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Tytuł:
The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databases.
Autorzy:
Shi X; Department of Dermatology, Huashan Hospital, and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Chen Y; Human Phenome Institute, and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China Fudan University, Shanghai, China.
Shi M; Department of Thoracic Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Gao F; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, China.
Huang L; Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism & Integrative Biology, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, 200438, China.
Wang W; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, China.; MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Wei D; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, China.
Shi C; MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Yu Y; Human Phenome Institute, and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China Fudan University, Shanghai, China.
Xia X; Human Phenome Institute, and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China Fudan University, Shanghai, China.
Song N; Department of Nephrology, Zhongshan Hospital, Fudan University, Fudan Zhangjiang Institute, Shanghai, People's Republic of China.
Chen X; Department of Thoracic Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Distler JHW; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen, Nuremberg, Germany.
Lu C; MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China. .
Chen J; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, China. .; Center for Lung Transplantation, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. .
Wang J; Department of Dermatology, Huashan Hospital, and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China. .; Human Phenome Institute, and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, China Fudan University, Shanghai, China. .; Research Unit of Dissecting the Population Genetics and Developing New Technologies for Treatment and Prevention of Skin Phenotypes and Dermatological Diseases (2019RU058), Chinese Academy of Medical Sciences, Beijing, China. .; Institute of Rheumatology, Immunology and Allergy, Fudan University, Shanghai, China. .
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2024 Apr 03; Vol. 23 (1), pp. 98. Date of Electronic Publication: 2024 Apr 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Pulmonary Fibrosis*/genetics
Pulmonary Fibrosis*/metabolism
Pulmonary Fibrosis*/pathology
Humans ; Single-Cell Gene Expression Analysis ; Lipid Metabolism/genetics ; Endothelial Cells/metabolism ; Phospholipids/metabolism ; Cholesterol/metabolism ; Phosphatidylcholines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Assessment of myocardial fibrosis in patients with systemic sclerosis using [ Ga]Ga-FAPI-04-PET-CT.
Autorzy:
Treutlein C; Department of Radiology, Friedrich-Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
Distler JHW; Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Tascilar K; Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Fakhouri SC; Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Györfi AH; Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Atzinger A; Department of Nuclear Medicine, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Matei AE; Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Dees C; Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Büttner-Herold M; Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Kuwert T; Department of Nuclear Medicine, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Prante O; Department of Nuclear Medicine, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Bäuerle T; Department of Radiology, Friedrich-Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
Uder M; Department of Radiology, Friedrich-Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
Schett G; Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; Deutsches Zentrum Immuntherapie (DZI), FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Schmidkonz C; Department of Nuclear Medicine, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.; University of Applied Sciences Amberg-Weiden, Institute for Medical Engineering, 92637, Weiden, Germany.
Bergmann C; Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany. .; Deutsches Zentrum Immuntherapie (DZI), FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany. .
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Źródło:
European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2023 May; Vol. 50 (6), pp. 1629-1635. Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Gallium Radioisotopes*
Scleroderma, Systemic*/complications
Scleroderma, Systemic*/diagnostic imaging
Humans ; Positron Emission Tomography Computed Tomography ; Contrast Media ; Gadolinium ; Fibrosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Decline in forced vital capacity in subjects with systemic sclerosis-associated interstitial lung disease in the SENSCIS trial compared with healthy reference subjects.
Autorzy:
Maher TM; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. .; National Heart and Lung Institute, Imperial College, London, UK. .
Bourdin A; PhyMedExp, University of Montpellier, INSERM U1046, CNRS, UMR 9214, Montpellier, France.; Department of Respiratory Diseases, University of Montpellier, CHU Montpellier, Montpellier, France.
Volkmann ER; Department of Medicine, Division of Rheumatology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Vettori S; UOC Di Fisiopatologia E Riabilitazione Respiratoria, Ospedale Monaldi, Naples, Italy.
Distler JHW; Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Universitätsklinikum Erlangen, Erlangen, Germany.
Alves M; TA Inflammation Med, Boehringer Ingelheim International GmbH, Ingelheim, Germany.
Stock C; Global Biostatistics and Data Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim Am Rhein, Germany.
Distler O; Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
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Źródło:
Respiratory research [Respir Res] 2022 Jul 05; Vol. 23 (1), pp. 178. Date of Electronic Publication: 2022 Jul 05.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Lung Diseases, Interstitial*/diagnosis
Lung Diseases, Interstitial*/drug therapy
Lung Diseases, Interstitial*/etiology
Scleroderma, Systemic*/complications
Scleroderma, Systemic*/diagnosis
Scleroderma, Systemic*/drug therapy
Humans ; Lung ; Vital Capacity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis.
Autorzy:
Shi X; Department of Dermatology, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P. R. China.
Chen Y; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.
Liu Q; Department of Dermatology, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P. R. China.
Mei X; Department of Dermatology, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P. R. China.
Liu J; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.; Division of Rheumatology, Huashan hospital, Fudan University, Shanghai, P. R. China.
Tang Y; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.
Luo R; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.
Sun D; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.
Ma Y; MOE Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, P. R. China.; Institute for Six-sector Economy, Fudan University, Shanghai, P. R. China.
Wu W; Department of Dermatology, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P. R. China.
Tu W; Division of Rheumatology, Shanghai TCM-Integrated Hospital, Shanghai, P. R. China.
Zhao Y; Division of Rheumatology, Shanghai TCM-Integrated Hospital, Shanghai, P. R. China.
Xu W; The Clinical Laboratory of Tongren Hosipital, Shanghai Jiaotong University, Shanghai, P. R. China.
Ke Y; Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, P. R. China.
Jiang S; Department of Dermatology, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P. R. China.; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.
Huang Y; Department of Dermatology, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P. R. China.
Zhang R; Department of Dermatology, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P. R. China.; Institute for Six-sector Economy, Fudan University, Shanghai, P. R. China.
Wang L; Division of Rheumatology, Shanghai TCM-Integrated Hospital, Shanghai, P. R. China.
Chen Y; Division of Rheumatology, Shanghai TCM-Integrated Hospital, Shanghai, P. R. China.
Xia J; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.
Pu W; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.
Zhu H; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen, Nuremberg, Germany.; Department of Rheumatology, Xiangya Hospital, Central South University, Changsha, Hunan Province, P. R. China.
Zuo X; Department of Rheumatology, Xiangya Hospital, Central South University, Changsha, Hunan Province, P. R. China.
Li Y; Department of Rheumatology, Xiangya Hospital, Central South University, Changsha, Hunan Province, P. R. China.
Xu J; Department of Dermatology, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P. R. China.
Gao F; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, P. R. China.
Wei D; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, P. R. China.
Chen J; Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, P. R. China.
Yin W; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, P. R. China.
Wang Q; Rheumatology and Immunology Department, Peking University Shenzhen Hospital, Shenzhen, P. R. China.
Dai H; Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital; National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Science, Beijing, P. R. China.
Yang L; Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital; National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Science, Beijing, P. R. China.; School of Medicine, Tsinghua University, Beijing, P. R. China.
Guo G; Department of Rheumatology and Immunology, Yiling Hospital Affiliated to Hebei Medical University, Shijiazhuang, Hebei Province, P. R. China.
Cui J; Department of Rheumatology and Immunology, Yiling Hospital Affiliated to Hebei Medical University, Shijiazhuang, Hebei Province, P. R. China.
Song N; Department of Nephrology, Zhongshan Hospital, Fudan University, Fudan Zhangjiang Institute, Shanghai, P. R. China.
Zou H; Division of Rheumatology, Huashan hospital, Fudan University, Shanghai, P. R. China.; Institute of Rheumatology, Immunology and Allergy, Fudan University, Shanghai, P. R. China.
Zhao S; Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, P. R. China.
Distler JHW; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen, Nuremberg, Germany.
Jin L; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.; Research Unit of Dissecting the Population Genetics and Developing New Technologies for Treatment and Prevention of Skin Phenotypes and Dermatological Diseases (2019RU058), Chinese Academy of Medical Sciences, Shanghai, P. R. China.
Wang J; Department of Dermatology, Huashan Hospital and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P. R. China.; Human Phenome Institute and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai, P. R. China.; Institute of Rheumatology, Immunology and Allergy, Fudan University, Shanghai, P. R. China.; Research Unit of Dissecting the Population Genetics and Developing New Technologies for Treatment and Prevention of Skin Phenotypes and Dermatological Diseases (2019RU058), Chinese Academy of Medical Sciences, Shanghai, P. R. China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Jan; Vol. 12 (1), pp. e711.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lipoproteins, LDL/*genetics
Pulmonary Fibrosis/*etiology
Receptors, LDL/*metabolism
Animals ; Disease Models, Animal ; Lipoproteins, LDL/drug effects ; Mice ; Mice, Inbred C57BL/genetics ; Mice, Inbred C57BL/metabolism ; Pulmonary Fibrosis/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study.
Autorzy:
Štorkánová H; Institute of Rheumatology, Prague, Czech Republic.; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Oreská S; Institute of Rheumatology, Prague, Czech Republic.; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Špiritović M; Institute of Rheumatology, Prague, Czech Republic.; Department of Physiotherapy, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic.
Heřmánková B; Department of Physiotherapy, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic.
Bubová K; Institute of Rheumatology, Prague, Czech Republic.; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Komarc M; Department of Methodology, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic.
Pavelka K; Institute of Rheumatology, Prague, Czech Republic.; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Vencovský J; Institute of Rheumatology, Prague, Czech Republic.; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Distler JHW; Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
Šenolt L; Institute of Rheumatology, Prague, Czech Republic.; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Bečvář R; Institute of Rheumatology, Prague, Czech Republic.; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Tomčík M; Institute of Rheumatology, Prague, Czech Republic. .; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jan 07; Vol. 11 (1), pp. 1. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HSP90 Heat-Shock Proteins/*blood
Lung Diseases, Interstitial/*blood
Scleroderma, Systemic/*blood
Adult ; Aged ; C-Reactive Protein/metabolism ; Carbon Monoxide/metabolism ; Case-Control Studies ; Cross-Sectional Studies ; Cyclophosphamide/therapeutic use ; Dermatitis/metabolism ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Longitudinal Studies ; Lung/physiopathology ; Lung Diseases, Interstitial/drug therapy ; Lung Diseases, Interstitial/etiology ; Male ; Middle Aged ; Prospective Studies ; Pulmonary Diffusing Capacity/drug effects ; Scleroderma, Systemic/complications ; Scleroderma, Systemic/drug therapy ; Skin/physiopathology ; Vital Capacity/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cellular and molecular mechanisms in fibrosis.
Autorzy:
Dees C; Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Department of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany.
Chakraborty D; Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Department of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany.
Distler JHW; Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Department of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany.
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Źródło:
Experimental dermatology [Exp Dermatol] 2021 Jan; Vol. 30 (1), pp. 121-131. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Signal Transduction*
Fibrosis/*metabolism
Idiopathic Pulmonary Fibrosis/*metabolism
Scleroderma, Systemic/*metabolism
Skin/*pathology
Transforming Growth Factor beta/*metabolism
Animals ; DNA Methylation ; Ephrins/metabolism ; Fibroblast Growth Factor 9/metabolism ; Fibrosis/genetics ; Fibrosis/pathology ; Guanylate Cyclase/metabolism ; Histone Code ; Humans ; Idiopathic Pulmonary Fibrosis/genetics ; Idiopathic Pulmonary Fibrosis/pathology ; Janus Kinases/metabolism ; Myofibroblasts ; Receptors, Cytoplasmic and Nuclear/metabolism ; STAT Transcription Factors/metabolism ; Scleroderma, Systemic/genetics ; Scleroderma, Systemic/pathology ; Serotonin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Translational engagement of lysophosphatidic acid receptor 1 in skin fibrosis: from dermal fibroblasts of patients with scleroderma to tight skin 1 mouse.
Autorzy:
Ledein L; Cardiovascular & Metabolism Unit, Sanofi, Chilly-Mazarin, France.
Léger B; Cardiovascular & Metabolism Unit, Sanofi, Chilly-Mazarin, France.
Dees C; Department of Internal Medicine 3, Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
Beyer C; Department of Internal Medicine 3, Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
Distler A; Department of Internal Medicine 3, Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
Vettori S; Department of Clinical and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy.
Boukaiba R; IDD Department, Sanofi, Vitry-sur-Seine, France.
Bidouard JP; Cardiovascular & Metabolism Unit, Sanofi, Chilly-Mazarin, France.
Schaefer M; R&D Diabetes Division, Sanofi, Frankfurt, Germany.
Pernerstorfer J; R&D Diabetes Division, Sanofi, Frankfurt, Germany.
Ruetten H; R&D Diabetes Division, Sanofi, Frankfurt, Germany.
Jagerschmidt A; Cardiovascular & Metabolism Unit, Sanofi, Chilly-Mazarin, France.
Janiak P; Cardiovascular & Metabolism Unit, Sanofi, Chilly-Mazarin, France.
Distler JHW; Department of Internal Medicine 3, Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
Distler O; Department of Rheumatology, University Hospital Zurich, Zürich, Switzerland.
Illiano S; Cardiovascular & Metabolism Unit, Sanofi, Chilly-Mazarin, France.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2020 Sep; Vol. 177 (18), pp. 4296-4309. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Lysophosphatidic Acid*
Scleroderma, Systemic*/drug therapy
Scleroderma, Systemic*/pathology
Animals ; Disease Models, Animal ; Fibroblasts/pathology ; Fibrosis ; Humans ; Mice ; Skin/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
GBA1 as a risk gene for osteoporosis in the specific populations and its role in the development of Gaucher disease.
Autorzy:
Wang, Chung-Hsing (AUTHOR)
Huang, Yu‐Nan (AUTHOR)
Liao, Wen-Ling (AUTHOR)
Hsieh, Ai-Ru (AUTHOR)
Lin, Wei-De (AUTHOR)
Liu, Kai-Wen (AUTHOR)
Lu, Wen-Li (AUTHOR)
Huang, Chieh‐Chen (AUTHOR)
Chien, Yin-Hsiu (AUTHOR)
Lee, Ni-Chung (AUTHOR)
Su, Pen-Hua (AUTHOR)
Tsai, Fuu-Jen (AUTHOR)
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Źródło:
Orphanet Journal of Rare Diseases. 4/4/2024, Vol. 19 Issue 1, p1-16. 16p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The occurrence and development mechanisms of esophageal stricture: state of the art review.
Autorzy:
Yang, Fang (AUTHOR)
Hu, Yiwei (AUTHOR)
Shi, Zewen (AUTHOR)
Liu, Mujie (AUTHOR)
Hu, Kefeng (AUTHOR)
Ye, Guoliang (AUTHOR)
Pang, Qian (AUTHOR)
Hou, Ruixia (AUTHOR)
Tang, Keqi (AUTHOR)
Zhu, Yabin (AUTHOR)
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Źródło:
Journal of Translational Medicine. 1/31/2024, Vol. 22, p1-14. 14p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Neutrophil extracellular traps mediated by platelet microvesicles promote thrombosis and brain injury in acute ischemic stroke.
Autorzy:
Gao, Xin (AUTHOR)
Zhao, Xinyi (AUTHOR)
Li, Jiacheng (AUTHOR)
Liu, Chang (AUTHOR)
Li, Wenqiang (AUTHOR)
Zhao, Junjie (AUTHOR)
Li, Zhixi (AUTHOR)
Wang, Nan (AUTHOR)
Wang, Fang (AUTHOR)
Dong, Jiawei (AUTHOR)
Yan, Xiuwei (AUTHOR)
Zhang, Jiheng (AUTHOR)
Hu, Xueyan (AUTHOR)
Jin, Jiaqi (AUTHOR)
Mang, Ge (AUTHOR)
Ma, Ruishuang (AUTHOR)
Hu, Shaoshan (AUTHOR)
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Źródło:
Cell Communication & Signaling. 1/17/2024, Vol. 22 Issue 1, p1-12. 12p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exosome-based engineering strategies for the diagnosis and treatment of oral and maxillofacial diseases.
Autorzy:
Ren, Jianing (AUTHOR)
Jing, Xuan (AUTHOR)
Liu, Yingyu (AUTHOR)
Liu, Jinrong (AUTHOR)
Ning, Xiao (AUTHOR)
Zong, Mingrui (AUTHOR)
Zhang, Ran (AUTHOR)
Cheng, Huaiyi (AUTHOR)
Cui, Jiayu (AUTHOR)
Li, Bing (AUTHOR)
Wu, Xiuping (AUTHOR)
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Źródło:
Journal of Nanobiotechnology. 12/21/2023, Vol. 21 Issue 1, p1-18. 18p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Extracellular matrix analysis of fibrosis: A step towards tissue engineering for urethral stricture disease.
Autorzy:
Linssen, Emma C. (AUTHOR)
Demmers, Jeroen (AUTHOR)
van Dijk, Christian G. M. (AUTHOR)
van Dam, Roos (AUTHOR)
Nicese, Maria Novella (AUTHOR)
Cheng, Caroline (AUTHOR)
de Kort, Laetitia M. O. (AUTHOR)
de Graaf, Petra (AUTHOR)
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Źródło:
PLoS ONE. 11/30/2023, Vol. 18 Issue 11, p1-16. 16p.
Czasopismo naukowe
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Tytuł:
Cutaneous wound healing promoted by topical administration of heat-killed Lactobacillus plantarum KB131 and possible contribution of CARD9-mediated signaling.
Autorzy:
Ishi, Shinyo (AUTHOR)
Kanno, Emi (AUTHOR)
Tanno, Hiromasa (AUTHOR)
Kurosaka, Shiho (AUTHOR)
Shoji, Miki (AUTHOR)
Imai, Toshiro (AUTHOR)
Yamaguchi, Kenji (AUTHOR)
Kotsugai, Kanna (AUTHOR)
Niiyama, Momoko (AUTHOR)
Kurachi, Haruko (AUTHOR)
Makabe, Fuko (AUTHOR)
Watanabe, Takumi (AUTHOR)
Sato, Ko (AUTHOR)
Ishii, Keiko (AUTHOR)
Hara, Hiromitsu (AUTHOR)
Imai, Yoshimichi (AUTHOR)
Kawakami, Kazuyoshi (AUTHOR)
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Źródło:
Scientific Reports. 11/18/2023, Vol. 13 Issue 1, p1-12. 12p.
Czasopismo naukowe
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Wyświetlanie 1-20 z 936

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