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Tytuł:
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer: Gudmundsson J, Sulem P, Rafnar T, Bergthorsson JT, Manolescu A, Gudbjartsson D, Agnarsson BA, Sigurdsson A, Benediktsdottir KR, Blondal T, Jakobsdottir M, Stacey SN, Kostic J, Kristinsson KT, Birgisdottir B, Ghosh S, Magnusdottir DN, Thorlacius S, Thorleifsson G, Zheng SL, Sun J, Chang BL, Elmore JB, Breyer JP, McReynolds KM, Bradley KM, Yaspan BL, Wiklund F, Stattin P, Lindström S, Adami HO, McDonnell SK, Schaid DJ, Cunningham JM, Wang L, Cerhan JR, St Sauver JL, Isaacs SD, Wiley KE, Partin AW, Walsh PC, Polo S, Ruiz-Echarri M, Navarrete S, Fuertes F, Saez B, Godino J, Weijerman PC, Swinkels DW, Aben KK, Witjes JA, Suarez BK, Helfand BT, Frigge ML, Kristjansson K, Ober C, Jonsson E, Einarsson GV, Xu J, Gronberg H, Smith JR, Thibodeau SN, Isaacs WB, Catalona WJ, Mayordomo JI, Kiemeney LA, Barkardottir RB, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K, deCODE Genetics, 101 Reykjavik, Iceland
Autorzy:
Brooks, James
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Źródło:
In Urologic Oncology: Seminars and Original Investigations 2008 26(5):569-570
Czasopismo naukowe
Tytuł:
Genetic Predictors of Chemotherapy-Induced Peripheral Neuropathy from Paclitaxel, Carboplatin and Oxaliplatin: NCCTG/Alliance N08C1, N08CA and N08CB Study.
Autorzy:
Adjei AA; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.; Alliance Cancer Control Program, Mayo Clinic, Rochester, MN 55905, USA.
Lopez CL; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Schaid DJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Sloan JA; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.; Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN 55905, USA.
Le-Rademacher JG; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.; Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN 55905, USA.
Loprinzi CL; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.; Alliance Cancer Control Program, Mayo Clinic, Rochester, MN 55905, USA.; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Norman AD; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Olson JE; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Beutler AS; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Vachon CM; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Ruddy KJ; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.; Alliance Cancer Control Program, Mayo Clinic, Rochester, MN 55905, USA.
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Źródło:
Cancers [Cancers (Basel)] 2021 Mar 03; Vol. 13 (5). Date of Electronic Publication: 2021 Mar 03.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Genetic Variations and Health-Related Quality of Life (HRQOL): A Genome-Wide Study Approach.
Autorzy:
Adjei AA; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Lopez CL; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
Schaid DJ; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
Sloan JA; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
Le-Rademacher JG; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
Loprinzi CL; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Norman AD; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
Couch FJ; Department of Laboratory Medicine and Pathology, Rochester, MN 55905, USA.
Beutler AS; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Vachon CM; Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.
Ruddy KJ; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
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Źródło:
Cancers [Cancers (Basel)] 2021 Feb 10; Vol. 13 (4). Date of Electronic Publication: 2021 Feb 10.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Do Hispanic Puerto Rican men have worse outcomes after radical prostatectomy? Results from SEARCH.
Autorzy:
Guerrios‐Rivera, Lourdes (AUTHOR)
Janes, Jessica L. (AUTHOR)
De Hoedt, Amanda M. (AUTHOR)
Klaassen, Zachary (AUTHOR)
Terris, Martha K. (AUTHOR)
Cooperberg, Matthew R. (AUTHOR)
Amling, Christopher L. (AUTHOR)
Kane, Christopher J. (AUTHOR)
Aronson, William J. (AUTHOR)
Fowke, Jay H. (AUTHOR)
Freedland, Stephen J. (AUTHOR)
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Źródło:
Cancer Medicine. Feb2024, Vol. 13 Issue 4, p1-9. 9p.
Czasopismo naukowe
Tytuł:
Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study.
Autorzy:
Hu Y; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Graff M; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Haessler J; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Buyske S; Department of Statistics and Biostatistics, Rutgers University, New Brunswick, New Jersey, United States of America.
Bien SA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Tao R; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; The Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Highland HM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Nishimura KK; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Zubair N; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Lu Y; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Verbanck M; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Hilliard AT; Palo Alto Veterans Institute for Research, VA Palo Alto Health Care System, Palo Alto, California, United States of America.
Klarin D; Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Boston VA Healthcare System, Boston, Massachusetts, United States of America.
Damrauer SM; Emory Clinical Cardiovascular Research Institute, Atlanta, Georgia, United States of America.; Corporal Michael Crescenz VA Medical Center, Philadelphia, Pennsylvania, United States of America.; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Ho YL; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, United States of America.
Wilson PWF; Emory Clinical Cardiovascular Research Institute, Atlanta, Georgia, United States of America.; Atlanta VA Medical Center, Decatur, Georgia, United States of America.
Chang KM; Corporal Michael Crescenz VA Medical Center, Philadelphia, Pennsylvania, United States of America.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Tsao PS; Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.; VA Palo Alto Health Care System, Palo Alto, California, United States of America.
Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, United States of America.
O'Donnell CJ; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, United States of America.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.
Assimes TL; Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.; VA Palo Alto Health Care System, Palo Alto, California, United States of America.
Petty LE; The Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Department of Epidemiology, Human Genetics & Environmental Sciences, University of Texas School of Public Health, Houston, Texas, United States of America.
Below JE; The Vanderbilt Genetics Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.; Department of Epidemiology, Human Genetics & Environmental Sciences, University of Texas School of Public Health, Houston, Texas, United States of America.
Dikilitas O; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Schaid DJ; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
Kosel ML; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
Kullo IJ; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
Jarvik GP; Department of Medicine, University of Washington Medical Center, Seattle, Washington, United States of America.
Feng Q; Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Wei WQ; Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Larson EB; Kaiser Permanente Washington Health Research Institute, Seattle, Washington, United States of America.
Mentch FD; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.
Almoguera B; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.
Sleiman PM; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.
Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Correa A; Departments of Medicine, Pediatrics, and Population Health Science, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.
Martin LW; School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia, United States of America.
Daviglus M; Institute for Minority Health Research, University of Illinois at Chicago, Chicago, Illinois, United States of America.; Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, United States of America.
Matise TC; Department of Statistics and Biostatistics, Rutgers University, New Brunswick, New Jersey, United States of America.
Ambite JL; Information Sciences Institute, University of Southern California, Marina del Rey, California, United States of America.
Carlson CS; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Do R; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Loos RJF; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Wilkens LR; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, United States of America.
Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, United States of America.
Haiman C; Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Stram DO; Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Hindorff LA; Division of Genomic Medicine, NIH National Human Genome Research Institute, Bethesda, Maryland, United States of America.
North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Kooperberg C; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Cheng I; Cancer Prevention Institute of California, Fremont, California, United States of America.
Peters U; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
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Corporate Authors:
VA Million Veteran Program
Źródło:
PLoS genetics [PLoS Genet] 2020 Mar 30; Vol. 16 (3), pp. e1008684. Date of Electronic Publication: 2020 Mar 30 (Print Publication: 2020).
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Lipids/*blood
Lipids/*genetics
Racial Groups/*genetics
Databases, Genetic ; Female ; Genome-Wide Association Study/methods ; Genotype ; Humans ; Lipids/analysis ; Male ; Metagenomics/methods ; Minority Groups ; Multifactorial Inheritance/genetics ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; United States/epidemiology
Czasopismo naukowe
Tytuł:
Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics.
Autorzy:
Yazdani A; Boston University, Boston, MA, 02118, USA. .
Yazdani A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, 10029, USA.
Elsea SH; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
Schaid DJ; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA.
Kosorok MR; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Dangol G; Health Science Center, The University of Texas MD Anderson Cancer Center, Austin, TX, 77030, USA.
Samiei A; Hasso Plattner Institute, 14482, Potsdam, Germany.; Climax Data Pattern, Boston, MA, USA.
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Źródło:
BMC genomics [BMC Genomics] 2019 May 21; Vol. 20 (1), pp. 395. Date of Electronic Publication: 2019 May 21.
Typ publikacji:
Journal Article
MeSH Terms:
Genetic Pleiotropy*
Genome, Human*
Metabolomics*
Mutation*
Metabolome/*genetics
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Black or African American/genetics ; Algorithms ; Humans ; White People/genetics
Czasopismo naukowe
Tytuł:
An expanded variant list and assembly annotation identifies multiple novel coding and noncoding genes for prostate cancer risk using a normal prostate tissue eQTL data set.
Autorzy:
DeRycke MS; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Larson MC; Department of Health Sciences Research, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Nair AA; Department of Health Sciences Research, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
McDonnell SK; Department of Health Sciences Research, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
French AJ; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Tillmans LS; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Riska SM; Department of Health Sciences Research, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Baheti S; Department of Health Sciences Research, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Fogarty ZC; Department of Health Sciences Research, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Larson NB; Department of Health Sciences Research, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
O'Brien DR; Department of Health Sciences Research, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Cheville JC; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Wang L; Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
Schaid DJ; Department of Health Sciences Research, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
Thibodeau SN; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, SW, Rochester, Minnesota, United States of America.
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Źródło:
PloS one [PLoS One] 2019 Apr 08; Vol. 14 (4), pp. e0214588. Date of Electronic Publication: 2019 Apr 08 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Genetic Predisposition to Disease*
Linkage Disequilibrium*
Quantitative Trait Loci*
Prostatic Neoplasms/*diagnosis
Genetic Variation ; Genome-Wide Association Study ; Genotype ; Humans ; Male ; Polymorphism, Single Nucleotide ; Prostate/pathology ; Prostatic Neoplasms/genetics ; Quality Control ; Risk Factors ; Sequence Analysis, RNA ; Transcriptome
Czasopismo naukowe
Tytuł:
Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China.
Autorzy:
Wu, Shan (AUTHOR)
Wu, Zhidan (AUTHOR)
Chen, Manlian (AUTHOR)
Zhong, Xiangbin (AUTHOR)
Gu, Haoyan (AUTHOR)
Du, Wenjing (AUTHOR)
Liu, Weidong (AUTHOR)
Lang, Li (AUTHOR)
Wang, Junyi (AUTHOR)
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Źródło:
BMC Medical Genomics. 1/11/2024, Vol. 17 Issue 1, p1-12. 12p.
Czasopismo naukowe
Tytuł:
cLD: Rare-variant linkage disequilibrium between genomic regions identifies novel genomic interactions.
Autorzy:
Wang, Dinghao (AUTHOR)
Perera, Deshan (AUTHOR)
He, Jingni (AUTHOR)
Cao, Chen (AUTHOR)
Kossinna, Pathum (AUTHOR)
Li, Qing (AUTHOR)
Zhang, William (AUTHOR)
Guo, Xingyi (AUTHOR)
Platt, Alexander (AUTHOR)
Wu, Jingjing (AUTHOR)
Zhang, Qingrun (AUTHOR)
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Źródło:
PLoS Genetics. 12/18/2023, Vol. 19 Issue 12, p1-21. 21p.
Czasopismo naukowe
Tytuł:
Evaluating 17 methods incorporating biological function with GWAS summary statistics to accelerate discovery demonstrates a tradeoff between high sensitivity and high positive predictive value.
Autorzy:
Moore, Amy (AUTHOR)
Marks, Jesse A. (AUTHOR)
Quach, Bryan C. (AUTHOR)
Guo, Yuelong (AUTHOR)
Bierut, Laura J. (AUTHOR)
Gaddis, Nathan C. (AUTHOR)
Hancock, Dana B. (AUTHOR)
Page, Grier P. (AUTHOR)
Johnson, Eric O. (AUTHOR)
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Źródło:
Communications Biology. 11/23/2023, Vol. 6 Issue 1, p1-14. 14p.
Czasopismo naukowe

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