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Tytuł:
Ensemble-imbalance-based classification for amyotrophic lateral sclerosis prognostic prediction: identifying short-survival patients at diagnosis.
Autorzy:
Papaiz F; Federal University of Rio Grande Do Norte, Natal, Brazil. .; University of Coimbra, Coimbra, Portugal. .; Federal Institute of Rio Grande Do Norte, Natal, Brazil. .
Dourado MET Jr; Federal University of Rio Grande Do Norte, Natal, Brazil.
de Medeiros Valentim RA; Federal University of Rio Grande Do Norte, Natal, Brazil.
Pinto R; Federal University of Rio Grande Do Norte, Natal, Brazil.; Federal Institute of Rio Grande Do Norte, Natal, Brazil.
de Morais AHF; Federal Institute of Rio Grande Do Norte, Natal, Brazil.
Arrais JP; University of Coimbra, Coimbra, Portugal.
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Źródło:
BMC medical informatics and decision making [BMC Med Inform Decis Mak] 2024 Mar 19; Vol. 24 (1), pp. 80. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/diagnosis
Amyotrophic Lateral Sclerosis*/drug therapy
Humans ; Prognosis ; Machine Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neurite orientation dispersion and density imaging quantifies microstructural impairment in the thalamus and its connectivity in amyotrophic lateral sclerosis.
Autorzy:
Cao YB; Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, China.
Wu Y; School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing, China.
Dong QY; Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, China.
Huang NX; Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, China.
Zou ZY; Department of Neurology, Fujian Medical University Union Hospital, Fuzhou, China.
Chen HJ; Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14616.
Typ publikacji:
Journal Article
MeSH Terms:
Neurites*
Amyotrophic Lateral Sclerosis*/diagnostic imaging
Humans ; Diffusion Tensor Imaging/methods ; Thalamus/diagnostic imaging ; Neural Pathways/diagnostic imaging
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sporadic Amyotrophic Lateral Sclerosis Skeletal Muscle Transcriptome Analysis: A Comprehensive Examination of Differentially Expressed Genes.
Autorzy:
Gascón E; Department of Anatomy, Embryology and Animal Genetics, University of Zaragoza, 50013 Zaragoza, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 28029 Madrid, Spain.; Agroalimentary Institute of Aragon (IA2), University of Zaragoza, 50013 Zaragoza, Spain.; Institute of Health Research of Aragon (IIS), 50009 Zaragoza, Spain.
Zaragoza P; Department of Anatomy, Embryology and Animal Genetics, University of Zaragoza, 50013 Zaragoza, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 28029 Madrid, Spain.; Agroalimentary Institute of Aragon (IA2), University of Zaragoza, 50013 Zaragoza, Spain.; Institute of Health Research of Aragon (IIS), 50009 Zaragoza, Spain.
Calvo AC; Department of Anatomy, Embryology and Animal Genetics, University of Zaragoza, 50013 Zaragoza, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 28029 Madrid, Spain.; Agroalimentary Institute of Aragon (IA2), University of Zaragoza, 50013 Zaragoza, Spain.; Institute of Health Research of Aragon (IIS), 50009 Zaragoza, Spain.
Osta R; Department of Anatomy, Embryology and Animal Genetics, University of Zaragoza, 50013 Zaragoza, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 28029 Madrid, Spain.; Agroalimentary Institute of Aragon (IA2), University of Zaragoza, 50013 Zaragoza, Spain.; Institute of Health Research of Aragon (IIS), 50009 Zaragoza, Spain.
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Źródło:
Biomolecules [Biomolecules] 2024 Mar 20; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 20.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/genetics
Amyotrophic Lateral Sclerosis*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Humans ; Transcriptome/genetics ; Muscle, Skeletal/metabolism ; Biomarkers
SCR Disease Name:
Amyotrophic lateral sclerosis 1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro.
Autorzy:
Duan QQ; Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Institute of Brain Science and Brain-Inspired Technology, West China Hospital, Sichuan University, Sichuan, Chengdu,, 610041, China.; Rare Disease Center, West China Hospital, Sichuan University, Sichuan, Chengdu, 610041, China.
Wang H; Department of Pathophysiology, West China College of Basic Medical Sciences and Forensic Medicine, Sichuan University, Sichuan, Chengdu, 610041, China.
Su WM; Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Institute of Brain Science and Brain-Inspired Technology, West China Hospital, Sichuan University, Sichuan, Chengdu,, 610041, China.; Rare Disease Center, West China Hospital, Sichuan University, Sichuan, Chengdu, 610041, China.
Gu XJ; Mental Health Center, West China Hospital, Sichuan University, Sichuan, Chengdu, 610041, China.
Shen XF; TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China.
Jiang Z; Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Institute of Brain Science and Brain-Inspired Technology, West China Hospital, Sichuan University, Sichuan, Chengdu,, 610041, China.; Rare Disease Center, West China Hospital, Sichuan University, Sichuan, Chengdu, 610041, China.
Ren YL; Department of Pathophysiology, West China College of Basic Medical Sciences and Forensic Medicine, Sichuan University, Sichuan, Chengdu, 610041, China.
Cao B; Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Institute of Brain Science and Brain-Inspired Technology, West China Hospital, Sichuan University, Sichuan, Chengdu,, 610041, China.; Rare Disease Center, West China Hospital, Sichuan University, Sichuan, Chengdu, 610041, China.
Li GB; Key Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, 610041, China.
Wang Y; Department of Pathophysiology, West China College of Basic Medical Sciences and Forensic Medicine, Sichuan University, Sichuan, Chengdu, 610041, China. .
Chen YP; Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China. .; Institute of Brain Science and Brain-Inspired Technology, West China Hospital, Sichuan University, Sichuan, Chengdu,, 610041, China. .; Rare Disease Center, West China Hospital, Sichuan University, Sichuan, Chengdu, 610041, China. .
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Źródło:
BMC medicine [BMC Med] 2024 Mar 05; Vol. 22 (1), pp. 96. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/drug therapy
Amyotrophic Lateral Sclerosis*/genetics
Aminopyridines*
Humans ; Drug Repositioning ; Mendelian Randomization Analysis ; Protein Serine-Threonine Kinases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Trimetazidine Improves Mitochondrial Dysfunction in SOD1 Cellular Models of Amyotrophic Lateral Sclerosis through Autophagy Activation.
Autorzy:
Salvatori I; Department of Experimental Medicine, University of Roma 'La Sapienza', 00185 Rome, Italy.; IRCCS, Fondazione Santa Lucia, 00179 Rome, Italy.
Nesci V; IRCCS, Fondazione Santa Lucia, 00179 Rome, Italy.; Department of Systems Medicine, Tor Vergata University of Rome, 00133 Rome, Italy.
Spalloni A; IRCCS, Fondazione Santa Lucia, 00179 Rome, Italy.
Marabitti V; Department of Biology, Tor Vergata University of Rome, 00133 Rome, Italy.
Muzzi M; Department of Science, LIME, University of Roma Tre, 00165 Rome, Italy.
Zenuni H; Unit of Neurology, Fondazione PTV Policlinico Tor Vergata, 00133 Rome, Italy.
Scaricamazza S; IRCCS, Fondazione Santa Lucia, 00179 Rome, Italy.
Rosina M; IRCCS, Fondazione Santa Lucia, 00179 Rome, Italy.; Unit of Neurology, Fondazione PTV Policlinico Tor Vergata, 00133 Rome, Italy.
Fenili G; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', 00135 Rome, Italy.
Goglia M; Unit of Neurology, Fondazione PTV Policlinico Tor Vergata, 00133 Rome, Italy.
Boffa L; Unit of Neurology, Fondazione PTV Policlinico Tor Vergata, 00133 Rome, Italy.
Massa R; Unit of Neurology, Fondazione PTV Policlinico Tor Vergata, 00133 Rome, Italy.
Moreno S; Department of Science, LIME, University of Roma Tre, 00165 Rome, Italy.
Mercuri NB; IRCCS, Fondazione Santa Lucia, 00179 Rome, Italy.; Department of Systems Medicine, Tor Vergata University of Rome, 00133 Rome, Italy.; Unit of Neurology, Fondazione PTV Policlinico Tor Vergata, 00133 Rome, Italy.
Nazio F; Department of Biology, Tor Vergata University of Rome, 00133 Rome, Italy.
Longone P; IRCCS, Fondazione Santa Lucia, 00179 Rome, Italy.
Ferri A; IRCCS, Fondazione Santa Lucia, 00179 Rome, Italy.; Institute of Translational Pharmacology (IFT), National Research Council (CNR), 00133 Rome, Italy.
Valle C; IRCCS, Fondazione Santa Lucia, 00179 Rome, Italy.; Institute of Translational Pharmacology (IFT), National Research Council (CNR), 00133 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 13; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/metabolism
Trimetazidine*/pharmacology
Trimetazidine*/therapeutic use
Mitochondrial Diseases*
Mice ; Animals ; Humans ; Superoxide Dismutase-1/metabolism ; Mice, Transgenic ; Leukocytes, Mononuclear/metabolism ; Superoxide Dismutase/metabolism ; Autophagy ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Progressive Irreversible Proprioceptive Piezo2 Channelopathy-Induced Lost Forced Peripheral Oscillatory Synchronization to the Hippocampal Oscillator May Explain the Onset of Amyotrophic Lateral Sclerosis Pathomechanism.
Autorzy:
Sonkodi B; Department of Health Sciences and Sport Medicine, Hungarian University of Sports Science, 1123 Budapest, Hungary.; Department of Sports Medicine, Semmelweis University, 1122 Budapest, Hungary.
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Źródło:
Cells [Cells] 2024 Mar 12; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/metabolism
Channelopathies*
Neurodegenerative Diseases*
Humans ; Syndecan-3 ; Mechanotransduction, Cellular ; Protons ; Proprioception/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel insights into RAGE signaling pathways during the progression of amyotrophic lateral sclerosis in RAGE-deficient SOD1 G93A mice.
Autorzy:
Nowicka N; Department of Human Physiology and Pathophysiology, Faculty of Medicine, Collegium Medium, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Zglejc-Waszak K; Department of Human Physiology and Pathophysiology, Faculty of Medicine, Collegium Medium, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Juranek J; Department of Human Physiology and Pathophysiology, Faculty of Medicine, Collegium Medium, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Korytko A; Department of Human Physiology and Pathophysiology, Faculty of Medicine, Collegium Medium, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Wąsowicz K; Department of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Chmielewska-Krzesińska M; Department of Pathophysiology, Forensic Veterinary Medicine and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Wojtkiewicz J; Department of Human Physiology and Pathophysiology, Faculty of Medicine, Collegium Medium, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
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Źródło:
PloS one [PLoS One] 2024 Mar 08; Vol. 19 (3), pp. e0299567. Date of Electronic Publication: 2024 Mar 08 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/genetics
Amyotrophic Lateral Sclerosis*/metabolism
Amyotrophic Lateral Sclerosis*/pathology
Neurodegenerative Diseases*
Superoxide Dismutase-1*/genetics
Superoxide Dismutase-1*/metabolism
Animals ; Humans ; Mice ; Disease Models, Animal ; Disease Progression ; Mice, Transgenic ; Prospective Studies ; Receptor for Advanced Glycation End Products/genetics ; Signal Transduction ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cerebrospinal fluid and blood exosomes as biomarkers for amyotrophic lateral sclerosis; a systematic review.
Autorzy:
Darabi S; Cellular and Molecular Research Center, Research Institute for Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
Ariaei A; Student Research Committee, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Rustamzadeh A; Cellular and Molecular Research Center, Research Institute for Non-communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran. .; Department of Anatomical Sciences, School of Medicine, Iran University of Medical Sciences, Hemmat Highway, next to Milad Tower, Tehran, Iran. .
Afshari D; Department of Neurology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Charkhat Gorgich EA; Department of Anatomy, School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran.
Darabi L; Department of Neurology, Tehran Medical Science Branch, Amir Al Momenin Hospital, Islamic Azad University, Tehran, Iran.
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Źródło:
Diagnostic pathology [Diagn Pathol] 2024 Mar 01; Vol. 19 (1), pp. 47. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Systematic Review; Journal Article; Review
MeSH Terms:
Exosomes*
Amyotrophic Lateral Sclerosis*/diagnosis
Humans ; Superoxide Dismutase-1 ; Biomarkers ; DNA-Binding Proteins ; Disease Progression
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neuregulin-1 and ALS19 (ERBB4): at the crossroads of amyotrophic lateral sclerosis and cancer.
Autorzy:
Adashek JJ; Department of Oncology, The Johns Hopkins Hospital, The Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA. .
Pandya C; Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Department of Medicine, UC San Diego Moores Cancer Center, La Jolla, CA, USA.
Maragakis NJ; Department of Neurology, The Johns Hopkins Hospital, Baltimore, MD, USA.
De P; Cancer Genomics, Avera Cancer Institute, Sioux Falls, SD, USA.
Cohen PR; Department of Dermatology, Davis Medical Center, University of California, Sacramento, CA, USA.; Touro University California College of Osteopathic Medicine, Vallejo, CA, USA.
Kato S; Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Department of Medicine, UC San Diego Moores Cancer Center, La Jolla, CA, USA.
Kurzrock R; WIN Consortium, Paris, France. .; MCW Cancer Center, Milwaukee, WI, USA. .; University of Nebraska, Omaha, NE, USA. .
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Źródło:
BMC medicine [BMC Med] 2024 Feb 19; Vol. 22 (1), pp. 74. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amyotrophic Lateral Sclerosis*/genetics
Neoplasms*/genetics
Neuregulin-1*/genetics
Neuregulin-1*/metabolism
Receptor, ErbB-4*/genetics
Receptor, ErbB-4*/metabolism
Humans ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Accelerating drug development for amyotrophic lateral sclerosis: construction and application of a disease course model using historical placebo group data.
Autorzy:
Cai R; Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, No.1200 Cailun Road, Shanghai, 201203, China.
Yang J; Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, No.1200 Cailun Road, Shanghai, 201203, China.
Wu L; Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, No.1200 Cailun Road, Shanghai, 201203, China.
Liu Y; Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, No.1200 Cailun Road, Shanghai, 201203, China.
Wang X; Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, No.1200 Cailun Road, Shanghai, 201203, China.
Zheng Q; Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, No.1200 Cailun Road, Shanghai, 201203, China. .
Li L; Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, No.1200 Cailun Road, Shanghai, 201203, China. .; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. .
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Źródło:
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2024 Feb 02; Vol. 19 (1), pp. 40. Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/drug therapy
Humans ; Riluzole/therapeutic use ; Treatment Outcome ; Drug Development ; Disease Progression
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Can Some Anticancer Drugs Be Repurposed to Treat Amyotrophic Lateral Sclerosis? A Brief Narrative Review.
Autorzy:
Potenza RL; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Armida M; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Popoli P; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 01; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amyotrophic Lateral Sclerosis*/drug therapy
Motor Neuron Disease*
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stathmin 2 is a potential treatment target for TDP-43 proteinopathy in amyotrophic lateral sclerosis.
Autorzy:
Liu Y; Key Laboratory of Brain, Cognition and Education Sciences, South China Normal University, Ministry of Education, Guangzhou, China.; Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, 510631, China.
Yan D; Key Laboratory of Brain, Cognition and Education Sciences, South China Normal University, Ministry of Education, Guangzhou, China.; Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, 510631, China.
Yang L; Department of Anesthesiology, the Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou, China.; Rehabilitation Medicine Institute of Panyu District, Guangzhou, 511499, China.
Chen X; Key Laboratory of Brain, Cognition and Education Sciences, South China Normal University, Ministry of Education, Guangzhou, China.; Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, 510631, China.
Hu C; Key Laboratory of Brain, Cognition and Education Sciences, South China Normal University, Ministry of Education, Guangzhou, China. .; Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, 510631, China. .; Guangdong Second Provincial General Hospital, Guangzhou, 510317, China. .
Chen M; Guangdong Second Provincial General Hospital, Guangzhou, 510317, China. .
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Źródło:
Translational neurodegeneration [Transl Neurodegener] 2024 Apr 11; Vol. 13 (1), pp. 20. Date of Electronic Publication: 2024 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/complications
Stathmin*/antagonists & inhibitors
TDP-43 Proteinopathies*/drug therapy
Humans ; DNA-Binding Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Timing and impact of percutaneous endoscopic gastrostomy insertion in patients with amyotrophic lateral sclerosis: a comprehensive analysis.
Autorzy:
Son B; Cell Therapy Center, Hanyang University Seoul Hospital, 222-1 Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea.
Lee J; Department of Food and Nutrition, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea.
Ryu S; Biostatistical Consulting and Research Lab, Medical Research Collaborating Center, Hanyang University, Seoul, Korea.
Park Y; Department of Food and Nutrition, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea. .
Kim SH; Cell Therapy Center, Hanyang University Seoul Hospital, 222-1 Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea. .; Department of Neurology, Hanyang University Seoul Hospital, 222-1 Wangsimni-ro, Seongdong-gu, Seoul, 04763, Korea. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 26; Vol. 14 (1), pp. 7103. Date of Electronic Publication: 2024 Mar 26.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*
Deglutition Disorders*
Humans ; Gastrostomy/methods ; Retrospective Studies ; Weight Loss
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Amyotrophic Lateral Sclerosis and Pain: A Narrative Review from Pain Assessment to Therapy.
Autorzy:
Pota V; Department of Women, Child, General and Specialistic Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.
Sansone P; Department of Women, Child, General and Specialistic Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.
De Sarno S; Department of Women, Child, General and Specialistic Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.
Aurilio C; Department of Women, Child, General and Specialistic Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.
Coppolino F; Department of Women, Child, General and Specialistic Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.
Barbarisi M; Multidisciplinary Department of Medical, Surgical and Dental Specialties, University of Campania 'L. Vanvitelli', Naples, Italy.
Barbato F; Santa Maria delle Grazie Hospital, Pozzuoli, Naples, Italy.
Fiore M; Department of Women, Child, General and Specialistic Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.
Cosenza G; Department of Women, Child, General and Specialistic Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.
Passavanti MB; Department of Women, Child, General and Specialistic Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.
Pace MC; Department of Women, Child, General and Specialistic Surgery, University of Campania 'L. Vanvitelli', Naples, Italy.
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Źródło:
Behavioural neurology [Behav Neurol] 2024 Mar 16; Vol. 2024, pp. 1228194. Date of Electronic Publication: 2024 Mar 16 (Print Publication: 2024).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amyotrophic Lateral Sclerosis*/complications
Neurodegenerative Diseases*/complications
Humans ; Pain Measurement ; Quality of Life ; Pain/drug therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cellular and Noncellular Approaches for Repairing the Damaged Blood-CNS-Barrier in Amyotrophic Lateral Sclerosis.
Autorzy:
Manora L; Center of Excellence for Aging & Brain Repair, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., MDC 78, Tampa, FL 33612, USA.
Borlongan CV; Center of Excellence for Aging & Brain Repair, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., MDC 78, Tampa, FL 33612, USA.; Department of Neurosurgery and Brain Repair, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., MDC 78, Tampa, FL 33612, USA.
Garbuzova-Davis S; Center of Excellence for Aging & Brain Repair, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., MDC 78, Tampa, FL 33612, USA.; Department of Neurosurgery and Brain Repair, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd., MDC 78, Tampa, FL 33612, USA.
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Źródło:
Cells [Cells] 2024 Feb 29; Vol. 13 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amyotrophic Lateral Sclerosis*/metabolism
Neurodegenerative Diseases*/metabolism
Humans ; Endothelial Cells/metabolism ; Motor Neurons/metabolism ; Stem Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Detecting bulbar amyotrophic lateral sclerosis (ALS) using automatic acoustic analysis.
Autorzy:
Simmatis LER; KITE-Toronto Rehabilitation Institute, UHN, Toronto, ON, Canada. .; Department of Speech-Language Pathology, University of Toronto, Toronto, ON, Canada. .; Sunnybrook Research Institute, Toronto, ON, Canada. .
Robin J; Winterlight Labs, Inc., Toronto, ON, Canada.
Spilka MJ; Winterlight Labs, Inc., Toronto, ON, Canada.
Yunusova Y; KITE-Toronto Rehabilitation Institute, UHN, Toronto, ON, Canada.; Department of Speech-Language Pathology, University of Toronto, Toronto, ON, Canada.; Sunnybrook Research Institute, Toronto, ON, Canada.
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Źródło:
Biomedical engineering online [Biomed Eng Online] 2024 Feb 04; Vol. 23 (1), pp. 15. Date of Electronic Publication: 2024 Feb 04.
Typ publikacji:
Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/diagnosis
Humans ; Bayes Theorem ; Speech ; Speech Disorders/diagnosis ; ROC Curve
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Inflammatory Puzzle: Piecing together the Links between Neuroinflammation and Amyotrophic Lateral Sclerosis.
Autorzy:
He D; Department of Neurology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), Beijing, China.
Xu Y; Department of Neurology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), Beijing, China.
Liu M; Department of Neurology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), Beijing, China.
Cui L; Department of Neurology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), Beijing, China.
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Źródło:
Aging and disease [Aging Dis] 2024 Feb 01; Vol. 15 (1), pp. 96-114. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amyotrophic Lateral Sclerosis*/genetics
Neurodegenerative Diseases*/complications
Humans ; Neuroinflammatory Diseases ; Central Nervous System ; Signal Transduction/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Brain-Gut-Microbiota Axis in Amyotrophic Lateral Sclerosis: A Historical Overview and Future Directions.
Autorzy:
Chen S; Clinical Biobank Center, Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.; Neurosurgery Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.
Cai X; Clinical Biobank Center, Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.; Neurosurgery Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.
Lao L; Clinical Biobank Center, Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.; Neurosurgery Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.
Wang Y; Clinical Biobank Center, Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.; Neurosurgery Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.
Su H; Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau.
Sun H; Clinical Biobank Center, Microbiome Medicine Center, Department of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.; Neurosurgery Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China.; Key Laboratory of Mental Health of the Ministry of Education, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Southern Medical University, Guangzhou, China.
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Źródło:
Aging and disease [Aging Dis] 2024 Feb 01; Vol. 15 (1), pp. 74-95. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amyotrophic Lateral Sclerosis*/epidemiology
Neurodegenerative Diseases*/complications
Gastrointestinal Microbiome*/physiology
Humans ; Aged ; Child, Preschool ; Brain-Gut Axis ; Brain
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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