Wszystkie pola: "10642553" - OpacWWW

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Tytuł:: Regulation of T-cell Receptor Gene Expression by Three-Dimensional Locus Conformation and Enhancer Function.
Autorzy:: Rodríguez-Caparrós A; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Álvarez-Santiago J; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Del Valle-Pastor MJ; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Suñé C; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
López-Ros J; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.
Hernández-Munain C; Institute of Parasitology and Biomedicine 'López-Neyra'-Spanish Scientific Research Council (IPBLN-CSIC), Parque Tecnológico de Ciencias de la Salud (PTS), 18016 Granada, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Nov 11; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 11.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Enhancer Elements, Genetic/*genetics
Gene Expression Regulation/*genetics
Genes, T-Cell Receptor/*genetics
T-Lymphocytes/*immunology
Animals ; Chromatin/genetics ; Chromatin/immunology ; Enhancer Elements, Genetic/immunology ; Gene Expression Regulation/immunology ; Genes, T-Cell Receptor/immunology ; Humans ; Signal Transduction/genetics ; Signal Transduction/immunology ; Transcription, Genetic/genetics ; Transcription, Genetic/immunology ; V(D)J Recombination/genetics ; V(D)J Recombination/immunology

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Skocz do pozycji: 2.

Tytuł:: HAT2 mediates histone H4K4 acetylation and affects micrococcal nuclease sensitivity of chromatin in Leishmania donovani.
Autorzy:: Jha PK; Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.
Khan MI; Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.
Mishra A; Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.
Das P; Molecular Biology Division, Rajendra Memorial Research Institute of Medical Sciences, Patna, Bihar, India.
Sinha KK; Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 May 09; Vol. 12 (5), pp. e0177372. Date of Electronic Publication: 2017 May 09 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Chromatin/*metabolism
Histones/*metabolism
Leishmania donovani/*metabolism
Micrococcal Nuclease/*metabolism
Protozoan Proteins/*metabolism
Acetylation ; Amino Acid Sequence ; Animals ; Histones/chemistry ; Sequence Homology, Amino Acid

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Skocz do pozycji: 3.

Tytuł:: The 3'-Jα Region of the TCRα Locus Bears Gene Regulatory Activity in Thymic and Peripheral T Cells.
Autorzy:: Kučerová-Levisohn M; Department of Biological Sciences, City University of New York, Hunter College, New York, New York, United States of America; Doctoral Program in Biology, City University of New York, Graduate Center, New York, New York, United States of America.
Knirr S; Department of Biological Sciences, City University of New York, Hunter College, New York, New York, United States of America.
Mejia RI; Department of Biological Sciences, City University of New York, Hunter College, New York, New York, United States of America.
Ortiz BD; Department of Biological Sciences, City University of New York, Hunter College, New York, New York, United States of America; Doctoral Program in Biology, City University of New York, Graduate Center, New York, New York, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Jul 15; Vol. 10 (7), pp. e0132856. Date of Electronic Publication: 2015 Jul 15 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Gene Expression Regulation*
Genetic Loci*
Receptors, Antigen, T-Cell, alpha-beta/*genetics
T-Lymphocytes/*cytology
Thymus Gland/*cytology
Animals ; Chromatin/genetics ; Deoxyribonuclease I/metabolism ; Genes, Reporter ; Humans ; Mice, Inbred C57BL ; Mice, Transgenic ; Sequence Deletion ; T-Lymphocytes/metabolism

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Skocz do pozycji: 4.

Tytuł:: Multiple factors influence the contribution of individual immunoglobulin light chain genes to the naïve antibody repertoire.
Autorzy:: Fitzsimmons SP
Aydanian AG
Clark KJ
Shapiro MA; Laboratory of Molecular and Developmental Immunology, Division of Monoclonal Antibodies, OBP, CDER, FDA, 10903 New Hampshire Avenue, Silver Spring 20993, MD, USA. .; Pokaż więcej
Źródło:: BMC immunology [BMC Immunol] 2014 Oct 30; Vol. 15, pp. 51. Date of Electronic Publication: 2014 Oct 30.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Genes, Immunoglobulin Light Chain*
Antibodies/*genetics
Animals ; Base Sequence ; Female ; Gene Rearrangement, B-Lymphocyte, Light Chain ; Immunoglobulin Heavy Chains/genetics ; Male ; Mice, Inbred BALB C ; Molecular Sequence Data ; Precursor Cells, B-Lymphoid/metabolism ; Promoter Regions, Genetic/genetics ; Receptors, Antigen, B-Cell/metabolism ; Recombination, Genetic/genetics

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Skocz do pozycji: 5.

Tytuł:: Genetic and epigenetic determinants mediate proneness of oncogene breakpoint sites for involvement in TCR translocations.
Autorzy:: Larmonie NS; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
van der Spek A; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Bogers AJ; Department of Cardio-thoracic Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
van Dongen JJ; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Langerak AW; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Pokaż więcej
Źródło:: Genes and immunity [Genes Immun] 2014 Mar; Vol. 15 (2), pp. 72-81. Date of Electronic Publication: 2013 Dec 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chromosome Breakpoints*
Adaptor Proteins, Signal Transducing/*genetics
Basic Helix-Loop-Helix Transcription Factors/*genetics
Homeodomain Proteins/*genetics
LIM Domain Proteins/*genetics
Proto-Oncogene Proteins/*genetics
Receptors, Antigen, T-Cell/*genetics
Base Sequence ; Child ; Child, Preschool ; DNA Breaks, Double-Stranded ; DNA Methylation ; Epigenesis, Genetic ; Humans ; Infant ; Infant, Newborn ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Proto-Oncogene Proteins c-bcr/genetics ; Sequence Analysis, DNA ; T-Cell Acute Lymphocytic Leukemia Protein 1 ; Thymocytes/cytology ; Translocation, Genetic/genetics ; V(D)J Recombination/genetics

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Skocz do pozycji: 6.

Tytuł:: Epigenetic aspects of lymphocyte antigen receptor gene rearrangement or 'when stochasticity completes randomness'.
Autorzy:: Jaeger S; Centre d'Immunologie de Marseille-Luminy (CIML), Institut National de la Santé et de la Recherche Médicale (Inserm) U1104, Centre National de la Recherche Scientifique (CNRS)UMR7280, Aix-Marseille University UM2, Marseille, France.
Fernandez B
Ferrier P; Pokaż więcej
Źródło:: Immunology [Immunology] 2013 Jun; Vol. 139 (2), pp. 141-50.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Epigenesis, Genetic/*immunology
Gene Rearrangement, T-Lymphocyte/*immunology
Receptors, Antigen, T-Cell/*immunology
V(D)J Recombination/*immunology
Animals ; Epigenesis, Genetic/genetics ; Gene Rearrangement, T-Lymphocyte/genetics ; Humans ; Models, Genetic ; Models, Immunological ; Receptors, Antigen, T-Cell/genetics ; Stochastic Processes ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; V(D)J Recombination/genetics

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Skocz do pozycji: 7.

Tytuł:: The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution.
Autorzy:: Waanders E; Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Scheijen B
van der Meer LT
van Reijmersdal SV
van Emst L
Kroeze Y
Sonneveld E
Hoogerbrugge PM
van Kessel AG
van Leeuwen FN
Kuiper RP; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2012; Vol. 8 (2), pp. e1002533. Date of Electronic Publication: 2012 Feb 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Clonal Evolution*
Gene Deletion*
Neoplasm Proteins/*genetics
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*genetics
Acute Disease ; Child ; Humans ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Precursor Cells, B-Lymphoid/metabolism ; Precursor Cells, B-Lymphoid/pathology

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Skocz do pozycji: 8.

Tytuł:: RAG: a recombinase diversified.
Autorzy:: Matthews AG; Howard Hughes Medical Institute, Department of Biology, Cambridge, Massachusetts, USA. .
Oettinger MA; Pokaż więcej
Źródło:: Nature immunology [Nat Immunol] 2009 Aug; Vol. 10 (8), pp. 817-21. Date of Electronic Publication: 2009 Jul 21.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Models, Biological*
Recombination, Genetic*
DNA-Binding Proteins/*immunology
Gene Rearrangement/*immunology
Homeodomain Proteins/*immunology
Nuclear Proteins/*immunology
VDJ Recombinases/*immunology
Animals ; B-Lymphocytes/immunology ; Chromatin/metabolism ; DNA Damage/immunology ; DNA Repair/immunology ; Histones/metabolism ; Humans ; Protein Binding

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Skocz do pozycji: 9.

Tytuł:: Genomic organization and recombinational unit duplication-driven evolution of ovine and bovine T cell receptor gamma loci.
Autorzy:: Vaccarelli G; Department of Genetics and Microbiology, University of Bari, via Amendola 165/A, 70126 Bari, Italy. />Miccoli MC
Antonacci R
Pesole G
Ciccarese S; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2008 Feb 18; Vol. 9, pp. 81. Date of Electronic Publication: 2008 Feb 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Evolution, Molecular*
Gene Duplication*
Gene Rearrangement*
Recombination, Genetic*
Genes, T-Cell Receptor gamma/*genetics
Genome/*genetics
Sheep, Domestic/*genetics
Animals ; Cattle ; Genomics ; Humans ; Mice ; Models, Genetic ; Mutagenesis, Insertional ; Repetitive Sequences, Nucleic Acid

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Skocz do pozycji: 10.

Tytuł:: Myb proteins regulate expression of histone variant H2A.Z during thymocyte development.
Autorzy:: Hooper J; Institute of Cancer Research, CRUK Centre for Cell and Molecular Biology, London, UK.
Maurice D
Argent-Katwala MJ
Weston K; Pokaż więcej
Źródło:: Immunology [Immunology] 2008 Feb; Vol. 123 (2), pp. 282-9. Date of Electronic Publication: 2007 Oct 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation/*immunology
Histones/*genetics
Proto-Oncogene Proteins c-myb/*physiology
T-Lymphocytes/*immunology
Animals ; Binding Sites/immunology ; Cell Line ; Gene Deletion ; Genes, myb ; Histones/metabolism ; Mice ; Mice, Transgenic ; Proto-Oncogene Proteins c-myb/genetics ; Proto-Oncogene Proteins c-myb/metabolism ; RNA, Messenger/genetics ; T-Lymphocyte Subsets/immunology ; Transcription, Genetic

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Skocz do pozycji: 11.

Tytuł:: Interleukin 15 controls the generation of the restricted T cell receptor repertoire of gamma delta intestinal intraepithelial lymphocytes.
Autorzy:: Zhao H; Department of Pathology, Graduate Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.
Nguyen H
Kang J; Pokaż więcej
Źródło:: Nature immunology [Nat Immunol] 2005 Dec; Vol. 6 (12), pp. 1263-71. Date of Electronic Publication: 2005 Nov 06.
Typ publikacji:: Journal Article
MeSH Terms:: Interleukin-15/*physiology
Intestinal Mucosa/*physiology
Receptors, Antigen, T-Cell, gamma-delta/*physiology
T-Lymphocyte Subsets/*physiology
Animals ; Cells, Cultured ; Chromatin/metabolism ; Gene Rearrangement, delta-Chain T-Cell Antigen Receptor ; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor ; Humans ; Intestinal Mucosa/cytology ; Intestinal Mucosa/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Receptors, Antigen, T-Cell, gamma-delta/genetics ; STAT5 Transcription Factor/deficiency ; STAT5 Transcription Factor/genetics ; STAT5 Transcription Factor/physiology

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Skocz do pozycji: 12.

Tytuł:: Assessing a role for enhancer-blocking activity in gene regulation within the murine T-cell receptor alpha/delta locus.
Autorzy:: Sleckman BP; Department of Pathology, Washington University School of Medicine, St Louis, MO, USA.
Carabana J
Zhong X
Krangel MS; Pokaż więcej
Źródło:: Immunology [Immunology] 2001 Sep; Vol. 104 (1), pp. 11-8.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Enhancer Elements, Genetic/*genetics
Gene Expression Regulation, Developmental/*immunology
Genes, T-Cell Receptor alpha/*genetics
Genes, T-Cell Receptor delta/*genetics
Animals ; Blotting, Northern ; Blotting, Southern ; Cell Differentiation/immunology ; Enhancer Elements, Genetic/immunology ; Gene Targeting ; Mice ; Mice, Transgenic ; Spleen/immunology ; Thymus Gland/immunology ; Transfection

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Skocz do pozycji: 13.

Tytuł:: Regulated T-cell development: a victim of multiple conspiracies.
Autorzy:: Hayday A; Peter Gorer Department of Immunobiology, Guy's Hospital, Kings College, London, UK. />Gibbons D; Pokaż więcej
Źródło:: Immunology [Immunology] 2001 Sep; Vol. 104 (1), pp. 8-10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Gene Expression Regulation/*immunology
Receptors, Antigen, T-Cell, alpha-beta/*genetics
Receptors, Antigen, T-Cell, gamma-delta/*genetics
T-Lymphocyte Subsets/*immunology
Animals ; Gene Rearrangement, T-Lymphocyte/immunology ; Humans ; Mice

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Skocz do pozycji: 14.

Tytuł:: Perspectives: transcription. A tail of histone acetylation and DNA recombination.
Autorzy:: Schlissel MS; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3200, USA.; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2000 Jan 21; Vol. 287 (5452), pp. 438-40.
Typ publikacji:: Comment; Journal Article
MeSH Terms:: Gene Rearrangement*
Genes, Immunoglobulin*
Genes, T-Cell Receptor*
Recombination, Genetic*
Saccharomyces cerevisiae Proteins*
Histones/*metabolism
Acetylation ; Acetyltransferases/metabolism ; Chromatin/metabolism ; DNA Nucleotidyltransferases/metabolism ; Enhancer Elements, Genetic ; Gene Rearrangement, T-Lymphocyte ; Genes, T-Cell Receptor alpha ; Genes, T-Cell Receptor delta ; Histone Acetyltransferases ; Nucleosomes/chemistry ; Nucleosomes/ultrastructure ; Transcription Factors ; Transcription, Genetic ; VDJ Recombinases

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