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Wyszukujesz frazę ""tuberculosis"" wg kryterium: Temat


Tytuł:
Association between a single nucleotide polymorphism of the ALOX5 gene and susceptibility to multisystem tuberculosis in a Chinese Han population.
Autorzy:
Zhang J; Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, No.37, Guo Xue Alley, Chengdu, 610041, Sichuan Province, People's Republic of China; Intensive Care Unit, Deyang People's Hospital, No 173, North Taishan Road, Deyang, 618000, Sichuan Province, People's Republic of China.
Wang MG; Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, No.37, Guo Xue Alley, Chengdu, 610041, Sichuan Province, People's Republic of China.
He JQ; Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, No.37, Guo Xue Alley, Chengdu, 610041, Sichuan Province, People's Republic of China. Electronic address: jianqing_.
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Źródło:
Microbial pathogenesis [Microb Pathog] 2023 Oct; Vol. 183, pp. 106289. Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:
Journal Article
MeSH Terms:
East Asian People*/ethnology
East Asian People*/genetics
Genetic Predisposition to Disease*/ethnology
Genetic Predisposition to Disease*/genetics
Tuberculosis*/genetics
Tuberculosis*/metabolism
Humans ; Arachidonate 5-Lipoxygenase/genetics ; Case-Control Studies ; China ; Gene Frequency ; Genotype ; Polymorphism, Single Nucleotide ; Tuberculosis, Pulmonary/genetics
Czasopismo naukowe
Tytuł:
Up-regulation of inflammatory reactions by MPT32, a secreted protein of Mycobacterium tuberculosis in RAW264.7 macrophages.
Autorzy:
Kim HD; Department of Biological Science, SungKyunkwan University, Suwon, Republic of Korea.
Choi H; Department of Biological Science, SungKyunkwan University, Suwon, Republic of Korea.
Abekura F; Department of Biological Science, SungKyunkwan University, Suwon, Republic of Korea.
Park J; Department of Biological Science, SungKyunkwan University, Suwon, Republic of Korea.; Division of Zoonotic and Vector Borne Disease Research, Center for Infectious Disease Research, Korea National Institute of Health, Cheongju, Republic of Korea.
Cho SH; Division of Zoonotic and Vector Borne Disease Research, Center for Infectious Disease Research, Korea National Institute of Health, Cheongju, Republic of Korea.
Lee YC; Department of Medicinal Biotechnology, College of Health Sciences, Dong-A University, Busan, South Korea.
Kim CH; Department of Biological Science, SungKyunkwan University, Suwon, Republic of Korea.; Samsung Advanced Institute for Health Science and Technology (SAIHST), Suwon, Republic of Korea.
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Źródło:
Journal of cellular biochemistry [J Cell Biochem] 2023 Sep; Vol. 124 (9), pp. 1423-1434. Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mycobacterium tuberculosis*
Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
Animals ; Mice ; Cyclooxygenase 2/genetics ; Inflammation ; Macrophages ; Matrix Metalloproteinase 9 ; NF-kappa B ; Up-Regulation ; Tuberculosis/metabolism ; Tuberculosis/microbiology
Czasopismo naukowe
Tytuł:
Mechanobiology: How pathogens use mechanics to modulate host interactions.
Autorzy:
Viljoen A; Louvain Institute of Biomolecular Science and Technology, UCLouvain, Croix du Sud, 4-5, bte L7.07.07, B-1348 Louvain-la-Neuve, Belgium. Electronic address: .
Dufrêne YF; Louvain Institute of Biomolecular Science and Technology, UCLouvain, Croix du Sud, 4-5, bte L7.07.07, B-1348 Louvain-la-Neuve, Belgium. Electronic address: .
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Źródło:
Cell [Cell] 2023 Nov 09; Vol. 186 (23), pp. 4994-4995.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Biomechanical Phenomena*
Mycobacterium tuberculosis*/physiology
Humans ; Biophysics ; Tuberculosis/microbiology
Czasopismo naukowe
Tytuł:
Structure of an endogenous mycobacterial MCE lipid transporter.
Autorzy:
Chen J; Department of Cell Biology, New York University School of Medicine, New York, NY, USA.
Fruhauf A; Department of Cell Biology, New York University School of Medicine, New York, NY, USA.
Fan C; Department of Cell Biology, New York University School of Medicine, New York, NY, USA.
Ponce J; Proteomics Laboratory, Division of Advanced Research Technologies, New York University School of Medicine, New York, NY, USA.
Ueberheide B; Proteomics Laboratory, Division of Advanced Research Technologies, New York University School of Medicine, New York, NY, USA.; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA.; Department of Neurology, New York University School of Medicine, New York, NY, USA.
Bhabha G; Department of Cell Biology, New York University School of Medicine, New York, NY, USA. .
Ekiert DC; Department of Cell Biology, New York University School of Medicine, New York, NY, USA. .; Department of Microbiology, New York University School of Medicine, New York, NY, USA. .
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Źródło:
Nature [Nature] 2023 Aug; Vol. 620 (7973), pp. 445-452. Date of Electronic Publication: 2023 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Proteins*/chemistry
Bacterial Proteins*/metabolism
Bacterial Proteins*/ultrastructure
Cryoelectron Microscopy*
Lipids*
Membrane Transport Proteins*/chemistry
Membrane Transport Proteins*/metabolism
Membrane Transport Proteins*/ultrastructure
Mycobacterium tuberculosis*/chemistry
Mycobacterium tuberculosis*/metabolism
Mycobacterium tuberculosis*/ultrastructure
Virus Internalization*
Animals ; Tuberculosis/microbiology ; Virulence Factors/chemistry ; Virulence Factors/metabolism ; ATP-Binding Cassette Transporters/chemistry ; ATP-Binding Cassette Transporters/metabolism ; ATP-Binding Cassette Transporters/ultrastructure ; Periplasm/metabolism ; Protein Domains ; Hydrophobic and Hydrophilic Interactions ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/metabolism ; Multiprotein Complexes/ultrastructure
Czasopismo naukowe
Tytuł:
Impaired T-cell response to phytohemagglutinin (PHA) in tuberculosis patients is associated with high IL-6 plasma levels and normalizes early during anti-mycobacterial treatment.
Autorzy:
Vivekanandan MM; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Adankwah E; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.; Department of Medical Diagnostics, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.
Aniagyei W; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Acheampong I; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Minadzi D; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Yeboah A; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Arthur JF; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Lamptey M; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Abass MK; Agogo Presbyterian Hospital, Agogo, Ghana.
Kumbel F; St. Mathias Catholic Hospital, Yeji, Ghana.
Osei-Yeboah F; Atebubu District Hospital, Atebubu, Ghana.
Gawusu A; Sene West Health Directorate, Kwame Danso, Ghana.
Debrah LB; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Owusu DO; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Debrah A; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Mayatepek E; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Duesseldorf, University Children's Hospital, Heinrich-Heine University, Moorenstr. 5, 40225, Duesseldorf, Germany.
Seyfarth J; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Duesseldorf, University Children's Hospital, Heinrich-Heine University, Moorenstr. 5, 40225, Duesseldorf, Germany.
Phillips RO; Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.; School of Medicine and Dentistry, College of Health Sciences, KNUST, Kumasi, Ghana.
Jacobsen M; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Duesseldorf, University Children's Hospital, Heinrich-Heine University, Moorenstr. 5, 40225, Duesseldorf, Germany. .
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Źródło:
Infection [Infection] 2023 Aug; Vol. 51 (4), pp. 1013-1023. Date of Electronic Publication: 2023 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/blood
T-Lymphocytes*/immunology
Tuberculosis*/drug therapy
Humans ; Cytokines/metabolism ; Mycobacterium tuberculosis ; Phytohemagglutinins/pharmacology ; Interferon-gamma
Czasopismo naukowe
Tytuł:
Evaluation of the IP-10 mRNA release assay for diagnosis of TB in HIV-infected individuals.
Autorzy:
Tang Y; Department of Infection and Immunity, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yu Y; Department of Clinical Laboratory, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Wang Q; Department of Clinical Laboratory, The Eighth Affiliated Hospital, Xinjiang Medical University, Urumqi, China.
Wen Z; Department of Scientific Research, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Song R; Beijing Chest Hospital, Capital Medical University, Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Li Y; Department of Clinical Laboratory, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Zhou Y; Department of Infectious Diseases, Gansu Provincial Infectious Disease Hospital, Lanzhou, China.
Ma R; Department of Clinical Laboratory, The Eighth Affiliated Hospital, Xinjiang Medical University, Urumqi, China.
Jia H; Beijing Chest Hospital, Capital Medical University, Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Bai S; Department of Infectious Diseases, Gansu Provincial Infectious Disease Hospital, Lanzhou, China.
Abdulsalam H; Department of Infectious Diseases, The Eighth Affiliated Hospital, Xinjiang Medical University, Urumqi, China.
Du B; Beijing Chest Hospital, Capital Medical University, Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Sun Q; Beijing Chest Hospital, Capital Medical University, Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Xing A; Beijing Chest Hospital, Capital Medical University, Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Pan L; Beijing Chest Hospital, Capital Medical University, Beijing Key Laboratory for Drug Resistant Tuberculosis Research, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Wang J; Department of Geriatric Medicine, Gansu Province Hospital Rehabilitation Center, Lanzhou, China.
Song Y; Department of Thoracic Surgery, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
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Źródło:
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Jun 02; Vol. 13, pp. 1152665. Date of Electronic Publication: 2023 Jun 02 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV Infections*/complications
Tuberculosis*/diagnosis
Humans ; Biomarkers ; Chemokine CXCL10 ; Interferon-gamma Release Tests/methods ; Mycobacterium tuberculosis ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł:
The unique N-terminal region of Mycobacterium tuberculosis sigma factor A plays a dominant role in the essential function of this protein.
Autorzy:
Singha B; National Institute of Immunology, New Delhi, India; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Behera D; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.
Khan MZ; National Institute of Immunology, New Delhi, India.
Singh NK; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Sowpati DT; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Gopal B; Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India. Electronic address: .
Nandicoori VK; National Institute of Immunology, New Delhi, India; CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Mar; Vol. 299 (3), pp. 102933. Date of Electronic Publication: 2023 Jan 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sigma Factor*/genetics
Sigma Factor*/metabolism
Mycobacterium tuberculosis*/genetics
Mycobacterium tuberculosis*/metabolism
Microbial Viability*/genetics
Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
Animals ; Mice ; Transcriptome ; Tuberculosis/microbiology ; Sequence Deletion ; Gene Expression Regulation, Bacterial/genetics
Czasopismo naukowe
Tytuł:
Genome-wide tiled detection of circulating Mycobacterium tuberculosis cell-free DNA using Cas13.
Autorzy:
Thakku SG; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Lirette J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Murugesan K; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Chen J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Theron G; DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Banaei N; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Clinical Microbiology Laboratory, Stanford Health Care, Palo Alto, CA, USA.
Blainey PC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA.
Gomez J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Wong SY; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Hung DT; Broad Institute of MIT and Harvard, Cambridge, MA, USA. .; Department of Genetics, Harvard Medical School, Boston, MA, USA. .; Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA. .
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Źródło:
Nature communications [Nat Commun] 2023 Mar 31; Vol. 14 (1), pp. 1803. Date of Electronic Publication: 2023 Mar 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mycobacterium tuberculosis*/genetics
Cell-Free System ; DNA, Bacterial/analysis ; DNA, Bacterial/genetics ; Genome, Bacterial ; CRISPR-Cas Systems ; Humans ; Tuberculosis/diagnosis ; Tuberculosis/microbiology
Czasopismo naukowe
Tytuł:
Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis.
Autorzy:
Barelier S; CNRS, AFMB, Aix-Marseille University, France.
Avellan R; CNRS, LISM, IMM FR3479, Aix-Marseille University, France.
Gnawali GR; Department of Chemistry and Biochemistry, University of Missouri-St. Louis, MO, USA.
Fourquet P; INSERM, CNRS, Institut Paoli-Calmettes, CRCM, Marseille Protéomique, Aix-Marseille University, France.
Roig-Zamboni V; CNRS, AFMB, Aix-Marseille University, France.
Poncin I; CNRS, LISM, IMM FR3479, Aix-Marseille University, France.
Point V; CNRS, LISM, IMM FR3479, Aix-Marseille University, France.
Bourne Y; CNRS, AFMB, Aix-Marseille University, France.
Audebert S; INSERM, CNRS, Institut Paoli-Calmettes, CRCM, Marseille Protéomique, Aix-Marseille University, France.
Camoin L; INSERM, CNRS, Institut Paoli-Calmettes, CRCM, Marseille Protéomique, Aix-Marseille University, France.
Spilling CD; Department of Chemistry and Biochemistry, University of Missouri-St. Louis, MO, USA.
Canaan S; CNRS, LISM, IMM FR3479, Aix-Marseille University, France.
Cavalier JF; CNRS, LISM, IMM FR3479, Aix-Marseille University, France.
Sulzenbacher G; CNRS, AFMB, Aix-Marseille University, France.
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Źródło:
The FEBS journal [FEBS J] 2023 Mar; Vol. 290 (6), pp. 1563-1582. Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antitubercular Agents*/chemical synthesis
Antitubercular Agents*/pharmacology
Antitubercular Agents*/therapeutic use
Mycobacterium tuberculosis*/drug effects
Mycobacterium tuberculosis*/enzymology
Bacterial Proteins*/antagonists & inhibitors
Bacterial Proteins*/chemistry
Organophosphorus Compounds*/chemistry
Hydrolases*/antagonists & inhibitors
Hydrolases*/chemistry
Molecular Docking Simulation*
Humans ; Macrophages/microbiology ; Tuberculosis/drug therapy ; Crystallography, X-Ray ; Computer Simulation
Czasopismo naukowe
Tytuł:
Mycobacterium tuberculosis Requires the Outer Membrane Lipid Phthiocerol Dimycocerosate for Starvation-Induced Antibiotic Tolerance.
Autorzy:
Block AM; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Namugenyi SB; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Palani NP; University of Minnesota Genomics Center, University of Minnesota, Minneapolis, Minnesota, USA.
Brokaw AM; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Zhang L; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
Beckman KB; University of Minnesota Genomics Center, University of Minnesota, Minneapolis, Minnesota, USA.
Tischler AD; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.
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Źródło:
MSystems [mSystems] 2023 Feb 23; Vol. 8 (1), pp. e0069922. Date of Electronic Publication: 2023 Jan 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Membrane Lipids*/chemistry
Mycobacterium tuberculosis*/drug effects
Mycobacterium tuberculosis*/genetics
Drug Resistance, Bacterial*
Humans ; Tuberculosis
Czasopismo naukowe
Tytuł:
Discovery of 1-hydroxy-2-methylquinolin-4(1H)-one derivatives as new cytochrome bd oxidase inhibitors for tuberculosis therapy.
Autorzy:
Zhou Y; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, School of Pharmacy, Jinan University, 855 Xingye Avenue, Guangzhou, 510632, China.
Shao M; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, School of Pharmacy, Jinan University, 855 Xingye Avenue, Guangzhou, 510632, China.
Wang W; State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for Cell Responses, College of Life Sciences, Nankai University, Tianjin, 300071, China.
Cheung CY; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, 9054, New Zealand.
Wu Y; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, School of Pharmacy, Jinan University, 855 Xingye Avenue, Guangzhou, 510632, China.
Yu H; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, School of Pharmacy, Jinan University, 855 Xingye Avenue, Guangzhou, 510632, China.
Hu X; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, School of Pharmacy, Jinan University, 855 Xingye Avenue, Guangzhou, 510632, China.
Cook GM; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, 9054, New Zealand.
Gong H; State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for Cell Responses, College of Life Sciences, Nankai University, Tianjin, 300071, China. Electronic address: .
Lu X; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Discovery of Chinese Ministry of Education (MOE), Guangzhou City Key Laboratory of Precision Chemical Drug Development, School of Pharmacy, Jinan University, 855 Xingye Avenue, Guangzhou, 510632, China. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2023 Jan 05; Vol. 245 (Pt 1), pp. 114896. Date of Electronic Publication: 2022 Nov 04.
Typ publikacji:
Journal Article
MeSH Terms:
Antitubercular Agents*/chemistry
Antitubercular Agents*/pharmacology
Mycobacterium tuberculosis*/drug effects
Mycobacterium tuberculosis*/enzymology
Oxidoreductases*/antagonists & inhibitors
Cytochrome b Group*/antagonists & inhibitors
Cytochrome d Group*/antagonists & inhibitors
Humans ; Tuberculosis/drug therapy
Czasopismo naukowe
Tytuł:
Novel 4-aminoquinolines: Synthesis, inhibition of the Mycobacterium tuberculosis enoyl-acyl carrier protein reductase, antitubercular activity, SAR, and preclinical evaluation.
Autorzy:
Paz JD; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Denise de Moura Sperotto N; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Ramos AS; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Pissinate K; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
da Silva Rodrigues Junior V; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Abbadi BL; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Borsoi AF; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Rambo RS; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Corso Minotto AC; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
da Silva Dadda A; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Galina L; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Macchi Hopf FS; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Muniz MN; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Borges Martinelli LK; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Roth CD; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Madeira Silva RB; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Perelló MA; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
de Matos Czeczot A; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Neves CE; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Duarte LS; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Leyser M; Laboratório de Imunologia e Microbiologia, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Dias de Oliveira S; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Laboratório de Imunologia e Microbiologia, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Bizarro CV; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil.
Machado P; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil. Electronic address: .
Basso LA; Instituto Nacional de Ciência e Tecnologia em Tuberculose, Centro de Pesquisas em Biologia Molecular e Funcional, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Biologia Celular e Molecular, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Pontifícia Universidade Católica do Rio Grande do Sul, 90616-900, Porto Alegre, Rio Grande do Sul, Brazil. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2023 Jan 05; Vol. 245 (Pt 1), pp. 114908. Date of Electronic Publication: 2022 Nov 18.
Typ publikacji:
Journal Article
MeSH Terms:
Aminoquinolines*/chemical synthesis
Aminoquinolines*/pharmacology
Aminoquinolines*/therapeutic use
Antitubercular Agents*/chemical synthesis
Antitubercular Agents*/pharmacology
Antitubercular Agents*/therapeutic use
Mycobacterium tuberculosis*/drug effects
Mycobacterium tuberculosis*/enzymology
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases*/antagonists & inhibitors
Enzyme Inhibitors*/chemical synthesis
Enzyme Inhibitors*/pharmacology
Enzyme Inhibitors*/therapeutic use
Animals ; Mice ; Tuberculosis/drug therapy ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Doxycycline as a Potential MMP-1 Inhibitor for the Treatment of Spondylitis Tuberculosis: A Study in Rabbit Model.
Autorzy:
Siregar O; Department of Orthopaedics and Traumatology, Adam Malik General Hospital, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Lelo A; Department of Pharmacology and Therapeutics School of Medicine, Universitas Sumatera Utara, Indonesia.
Rahyussalim AJ; Department of Orthopaedics and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Ilyas S; Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, Indonesia.
Benny; Department of Orthopaedics and Traumatology, Adam Malik General Hospital, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Kurniawati T; Stem Cell and Tissue Engineering Cluster, IMERI Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.; Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
Augustinus Y; Department of Orthopaedics and Traumatology, Adam Malik General Hospital, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Hendra; Department of Orthopaedics and Traumatology, Adam Malik General Hospital, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Mandagi T; Department of Orthopaedics and Traumatology, Adam Malik General Hospital, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Zufar MLL; Medical graduate, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Fathurrahman I; Medical graduate, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
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Źródło:
BioMed research international [Biomed Res Int] 2023 Jan 27; Vol. 2023, pp. 7421325. Date of Electronic Publication: 2023 Jan 27 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Doxycycline*/pharmacology
Spondylitis*/drug therapy
Tuberculosis*/microbiology
Matrix Metalloproteinase Inhibitors*/pharmacology
Animals ; Humans ; Rabbits ; Matrix Metalloproteinase 1/metabolism ; Mycobacterium tuberculosis
Czasopismo naukowe
Tytuł:
Implementation of a mycobacterial CRISPRi platform in Mycobacterium abscessus and demonstration of the essentiality of ftsZ Mab .
Autorzy:
Gupta R; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, 6900 Lake Nona Blvd, FL, 32827, USA. Electronic address: .
Rohde KH; Division of Immunity and Pathogenesis, College of Medicine, Burnett School of Biomedical Sciences, University of Central Florida, 6900 Lake Nona Blvd, FL, 32827, USA. Electronic address: .
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Źródło:
Tuberculosis (Edinburgh, Scotland) [Tuberculosis (Edinb)] 2023 Jan; Vol. 138, pp. 102292. Date of Electronic Publication: 2022 Dec 02.
Typ publikacji:
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Mycobacterium abscessus*/genetics
Mycobacterium Infections, Nontuberculous*
Mycobacterium tuberculosis*/genetics
Humans ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Gene Expression ; Nontuberculous Mycobacteria/genetics ; Tuberculosis/microbiology
Raport
Tytuł:
Assessing the utility of the Xpert Mycobacterium tuberculosis/rifampin assay for analysis of bronchoalveolar lavage fluid in patients with suspected pulmonary tuberculosis.
Autorzy:
Bai W; Department of Clinical Laboratory Medicine, Wenzhou Central Hospital, Wenzhou, China.
Liu L; Department of Clinical Laboratory Medicine, Wenzhou Longwan First People's Hospital, Wenzhou, China.
Wu L; Department of Clinical Laboratory Medicine, Wenzhou Central Hospital, Wenzhou, China.
Chen S; Department of Blood Transfusion, People's Hospital of Pingyang County, Wenzhou, China.
Wu S; Department of Clinical Laboratory Medicine, Wenzhou Central Hospital, Wenzhou, China.
Wang Z; Department of Obstetrics and Gynecology, Wenzhou Central Hospital, Wenzhou, China.
Xu K; Department of Clinical Laboratory Medicine, Wenzhou Central Hospital, Wenzhou, China.
Chi Q; Department of Respiratory and Critical Care Medicine, Key Laboratory of precision medicine of Wenzhou, Wenzhou Central Hospital, Wenzhou, China.
Pan Y; Department of Clinical Laboratory Medicine, Key Laboratory of precision medicine of Wenzhou, Wenzhou Central Hospital, Wenzhou, China.
Xu X; Department of Clinical Laboratory Medicine, Key Laboratory of precision medicine of Wenzhou, Wenzhou Central Hospital, Wenzhou, China.
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Źródło:
Journal of clinical laboratory analysis [J Clin Lab Anal] 2022 Jan; Vol. 36 (1), pp. e24154. Date of Electronic Publication: 2021 Dec 01.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*/drug effects
Mycobacterium tuberculosis*/genetics
Drug Resistance, Multiple, Bacterial/*genetics
Molecular Typing/*methods
Tuberculosis, Pulmonary/*diagnosis
Adult ; Antibiotics, Antitubercular/pharmacology ; Bronchoalveolar Lavage Fluid/microbiology ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Rifampin/pharmacology ; Tuberculosis, Multidrug-Resistant/diagnosis ; Tuberculosis, Multidrug-Resistant/microbiology ; Tuberculosis, Pulmonary/microbiology
Czasopismo naukowe
Tytuł:
Long non-coding RNA SNHG16 silencing inhibits proliferation and inflammation in Mycobacterium tuberculosis-infected macrophages by targeting miR-140-5p expression.
Autorzy:
Sun W; Senior Department of Tuberculosis, The 8th Medical Center of Chinese People's Liberation Army General Hospital, Tuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Beijing 100091, China.
Zhang X; Senior Department of Tuberculosis, The 8th Medical Center of Chinese People's Liberation Army General Hospital, Tuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Beijing 100091, China.
He X; Senior Department of Tuberculosis, The 8th Medical Center of Chinese People's Liberation Army General Hospital, Tuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Beijing 100091, China.
Zhang J; Senior Department of Tuberculosis, The 8th Medical Center of Chinese People's Liberation Army General Hospital, Tuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Beijing 100091, China.
Wang X; Senior Department of Tuberculosis, The 8th Medical Center of Chinese People's Liberation Army General Hospital, Tuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Beijing 100091, China.
Lin W; Senior Department of Tuberculosis, The 8th Medical Center of Chinese People's Liberation Army General Hospital, Tuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Beijing 100091, China.
Wang X; Senior Department of Tuberculosis, The 8th Medical Center of Chinese People's Liberation Army General Hospital, Tuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Beijing 100091, China.
Wu X; Senior Department of Tuberculosis, The 8th Medical Center of Chinese People's Liberation Army General Hospital, Tuberculosis Prevention and Control Key Laboratory, Beijing Key Laboratory of New Techniques of Tuberculosis Diagnosis and Treatment, Beijing 100091, China. Electronic address: .
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Źródło:
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2022 Sep; Vol. 103, pp. 105325. Date of Electronic Publication: 2022 Jun 29.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
RNA, Long Noncoding*/genetics
Tuberculosis*/diagnosis
Tuberculosis*/genetics
Biomarkers ; Cell Proliferation/genetics ; Humans ; Inflammation/metabolism ; Macrophages/metabolism ; Mycobacterium tuberculosis
Czasopismo naukowe
Tytuł:
Toll-like receptor-mediated innate immune responses by recognition of the recombinant dormancy-associated Mycobacterium tuberculosis proteins Rv2659c and Rv1738.
Autorzy:
Saelee C; Faculty of Medical Technology, Department of Clinical Microbiology and Applied Technology, Mahidol University, Bangkok, Thailand.
Hanthamrongwit J; Faculty of Medical Technology, Department of Clinical Microbiology and Applied Technology, Mahidol University, Bangkok, Thailand.
Soe PT; Faculty of Medical Technology, Department of Clinical Microbiology and Applied Technology, Mahidol University, Bangkok, Thailand.; Department of Medical Laboratory Technology, University of Medical Technology, Mandalay, Myanmar.
Khaenam P; Faculty of Medical Technology, Center of Standardization and Product Validation, Mahidol University, Bangkok, Thailand.
Inthasin N; Faculty of Medicine Siriraj Hospital, Department of Immunology, Mahidol University, Bangkok, Thailand.
Ekpo P; Faculty of Medicine Siriraj Hospital, Department of Immunology, Mahidol University, Bangkok, Thailand.
Chootong P; Faculty of Medical Technology, Department of Clinical Microbiology and Applied Technology, Mahidol University, Bangkok, Thailand.
Leepiyasakulchai C; Faculty of Medical Technology, Department of Clinical Microbiology and Applied Technology, Mahidol University, Bangkok, Thailand.
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Źródło:
PloS one [PLoS One] 2022 Sep 01; Vol. 17 (9), pp. e0273517. Date of Electronic Publication: 2022 Sep 01 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Proteins*/genetics
Bacterial Proteins*/immunology
Immunity, Innate*/genetics
Mycobacterium tuberculosis*/immunology
Toll-Like Receptors*/genetics
Tuberculosis*/genetics
Humans ; Cytokines/metabolism ; Leukocytes, Mononuclear/metabolism ; Recombinant Proteins/genetics ; Toll-Like Receptor 2/metabolism ; Toll-Like Receptor 4/genetics ; Tuberculosis Vaccines
Czasopismo naukowe
Tytuł:
Call for special attention to the caregiver burden of patients with drug-resistant tuberculosis in low- and middle-income countries.
Autorzy:
Wu S; Department of Pulmonary Medicine and Tuberculosis, National Clinical Research Center for Infectious Diseases, the Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.
Zhang H; Department of Pulmonary Medicine and Tuberculosis, National Clinical Research Center for Infectious Diseases, the Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.
Wang Y; Department of Pulmonary Medicine and Tuberculosis, National Clinical Research Center for Infectious Diseases, the Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.
Wang J; Department of Pulmonary Medicine and Tuberculosis, National Clinical Research Center for Infectious Diseases, the Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.
Zhang P; Department of Pulmonary Medicine and Tuberculosis, National Clinical Research Center for Infectious Diseases, the Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.
Asakawa T; Institute of Neurology, National Clinical Research Center for Infectious Diseases, the Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.
Lin Y; Department of Pulmonary Medicine and Tuberculosis, National Clinical Research Center for Infectious Diseases, the Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.
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Źródło:
Bioscience trends [Biosci Trends] 2023 Nov 18; Vol. 17 (5), pp. 405-408. Date of Electronic Publication: 2023 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Extensively Drug-Resistant Tuberculosis*/drug therapy
Tuberculosis, Multidrug-Resistant*/drug therapy
Humans ; Caregiver Burden ; Developing Countries ; Quality of Life
Czasopismo naukowe
Tytuł:
Expanding the squaramide library as mycobacterial ATP synthase inhibitors: Innovative synthetic pathway and biological evaluation.
Autorzy:
Chasák J; Department of Organic Chemistry, Faculty of Science, Palacký University, 17. listopadu 12, 77146, Olomouc, Czech Republic.
Oorts L; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), S7, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
Dak M; Department of Organic Chemistry, Faculty of Science, Palacký University, 17. listopadu 12, 77146, Olomouc, Czech Republic.
Šlachtová V; Department of Organic Chemistry, Faculty of Science, Palacký University, 17. listopadu 12, 77146, Olomouc, Czech Republic.
Bazgier V; Department of Physical Chemistry, Faculty of Science, Palacký University, 17. listopadu 12, 771 46, Olomouc, Czech Republic.
Berka K; Department of Physical Chemistry, Faculty of Science, Palacký University, 17. listopadu 12, 771 46, Olomouc, Czech Republic.
De Vooght L; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), S7, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
Smiejkowska N; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), S7, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
Calster KV; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), S7, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
Van Moll L; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), S7, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
Cappoen D; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), S7, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
Cos P; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), S7, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
Brulíková L; Department of Organic Chemistry, Faculty of Science, Palacký University, 17. listopadu 12, 77146, Olomouc, Czech Republic. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Nov 15; Vol. 95, pp. 117504. Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mycobacterium tuberculosis*
Tuberculosis, Multidrug-Resistant*
Humans ; Adenosine Triphosphate/metabolism ; Antitubercular Agents/chemistry ; Mitochondrial Proton-Translocating ATPases/chemistry ; Mitochondrial Proton-Translocating ATPases/metabolism
Czasopismo naukowe
Tytuł:
Advanced drug delivery and therapeutic strategies for tuberculosis treatment.
Autorzy:
Nair A; Department of Pharmaceutics, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682 041, Kerala, India.
Greeny A; Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682 041, Kerala, India.
Nandan A; Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682 041, Kerala, India.
Sah RK; Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682 041, Kerala, India.
Jose A; Department of Pharmacology, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682 041, Kerala, India.
Dyawanapelly S; Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, 400019, India.
Junnuthula V; Drug Research Program, Faculty of Pharmacy, University of Helsinki, Viikinkaari 5 E, 00790, Helsinki, Finland. .
K V A; Department of Pharmacology, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682 041, Kerala, India. .
Sadanandan P; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi, 682 041, Kerala, India. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2023 Nov 09; Vol. 21 (1), pp. 414. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Nanotubes, Carbon*
Tuberculosis*/drug therapy
Mycobacterium tuberculosis*
Humans ; Antitubercular Agents/therapeutic use ; Antitubercular Agents/pharmacology ; Drug Delivery Systems ; Nanomedicine
Czasopismo naukowe

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