Temat: "urea" - OpacWWW - Prolib Integro

Skocz do pozycji: 1 1.

Tytuł :: Correlation between breath ammonia and blood urea nitrogen levels in chronic kidney disease and dialysis patients.
Autorzy :: Chen CC; Department of Biological Science and Technology, National Chiao Tung University, No. 1001, Ta Hsueh Rd., Hsinchu City 300, Taiwan. Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, No. 25, Ln. 442, Sec. 1, Jingguo Rd., Hsinchu City 300, Taiwan.
Hsieh JC
Chao CH
Yang WS
Cheng HT
Chan CK
Lu CJ
Meng HF
Zan HW; Pokaż więcej
Źródło :: Journal of breath research [J Breath Res] 2020 Apr 28; Vol. 14 (3), pp. 036002. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Blood Urea Nitrogen*
Renal Dialysis*
Ammonia/*analysis
Breath Tests/*methods
Renal Insufficiency, Chronic/*blood
Adult ; Breath Tests/instrumentation ; Female ; Humans ; Hydrogen-Ion Concentration ; Male ; Middle Aged ; ROC Curve ; Renal Insufficiency, Chronic/diagnosis ; Saliva/chemistry ; Urea/analysis
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: Performance and mechanism of urea hydrolysis in partial nitritation system based on SBR.
Autorzy :: Hu H; School of Environment and Energy, South China University of Technology, Guangzhou, 510006, China; The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, China.
Deng C; School of Environment and Energy, South China University of Technology, Guangzhou, 510006, China; The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, China.
Wang X; School of Environment and Energy, South China University of Technology, Guangzhou, 510006, China; The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, China. Electronic address: .
Chen Z; School of Environment and Energy, South China University of Technology, Guangzhou, 510006, China; The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, China; Hua an Biotech Co., Ltd., Foshan, 528300, China.
Zhong Z; School of Environment and Energy, South China University of Technology, Guangzhou, 510006, China; The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, China.
Wang R; School of Environment and Energy, South China University of Technology, Guangzhou, 510006, China; The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, China.; Pokaż więcej
Źródło :: Chemosphere [Chemosphere] 2020 Nov; Vol. 258, pp. 127228. Date of Electronic Publication: 2020 May 31.
Typ publikacji :: Journal Article
MeSH Terms :: Ammonia/*analysis
Bioreactors/*microbiology
Nitrites/*analysis
Urea/*analysis
Water Pollutants, Chemical/*analysis
Water Purification/*methods
Aerobiosis ; Ammonia/metabolism ; Bacteria/metabolism ; Hydrolysis ; Nitrites/metabolism ; Nitrogen/analysis ; Nitrogen/metabolism ; Oxidation-Reduction ; Urea/metabolism ; Waste Water/chemistry ; Water Pollutants, Chemical/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 3 3.

Tytuł :: [Genetic analysis and prenatal diagnosis for a Chinese pedigree affected with N-acetylglutamate synthase deficiency].
Autorzy :: Chen J; Prenatal Diagnosis Center, Jiangxi Provincial Maternal and Child Health Care Hospital, Nanchang, Jiangxi 330006, China. .
Yuan H
Xie K
Guo Z
Yang Y
Zou Y
Chen G
Liu Y; Pokaż więcej
Źródło :: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2020 Dec 10; Vol. 37 (12), pp. 1360-1363.
Typ publikacji :: Case Reports; Journal Article
MeSH Terms :: Genetic Testing*
Prenatal Diagnosis*
Urea Cycle Disorders, Inborn*/diagnosis
Urea Cycle Disorders, Inborn*/genetics
Amino-Acid N-Acetyltransferase/genetics ; China ; Female ; Humans ; Male ; Mutation/genetics ; Pedigree ; Pregnancy ; Whole Exome Sequencing
SCR Disease Name :: N-acetyl glutamate synthetase deficiency
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: N -monoarylacetothioureas as potent urease inhibitors: synthesis, SAR, and biological evaluation.
Autorzy :: Li WY; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Ni WW; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Ye YX; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, PR China.
Fang HL; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Pan XM; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
He JL; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Zhou TL; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Yi J; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Liu SS; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Zhou M; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.
Xiao ZP; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, PR China.
Zhu HL; National Demonstration Center for Experimental Chemistry Education, Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, Jishou University, Jishou, PR China.; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, PR China.; Pokaż więcej
Źródło :: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 404-413.
Typ publikacji :: Journal Article
MeSH Terms :: Helicobacter pylori/*drug effects
Urea/*pharmacology
Urease/*antagonists & inhibitors
Anti-Bacterial Agents ; Dose-Response Relationship, Drug ; Enzyme Inhibitors ; Helicobacter pylori/cytology ; Helicobacter pylori/enzymology ; Microbial Sensitivity Tests ; Molecular Structure ; Structure-Activity Relationship ; Urea/analogs & derivatives ; Urea/chemistry ; Urease/metabolism
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 5 5.

Tytuł :: Highly efficient adsorption behavior and mechanism of Urea-Fe 3 O 4 @LDH for triphenyl phosphate.
Autorzy :: Hao M; National Engineering Laboratory for Biomass Power Generation Equipment, School of Renewable Energy, North China Electric Power University, Beijing, 102206, China.
Gao P; National Engineering Laboratory for Biomass Power Generation Equipment, School of Renewable Energy, North China Electric Power University, Beijing, 102206, China.
Yang D; National Engineering Laboratory for Biomass Power Generation Equipment, School of Renewable Energy, North China Electric Power University, Beijing, 102206, China.
Chen X; National Engineering Laboratory for Biomass Power Generation Equipment, School of Renewable Energy, North China Electric Power University, Beijing, 102206, China.
Xiao F; National Engineering Laboratory for Biomass Power Generation Equipment, School of Renewable Energy, North China Electric Power University, Beijing, 102206, China. Electronic address: .
Yang S; National Engineering Laboratory for Biomass Power Generation Equipment, School of Renewable Energy, North China Electric Power University, Beijing, 102206, China. Electronic address: .; Pokaż więcej
Źródło :: Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2020 Dec; Vol. 267, pp. 114142. Date of Electronic Publication: 2020 Feb 14.
Typ publikacji :: Journal Article
MeSH Terms :: Flame Retardants*
Urea*
Adsorption ; Organophosphates
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 6 6.

Tytuł :: Randomized controlled trial of landiolol, a short-acting beta-1 adrenergic receptor blocker, illustrating changes in high-molecular weight adiponectin levels after elective percutaneous coronary intervention.
Autorzy :: Kiyokuni M; Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Konishi M; Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan. .
Saigusa Y; Department of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan.
Iwata K; Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Nakayama N; Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Komura N; Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Sugano T; Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Ishigami T; Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Ishikawa T; Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Yamanaka T; Department of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan.
Tamura K; Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Kimura K; Department of Medical Science and Cardiorenal Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.; Pokaż więcej
Źródło :: Heart and vessels [Heart Vessels] 2020 Nov; Vol. 35 (11), pp. 1510-1517. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :: Journal Article; Randomized Controlled Trial
MeSH Terms :: Percutaneous Coronary Intervention*/adverse effects
Adiponectin/*blood
Adrenergic beta-1 Receptor Antagonists/*administration & dosage
Angina, Stable/*therapy
Coronary Artery Disease/*therapy
Morpholines/*administration & dosage
Urea/*analogs & derivatives
Adrenergic beta-1 Receptor Antagonists/adverse effects ; Aged ; Aged, 80 and over ; Angina, Stable/blood ; Angina, Stable/diagnosis ; Biomarkers/blood ; Coronary Artery Disease/blood ; Coronary Artery Disease/diagnostic imaging ; Female ; Humans ; Japan ; Male ; Middle Aged ; Molecular Weight ; Morpholines/adverse effects ; Prospective Studies ; Time Factors ; Treatment Outcome ; Urea/administration & dosage ; Urea/adverse effects
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 7 7.

Tytuł :: Solvatochromism in urea/water and urea-derivative/water solutions.
Autorzy :: Civera C; Facultad de Farmacia, Departamento de Química en Ciencias Farmacéuticas, Universidad Complutense de Madrid, Spain. .
Del Valle JC
Elorza MA
Elorza B
Arias C
Díaz-Oliva C
Catalán J
García Blanco F; Pokaż więcej
Źródło :: Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2020 Nov 21; Vol. 22 (43), pp. 25165-25176. Date of Electronic Publication: 2020 Oct 30.
Typ publikacji :: Journal Article
MeSH Terms :: Protein Denaturation*
Solvents/*chemistry
Urea/*chemistry
Water/*chemistry
Hydrogen-Ion Concentration ; Urea/analogs & derivatives
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: Differences between Holstein dairy cows in renal clearance rate of urea affect milk urea concentration and the relationship between milk urea and urinary nitrogen excretion.
Autorzy :: Müller CBM; Institute of Nutritional Physiology 'Oskar Kellner', Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 1, 18196 Dummerstorf, Germany.
Görs S; Institute of Nutritional Physiology 'Oskar Kellner', Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 1, 18196 Dummerstorf, Germany.
Derno M; Institute of Nutritional Physiology 'Oskar Kellner', Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 1, 18196 Dummerstorf, Germany.
Tuchscherer A; Institute of Genetics and Biometry, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 1, 18196 Dummerstorf, Germany.
Wimmers K; Institute of Genome Biology, Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.
Zeyner A; Institute of Agricultural and Nutritional Sciences, Group Animal Nutrition, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Kuhla B; Institute of Nutritional Physiology 'Oskar Kellner', Leibniz Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 1, 18196 Dummerstorf, Germany. Electronic address: .; Pokaż więcej
Źródło :: The Science of the total environment [Sci Total Environ] 2021 Feb 10; Vol. 755 (Pt 2), pp. 143198. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji :: Journal Article
MeSH Terms :: Milk*/chemistry
Urea*/analysis
Animal Feed/analysis ; Animals ; Cattle ; Diet/veterinary ; Female ; Lactation ; Nitrogen/analysis ; Rumen
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 9 9.

Tytuł :: Evaluation of blood urea nitrogen concentration and anorexia as predictors of nonsurvival in client-owned rabbits evaluated at a veterinary referral center.
Autorzy :: Zoller G
Di Girolamo N
Huynh M; Pokaż więcej
Źródło :: Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 2019 Jul 15; Vol. 255 (2), pp. 200-204.
Typ publikacji :: Journal Article
MeSH Terms :: Urea*
Anorexia/*veterinary
Animals ; Blood Urea Nitrogen ; Rabbits ; Referral and Consultation ; Retrospective Studies ; Risk Factors
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: Urea-assisted ensiling process of wilted maize stover for profitable biomethane production.
Autorzy :: Cui X; College of Engineering (Key Laboratory for Clean Renewable Energy Utilization Technology, Ministry of Agriculture), China Agricultural University, Beijing 100083, PR China.
Sun H; College of Engineering (Key Laboratory for Clean Renewable Energy Utilization Technology, Ministry of Agriculture), China Agricultural University, Beijing 100083, PR China.
Wen X; College of Engineering (Key Laboratory for Clean Renewable Energy Utilization Technology, Ministry of Agriculture), China Agricultural University, Beijing 100083, PR China.
Sobhi M; College of Engineering (Key Laboratory for Clean Renewable Energy Utilization Technology, Ministry of Agriculture), China Agricultural University, Beijing 100083, PR China.
Guo J; College of Engineering (Key Laboratory for Clean Renewable Energy Utilization Technology, Ministry of Agriculture), China Agricultural University, Beijing 100083, PR China. Electronic address: .
Dong R; College of Engineering (Key Laboratory for Clean Renewable Energy Utilization Technology, Ministry of Agriculture), China Agricultural University, Beijing 100083, PR China; Yantai Institute, China Agricultural University, Yantai 264032, Shandong, PR China.; Pokaż więcej
Źródło :: The Science of the total environment [Sci Total Environ] 2021 Feb 25; Vol. 757, pp. 143751. Date of Electronic Publication: 2020 Nov 14.
Typ publikacji :: Journal Article
MeSH Terms :: Urea*
Zea mays*
Biofuels ; Fermentation ; Methane ; Silage/analysis
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 11 11.

Tytuł :: The long-term effects of using nitrite and urea on the enrichment of comammox bacteria.
Autorzy :: Zhao Y; Department of Environmental Engineering, Zhejiang University, Hangzhou, China.
Hu J; Department of Environmental Engineering, Zhejiang University, Hangzhou, China.
Yang W; Department of Environmental Engineering, Zhejiang University, Hangzhou, China.
Wang J; Department of Environmental Engineering, Zhejiang University, Hangzhou, China.
Jia Z; State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing, China.
Zheng P; Department of Environmental Engineering, Zhejiang University, Hangzhou, China; Zhejiang Province Key Laboratory for Water Pollution Control and Environmental Safety, Hangzhou, China.
Hu B; Department of Environmental Engineering, Zhejiang University, Hangzhou, China; Zhejiang Province Key Laboratory for Water Pollution Control and Environmental Safety, Hangzhou, China; Key Laboratory of Environment Remediation and Ecological Health, Ministry of Education, College of Environmental Resource Sciences, Zhejiang University, Hangzhou, China. Electronic address: .; Pokaż więcej
Źródło :: The Science of the total environment [Sci Total Environ] 2021 Feb 10; Vol. 755 (Pt 2), pp. 142580. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :: Journal Article
MeSH Terms :: Nitrites*
Urea*
Ammonia ; Archaea/genetics ; Bacteria/genetics ; Nitrification ; Oxidation-Reduction ; Phylogeny ; Soil Microbiology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 12 12.

Tytuł :: Predictive values of blood urea nitrogen/creatinine ratio and other routine blood parameters on disease severity and survival of COVID-19 patients.
Autorzy :: Ok F; Department of Urology, Siirt State Hospital, Siirt, Turkey.
Erdogan O; Department of Urology, Siirt State Hospital, Siirt, Turkey.
Durmus E; Department of Urology, Siirt State Hospital, Siirt, Turkey.
Carkci S; Department of Urology, Siirt State Hospital, Siirt, Turkey.
Canik A; Department of Biochemistry, Siirt State Hospital, Siirt, Turkey.; Pokaż więcej
Źródło :: Journal of medical virology [J Med Virol] 2021 Feb; Vol. 93 (2), pp. 786-793. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :: Journal Article
MeSH Terms :: Blood Urea Nitrogen*
COVID-19/*diagnosis
Creatinine/*blood
Adult ; Aged ; Aged, 80 and over ; COVID-19/blood ; COVID-19/mortality ; Female ; Humans ; Male ; Middle Aged ; Odds Ratio ; Predictive Value of Tests ; Prognosis ; Proportional Hazards Models ; ROC Curve ; Retrospective Studies ; Survival Analysis ; Turkey
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: Preparation of biochar as a coating material for biochar-coated urea.
Autorzy :: Jia Y; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China.
Hu Z; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China; Sino-Danish Center for Education and Research, Beijing 100190, China; Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. Electronic address: .
Mu J; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China; Sino-Danish Center for Education and Research, Beijing 100190, China.
Zhang W; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China; Sino-Danish Center for Education and Research, Beijing 100190, China.
Xie Z; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China.
Wang G; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China; Sino-Danish Center for Education and Research, Beijing 100190, China.; Pokaż więcej
Źródło :: The Science of the total environment [Sci Total Environ] 2020 Aug 20; Vol. 731, pp. 139063. Date of Electronic Publication: 2020 Apr 29.
Typ publikacji :: Journal Article
MeSH Terms :: Charcoal*
Urea*
Pyrolysis ; Soil ; Temperature
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Short communication: Genetic aspects of milk urea nitrogen and new indicators of nitrogen efficiency in dairy cows.
Autorzy :: Bobbo T; Department of Agronomy, Food, Natural resources, Animals and Environment (DAFNAE), University of Padova, 35020 Legnaro (PD), Italy.
Penasa M; Department of Agronomy, Food, Natural resources, Animals and Environment (DAFNAE), University of Padova, 35020 Legnaro (PD), Italy. Electronic address: .
Rossoni A; Italian Brown Cattle Breeders Association (ANARB), 37012 Bussolengo (VR), Italy.
Cassandro M; Department of Agronomy, Food, Natural resources, Animals and Environment (DAFNAE), University of Padova, 35020 Legnaro (PD), Italy.; Pokaż więcej
Źródło :: Journal of dairy science [J Dairy Sci] 2020 Oct; Vol. 103 (10), pp. 9207-9212. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :: Journal Article
MeSH Terms :: Cattle/*genetics
Cattle/*metabolism
Milk/*chemistry
Nitrogen/*metabolism
Urea/*metabolism
Animals ; Female ; Lactation/genetics ; Milk Proteins/metabolism ; Selective Breeding ; Urea/chemistry ; Whey Proteins/analysis
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 15 15.

Tytuł :: 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis.
Autorzy :: Codony S; Laboratori de Quı́mica Farmacèutica (Unitat Associada al CSIC), Departament de Farmacologia, Toxicologia i Quı́mica Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain.
Pujol E; Laboratori de Quı́mica Farmacèutica (Unitat Associada al CSIC), Departament de Farmacologia, Toxicologia i Quı́mica Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain.
Pizarro J; Pharmacology, Departament de Farmacologia, Toxicologia i Quı́mica Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, 28029 Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, 08950 Esplugues de Llobregat, Spain.
Feixas F; CompBioLab Group, Departament de Quı́mica and Institut de Quı́mica Computacional i Catàlisi (IQCC), Universitat de Girona, C/ Maria Aurèlia Capmany 69, 17003 Girona, Spain.
Valverde E; Laboratori de Quı́mica Farmacèutica (Unitat Associada al CSIC), Departament de Farmacologia, Toxicologia i Quı́mica Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain.
Loza MI; Drug Screening Platform/Biofarma Research Group, CIMUS Research Center, University of Santiago de Compostela (USC), 15782 Santiago de Compostela, Spain.
Brea JM; Drug Screening Platform/Biofarma Research Group, CIMUS Research Center, University of Santiago de Compostela (USC), 15782 Santiago de Compostela, Spain.
Saez E; Small Molecule Discovery Platform, Molecular Therapeutics Program, Center for Applied Medical Research (CIMA), University of Navarra, 31008 Pamplona, Spain.
Oyarzabal J; Small Molecule Discovery Platform, Molecular Therapeutics Program, Center for Applied Medical Research (CIMA), University of Navarra, 31008 Pamplona, Spain.
Pineda-Lucena A; Small Molecule Discovery Platform, Molecular Therapeutics Program, Center for Applied Medical Research (CIMA), University of Navarra, 31008 Pamplona, Spain.
Pérez B; Department of Pharmacology, Therapeutics and Toxicology, Institute of Neurosciences, Autonomous University of Barcelona, Bellaterra, 08193 Barcelona, Spain.
Pérez C; Institute of Medicinal Chemistry, Spanish National Research Council (CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.
Rodríguez-Franco MI; Institute of Medicinal Chemistry, Spanish National Research Council (CSIC), C/Juan de la Cierva 3, 28006 Madrid, Spain.
Leiva R; Laboratori de Quı́mica Farmacèutica (Unitat Associada al CSIC), Universitat de Barcelona, 08028 Barcelona, Spain.
Osuna S; CompBioLab Group, Departament de Quı́mica and Institut de Quı́mica Computacional i Catàlisi (IQCC), Universitat de Girona, C/ Maria Aurèlia Capmany 69, 17003 Girona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Spain.
Morisseau C; Department of Entomology and Nematology and Comprehensive Cancer Center, University of California, Davis, Davis, California 95616, United States.
Hammock BD; Department of Entomology and Nematology and Comprehensive Cancer Center, University of California, Davis, Davis, California 95616, United States.
Vázquez-Carrera M; Pharmacology, Departament de Farmacologia, Toxicologia i Quı́mica Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain.; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM)-Instituto de Salud Carlos III, 28029 Madrid, Spain.; Pediatric Research Institute-Hospital Sant Joan de Déu, 08950 Esplugues de Llobregat, Spain.
Vázquez S; Laboratori de Quı́mica Farmacèutica (Unitat Associada al CSIC), Departament de Farmacologia, Toxicologia i Quı́mica Terapèutica, Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain.; Pokaż więcej
Źródło :: Journal of medicinal chemistry [J Med Chem] 2020 Sep 10; Vol. 63 (17), pp. 9237-9257. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Enzyme Inhibitors/*therapeutic use
Epoxide Hydrolases/*antagonists & inhibitors
Pancreatitis/*drug therapy
Urea/*chemistry
Acute Disease ; Animals ; Binding Sites ; Catalytic Domain ; Cell Line ; Cell Survival/drug effects ; Disease Models, Animal ; Endoplasmic Reticulum Stress/drug effects ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacokinetics ; Enzyme Inhibitors/pharmacology ; Epoxide Hydrolases/metabolism ; Half-Life ; Humans ; Mice ; Microsomes/metabolism ; Molecular Dynamics Simulation ; Pancreatitis/chemically induced ; Pancreatitis/pathology ; Rats ; Solubility ; Structure-Activity Relationship ; Urea/metabolism ; Urea/pharmacology ; Urea/therapeutic use
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: Efficacy and safety of landiolol, an ultra-short-acting β1-selective antagonist, for treatment of sepsis-related tachyarrhythmia (J-Land 3S): a multicentre, open-label, randomised controlled trial.
Autorzy :: Kakihana Y; Department of Emergency and Intensive Care Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Nishida O; Department of Anesthesiology & Critical Care Medicine, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Taniguchi T; Intensive Care Unit, University Hospital, Kanazawa University, Kanazawa, Ishikawa, Japan.
Okajima M; Intensive Care Unit, University Hospital, Kanazawa University, Kanazawa, Ishikawa, Japan.
Morimatsu H; Department of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Okayama, Japan.
Ogura H; Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Yamada Y; Department of Anesthesiology and Pain Relief Center, The University of Tokyo Hospital, Tokyo, Japan.
Nagano T; Clinical Development Planning, Ono Pharmaceutical Co, Osaka, Japan.
Morishima E; Data Science, Ono Pharmaceutical Co, Osaka, Japan.
Matsuda N; Department of Emergency & Critical Care Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: .; Pokaż więcej
Corporate Authors :: J-Land 3S Study Group
Źródło :: The Lancet. Respiratory medicine [Lancet Respir Med] 2020 Sep; Vol. 8 (9), pp. 863-872. Date of Electronic Publication: 2020 Mar 31.
Typ publikacji :: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :: Adrenergic beta-1 Receptor Antagonists/*therapeutic use
Morpholines/*therapeutic use
Sepsis/*complications
Tachycardia/*drug therapy
Urea/*analogs & derivatives
Adrenergic beta-1 Receptor Antagonists/adverse effects ; Aged ; Female ; Humans ; Male ; Morpholines/adverse effects ; Tachycardia/etiology ; Treatment Outcome ; Urea/adverse effects ; Urea/therapeutic use
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: Diagnostic performance of initial blood urea nitrogen combined with D-dimer levels for predicting in-hospital mortality in COVID-19 patients.
Autorzy :: Cheng A; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hu L; Department of Health Management Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang Y; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Huang L; Department of Anesthesiology, Hanyang Branch, Wuhan Hospital of Traditional Chinese Medicine, Wuhan, China.
Zhao L; Department of Health Management Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhang C; Department of Health Management Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu X; Department of Health Management Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xu R; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu F; Department of Urology, Central Hospital of Shaoyang, University of South China, Hengyang, China.
Li J; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Ye D; Cancer Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wang T; Center for Biomedical Research, NHC Key Laboratory of Respiratory Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lv Y; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Health Management Centre, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
Liu Q; Department of Nephrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .; Pokaż więcej
Źródło :: International journal of antimicrobial agents [Int J Antimicrob Agents] 2020 Sep; Vol. 56 (3), pp. 106110. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :: Journal Article
MeSH Terms :: Blood Urea Nitrogen*
Betacoronavirus/*pathogenicity
Coronavirus Infections/*diagnosis
Coronavirus Infections/*mortality
Fibrin Fibrinogen Degradation Products/*metabolism
Pneumonia, Viral/*diagnosis
Pneumonia, Viral/*mortality
Aged ; Area Under Curve ; Biomarkers/blood ; COVID-19 ; Coronavirus Infections/blood ; Coronavirus Infections/virology ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/virology ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Risk ; SARS-CoV-2
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 18 18.

Tytuł :: Metal-organic frameworks derived magnetic porous carbon for magnetic solid phase extraction of benzoylurea insecticides from tea sample by Box-Behnken statistical design.
Autorzy :: Duo H; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Lu X; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China.
Nie X; Research Institute of Experiment and Detection of Xinjiang Oilfield Company, Karamay, Xinjiang 834000, PR China.
Wang L; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China.
Wang S; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China.
Liang X; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China. Electronic address: .
Guo Y; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, PR China. Electronic address: .; Pokaż więcej
Źródło :: Journal of chromatography. A [J Chromatogr A] 2020 Aug 30; Vol. 1626, pp. 461328. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :: Journal Article
MeSH Terms :: Insecticides/*analysis
Magnetite Nanoparticles/*chemistry
Metal-Organic Frameworks/*chemistry
Tea/*chemistry
Urea/*analysis
Adsorption ; Carbon/chemistry ; Chromatography, High Pressure Liquid/methods ; Chromatography, High Pressure Liquid/standards ; Ferric Compounds/chemistry ; Insecticides/isolation & purification ; Insecticides/standards ; Limit of Detection ; Porosity ; Reference Standards ; Solid Phase Extraction ; Spectrophotometry, Ultraviolet ; Tea/metabolism ; Urea/analogs & derivatives ; Urea/isolation & purification ; Urea/standards
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: Antinociceptive, reinforcing, and pruritic effects of the G-protein signalling-biased mu opioid receptor agonist PZM21 in non-human primates.
Autorzy :: Ding H; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Kiguchi N; Department of Pharmacology, Wakayama Medical University, Wakayama, Japan.
Perrey DA; Center for Drug Discovery, Research Triangle Institute, Research Triangle Park, NC, USA.
Nguyen T; Center for Drug Discovery, Research Triangle Institute, Research Triangle Park, NC, USA.
Czoty PW; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Hsu FC; Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Zhang Y; Center for Drug Discovery, Research Triangle Institute, Research Triangle Park, NC, USA. Electronic address: .
Ko MC; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC, USA; W.G. Hefner Veterans Affairs Medical Center, Salisbury, NC, USA. Electronic address: .; Pokaż więcej
Źródło :: British journal of anaesthesia [Br J Anaesth] 2020 Oct; Vol. 125 (4), pp. 596-604. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Reinforcement, Psychology*
Analgesics/*pharmacology
Pruritus/*chemically induced
Receptors, Opioid, mu/*agonists
Thiophenes/*pharmacology
Urea/*analogs & derivatives
Animals ; Dose-Response Relationship, Drug ; Female ; Macaca mulatta ; Male ; Urea/pharmacology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: Comparison of Landiolol and Digoxin as an Intravenous Drug for Controlling the Heart Rate in Patients with Atrial Fibrillation and Severely Depressed Left Ventricular Function.
Autorzy :: Shinohara M; Department of Cardiovascular Medicine, Toho University Faculty of Medicine.
Wada R; Department of Cardiovascular Medicine, Toho University Faculty of Medicine.
Yano K; Department of Cardiovascular Medicine, Toho University Faculty of Medicine.
Akitsu K; Department of Cardiovascular Medicine, Toho University Faculty of Medicine.
Koike H; Department of Cardiovascular Medicine, Toho University Faculty of Medicine.
Kinoshita T; Department of Cardiovascular Medicine, Toho University Faculty of Medicine.
Suzuki T; Department of Cardiovascular Medicine, Toho University Faculty of Medicine.
Fujino T; Department of Cardiovascular Medicine, Toho University Faculty of Medicine.
Ikeda T; Department of Cardiovascular Medicine, Toho University Faculty of Medicine.; Pokaż więcej
Źródło :: International heart journal [Int Heart J] 2020 Sep 29; Vol. 61 (5), pp. 944-950. Date of Electronic Publication: 2020 Sep 12.
Typ publikacji :: Comparative Study; Journal Article
MeSH Terms :: Heart Rate*
Anti-Arrhythmia Agents/*therapeutic use
Atrial Fibrillation/*drug therapy
Digoxin/*therapeutic use
Heart Failure/*physiopathology
Morpholines/*therapeutic use
Tachycardia/*drug therapy
Urea/*analogs & derivatives
Ventricular Dysfunction, Left/*physiopathology
Administration, Intravenous ; Aged ; Aged, 80 and over ; Atrial Fibrillation/etiology ; Atrial Fibrillation/physiopathology ; Blood Pressure ; Female ; Heart Failure/complications ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Severity of Illness Index ; Stroke Volume ; Tachycardia/etiology ; Tachycardia/physiopathology ; Treatment Outcome ; Urea/therapeutic use ; Ventricular Dysfunction, Left/complications
: Czasopismo naukowe

Szczegóły

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