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Wyświetlanie 1-20 z 20789
Tytuł:
In Vitro Analyses of Spinach-Derived Opioid Peptides, Rubiscolins: Receptor Selectivity and Intracellular Activities through G Protein- and β-Arrestin-Mediated Pathways.
Autorzy:
Karasawa Y; Department of Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.; Department of Pain Control Research, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.; Medical Affairs, Viatris Pharmaceuticals Japan Inc., 5-11-2, Toranomon, Minato-ku, Tokyo 105-0001, Japan.
Miyano K; Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Fujii H; Laboratory of Medicinal Chemistry and Medicinal Research Laboratories, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Mizuguchi T; Laboratory of Medicinal Chemistry and Medicinal Research Laboratories, School of Pharmacy, Kitasato University, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Kuroda Y; Department of Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.; Department of Pain Control Research, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.; Department of Anesthesiology and Pain Medicine, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Nonaka M; Department of Pain Control Research, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.
Komatsu A; Department of Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.; Department of Pain Control Research, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.; Department of Anesthesiology and Pain Medicine, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Ohshima K; Department of Pain Control Research, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.
Yamaguchi M; Department of Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.; Department of Pain Control Research, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.; Medical Affairs, Pfizer Japan Inc., 3-22-7, Yoyogi, Shibuya-ku, Tokyo 151-0053, Japan.
Yamaguchi K; Department of Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.; Department of Anesthesiology and Pain Medicine, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Iseki M; Department of Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.; Department of Anesthesiology and Pain Medicine, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Uezono Y; Department of Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.; Department of Pain Control Research, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan.
Hayashida M; Department of Pain Medicine, Juntendo University Graduate School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.; Department of Anesthesiology and Pain Medicine, Faculty of Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Oct 08; Vol. 26 (19). Date of Electronic Publication: 2021 Oct 08.
Typ publikacji:
Journal Article
MeSH Terms:
Opioid Peptides/*pharmacology
Receptors, Opioid, delta/*agonists
Signal Transduction/*drug effects
Spinacia oleracea/*chemistry
GTP-Binding Proteins/metabolism ; Gene Expression Regulation/drug effects ; HEK293 Cells ; Humans ; Molecular Structure ; Opioid Peptides/chemistry ; Peptide Fragments/chemistry ; Peptide Fragments/pharmacology ; Receptors, Opioid, mu/metabolism ; Ribulose-Bisphosphate Carboxylase/chemistry ; Ribulose-Bisphosphate Carboxylase/pharmacology ; beta-Arrestins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Signaling Mechanism of Remote Postconditioning of the Heart: Prospects of the Use of Remote Postconditioning for the Treatment of Acute Myocardial Infarction.
Autorzy:
Ryabov, Vyacheslav V. (AUTHOR)
Vyshlov, Evgenii V. (AUTHOR)
Maslov, Leonid N. (AUTHOR)
Mukhomedzyanov, Alexandr V. (AUTHOR)
Naryzhnaya, Natalia V. (AUTHOR)
Boshchenko, Alla A. (AUTHOR)
Gombozhapova, Aleksandra E. (AUTHOR)
Samoylova, Julia O. (AUTHOR)
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Źródło:
Cells (2073-4409). Jun2023, Vol. 12 Issue 12, p1622. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reassessing the adrenomedullin scavenging function of ACKR3 in lymphatic endothelial cells.
Autorzy:
Sigmund, Elena C. (AUTHOR)
Bauer, Aline (AUTHOR)
Jakobs, Barbara D. (AUTHOR)
Tatliadim, Hazal (AUTHOR)
Tacconi, Carlotta (AUTHOR)
Thelen, Marcus (AUTHOR)
Legler, Daniel F. (AUTHOR)
Halin, Cornelia (AUTHOR)
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Źródło:
PLoS ONE. 5/30/2023, Vol. 17 Issue 5, p1-22. 22p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
IL-10/β-Endorphin-Mediated Neuroimmune Modulation on Microglia during Antinociception.
Autorzy:
Belo, Thiago Caetano Andrade (AUTHOR)
Santos, Gabriela Xavier (AUTHOR)
da Silva, Bruno Eduardo Gabriel (AUTHOR)
Rocha, Bruno Lopes Gonçalves (AUTHOR)
Abdala, Dennis William (AUTHOR)
Freire, Larissa Alves Moreira (AUTHOR)
Rocha, Fernanda Santos (AUTHOR)
Galdino, Giovane (AUTHOR)
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Źródło:
Brain Sciences (2076-3425). May2023, Vol. 13 Issue 5, p789. 11p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Peptidomimetics and Their Applications for Opioid Peptide Drug Discovery.
Autorzy:
Lee YS; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA.
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Źródło:
Biomolecules [Biomolecules] 2022 Sep 05; Vol. 12 (9). Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Opioid Peptides*/chemistry
Opioid Peptides*/pharmacology
Opioid Peptides*/therapeutic use
Peptidomimetics*/pharmacology
Peptidomimetics*/therapeutic use
Analgesics, Opioid/metabolism ; Analgesics, Opioid/pharmacology ; Analgesics, Opioid/therapeutic use ; Drug Discovery ; Receptors, Opioid
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antinociceptive and Cytotoxic Activity of Opioid Peptides with Hydrazone and Hydrazide Moieties at the C-Terminus.
Autorzy:
Dyniewicz J; Department of Neuropeptides, Mossakowski Medical Research Centre Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Lipiński PFJ; Department of Neuropeptides, Mossakowski Medical Research Centre Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Kosson P; Toxicology Research Laboratory, Mossakowski Medical Research Centre Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Bochyńska-Czyż M; Department of Neuropeptides, Mossakowski Medical Research Centre Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Matalińska J; Department of Neuropeptides, Mossakowski Medical Research Centre Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.
Misicka A; Department of Neuropeptides, Mossakowski Medical Research Centre Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland.; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Jul 28; Vol. 25 (15). Date of Electronic Publication: 2020 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Analgesics*/chemical synthesis
Analgesics*/chemistry
Analgesics*/pharmacology
Cytotoxins*/chemical synthesis
Cytotoxins*/chemistry
Cytotoxins*/pharmacology
Molecular Docking Simulation*
Opioid Peptides*/chemical synthesis
Opioid Peptides*/chemistry
Opioid Peptides*/pharmacology
Hydrazones/*chemistry
Melanoma/*drug therapy
Animals ; Cell Line, Tumor ; Humans ; Male ; Melanoma/metabolism ; Melanoma/pathology ; Rats ; Rats, Wistar ; Receptors, Opioid, mu/agonists ; Receptors, Opioid, mu/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protective Role and Functional Engineering of Neuropeptides in Depression and Anxiety: An Overview.
Autorzy:
Okdeh, Nathalie (AUTHOR)
Mahfouz, Georges (AUTHOR)
Harb, Julien (AUTHOR)
Sabatier, Jean-Marc (AUTHOR)
Roufayel, Rabih (AUTHOR)
Gazo Hanna, Eddie (AUTHOR)
Kovacic, Hervé (AUTHOR)
Fajloun, Ziad (AUTHOR)
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Źródło:
Bioengineering (Basel). Feb2023, Vol. 10 Issue 2, p258. 26p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Endogenous Opioid Peptides and Alternatively Spliced Mu Opioid Receptor Seven Transmembrane Carboxyl-Terminal Variants.
Autorzy:
Abrimian A; Department of Anesthesiology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Kraft T; Department of Anesthesiology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Pan YX; Department of Anesthesiology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 06; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alternative Splicing*
Opioid Peptides/*metabolism
RNA Precursors/*metabolism
Receptors, Opioid, mu/*metabolism
Animals ; Humans ; Protein Isoforms/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Endogenous Opioids and Their Role in Stem Cell Biology and Tissue Rescue.
Autorzy:
Petrocelli G; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.
Pampanella L; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.
Abruzzo PM; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.
Ventura C; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.; National Laboratory of Molecular Biology and Stem Cell Bioengineering of the National Institute of Biostructures and Biosystems (NIBB)-Eldor Lab, at the Innovation Accelerator, CNR, Via Piero Gobetti 101, 40129 Bologna, Italy.
Canaider S; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.; National Laboratory of Molecular Biology and Stem Cell Bioengineering of the National Institute of Biostructures and Biosystems (NIBB)-Eldor Lab, at the Innovation Accelerator, CNR, Via Piero Gobetti 101, 40129 Bologna, Italy.
Facchin F; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.; National Laboratory of Molecular Biology and Stem Cell Bioengineering of the National Institute of Biostructures and Biosystems (NIBB)-Eldor Lab, at the Innovation Accelerator, CNR, Via Piero Gobetti 101, 40129 Bologna, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Mar 30; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Analgesics, Opioid*/metabolism
Opioid Peptides*/metabolism
Humans ; Receptors, Opioid/metabolism ; Receptors, Opioid, kappa/metabolism ; Stem Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Food-Derived Opioid Peptides in Human Health: A Review.
Autorzy:
Tyagi A; Department of Food Science and Biotechnology, College of Agriculture and Life Sciences, Kangwon National University, Chuncheon 200-701, Korea.
Daliri EB; Department of Food Science and Biotechnology, College of Agriculture and Life Sciences, Kangwon National University, Chuncheon 200-701, Korea.
Kwami Ofosu F; Department of Food Science and Biotechnology, College of Agriculture and Life Sciences, Kangwon National University, Chuncheon 200-701, Korea.
Yeon SJ; Department of Food Science and Biotechnology, College of Agriculture and Life Sciences, Kangwon National University, Chuncheon 200-701, Korea.
Oh DH; Department of Food Science and Biotechnology, College of Agriculture and Life Sciences, Kangwon National University, Chuncheon 200-701, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 21; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Anxiety/*prevention & control
Depression/*prevention & control
Opioid Peptides/*therapeutic use
Stress Disorders, Traumatic, Acute/*prevention & control
Anxiety/pathology ; Delivery of Health Care ; Depression/pathology ; Humans ; Stress Disorders, Traumatic, Acute/pathology ; Western World
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Duration and Dose–Response Relationship of the Analgesic Action of the Tetrapeptide H-Tyr-D-Arg-Phe-Gly-NH2 (Taphalgin), a Synthetic Derivative of Dermorphine, in Comparison with Morphine Hydrochloride.
Autorzy:
Ivanova, E. A. (AUTHOR)
Voronina, T. A. (AUTHOR)
Korobov, N. V. (AUTHOR)
Kosorukov, V. S. (AUTHOR)
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Źródło:
Pharmaceutical Chemistry Journal. Dec2022, Vol. 56 Issue 9, p1164-1168. 5p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analgesia during Parturition in Domestic Animals: Perspectives and Controversies on Its Use.
Autorzy:
Mota-Rojas, Daniel (AUTHOR)
Velarde, Antonio (AUTHOR)
Marcet-Rius, Míriam (AUTHOR)
Orihuela, Agustín (AUTHOR)
Bragaglio, Andrea (AUTHOR)
Hernández-Ávalos, Ismael (AUTHOR)
Casas-Alvarado, Alejandro (AUTHOR)
Domínguez-Oliva, Adriana (AUTHOR)
Whittaker, Alexandra L. (AUTHOR)
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Źródło:
Animals (2076-2615). Oct2022, Vol. 12 Issue 19, p2686. 16p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of Nociceptin/Orphanin FQ-NOP Receptor System in the Regulation of Stress-Related Disorders.
Autorzy:
Ubaldi M; School of Pharmacy, University of Camerino, Via Madonna Delle Carceri 9, 62032 Camerino, Italy.
Cannella N; School of Pharmacy, University of Camerino, Via Madonna Delle Carceri 9, 62032 Camerino, Italy.
Borruto AM; School of Pharmacy, University of Camerino, Via Madonna Delle Carceri 9, 62032 Camerino, Italy.
Petrella M; School of Pharmacy, University of Camerino, Via Madonna Delle Carceri 9, 62032 Camerino, Italy.
Micioni Di Bonaventura MV; School of Pharmacy, University of Camerino, Via Madonna Delle Carceri 9, 62032 Camerino, Italy.
Soverchia L; School of Pharmacy, University of Camerino, Via Madonna Delle Carceri 9, 62032 Camerino, Italy.
Stopponi S; School of Pharmacy, University of Camerino, Via Madonna Delle Carceri 9, 62032 Camerino, Italy.
Weiss F; Department of Molecular and Cellular Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA.
Cifani C; School of Pharmacy, University of Camerino, Via Madonna Delle Carceri 9, 62032 Camerino, Italy.
Ciccocioppo R; School of Pharmacy, University of Camerino, Via Madonna Delle Carceri 9, 62032 Camerino, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 30; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Opioid Peptides/*physiology
Receptors, Opioid/*physiology
Stress, Physiological/*physiology
Animals ; Anxiety Disorders/drug therapy ; Anxiety Disorders/physiopathology ; Brain/drug effects ; Brain/physiopathology ; Feeding and Eating Disorders/drug therapy ; Feeding and Eating Disorders/physiopathology ; Humans ; Models, Neurological ; Mood Disorders/drug therapy ; Mood Disorders/physiopathology ; Opioid Peptides/agonists ; Opioid Peptides/antagonists & inhibitors ; Reward ; Stress, Physiological/drug effects ; Substance-Related Disorders/drug therapy ; Substance-Related Disorders/physiopathology ; Nociceptin Receptor ; Nociceptin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 20789

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