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Wyświetlanie 1-20 z 2176
Tytuł:
Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation.
Autorzy:
Gopal K; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Karwi QG; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.
Tabatabaei Dakhili SA; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Wagg CS; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.
Zhang L; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.
Sun Q; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.
Saed CT; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Panidarapu S; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.
Perfetti R; Applied Therapeutics, New York, NY, USA.
Ramasamy R; Diabetes Research Program, New York University Grossman Medical Center, New York, NY, USA.
Ussher JR; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Lopaschuk GD; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada. .
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Źródło:
Cardiovascular diabetology [Cardiovasc Diabetol] 2023 Mar 28; Vol. 22 (1), pp. 73. Date of Electronic Publication: 2023 Mar 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/metabolism
Diabetic Cardiomyopathies*/drug therapy
Diabetic Cardiomyopathies*/etiology
Diabetic Cardiomyopathies*/prevention & control
Animals ; Male ; Mice ; Aldehyde Reductase/metabolism ; Fatty Acids/metabolism ; Mice, Inbred C57BL ; Myocardium/metabolism ; Disease Models, Animal ; Random Allocation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The anti-anginal ranolazine does not confer beneficial actions against hepatic steatosis in male mice subjected to high-fat diet and streptozotocin-induced type 2 diabetes.
Autorzy:
Saed CT; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Centre, University of Alberta, Edmonton, AB, Canada.
Greenwell AA; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Centre, University of Alberta, Edmonton, AB, Canada.
Tabatabaei Dakhili SA; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Centre, University of Alberta, Edmonton, AB, Canada.
Gopal K; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Centre, University of Alberta, Edmonton, AB, Canada.
Eaton F; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Centre, University of Alberta, Edmonton, AB, Canada.
Ussher JR; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Centre, University of Alberta, Edmonton, AB, Canada.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2022 May; Vol. 100 (5), pp. 393-401. Date of Electronic Publication: 2021 Dec 01.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Insulin Resistance*
Non-alcoholic Fatty Liver Disease*/drug therapy
Animals ; Blood Glucose ; Diet, High-Fat/adverse effects ; Liver ; Male ; Mice ; Mice, Inbred C57BL ; Obesity/complications ; Obesity/drug therapy ; Ranolazine/pharmacology ; Ranolazine/therapeutic use ; Streptozocin ; Triglycerides
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evidence that tirzepatide protects against diabetes-related cardiac damages.
Autorzy:
Taktaz, Fatemeh (AUTHOR)
Scisciola, Lucia (AUTHOR)
Fontanella, Rosaria Anna (AUTHOR)
Pesapane, Ada (AUTHOR)
Ghosh, Puja (AUTHOR)
Franzese, Martina (AUTHOR)
Tortorella, Giovanni (AUTHOR)
Puocci, Armando (AUTHOR)
Sommella, Eduardo (AUTHOR)
Signoriello, Giuseppe (AUTHOR)
Olivieri, Fabiola (AUTHOR)
Barbieri, Michelangela (AUTHOR)
Paolisso, Giuseppe (AUTHOR)
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Źródło:
Cardiovascular Diabetology. 3/30/2024, Vol. 23 Issue 1, p1-15. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A genetic mouse model of lean-NAFLD unveils sexual dimorphism in the liver-heart axis.
Autorzy:
Burelle, Charlotte (AUTHOR)
Clapatiuc, Valentin (AUTHOR)
Deschênes, Sonia (AUTHOR)
Cuillerier, Alexanne (AUTHOR)
De Loof, Marine (AUTHOR)
Higgins, Marie-Ève (AUTHOR)
Boël, Hugues (AUTHOR)
Daneault, Caroline (AUTHOR)
Chouinard, Billie (AUTHOR)
Clavet, Marie-Élaine (AUTHOR)
Tessier, Nolwenn (AUTHOR)
Croteau, Isabelle (AUTHOR)
Chabot, Geneviève (AUTHOR)
Martel, Catherine (AUTHOR)
Sirois, Martin G. (AUTHOR)
Lesage, Sylvie (AUTHOR)
Burelle, Yan (AUTHOR)
Ruiz, Matthieu (AUTHOR)
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Źródło:
Communications Biology. 3/22/2024, Vol. 7 Issue 1, p1-19. 19p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Underlying mechanisms and cardioprotective effects of SGLT2i and GLP-1Ra: insights from cardiovascular magnetic resonance.
Autorzy:
Cersosimo, Angelica (AUTHOR)
Salerno, Nadia (AUTHOR)
Sabatino, Jolanda (AUTHOR)
Scatteia, Alessandra (AUTHOR)
Bisaccia, Giandomenico (AUTHOR)
De Rosa, Salvatore (AUTHOR)
Dellegrottaglie, Santo (AUTHOR)
Bucciarelli-Ducci, Chiara (AUTHOR)
Torella, Daniele (AUTHOR)
Leo, Isabella (AUTHOR)
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Źródło:
Cardiovascular Diabetology. 3/14/2024, Vol. 23 Issue 1, p1-13. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Real-World Use of Oral Semaglutide in Adults with Type 2 Diabetes: The PIONEER REAL Switzerland Multicentre, Prospective, Observational Study.
Autorzy:
Kick, Anastas (AUTHOR)
M'Rabet-Bensalah, Khadija (AUTHOR)
Acquistapace, Flavio (AUTHOR)
Amadid, Hanan (AUTHOR)
Ambühl, Robert A. (AUTHOR)
Braae, Uffe Christian (AUTHOR)
Item, Flurin (AUTHOR)
Schultes, Bernd (AUTHOR)
Züger, Thomas (AUTHOR)
Rudofsky, Gottfried (AUTHOR)
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Źródło:
Diabetes Therapy. Mar2024, Vol. 15 Issue 3, p623-637. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Circulating exosomal mir-16-2-3p is associated with coronary microvascular dysfunction in diabetes through regulating the fatty acid degradation of endothelial cells.
Autorzy:
Liu, Yihai (AUTHOR)
Zhong, Chongxia (AUTHOR)
Chen, Shan (AUTHOR)
Xue, Yanan (AUTHOR)
Wei, Zhonghai (AUTHOR)
Dong, Li (AUTHOR)
Kang, Lina (AUTHOR)
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Źródło:
Cardiovascular Diabetology. 2/9/2024, Vol. 23 Issue 1, p1-15. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
亚精胺通过改善心脏线粒体能量代谢缓解 压力超负荷小鼠心力衰竭.
Autorzy:
张晓亮
赵晓玲
耿 静
胡 朗
李 妍
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Alternatywny tytuł:
Spermidine alleviates pressure overload-induced heart failure in mice via improving cardiac mitochondrial energy metabolism.
Źródło:
Chinese Journal of Pathophysiology. Feb2024, Vol. 40 Issue 2, p193-203. 11p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure.
Autorzy:
Uddin GM; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.
Zhang L; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.
Shah S; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.
Fukushima A; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.
Wagg CS; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.
Gopal K; Katz Centre for Pharmacy and Health Research, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Canada.; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, Canada.
Al Batran R; Katz Centre for Pharmacy and Health Research, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Canada.; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, Canada.
Pherwani S; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.
Ho KL; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.; Katz Centre for Pharmacy and Health Research, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Canada.
Boisvenue J; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.
Karwi QG; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.; Department of Pharmacology, College of Medicine, University of Diyala, Diyala, Iraq.
Altamimi T; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.
Wishart DS; Department of Biological Sciences, University of Alberta, Edmonton, Canada.; Metabolomics Innovation Centre, University of Alberta, Edmonton, Canada.
Dyck JRB; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.
Ussher JR; Katz Centre for Pharmacy and Health Research, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Canada.; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, Canada.
Oudit GY; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada.; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.; Divsion of Cardiology, Department of Medicine, University of Alberta, Edmonton, Canada.
Lopaschuk GD; Cardiovascular Research Centre, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, T6G 2S2, Canada. .; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada. .; Alberta Diabetes Institute, University of Alberta, Edmonton, Canada. .
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Źródło:
Cardiovascular diabetology [Cardiovasc Diabetol] 2019 Jul 05; Vol. 18 (1), pp. 86. Date of Electronic Publication: 2019 Jul 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin Resistance*
Amino Acids, Branched-Chain/*metabolism
Cardiomyopathy, Dilated/*complications
Energy Metabolism/*drug effects
Heart Failure/*etiology
Myocardium/*metabolism
Adult ; Aged ; Animals ; Carboxylic Acids/pharmacology ; Cardiomyopathy, Dilated/metabolism ; Cardiomyopathy, Dilated/physiopathology ; Case-Control Studies ; Disease Models, Animal ; Female ; Fibrosis ; Heart Failure/drug therapy ; Heart Failure/metabolism ; Heart Failure/pathology ; Humans ; Male ; Mice, Inbred C57BL ; Middle Aged ; Myocardium/pathology ; Oxidation-Reduction ; Protein Kinase Inhibitors/pharmacology ; Protein Kinases/metabolism ; Signal Transduction/drug effects ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction.
Autorzy:
Karwi QG; Cardiovascular Research Centre, 423 Heritage Medical Research Centre, University of Alberta, Edmonton, AB, T6G 2S2, Canada.; Department of Pharmacology, College of Medicine, University of Diyala, Diyala, Iraq.
Zhang L; Cardiovascular Research Centre, 423 Heritage Medical Research Centre, University of Alberta, Edmonton, AB, T6G 2S2, Canada.
Wagg CS; Cardiovascular Research Centre, 423 Heritage Medical Research Centre, University of Alberta, Edmonton, AB, T6G 2S2, Canada.
Wang W; Cardiovascular Research Centre, 423 Heritage Medical Research Centre, University of Alberta, Edmonton, AB, T6G 2S2, Canada.
Ghandi M; Cardiovascular Research Centre, 423 Heritage Medical Research Centre, University of Alberta, Edmonton, AB, T6G 2S2, Canada.
Thai D; REMD Biotherapeutics Inc., Camarillo, CA, USA.; Cosci-REMD Biotherapeutics Inc, Beijing, China.
Yan H; REMD Biotherapeutics Inc., Camarillo, CA, USA.; Cosci-REMD Biotherapeutics Inc, Beijing, China.
Ussher JR; Cardiovascular Research Centre, 423 Heritage Medical Research Centre, University of Alberta, Edmonton, AB, T6G 2S2, Canada.
Oudit GY; Cardiovascular Research Centre, 423 Heritage Medical Research Centre, University of Alberta, Edmonton, AB, T6G 2S2, Canada.
Lopaschuk GD; Cardiovascular Research Centre, 423 Heritage Medical Research Centre, University of Alberta, Edmonton, AB, T6G 2S2, Canada. .
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Źródło:
Cardiovascular diabetology [Cardiovasc Diabetol] 2019 Jan 09; Vol. 18 (1), pp. 1. Date of Electronic Publication: 2019 Jan 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin Resistance*
Antibodies, Monoclonal/*pharmacology
Myocardial Infarction/*drug therapy
Myocardium/*metabolism
Receptors, Glucagon/*antagonists & inhibitors
Stroke Volume/*drug effects
Ventricular Function, Left/*drug effects
Animals ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Disease Models, Animal ; Energy Metabolism/drug effects ; Isolated Heart Preparation ; Male ; Mice, Inbred C57BL ; Myocardial Infarction/metabolism ; Myocardial Infarction/physiopathology ; Receptors, Glucagon/metabolism ; Recovery of Function ; Signal Transduction/drug effects ; Ventricular Remodeling/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Semaglutide modulates prothrombotic and atherosclerotic mechanisms, associated with epicardial fat, neutrophils and endothelial cells network.
Autorzy:
García-Vega, David (AUTHOR)
Sánchez-López, David (AUTHOR)
Rodríguez-Carnero, Gemma (AUTHOR)
Villar-Taibo, Rocío (AUTHOR)
Viñuela, Juan E. (AUTHOR)
Lestegás-Soto, Adán (AUTHOR)
Seoane-Blanco, Ana (AUTHOR)
Moure-González, María (AUTHOR)
Bravo, Susana B. (AUTHOR)
Fernández, Ángel L. (AUTHOR)
González-Juanatey, José R. (AUTHOR)
Eiras, Sonia (AUTHOR)
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Źródło:
Cardiovascular Diabetology. 1/3/2024, Vol. 23 Issue 1, p1-18. 18p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
COX6A2 deficiency leads to cardiac remodeling in human pluripotent stem cell-derived cardiomyocytes.
Autorzy:
Jiang, Mengqi (AUTHOR)
Song, Yuanxiu (AUTHOR)
Chen, Xi (AUTHOR)
Lu, Wenjing (AUTHOR)
Zhu, Min (AUTHOR)
Wei, Mingyu (AUTHOR)
Lan, Feng (AUTHOR)
Cui, Ming (AUTHOR)
Bai, Yun (AUTHOR)
Pokaż więcej
Źródło:
Stem Cell Research & Therapy. 12/10/2023, Vol. 14 Issue 1, p1-17. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of diabetes mellitus and glycemic traits on cardiovascular morpho-functional phenotypes.
Autorzy:
Li, Zhaoyue (AUTHOR)
Xiong, Jie (AUTHOR)
Guo, Yutong (AUTHOR)
Tang, Hao (AUTHOR)
Guo, Bingchen (AUTHOR)
Wang, Bo (AUTHOR)
Gao, Dianyu (AUTHOR)
Dong, Zengxiang (AUTHOR)
Tu, Yingfeng (AUTHOR)
Pokaż więcej
Źródło:
Cardiovascular Diabetology. 12/8/2023, Vol. 22 Issue 1, p1-12. 12p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 2176

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