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Wyświetlanie 1-19 z 19
Tytuł:
Ten quick tips for building FAIR workflows.
Autorzy:
de Visser C; Medical BioSciences Department, Radboud University Medical Center, Nijmegen, the Netherlands.
Johansson LF; Genomics Coordination Center and Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Kulkarni P; Medical BioSciences Department, Radboud University Medical Center, Nijmegen, the Netherlands.; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.
Mei H; Sequencing Analysis Support Core, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands.
Neerincx P; Genomics Coordination Center and Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Joeri van der Velde K; Genomics Coordination Center and Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Horvatovich P; Department of Analytical Biochemistry, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, the Netherlands.
van Gool AJ; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.
Swertz MA; Genomics Coordination Center and Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Hoen PAC'; Medical BioSciences Department, Radboud University Medical Center, Nijmegen, the Netherlands.
Niehues A; Medical BioSciences Department, Radboud University Medical Center, Nijmegen, the Netherlands.; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 Sep 28; Vol. 19 (9), pp. e1011369. Date of Electronic Publication: 2023 Sep 28 (Print Publication: 2023).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
The GlycoPaSER Prototype as a Real-Time N-Glycopeptide Identification Tool Based on the PaSER Parallel Computing Platform.
Autorzy:
Armony G; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Brehmer S; Bruker Daltonics GmbH & Co. KG, 28359 Bremen, Germany.
Srikumar T; Bruker Daltonics GmbH & Co. KG, 28359 Bremen, Germany.
Pfennig L; Bruker Daltonics GmbH & Co. KG, 28359 Bremen, Germany.
Zijlstra F; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Trede D; Bruker Daltonics GmbH & Co. KG, 28359 Bremen, Germany.
Kruppa G; Bruker Daltonics GmbH & Co. KG, 28359 Bremen, Germany.
Lefeber DJ; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
van Gool AJ; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Wessels HJCT; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 26; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Search Engine*
Glycopeptides*/chemistry
Amino Acid Sequence ; Glycosylation ; Software ; Polysaccharides/chemistry
Czasopismo naukowe
Tytuł:
Primary Focal Segmental Glomerulosclerosis Plasmas Increase Lipid Droplet Formation and Perilipin-2 Expression in Human Podocytes.
Autorzy:
den Braanker DJW; Department of Nephrology, Radboud Institute for Health Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Maas RJH; Department of Nephrology, Radboud Institute for Health Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
van Mierlo G; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands.
Parr NMJ; Department of Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Bakker-van Bebber M; Department of Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Deegens JKJ; Department of Nephrology, Radboud Institute for Health Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Jansen PWTC; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands.
Gloerich J; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Willemsen B; Department of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Dijkman HB; Department of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
van Gool AJ; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Wetzels JFM; Department of Nephrology, Radboud Institute for Health Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Rinschen MM; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.; Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Vermeulen M; Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands.
Nijenhuis T; Department of Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
van der Vlag J; Department of Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 22; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 22.
Typ publikacji:
Journal Article
MeSH Terms:
Podocytes*/metabolism
Glomerulosclerosis, Focal Segmental*/metabolism
Humans ; Perilipin-2/genetics ; Perilipin-2/metabolism ; Lipid Droplets/metabolism ; Kidney Glomerulus/metabolism ; Biomarkers/metabolism
Czasopismo naukowe
Tytuł:
Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies.
Autorzy:
Niehues A; Center for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Geert Grooteplein Zuid 26-28, Nijmegen, 6525 GA, Netherlands.; Translational Metabolic Laboratory, Department Laboratory Medicine, Radboud university medical center, Geert Grooteplein Zuid 10, Nijmegen, 6525 GA, Netherlands.
Bizzarri D; Molecular Epidemiology, LUMC, Einthovenweg 20, Leiden, 2333 ZC, Netherlands.; Leiden Computational Biology Center, LUMC, Einthovenweg 20, Leiden, 2333 ZC, Netherlands.
Reinders MJT; Leiden Computational Biology Center, LUMC, Einthovenweg 20, Leiden, 2333 ZC, Netherlands.; Delft Bioinformatics Lab, TU Delft, Van Mourik Broekmanweg 6, Delft, 2628 XE, Netherlands.
Slagboom PE; Molecular Epidemiology, LUMC, Einthovenweg 20, Leiden, 2333 ZC, Netherlands.; Max Planck Institute for the Biology of Ageing, Cologne, Germany.
van Gool AJ; Translational Metabolic Laboratory, Department Laboratory Medicine, Radboud university medical center, Geert Grooteplein Zuid 10, Nijmegen, 6525 GA, Netherlands.
van den Akker EB; Molecular Epidemiology, LUMC, Einthovenweg 20, Leiden, 2333 ZC, Netherlands.; Leiden Computational Biology Center, LUMC, Einthovenweg 20, Leiden, 2333 ZC, Netherlands.; Delft Bioinformatics Lab, TU Delft, Van Mourik Broekmanweg 6, Delft, 2628 XE, Netherlands.
't Hoen PAC; Center for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Geert Grooteplein Zuid 26-28, Nijmegen, 6525 GA, Netherlands. .
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Corporate Authors:
BBMRI-NL BIOS consortium
BBMRI-NL Metabolomics consortium
Źródło:
BMC genomics [BMC Genomics] 2022 Jul 31; Vol. 23 (1), pp. 546. Date of Electronic Publication: 2022 Jul 31.
Typ publikacji:
Journal Article
MeSH Terms:
Metabolomics*
Phenotype
Czasopismo naukowe
Tytuł:
The funhouse mirror: the I in personalised healthcare.
Autorzy:
Vegter MW; Institute for Science in Society, Faculty of Science, Radboud University, PO Box 6751, 6503, GG, Nijmegen, The Netherlands. .; Department of Social Sciences, Wageningen University & Research, PO Box 8130, 6700, EW, Wageningen, The Netherlands. .
Zwart HAE; Erasmus School of Philosophy, Erasmus University Rotterdam, Rotterdam, The Netherlands.
van Gool AJ; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
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Źródło:
Life sciences, society and policy [Life Sci Soc Policy] 2021 Jan 05; Vol. 17 (1), pp. 1. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Delivery of Health Care*
Precision Medicine*
Health Facilities ; Humans
Czasopismo naukowe
Tytuł:
Quantitative multiplex profiling of the complement system to diagnose complement-mediated diseases.
Autorzy:
Willems E; Laboratory of Medical Immunology Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.; Radboud Center for Infectious Diseases Radboud University Medical Center Nijmegen The Netherlands.; Translational Metabolic Laboratory Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.
Lorés-Motta L; Department of Ophthalmology Donders Institute for Brain Cognition and Behaviour Radboud University Medical Center Nijmegen The Netherlands.
Zanichelli A; Department of Biomedical and Clinical Sciences Luigi Sacco ASST Fatebenefratelli Sacco University of Milan Milan Italy.
Suffritti C; Department of Biomedical and Clinical Sciences Luigi Sacco ASST Fatebenefratelli Sacco University of Milan Milan Italy.
van der Flier M; Laboratory of Medical Immunology Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.; Radboud Center for Infectious Diseases Radboud University Medical Center Nijmegen The Netherlands.; Department of Pediatrics University Medical Center Utrecht Utrecht The Netherlands.; Amalia Children's Hospital Radboud University Medical Center Nijmegen The Netherlands.
van der Molen RG; Laboratory of Medical Immunology Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.
Langereis JD; Laboratory of Medical Immunology Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.
van Drongelen J; Department of Obstetrics and Gynecology Radboud University Medical Center Nijmegen The Netherlands.
van den Heuvel LP; Translational Metabolic Laboratory Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.; Amalia Children's Hospital Radboud University Medical Center Nijmegen The Netherlands.
Volokhina E; Translational Metabolic Laboratory Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.; Amalia Children's Hospital Radboud University Medical Center Nijmegen The Netherlands.
van de Kar NC; Amalia Children's Hospital Radboud University Medical Center Nijmegen The Netherlands.
Keizer-Garritsen J; Translational Metabolic Laboratory Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.
Levin M; Department of Medicine Section for Paediatrics Imperial College London London UK.
Herberg JA; Department of Medicine Section for Paediatrics Imperial College London London UK.
Martinon-Torres F; Translational Pediatrics and Infectious Diseases Instituto de Investigación Sanitaria de Santiago Hospital Clínico Universitario de Santiago Santiago de Compostela Spain.
Wessels HJ; Translational Metabolic Laboratory Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.
de Breuk A; Department of Ophthalmology Donders Institute for Brain Cognition and Behaviour Radboud University Medical Center Nijmegen The Netherlands.
Fauser S; Department of Ophthalmology University Hospital Cologne Koln Germany.; F. Hoffmann - La Roche AG Basel Switzerland.
Hoyng CB; Department of Ophthalmology Donders Institute for Brain Cognition and Behaviour Radboud University Medical Center Nijmegen The Netherlands.
den Hollander AI; Department of Ophthalmology Donders Institute for Brain Cognition and Behaviour Radboud University Medical Center Nijmegen The Netherlands.
de Groot R; Laboratory of Medical Immunology Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.; Radboud Center for Infectious Diseases Radboud University Medical Center Nijmegen The Netherlands.
van Gool AJ; Translational Metabolic Laboratory Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.
Gloerich J; Translational Metabolic Laboratory Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.
de Jonge MI; Laboratory of Medical Immunology Department of Laboratory Medicine Radboud Institute for Molecular Life Sciences Radboud University Medical Center Nijmegen The Netherlands.; Radboud Center for Infectious Diseases Radboud University Medical Center Nijmegen The Netherlands.
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Źródło:
Clinical & translational immunology [Clin Transl Immunology] 2020 Dec 09; Vol. 9 (12), pp. e1225. Date of Electronic Publication: 2020 Dec 09 (Print Publication: 2020).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Plasma C-Peptide and Risk of Developing Type 2 Diabetes in the General Population.
Autorzy:
Sokooti S; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Kieneker LM; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Borst MH; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Muller Kobold A; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Kootstra-Ros JE; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Gloerich J; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
van Gool AJ; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Heerspink HJL; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
T Gansevoort R; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Dullaart RPF; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Bakker SJL; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
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Źródło:
Journal of clinical medicine [J Clin Med] 2020 Sep 17; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 17.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Inflammation biomarker discovery in Parkinson's disease and atypical parkinsonisms.
Autorzy:
Santaella A; Departments of Neurology, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.; Laboratory Medicine, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.; Parkinson Center Nijmegen, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Kuiperij HB; Departments of Neurology, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.; Laboratory Medicine, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
van Rumund A; Departments of Neurology, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Esselink RAJ; Departments of Neurology, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.; Parkinson Center Nijmegen, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
van Gool AJ; Laboratory Medicine, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Bloem BR; Departments of Neurology, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.; Parkinson Center Nijmegen, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Verbeek MM; Departments of Neurology, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. .; Laboratory Medicine, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. .; Parkinson Center Nijmegen, Radboud University Medical Center, and Donders Institute for Brain, Cognition and Behavior, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. .
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Źródło:
BMC neurology [BMC Neurol] 2020 Jan 17; Vol. 20 (1), pp. 26. Date of Electronic Publication: 2020 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers/*cerebrospinal fluid
Parkinsonian Disorders/*cerebrospinal fluid
Aged ; Cohort Studies ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Multiple System Atrophy/cerebrospinal fluid ; Multiple System Atrophy/diagnosis ; Parkinson Disease/cerebrospinal fluid ; Parkinson Disease/diagnosis ; Parkinsonian Disorders/diagnosis
Czasopismo naukowe
Tytuł:
Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans.
Autorzy:
Keulen DV; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.; Quorics B.V., Rotterdam, The Netherlands.; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.
Pouwer MG; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Emilsson V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Pharmaceutical Sciences, University of Iceland, Reykjavik, Iceland.
Matic LP; Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.
Pieterman EJ; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.
Hedin U; Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.
Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Jennings LL; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States.
Holmstrøm K; Bioneer A/S, Hørsholm, Denmark.
Nielsen BS; Bioneer A/S, Hørsholm, Denmark.
Pasterkamp G; Laboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
Lindeman JHN; Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands.
van Gool AJ; TNO- Microbiology & Systems Biology, Zeist, The Netherlands.
Sollewijn Gelpke MD; Molecular Profiling Consulting, London, United Kingdom.
Princen HMG; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.
Tempel D; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.; Quorics B.V., Rotterdam, The Netherlands.; SkylineDx B.V., Rotterdam, The Netherlands.
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Źródło:
PloS one [PLoS One] 2019 Aug 28; Vol. 14 (8), pp. e0221477. Date of Electronic Publication: 2019 Aug 28 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apolipoproteins E/*metabolism
Atherosclerosis/*pathology
Cholesterol Ester Transfer Proteins/*metabolism
Oncostatin M/*metabolism
Animals ; Atherosclerosis/blood ; Atherosclerosis/genetics ; Biomarkers/metabolism ; Coronary Disease/blood ; Coronary Disease/genetics ; Coronary Disease/mortality ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Female ; Humans ; Inflammation/pathology ; Interleukin-6/metabolism ; Leukemia Inhibitory Factor Receptor alpha Subunit/genetics ; Leukemia Inhibitory Factor Receptor alpha Subunit/metabolism ; Mice, Transgenic ; Monocytes/pathology ; Oncostatin M/blood ; Oncostatin M/genetics ; Oncostatin M Receptor beta Subunit/genetics ; Oncostatin M Receptor beta Subunit/metabolism ; Phenotype ; Plaque, Atherosclerotic/genetics ; Plaque, Atherosclerotic/pathology ; Probability ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Survival Analysis ; Vascular Cell Adhesion Molecule-1/metabolism
Czasopismo naukowe
Tytuł:
Qualitative evaluation of coronary atherosclerosis in a large cohort of young and middle-aged Dutch tissue donors implies that coronary thrombo-embolic manifestations are stochastic.
Autorzy:
Lindeman JH; Dept. of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Hulsbos L; Dept. of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
van den Bogaerdt AJ; Euro Heart Valve Bank, Beverwijk, The Netherlands.
Geerts M; Dept. of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.
van Gool AJ; TNO Metabolic Health Research, Leiden, The Netherlands.
Hamming JF; Dept. of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.
van Dijk RA; Dept. of Surgery, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Schaapherder AF; Dept. of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
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Źródło:
PloS one [PLoS One] 2018 Nov 27; Vol. 13 (11), pp. e0207943. Date of Electronic Publication: 2018 Nov 27 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Coronary Artery Disease/*pathology
Plaque, Atherosclerotic/*parasitology
Thromboembolism/*pathology
Adolescent ; Adult ; Aged ; Aortic Valve/transplantation ; Child ; Cohort Studies ; Coronary Artery Disease/mortality ; Female ; Humans ; Male ; Middle Aged ; Netherlands ; Plaque, Atherosclerotic/mortality ; Plaque, Atherosclerotic/pathology ; Stochastic Processes ; Thromboembolism/mortality ; Tissue Donors ; Young Adult
Czasopismo naukowe
Tytuł:
Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice.
Autorzy:
van Keulen D; Laboratory of Experimental Cardiology, University Medical Centre Utrecht, Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Haematology, University Medical Centre Utrecht, Utrecht, The Netherlands.; Quorics B.V, Rotterdam, The Netherlands.; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.
Pouwer MG; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Pasterkamp G; Laboratory of Experimental Cardiology, University Medical Centre Utrecht, Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Haematology, University Medical Centre Utrecht, Utrecht, The Netherlands.
van Gool AJ; TNO- Microbiology & Systems Biology, Zeist, The Netherlands.; Radboudumc, Nijmegen, The Netherlands.
Sollewijn Gelpke MD; Molecular Profiling Consulting, London, England.
Princen HMG; TNO-Metabolic Health Research, Gaubius Laboratory, Leiden, The Netherlands.
Tempel D; Laboratory of Experimental Cardiology, University Medical Centre Utrecht, Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Haematology, University Medical Centre Utrecht, Utrecht, The Netherlands.; Quorics B.V, Rotterdam, The Netherlands.
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Źródło:
PloS one [PLoS One] 2018 Oct 01; Vol. 13 (10), pp. e0204911. Date of Electronic Publication: 2018 Oct 01 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Signal Transduction*
Cholesterol Ester Transfer Proteins/*genetics
E-Selectin/*genetics
Endothelial Cells/*cytology
Interleukin-6/*genetics
Oncostatin M/*metabolism
Animals ; Cell Adhesion ; Cells, Cultured ; Chemokine CCL2/genetics ; E-Selectin/blood ; Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells ; Humans ; Intercellular Adhesion Molecule-1/genetics ; Mice ; STAT Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Integrated Chemometrics and Statistics to Drive Successful Proteomics Biomarker Discovery.
Autorzy:
Suppers A; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA Nijmegen, The Netherlands. .
van Gool AJ; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA Nijmegen, The Netherlands. .
Wessels HJCT; Translational Metabolic Laboratory, Department of Laboratory Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA Nijmegen, The Netherlands. .
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Źródło:
Proteomes [Proteomes] 2018 Apr 26; Vol. 6 (2). Date of Electronic Publication: 2018 Apr 26.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Tytuł:
Network signatures link hepatic effects of anti-diabetic interventions with systemic disease parameters.
Autorzy:
Kelder T; TNO, Research Group Microbiology & Systems Biology, Zeist, The Netherlands. .; Current address: EdgeLeap B.V, Utrecht, The Netherlands. .
Verschuren L; TNO, Research Group Microbiology & Systems Biology, Zeist, The Netherlands. .
van Ommen B; TNO, Research Group Microbiology & Systems Biology, Zeist, The Netherlands. .
van Gool AJ; TNO, Research Group Microbiology & Systems Biology, Zeist, The Netherlands. .; Department of Laboratory Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands. .; Faculty of Physics, Mathematics and Informatics, Radboud University Nijmegen, Nijmegen, The Netherlands. .
Radonjic M; TNO, Research Group Microbiology & Systems Biology, Zeist, The Netherlands. .; Current address: EdgeLeap B.V, Utrecht, The Netherlands. .
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Źródło:
BMC systems biology [BMC Syst Biol] 2014 Sep 11; Vol. 8, pp. 108. Date of Electronic Publication: 2014 Sep 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Progression*
Models, Biological*
Diabetes Mellitus, Type 2/*drug therapy
Liver/*metabolism
Signal Transduction/*physiology
Transcriptome/*genetics
Animals ; Diabetes Mellitus, Type 2/diet therapy ; Fenofibrate/pharmacology ; Hydrocarbons, Fluorinated/pharmacology ; Mice ; Mice, Knockout ; Receptors, LDL/genetics ; Signal Transduction/genetics ; Sulfonamides/pharmacology
Czasopismo naukowe
Tytuł:
Analysis of 953 human proteins from a mitochondrial HEK293 fraction by complexome profiling.
Autorzy:
Wessels HJ; Department of Laboratory Medicine, Laboratory of Genetic Endocrine and Metabolic Disorders, Radboud University Medical Centre, Nijmegen, The Netherlands. />Vogel RO
Lightowlers RN
Spelbrink JN
Rodenburg RJ
van den Heuvel LP
van Gool AJ
Gloerich J
Smeitink JA
Nijtmans LG
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Źródło:
PloS one [PLoS One] 2013 Jul 23; Vol. 8 (7), pp. e68340. Date of Electronic Publication: 2013 Jul 23 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mitochondria/*metabolism
Mitochondrial Proteins/*metabolism
Multiprotein Complexes/*metabolism
Proteome/*metabolism
Proteomics/*methods
Chromatography, Liquid ; Cluster Analysis ; Databases, Protein ; HEK293 Cells ; Humans ; Mass Spectrometry ; Mitochondrial Proteins/chemistry ; Protein Binding ; Protein Structure, Tertiary ; Ribosomal Proteins/metabolism ; Subcellular Fractions/metabolism
Czasopismo naukowe
Tytuł:
An integrated framework of personalized medicine: from individual genomes to participatory health care.
Autorzy:
Evers AW; Department of Medical Psychology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands. />Rovers MM
Kremer JA
Veltman JA
Schalken JA
Bloem BR
van Gool AJ
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Źródło:
Croatian medical journal [Croat Med J] 2012 Aug; Vol. 53 (4), pp. 301-3.
Typ publikacji:
Journal Article
MeSH Terms:
Advisory Committees*
Precision Medicine*
Cost-Benefit Analysis ; Databases, Genetic ; Humans ; Interdisciplinary Communication ; Models, Statistical ; Translational Research, Biomedical
Czasopismo naukowe
Tytuł:
Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Autorzy:
Yan G; The South China Center for Innovative Pharmaceuticals, Guangzhou, China. />Zhang G
Fang X
Zhang Y
Li C
Ling F
Cooper DN
Li Q
Li Y
van Gool AJ
Du H
Chen J
Chen R
Zhang P
Huang Z
Thompson JR
Meng Y
Bai Y
Wang J
Zhuo M
Wang T
Huang Y
Wei L
Li J
Wang Z
Hu H
Yang P
Le L
Stenson PD
Li B
Liu X
Ball EV
An N
Huang Q
Zhang Y
Fan W
Zhang X
Li Y
Wang W
Katze MG
Su B
Nielsen R
Yang H
Wang J
Wang X
Wang J
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Źródło:
Nature biotechnology [Nat Biotechnol] 2011 Oct 16; Vol. 29 (11), pp. 1019-23. Date of Electronic Publication: 2011 Oct 16.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genome*
Macaca fascicularis/*genetics
Macaca mulatta/*genetics
Animals ; Base Sequence ; Chromosome Aberrations ; Evolution, Molecular ; Humans ; Models, Animal ; Molecular Sequence Data ; Polymorphism, Genetic ; Sequence Analysis, DNA ; Species Specificity
Czasopismo naukowe
    Wyświetlanie 1-19 z 19

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