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Tytuł:
Urokinase-Type Plasminogen Activator Receptor Regulates Prosurvival and Angiogenic Properties of Cardiac Mesenchymal Stromal Cells.
Autorzy:
Dergilev K; Institute of Experimental Cardiology Named after Academician V.N. Smirnov, Federal State Budgetary Institution National Medical Research Center of Cardiology Named after Academician E.I. Chazov, Ministry of Health of the Russian Federation, 121552 Moscow, Russia.
Tsokolaeva Z; Institute of Experimental Cardiology Named after Academician V.N. Smirnov, Federal State Budgetary Institution National Medical Research Center of Cardiology Named after Academician E.I. Chazov, Ministry of Health of the Russian Federation, 121552 Moscow, Russia.; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 107031 Moscow, Russia.
Goltseva Y; Institute of Experimental Cardiology Named after Academician V.N. Smirnov, Federal State Budgetary Institution National Medical Research Center of Cardiology Named after Academician E.I. Chazov, Ministry of Health of the Russian Federation, 121552 Moscow, Russia.
Beloglazova I; Institute of Experimental Cardiology Named after Academician V.N. Smirnov, Federal State Budgetary Institution National Medical Research Center of Cardiology Named after Academician E.I. Chazov, Ministry of Health of the Russian Federation, 121552 Moscow, Russia.
Ratner E; Institute of Experimental Cardiology Named after Academician V.N. Smirnov, Federal State Budgetary Institution National Medical Research Center of Cardiology Named after Academician E.I. Chazov, Ministry of Health of the Russian Federation, 121552 Moscow, Russia.
Parfyonova Y; Institute of Experimental Cardiology Named after Academician V.N. Smirnov, Federal State Budgetary Institution National Medical Research Center of Cardiology Named after Academician E.I. Chazov, Ministry of Health of the Russian Federation, 121552 Moscow, Russia.; Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Lomonosov Moscow State University, 119192 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 25; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 25.
Typ publikacji:
Journal Article
MeSH Terms:
Mesenchymal Stem Cells*/metabolism
Receptors, Urokinase Plasminogen Activator*/genetics
Receptors, Urokinase Plasminogen Activator*/metabolism
Myocardium*/cytology
Animals ; Mice ; Integrins ; Signal Transduction ; Urokinase-Type Plasminogen Activator/genetics ; Urokinase-Type Plasminogen Activator/metabolism
Czasopismo naukowe
Tytuł:
Targeted imaging of uPAR expression in vivo with cyclic AE105 variants.
Autorzy:
Leth JM; Finsen Laboratory, Copenhagen University Hospital - Rigshospitalet, 2200, Copenhagen N, Denmark.; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, 2200, Copenhagen N, Denmark.
Newcombe EA; Structural Biology and NMR Laboratory, Copenhagen N, Denmark.; REPIN, Copenhagen N, Denmark.; The Linderstrøm Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaloes Vej 5, 2200, Copenhagen N, Denmark.
Grønnemose AL; Finsen Laboratory, Copenhagen University Hospital - Rigshospitalet, 2200, Copenhagen N, Denmark.; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, 2200, Copenhagen N, Denmark.; Department of Biochemistry and Molecular Biology, University of Southern Denmark, 5230, Odense M, Denmark.
Jørgensen JT; Department of Clinical Physiology and Nuclear Medicine and Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet, Copenhagen N, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen N, Denmark.
Qvist K; Department of Clinical Physiology and Nuclear Medicine and Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet, Copenhagen N, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen N, Denmark.
Clausen AS; Department of Clinical Physiology and Nuclear Medicine and Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet, Copenhagen N, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen N, Denmark.
Knudsen LBS; Department of Clinical Physiology and Nuclear Medicine and Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet, Copenhagen N, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen N, Denmark.
Kjaer A; Department of Clinical Physiology and Nuclear Medicine and Cluster for Molecular Imaging, Copenhagen University Hospital - Rigshospitalet, Copenhagen N, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen N, Denmark.
Kragelund BB; Structural Biology and NMR Laboratory, Copenhagen N, Denmark.; REPIN, Copenhagen N, Denmark.; The Linderstrøm Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaloes Vej 5, 2200, Copenhagen N, Denmark.
Jørgensen TJD; Department of Biochemistry and Molecular Biology, University of Southern Denmark, 5230, Odense M, Denmark.
Ploug M; Finsen Laboratory, Copenhagen University Hospital - Rigshospitalet, 2200, Copenhagen N, Denmark. .; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, 2200, Copenhagen N, Denmark. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 11; Vol. 13 (1), pp. 17248. Date of Electronic Publication: 2023 Oct 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Urokinase Plasminogen Activator*/metabolism
Tomography, X-Ray Computed*
Humans ; Cell Line, Tumor ; Peptides/chemistry ; Positron-Emission Tomography/methods ; Urokinase-Type Plasminogen Activator
Czasopismo naukowe
Tytuł:
Macrophages and Urokinase Plasminogen Activator Receptor System in Multiple Myeloma: Case Series and Literature Review.
Autorzy:
Manzo P; Hematology and Transplant Center, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', 84131 Salerno, Italy.
Giudice V; Hematology and Transplant Center, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', 84131 Salerno, Italy.; Department of Medicine and Surgery, University of Salerno, 84081 Baronissi, Italy.
Napolitano F; Department of Translational Medical Sciences, University of Naples 'Federico II', 80138 Naples, Italy.
De Novellis D; Hematology and Transplant Center, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', 84131 Salerno, Italy.; Department of Medicine and Surgery, University of Salerno, 84081 Baronissi, Italy.
Serio B; Hematology and Transplant Center, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', 84131 Salerno, Italy.
Moscato P; Rheumatology Unit, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', 84131 Salerno, Italy.
Montuori N; Department of Translational Medical Sciences, University of Naples 'Federico II', 80138 Naples, Italy.
Selleri C; Hematology and Transplant Center, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', 84131 Salerno, Italy.; Department of Medicine and Surgery, University of Salerno, 84081 Baronissi, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 23; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 23.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Receptors, Urokinase Plasminogen Activator*/metabolism
Multiple Myeloma*/drug therapy
Humans ; Urokinase-Type Plasminogen Activator/metabolism ; Signal Transduction ; Macrophages/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Potential of uPAR, αvβ6 Integrin, and Tissue Factor as Targets for Molecular Imaging of Oral Squamous Cell Carcinoma: Evaluation of Nine Targets in Primary Tumors and Metastases by Immunohistochemistry.
Autorzy:
Lawaetz M; Department of Otolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.; Department of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
Christensen A; Department of Otolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.; Department of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
Juhl K; Department of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
Karnov K; Department of Otolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.; Department of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
Lelkaitis G; Department of Pathology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Kanstrup Fiehn AM; Department of Pathology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Kjaer A; Department of Clinical Physiology, Nuclear Medicine and PET and Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet & Department of Biomedical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
von Buchwald C; Department of Otolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 14; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Molecular Imaging*
Mouth Neoplasms*/diagnostic imaging
Squamous Cell Carcinoma of Head and Neck*/diagnostic imaging
Urokinase-Type Plasminogen Activator*/metabolism
Humans ; Immunohistochemistry ; Receptors, Urokinase Plasminogen Activator/metabolism ; Thromboplastin
Czasopismo naukowe
Tytuł:
uPAR (PLAUR) Marks Two Intra-Tumoral Subtypes of Glioblastoma: Insights from Single-Cell RNA Sequencing.
Autorzy:
He Y; Department of Clinical Physiology, Nuclear Medicine and PET & Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet, 2200 Copenhagen, Denmark.; Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Døssing KBV; Department of Clinical Physiology, Nuclear Medicine and PET & Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet, 2200 Copenhagen, Denmark.; Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
Rossing M; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Bagger FO; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.
Kjaer A; Department of Clinical Physiology, Nuclear Medicine and PET & Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet, 2200 Copenhagen, Denmark.; Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 07; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/metabolism
Receptors, Urokinase Plasminogen Activator*/genetics
Receptors, Urokinase Plasminogen Activator*/metabolism
Humans ; Sequence Analysis, RNA ; Signal Transduction ; Tumor Microenvironment/genetics ; Single-Cell Gene Expression Analysis ; Biomarkers, Tumor
Czasopismo naukowe
Tytuł:
Urokinase-type plasminogen activator receptor (uPAR) assessed by liquid biopsies and PET/CT for prognostication in head and neck cancer patients.
Autorzy:
Risør LM; Department of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Binderup T; Department of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Fosbøl MØ; Department of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Andersen KF; Department of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Loft A; Department of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Friborg J; Department of Clinical Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Kjaer A; Department of Clinical Physiology and Nuclear Medicine & Cluster for Molecular Imaging, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark. .; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark. .
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Źródło:
Scientific reports [Sci Rep] 2022 Nov 09; Vol. 12 (1), pp. 19126. Date of Electronic Publication: 2022 Nov 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Urokinase Plasminogen Activator*
Head and Neck Neoplasms*/diagnostic imaging
Humans ; Positron Emission Tomography Computed Tomography ; Squamous Cell Carcinoma of Head and Neck ; Tomography, X-Ray Computed ; Liquid Biopsy ; Urokinase-Type Plasminogen Activator
Czasopismo naukowe
Tytuł:
Ligand-Based Design of Selective Peptidomimetic uPA and TMPRSS2 Inhibitors with Arg Bioisosteres.
Autorzy:
Müller P; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudinger Weg 5, D-55128 Mainz, Germany.
Zimmer C; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudinger Weg 5, D-55128 Mainz, Germany.
Frey A; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudinger Weg 5, D-55128 Mainz, Germany.
Holzmann G; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudinger Weg 5, D-55128 Mainz, Germany.
Weldert AC; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudinger Weg 5, D-55128 Mainz, Germany.
Schirmeister T; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudinger Weg 5, D-55128 Mainz, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 23; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Peptidomimetics*/chemistry
Peptidomimetics*/pharmacology
Urokinase-Type Plasminogen Activator*/metabolism
Serine Proteinase Inhibitors*/chemistry
Serine Proteinase Inhibitors*/pharmacology
Ligands ; Peptide Hydrolases ; Trypsin ; Serine Endopeptidases
Czasopismo naukowe
Tytuł:
Role of Formyl Peptide Receptors and β-Arrestin-1 in suPAR Signal Transduction in Mouse Podocytes: Interactions with αVβ3-Integrin.
Autorzy:
Kim EY; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
Dryer SE; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.; Department of Biomedical Sciences, Tilman J. Fertitta Family College of Medicine, University of Houston, Houston, TX 77204, USA.
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Źródło:
Cells [Cells] 2024 Jan 17; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
beta-Arrestin 1*
Receptors, Formyl Peptide*
Receptors, Urokinase Plasminogen Activator*
Animals ; Mice ; Integrin beta3 ; Podocytes ; Reactive Oxygen Species ; Receptor for Advanced Glycation End Products ; Signal Transduction ; Integrin alpha5
Czasopismo naukowe
Tytuł:
Urokinase-type plasminogen activator receptor (uPAR) as a therapeutic target in cancer.
Autorzy:
Zhai BT; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China.
Tian H; Xi'an Hospital of Traditional Chinese Medicine, Xi'an, 710021, China.
Sun J; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China.
Zou JB; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China.
Zhang XF; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China.
Cheng JX; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China.
Shi YJ; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China.
Fan Y; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China.
Guo DY; State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an, 712046, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2022 Mar 18; Vol. 20 (1), pp. 135. Date of Electronic Publication: 2022 Mar 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Neoplasms*/therapy
Receptors, Urokinase Plasminogen Activator*/genetics
Receptors, Urokinase Plasminogen Activator*/metabolism
Humans ; Prognosis ; Signal Transduction ; Urokinase-Type Plasminogen Activator/genetics ; Urokinase-Type Plasminogen Activator/metabolism
Czasopismo naukowe
Tytuł:
Identification of a novel compound heterozygous mutation and a homozygous mutation of SLURP1 in Chinese families with Mal de Meleda.
Autorzy:
Wang T; Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, China.
Tang Z; Department of Dermatology, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Xiao T; Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, China.
Ren J; Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, China.
He S; Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, China.
Liu Y; Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, China.
Xiao S; Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, China. xiao_.
Wang X; Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, China. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 Jul 01; Vol. 16 (1), pp. 152. Date of Electronic Publication: 2023 Jul 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Ly*/genetics
East Asian People*
Keratoderma, Palmoplantar*/genetics
Urokinase-Type Plasminogen Activator*/genetics
Adult ; Female ; Humans ; Algorithms ; Mutation
Czasopismo naukowe
Tytuł:
A versatile engineered extracellular vesicle platform simultaneously targeting and eliminating senescent stromal cells and tumor cells to promote tumor regression.
Autorzy:
Gong L; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Chen Z; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Feng K; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Luo L; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Zhang J; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Yuan J; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Ren Y; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Wang Y; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. .
Zheng X; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. .
Li Q; Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. liqing_.
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Mar 11; Vol. 22 (1), pp. 105. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/drug therapy
Extracellular Vesicles*/metabolism
Humans ; Urokinase-Type Plasminogen Activator/genetics ; Urokinase-Type Plasminogen Activator/metabolism ; RNA, Small Interfering ; Stromal Cells/metabolism ; Doxorubicin/pharmacology ; Peptides ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Urokinase in the treatment of tuberculous pleurisy: a systematic review and meta-analysis.
Autorzy:
Jing W; Affiliated Hospital of Guilin Medical University, Guilin, China.
Weng R; Affiliated Hospital of Guilin Medical University, Guilin, China.
Lin P; Affiliated Hospital of Guilin Medical University, Guilin, China.
Luo M; Affiliated Hospital of Guilin Medical University, Guilin, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Feb 24; Vol. 24 (1), pp. 258. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
Tuberculosis, Pleural*/drug therapy
Pleural Effusion*/drug therapy
Humans ; Urokinase-Type Plasminogen Activator/therapeutic use ; Exudates and Transudates ; Drainage
Czasopismo naukowe
Tytuł:
A pilot investigation of the association between HIV-1 Vpr amino acid sequence diversity and the tryptophan-kynurenine pathway as a potential mechanism for neurocognitive impairment.
Autorzy:
Asia LK; Human Metabolomics, North-West University, Potchefstroom, South Africa.
Van Vuren EJ; Hypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.; South African Medical Research Council, Unit for Hypertension and Cardiovascular Disease, North-West University, Potchefstroom, South Africa.
Lindeque Z; Human Metabolomics, North-West University, Potchefstroom, South Africa.
Williams ME; Human Metabolomics, North-West University, Potchefstroom, South Africa. .
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Źródło:
Virology journal [Virol J] 2024 Feb 23; Vol. 21 (1), pp. 47. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*/genetics
HIV-1*/metabolism
HIV Infections*/complications
Gene Products, vpr*
HIV Seropositivity*
Humans ; Tryptophan/metabolism ; Kynurenine/metabolism ; Amino Acid Sequence ; Chromatography, Liquid ; Pilot Projects ; Receptors, Urokinase Plasminogen Activator ; Tandem Mass Spectrometry ; Inflammation
Czasopismo naukowe
Tytuł:
Single-cell transcriptome analysis reveals keratinocyte subpopulations contributing to psoriasis in corneum and granular layer.
Autorzy:
Zhao Q; First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu, China.; Department of Dermatology, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Wu Y; First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu, China.
Wu X; First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu, China.; Department of Dermatology, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Liu M; First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu, China.; Department of Dermatology, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Nan L; First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou, Gansu, China.; Department of Dermatology, Gansu Provincial Hospital, Lanzhou, Gansu, China.
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Źródło:
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) [Skin Res Technol] 2024 Feb; Vol. 30 (2), pp. e13572.
Typ publikacji:
Journal Article
MeSH Terms:
S100A12 Protein*/metabolism
Psoriasis*/genetics
Humans ; Single-Cell Gene Expression Analysis ; Keratinocytes/metabolism ; NLR Proteins/metabolism ; Antigens, Ly/metabolism ; Urokinase-Type Plasminogen Activator/metabolism
Czasopismo naukowe
Tytuł:
Inflammatory burden of adolescents with childhood maltreatment: results from baseline data of a school cohort.
Autorzy:
Qu G; Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Liu H; Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Ma S; Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Han T; Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Zhang H; Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Sun L; Fuyang Center for Disease Control and Prevention, No.19, Zhongnan Avenue, Fuyang, 236000, Anhui, China.
Qin Q; Ma'anshan Center for Disease Control and Prevention, No.849, Jiangdong Avenue, Ma'anshan, 243000, Anhui, China.
Chen M; Changfeng Center for Disease Control and Prevention, Changfeng, Anhui, China.
Sun Y; Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China. yhsun_ahmu_.; Chaohu Hospital, Anhui Medical University, Hefei, 238000, Anhui, China. yhsun_ahmu_.; Center for Evidence-Based Practice, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China. yhsun_ahmu_.
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Źródło:
European child & adolescent psychiatry [Eur Child Adolesc Psychiatry] 2024 Feb; Vol. 33 (2), pp. 539-548. Date of Electronic Publication: 2023 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*
Child Abuse*/psychology
Psychological Tests*
Self Report*
Male ; Adult ; Child ; Humans ; Adolescent ; Receptors, Urokinase Plasminogen Activator ; Surveys and Questionnaires ; Schools ; Inflammation
SCR Protocol:
Childhood Trauma Questionnaire
Czasopismo naukowe
Tytuł:
Soluble urokinase plasminogen activator receptor in vaginally collected amniotic fluid predicting fetal inflammatory response syndrome: a prospective cohort study.
Autorzy:
Gulbiniene V; Faculty of Medicine, Vilnius University, Vilnius, Lithuania. .
Dumalakiene I; Department of Immunology, State Research Institute Center of Innovative Medicine, Vilnius, Lithuania.
Balciuniene G; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Pilypiene I; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Narkeviciute I; Department of Immunology, State Research Institute Center of Innovative Medicine, Vilnius, Lithuania.
Novickij V; Department of Immunology, State Research Institute Center of Innovative Medicine, Vilnius, Lithuania.
Vysniauskis G; Department of Immunology, State Research Institute Center of Innovative Medicine, Vilnius, Lithuania.
Ramasauskaite D; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
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Źródło:
BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2024 Jan 10; Vol. 24 (1), pp. 54. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Chorioamnionitis*/diagnosis
Premature Birth*
Fetal Diseases*
Systemic Inflammatory Response Syndrome*
Infant, Newborn ; Pregnancy ; Humans ; Female ; Amniotic Fluid ; Prospective Studies ; Receptors, Urokinase Plasminogen Activator
SCR Disease Name:
fetal inflammatory response syndrome
Czasopismo naukowe
Tytuł:
The uPA/uPAR System Orchestrates the Inflammatory Response, Vascular Homeostasis, and Immune System in Fibrosis Progression.
Autorzy:
Kanno Y; Department of Clinical Pathological Biochemistry, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyoto 610-0395, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 16; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Urokinase-Type Plasminogen Activator*/metabolism
Inflammation*
Humans ; Fibrosis ; Immune System/metabolism ; Homeostasis
Czasopismo naukowe
Tytuł:
The Association of PLAUR Genotype and Soluble suPAR Serum Level with COVID-19-Related Lung Damage Severity.
Autorzy:
Nekrasova LA; Medical Scientific and Educational Centre, Lomonosov Moscow State University, 119192 Moscow, Russia.
Shmakova AA; Koltzov Institute of Developmental Biology, 117334 Moscow, Russia.
Samokhodskaya LM; Medical Scientific and Educational Centre, Lomonosov Moscow State University, 119192 Moscow, Russia.
Kirillova KI; Medical Scientific and Educational Centre, Lomonosov Moscow State University, 119192 Moscow, Russia.
Stoyanova SS; Medical Scientific and Educational Centre, Lomonosov Moscow State University, 119192 Moscow, Russia.
Mershina EA; Medical Scientific and Educational Centre, Lomonosov Moscow State University, 119192 Moscow, Russia.
Nazarova GB; Medical Scientific and Educational Centre, Lomonosov Moscow State University, 119192 Moscow, Russia.
Rubina KA; Faculty of Medicine, Lomonosov Moscow State University, 119192 Moscow, Russia.
Semina EV; Medical Scientific and Educational Centre, Lomonosov Moscow State University, 119192 Moscow, Russia.; Faculty of Medicine, Lomonosov Moscow State University, 119192 Moscow, Russia.; Institute of Experimental Cardiology, National Medical Research Centre of Cardiology Named after Academician E.I. Chazov, 121552 Moscow, Russia.
Kamalov AA; Medical Scientific and Educational Centre, Lomonosov Moscow State University, 119192 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 19; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 19.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/genetics
Lung*/pathology
Receptors, Urokinase Plasminogen Activator*/blood
Receptors, Urokinase Plasminogen Activator*/genetics
Adult ; Humans ; Genotype ; Retrospective Studies ; SARS-CoV-2
Czasopismo naukowe
Tytuł:
Prognostic value of soluble urokinase-type plasminogen activator receptor in coronary artery disease: A meta-analysis.
Autorzy:
Li Y; Emergency center, The First Affiliated Hospital of Army Medical University, Chongqing, China.
Ding Y; Emergency center, The First Affiliated Hospital of Army Medical University, Chongqing, China.
Zhao Y; Emergency center, The First Affiliated Hospital of Army Medical University, Chongqing, China.
Gui Y; Emergency center, The First Affiliated Hospital of Army Medical University, Chongqing, China.
Shen Y; Emergency center, The First Affiliated Hospital of Army Medical University, Chongqing, China.
Xiang Q; Emergency center, The First Affiliated Hospital of Army Medical University, Chongqing, China.
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Źródło:
European journal of clinical investigation [Eur J Clin Invest] 2022 Dec; Vol. 52 (12), pp. e13867. Date of Electronic Publication: 2022 Sep 08.
Typ publikacji:
Meta-Analysis; Journal Article
MeSH Terms:
Receptors, Urokinase Plasminogen Activator*
Coronary Artery Disease*
Humans ; Prognosis ; Biomarkers ; Proportional Hazards Models
Czasopismo naukowe
Tytuł:
Elevated expression of urokinase plasminogen activator in rodent models and patients with cerebral amyloid angiopathy.
Autorzy:
Vervuurt M; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands.
Zhu X; Department of Biomedical and Pharmaceutical Sciences, George & Anne Institute for Neuroscience, University of Rhode Island, Kingston, Rhode Island, USA.
Schrader J; Department of Biomedical and Pharmaceutical Sciences, George & Anne Institute for Neuroscience, University of Rhode Island, Kingston, Rhode Island, USA.
de Kort AM; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands.
Marques TM; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands.
Kersten I; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands.
Peters van Ton AM; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Abdo WF; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Schreuder FHBM; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands.
Rasing I; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Terwindt GM; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Wermer MJH; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Greenberg SM; Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Klijn CJM; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands.
Kuiperij HB; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands.
Van Nostrand WE; Department of Biomedical and Pharmaceutical Sciences, George & Anne Institute for Neuroscience, University of Rhode Island, Kingston, Rhode Island, USA.
Verbeek MM; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
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Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2022 Aug; Vol. 48 (5), pp. e12804. Date of Electronic Publication: 2022 Mar 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Cerebral Amyloid Angiopathy*/metabolism
Urokinase-Type Plasminogen Activator*/genetics
Urokinase-Type Plasminogen Activator*/metabolism
Amyloid beta-Peptides/metabolism ; Animals ; Brain/metabolism ; Humans ; RNA, Messenger/metabolism ; Rats ; Rodentia/genetics ; Rodentia/metabolism
Czasopismo naukowe

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