Town, South Africa.; Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, UK.
Denkinger CM; FIND, Geneva , Switzerland.; Division of Tropical Medicine, Centre for Infectious Diseases, University Hospital Heidelberg, Heidelberg, Germany.
Schumacher SG; FIND, Geneva , Switzerland.
Steingart KR; Honorary Research Fellow, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
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Źródło :
The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2021 Jan 15; Vol. 1. Cochrane AN: CD012768. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Drug Resistance, Bacterial*
Nucleic Acid Amplification Techniques*/methods
Nucleic Acid Amplification Techniques*/statistics & numerical data
Antibiotics, Antitubercular/*therapeutic use
Mycobacterium tuberculosis/*drug effects
Rifampin/*therapeutic use
Tuberculosis/*diagnosis
Adult ; Bias ; False Negative Reactions ; False Positive Reactions ; Humans ; Mycobacterium tuberculosis/isolation & purification ; Reagent Kits, Diagnostic ; Sensitivity and Specificity ; Tuberculosis/cerebrospinal fluid ; Tuberculosis/drug therapy ; Tuberculosis, Lymph Node/cerebrospinal fluid ; Tuberculosis, Lymph Node/diagnosis ; Tuberculosis, Lymph Node/drug therapy ; Tuberculosis, Meningeal/cerebrospinal fluid ; Tuberculosis, Meningeal/diagnosis ; Tuberculosis, Meningeal/drug therapy ; Tuberculosis, Multidrug-Resistant/cerebrospinal fluid ; Tuberculosis, Multidrug-Resistant/diagnosis ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Pleural/cerebrospinal fluid ; Tuberculosis, Pleural/diagnosis ; Tuberculosis, Pleural/drug therapy
Czasopismo naukowe
Tytuł :
Diagnostic accuracy of a liquid chromatography-tandem mass spectrometry assay in small hair samples for rifampin-resistant tuberculosis drug concentrations in a routine care setting.
Autorzy :
Metcalfe J; Division of Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, University of California, San Francisco, 1001 Potrero Avenue, Rm 5K1, San Francisco, CA, 94110-0111, USA. .
Bacchetti P; Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, USA.
Esmail A; Lung Infection and Immunity Unit, Division of Pulmonology, University of Cape Town, Cape Town, South Africa.
Reckers A; Maternal-Fetal Medicine Division, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA, USA.
Aguilar D; Maternal-Fetal Medicine Division, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA, USA.
Wen A; Maternal-Fetal Medicine Division, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA, USA.
Huo S; Division of Pulmonary and Critical Care Medicine, Zuckerberg San Francisco General Hospital and Trauma Center, University of California, San Francisco, 1001 Potrero Avenue, Rm 5K1, San Francisco, CA, 94110-0111, USA.
Muyindike WR; Mbarara University of Science and Technology, Mbarara, Uganda.
Hahn JA; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, UCSF, San Francisco, CA, USA.
Dheda K; Lung Infection and Immunity Unit, Division of Pulmonology, University of Cape Town, Cape Town, South Africa.
Gandhi M; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, UCSF, San Francisco, CA, USA.
Gerona R; Maternal-Fetal Medicine Division, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, CA, USA.
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Jan 22; Vol. 21 (1), pp. 99. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Antitubercular Agents/*analysis
Drug Monitoring/*methods
Hair/*chemistry
Rifampin/*pharmacology
Tuberculosis, Multidrug-Resistant/*drug therapy
Adult ; Antitubercular Agents/therapeutic use ; Chromatography, Liquid ; Female ; Humans ; Male ; Middle Aged ; Mycobacterium tuberculosis/drug effects ; Sensitivity and Specificity ; Tandem Mass Spectrometry ; Tuberculosis/drug therapy
Czasopismo naukowe
Tytuł :
Modelling the global burden of drug-resistant tuberculosis avertable by a post-exposure vaccine.
Autorzy :
Fu H; MRC Centre for Global Infectious Disease Analysis; and the Abdul Latif Jameel Institute for Disease and Emergency Analytics (J-IDEA), School of Public Health, Imperial College London, London, W2 1PG, UK. .
Lewnard JA; Division of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, CA, 94720, USA.
Frost I; Center for Disease Dynamics, Economics & Policy, New Delhi, India.; Department of Infectious Disease, Imperial College London, London, W2 1NY, UK.
Laxminarayan R; Center for Disease Dynamics, Economics & Policy, New Delhi, India.; Princeton University, Princeton, NJ, 08544, USA.
Arinaminpathy N; MRC Centre for Global Infectious Disease Analysis; and the Abdul Latif Jameel Institute for Disease and Emergency Analytics (J-IDEA), School of Public Health, Imperial College London, London, W2 1PG, UK.
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Źródło :
Nature communications [Nat Commun] 2021 Jan 18; Vol. 12 (1), pp. 424. Date of Electronic Publication: 2021 Jan 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Global Burden of Disease*
Antitubercular Agents/*pharmacology
Post-Exposure Prophylaxis/*methods
Tuberculosis/*epidemiology
Tuberculosis Vaccines/*administration & dosage
Adolescent ; Adult ; Antitubercular Agents/therapeutic use ; Computer Simulation ; Drug Resistance, Bacterial/immunology ; Humans ; Incidence ; Models, Statistical ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/immunology ; Mycobacterium tuberculosis/isolation & purification ; Rifampin/pharmacology ; Rifampin/therapeutic use ; Tuberculosis/drug therapy ; Tuberculosis/microbiology ; Tuberculosis/prevention & control
Czasopismo naukowe
Tytuł :
Gene network in pulmonary tuberculosis based on bioinformatic analysis.
Autorzy :
Li L; Central Laboratory, Renmin Hospital of Wuhan University, 95 Zhangzhidong Rd. Wuchang District, Wuhan, 430060, China.
Lv J; Central Laboratory, Renmin Hospital of Wuhan University, 95 Zhangzhidong Rd. Wuchang District, Wuhan, 430060, China.
He Y; Central Laboratory, Renmin Hospital of Wuhan University, 95 Zhangzhidong Rd. Wuchang District, Wuhan, 430060, China.
Wang Z; Central Laboratory, Renmin Hospital of Wuhan University, 95 Zhangzhidong Rd. Wuchang District, Wuhan, 430060, China. .; Department of Cardiology, Renmin Hospital of Wuhan University, 95 Zhangzhidong Rd. Wuchang District, Wuhan, 430060, China. .
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2020 Aug 18; Vol. 20 (1), pp. 612. Date of Electronic Publication: 2020 Aug 18.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Regulatory Networks*
Mycobacterium tuberculosis*
Transcriptome*
Computational Biology/*methods
Protein Interaction Maps/*genetics
Tuberculosis, Pulmonary/*genetics
Biomarkers ; Cohort Studies ; Gene Expression Profiling ; Gene Expression Regulation/drug effects ; Humans ; Signal Transduction/genetics ; Tuberculosis, Pulmonary/diagnosis ; Tuberculosis, Pulmonary/drug therapy ; Tuberculosis, Pulmonary/microbiology
Czasopismo naukowe
Tytuł :
Utility of broad-spectrum antibiotics for diagnosing pulmonary tuberculosis in adults: a systematic review and meta-analysis.
Autorzy :
Divala TH; TB Centre, London School of Hygiene & Tropical Medicine, London, UK; Helse Nord Tuberculosis Initiative, University of Malawi College of Medicine, Blantyre, Malawi; Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi. Electronic address: .
Fielding KL; TB Centre, London School of Hygiene & Tropical Medicine, London, UK; School of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
Kandulu C; Helse Nord Tuberculosis Initiative, University of Malawi College of Medicine, Blantyre, Malawi; Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Nliwasa M; TB Centre, London School of Hygiene & Tropical Medicine, London, UK; Helse Nord Tuberculosis Initiative, University of Malawi College of Medicine, Blantyre, Malawi; Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Sloan DJ; School of Medicine, University of St Andrews, St Andrews, UK.
Gupta-Wright A; TB Centre, London School of Hygiene & Tropical Medicine, London, UK; Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Corbett EL; TB Centre, London School of Hygiene & Tropical Medicine, London, UK; Helse Nord Tuberculosis Initiative, University of Malawi College of Medicine, Blantyre, Malawi; Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
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Źródło :
The Lancet. Infectious diseases [Lancet Infect Dis] 2020 Sep; Vol. 20 (9), pp. 1089-1098. Date of Electronic Publication: 2020 May 18.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Anti-Bacterial Agents*/pharmacology
Anti-Bacterial Agents*/therapeutic use
Mycobacterium tuberculosis*/drug effects
Tuberculosis, Pulmonary/*diagnosis
Tuberculosis, Pulmonary/*microbiology
Adult ; Coinfection ; HIV Infections/virology ; Humans ; Microbial Sensitivity Tests ; ROC Curve ; Sensitivity and Specificity ; Tuberculosis, Pulmonary/drug therapy
Czasopismo naukowe
Tytuł :
Lineage-specific differences in lipid metabolism and its impact on clinical strains of Mycobacterium tuberculosis.
Autorzy :
Moopanar K; School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, South Africa. Electronic address: .
Mvubu NE; School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, South Africa. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2020 Sep; Vol. 146, pp. 104250. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Mycobacterium tuberculosis*/genetics
Mycobacterium tuberculosis*/metabolism
Mycobacterium tuberculosis*/pathogenicity
Lipid Metabolism/*genetics
Cell Wall/chemistry ; Cell Wall/metabolism ; Drug Delivery Systems ; Fatty Acids/metabolism ; Genetic Variation ; Genome, Bacterial ; Host Microbial Interactions ; Humans ; Lipids/chemistry ; Macrophages/immunology ; Macrophages/microbiology ; Phagocytosis ; Phylogeny ; Tuberculosis/drug therapy ; Tuberculosis/transmission ; Virulence/genetics
Czasopismo naukowe
Tytuł :
A rare case of primary sinonasal tuberculosis presented with phlyctenular keratoconjunctivitis in a pediatric patient: A case report and literature review.
Autorzy :
Wiriyachai T; Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok.
Boonsathorn S; Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok.
Apiwattanakul N; Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok.
Assawawiroonhakarn S; Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok.; Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan, Thailand.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Feb 19; Vol. 100 (7), pp. e24787.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Keratoconjunctivitis/*etiology
Paranasal Sinus Diseases/*diagnosis
Tuberculosis/*diagnosis
Antibiotics, Antitubercular/therapeutic use ; Child ; Child, Preschool ; Female ; Humans ; Isoniazid/therapeutic use ; Male ; Mycobacterium tuberculosis/isolation & purification ; Orbit/diagnostic imaging ; Orbit/pathology ; Paranasal Sinus Diseases/complications ; Paranasal Sinus Diseases/drug therapy ; Rifampin/therapeutic use ; Tomography, X-Ray Computed ; Tuberculosis/complications ; Tuberculosis/drug therapy
Czasopismo naukowe
Tytuł :
Diagnosis of Tuberculosis Using Gastric Aspirates in Pediatric Patients in Haiti.
Autorzy :
Pierre-Louis MH; Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Rouzier V; Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Rivera V; Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Systrom HK; Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire, USA.
Julma P; Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Jean E; Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Francois LC; Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Pape JW; Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Ocheretina O; Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-au-Prince, Haiti.
Wright PF; Division of Infectious Disease and International Health, Dartmouth Hitchcock Medical Center, Lebanon New Hampshire, USA.
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Źródło :
Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2021 Feb 13; Vol. 10 (1), pp. 22-26.
Typ publikacji :
Journal Article
MeSH Terms :
Gastric Lavage/*methods
Gastrointestinal Contents/*microbiology
Tuberculosis, Pulmonary/*diagnosis
Child, Preschool ; Female ; Haiti ; Humans ; Infant ; Infant, Newborn ; Male ; Mycobacterium tuberculosis ; Retrospective Studies ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
Pore-forming Esx proteins mediate toxin secretion by Mycobacterium tuberculosis.
Autorzy :
Tak U; Department of Microbiology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL, 35294, USA.
Dokland T; Department of Microbiology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL, 35294, USA.
Niederweis M; Department of Microbiology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL, 35294, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 15; Vol. 12 (1), pp. 394. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Bacterial Proteins/*metabolism
Bacterial Toxins/*metabolism
Mycobacterium tuberculosis/*pathogenicity
Porins/*metabolism
Type VII Secretion Systems/*metabolism
Amino Acid Motifs/genetics ; Bacterial Proteins/genetics ; Bacterial Toxins/toxicity ; Cell Membrane/metabolism ; Cell Membrane/ultrastructure ; Humans ; Lipid Bilayers/metabolism ; Microscopy, Electron ; Mutation ; Mycobacterium tuberculosis/metabolism ; Porins/genetics ; Protein Multimerization ; THP-1 Cells ; Tuberculosis/microbiology ; Tuberculosis/pathology ; Type VII Secretion Systems/genetics
Czasopismo naukowe
Tytuł :
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site.
Autorzy :
Mendes V; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK. .
Green SR; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, Scotland, UK.
Evans JC; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research & Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa.
Hess J; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Blaszczyk M; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
Spry C; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Bryant O; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
Cory-Wright J; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
Chan DS; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Torres PHM; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK.
Wang Z; Division of Infectious Diseases, Weill Department of Medicine, Weill Cornell Medical College, New York, NY, 10065, USA.
Nahiyaan N; Division of Infectious Diseases, Weill Department of Medicine, Weill Cornell Medical College, New York, NY, 10065, USA.
O'Neill S; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, Scotland, UK.
Damerow S; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, Scotland, UK.
Post J; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, Scotland, UK.
Bayliss T; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, Scotland, UK.
Lynch SL; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research & Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa.
Coyne AG; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Ray PC; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, Scotland, UK.
Abell C; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Rhee KY; Division of Infectious Diseases, Weill Department of Medicine, Weill Cornell Medical College, New York, NY, 10065, USA.
Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA.
Barry CE 3rd; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research & Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa.; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, 20892, USA.
Mizrahi V; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research & Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa.
Wyatt PG; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, Scotland, UK.
Blundell TL; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Jan 08; Vol. 12 (1), pp. 143. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antitubercular Agents/*pharmacology
Bacterial Proteins/*antagonists & inhibitors
Carboxy-Lyases/*antagonists & inhibitors
Mycobacterium smegmatis/*enzymology
Mycobacterium tuberculosis/*drug effects
Peptide Synthases/*antagonists & inhibitors
Allosteric Regulation/drug effects ; Allosteric Site/drug effects ; Antitubercular Agents/therapeutic use ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Bacterial Proteins/ultrastructure ; Carboxy-Lyases/genetics ; Carboxy-Lyases/metabolism ; Carboxy-Lyases/ultrastructure ; Coenzyme A/biosynthesis ; Crystallography, X-Ray ; Enzyme Assays ; Gene Knockdown Techniques ; High-Throughput Screening Assays ; Humans ; Microbial Sensitivity Tests ; Mycobacterium tuberculosis/enzymology ; Mycobacterium tuberculosis/genetics ; Peptide Synthases/genetics ; Peptide Synthases/metabolism ; Peptide Synthases/ultrastructure ; Tuberculosis/drug therapy ; Tuberculosis/microbiology
Czasopismo naukowe

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