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Wyświetlanie 1-20 z 1706
Tytuł:
Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the machine learning method framework cTAP.
Autorzy:
Wang H; Computer Science and Engineering Department, University of Connecticut, Storrs, USA. .
Joshi P; Computer Science and Engineering Department, University of Connecticut, Storrs, USA.
Hong SH; Computer Science and Engineering Department, University of Connecticut, Storrs, USA.
Maye PF; Department of Reconstructive Sciences, University of Connecticut Health Center, Farmington, USA.
Rowe DW; Center for Regenerative Medicine and Skeletal Development, University of Connecticut Health Center, Farmington, USA.
Shin DG; Computer Science and Engineering Department, University of Connecticut, Storrs, USA. .
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Źródło:
BMC genomics [BMC Genomics] 2022 Jan 07; Vol. 23 (1), pp. 14. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
Osteoclasts*/metabolism
RANK Ligand*/metabolism
Cell Differentiation ; Humans ; Interferon Regulatory Factors/genetics ; Interferon Regulatory Factors/metabolism ; Machine Learning ; NFATC Transcription Factors/genetics ; NFATC Transcription Factors/metabolism ; T-Lymphocytes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transplanting cells from old but not young donors causes physical dysfunction in older recipients.
Autorzy:
Wang B; UConn Center on Aging, UConn Health, Farmington, Connecticut.; Department of Genetics and Genome Sciences, UConn Health, Farmington, Connecticut.
Liu Z; UConn Center on Aging, UConn Health, Farmington, Connecticut.; Department of Genetics and Genome Sciences, UConn Health, Farmington, Connecticut.; Biomedical Science Graduate Program, UConn Health, Farmington, Connecticut.
Chen VP; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota.
Wang L; UConn Center on Aging, UConn Health, Farmington, Connecticut.; Department of Genetics and Genome Sciences, UConn Health, Farmington, Connecticut.
Inman CL; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota.
Zhou Y; Xiangya Stomatological Hospital, Central South University, Changsha, China.; Center for Regenerative Medicine and Skeletal Development, UConn Health, UConn Health, Farmington, Connecticut.
Guo C; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota.; Center for Regenerative Medicine and Skeletal Development, UConn Health, UConn Health, Farmington, Connecticut.
Tchkonia T; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota.
Rowe DW; Center for Regenerative Medicine and Skeletal Development, UConn Health, UConn Health, Farmington, Connecticut.
Kuchel GA; UConn Center on Aging, UConn Health, Farmington, Connecticut.
Robson P; Department of Genetics and Genome Sciences, UConn Health, Farmington, Connecticut.; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut.
Kirkland JL; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota.
Xu M; UConn Center on Aging, UConn Health, Farmington, Connecticut.; Department of Genetics and Genome Sciences, UConn Health, Farmington, Connecticut.; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota.
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Źródło:
Aging cell [Aging Cell] 2020 Mar; Vol. 19 (3), pp. e13106. Date of Electronic Publication: 2020 Jan 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Tissue Donors*
Transplant Recipients*
Frailty/*etiology
Mesenchymal Stem Cell Transplantation/*adverse effects
Mesenchymal Stem Cell Transplantation/*methods
Age Factors ; Animals ; Biomarkers ; Cellular Senescence/genetics ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Longevity/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Physical Endurance ; Regenerative Medicine/methods ; Single-Cell Analysis/methods ; Transcriptome ; Walking Speed
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity.
Autorzy:
Carriquí-Madroñal, Belén (AUTHOR)
Sheldon, Julie (AUTHOR)
Duven, Mara (AUTHOR)
Stegmann, Cora (AUTHOR)
Cirksena, Karsten (AUTHOR)
Wyler, Emanuel (AUTHOR)
Zapatero-Belinchón, Francisco J. (AUTHOR)
Vondran, Florian W. R. (AUTHOR)
Gerold, Gisa (AUTHOR)
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Źródło:
PLoS Pathogens. 11/15/2023, Vol. 19 Issue 11, p1-24. 24p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Murine supraspinatus tendon injury model to identify the cellular origins of rotator cuff healing.
Autorzy:
Yoshida R; a Department of Orthopaedic Surgery , University of Connecticut Health Center , Farmington , CT , USA.
Alaee F; a Department of Orthopaedic Surgery , University of Connecticut Health Center , Farmington , CT , USA.
Dyrna F; a Department of Orthopaedic Surgery , University of Connecticut Health Center , Farmington , CT , USA.
Kronenberg MS; b Department of Reconstructive Sciences , University of Connecticut Health Center , Farmington , CT , USA.
Maye P; b Department of Reconstructive Sciences , University of Connecticut Health Center , Farmington , CT , USA.
Kalajzic I; b Department of Reconstructive Sciences , University of Connecticut Health Center , Farmington , CT , USA.
Rowe DW; b Department of Reconstructive Sciences , University of Connecticut Health Center , Farmington , CT , USA.
Mazzocca AD; a Department of Orthopaedic Surgery , University of Connecticut Health Center , Farmington , CT , USA.
Dyment NA; b Department of Reconstructive Sciences , University of Connecticut Health Center , Farmington , CT , USA.
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Źródło:
Connective tissue research [Connect Tissue Res] 2016 Nov; Vol. 57 (6), pp. 507-515. Date of Electronic Publication: 2016 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
Wound Healing*
Rotator Cuff/*pathology
Rotator Cuff Injuries/*pathology
Animals ; Deltoid Muscle/pathology ; Disease Models, Animal ; Genes, Reporter ; Integrases/metabolism ; Mice, Transgenic ; Shoulder Dislocation/pathology ; Shoulder Injuries ; Shoulder Joint/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetics of aging bone.
Autorzy:
Adams DJ; Department of Orthopaedic Surgery, University of Connecticut Musculoskeletal Institute, University of Connecticut Health, Farmington, CT, 06030, USA.
Rowe DW; Center for Regenerative Medicine and Skeletal Development, Department of Reconstructive Sciences, Biomaterials and Skeletal Development, University of Connecticut Health, Farmington, CT, USA.
Ackert-Bicknell CL; Center for Musculoskeletal Research, Department of Orthopaedics and Rehabilitation, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Ave, Box 665, Rochester, NY, 14624, USA. cheryl_.
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Źródło:
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2016 Aug; Vol. 27 (7-8), pp. 367-80. Date of Electronic Publication: 2016 Jun 06.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
Fractures, Bone/*genetics
Osteoporosis/*genetics
Skeleton/*physiopathology
Aging/genetics ; Aging/pathology ; Bone Density ; Chromosome Mapping ; Fractures, Bone/physiopathology ; Humans ; Osteoporosis/physiopathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 1706

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