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Wyświetlanie 1-20 z 1835
Tytuł:
Rat Tumour Histopathology Associated with Experimental Chronic Dietary Exposure to Ochratoxin A in Prediction of the Mycotoxin's Risk for Human Cancers.
Autorzy:
Herman D; Pathology Department, County Hospital Timisoara, 300736 Timisoara, Romania.
Mantle P; Centre for Environmental Policy, Imperial College London, London SW7 2AZ, UK.
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Źródło:
Toxins [Toxins (Basel)] 2021 Mar 12; Vol. 13 (3). Date of Electronic Publication: 2021 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogenicity Tests*
Kidney Neoplasms/*chemically induced
Ochratoxins/*toxicity
Testicular Neoplasms/*chemically induced
Animals ; Dietary Exposure ; Humans ; Keratins/metabolism ; Kidney Neoplasms/metabolism ; Kidney Neoplasms/pathology ; Male ; Neprilysin/metabolism ; Rats, Inbred F344 ; Risk Assessment ; Risk Factors ; Testicular Neoplasms/metabolism ; Testicular Neoplasms/pathology ; Time Factors ; Vimentin/metabolism ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The 2-year rodent bioassay in drug and chemical carcinogenesis testing: Sensitivity, according to the framework of carcinogenic action.
Autorzy:
Suarez-Torres JD; Department of Pharmacy, Universidad Nacional de Colombia, Bogotá, Colombia.; Department of Toxicology, Universidad Nacional de Colombia, Bogotá, Colombia.; Institute of Pharmaceutical Research, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.
Jimenez-Orozco FA; Department of Pharmacology, Faculty of Medicine, Universidad Nacional Autónoma de México, Ciudad de Mexico, Mexico.
Ciangherotti CE; Institute of Pharmaceutical Research, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.; Laboratory of Neuropeptides, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.
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Źródło:
Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Jul; Vol. 30 (6), pp. 462-475. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji:
Journal Article
MeSH Terms:
Biological Assay*
Carcinogenicity Tests*
Carcinogens/*toxicity
Cell Transformation, Neoplastic/*chemically induced
Neoplasms/*chemically induced
Animals ; Databases, Factual ; Female ; Humans ; Male ; Mice ; Rats ; Risk Assessment ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Extended Analysis and Evidence Integration of Chloroprene as a Human Carcinogen.
Autorzy:
Sax SN; Ramboll US Corporation, Amherst, MA, USA.
Gentry PR; Ramboll US Corporation, Monroe, LA, USA.
Van Landingham C; Ramboll US Corporation, Monroe, LA, USA.
Clewell HJ; Ramboll US Corporation, Research Triangle Park, NC, USA.
Mundt KA; Cardno Chemrisk, Boston, MA, USA.
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Źródło:
Risk analysis : an official publication of the Society for Risk Analysis [Risk Anal] 2020 Feb; Vol. 40 (2), pp. 294-318. Date of Electronic Publication: 2019 Sep 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Carcinogenicity Tests*
Carcinogens*
Chloroprene/*adverse effects
Administration, Inhalation ; Animals ; Cricetinae ; Humans ; Kinetics ; Mice ; Models, Animal ; Rats ; Risk Assessment ; United States ; United States Environmental Protection Agency
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of heavy metal content in edible honeysuckle ( Lonicera japonica Thunb.) from China and health risk assessment.
Autorzy:
Fan L; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Chen L; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Cui W; College of Food Science and Engineering, Shandong Agricultural University, Taian, Shandong, China.
Dong Y; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Yuan X; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Wang L; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Liang J; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Zhao S; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
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Źródło:
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes [J Environ Sci Health B] 2020; Vol. 55 (10), pp. 921-928. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogenicity Tests*
Environmental Monitoring*
Lonicera/*chemistry
Metals, Heavy/*analysis
Soil Pollutants/*analysis
China ; Humans ; Risk Assessment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Carcinogenome Project: In Vitro Gene Expression Profiling of Chemical Perturbations to Predict Long-Term Carcinogenicity.
Autorzy:
Li A; 1 Computational Biomedicine, Boston University School of Medicine , Boston, Massachusetts, USA.; 2 Bioinformatics Program, Boston University , Boston, Massachusetts, USA.
Lu X; 3 Cancer Program, Broad Institute of MIT and Harvard , Cambridge, Massachusetts, USA.
Natoli T; 3 Cancer Program, Broad Institute of MIT and Harvard , Cambridge, Massachusetts, USA.
Bittker J; 3 Cancer Program, Broad Institute of MIT and Harvard , Cambridge, Massachusetts, USA.
Sipes NS; 4 Toxicoinformatics Group, National Institute of Environmental Health Sciences , Durham, North Carolina, USA.
Subramanian A; 3 Cancer Program, Broad Institute of MIT and Harvard , Cambridge, Massachusetts, USA.
Auerbach S; 4 Toxicoinformatics Group, National Institute of Environmental Health Sciences , Durham, North Carolina, USA.
Sherr DH; 5 Department of Environmental Health, Boston University School of Public Health , Boston, Massachusetts, USA.
Monti S; 1 Computational Biomedicine, Boston University School of Medicine , Boston, Massachusetts, USA.; 2 Bioinformatics Program, Boston University , Boston, Massachusetts, USA.
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Źródło:
Environmental health perspectives [Environ Health Perspect] 2019 Apr; Vol. 127 (4), pp. 47002.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinogenicity Tests/*methods
Carcinogens/*toxicity
Gene Expression Profiling/*methods
Toxicogenetics/*methods
Area Under Curve ; Carcinogenicity Tests/instrumentation ; DNA Damage ; Gene Expression Profiling/instrumentation ; Hep G2 Cells ; Humans ; In Vitro Techniques/instrumentation ; In Vitro Techniques/methods ; ROC Curve
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Central nervous system tumors in 2-year rat carcinogenicity studies: perspectives on human risk assessment.
Autorzy:
Sacaan A; Pfizer Inc. Drug Safety Research and Development.
Thibault S; Pfizer Inc. Drug Safety Research and Development.
Khan KN; Pfizer Inc. Drug Safety Research and Development.
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Źródło:
The Journal of toxicological sciences [J Toxicol Sci] 2019; Vol. 44 (10), pp. 643-655.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinogenicity Tests*
Risk Assessment*
Central Nervous System Neoplasms/*chemically induced
Glioma/*chemically induced
Animals ; Biological Assay ; Central Nervous System Neoplasms/classification ; Glioma/classification ; Humans ; Rats ; Species Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Is current risk assessment of non-genotoxic carcinogens protective?
Autorzy:
Braakhuis HM; a Centre for Health Protection , National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands.
Slob W; b Centre for Nutrition, Prevention and Health services , National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands.
Olthof ED; a Centre for Health Protection , National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands.
Wolterink G; b Centre for Nutrition, Prevention and Health services , National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands.
Zwart EP; a Centre for Health Protection , National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands.
Gremmer ER; a Centre for Health Protection , National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands.
Rorije E; c Centre for Safety of Substances and Products , National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands.
van Benthem J; a Centre for Health Protection , National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands.
Woutersen R; d Netherlands Organization for Applied Scientific Research (TNO) , Zeist , The Netherlands.
van der Laan JW; e Medicines Evaluation Board , Utrecht , The Netherlands.
Luijten M; a Centre for Health Protection , National Institute for Public Health and the Environment (RIVM) , Bilthoven , The Netherlands.
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Źródło:
Critical reviews in toxicology [Crit Rev Toxicol] 2018 Jul; Vol. 48 (6), pp. 500-511. Date of Electronic Publication: 2018 May 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinogenicity Tests/*methods
Carcinogens/*toxicity
Neoplasms/*chemically induced
Animals ; Carcinogenicity Tests/standards ; DNA Damage ; Female ; Humans ; Male ; No-Observed-Adverse-Effect Level ; Risk Assessment/methods ; Risk Assessment/standards
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In Vitro.
Autorzy:
Parfett CL; Mechanistic Studies Division, Environmental Health Science and Research Bureau,HealthyEnvironments and Consumer Safety Branch, Health Canada, 50 Columbine Driveway,Tunney's Pasture, Ottawa, ON K1A 0K9, Canada. .
Desaulniers D; Hazard Identification Division, Environmental Health Science and Research Bureau,HealthyEnvironments and Consumer Safety Branch, Health Canada, 50 Columbine Driveway,Tunney's Pasture, Ottawa, ON K1A 0K9, Canada. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2017 Jun 01; Vol. 18 (6). Date of Electronic Publication: 2017 Jun 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinogenicity Tests*
Epigenesis, Genetic*
Epigenomics*/methods
Adenosine Triphosphate/metabolism ; Animals ; CCCTC-Binding Factor/metabolism ; Carcinogens/pharmacology ; Carcinogens/toxicity ; Cell Transformation, Neoplastic/drug effects ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; DNA Methylation ; Gene Expression Regulation/drug effects ; Gene Silencing ; Histones/metabolism ; Humans ; Models, Biological ; Nucleosomes/genetics ; Nucleosomes/metabolism ; Protein Binding ; Protein Processing, Post-Translational ; RNA, Untranslated/genetics ; Risk Assessment ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Applicability of Scrape Loading-Dye Transfer Assay for Non-Genotoxic Carcinogen Testing.
Autorzy:
Sovadinová I; RECETOX, Faculty of Science, Masaryk University, 625-00 Brno, Czech Republic.
Upham BL; Department of Pediatrics and Human Development, Institute for Integrative Toxicology, Michigan State University, East Lansing, MI 48824, USA.
Trosko JE; Department of Pediatrics and Human Development, Institute for Integrative Toxicology, Michigan State University, East Lansing, MI 48824, USA.
Babica P; RECETOX, Faculty of Science, Masaryk University, 625-00 Brno, Czech Republic.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 20; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinogenicity Tests/*methods
Cell Communication/*physiology
Gap Junctions/*metabolism
Animals ; Biological Assay/methods ; Carcinogens ; Cell Communication/drug effects ; Cell Line ; Cells, Cultured ; Coloring Agents/metabolism ; Liver/pathology ; Microscopy, Fluorescence/methods ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Short-term carcinogenicity study of N-methyl-N-nitrosourea in FVB-Trp53 heterozygous mice.
Autorzy:
Kim, Na-Won (AUTHOR)
Seo, Sun-Min (AUTHOR)
Yoo, Eun-Seon (AUTHOR)
Kang, Ah-Reum (AUTHOR)
Lee, Ji-Hun (AUTHOR)
Lee, Jae-Hoon (AUTHOR)
Kang, Byeong-Cheol (AUTHOR)
Lee, Han-Woong (AUTHOR)
Choi, Yang-Kyu (AUTHOR)
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Źródło:
PLoS ONE. 1/6/2023, Vol. 17 Issue 1, p1-15. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multiple contrast type tests for the evaluation of animal carcinogenicity studies.
Autorzy:
Rahman M; a Division of Biometrics-6, Office of Biostatistics, Office of Translational Sciences , Center for Drug Evaluation and Research, US Food and Drug Administration , Silver Spring , Maryland , USA.
Tiwari R; b Intermediate Office, Office of Biostatistics, Office of Translational Sciences , Center for Drug Evaluation and Research, US Food and Drug Administration , Silver Spring , Maryland , USA.
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Źródło:
Journal of biopharmaceutical statistics [J Biopharm Stat] 2017; Vol. 27 (1), pp. 175-185. Date of Electronic Publication: 2016 Feb 18.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogenicity Tests*
Linear Models*
Neoplasms/*chemically induced
Animals ; Data Interpretation, Statistical ; Dose-Response Relationship, Drug ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans.
Autorzy:
Kuempel ED; a National Institute for Occupational Safety and Health , Cincinnati , OH , USA.
Jaurand MC; b Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche , UMR 1162 , Paris , France.; c Labex Immuno-Oncology, Sorbonne Paris Cité, University of Paris Descartes , Paris , France.; d University Institute of Hematology, Sorbonne Paris Cité, University of Paris Diderot , Paris , France.; e University of Paris 13, Sorbonne Paris Cité , Saint-Denis , France.
Møller P; f Department of Public Health , University of Copenhagen , Copenhagen , Denmark.
Morimoto Y; g Department of Occupational Pneumology , University of Occupational and Environmental Health , Kitakyushu City , Japan.
Kobayashi N; h National Institute of Health Sciences , Tokyo , Japan.
Pinkerton KE; i Center for Health and the Environment, University of California , Davis , California , USA.
Sargent LM; j National Institute for Occupational Safety and Health , Morgantown , West Virginia , USA.
Vermeulen RC; k Institute for Risk Assessment Sciences, Utrecht University , Utrecht , The Netherlands.
Fubini B; l Department of Chemistry and 'G.Scansetti' Interdepartmental Center , Università degli Studi di Torino , Torino , Italy.
Kane AB; m Department of Pathology and Laboratory Medicine , Brown University , Providence , RI , USA.
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Źródło:
Critical reviews in toxicology [Crit Rev Toxicol] 2017 Jan; Vol. 47 (1), pp. 1-58. Date of Electronic Publication: 2016 Aug 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinogenicity Tests*
Nanofibers/*toxicity
Nanotubes, Carbon/*toxicity
Animals ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The legacy of the F344 rat as a cancer bioassay model (a retrospective summary of three common F344 rat neoplasms).
Autorzy:
Maronpot RR; a Maronpot Consulting LLC , Raleigh , NC , USA ;
Nyska A; b Sackler School of Medicine, Tel Aviv University, and Consultant in Toxicologic Pathology , Timrat , Israel ;
Foreman JE; c ExxonMobil Biomedical Sciences, Inc , Annadale , NJ , USA ;
Ramot Y; d Hadassah-Hebrew University Medical Center , Jerusalem , Israel.
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Źródło:
Critical reviews in toxicology [Crit Rev Toxicol] 2016 Sep; Vol. 46 (8), pp. 641-75. Date of Electronic Publication: 2016 Jun 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Biological Assay*
Carcinogenicity Tests*
Models, Animal*
Rats, Inbred F344*
Animals ; Leukemia ; Leydig Cell Tumor ; Mesothelioma ; Rats ; Risk Assessment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An integrative test strategy for cancer hazard identification.
Autorzy:
Luijten M; a Centre for Health Protection, National Institute for Public Health and the Environment (RIVM) , Bilthoven , the Netherlands ;
Olthof ED; a Centre for Health Protection, National Institute for Public Health and the Environment (RIVM) , Bilthoven , the Netherlands ;
Hakkert BC; b Centre for Safety of Substances and Products, National Institute for Public Health and the Environment (RIVM) , Bilthoven , the Netherlands ;
Rorije E; b Centre for Safety of Substances and Products, National Institute for Public Health and the Environment (RIVM) , Bilthoven , the Netherlands ;
van der Laan JW; c Medicines Evaluation Board , Utrecht , the Netherlands ;
Woutersen RA; d Netherlands Organization for Applied Scientific Research (TNO) , Zeist , the Netherlands.
van Benthem J; a Centre for Health Protection, National Institute for Public Health and the Environment (RIVM) , Bilthoven , the Netherlands ;
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Źródło:
Critical reviews in toxicology [Crit Rev Toxicol] 2016 Aug; Vol. 46 (7), pp. 615-39. Date of Electronic Publication: 2016 May 03.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogenicity Tests/*methods
Animals ; Biological Assay ; Carcinogenicity Tests/standards ; Carcinogens/toxicity ; DNA Damage ; Humans ; Mutagenicity Tests/methods ; Mutagenicity Tests/standards ; Mutagens/toxicity ; Neoplasms ; Risk Assessment/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis.
Autorzy:
Smith MT; Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, California, USA.
Guyton KZ
Gibbons CF
Fritz JM
Portier CJ
Rusyn I
DeMarini DM
Caldwell JC
Kavlock RJ
Lambert PF
Hecht SS
Bucher JR
Stewart BW
Baan RA
Cogliano VJ
Straif K
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Źródło:
Environmental health perspectives [Environ Health Perspect] 2016 Jun; Vol. 124 (6), pp. 713-21. Date of Electronic Publication: 2015 Nov 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Carcinogenicity Tests/*methods
Carcinogens/*toxicity
Animals ; Benzene/toxicity ; Carcinogenesis ; Carcinogenicity Tests/standards ; Carcinogens/standards ; Humans ; Polychlorinated Biphenyls/toxicity ; Risk Assessment/methods ; Risk Assessment/standards
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A comprehensive analysis of the animal carcinogenicity data for glyphosate from chronic exposure rodent carcinogenicity studies.
Autorzy:
Portier CJ; Rollins School of Public Health, Emory University, Atlanta, GA, USA. .; Department of Toxicogenomics, Maastricht University, Maastricht, Netherlands. .; CJP Consulting, Seattle, Washington, USA. .
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Źródło:
Environmental health : a global access science source [Environ Health] 2020 Feb 12; Vol. 19 (1), pp. 18. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Carcinogenicity Tests/*statistics & numerical data
Glycine/*analogs & derivatives
Herbicides/*toxicity
Toxicity Tests, Chronic/*statistics & numerical data
Animals ; Glycine/toxicity ; Mice ; Rats ; Glyphosate
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hazard identification, classification, and risk assessment of carcinogens: too much or too little? - Report of an ECETOC workshop.
Autorzy:
Felter SP; Procter & Gamble, Mason, OH, USA.
Boobis AR; Imperial College London, London, UK.
Botham PA; Syngenta Jealott's Hill, Bracknell, UK.
Brousse A; European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC), Brussels, Belgium.
Greim H; Technical University of Munich, Munich, Germany.
Hollnagel HM; Dow Europe GmbH, Horgen, Switzerland.
Sauer UG; Scientific Consultancy - Animal Welfare, Neubiberg, Germany.
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Źródło:
Critical reviews in toxicology [Crit Rev Toxicol] 2020 Jan; Vol. 50 (1), pp. 72-95. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Carcinogenicity Tests/*methods
Carcinogens/*toxicity
Carcinogens/classification ; Ecotoxicology ; Humans ; Risk Assessment/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cross-platform toxicogenomics for the prediction of non-genotoxic hepatocarcinogenesis in rat.
Autorzy:
Römer M; Center of Bioinformatics Tuebingen (ZBIT), University of Tuebingen, Tübingen, Germany.
Eichner J; Center of Bioinformatics Tuebingen (ZBIT), University of Tuebingen, Tübingen, Germany.
Metzger U; Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.
Templin MF; Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.
Plummer S; CXR Biosciences, James Lindsay Place, Dundee Technopole, Dundee, Scotland, United Kingdom.
Ellinger-Ziegelbauer H; Bayer Pharma AG, Wuppertal, Germany.
Zell A; Center of Bioinformatics Tuebingen (ZBIT), University of Tuebingen, Tübingen, Germany.
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Źródło:
PloS one [PLoS One] 2014 May 15; Vol. 9 (5), pp. e97640. Date of Electronic Publication: 2014 May 15 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinogenicity Tests*
Carcinogens/*chemistry
Liver Neoplasms, Experimental/*metabolism
Toxicogenetics/*methods
Algorithms ; Animals ; Area Under Curve ; Artificial Intelligence ; Cluster Analysis ; Computational Biology ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Liver Neoplasms, Experimental/chemically induced ; Male ; Models, Statistical ; Protein Array Analysis ; RNA, Messenger/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 1835

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