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Wyszukujesz frazę ""van de Graaf SFJ"" wg kryterium: Autor


Tytuł:
Galectin-3 and prohibitin 1 are autoantigens in IgG4-related cholangitis without clear-cut protective effects against toxic bile acids.
Autorzy:
Kersten R; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.
Trampert DC; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.
Hubers LM; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.
Tolenaars D; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.
Vos HR; Oncode Institute and Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.
Beuers U; Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.
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Źródło:
Frontiers in immunology [Front Immunol] 2024 Jan 25; Vol. 14, pp. 1251134. Date of Electronic Publication: 2024 Jan 25 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Cholangitis*/immunology
Immunoglobulin G4-Related Disease*
Humans ; Annexins ; Autoantibodies ; Autoantigens ; Bile Acids and Salts ; Chromatography, Liquid ; Galectin 3/immunology ; Immunoglobulin G ; Prohibitins/immunology ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł:
IgG4-related cholangitis - a mimicker of fibrosing and malignant cholangiopathies.
Autorzy:
Kersten R; Department of Gastroenterology & Hepatology, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
Trampert DC; Department of Gastroenterology & Hepatology, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
Herta T; Department of Gastroenterology & Hepatology, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, Amsterdam, the Netherlands; Division of Hepatology, Department of Medicine II, Leipzig University Medical Center, Leipzig, Germany.
Hubers LM; Department of Gastroenterology & Hepatology, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
Maillette de Buy Wenniger LJ; Department of Ophthalmology, Amsterdam University Medical Centers, the Netherlands.
Verheij J; Department of Pathology, Amsterdam University Medical Centers, the Netherlands.
van de Graaf SFJ; Department of Gastroenterology & Hepatology, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
Beuers U; Department of Gastroenterology & Hepatology, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, Amsterdam, the Netherlands. Electronic address: .
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Źródło:
Journal of hepatology [J Hepatol] 2023 Dec; Vol. 79 (6), pp. 1502-1523. Date of Electronic Publication: 2023 Aug 18.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunoglobulin G4-Related Disease*/diagnosis
Immunoglobulin G4-Related Disease*/complications
Cholangitis*/etiology
Bile Duct Neoplasms*
Cholangitis, Sclerosing*
Autoimmune Diseases*
Humans ; Immunoglobulin G ; Autoantigens/therapeutic use ; Bile Ducts, Intrahepatic
Czasopismo naukowe
Tytuł:
Combined inhibition of bile salt synthesis and intestinal uptake reduces cholestatic liver damage and colonic bile salts in mice.
Autorzy:
Kunst RF; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Bolt I; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, Amsterdam, The Netherlands.
van Dasselaar RDJ; LinXis BV, Amsterdam, The Netherlands.
Nijmeijer BA; LinXis BV, Amsterdam, The Netherlands.
Beuers U; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Oude Elferink RPJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
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Źródło:
JHEP reports : innovation in hepatology [JHEP Rep] 2023 Sep 25; Vol. 6 (1), pp. 100917. Date of Electronic Publication: 2023 Sep 25 (Print Publication: 2024).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Bile Salts by the Back Road.
Autorzy:
Oude Elferink RPJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, Research Institute AGEM, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Van De Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, Research Institute AGEM, University of Amsterdam, Amsterdam, the Netherlands.
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Źródło:
Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2023; Vol. 16 (2), pp. 319-320. Date of Electronic Publication: 2023 May 24.
Typ publikacji:
Editorial; Comment
MeSH Terms:
Bile Acids and Salts*/metabolism
Liver*/metabolism
Enterohepatic Circulation
Opinia redakcyjna
Tytuł:
Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice.
Autorzy:
Kunst RF; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.
de Waart DR; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.
Wolters F; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.
Duijst S; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.
Vogels EW; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.
Bolt I; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.
Verheij J; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.; Department of Pathology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Beuers U; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Oude Elferink RPJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Gastroenterology, Endocrinology and Metabolism (AGEM), Amsterdam University Medical Centers, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
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Źródło:
JHEP reports : innovation in hepatology [JHEP Rep] 2022 Aug 27; Vol. 4 (11), pp. 100573. Date of Electronic Publication: 2022 Aug 27 (Print Publication: 2022).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Differential and organ-specific functions of organic solute transporter α and β in experimental cholestasis.
Autorzy:
van de Wiel SMW; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.
Porteiro B; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.; CIMUS, Universidade de Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, 15782, Spain.
Belt SC; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.
Vogels EWM; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.
Bolt I; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.
Vermeulen JLM; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.
de Waart DR; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.
Verheij J; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.; Department of Pathology, Amsterdam UMC, University of Amsterdam, the Netherlands.
Muncan V; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, the Netherlands.
Oude Elferink RPJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, the Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, the Netherlands.
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Źródło:
JHEP reports : innovation in hepatology [JHEP Rep] 2022 Mar 05; Vol. 4 (5), pp. 100463. Date of Electronic Publication: 2022 Mar 05 (Print Publication: 2022).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Role of the IgG4-related cholangitis autoantigen annexin A11 in cholangiocyte protection.
Autorzy:
Herta T; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands.
Kersten R; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands; Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, USA.
Chang JC; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands.
Hubers L; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands.
Go S; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands.
Tolenaars D; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands.
Paulusma CC; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands.
Nathanson MH; Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, USA.
Elferink RO; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands.
van de Graaf SFJ; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands.
Beuers U; Department of Gastroenterology and Hepatology and Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands. Electronic address: .
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Źródło:
Journal of hepatology [J Hepatol] 2022 Feb; Vol. 76 (2), pp. 319-331. Date of Electronic Publication: 2021 Oct 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protective Factors*
Cholangitis/*etiology
Immunoglobulin G4-Related Disease/*complications
Aged ; Annexins/pharmacology ; Annexins/therapeutic use ; Autoantigens/pharmacology ; Autoantigens/therapeutic use ; Biopsy/methods ; Biopsy/statistics & numerical data ; Cholangitis/physiopathology ; Female ; Humans ; Immunoglobulin G4-Related Disease/physiopathology ; Liver/pathology ; Male ; Middle Aged
Czasopismo naukowe
Tytuł:
OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spf mice, and govern susceptibility to RNA-based therapies.
Autorzy:
Sacchetto C; Department of Life Sciences and Biotechnology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy.; Department of Molecular Genetics, University of Maastricht, Maastricht, The Netherlands.
Peretto L; Department of Life Sciences and Biotechnology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy.
Baralle F; Liver Research Center, Q AREA Science Park, Trieste, Italy.
Maestri I; Department of Translational Medicine and for Romagna, Pathology Unit of Pathologic Anatomy, Histology and Cytology, University of Ferrara, Ferrara, Italy.
Tassi F; Department of Life Sciences and Biotechnology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy.
Bernardi F; Department of Life Sciences and Biotechnology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands.
Pagani F; Human Molecular Genetics, ICGEB - International Center for Genetic Engineering and Biotechnology, Trieste, Italy.
Pinotti M; Department of Life Sciences and Biotechnology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy. .
Balestra D; Department of Life Sciences and Biotechnology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy. .
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Źródło:
Molecular medicine (Cambridge, Mass.) [Mol Med] 2021 Dec 14; Vol. 27 (1), pp. 157. Date of Electronic Publication: 2021 Dec 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA Splicing*
Ornithine Carbamoyltransferase/*genetics
Animals ; Cell Line, Tumor ; Humans ; Introns ; Mice ; Mutation ; RNA/therapeutic use ; Ribonucleoprotein, U1 Small Nuclear/genetics
Czasopismo naukowe
Tytuł:
On the Mechanisms of Biliary Flux.
Autorzy:
Vartak N; Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany.
Drasdo D; National Institute for Research in Digital Science and Technology, Paris, France.
Geisler F; Clinic and Polyclinic for Internal Medicine II, Kinikum Rechts der Isar, Technical University Munich, Munich, Germany.
Itoh T; Institute for Quantitative Biosciences, the University of Tokyo, Tokyo, Japan.
P J Oude Elferink R; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Chiang J; North-East Ohio Medical University, Rootstown, OH, USA.
Keitel V; Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty at Heinrich-Heine-University, Düsseldorf, Germany.
Trauner M; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Jansen P; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Hengstler JG; Leibniz Research Centre for Working Environment and Human Factors, Dortmund, Germany.
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Źródło:
Hepatology (Baltimore, Md.) [Hepatology] 2021 Dec; Vol. 74 (6), pp. 3497-3512. Date of Electronic Publication: 2021 Sep 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Bile/*metabolism
Liver/*metabolism
Animals ; Bile Acids and Salts/metabolism ; Bile Ducts/metabolism ; Humans ; Mice ; Osmosis
Czasopismo naukowe
Tytuł:
Inhibition of autotaxin by bile salts and bile salt-like molecules increases its expression by feedback regulation.
Autorzy:
Langedijk JAGM; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam, the Netherlands.
Tolenaars D; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam, the Netherlands.
Bolier R; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam, the Netherlands.
Lee YT; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam, the Netherlands.
Meurs A; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam, the Netherlands.
Williamson C; Division of Women's Health, King's College London, London, UK.
Adorini L; Intercept Pharmaceuticals, San Diego, CA, USA.
van de Graaf SFJ; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam, the Netherlands.
Beuers U; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam, the Netherlands.
Elferink RO; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, AGEM, Amsterdam, the Netherlands. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2021 Nov 01; Vol. 1867 (11), pp. 166239. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji:
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms:
Bile Acids and Salts/*metabolism
Liver Cirrhosis, Biliary/*complications
Lysophospholipids/*metabolism
Phosphoric Diester Hydrolases/*metabolism
Pruritus/*metabolism
Drainage ; Enzyme Assays ; Feedback, Physiological ; Humans ; Liver Cirrhosis, Biliary/blood ; Liver Cirrhosis, Biliary/metabolism ; Liver Cirrhosis, Biliary/therapy ; Pruritus/blood ; Pruritus/etiology ; Receptors, Lysophosphatidic Acid/metabolism
Czasopismo naukowe
Tytuł:
Applicability of different cell line-derived dendritic cell-like cells in autophagy research.
Autorzy:
Prins MMC; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
van Roest M; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Vermeulen JLM; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Tjabringa GS; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Koelink PJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
Wildenberg ME; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
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Źródło:
Journal of immunological methods [J Immunol Methods] 2021 Oct; Vol. 497, pp. 113106. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Cell Differentiation*
Adenine/*analogs & derivatives
Autophagy/*drug effects
Dendritic Cells/*drug effects
Macrolides/*pharmacology
Monocytes/*immunology
Sirolimus/*pharmacology
Adenine/pharmacology ; Autophagy/genetics ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/metabolism ; Cytokines/metabolism ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Dendritic Cells/pathology ; Flow Cytometry ; Genotype ; HL-60 Cells ; Humans ; Microscopy, Fluorescence ; Monocytes/metabolism ; Monocytes/pathology ; Phenotype ; Polymorphism, Single Nucleotide ; THP-1 Cells ; U937 Cells
Czasopismo naukowe
Tytuł:
Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP.
Autorzy:
Appelman MD; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands.
Wettengel JM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany.
Protzer U; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany.
Oude Elferink RPJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Aug; Vol. 1866 (8), pp. 158960. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Virus Internalization*
Bile Acids and Salts/*metabolism
Hepatitis B virus/*physiology
Organic Anion Transporters, Sodium-Dependent/*metabolism
Symporters/*metabolism
Animals ; Biological Transport ; Humans
Czasopismo naukowe
Tytuł:
Erratum to: "Hepatobiliary acid-base homeostasis: Insights from analogous secretory epithelia" (J Hepatol 2021; 74: 428-441).
Autorzy:
Trampert DC; Amsterdam UMC, University of Amsterdam, Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Meibergdreef 9, Amsterdam, the Netherlands.
van de Graaf SFJ; Amsterdam UMC, University of Amsterdam, Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Meibergdreef 9, Amsterdam, the Netherlands.
Jongejan A; Amsterdam UMC, University of Amsterdam, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Meibergdreef 9, Amsterdam, the Netherlands.
Oude Elferink RPJ; Amsterdam UMC, University of Amsterdam, Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Meibergdreef 9, Amsterdam, the Netherlands.
Beuers U; Amsterdam UMC, University of Amsterdam, Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Meibergdreef 9, Amsterdam, the Netherlands. Electronic address: .
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Źródło:
Journal of hepatology [J Hepatol] 2021 Aug; Vol. 75 (2), pp. 497. Date of Electronic Publication: 2021 May 13.
Typ publikacji:
Published Erratum
Tytuł:
Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
Autorzy:
Zaufel A; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Austria.
van de Wiel SMW; Tytgat Institute for Liver and Intestinal Research, & Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam University Medical Centers, the Netherlands.
Yin L; The School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland.
Fauler G; Clinical Institute of Medical and Chemical Laboratory Diagnostics Medical, University of Graz, Austria.
Chien D; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States of America.
Dong X; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States of America.
Gilmer JF; The School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland.
Truong JK; Division of Pediatric Gastroenterology, Hepatology & Nutrition, Emory University School of Medicine, Atlanta, GA, USA.
Dawson PA; Division of Pediatric Gastroenterology, Hepatology & Nutrition, Emory University School of Medicine, Atlanta, GA, USA.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, & Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam University Medical Centers, the Netherlands.
Fickert P; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Austria.
Moustafa T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Austria. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2021 Aug 01; Vol. 1867 (8), pp. 166153. Date of Electronic Publication: 2021 Apr 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Bile Acids and Salts/*pharmacology
Receptors, Cytoplasmic and Nuclear/*metabolism
Animals ; Caco-2 Cells ; Cell Line ; Cell Line, Tumor ; Cholestasis/drug therapy ; Cholestasis/metabolism ; Disease Models, Animal ; Fibroblast Growth Factors/metabolism ; HEK293 Cells ; Hep G2 Cells ; Humans ; Ileum/drug effects ; Ileum/metabolism ; Isoxazoles/pharmacology ; Ligands ; Liver/drug effects ; Liver/metabolism ; Male ; Mice ; RNA, Messenger/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Targeting the Four Pillars of Enterohepatic Bile Salt Cycling; Lessons From Genetics and Pharmacology.
Autorzy:
Kunst RF; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.
Verkade HJ; Pediatric Gastroenterology/Hepatology, Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Oude Elferink RPJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
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Źródło:
Hepatology (Baltimore, Md.) [Hepatology] 2021 Jun; Vol. 73 (6), pp. 2577-2585. Date of Electronic Publication: 2021 May 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
ATP Binding Cassette Transporter, Subfamily B, Member 11*/genetics
ATP Binding Cassette Transporter, Subfamily B, Member 11*/metabolism
Membrane Transport Proteins*/genetics
Membrane Transport Proteins*/metabolism
Organic Anion Transporters, Sodium-Dependent*/antagonists & inhibitors
Organic Anion Transporters, Sodium-Dependent*/genetics
Organic Anion Transporters, Sodium-Dependent*/metabolism
Receptors, G-Protein-Coupled*/genetics
Receptors, G-Protein-Coupled*/metabolism
Symporters*/antagonists & inhibitors
Symporters*/genetics
Symporters*/metabolism
Bile Acids and Salts/*metabolism
Enterohepatic Circulation/*physiology
Animals ; Biological Transport, Active/drug effects ; Biological Transport, Active/physiology ; Drug Development ; Enterohepatic Circulation/drug effects ; Humans
Czasopismo naukowe
Tytuł:
Thiopurines correct the effects of autophagy impairment on intestinal healing - a potential role for ARHGAP18/RhoA.
Autorzy:
Prins MMC; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers (UMC), location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Giugliano FP; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers (UMC), location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
van Roest M; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers (UMC), location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers (UMC), location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Koelink PJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers (UMC), location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Wildenberg ME; Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers (UMC), location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam UMC, location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
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Źródło:
Disease models & mechanisms [Dis Model Mech] 2021 Apr 01; Vol. 14 (4). Date of Electronic Publication: 2021 Apr 23.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy*/drug effects
Wound Healing*/drug effects
GTPase-Activating Proteins/*metabolism
Intestines/*pathology
Sulfhydryl Compounds/*pharmacology
rhoA GTP-Binding Protein/*metabolism
Cell Movement/drug effects ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; HT29 Cells ; Humans ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/pathology ; Intestines/drug effects ; Organoids/drug effects ; Organoids/metabolism ; Phenotype ; Sequestosome-1 Protein/metabolism
Czasopismo naukowe

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