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Tytuł :
MWA Versus RFA for Perivascular and Peribiliary CRLM: A Retrospective Patient- and Lesion-Based Analysis of Two Historical Cohorts.
Autorzy :
van Tilborg AA; Department of Radiology and Nuclear Medicine, VU University Medical Centre, De Boelelaan 1117, 1081, Amsterdam, The Netherlands. .
Scheffer HJ; Department of Radiology and Nuclear Medicine, VU University Medical Centre, De Boelelaan 1117, 1081, Amsterdam, The Netherlands.
de Jong MC; Department of Radiology and Nuclear Medicine, VU University Medical Centre, De Boelelaan 1117, 1081, Amsterdam, The Netherlands.
Vroomen LG; Department of Radiology and Nuclear Medicine, VU University Medical Centre, De Boelelaan 1117, 1081, Amsterdam, The Netherlands.
Nielsen K; Department of Surgical Oncology, VU University Medical Centre, Amsterdam, The Netherlands.
van Kuijk C; Department of Radiology and Nuclear Medicine, VU University Medical Centre, De Boelelaan 1117, 1081, Amsterdam, The Netherlands.
van den Tol PM; Department of Surgical Oncology, VU University Medical Centre, Amsterdam, The Netherlands.
Meijerink MR; Department of Radiology and Nuclear Medicine, VU University Medical Centre, De Boelelaan 1117, 1081, Amsterdam, The Netherlands.
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Źródło :
Cardiovascular and interventional radiology [Cardiovasc Intervent Radiol] 2016 Oct; Vol. 39 (10), pp. 1438-46. Date of Electronic Publication: 2016 Jul 07.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Catheter Ablation/*methods
Colorectal Neoplasms/*pathology
Colorectal Neoplasms/*surgery
Liver Neoplasms/*secondary
Liver Neoplasms/*surgery
Microwaves/*therapeutic use
Ablation Techniques/methods ; Adult ; Aged ; Aged, 80 and over ; Bile Ducts/pathology ; Bile Ducts/surgery ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Radiofrequency Ablation to Improve Survival After Conversion Chemotherapy for Colorectal Liver Metastases.
Autorzy :
Nielsen K; Department of Surgery, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
Scheffer HJ; Department of Radiology and Nuclear Medicine, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Volders JH; Department of Surgery, Gelderse Vallei Hospital, Postbus 9025, 6716 RP, Ede, The Netherlands.
van der Vorst MJ; Department of Medical Oncology, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.; Department of Medical Oncology, Rijnstate Hospital, Marga Klompélaan 6, 6836 TA, Arnhem, The Netherlands.
van Tilborg AA; Department of Radiology and Nuclear Medicine, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Comans EF; Department of Radiology and Nuclear Medicine, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
de Lange-de Klerk ES; Department of Epidemiology and Biostatistics, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Sietses C; Department of Surgery, Gelderse Vallei Hospital, Postbus 9025, 6716 RP, Ede, The Netherlands.
Meijer S; Department of Surgery, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Meijerink MR; Department of Radiology and Nuclear Medicine, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
van den Tol MP; Department of Surgery, VU University Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
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Źródło :
World journal of surgery [World J Surg] 2016 Aug; Vol. 40 (8), pp. 1951-8.
Typ publikacji :
Journal Article
MeSH Terms :
Catheter Ablation*
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Colorectal Neoplasms/*pathology
Liver Neoplasms/*secondary
Liver Neoplasms/*therapy
Adult ; Aged ; Bevacizumab/administration & dosage ; Capecitabine/administration & dosage ; Chemotherapy, Adjuvant ; Disease-Free Survival ; Female ; Hepatectomy ; Humans ; Liver Neoplasms/diagnostic imaging ; Male ; Middle Aged ; Neoadjuvant Therapy ; Neoplasm Recurrence, Local/pathology ; Organoplatinum Compounds/administration & dosage ; Oxaliplatin ; Survival Rate ; Tomography, X-Ray Computed ; Ultrasonography
Czasopismo naukowe
Tytuł :
Prognostic significance of highly sulfated chondroitin sulfates in ovarian cancer defined by the single chain antibody GD3A11.
Autorzy :
van der Steen SC; Department of Obstetrics and Gynaecology, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands; Department of Biochemistry, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address: .
van Tilborg AA; Department of Pathology, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
Vallen MJ; Department of Obstetrics and Gynaecology, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands; Department of Biochemistry, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
Bulten J; Department of Pathology, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
van Kuppevelt TH; Department of Biochemistry, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
Massuger LF; Department of Obstetrics and Gynaecology, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
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Źródło :
Gynecologic oncology [Gynecol Oncol] 2016 Mar; Vol. 140 (3), pp. 527-36. Date of Electronic Publication: 2015 Dec 28.
Typ publikacji :
Journal Article
MeSH Terms :
Antibody Specificity*
Carcinoma/*metabolism
Chondroitin Sulfates/*immunology
Chondroitin Sulfates/*metabolism
Epitopes/*metabolism
Ovarian Neoplasms/*metabolism
Ovarian Neoplasms/*pathology
Single-Chain Antibodies/*metabolism
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/immunology ; Biomarkers, Tumor/metabolism ; Carcinoma/genetics ; Carcinoma/pathology ; DNA Methylation ; DNA Mutational Analysis ; Disease-Free Survival ; Epitopes/immunology ; Extracellular Matrix/immunology ; Female ; Humans ; Membrane Glycoproteins/genetics ; Middle Aged ; Neoplasm Staging ; Ovarian Neoplasms/genetics ; Ovary/metabolism ; Phenotype ; Single-Chain Antibodies/immunology ; Sulfotransferases/genetics ; Survival Rate ; Young Adult
Czasopismo naukowe
Tytuł :
Colorectal liver metastatic disease: efficacy of irreversible electroporation--a single-arm phase II clinical trial (COLDFIRE-2 trial).
Autorzy :
Scheffer HJ; Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
Vroomen LG; Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
Nielsen K; Department of Surgery, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
van Tilborg AA; Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
Comans EF; Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
van Kuijk C; Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
van der Meijs BB; Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
van den Bergh J; Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
van den Tol PM; Department of Surgery, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
Meijerink MR; Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. .
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Źródło :
BMC cancer [BMC Cancer] 2015 Oct 24; Vol. 15, pp. 772. Date of Electronic Publication: 2015 Oct 24.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study
MeSH Terms :
Electroporation*
Ablation Techniques/*methods
Colorectal Neoplasms/*pathology
Liver Neoplasms/*secondary
Liver Neoplasms/*surgery
Aged ; Female ; Fluorodeoxyglucose F18 ; Humans ; Male ; Middle Aged ; Survival Analysis ; Tomography, X-Ray Computed/methods
Czasopismo naukowe
Tytuł :
Irreversible Electroporation for Colorectal Liver Metastases.
Autorzy :
Scheffer HJ; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands.
Melenhorst MC; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands.
Echenique AM; Department of Radiology, Division of Vascular/Interventional Radiology, Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida.
Nielsen K; Department of Surgery, VU University Medical Center, Amsterdam, the Netherlands.
van Tilborg AA; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands.
van den Bos W; Department of Urology, Academic Medical Center, Amsterdam, the Netherlands.
Vroomen LG; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands.
van den Tol PM; Department of Surgery, VU University Medical Center, Amsterdam, the Netherlands.
Meijerink MR; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands. Electronic address: .
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Źródło :
Techniques in vascular and interventional radiology [Tech Vasc Interv Radiol] 2015 Sep; Vol. 18 (3), pp. 159-69. Date of Electronic Publication: 2015 Jun 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Ablation Techniques*/adverse effects
Ablation Techniques*/instrumentation
Colorectal Neoplasms/*pathology
Electroporation/*methods
Liver Neoplasms/*surgery
Surgery, Computer-Assisted/*methods
Cell Death ; Electroporation/instrumentation ; Equipment Design ; Humans ; Liver Neoplasms/secondary ; Positron-Emission Tomography ; Postoperative Complications/etiology ; Risk Factors ; Surgery, Computer-Assisted/adverse effects ; Surgery, Computer-Assisted/instrumentation ; Tomography, X-Ray Computed ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Percutaneous Irreversible Electroporation of a Large Centrally Located Hepatocellular Adenoma in a Woman with a Pregnancy Wish.
Autorzy :
Scheffer HJ; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands, .
Melenhorst MC
van Tilborg AA
Nielsen K
van Nieuwkerk KM
de Vries RA
van den Tol PM
Meijerink MR
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Źródło :
Cardiovascular and interventional radiology [Cardiovasc Intervent Radiol] 2015 Aug; Vol. 38 (4), pp. 1031-5. Date of Electronic Publication: 2014 Dec 24.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Electroporation*
Adenoma, Liver Cell/*therapy
Liver Neoplasms/*therapy
Adult ; Female ; Humans ; Liver/diagnostic imaging ; Pregnancy ; Radiography, Interventional ; Tomography, X-Ray Computed ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Percutaneous irreversible electroporation of locally advanced pancreatic carcinoma using the dorsal approach: a case report.
Autorzy :
Scheffer HJ; Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands, .
Melenhorst MC
Vogel JA
van Tilborg AA
Nielsen K
Kazemier G
Meijerink MR
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Źródło :
Cardiovascular and interventional radiology [Cardiovasc Intervent Radiol] 2015 Jun; Vol. 38 (3), pp. 760-5. Date of Electronic Publication: 2014 Oct 07.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Adenocarcinoma/*therapy
Catheter Ablation/*methods
Electroporation/*methods
Pancreatic Neoplasms/*therapy
Aged ; Humans ; Male ; Pancreas/diagnostic imaging ; Pancreatic Neoplasms/diagnostic imaging ; Radiography, Interventional ; Tomography, X-Ray Computed ; Treatment Outcome
SCR Disease Name :
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł :
Immunohistochemical and genetic profiles of endometrioid endometrial carcinoma arising from atrophic endometrium.
Autorzy :
Geels YP; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands.
van der Putten LJ; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: .
van Tilborg AA; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.
Lurkin I; Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.
Zwarthoff EC; Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.
Pijnenborg JM; Department of Obstetrics and Gynecology, TweeSteden Hospital, Tilburg, The Netherlands.
van den Berg-van Erp SH; Department of Pathology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Snijders MP; Department of Obstetrics and Gynecology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Bulten J; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.
Visscher DW; Department of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA.
Dowdy SC; Division of Gynecologic Surgery, Mayo Clinic, Rochester, MN, USA.
Massuger LF; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands.
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Źródło :
Gynecologic oncology [Gynecol Oncol] 2015 May; Vol. 137 (2), pp. 245-51. Date of Electronic Publication: 2015 Mar 12.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Endometrioid/*genetics
Carcinoma, Endometrioid/*metabolism
Endometrial Neoplasms/*genetics
Endometrial Neoplasms/*metabolism
Endometrium/*pathology
Atrophy ; Carcinoma, Endometrioid/pathology ; Carcinoma, Endometrioid/surgery ; Cohort Studies ; DNA Mutational Analysis ; Endometrial Hyperplasia/pathology ; Endometrial Neoplasms/pathology ; Endometrial Neoplasms/surgery ; Female ; Humans ; Immunohistochemistry
Czasopismo naukowe
Tytuł :
Transcatheter CT hepatic arteriography-guided percutaneous ablation to treat ablation site recurrences of colorectal liver metastases: the incomplete ring sign.
Autorzy :
van Tilborg AA; Departments of Radiology and Nuclear Medicine. Electronic address: .
Scheffer HJ; Departments of Radiology and Nuclear Medicine.
van der Meijs BB; Departments of Radiology and Nuclear Medicine.
van Werkum MH; Departments of Radiology and Nuclear Medicine.
Melenhorst MC; Departments of Radiology and Nuclear Medicine.
van den Tol PM; Surgical Oncology, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.
Meijerink MR; Departments of Radiology and Nuclear Medicine.
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Źródło :
Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2015 Apr; Vol. 26 (4), pp. 583-7.e1.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Catheter Ablation/*methods
Colorectal Neoplasms/*diagnostic imaging
Liver Neoplasms/*secondary
Liver Neoplasms/*surgery
Neoplasm Recurrence, Local/*surgery
Tomography, X-Ray Computed/*methods
Adult ; Aged ; Aged, 80 and over ; Angiography/methods ; Catheterization, Peripheral/methods ; Female ; Hepatic Artery/diagnostic imaging ; Humans ; Liver Neoplasms/diagnostic imaging ; Male ; Middle Aged ; Neoplasm Recurrence, Local/diagnostic imaging ; Surgery, Computer-Assisted/methods ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Anaesthetic management during open and percutaneous irreversible electroporation.
Autorzy :
Nielsen K; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Scheffer HJ; Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Vieveen JM; Department of Anesthesiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
van Tilborg AA; Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Meijer S; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
van Kuijk C; Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
van den Tol MP; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Meijerink MR; Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Bouwman RA; Department of Anesthesiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands Department of Anaesthesiology, Catharina Hospital, Michelangelolaan 2, 5623 EJ Eindhoven .
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Źródło :
British journal of anaesthesia [Br J Anaesth] 2014 Dec; Vol. 113 (6), pp. 985-92. Date of Electronic Publication: 2014 Aug 30.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Ablation Techniques/*methods
Anesthesia, General/*methods
Electroporation/*methods
Neoplasms/*surgery
Ablation Techniques/adverse effects ; Aged ; Arrhythmias, Cardiac/etiology ; Contraindications ; Electrocardiography ; Electroencephalography ; Female ; Humans ; Hypertension/etiology ; Kidney Neoplasms/surgery ; Liver Neoplasms/secondary ; Liver Neoplasms/surgery ; Male ; Middle Aged ; Minimally Invasive Surgical Procedures/adverse effects ; Minimally Invasive Surgical Procedures/methods ; Monitoring, Intraoperative/methods ; Muscle Contraction ; Pain Measurement/methods ; Pain, Postoperative/etiology ; Pancreatic Neoplasms/surgery ; Pelvic Neoplasms/surgery ; Perioperative Care/methods ; Prospective Studies
Czasopismo naukowe
Tytuł :
Sulfated sugars in the extracellular matrix orchestrate ovarian cancer development: 'when sweet turns sour'.
Autorzy :
Vallen MJ; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, PO Box 9101, 6500 HB Nijmegen, The Netherlands; Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address: .
van der Steen SC; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, PO Box 9101, 6500 HB Nijmegen, The Netherlands; Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
van Tilborg AA; Department of Pathology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
Massuger LF; Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
van Kuppevelt TH; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
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Źródło :
Gynecologic oncology [Gynecol Oncol] 2014 Nov; Vol. 135 (2), pp. 371-81. Date of Electronic Publication: 2014 Aug 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinogenesis/*metabolism
Chondroitin Sulfates/*metabolism
Extracellular Matrix/*metabolism
Glycosaminoglycans/*metabolism
Neovascularization, Pathologic/*metabolism
Ovarian Neoplasms/*metabolism
Cell Adhesion ; Cell Movement ; Chondroitin Sulfates/immunology ; Female ; Glycosaminoglycans/immunology ; Humans ; Neoplasm Invasiveness ; Ovarian Neoplasms/immunology ; Ovarian Neoplasms/pathology ; Tumor Escape/immunology
Czasopismo naukowe
Tytuł :
Ablation of colorectal liver metastases by irreversible electroporation: results of the COLDFIRE-I ablate-and-resect study.
Autorzy :
Scheffer HJ; Department of Radiology and Nuclear Medicine, VU University Medical Centre, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands, .
Nielsen K
van Tilborg AA
Vieveen JM
Bouwman RA
Kazemier G
Niessen HW
Meijer S
van Kuijk C
van den Tol MP
Meijerink MR
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Źródło :
European radiology [Eur Radiol] 2014 Oct; Vol. 24 (10), pp. 2467-75. Date of Electronic Publication: 2014 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Ablation Techniques/*methods
Colorectal Neoplasms/*surgery
Electroporation/*methods
Hepatectomy/*methods
Liver Neoplasms/*secondary
Surgery, Computer-Assisted/*methods
Aged ; Colorectal Neoplasms/pathology ; Feasibility Studies ; Female ; Humans ; Laparotomy ; Liver Neoplasms/diagnosis ; Liver Neoplasms/surgery ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neoplasm Staging/methods ; Positron-Emission Tomography ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Mutational profiling of kinases in glioblastoma.
Autorzy :
Bleeker FE; Department of Oncology, University of Torino, SP 142, Km 3,95, Candiolo, Torino, 10060, Italy; Candiolo Cancer Institute - FPO, IRCCS, Candiolo, Torino, Italy. .
Lamba S
Zanon C
Molenaar RJ
Hulsebos TJ
Troost D
van Tilborg AA
Vandertop WP
Leenstra S
van Noorden CJ
Bardelli A
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Źródło :
BMC cancer [BMC Cancer] 2014 Sep 26; Vol. 14, pp. 718. Date of Electronic Publication: 2014 Sep 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Mutational Analysis*
Glioblastoma/*enzymology
Glioblastoma/*genetics
Phosphotransferases/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cell Line, Tumor ; Female ; GTP Phosphohydrolases/genetics ; Humans ; Isocitrate Dehydrogenase/genetics ; MAP Kinase Signaling System ; Male ; Membrane Proteins/genetics ; Middle Aged ; Mutation ; PTEN Phosphohydrolase/genetics ; Tumor Suppressor Protein p53/genetics ; Young Adult
Czasopismo naukowe
Tytuł :
The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone.
Autorzy :
Molenaar RJ; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Verbaan D; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Lamba S; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Zanon C; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Jeuken JW; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Boots-Sprenger SH; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Wesseling P; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Hulsebos TJ; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Troost D; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
van Tilborg AA; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Leenstra S; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Vandertop WP; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Bardelli A; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
van Noorden CJ; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
Bleeker FE; Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (R.J.M., C.J.F.v.N.); Neurosurgical Center Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (F.E.B., D.V., W.P.V.); Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment, University of Torino Medical School, Candiolo, Italy (S.La., C.Z., A.B., F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands (J.W.M.J., S.H.E.B.-S., P.W.); Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands (P.W.); Department of Neurogenetics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (T.J.M.H.); Department of Neuropathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (D.T., A.A.v.T.); Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands (W.P.V.); Department of Neurosurgery, St. Elisabeth Hospital Tilburg, The Netherlands (S.Le.); Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands (S.Le.); FIRC Institute of Molecular Oncology, Milan, Italy (A.B.)Present affiliation: Department of Clinical Genetics, Academic Medical Center and University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands (F.E.B.); Department of Pathology, Radboud University Medical Center Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (A.A.v.T.); Department of Neurology, Radboud University Medical Centre Nijmegen, Geert Grooteplein-Zuid 10, 6525 GA Nijmegen, The Netherlands (S.H.E.B.-S.); Department of Pathology, Stichting PAMM, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands (J.W.M.J.).
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Źródło :
Neuro-oncology [Neuro Oncol] 2014 Sep; Vol. 16 (9), pp. 1263-73. Date of Electronic Publication: 2014 Feb 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Brain Neoplasms/*genetics
Brain Neoplasms/*mortality
DNA Modification Methylases/*genetics
DNA Repair Enzymes/*genetics
Glioblastoma/*genetics
Glioblastoma/*mortality
Isocitrate Dehydrogenase/*genetics
Tumor Suppressor Proteins/*genetics
Adult ; Aged ; Aged, 80 and over ; DNA Methylation ; Epigenesis, Genetic ; Female ; Humans ; Male ; Middle Aged ; Survival Analysis
Czasopismo naukowe
Tytuł :
The use of PET-MRI in the follow-up after radiofrequency- and microwave ablation of colorectal liver metastases.
Autorzy :
Nielsen K
Scheffer HJ
Pieters IC
van Tilborg AA
van Waesberghe JH
Oprea-Lager DE
Meijerink MR
Kazemier G
Hoekstra OS
Schreurs HW
Sietses C
Meijer S
Comans EF
van den Tol PM; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands. .
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Źródło :
BMC medical imaging [BMC Med Imaging] 2014 Aug 08; Vol. 14, pp. 27. Date of Electronic Publication: 2014 Aug 08.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Fluorodeoxyglucose F18*
Radiopharmaceuticals*
Colorectal Neoplasms/*diagnosis
Liver Neoplasms/*diagnosis
Liver Neoplasms/*secondary
Magnetic Resonance Imaging/*methods
Positron-Emission Tomography/*methods
Catheter Ablation/methods ; Colorectal Neoplasms/therapy ; Early Detection of Cancer ; Follow-Up Studies ; Humans ; Liver Neoplasms/therapy ; Multimodal Imaging/methods ; Observer Variation ; Prospective Studies
Czasopismo naukowe
Tytuł :
Transcatheter CT arterial portography and CT hepatic arteriography for liver tumor visualization during percutaneous ablation.
Autorzy :
van Tilborg AA; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, the Netherlands. Electronic address: .
Scheffer HJ; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, the Netherlands.
Nielsen K; Department of Surgical Oncology, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, the Netherlands.
van Waesberghe JH; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, the Netherlands.
Comans EF; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, the Netherlands.
van Kuijk C; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, the Netherlands.
van den Tol PM; Department of Surgical Oncology, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, the Netherlands.
Meijerink MR; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081HV Amsterdam, the Netherlands.
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Źródło :
Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2014 Jul; Vol. 25 (7), pp. 1101-1111.e4. Date of Electronic Publication: 2014 Apr 20.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Catheter Ablation*/adverse effects
Catheter Ablation*/instrumentation
Tomography, X-Ray Computed*/instrumentation
Bile Duct Neoplasms/*therapy
Carcinoma, Hepatocellular/*therapy
Cholangiocarcinoma/*therapy
Hepatic Artery/*diagnostic imaging
Liver Neoplasms/*therapy
Portography/*methods
Radiography, Interventional/*methods
Adult ; Aged ; Bile Duct Neoplasms/diagnostic imaging ; Bile Duct Neoplasms/pathology ; Bile Ducts, Intrahepatic/diagnostic imaging ; Bile Ducts, Intrahepatic/pathology ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/pathology ; Cholangiocarcinoma/diagnostic imaging ; Cholangiocarcinoma/pathology ; Colorectal Neoplasms/pathology ; Contrast Media ; Equipment Design ; Feasibility Studies ; Female ; Fluoroscopy ; Humans ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/secondary ; Male ; Middle Aged ; Portography/instrumentation ; Predictive Value of Tests ; Radiography, Interventional/instrumentation ; Time Factors ; Treatment Outcome ; Vascular Access Devices
Czasopismo naukowe
Tytuł :
Müllerian precursor lesions in serous ovarian cancer patients: using the SEE-Fim and SEE-End protocol.
Autorzy :
Mingels MJ; Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
van Ham MA; Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
de Kievit IM; Department of Pathology, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Snijders MP; Department of Obstetrics and Gynecology, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
van Tilborg AA; 1] Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands [2] Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Bulten J; Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Massuger LF; Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Pokaż więcej
Źródło :
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2014 Jul; Vol. 27 (7), pp. 1002-13. Date of Electronic Publication: 2013 Dec 06.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Cystadenocarcinoma, Serous/*pathology
Fallopian Tube Neoplasms/*pathology
Mullerian Ducts/*pathology
Ovarian Neoplasms/*pathology
Precancerous Conditions/*pathology
Adult ; Aged ; Female ; Humans ; Middle Aged ; Prospective Studies
Czasopismo naukowe
Tytuł :
Irreversible electroporation for nonthermal tumor ablation in the clinical setting: a systematic review of safety and efficacy.
Autorzy :
Scheffer HJ; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands. Electronic address: .
Nielsen K; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
de Jong MC; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
van Tilborg AA; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Vieveen JM; Department of Anesthesiology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Bouwman AR; Department of Anesthesiology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Meijer S; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
van Kuijk C; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
van den Tol PM; Department of Surgery, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
Meijerink MR; Department of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.
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Źródło :
Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2014 Jul; Vol. 25 (7), pp. 997-1011; quiz 1011. Date of Electronic Publication: 2014 Mar 18.
Typ publikacji :
Journal Article; Review; Systematic Review
MeSH Terms :
Electrochemotherapy*/adverse effects
Electrochemotherapy*/mortality
Ablation Techniques/*methods
Neoplasms/*surgery
Ablation Techniques/adverse effects ; Ablation Techniques/mortality ; Diffusion Magnetic Resonance Imaging ; Humans ; Multimodal Imaging ; Neoplasms/mortality ; Neoplasms/pathology ; Positron-Emission Tomography ; Postoperative Complications/mortality ; Predictive Value of Tests ; Risk Factors ; Time Factors ; Tomography, X-Ray Computed ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Plasminogen activators are involved in angiostatin generation in vivo in benign and malignant ovarian tumor cyst fluids.
Autorzy :
van Tilborg AA; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands.
Sweep FC; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Geurts-Moespot AJ; Department of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Wetzels AM; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands.
de Waal RM; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands.
Westphal JR; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands.
Massuger LF; Department of Obstetrics and Gynaecology, Radboud University Medical Center, Nijmegen, The Netherlands.
Pokaż więcej
Źródło :
International journal of oncology [Int J Oncol] 2014 Apr; Vol. 44 (4), pp. 1394-400. Date of Electronic Publication: 2014 Feb 14.
Typ publikacji :
Journal Article
MeSH Terms :
Angiostatins/*biosynthesis
Ovarian Cysts/*pathology
Ovarian Neoplasms/*pathology
Plasminogen/*metabolism
Plasminogen Activators/*metabolism
Cyst Fluid ; Dermoid Cyst/pathology ; Endometriosis/pathology ; Female ; Humans ; Ovarian Follicle/pathology ; Tissue Plasminogen Activator/metabolism ; Urokinase-Type Plasminogen Activator/metabolism
Czasopismo naukowe

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