Autor: "van Ijcken WFJ" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Split Pool Ligation-based Single-cell Transcriptome sequencing (SPLiT-seq) data processing pipeline comparison.
Autorzy:: Kuijpers L; Department of Cell Biology, Erasmus University Medical Center Rotterdam (Erasmus MC), Wytemaweg 80, Rotterdam, 3015CN, The Netherlands. .
Hornung B; Center for Biomics, Erasmus University Medical Center Rotterdam (Erasmus MC), Rotterdam, The Netherlands.
van den Hout-van Vroonhoven MCGN; Center for Biomics, Erasmus University Medical Center Rotterdam (Erasmus MC), Rotterdam, The Netherlands.
van IJcken WFJ; Center for Biomics, Erasmus University Medical Center Rotterdam (Erasmus MC), Rotterdam, The Netherlands.
Grosveld F; Department of Cell Biology, Erasmus University Medical Center Rotterdam (Erasmus MC), Wytemaweg 80, Rotterdam, 3015CN, The Netherlands.
Mulugeta E; Department of Cell Biology, Erasmus University Medical Center Rotterdam (Erasmus MC), Wytemaweg 80, Rotterdam, 3015CN, The Netherlands. .; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2024 Apr 12; Vol. 25 (1), pp. 361. Date of Electronic Publication: 2024 Apr 12.
Typ publikacji:: Journal Article
MeSH Terms:: Transcriptome*
Computational Biology*
Data Analysis

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Skocz do pozycji: 2.

Tytuł:: Species-specific responses during Seoul orthohantavirus infection in human and rat lung microvascular endothelial cells.
Autorzy:: Noack D; Department of Viroscience, Erasmus University Medical Center, Rotterdam, the Netherlands.
van den Hout MCGN; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Center for Biomics, Erasmus University Medical Center, Rotterdam, the Netherlands.
Embregts CWE; Department of Viroscience, Erasmus University Medical Center, Rotterdam, the Netherlands.
van IJcken WFJ; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Center for Biomics, Erasmus University Medical Center, Rotterdam, the Netherlands.
Koopmans MPG; Department of Viroscience, Erasmus University Medical Center, Rotterdam, the Netherlands.
Rockx B; Department of Viroscience, Erasmus University Medical Center, Rotterdam, the Netherlands.; Pokaż więcej
Źródło:: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Mar 27; Vol. 18 (3), pp. e0012074. Date of Electronic Publication: 2024 Mar 27 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Seoul virus*/genetics
Hantavirus Infections*
Hemorrhagic Fever with Renal Syndrome*
Humans ; Rats ; Animals ; Endothelial Cells ; Seoul ; Lung ; Rodentia ; Antiviral Agents

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Skocz do pozycji: 3.

Tytuł:: Distinctive cell-free DNA methylation characterizes presymptomatic genetic frontotemporal dementia.
Autorzy:: Giannini LAA; Department of Neurology, Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Boers RG; Department of Developmental Biology, Erasmus Medical Center, Rotterdam, The Netherlands.
van der Ende EL; Department of Neurology, Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Clinical Chemistry, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
Poos JM; Department of Neurology, Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Jiskoot LC; Department of Neurology, Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Boers JB; Department of Developmental Biology, Erasmus Medical Center, Rotterdam, The Netherlands.
van IJcken WFJ; Erasmus Center for Biomics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Dopper EG; Department of Neurology, Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Pijnenburg YAL; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit, Amsterdam UMC location Vumc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.
Seelaar H; Department of Neurology, Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Meeter LH; Department of Neurology, Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
van Rooij JGJ; Department of Neurology, Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.
Scheper W; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Faculty of Science, Vrije Universiteit, Amsterdam, The Netherlands.; Department of Human Genetics, Vrije Universiteit, Amsterdam UMC location Vumc, Amsterdam, The Netherlands.
Gribnau J; Department of Developmental Biology, Erasmus Medical Center, Rotterdam, The Netherlands.
van Swieten JC; Department of Neurology, Alzheimer Center Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2024 Mar; Vol. 11 (3), pp. 744-756. Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:: Journal Article
MeSH Terms:: Frontotemporal Dementia*/pathology
Pick Disease of the Brain*/genetics
Cell-Free Nucleic Acids*/genetics
Humans ; C9orf72 Protein/genetics ; Cross-Sectional Studies ; DNA Methylation ; Mutation

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Skocz do pozycji: 4.

Tytuł:: Single-Cell RNA Sequencing of Donor-Reactive T Cells Reveals Role of Apoptosis in Donor-Specific Hyporesponsiveness of Kidney Transplant Recipients.
Autorzy:: van der List ACJ; Erasmus MC Transplant Institute, Department of Internal Medicine, University Medical Center, 3015 CN Rotterdam, The Netherlands.
Litjens NHR; Erasmus MC Transplant Institute, Department of Internal Medicine, University Medical Center, 3015 CN Rotterdam, The Netherlands.
Brouwer RWW; Erasmus MC Center for Biomics, University Medical Center, 3015 CN Rotterdam, The Netherlands.
Klepper M; Erasmus MC Transplant Institute, Department of Internal Medicine, University Medical Center, 3015 CN Rotterdam, The Netherlands.
den Dekker AT; Erasmus MC Center for Biomics, University Medical Center, 3015 CN Rotterdam, The Netherlands.
van Ijcken WFJ; Erasmus MC Center for Biomics, University Medical Center, 3015 CN Rotterdam, The Netherlands.
Betjes MGH; Erasmus MC Transplant Institute, Department of Internal Medicine, University Medical Center, 3015 CN Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 23; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:: Journal Article
MeSH Terms:: Kidney Transplantation*/adverse effects
Leukocytes, Mononuclear ; Receptors, Antigen, T-Cell ; Apoptosis ; Sequence Analysis, RNA

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Skocz do pozycji: 5.

Tytuł:: Liquid Biopsies for Colorectal Cancer and Advanced Adenoma Screening and Surveillance: What to Measure?
Autorzy:: Eikenboom EL; Department of Clinical Genetics, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.; Department of Gastroenterology & Hepatology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Wilting SM; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Deger T; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Srebniak MI; Department of Clinical Genetics, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Van Veghel-Plandsoen M; Department of Clinical Genetics, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Boers RG; Department of Developmental Biology, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.
Boers JB; Department of Developmental Biology, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.
van IJcken WFJ; Center for Biomics, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.
Gribnau JH; Department of Developmental Biology, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.
Atmodimedjo P; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Dubbink HJ; Department of Pathology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Martens JWM; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Spaander MCW; Department of Gastroenterology & Hepatology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.
Wagner A; Department of Clinical Genetics, Erasmus MC Cancer Institute, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: Cancers [Cancers (Basel)] 2023 Sep 17; Vol. 15 (18). Date of Electronic Publication: 2023 Sep 17.
Typ publikacji:: Journal Article

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na półce

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Skocz do pozycji: 6.

Tytuł:: Machine learning-based somatic variant calling in cell-free DNA of metastatic breast cancer patients using large NGS panels.
Autorzy:: Jongbloed EM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Jansen MPHM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
de Weerd V; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Helmijr JA; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Beaufort CM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Reinders MJT; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands.
van Marion R; Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
van IJcken WFJ; Erasmus Center for Biomics, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Sonke GS; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Konings IR; Department of Medical Oncology, Amsterdam UMC, location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Jager A; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Martens JWM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Wilting SM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Makrodimitris S; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands. .; Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jun 27; Vol. 13 (1), pp. 10424. Date of Electronic Publication: 2023 Jun 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Breast Neoplasms*/genetics
Cell-Free Nucleic Acids*/genetics
Humans ; Female ; Mutation ; Breast ; High-Throughput Nucleotide Sequencing ; Machine Learning

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Skocz do pozycji: 7.

Tytuł:: Identification of candidate enhancers controlling the transcriptome during the formation of interphalangeal joints.
Autorzy:: Nowosad K; Department of Cell Biology, Erasmus University Medical Center, 3015 CN, Rotterdam, The Netherlands.; Department of Biomedical Sciences, Laboratory of Molecular Genetics, Medical University of Lublin, Lublin, Poland.; The Postgraduate School of Molecular Medicine, Medical University of Warsaw, Warsaw, Poland.
Brouwer RWW; Department of Cell Biology, Erasmus University Medical Center, 3015 CN, Rotterdam, The Netherlands.; Center for Biomics-Genomics, Erasmus University Medical Center, 3015 CN, Rotterdam, The Netherlands.
Odrzywolski A; Department of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin, Poland.; Department of Human Genetics, KU Leuven, 3000, Leuven, Belgium.
Korporaal AL; Department of Cell Biology, Erasmus University Medical Center, 3015 CN, Rotterdam, The Netherlands.
Gielniewski B; Laboratory of Molecular Neurobiology, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
Wojtaś B; Laboratory of Sequencing, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland.
van IJcken WFJ; Department of Cell Biology, Erasmus University Medical Center, 3015 CN, Rotterdam, The Netherlands.; Center for Biomics-Genomics, Erasmus University Medical Center, 3015 CN, Rotterdam, The Netherlands.
Grosveld F; Department of Cell Biology, Erasmus University Medical Center, 3015 CN, Rotterdam, The Netherlands.
Huylebroeck D; Department of Cell Biology, Erasmus University Medical Center, 3015 CN, Rotterdam, The Netherlands.
Tylzanowski P; Department of Biomedical Sciences, Laboratory of Molecular Genetics, Medical University of Lublin, Lublin, Poland. .; Department of Development and Regeneration, Skeletal Biology and Engineering Research Center, KU Leuven, 3000, Leuven, Belgium. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jul 27; Vol. 12 (1), pp. 12835. Date of Electronic Publication: 2022 Jul 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Osteoarthritis*
Transcriptome*
Adaptor Proteins, Signal Transducing ; Extremities ; Humans ; Joints ; Regulatory Sequences, Nucleic Acid

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Skocz do pozycji: 8.

Tytuł:: CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue.
Autorzy:: van Riet J; Department of Urology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands.; Cancer Computational Biology Center, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands.; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands.
Saha C; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Strepis N; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Brouwer RWW; Center for Biomics, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Martens-Uzunova ES; Department of Urology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands.
van de Geer WS; Cancer Computational Biology Center, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands.; Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands.
Swagemakers SMA; Clinical Bioinformatics, Department of Pathology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Stubbs A; Clinical Bioinformatics, Department of Pathology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Halimi Y; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Voogd S; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Tanmoy AM; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.; Child Health Research Foundation, 23/2 SEL Huq Skypark, Block-B, Khilji Rd, Dhaka, 1207, Bangladesh.
Komor MA; Translational Gastrointestinal Oncology, Department of Pathology, Netherlands Cancer Institute, Amsterdam, Netherlands.; Oncoproteomics Laboratory, Department of Medical Oncology, VU University Medical Center, Amsterdam, Netherlands.
Hoogstrate Y; Department of Neurology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Janssen B; GenomeScan, Leiden, Netherlands.
Fijneman RJA; Translational Gastrointestinal Oncology, Department of Pathology, Netherlands Cancer Institute, Amsterdam, Netherlands.
Niknafs YS; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA.
Chinnaiyan AM; Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA.
van IJcken WFJ; Center for Biomics, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
van der Spek PJ; Clinical Bioinformatics, Department of Pathology, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands.
Jenster G; Department of Urology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands.
Louwen R; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, Netherlands. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2022 Apr 08; Vol. 5 (1), pp. 338. Date of Electronic Publication: 2022 Apr 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Clustered Regularly Interspaced Short Palindromic Repeats*/genetics
RNA, Small Untranslated*
Archaea/genetics ; Bacteria/genetics ; Genome, Human ; Humans ; Male

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Skocz do pozycji: 9.

Tytuł:: Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts.
Autorzy:: Heshusius S; Department of Hematopoiesis, Department of Blood Cell Research, Sanquin Research, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands.; Department of Cell Biology, Erasmus MC, P.O. box 2040, 3000 CA, Rotterdam, The Netherlands.
Grech L; Department of Applied Biomedical Science, Faculty of Health Sciences, Mater Dei Hospital, Msida, MSD2090, Malta.
Gillemans N; Department of Cell Biology, Erasmus MC, P.O. box 2040, 3000 CA, Rotterdam, The Netherlands.
Brouwer RWW; Center for Biomics, Erasmus MC, P.O. box 2040, 3000 CA, Rotterdam, The Netherlands.
den Dekker XT; Center for Biomics, Erasmus MC, P.O. box 2040, 3000 CA, Rotterdam, The Netherlands.
van IJcken WFJ; Center for Biomics, Erasmus MC, P.O. box 2040, 3000 CA, Rotterdam, The Netherlands.
Nota B; Department of Molecular and Cellular Hemostasis, Sanquin Research, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands.
Felice AE; Thalassaemia Testing and Haemoglobin Research Laboratory, University of Malta, and Thalassaemia Clinic, Mater Dei Hospital, Msida, MSD2090, Malta.
van Dijk TB; Department of Cell Biology, Erasmus MC, P.O. box 2040, 3000 CA, Rotterdam, The Netherlands.
von Lindern M; Department of Hematopoiesis, Department of Blood Cell Research, Sanquin Research, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands.; Department of Cell Biology, Erasmus MC, P.O. box 2040, 3000 CA, Rotterdam, The Netherlands.
Borg J; Department of Applied Biomedical Science, Faculty of Health Sciences, Mater Dei Hospital, Msida, MSD2090, Malta.
van den Akker E; Department of Hematopoiesis, Department of Blood Cell Research, Sanquin Research, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands.
Philipsen S; Department of Cell Biology, Erasmus MC, P.O. box 2040, 3000 CA, Rotterdam, The Netherlands. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 10; Vol. 12 (1), pp. 336. Date of Electronic Publication: 2022 Jan 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Epigenesis, Genetic*
Epigenome*
Epigenomics*
Haploinsufficiency*
Erythroblasts/*metabolism
Hemoglobinopathies/*genetics
Kruppel-Like Transcription Factors/*genetics
Cells, Cultured ; Chromatin Immunoprecipitation Sequencing ; Erythroblasts/pathology ; Erythropoiesis/genetics ; Fetal Hemoglobin/genetics ; Fetal Hemoglobin/metabolism ; Genetic Predisposition to Disease ; Hemoglobinopathies/blood ; Hemoglobinopathies/diagnosis ; Humans ; Kruppel-Like Transcription Factors/metabolism ; Malta ; Penetrance ; Phenotype ; Primary Cell Culture ; RNA-Seq

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Skocz do pozycji: 10.

Tytuł:: Genome-wide aberrant methylation in primary metastatic UM and their matched metastases.
Autorzy:: Smit KN; Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Boers R; Oncode Institute, Department of Developmental Biology, Erasmus MC, Rotterdam, The Netherlands.
Vaarwater J; Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Boers J; Oncode Institute, Department of Developmental Biology, Erasmus MC, Rotterdam, The Netherlands.
Brands T; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Mensink H; The Rotterdam Eye Hospital, Rotterdam, The Netherlands.
Verdijk RM; Department of Pathology, Section Ophthalmic Pathology, Erasmus MC, Rotterdam, The Netherlands.
van IJcken WFJ; Center for Biomics, Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
Gribnau J; Oncode Institute, Department of Developmental Biology, Erasmus MC, Rotterdam, The Netherlands.
de Klein A; Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands.
Kilic E; Department of Ophthalmology, Erasmus MC, Rotterdam, The Netherlands. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Jan 07; Vol. 12 (1), pp. 42. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Melanoma/*genetics
Melanoma/*metabolism
Neoplasm Metastasis/*genetics
Uveal Neoplasms/*genetics
Uveal Neoplasms/*metabolism
DNA Mutational Analysis ; Epigenesis, Genetic ; Gene Expression Regulation, Neoplastic ; Humans ; Methylation ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; RNA Splicing Factors/genetics ; RNA Splicing Factors/metabolism ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism ; Ubiquitin Thiolesterase/genetics ; Ubiquitin Thiolesterase/metabolism
SCR Disease Name:: Uveal melanoma

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Skocz do pozycji: 11.

Tytuł:: Multi-Omics Profiling in Marfan Syndrome: Further Insights into the Molecular Mechanisms Involved in Aortic Disease.
Autorzy:: Verhagen JMA; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
Burger J; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.; Department of Molecular Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
Bekkers JA; Department of Cardiothoracic Surgery, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
den Dekker AT; Center for Biomics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
von der Thüsen JH; Department of Pathology and Clinical Bioinformatics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
Zajec M; Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.; Department of Neurology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
Brüggenwirth HT; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
van der Sterre MLT; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
van den Born M; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
Luider TM; Department of Neurology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
van IJcken WFJ; Center for Biomics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
Wessels MW; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
Essers J; Department of Molecular Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.; Department of Vascular Surgery, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.; Department of Radiation Oncology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
Roos-Hesselink JW; Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
van der Pluijm I; Department of Molecular Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.; Department of Vascular Surgery, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
van de Laar IMBH; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
Brosens E; Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 31; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 31.
Typ publikacji:: Journal Article
MeSH Terms:: Genomics*
Aortic Diseases/*genetics
Marfan Syndrome/*genetics
Adult ; Animals ; Aorta/metabolism ; Aorta/pathology ; Aortic Diseases/pathology ; Cell Respiration ; Female ; Fibrillin-1/metabolism ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Male ; Marfan Syndrome/pathology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Signal Transduction ; Transforming Growth Factor beta/metabolism

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Skocz do pozycji: 12.

Tytuł:: The Somatic Mutation Paradigm in Congenital Malformations: Hirschsprung Disease as a Model.
Autorzy:: MacKenzie KC; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.
Garritsen R; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.
Chauhan RK; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.; Fluidigm Europe B.V., 1101 CM Amstelveen, The Netherlands.
Sribudiani Y; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Universitas of Padjadjaran, Bandung 45363, Indonesia.
de Graaf BM; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.
Rugenbrink T; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.
Brouwer R; Department of Cell Biology & Center for Biomics, Erasmus University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
van Ijcken WFJ; Department of Cell Biology & Center for Biomics, Erasmus University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
de Blaauw I; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.; Department of Paediatric Surgery, Amalia Children's Hospital, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Brooks AS; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.
Sloots CEJ; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.
Meeuwsen CJHM; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.
Wijnen RM; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.
Newgreen DF; Department of Cell Biology, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC 3052, Australia.
Burns AJ; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.; Department of Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.; Takeda Pharmaceuticals, Cambridge, MA 02139, USA.
Hofstra RMW; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.; Department of Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, UK.
Alves MM; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.
Brosens E; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 16; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 16.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Copy Number Variations*
Mutation*
Enteric Nervous System/*metabolism
Hirschsprung Disease/*genetics
Neural Crest/*metabolism
Child ; Child, Preschool ; Enteric Nervous System/pathology ; Female ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Hirschsprung Disease/diagnosis ; Hirschsprung Disease/pathology ; Humans ; Leukocytes, Mononuclear/metabolism ; Leukocytes, Mononuclear/pathology ; Male ; Neural Crest/pathology ; Sequence Analysis, DNA

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Skocz do pozycji: 13.

Tytuł:: High-throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by methylated DNA sequencing (MeD-seq) of LpnPI digested fragments.
Autorzy:: Deger T; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
Boers RG; Department of Developmental Biology, Erasmus Medical Center, Rotterdam, Netherlands.
de Weerd V; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
Angus L; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
van der Put MMJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
Boers JB; Department of Developmental Biology, Erasmus Medical Center, Rotterdam, Netherlands.
Azmani Z; Center for Biomics, Erasmus Medical Center, Rotterdam, Netherlands.
van IJcken WFJ; Center for Biomics, Erasmus Medical Center, Rotterdam, Netherlands.
Grünhagen DJ; Department of Oncologic Surgery, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
van Dessel LF; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
Lolkema MPJK; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
Verhoef C; Department of Oncologic Surgery, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
Sleijfer S; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
Martens JWM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands.
Gribnau J; Department of Developmental Biology, Erasmus Medical Center, Rotterdam, Netherlands.
Wilting SM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, Netherlands. .; Pokaż więcej
Źródło:: Clinical epigenetics [Clin Epigenetics] 2021 Oct 20; Vol. 13 (1), pp. 196. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji:: Journal Article
MeSH Terms:: Cell-Free Nucleic Acids/*analysis
DNA Methylation/*genetics
Cell-Free Nucleic Acids/genetics ; DNA Methylation/physiology ; Genome-Wide Association Study/methods ; Genome-Wide Association Study/statistics & numerical data ; Humans ; Liquid Biopsy/methods ; Liquid Biopsy/statistics & numerical data ; Sequence Analysis, DNA/methods ; Sequence Analysis, DNA/statistics & numerical data

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na półce

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Skocz do pozycji: 14.

Tytuł:: Genome wide DNA methylation analysis of alveolar capillary dysplasia lung tissue reveals aberrant methylation of genes involved in development including the FOXF1 locus.
Autorzy:: Slot E; Department of Paediatric Surgery, Erasmus MC - Sophia Children's Hospital Rotterdam, Rotterdam, Netherlands.; Department of Clinical Genetics, Rm Ee2089, Erasmus MC Rotterdam, Wytemaweg 80, 3015 CN, Rotterdam, Netherlands.
Boers R; Department of Developmental Biology, Oncode Institute, Erasmus MC Rotterdam, Rotterdam, Netherlands.
Boers J; Department of Developmental Biology, Oncode Institute, Erasmus MC Rotterdam, Rotterdam, Netherlands.
van IJcken WFJ; Center for Biomics, Erasmus University Medical Center, Erasmus MC, Rotterdam, Netherlands.; Department of Cell Biology, Erasmus University Medical Center, Erasmus MC, Rotterdam, Netherlands.
Tibboel D; Department of Paediatric Surgery, Erasmus MC - Sophia Children's Hospital Rotterdam, Rotterdam, Netherlands.
Gribnau J; Department of Developmental Biology, Oncode Institute, Erasmus MC Rotterdam, Rotterdam, Netherlands.
Rottier R; Department of Paediatric Surgery, Erasmus MC - Sophia Children's Hospital Rotterdam, Rotterdam, Netherlands.; Department of Cell Biology, Erasmus University Medical Center, Erasmus MC, Rotterdam, Netherlands.
de Klein A; Department of Clinical Genetics, Rm Ee2089, Erasmus MC Rotterdam, Wytemaweg 80, 3015 CN, Rotterdam, Netherlands. .; Pokaż więcej
Źródło:: Clinical epigenetics [Clin Epigenetics] 2021 Jul 29; Vol. 13 (1), pp. 148. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Forkhead Transcription Factors/*analysis
Lung/*abnormalities
Persistent Fetal Circulation Syndrome/*genetics
Pulmonary Alveoli/*abnormalities
DNA Methylation/genetics ; DNA Methylation/physiology ; Female ; Forkhead Transcription Factors/blood ; Genome-Wide Association Study/methods ; Humans ; Infant ; Infant, Newborn ; Lung/metabolism ; Male ; Persistent Fetal Circulation Syndrome/blood
SCR Disease Name:: Alveolar capillary dysplasia

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Skocz do pozycji: 15.

Tytuł:: Histological, immunohistochemical and transcriptomic characterization of human tracheoesophageal fistulas.
Autorzy:: Brosens E; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Felix JF; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.; Department of Pediatrics and Generation R Study Group, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Boerema-de Munck A; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
de Jong EM; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Lodder EM; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.; Department of Clinical and Experimental Cardiology, Heart Center, Academic Medical Center, Amsterdam, The Netherlands.
Swagemakers S; Department of Pathology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Clinical Bioinformatics, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Buscop-van Kempen M; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
de Krijger RR; Department of Pathology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.; Dept. of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
Wijnen RMH; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
van IJcken WFJ; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
van der Spek P; Department of Pathology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Clinical Bioinformatics, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
de Klein A; Department of Clinical Genetics, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Tibboel D; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Rottier RJ; Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.; Department of Cell Biology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Nov 17; Vol. 15 (11), pp. e0242167. Date of Electronic Publication: 2020 Nov 17 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Transcriptome*
Tracheoesophageal Fistula/*metabolism
Actin Cytoskeleton/genetics ; Actin Cytoskeleton/metabolism ; Adult ; Bone Morphogenetic Proteins/genetics ; Bone Morphogenetic Proteins/metabolism ; Esophagus/metabolism ; Esophagus/pathology ; Extracellular Matrix/genetics ; Extracellular Matrix/metabolism ; Female ; Fibrosis ; Humans ; Lung/metabolism ; Male ; Signal Transduction ; Trachea/metabolism ; Tracheoesophageal Fistula/genetics ; Tracheoesophageal Fistula/pathology

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na półce

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Skocz do pozycji: 16.

Tytuł:: Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation.
Autorzy:: Zhao M; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Kiernan CH; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Stairiker CJ; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Hope JL; Cancer Immunology and Tumor Microenvironment Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States of America.
Leon LG; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
van Meurs M; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Brouwers-Haspels I; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Boers R; Department of Developmental Biology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Boers J; Department of Developmental Biology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Gribnau J; Department of Developmental Biology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Oncode Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
van IJcken WFJ; Center for Biomics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Bindels EM; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Hoogenboezem RM; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Erkeland SJ; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Mueller YM; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Katsikis PD; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2020 Jun 24; Vol. 16 (6), pp. e1008555. Date of Electronic Publication: 2020 Jun 24 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes/*immunology
DNA Methylation/*immunology
Hepatocyte Nuclear Factor 1-alpha/*immunology
Lymphocytic Choriomeningitis/*immunology
Lymphocytic choriomeningitis virus/*immunology
Promoter Regions, Genetic/*immunology
Animals ; CD8-Positive T-Lymphocytes/pathology ; Hepatocyte Nuclear Factor 1-alpha/genetics ; Lymphocytic Choriomeningitis/genetics ; Lymphocytic Choriomeningitis/pathology ; Lymphocytic choriomeningitis virus/genetics ; Mice ; Mice, Transgenic ; Signal Transduction/genetics ; Signal Transduction/immunology

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Skocz do pozycji: 17.

Tytuł:: MicroRNA expression and DNA methylation profiles do not distinguish between primary and recurrent well-differentiated liposarcoma.
Autorzy:: Vos M; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.; Department of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Boers R; Department of Developmental Biology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Vriends ALM; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Boers J; Department of Developmental Biology, Erasmus University Medical Center, Rotterdam, the Netherlands.
van Kuijk PF; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
van Houdt WJ; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
van Leenders GJLH; Department of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Wagrodzki M; Department of Pathology, Maria Skłodowska-Curie Institute-Oncology Center, Warsaw, Poland.
van IJcken WFJ; Center for Biomics, Erasmus University Medical Center, Rotterdam, the Netherlands.
Gribnau J; Department of Developmental Biology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Grünhagen DJ; Department of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Verhoef C; Department of Surgical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Sleijfer S; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Wiemer EAC; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Jan 23; Vol. 15 (1), pp. e0228014. Date of Electronic Publication: 2020 Jan 23 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
DNA Methylation/*genetics
Liposarcoma/*genetics
MicroRNAs/*genetics
Neoplasm Recurrence, Local/*genetics
Adult ; Aged ; Cluster Analysis ; Female ; Genetic Heterogeneity ; Humans ; Male ; MicroRNAs/metabolism ; Middle Aged ; Principal Component Analysis

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Skocz do pozycji: 18.

Tytuł:: CREPT Promotes Melanoma Progression Through Accelerated Proliferation and Enhanced Migration by RhoA-Mediated Actin Filaments and Focal Adhesion Formation.
Autorzy:: Liu H; Laboratory of Experimental Oncology, Department of Pathology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Seynhaeve ALB; Laboratory of Experimental Oncology, Department of Pathology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Brouwer RWW; Center for Biomics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
van IJcken WFJ; Center for Biomics, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Yang L; State Key Laboratory of Membrane Biology, School of Medicine, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China.
Wang Y; State Key Laboratory of Membrane Biology, School of Medicine, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China.
Chang Z; State Key Laboratory of Membrane Biology, School of Medicine, National Engineering Laboratory for Anti-tumor Therapeutics, Tsinghua University, Beijing 100084, China.
Ten Hagen TLM; Laboratory of Experimental Oncology, Department of Pathology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: Cancers [Cancers (Basel)] 2019 Dec 20; Vol. 12 (1). Date of Electronic Publication: 2019 Dec 20.
Typ publikacji:: Journal Article

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na półce

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Skocz do pozycji: 19.

Tytuł:: Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome.
Autorzy:: Carrión VJ; Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Droevendaalsesteeg 10, 6708 PB Wageningen, Netherlands.; Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE Leiden, Netherlands.
Perez-Jaramillo J; Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Droevendaalsesteeg 10, 6708 PB Wageningen, Netherlands.; PECET, University of Antioquia, Medellín, Antioquia 050010, Colombia.
Cordovez V; Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Droevendaalsesteeg 10, 6708 PB Wageningen, Netherlands.; Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE Leiden, Netherlands.
Tracanna V; Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, Netherlands.
de Hollander M; Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Droevendaalsesteeg 10, 6708 PB Wageningen, Netherlands.
Ruiz-Buck D; Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Droevendaalsesteeg 10, 6708 PB Wageningen, Netherlands.
Mendes LW; Cell and Molecular Biology Laboratory, Center for Nuclear Energy in Agriculture (CENA), University of Sao Paulo (USP), Piracicaba, Brazil.
van Ijcken WFJ; Erasmus MC, University Medical Center Rotterdam, Department of Cell Biology, Center for Biomics, 3025 CN Rotterdam, Netherlands.
Gomez-Exposito R; Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Droevendaalsesteeg 10, 6708 PB Wageningen, Netherlands.; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, Netherlands.
Elsayed SS; Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE Leiden, Netherlands.
Mohanraju P; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, Netherlands.
Arifah A; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, Netherlands.
van der Oost J; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, Netherlands.
Paulson JN; Department of Biostatistics, Product Development, Genentech Inc., South San Francisco, CA 94080, USA.
Mendes R; Laboratory of Environmental Microbiology, Brazilian Agricultural Research Corporation, Embrapa Environment, Rodovia SP 340, Km 127.5, 13820-000 Jaguariúna, Brazil.
van Wezel GP; Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Droevendaalsesteeg 10, 6708 PB Wageningen, Netherlands.; Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE Leiden, Netherlands.
Medema MH; Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, Netherlands. .
Raaijmakers JM; Department of Microbial Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Droevendaalsesteeg 10, 6708 PB Wageningen, Netherlands. .; Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE Leiden, Netherlands.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2019 Nov 01; Vol. 366 (6465), pp. 606-612.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Microbiota*
Beta vulgaris/*microbiology
Endophytes/*physiology
Plant Diseases/*microbiology
Plant Roots/*microbiology
Rhizoctonia/*pathogenicity
Bacteria/classification ; Bacterial Physiological Phenomena ; Bacteroidetes/physiology ; Biodiversity ; Chitinases/genetics ; Disease Resistance ; Flavobacterium/physiology ; Genes, Bacterial ; Genome, Bacterial ; Metagenome ; Mutagenesis, Site-Directed ; Peptide Synthases/genetics ; Polyketide Synthases/genetics ; Soil Microbiology

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na półce

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Skocz do pozycji: 20.

Tytuł:: The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation.
Autorzy:: Cantú I; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
van de Werken HJG; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
Gillemans N; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
Stadhouders R; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
Heshusius S; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.; Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands.
Maas A; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
Esteghamat F; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
Ozgur Z; Center for Biomics, Erasmus MC, Rotterdam, The Netherlands.
van IJcken WFJ; Center for Biomics, Erasmus MC, Rotterdam, The Netherlands.
Grosveld F; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
von Lindern M; Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands.
Philipsen S; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.
van Dijk TB; Department of Cell Biology, Erasmus MC, Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Mar 28; Vol. 14 (3), pp. e0208659. Date of Electronic Publication: 2019 Mar 28 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anemia, Hemolytic/*genetics
Erythroid Cells/*cytology
Kruppel-Like Transcription Factors/*genetics
ran GTP-Binding Protein/*genetics
Amino Acid Substitution ; Animals ; Cell Differentiation ; Cells, Cultured ; Chromatin/metabolism ; Disease Models, Animal ; Embryo, Nonmammalian/metabolism ; Erythroid Cells/metabolism ; Erythropoiesis ; Female ; Gene Expression Regulation, Developmental ; Male ; Mice ; Sequence Analysis, RNA/methods ; ran GTP-Binding Protein/metabolism

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