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Wyświetlanie 1-20 z 3603
Tytuł:
Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours.
Autorzy:
Geurts BS; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
Battaglia TW; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
van Berge Henegouwen JM; Oncode Institute, Utrecht, the Netherlands.; Department of Medical Oncology, Leiden University Medical Centre, Leiden, the Netherlands.
Zeverijn LJ; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
de Wit GF; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
Hoes LR; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.
van der Wijngaart H; Oncode Institute, Utrecht, the Netherlands.; Department of Medical Oncology, Amsterdam University Medical Centre, location VUMC, Amsterdam, the Netherlands.
van der Noort V; Department of Biometrics, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Roepman P; Hartwig Medical Foundation, Amsterdam, the Netherlands.
de Leng WWJ; Department of Pathology, University Medical Cancer Centre Utrecht, Utrecht, the Netherlands.
Jansen AML; Department of Pathology, University Medical Cancer Centre Utrecht, Utrecht, the Netherlands.
Opdam FL; Department of Clinical Pharmacology, the Netherlands Cancer Institute, Amsterdam, the Netherlands.
de Jonge MJA; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Cirkel GA; Department of Medical Oncology, Meander, Amersfoort, the Netherlands.
Labots M; Department of Medical Oncology, Amsterdam University Medical Centre, location VUMC, Amsterdam, the Netherlands.
Hoeben A; Department of Medical Oncology, Department of Internal Medicine, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Kerver ED; Department of Medical Oncology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands.
Bins AD; Department of Medical Oncology, Amsterdam University Medical Centre, location AUMC, Amsterdam, the Netherlands.
Erdkamp FGL; Department of Medical Oncology, Zuyderland Hospital, Sittard-Geelen, the Netherlands.
van Rooijen JM; Department of Medical Oncology, Martini Hospital, Groningen, the Netherlands.
Houtsma D; Department of Medical Oncology, Haga Hospital, The Hague, the Netherlands.
Hendriks MP; Department of Medical Oncology, Northwest Clinics, Alkmaar, the Netherlands.
de Groot JB; Department of Medical Oncology, Isala, Zwolle, the Netherlands.
Verheul HMW; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Gelderblom H; Department of Medical Oncology, Leiden University Medical Centre, Leiden, the Netherlands.
Voest EE; Division of Molecular Oncology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands. e.voest@nki.nl.; Oncode Institute, Utrecht, the Netherlands. e.voest@nki.nl.
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Źródło:
BMC cancer [BMC Cancer] 2023 Mar 04; Vol. 23 (1), pp. 205. Date of Electronic Publication: 2023 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Microsatellite Instability*
Brain Neoplasms*
Humans ; Biomarkers
SCR Disease Name:
Turcot syndrome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical Impact of Prospective Whole Genome Sequencing in Sarcoma Patients.
Autorzy:
Schipper LJ; Department of Molecular Oncology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands.
Monkhorst K; Department of Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Samsom KG; Department of Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Bosch LJW; Department of Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Snaebjornsson P; Department of Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
van Boven H; Department of Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Roepman P; Hartwig Medical Foundation, 1098 XH Amsterdam, The Netherlands.
van der Kolk LE; Family Cancer Clinic, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
van Houdt WJ; Department of Surgical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
van der Graaf WTA; Department of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Meijer GA; Department of Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Voest EE; Department of Molecular Oncology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.; Oncode Institute, 3521 AL Utrecht, The Netherlands.; Department of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
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Źródło:
Cancers [Cancers (Basel)] 2022 Jan 16; Vol. 14 (2). Date of Electronic Publication: 2022 Jan 16.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE).
Autorzy:
Samsom KG; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Bosch LJW; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Schipper LJ; Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Roepman P; Hartwig Medical Foundation, Amsterdam, The Netherlands.
de Bruijn E; Hartwig Medical Foundation, Amsterdam, The Netherlands.
Hoes LR; Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Riethorst I; Hartwig Medical Foundation, Amsterdam, The Netherlands.
Schoenmaker L; Hartwig Medical Foundation, Amsterdam, The Netherlands.
van der Kolk LE; Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Retèl VP
Frederix GWJ
Buffart TE; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
van der Hoeven JJM; Hartwig Medical Foundation, Amsterdam, The Netherlands.
Voest EE; Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
Cuppen E; Hartwig Medical Foundation, Amsterdam, The Netherlands.; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
Monkhorst K; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands. .
Meijer GA; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
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Źródło:
BMC medical genomics [BMC Med Genomics] 2020 Nov 10; Vol. 13 (1), pp. 169. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji:
Clinical Trial Protocol; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Molecular Diagnostic Techniques*/economics
Molecular Diagnostic Techniques*/methods
Whole Genome Sequencing*/economics
Whole Genome Sequencing*/methods
Neoplasms/*diagnosis
Precision Medicine/*methods
Biomarkers, Tumor/analysis ; Biomarkers, Tumor/genetics ; Clinical Decision-Making ; DNA, Neoplasm/genetics ; Feasibility Studies ; Humans ; Neoplasms/chemistry ; Neoplasms/genetics ; Observational Studies as Topic ; Patient Selection ; Research Design ; Specimen Handling/methods ; Standard of Care ; Technology Assessment, Biomedical ; Workflow
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition.
Autorzy:
Deben, Christophe (AUTHOR)
Boullosa, Laurie Freire (AUTHOR)
Fortes, Felicia Rodrigues (AUTHOR)
De La Hoz, Edgar Cardenas (AUTHOR)
Le Compte, Maxim (AUTHOR)
Seghers, Sofie (AUTHOR)
Peeters, Marc (AUTHOR)
Vanlanduit, Steve (AUTHOR)
Lin, Abraham (AUTHOR)
Dijkstra, Krijn K. (AUTHOR)
Van Schil, Paul (AUTHOR)
Hendriks, Jeroen M. H. (AUTHOR)
Prenen, Hans (AUTHOR)
Roeyen, Geert (AUTHOR)
Lardon, Filip (AUTHOR)
Smits, Evelien (AUTHOR)
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Źródło:
Journal of Experimental & Clinical Cancer Research (17569966). 3/22/2024, Vol. 43 Issue 1, p1-15. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine.
Autorzy:
Jose, Anmi (AUTHOR)
Kulkarni, Pallavi (AUTHOR)
Thilakan, Jaya (AUTHOR)
Munisamy, Murali (AUTHOR)
Malhotra, Anvita Gupta (AUTHOR)
Singh, Jitendra (AUTHOR)
Kumar, Ashok (AUTHOR)
Rangnekar, Vivek M. (AUTHOR)
Arya, Neha (AUTHOR)
Rao, Mahadev (AUTHOR)
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Źródło:
Molecular Cancer. 3/9/2024, Vol. 23 Issue 1, p1-24. 24p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Organoids derived from patients provide a new opportunity for research and individualized treatment of malignant peritoneal mesothelioma.
Autorzy:
Fang, XiaoChang (AUTHOR)
Shu, Lin (AUTHOR)
Chen, TianLiang (AUTHOR)
Zhao, XiaoLe (AUTHOR)
Yang, LiuCui (AUTHOR)
Dou, Tingting (AUTHOR)
Yang, Lijie (AUTHOR)
Li, Xuanfei (AUTHOR)
Feng, Maohui (AUTHOR)
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Źródło:
Molecular Cancer. 1/10/2024, Vol. 23 Issue 1, p1-21. 21p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Magnitude of effect and sample size justification in trials supporting anti-cancer drug approval by the US Food and Drug Administration.
Autorzy:
Nadler, Michelle B. (AUTHOR)
Wilson, Brooke E. (AUTHOR)
Desnoyers, Alexandra (AUTHOR)
Valiente, Consolacion Molto (AUTHOR)
Saleh, Ramy R. (AUTHOR)
Amir, Eitan (AUTHOR)
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Źródło:
Scientific Reports. 1/3/2024, Vol. 13 Issue 1, p1-9. 9p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Precision nephrotoxicity testing using 3D in vitro models.
Autorzy:
Yu, Pengfei (AUTHOR)
Zhu, Hainan (AUTHOR)
Bosholm, Carol Christine (AUTHOR)
Beiner, Daniella (AUTHOR)
Duan, Zhongping (AUTHOR)
Shetty, Avinash K. (AUTHOR)
Mou, Steve S. (AUTHOR)
Kramer, Philip Adam (AUTHOR)
Barroso, Luis F. (AUTHOR)
Liu, Hongbing (AUTHOR)
Cheng, Kun (AUTHOR)
Ihnat, Michael (AUTHOR)
Gorris, Matthew A. (AUTHOR)
Aloi, Joseph A. (AUTHOR)
Woldemichael, Jobira A. (AUTHOR)
Bleyer, Anthony (AUTHOR)
Zhang, Yuanyuan (AUTHOR)
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Źródło:
Cell & Bioscience. 12/21/2023, Vol. 13 Issue 1, p1-16. 16p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Symptom clusters associated with complementary and alternative medicine use by cancer patients: A cross-sectional study.
Autorzy:
Huemer, Matthias (AUTHOR)
Pansi, Anna (AUTHOR)
Hofmann, Guenter (AUTHOR)
Terbuch, Angelika (AUTHOR)
Sciri, Elisabeth (AUTHOR)
Lipp, Rainer (AUTHOR)
Spiegelberg, Jasmin Alija (AUTHOR)
Jahn-Kuch, Daniela (AUTHOR)
Pichler, Martin (AUTHOR)
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Źródło:
PLoS ONE. 12/14/2023, Vol. 18 Issue 12, p1-16. 16p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative analysis of response to treatments and molecular features of tumor-derived organoids versus cell lines and PDX derived from the same ovarian clear cell carcinoma.
Autorzy:
Thorel, Lucie (AUTHOR)
Morice, Pierre-Marie (AUTHOR)
Paysant, Hippolyte (AUTHOR)
Florent, Romane (AUTHOR)
Babin, Guillaume (AUTHOR)
Thomine, Cécilia (AUTHOR)
Perréard, Marion (AUTHOR)
Abeilard, Edwige (AUTHOR)
Giffard, Florence (AUTHOR)
Brotin, Emilie (AUTHOR)
Denoyelle, Christophe (AUTHOR)
Villenet, Céline (AUTHOR)
Sebda, Shéhérazade (AUTHOR)
Briand, Mélanie (AUTHOR)
Joly, Florence (AUTHOR)
Dolivet, Enora (AUTHOR)
Goux, Didier (AUTHOR)
Blanc-Fournier, Cécile (AUTHOR)
Jeanne, Corinne (AUTHOR)
Villedieu, Marie (AUTHOR)
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Źródło:
Journal of Experimental & Clinical Cancer Research (17569966). 11/21/2023, Vol. 42 Issue 1, p1-17. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
External mechanical loading overrules cell-cell mechanical communication in sprouting angiogenesis during early bone regeneration.
Autorzy:
Dazzi, Chiara (AUTHOR)
Mehl, Julia (AUTHOR)
Benamar, Mounir (AUTHOR)
Gerhardt, Holger (AUTHOR)
Knaus, Petra (AUTHOR)
Duda, Georg N. (AUTHOR)
Checa, Sara (AUTHOR)
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Źródło:
PLoS Computational Biology. 11/13/2023, Vol. 19 Issue 11, p1-27. 27p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 3603

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