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Wyszukujesz frazę ""Receptors, G-Protein-Coupled"" wg kryterium: Wszystkie pola


Tytuł:
Mesenchymal Transglutaminase 2 Activates Epithelial ADAM17: Link to G-Protein-Coupled Receptor 56 (ADGRG1) Signalling.
Autorzy:
Bauer L; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Edwards J; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Heil A; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Dewitt S; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Biebermann H; Institute of Experimental Pediatric Endocrinology, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Aeschlimann D; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
Knäuper V; College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff CF14 4XY, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 16; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Glutamine gamma Glutamyltransferase 2*/metabolism
Receptors, G-Protein-Coupled*/genetics
Receptors, G-Protein-Coupled*/metabolism
Humans ; ADAM17 Protein/genetics ; ADAM17 Protein/metabolism ; ErbB Receptors/metabolism ; Ligands ; Signal Transduction
Czasopismo naukowe
Tytuł:
New insight into prurigo nodularis: Proadrenomedullin N-terminal 20 peptide mediates mouse mast cell activation via Mrgprb2.
Autorzy:
Shao Y; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Xiao Z; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Jin Y; Department of Nursing, Huashan Hospital, Fudan University, Shanghai, China.
Zhu Y; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Shen Y; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Jin T; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Tang H; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Wang D; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
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Źródło:
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) [Skin Res Technol] 2024 Feb; Vol. 30 (2), pp. e13588.
Typ publikacji:
Journal Article
MeSH Terms:
Dermatitis, Atopic*/pathology
Prurigo*/metabolism
Prurigo*/pathology
Receptors, G-Protein-Coupled*/genetics
Receptors, G-Protein-Coupled*/metabolism
Animals ; Humans ; Mice ; Adrenomedullin/metabolism ; Immunoglobulin E/metabolism ; Mast Cells/metabolism ; Mast Cells/pathology ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Pruritus ; Receptors, Neuropeptide/genetics ; Receptors, Neuropeptide/metabolism ; Skin/metabolism
Czasopismo naukowe
Tytuł:
The proton-sensing receptors TDAG8 and GPR4 are differentially expressed in human and mouse oligodendrocytes: Exploring their role in neuroinflammation and multiple sclerosis.
Autorzy:
Caratis F; Brain Diseases Centre, Medical University of Gdansk, Gdansk, Poland.; Department of Anatomy and Neurobiology, Medical University of Gdansk, Gdansk, Poland.
Opiełka M; Brain Diseases Centre, Medical University of Gdansk, Gdansk, Poland.
Hausmann M; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Velasco-Estevez M; H12O-CNIO Hematological Malignancies Group, Clinical Research Unit, Centro Nacional de Investigaciones Oncologicas (CNIO), Madrid, Spain.
Rojek B; Department of Adult Neurology, Medical University of Gdansk & University Clinical Centre, Gdansk, Poland.
de Vallière C; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Seuwen K; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Rogler G; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Karaszewski B; Brain Diseases Centre, Medical University of Gdansk, Gdansk, Poland.; Department of Adult Neurology, Medical University of Gdansk & University Clinical Centre, Gdansk, Poland.
Rutkowska A; Brain Diseases Centre, Medical University of Gdansk, Gdansk, Poland.; Department of Anatomy and Neurobiology, Medical University of Gdansk, Gdansk, Poland.
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Źródło:
PloS one [PLoS One] 2024 Mar 25; Vol. 19 (3), pp. e0283060. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Multiple Sclerosis*/genetics
Receptors, G-Protein-Coupled*/metabolism
Oligodendroglia*/metabolism
Animals ; Humans ; Mice ; Genome-Wide Association Study ; Hydrogen-Ion Concentration ; Neuroinflammatory Diseases ; Protons
Czasopismo naukowe
Tytuł:
Bitter Taste Receptor T2R14 and Autophagy Flux in Gingival Epithelial Cells.
Autorzy:
Singh N; Manitoba Chemosensory Biology (MCSB) Research Group, Department of Oral Biology, University of Manitoba, 780 Bannatyne Avenue, Winnipeg, MB R3E 0W4, Canada.; Rady Faculty of Health Sciences, Dr. Gerald Niznick College of Dentistry, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Ulmer B; Manitoba Chemosensory Biology (MCSB) Research Group, Department of Oral Biology, University of Manitoba, 780 Bannatyne Avenue, Winnipeg, MB R3E 0W4, Canada.; Rady Faculty of Health Sciences, Dr. Gerald Niznick College of Dentistry, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Medapati MR; Manitoba Chemosensory Biology (MCSB) Research Group, Department of Oral Biology, University of Manitoba, 780 Bannatyne Avenue, Winnipeg, MB R3E 0W4, Canada.; Rady Faculty of Health Sciences, Dr. Gerald Niznick College of Dentistry, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Zhang C; University of Manitoba Flow Cytometry Core Facility, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Schroth RJ; Manitoba Chemosensory Biology (MCSB) Research Group, Department of Oral Biology, University of Manitoba, 780 Bannatyne Avenue, Winnipeg, MB R3E 0W4, Canada.; Rady Faculty of Health Sciences, Dr. Gerald Niznick College of Dentistry, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.; Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Ghavami S; Research Institute of Oncology and Hematology, Cancer Care Manitoba, University of Manitoba, Winnipeg, MB R3E 0V9, Canada.; Department of Human Anatomy and Cell Science, University of Manitoba College of Medicine, Winnipeg, MB R3E 0W2, Canada.
Chelikani P; Manitoba Chemosensory Biology (MCSB) Research Group, Department of Oral Biology, University of Manitoba, 780 Bannatyne Avenue, Winnipeg, MB R3E 0W4, Canada.; Rady Faculty of Health Sciences, Dr. Gerald Niznick College of Dentistry, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.; Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.; Department of Human Anatomy and Cell Science, University of Manitoba College of Medicine, Winnipeg, MB R3E 0W2, Canada.
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Źródło:
Cells [Cells] 2024 Mar 17; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 17.
Typ publikacji:
Journal Article
MeSH Terms:
Taste*/physiology
Receptors, G-Protein-Coupled*/metabolism
Staphylococcus aureus ; Autophagy ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
G Protein-Coupled Receptor Dimerization-What Next?
Autorzy:
Dziedzicka-Wasylewska M; Department of Pharmacology, Maj Institute of Pharmacology, Polish Academy of Science, Smętna Street 12, 31-343 Kraków, Poland.
Polit A; Department of Physical Biochemistry, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Błasiak E; Department of Physical Biochemistry, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Faron-Górecka A; Department of Pharmacology, Maj Institute of Pharmacology, Polish Academy of Science, Smętna Street 12, 31-343 Kraków, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 07; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Receptors, G-Protein-Coupled*/metabolism
Signal Transduction*
Animals ; Dimerization ; Cell Membrane/metabolism ; Lipids
Czasopismo naukowe
Tytuł:
Platelet-Activating Factor Receptor (PAFR) Regulates Retinal Progenitor/Stem Cells Profile in Ciliary Epithelium Cells.
Autorzy:
Dalmaso B; Department of Cell and Developmental Biology, Biomedical Sciences Institute, University of Sao Paulo, Sao Paulo 05508-000, Brazil.
Silva-Junior IAD; Department of Immunology, Biomedical Sciences Institute, University of Sao Paulo, Sao Paulo 05508-000, Brazil.
Jancar S; Department of Immunology, Biomedical Sciences Institute, University of Sao Paulo, Sao Paulo 05508-000, Brazil.
Del Debbio CB; Department of Cell and Developmental Biology, Biomedical Sciences Institute, University of Sao Paulo, Sao Paulo 05508-000, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 07; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article
MeSH Terms:
Retina*
Stem Cells*/metabolism
Platelet Membrane Glycoproteins*
Receptors, G-Protein-Coupled*
Animals ; Cell Proliferation ; Epithelium ; Mammals
Czasopismo naukowe
Tytuł:
TAS2R38 haplotypes, COVID-19 infection, and symptomatology: a cross-sectional analysis of data from the Canadian Longitudinal Study on Aging.
Autorzy:
Meng T; School of Human Nutrition, McGill University, 21,111 Lakeshore Rd., Room MS2-035, Saint-Anne-de-Bellevue, QC, H9X 3V9, Canada.
Nielsen DE; School of Human Nutrition, McGill University, 21,111 Lakeshore Rd., Room MS2-035, Saint-Anne-de-Bellevue, QC, H9X 3V9, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 26; Vol. 14 (1), pp. 4673. Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/epidemiology
COVID-19*/genetics
Receptors, G-Protein-Coupled*/genetics
Humans ; Aging/genetics ; Canada/epidemiology ; Cross-Sectional Studies ; Haplotypes ; Longitudinal Studies ; Seroepidemiologic Studies ; Taste/genetics
Czasopismo naukowe
Tytuł:
Progestin and adipoQ receptor 7 (PAQR7) mediate the anti-apoptotic effect of P4 on human granulosa cells and its deficiency reduces ovarian function in female mice.
Autorzy:
Li J; School of Basic Medical science, Nanchang University, Nanchang, Jiangxi, 330031, China.; Key Laboratory of Reproductive Physiology and Pathology of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, 330031, China.
Liu Y; School of Basic Medical science, Nanchang University, Nanchang, Jiangxi, 330031, China.; Key Laboratory of Reproductive Physiology and Pathology of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, 330031, China.
He J; Reproductive Medical Center, Jiangxi Maternal and Child Health Hospital, Affiliated Maternal and Child Health Hospital of Nanchang University, Nanchang, Jiangxi, 330006, China.
Wu Z; School of Basic Medical science, Nanchang University, Nanchang, Jiangxi, 330031, China.; Key Laboratory of Reproductive Physiology and Pathology of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, 330031, China.
Wang F; Key Laboratory of Reproductive Physiology and Pathology of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, 330031, China.; Institute of Life Science and School of Life Science, Nanchang University, Nanchang, Jiangxi, 330031, China.
Huang J; School of Basic Medical science, Nanchang University, Nanchang, Jiangxi, 330031, China.; Key Laboratory of Reproductive Physiology and Pathology of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, 330031, China.
Zheng L; Key Laboratory of Reproductive Physiology and Pathology of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, 330031, China. .; School of Public Health, Nanchang University, Nanchang, Jiangxi, 330006, China. .; Jiangxi Provincial Key Laboratory of Preventive Medicine, Nanchang University, Nanchang, 330006, P.R. China. .
Luo T; School of Basic Medical science, Nanchang University, Nanchang, Jiangxi, 330031, China. .; Key Laboratory of Reproductive Physiology and Pathology of Jiangxi Province, Nanchang University, Nanchang, Jiangxi, 330031, China. .; Institute of Life Science and School of Life Science, Nanchang University, Nanchang, Jiangxi, 330031, China. .
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Źródło:
Journal of ovarian research [J Ovarian Res] 2024 Feb 06; Vol. 17 (1), pp. 35. Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Progesterone*/metabolism
Receptors, Progesterone*/metabolism
Receptors, G-Protein-Coupled*/metabolism
Animals ; Female ; Humans ; Mice ; Apoptosis ; Granulosa Cells/metabolism ; Ovarian Follicle/metabolism ; Ovary/metabolism
Czasopismo naukowe
Tytuł:
Information Transmission in G Protein-Coupled Receptors.
Autorzy:
Jones RD; European Centre for Living Technology, University of Venice, 30123 Venice, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 28; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Receptors, G-Protein-Coupled*/genetics
Receptors, G-Protein-Coupled*/metabolism
Drug Delivery Systems*
Humans ; Cell Membrane/metabolism
Czasopismo naukowe
Tytuł:
The Expression of Alamandine Receptor MrgD in Clear Cell Renal Cell Carcinoma Is Associated with a Worse Prognosis and Unfavorable Response to Antiangiogenic Therapy.
Autorzy:
Larrinaga G; Department of Nursing, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.; Department of Physiology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.; Biobizkaia Health Research Institute, 48903 Barakaldo, Spain.
Valdivia A; Department of Cellular Biology and Histology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Arrieta-Aguirre I; Department of Nursing, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.
Solano-Iturri JD; Biobizkaia Health Research Institute, 48903 Barakaldo, Spain.; Department of Pathology, Cruces University Hospital, 48903 Barakaldo, Spain.
Ugalde-Olano A; Biobizkaia Health Research Institute, 48903 Barakaldo, Spain.; Department of Pathology, Basurto University Hospital, 48903 Barakaldo, Spain.
Loizaga-Iriarte A; Biobizkaia Health Research Institute, 48903 Barakaldo, Spain.; Department of Urology, Basurto University Hospital, University of the Basque Country (UPV/EHU), 48013 Bilbao, Spain.
Santos-Martín A; Biobizkaia Health Research Institute, 48903 Barakaldo, Spain.; Department of Urology, Basurto University Hospital, University of the Basque Country (UPV/EHU), 48013 Bilbao, Spain.
Pérez-Fernández A; Biobizkaia Health Research Institute, 48903 Barakaldo, Spain.; Department of Urology, Basurto University Hospital, University of the Basque Country (UPV/EHU), 48013 Bilbao, Spain.
Angulo JC; Clinical Department, Faculty of Medical Sciences, European University of Madrid, 28905 Getafe, Spain.; Department of Urology, University Hospital of Getafe, 28907 Madrid, Spain.
López JI; Biobizkaia Health Research Institute, 48903 Barakaldo, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 25; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Renal Cell*/drug therapy
Carcinoma, Renal Cell*/genetics
Carcinoma, Renal Cell*/metabolism
Kidney Neoplasms*/drug therapy
Kidney Neoplasms*/genetics
Kidney Neoplasms*/metabolism
Receptors, G-Protein-Coupled*/genetics
Receptors, G-Protein-Coupled*/metabolism
Humans ; Carrier Proteins ; Kidney/metabolism ; Oligopeptides/metabolism ; Oligopeptides/pharmacology
Czasopismo naukowe
Tytuł:
Anti-Inflammatory Effect of Synaptamide in Ischemic Acute Kidney Injury and the Role of G-Protein-Coupled Receptor 110.
Autorzy:
Brezgunova AA; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119992 Moscow, Russia.
Andrianova NV; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Saidova AA; Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Potashnikova DM; Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Abramicheva PA; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Manskikh VN; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Mariasina SS; Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.; Faculty of Fundamental Medicine, Lomonosov Moscow State University, 119991 Moscow, Russia.; Research and Educational Resource Center 'Pharmacy', RUDN University, 117198 Moscow, Russia.
Pevzner IB; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of Russian Federation, 117198 Moscow, Russia.
Zorova LD; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of Russian Federation, 117198 Moscow, Russia.
Manzhulo IV; A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, Russia.
Zorov DB; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of Russian Federation, 117198 Moscow, Russia.
Plotnikov EY; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of Russian Federation, 117198 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 25; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Kidney Injury*/drug therapy
Acute Kidney Injury*/metabolism
Ethanolamines*
Receptors, G-Protein-Coupled*/drug effects
Receptors, G-Protein-Coupled*/metabolism
Reperfusion Injury*/drug therapy
Reperfusion Injury*/metabolism
Animals ; Rats ; Anti-Inflammatory Agents/metabolism ; Interleukins/metabolism ; Kidney/metabolism
Czasopismo naukowe
Tytuł:
A tool kit of highly selective and sensitive genetically encoded neuropeptide sensors.
Autorzy:
Wang H; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Qian T; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Zhao Y; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Zhuo Y; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Wu C; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Osakada T; Department of Psychiatry and Department of Neuroscience and Physiology, New York University Langone Medical Center, New York, NY 10016, USA.
Chen P; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.; Chinese Academy of Sciences Key Laboratory of Brain Function and Diseases, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Chen Z; Shenzhen Key Laboratory of Drug Addiction, Shenzhen Neher Neural Plasticity Laboratory, Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Ren H; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Yan Y; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Geng L; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Fu S; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Mei L; Department of Psychiatry and Department of Neuroscience and Physiology, New York University Langone Medical Center, New York, NY 10016, USA.
Li G; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Wu L; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Jiang Y; Department of Psychiatry and Department of Neuroscience and Physiology, New York University Langone Medical Center, New York, NY 10016, USA.
Qian W; Institute of Molecular Medicine, Peking University, Beijing 100871, China.
Zhang L; Department of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Peng W; Chinese Academy of Sciences Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Xu M; Chinese Academy of Sciences Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Hu J; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Jiang M; Department of Physiology, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Chen L; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Tang C; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.
Zhu Y; Shenzhen Key Laboratory of Drug Addiction, Shenzhen Neher Neural Plasticity Laboratory, Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Lin D; Department of Psychiatry and Department of Neuroscience and Physiology, New York University Langone Medical Center, New York, NY 10016, USA.
Zhou JN; Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.; Chinese Academy of Sciences Key Laboratory of Brain Function and Diseases, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China.
Li Y; State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Beijing 100871, China.; IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.; National Biomedical Imaging Center, Peking University, Beijing 100871, China.
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Źródło:
Science (New York, N.Y.) [Science] 2023 Nov 17; Vol. 382 (6672), pp. eabq8173. Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Biosensing Techniques*
Neuropeptides*/analysis
Neuropeptides*/metabolism
Receptors, G-Protein-Coupled*/agonists
Receptors, G-Protein-Coupled*/genetics
Neurons*/chemistry
Islets of Langerhans*/chemistry
Humans ; Fluorescence ; HEK293 Cells ; Cerebral Cortex/chemistry ; Animals ; Rats
Czasopismo naukowe
Tytuł:
Investigating the role of the relaxin-3/RXFP3 system in neuropsychiatric disorders and metabolic phenotypes: A candidate gene approach.
Autorzy:
Wong WLE; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Arathimos R; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom.
Lewis CM; Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, United Kingdom.; Faculty of Life Sciences and Medicine, Department of Medical and Molecular Genetics, King's College London, London, United Kingdom.
Young AH; Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.; South London & Maudsley NHS Foundation Trust, Bethlem Royal Hospital, London, United Kingdom.
Dawe GS; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Life Sciences Institute, Neurobiology Programme, National University of Singapore, Singapore, Singapore.
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Źródło:
PloS one [PLoS One] 2023 Nov 15; Vol. 18 (11), pp. e0294045. Date of Electronic Publication: 2023 Nov 15 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, G-Protein-Coupled*/genetics
Receptors, G-Protein-Coupled*/metabolism
Relaxin*/genetics
Relaxin*/metabolism
Animals ; Humans ; Phenotype ; Retrospective Studies ; Signal Transduction
Czasopismo naukowe
Tytuł:
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors.
Autorzy:
Maharana J; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
Sano FK; Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Sarma P; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
Yadav MK; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
Duan L; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Stepniewski TM; Research Program on Biomedical Informatics, Hospital del Mar Research Institute and Pompeu Fabra University, Barcelona, Spain.
Chaturvedi M; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
Ranjan A; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
Singh V; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
Saha S; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
Mahajan G; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
Chami M; BioEM Lab, Biozentrum, University of Basel, Basel, Switzerland.
Shihoya W; Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Selent J; Research Program on Biomedical Informatics, Hospital del Mar Research Institute and Pompeu Fabra University, Barcelona, Spain.
Chung KY; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Banerjee R; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
Nureki O; Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Shukla AK; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Jan 05; Vol. 383 (6678), pp. 101-108. Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
beta-Arrestins*/chemistry
Receptors, G-Protein-Coupled*/chemistry
Protein Interaction Domains and Motifs*
Cryoelectron Microscopy ; Signal Transduction ; Protein Conformation, beta-Strand ; Protein Conformation, alpha-Helical ; Humans
Czasopismo naukowe
Tytuł:
Mechanistic Insights into Peptide Binding and Deactivation of an Adhesion G Protein-Coupled Receptor.
Autorzy:
Adediwura VA; Department of Pharmacology and Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Miao Y; Department of Pharmacology and Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 27; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 27.
Typ publikacji:
Journal Article
MeSH Terms:
Molecular Dynamics Simulation*
Receptors, G-Protein-Coupled*/genetics
Male ; Humans ; Physical Phenomena ; Cell Proliferation ; Mutation
Czasopismo naukowe
Tytuł:
Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors.
Autorzy:
Nakajima S; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.
Demers G; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.; Department of Nutrition, Université de Montréal, Montréal, QC, H3T1J4, Canada.
Machuca-Parra AI; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.
Pour ZD; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.; Department of Nutrition, Université de Montréal, Montréal, QC, H3T1J4, Canada.
Bairamian D; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.; Department of Nutrition, Université de Montréal, Montréal, QC, H3T1J4, Canada.
Bouyakdan K; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.
Fisette A; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.; Research Group in Cellular Signaling, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, Canada.
Kabahizi A; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.; Department of Nutrition, Université de Montréal, Montréal, QC, H3T1J4, Canada.
Robb J; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.
Rodaros D; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.
Laurent C; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.; Department of Neuroscience, Université de Montréal, Montréal, QC, H3T1J4, Canada.
Ferreira G; Nutrition and Integrative Neurobiology Unit, UMR 1286, INRA-Université de Bordeaux, Bordeaux, France.
Arbour N; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.; Department of Neuroscience, Université de Montréal, Montréal, QC, H3T1J4, Canada.
Alquier T; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada.; Department of Medicine, Université de Montréal, Montréal, QC, H3T1J4, Canada.
Fulton S; Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, H3T1J4, Canada. .; Department of Nutrition, Université de Montréal, Montréal, QC, H3T1J4, Canada. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2023 Dec 19; Vol. 20 (1), pp. 302. Date of Electronic Publication: 2023 Dec 19.
Typ publikacji:
Journal Article
MeSH Terms:
Fatty Acids, Omega-3*/pharmacology
Microglia*/metabolism
Receptors, G-Protein-Coupled*/metabolism
Adult ; Animals ; Humans ; Mice ; Anxiety/chemically induced ; Anxiety/drug therapy ; Fatty Acids/metabolism ; Inflammation/metabolism ; Lipopolysaccharides/toxicity ; Neuroinflammatory Diseases ; RNA, Messenger/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
GPRC5C regulates the composition of cilia in the olfactory system.
Autorzy:
Bhat S; Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Drackendorfer Str. 1, 07747, Jena, Germany.
Dietz A; Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Drackendorfer Str. 1, 07747, Jena, Germany.
Senf K; Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Drackendorfer Str. 1, 07747, Jena, Germany.
Nietzsche S; Centre for Electron Microscopy, Jena University Hospital, Friedrich Schiller University Jena, Ziegelmühlenweg 1, 07743, Jena, Germany.
Hirabayashi Y; Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Chiba, 279-0021, Japan.; RIKEN Cluster for Pioneering Research, RIKEN, Wako, Saitama, 351-0198, Japan.
Westermann M; Centre for Electron Microscopy, Jena University Hospital, Friedrich Schiller University Jena, Ziegelmühlenweg 1, 07743, Jena, Germany.
Neuhaus EM; Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Drackendorfer Str. 1, 07747, Jena, Germany. .
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Źródło:
BMC biology [BMC Biol] 2023 Dec 18; Vol. 21 (1), pp. 292. Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cilia*/metabolism
Olfactory Receptor Neurons*/physiology
Receptors, G-Protein-Coupled*/metabolism
Animals ; Mice ; Mice, Knockout ; Odorants ; Smell/physiology
Czasopismo naukowe
Tytuł:
Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174.
Autorzy:
Liu G; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.
Li X; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.
Wang Y; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.
Zhang X; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Gong W; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.
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Źródło:
PLoS biology [PLoS Biol] 2023 Dec 04; Vol. 21 (12), pp. e3002387. Date of Electronic Publication: 2023 Dec 04 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Lysophospholipids*/pharmacology
Lysophospholipids*/metabolism
Receptors, G-Protein-Coupled*/metabolism
Humans ; Ligands ; Receptors, Lysophospholipid/agonists ; Receptors, Lysophospholipid/metabolism
Czasopismo naukowe
Tytuł:
PROKR2 Mutations in Patients with Short Stature Who Have Isolated Growth Hormone Deficiency and Multiple Pituitary Hormone Deficiency
Autorzy:
Kardelen AD; İstanbul University, İstanbul Faculty of Medicine, Department of Pediatric Endocrinology, İstanbul, Turkey
Najafli A; İstanbul University, İstanbul Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey
Baş F; İstanbul University, İstanbul Faculty of Medicine, Department of Pediatric Endocrinology, İstanbul, Turkey
Karaman B; İstanbul University, İstanbul Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey; İstanbul University, Institute of Child Health, Department of Pediatric Basic Sciences, İstanbul, Turkey
Toksoy G; İstanbul University, İstanbul Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey
Poyrazoğlu Ş; İstanbul University, İstanbul Faculty of Medicine, Department of Pediatric Endocrinology, İstanbul, Turkey
Avcı Ş; İstanbul University, İstanbul Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey; Koç University Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey
Altunoğlu U; İstanbul University, İstanbul Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey; Marmara University Faculty of Medicine, Department of Pediatric Endocrinology, İstanbul, Turkey
Yavaş Abalı Z; İstanbul University, İstanbul Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey; Marmara University Faculty of Medicine, Department of Pediatric Endocrinology, İstanbul, Turkey
Öztürk AP; İstanbul University, İstanbul Faculty of Medicine, Department of Pediatric Endocrinology, İstanbul, Turkey
Karakılıç Özturan E; İstanbul University, İstanbul Faculty of Medicine, Department of Pediatric Endocrinology, İstanbul, Turkey
Başaran S; İstanbul University, İstanbul Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey
Darendeliler F; İstanbul University, İstanbul Faculty of Medicine, Department of Pediatric Endocrinology, İstanbul, Turkey
Uyguner ZO; İstanbul University, İstanbul Faculty of Medicine, Department of Medical Genetics, İstanbul, Turkey
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Źródło:
Journal of clinical research in pediatric endocrinology [J Clin Res Pediatr Endocrinol] 2023 Nov 22; Vol. 15 (4), pp. 338-347. Date of Electronic Publication: 2023 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
Growth Hormone*/genetics
Pituitary Hormones*/genetics
Dwarfism, Pituitary*/genetics
Receptors, G-Protein-Coupled*/genetics
Humans ; Pedigree ; Male ; Female ; Infant ; Child ; Consanguinity
Czasopismo naukowe
Tytuł:
The Posttraumatic Increase in the Adhesion of GPCR EMR2/ ADGRE2 to Circulating Neutrophils Is Not Related to Injury Severity.
Autorzy:
Zheng L; Research Laboratories and Department of Orthopaedics, Trauma and Plastic Surgery (OUP), Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.
Rang M; Research Laboratories and Department of Orthopaedics, Trauma and Plastic Surgery (OUP), Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.
Fuchs C; Research Laboratories and Department of Orthopaedics, Trauma and Plastic Surgery (OUP), Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.
Keß A; Research Laboratories and Department of Orthopaedics, Trauma and Plastic Surgery (OUP), Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.
Wunsch M; Research Laboratories and Department of Orthopaedics, Trauma and Plastic Surgery (OUP), Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.
Hentschel J; Institute of Human Genetics, Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.
Hsiao CC; Department of Experimental Immunology, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
Kleber C; Research Laboratories and Department of Orthopaedics, Trauma and Plastic Surgery (OUP), Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.
Osterhoff G; Research Laboratories and Department of Orthopaedics, Trauma and Plastic Surgery (OUP), Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.
Aust G; Research Laboratories and Department of Orthopaedics, Trauma and Plastic Surgery (OUP), Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.; Research Laboratories and Department of Visceral, Transplantation, Vascular and Thoracic Surgery (VTTG), Leipzig University and University Hospital Leipzig, 04103 Leipzig, Germany.
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Źródło:
Cells [Cells] 2023 Nov 20; Vol. 12 (22). Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neutrophils*/metabolism
Receptors, G-Protein-Coupled*/metabolism
Wounds and Injuries*
Humans ; Cytokines/metabolism
Czasopismo naukowe

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