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Tytuł:
Therapeutic Effects of Mesenchymal Stromal Cells Require Mitochondrial Transfer and Quality Control.
Autorzy:
Mukkala AN; Unity Health Toronto, The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, University of Toronto, Toronto, ON M5B 1T8, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada.
Jerkic M; Unity Health Toronto, The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, University of Toronto, Toronto, ON M5B 1T8, Canada.
Khan Z; Unity Health Toronto, The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, University of Toronto, Toronto, ON M5B 1T8, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada.
Szaszi K; Unity Health Toronto, The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, University of Toronto, Toronto, ON M5B 1T8, Canada.; Department of Surgery, University of Toronto, Toronto, ON M5T 1P5, Canada.
Kapus A; Unity Health Toronto, The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, University of Toronto, Toronto, ON M5B 1T8, Canada.; Department of Surgery, University of Toronto, Toronto, ON M5T 1P5, Canada.
Rotstein O; Unity Health Toronto, The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, University of Toronto, Toronto, ON M5B 1T8, Canada.; Department of Surgery, University of Toronto, Toronto, ON M5T 1P5, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 31; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Nanotubes*
Mesenchymal Stem Cells*/metabolism
Humans ; Mitochondria ; Inflammation/therapy ; Inflammation/metabolism
Czasopismo naukowe
Tytuł:
Key Role of Mesenchymal Stromal Cell Interaction with Macrophages in Promoting Repair of Lung Injury.
Autorzy:
Jerkic M; The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, ON M5B 1T8, Canada.
Szaszi K; The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, ON M5B 1T8, Canada.; Department of Surgery, University of Toronto, Toronto, ON M5T 1P5, Canada.
Laffey JG; The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, ON M5B 1T8, Canada.; Anaesthesia and Intensive Care Medicine, School of Medicine, University of Galway, H91 TK33 Galway, Ireland.
Rotstein O; The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, ON M5B 1T8, Canada.; Department of Surgery, University of Toronto, Toronto, ON M5T 1P5, Canada.
Zhang H; The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, ON M5B 1T8, Canada.; Department of Anesthesiology and Pain Medicine, Interdepartmental Division of Critical Care Medicine and Department of Physiology, University of Toronto, Toronto, ON M5G 1E2, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 08; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lung Injury*
COVID-19*
Mesenchymal Stem Cells*
Humans ; Macrophages ; Macrophages, Alveolar
Czasopismo naukowe
Tytuł:
Tiny Guides, Big Impact: Focus on the Opportunities and Challenges of miR-Based Treatments for ARDS.
Autorzy:
Vaswani, Chirag M. (AUTHOR)
Simone, Julia (AUTHOR)
Pavelick, Jacqueline L. (AUTHOR)
Wu, Xiao (AUTHOR)
Tan, Greaton W. (AUTHOR)
Ektesabi, Amin M. (AUTHOR)
Gupta, Sahil (AUTHOR)
Tsoporis, James N. (AUTHOR)
dos Santos, Claudia C. (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 5, p2812. 21p.
Czasopismo naukowe
Tytuł:
Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κ B activation.
Autorzy:
Ailenberg, M
Di Ciano ‐ Oliveira, C
Szaszi, K
Dan, Q
Rozycki, M
Kapus, A
Rotstein, O D
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Temat:
CELLULAR signal transduction
ENDOCYTOSIS
NF-kappa B
ANTIVIRAL agents
CLATHRIN
Źródło:
British Journal of Pharmacology; Aug2015, Vol. 172 Issue 15, p3748-3763, 16p, 2 Color Photographs, 7 Black and White Photographs, 1 Graph
Czasopismo naukowe
Tytuł:
The Plastic Interplay between Lung Regeneration Phenomena and Fibrotic Evolution: Current Challenges and Novel Therapeutic Perspectives.
Autorzy:
Lettieri, Sara (AUTHOR)
Bertuccio, Francesco R. (AUTHOR)
del Frate, Lucia (AUTHOR)
Perrotta, Fabio (AUTHOR)
Corsico, Angelo G. (AUTHOR)
Stella, Giulia M. (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Jan2024, Vol. 25 Issue 1, p547. 27p.
Czasopismo naukowe
Tytuł:
De-Suppression of Mesenchymal Cell Identities and Variable Phenotypic Outcomes Associated with Knockout of Bbs1.
Autorzy:
Freke, Grace Mercedes (AUTHOR)
Martins, Tiago (AUTHOR)
Davies, Rosalind Jane (AUTHOR)
Beyer, Tina (AUTHOR)
Seda, Marian (AUTHOR)
Peskett, Emma (AUTHOR)
Haq, Naila (AUTHOR)
Prasai, Avishek (AUTHOR)
Otto, Georg (AUTHOR)
Jeyabalan Srikaran, Jeshmi (AUTHOR)
Hernandez, Victor (AUTHOR)
Diwan, Gaurav D. (AUTHOR)
Russell, Robert B. (AUTHOR)
Ueffing, Marius (AUTHOR)
Huranova, Martina (AUTHOR)
Boldt, Karsten (AUTHOR)
Beales, Philip L. (AUTHOR)
Jenkins, Dagan (AUTHOR)
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Źródło:
Cells (2073-4409). Nov2023, Vol. 12 Issue 22, p2662. 21p.
Czasopismo naukowe
Tytuł:
Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation.
Autorzy:
Ailenberg, M
Di Ciano-Oliveira, C
Szaszi, K
Dan, Q
Rozycki, M
Kapus, A
Rotstein, O D
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Temat:
PROTEIN metabolism
REACTIVE oxygen species
ANIMAL experimentation
CARRIER proteins
CELL lines
CELL receptors
CELLULAR signal transduction
COMPARATIVE studies
ENDOCYTOSIS
INTERFERONS
RESEARCH methodology
MEDICAL cooperation
MICE
ORGANIC compounds
RESEARCH
DNA-binding proteins
EVALUATION research
Źródło:
British Journal of Pharmacology; Aug2015, Vol. 172 Issue 15, p3748-3763, 16p
Czasopismo naukowe
Tytuł:
Identification of BRCC3 and BRCA1 as Regulators of TAZ Stability and Activity.
Autorzy:
Sberna, Silvia (AUTHOR)
Lopez-Hernandez, Alejandro (AUTHOR)
Biancotto, Chiara (AUTHOR)
Motta, Luca (AUTHOR)
Andronache, Adrian (AUTHOR)
Verhoef, Lisette G. G. C. (AUTHOR)
Caganova, Marieta (AUTHOR)
Campaner, Stefano (AUTHOR)
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Źródło:
Cells (2073-4409). Oct2023, Vol. 12 Issue 20, p2431. 22p.
Czasopismo naukowe
Tytuł:
Effects of nebulized hypertonic saline on inflammatory mediators in patients with severe COVID-19 pneumonia: A double-blinded randomized controlled trial.
Autorzy:
Beigmohammadi, Mohammad-Taghi (AUTHOR)
Amoozadeh, Laya (AUTHOR)
Naghibi, Nikoosadat (AUTHOR)
Eslami, Babak (AUTHOR)
Fattah Ghazi, Samrand (AUTHOR)
Javaherian, Mohammad (AUTHOR)
Khajeh-Azad, Mohammad-Amin (AUTHOR)
Tabatabaei, Bahram (AUTHOR)
Abdollahi, Alireza (AUTHOR)
Nazar, Elham (AUTHOR)
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Źródło:
Science Progress. Oct-Dec2023, Vol. 106 Issue 4, p1-13. 13p.
Czasopismo naukowe
Tytuł:
Beneficial Effects of Lactobacilli Species on Intestinal Homeostasis in Low-Grade Inflammation and Stress Rodent Models and Their Implication in the Modulation of the Adhesive Junctional Complex.
Autorzy:
Chamignon, Célia (AUTHOR)
Mallaret, Geoffroy (AUTHOR)
Rivière, Julie (AUTHOR)
Vilotte, Marthe (AUTHOR)
Chadi, Sead (AUTHOR)
de Moreno de LeBlanc, Alejandra (AUTHOR)
LeBlanc, Jean Guy (AUTHOR)
Carvalho, Frédéric Antonio (AUTHOR)
Pane, Marco (AUTHOR)
Mousset, Pierre-Yves (AUTHOR)
Langella, Philippe (AUTHOR)
Lafay, Sophie (AUTHOR)
Bermúdez-Humarán, Luis G. (AUTHOR)
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Źródło:
Biomolecules (2218-273X). Sep2023, Vol. 13 Issue 9, p1295. 21p.
Czasopismo naukowe

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