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Wyświetlanie 1-20 z 79765
Tytuł:
Identification of RNF150 as the hub gene associated with microsatellite instability in gastric cancer.
Autorzy:
Pan J; Department of Gastroenterology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.
Lan Q; Department of Pathology, Renmin Hospital, Wuhan University, Wuhan, 430060, Hubei, China.
Li S; Department of Gastroenterology, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 01; Vol. 13 (1), pp. 12495. Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Stomach Neoplasms*/pathology
Humans ; Microsatellite Repeats/genetics ; Membrane Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
COSAP: Comparative Sequencing Analysis Platform.
Autorzy:
Ergun MA; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.
Cinal O; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.
Bakışlı B; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.
Emül AA; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey.
Baysan M; Department of Computer Engineering, Istanbul Technical University, 34469, Istanbul, Turkey. .
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2024 Mar 26; Vol. 25 (1), pp. 130. Date of Electronic Publication: 2024 Mar 26.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Copy Number Variations*
Microsatellite Instability*
Humans ; Reproducibility of Results ; High-Throughput Nucleotide Sequencing/methods ; Software
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques.
Autorzy:
Deycmar S; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Roche Postdoctoral Fellowship (RPF) Program, Basel, Switzerland.
Johnson BJ; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Ray K; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Schaaf GW; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Ryan DP; School of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Cullin C; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Dozier BL; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Ferguson B; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Bimber BN; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, USA.
Olson JD; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Caudell DL; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Whitlow CT; Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Solingapuram Sai KK; Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Romero EC; New Iberia Research Center, University of Louisiana-Lafayette, New Iberia, LA, USA.
Villinger FJ; New Iberia Research Center, University of Louisiana-Lafayette, New Iberia, LA, USA.
Burgos AG; Caribbean Primate Research Center, University of Puerto Rico, Toa Baja, PR, USA.
Ainsworth HC; Department of Biostatistics and Data Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Miller LD; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Center for Cancer Genomics and Precision Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Hawkins GA; Center for Cancer Genomics and Precision Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Chou JW; Center for Cancer Genomics and Precision Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Gomes B; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
Hettich M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.
Ceppi M; Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.; iTeos Therapeutics, Translational Medicine, Gosselies, Belgium.
Charo J; Roche Pharma Research and Early Development, Roche Innovation Center Zurich, Zurich, Switzerland.
Cline JM; Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 19; Vol. 22 (1), pp. 292. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/pathology
Brain Neoplasms*
Neoplastic Syndromes, Hereditary*
Humans ; Animals ; Macaca mulatta/genetics ; Macaca mulatta/metabolism ; MutL Protein Homolog 1/genetics ; Mismatch Repair Endonuclease PMS2/genetics ; Mismatch Repair Endonuclease PMS2/metabolism ; DNA Methylation/genetics ; Epigenesis, Genetic ; Transcription Factors/genetics ; Transcription Factors/metabolism ; DNA/metabolism ; DNA Mismatch Repair/genetics
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Helicobacter pylori and Epstein-Barr Virus Co-Infection in Gastric Disease: What Is the Correlation with p53 Mutation , Genes Methylation and Microsatellite Instability in a Cohort of Sicilian Population?
Autorzy:
Giammanco A; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Anzalone R; Department of Surgical Oncological and Oral Sciences, University of Palermo, 90133 Palermo, Italy.
Serra N; Department of Public Health, University Federico II of Naples, 80138 Napoli, Italy.
Graceffa G; Department of Surgical Oncological and Oral Sciences, University of Palermo, 90133 Palermo, Italy.
Vieni S; Department of Surgical Oncological and Oral Sciences, University of Palermo, 90133 Palermo, Italy.
Scibetta N; Anatomopathology Unit, Arnas Civico Di Cristina Benfratelli Hospital, 90127 Palermo, Italy.
Rea T; Public Health Department, Federico II University Hospital, 80131 Naples, Italy.
Capra G; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Fasciana T; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 30; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 30.
Typ publikacji:
Journal Article
MeSH Terms:
Helicobacter Infections*/complications
Epstein-Barr Virus Infections*/complications
Stomach Diseases*/genetics
Stomach Diseases*/microbiology
Stomach Diseases*/virology
Genes, p53*/genetics
DNA Methylation*
Microsatellite Instability*
Helicobacter pylori ; Herpesvirus 4, Human ; Coinfection ; Mutation ; Sicily ; Humans ; Male ; Female ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Logistic Models
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Single-cell sequencing reveals the immune microenvironment landscape related to anti-PD-1 resistance in metastatic colorectal cancer with high microsatellite instability.
Autorzy:
Wu T; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Zhang X; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Liu X; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Cai X; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Shen T; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Pan D; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Liang R; College of Bioengineering, Chongqing University, Chongqing, China.
Ding R; Department of Minimally Invasive Intervention, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Hu R; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Dong J; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Li F; Department of Gastroenteroscopy, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Li J; Department of Gastroenteroscopy, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Xie L; Department of Oncology, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Wang C; Department of Radiology, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.
Geng S; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Yang Z; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China.
Xing L; Department of Dermatology, Kunming Children's Hospital, Kunming, China. .
Li Y; Department of Colorectal Surgery, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, No. 519, Kunzhou Road, Xishan District, Kunming, 650118, China. .
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Źródło:
BMC medicine [BMC Med] 2023 Apr 27; Vol. 21 (1), pp. 161. Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Animals ; Mice ; CD8-Positive T-Lymphocytes/pathology ; Immunohistochemistry ; Tumor Microenvironment
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours.
Autorzy:
Geurts BS; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
Battaglia TW; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
van Berge Henegouwen JM; Oncode Institute, Utrecht, the Netherlands.; Department of Medical Oncology, Leiden University Medical Centre, Leiden, the Netherlands.
Zeverijn LJ; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
de Wit GF; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
Hoes LR; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
van der Wijngaart H; Oncode Institute, Utrecht, the Netherlands.; Department of Medical Oncology, Amsterdam University Medical Centre, location VUMC, Amsterdam, the Netherlands.
van der Noort V; Department of Biometrics, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Roepman P; Hartwig Medical Foundation, Amsterdam, the Netherlands.
de Leng WWJ; Department of Pathology, University Medical Cancer Centre Utrecht, Utrecht, the Netherlands.
Jansen AML; Department of Pathology, University Medical Cancer Centre Utrecht, Utrecht, the Netherlands.
Opdam FL; Department of Clinical Pharmacology, the Netherlands Cancer Institute, Amsterdam, the Netherlands.
de Jonge MJA; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Cirkel GA; Department of Medical Oncology, Meander, Amersfoort, the Netherlands.
Labots M; Department of Medical Oncology, Amsterdam University Medical Centre, location VUMC, Amsterdam, the Netherlands.
Hoeben A; Department of Medical Oncology, Department of Internal Medicine, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Kerver ED; Department of Medical Oncology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
Bins AD; Department of Medical Oncology, Amsterdam University Medical Centre, location AUMC, Amsterdam, the Netherlands.
Erdkamp FGL; Department of Medical Oncology, Zuyderland Hospital, Sittard-Geelen, the Netherlands.
van Rooijen JM; Department of Medical Oncology, Martini Hospital, Groningen, the Netherlands.
Houtsma D; Department of Medical Oncology, Haga Hospital, The Hague, the Netherlands.
Hendriks MP; Department of Medical Oncology, Northwest Clinics, Alkmaar, the Netherlands.
de Groot JB; Department of Medical Oncology, Isala, Zwolle, the Netherlands.
Verheul HMW; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Gelderblom H; Department of Medical Oncology, Leiden University Medical Centre, Leiden, the Netherlands.
Voest EE; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. .; Oncode Institute, Utrecht, the Netherlands. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Mar 04; Vol. 23 (1), pp. 205. Date of Electronic Publication: 2023 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Brain Neoplasms*
Humans ; Biomarkers
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Diagnostic Performance of Immunohistochemistry Compared to Molecular Techniques for Microsatellite Instability and p53 Mutation Detection in Endometrial Cancer.
Autorzy:
Streel S; Department of Medical Oncology, CHU Liège, 4000 Liège, Belgium.
Salmon A; Department of Medical Oncology, CHU Liège, 4000 Liège, Belgium.
Dheur A; Department of Gynecology and Obstetrics, CHU Liège, 4000 Liège, Belgium.
Bours V; Department of Human Genetics, CHU Liège, 4000 Liège, Belgium.
Leroi N; Department of Human Genetics, CHU Liège, 4000 Liège, Belgium.
Habran L; Department of Pathology, CHU Liège, 4000 Liège, Belgium.
Delbecque K; Department of Pathology, CHU Liège, 4000 Liège, Belgium.
Goffin F; Department of Gynecology and Obstetrics, CHU Liège, 4000 Liège, Belgium.
Pleyers C; Department of Radiotherapy Oncology, CHU Liège, 4000 Liège, Belgium.
Kakkos A; Department of Gynecology and Obstetrics, CHU Liège, 4000 Liège, Belgium.
Gonne E; Department of Medical Oncology, CHU Liège, 4000 Liège, Belgium.
Seidel L; Department of Biostatistics, CHU Liège, 4000 Liège, Belgium.
Kridelka F; Department of Gynecology and Obstetrics, CHU Liège, 4000 Liège, Belgium.
Gennigens C; Department of Medical Oncology, CHU Liège, 4000 Liège, Belgium.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 02; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Endometrial Neoplasms*/genetics
Female ; Humans ; Tumor Suppressor Protein p53/genetics ; Immunohistochemistry ; Mutation ; DNA Mismatch Repair
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
DeltaMSI: artificial intelligence-based modeling of microsatellite instability scoring on next-generation sequencing data.
Autorzy:
Swaerts K; Department of Laboratory Medicine, AZ Delta General Hospital, Deltalaan 1, 8800, Roeselare, Belgium.; RADar Innovation Center, AZ Delta General Hospital, Roeselare, Belgium.
Dedeurwaerdere F; Department of Pathology, AZ Delta General Hospital, Roeselare, Belgium.
De Smet D; Department of Laboratory Medicine, AZ Delta General Hospital, Deltalaan 1, 8800, Roeselare, Belgium.; RADar Innovation Center, AZ Delta General Hospital, Roeselare, Belgium.
De Jaeger P; RADar Innovation Center, AZ Delta General Hospital, Roeselare, Belgium.
Martens GA; Department of Laboratory Medicine, AZ Delta General Hospital, Deltalaan 1, 8800, Roeselare, Belgium. .; RADar Innovation Center, AZ Delta General Hospital, Roeselare, Belgium. .; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium. .
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2023 Mar 01; Vol. 24 (1), pp. 73. Date of Electronic Publication: 2023 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Artificial Intelligence*
Humans ; Microsatellite Repeats ; High-Throughput Nucleotide Sequencing ; Machine Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Establishment of a gastric cancer cell line with high microsatellite instability, OCUM-13, derived from Borrmann type-2 primary tumor.
Autorzy:
Yamamoto Y; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Masuda G; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Kushiyama S; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Maruo K; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Tsujio G; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Sera T; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Sugimoto A; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Nishimura S; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Kuroda K; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Togano S; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Okuno T; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Ohira M; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Yashiro M; Molecular Oncology and Therapeutics, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Cancer Center for Translational Research, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.; Department of Gastroenterological Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2023 Mar; Vol. 12 (5), pp. 6016-6022. Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Stomach Neoplasms*/pathology
Animals ; Mice ; Microsatellite Repeats ; Cell Line, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High concordance rate of capillary electrophoresis workflow for microsatellite instability analysis and mismatch repair (MMR) immunostaining in colorectal carcinoma.
Autorzy:
Huang W; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ho CL; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Lee CT; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen WL; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
Yang SC; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
Chow NH; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen YL; Department of Pathology, Molecular Diagnosis Laboratory, National Cheng Kung University Hospital, Tainan, Taiwan.; Molecular Medicine Core Laboratory, Research Center of Clinical Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
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Źródło:
PloS one [PLoS One] 2023 Apr 25; Vol. 18 (4), pp. e0284227. Date of Electronic Publication: 2023 Apr 25 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/diagnosis
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Humans ; DNA Mismatch Repair/genetics ; Workflow ; Microsatellite Repeats/genetics ; DNA-Binding Proteins/genetics ; Electrophoresis, Capillary ; MutL Protein Homolog 1/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development and Interpretation of a Clinicopathological-Based Model for the Identification of Microsatellite Instability in Colorectal Cancer.
Autorzy:
Jiang Z; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Yan L; Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Deng S; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Gu J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Qin L; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.; Department of General Surgery, First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, Xinjiang 832008, China.
Mao F; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Xue Y; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Cai W; College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Nie X; Department of Pathology, Union Hospital, Tongji Medical, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Liu H; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Shang F; Department of Medical Oncology, Nanyang Central Hospital, Nanyang, Henan, China.
Tao K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Wang J; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Wu K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
Cao Y; Department of Digestive Surgical Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Cai K; Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
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Źródło:
Disease markers [Dis Markers] 2023 Feb 18; Vol. 2023, pp. 5178750. Date of Electronic Publication: 2023 Feb 18 (Print Publication: 2023).
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/genetics
Humans ; Bayes Theorem ; Retrospective Studies ; Area Under Curve
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An association between ATP7B expression and human cancer prognosis and immunotherapy: a pan-cancer perspective.
Autorzy:
Zhang Z; Department of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Xinhua District, Shijiazhuang, Hebei Province, China.
Zhang A; Department of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Xinhua District, Shijiazhuang, Hebei Province, China.
Shi Y; Department of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Xinhua District, Shijiazhuang, Hebei Province, China.
Zhao Z; Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, No. 50, a pine in Xiangshan, Haidian District, Beijing, China.
Zhao Z; Department of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Xinhua District, Shijiazhuang, Hebei Province, China. .; Department of Neurosurgery, The Fourth Hospital of Hebei Medical University, No. 12 Jiankang Road, Chang'an District, Shijiazhuang, Hebei Province, China. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 Nov 30; Vol. 16 (1), pp. 307. Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Neoplasms*/genetics
Neoplasms*/therapy
Humans ; Immunotherapy ; Adjuvants, Immunologic ; Databases, Factual ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetic profile of Chinese patients with small bowel cancer categorized by anatomic location.
Autorzy:
Shi C; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, No 295, Xichang Road, Kunming, Yunnan Province, 650032, P.R. China.
Ma J; School of Nursing, Yunnan University of Traditional Chinese Medicines, Kunming, Yunnan, 650504, P.R. China.
Zhang T; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, No 295, Xichang Road, Kunming, Yunnan Province, 650032, P.R. China.
Shi Y; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, No 295, Xichang Road, Kunming, Yunnan Province, 650032, P.R. China.
Duan W; The Medical Department, 3D Medicines Inc., Building 2, Block B, 158 XinJunhuan Street, Pujiang Hi-Tech Park, MinHang District, Shanghai, 201114, P.R. China.
Huang D; The Medical Department, 3D Medicines Inc., Building 2, Block B, 158 XinJunhuan Street, Pujiang Hi-Tech Park, MinHang District, Shanghai, 201114, P.R. China.
Zhang H; The Medical Department, 3D Medicines Inc., Building 2, Block B, 158 XinJunhuan Street, Pujiang Hi-Tech Park, MinHang District, Shanghai, 201114, P.R. China. .; Zhaotong Health Vocational College, Zhaotong, Yunnan, 657000, P.R. China. .
Zeng Y; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, No 295, Xichang Road, Kunming, Yunnan Province, 650032, P.R. China. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 Nov 16; Vol. 16 (1), pp. 289. Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microsatellite Instability*
Colorectal Neoplasms*/genetics
Humans ; East Asian People ; Genetic Profile ; Mutation ; Biomarkers, Tumor/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of Microsatellite Instability as Pan-Cancer Agnostic Marker of Solid Tumours in Personalized Medicine
Autorzy:
Kaler, Amrit KaurAff1, IDs43152024000545_cor1
Fatima, Sheereen
Dhurat, Omkar
Rane, Samrudhi
Limaye, Shweta
Umarji, Smitha
Tiwarekar, Yash
Nikam, Ankita
Kulkarni, Bijal
Athikari, Nevitha
Shaikh, Imran
Goyle, Sandeep
Mulchandani, Manoj
Kulkarni, Yogesh
Mistry, Rajesh
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Źródło:
Current Tissue Microenvironment Reports. :1-9
Czasopismo naukowe
Szczegóły
Tytuł:
BAT26 Only Microsatellite Instability with High Tumor Mutation Burden-A Rare Entity Associated with PTEN Protein Loss and High PD-L1 Expression.
Autorzy:
Kang SY; Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Kim DG; Department of Clinical Genomic Center, Samsung Medical Center, Seoul 06351, Korea.; Department of Digital Health, Samsung Advanced Institute of Health Science and Technology, Sungkyunkwan University, Seoul 06351, Korea.
Kim KM; Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.; Center of Companion Diagnostics, Samsung Medical Center, Seoul 06351, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 14; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/metabolism
Microsatellite Instability*
B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Biomarkers, Tumor/genetics ; Female ; Humans ; Ligands ; Microsatellite Repeats ; Mismatch Repair Endonuclease PMS2/genetics ; Mutation ; PTEN Phosphohydrolase/genetics ; PTEN Phosphohydrolase/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics ; Tensins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microsatellite instability-high is rare events in refractory pediatric solid tumors.
Autorzy:
Yoshida T; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Muramatsu H; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Wakamatsu M; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Taniguchi R; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ichikawa D; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nakaguro M; Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
Natsume A; Nagoya University, The Institute of Innovation for Future Society NIC Room 803, Furo-Cho, Chikusa-Ku, Nagoya, 464-8601, Japan.; Kawamura Medical Associates, Gifu, 501-3144, Japan.
Takahashi Y; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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Źródło:
Pediatric hematology and oncology [Pediatr Hematol Oncol] 2022 Aug; Vol. 39 (5), pp. 468-474. Date of Electronic Publication: 2021 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Neoplasms*/genetics
Child ; DNA Mismatch Repair ; Humans ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Real-world study on microsatellite instability and mismatch repair deficiency testing patterns among patients with metastatic colorectal cancer in Spain
Autorzy:
Garcia-Carbonero, RocioAff1, IDs1209402303309z_cor1
González Astorga, Beatriz
Vidal Tocino, Rosario
Contreras Toledo, Débora
Pericay, Carles
Fernández Montes, Ana
Falcó, Esther
González Cordero, Marta
Reina Zoilo, Juan José
Alonso, Vicente
Rodríguez Salas, Nuria
Gil-Raga, Mireia
Santos, Cristina
Páez, David
Anton-Pascual, Beatriz
Aguilar, FernandoAff15, IDs1209402303309z_cor16
Morales, Pilar
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Źródło:
Clinical and Translational Oncology. 26(4):864-871
Czasopismo naukowe
Szczegóły
Tytuł:
Mismatch Repair and Microsatellite Instability Testing for Immune Checkpoint Inhibitor Therapy: Guideline From the College of American Pathologists in Collaboration With the Association for Molecular Pathology and Fight Colorectal Cancer.
Autorzy:
Bartley AN; From the Department of Pathology, St. Joseph Mercy Hospital, Ann Arbor, Michigan (Bartley).
Mills AM; From the Department of Pathology, University of Virginia, Charlottesville (Mills).
Konnick E; From the Department of Laboratory Medicine and Pathology, University of Washington, Seattle (Konnick).
Overman M; From the Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston (Overman).
Ventura CB; From Surveys, College of American Pathologists, Northfield, Illinois (Ventura, Colasacco).
Souter L; From Methodology Consultant, Smithville, Ontario, Canada (Souter).
Colasacco C; From Surveys, College of American Pathologists, Northfield, Illinois (Ventura, Colasacco).
Stadler ZK; From the Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York (Stadler).
Kerr S; From Hospital Pathology Associates, PA, Minneapolis, Minnesota (Kerr).
Howitt BE; From the Department of Pathology, Stanford University, Stanford, California (Howitt).
Hampel H; From the Department of Internal Medicine, The Ohio State University, Columbus (Hampel).
Adams SF; From the Department of Obstetrics & Gynecology, University of New Mexico, Albuquerque (Adams).
Johnson W; From Fight Colorectal Cancer, Springfield, Missouri (Johnson).
Magi-Galluzzi C; From the Department of Pathology, University of Alabama at Birmingham, Birmingham (Magi-Galluzzi).
Sepulveda AR; From the Department of Pathology, George Washington University, Washington, District of Columbia (Sepulveda).
Broaddus RR; From the Department of Pathology & Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill (Broaddus).
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2022 Oct 01; Vol. 146 (10), pp. 1194-1210.
Typ publikacji:
Journal Article; Practice Guideline
MeSH Terms:
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Microsatellite Instability*
Female ; Humans ; DNA Mismatch Repair/genetics ; Immune Checkpoint Inhibitors ; Pathologists ; Pathology, Molecular/methods ; Systematic Reviews as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Human neural stem cells drug product: Microsatellite instability analysis.
Autorzy:
Grespi V; S. Maria Hospital Terni, Terni, Italy.
Caprera C; S. Maria Hospital Terni, Terni, Italy.
Ricciolini C; IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
Bicchi I; S. Maria Hospital Terni, Terni, Italy.
Muzi G; S. Maria Hospital Terni, Terni, Italy.
Corsi M; S. Maria Hospital Terni, Terni, Italy.
Ascani S; S. Maria Hospital Terni, Terni, Italy.
Vescovi AL; IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
Gelati M; IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
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Źródło:
PloS one [PLoS One] 2022 Aug 30; Vol. 17 (8), pp. e0273679. Date of Electronic Publication: 2022 Aug 30 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Neural Stem Cells*
Cell Differentiation ; Humans ; Stem Cell Transplantation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 79765

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