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Wyszukujesz frazę ""Hydroxyurea"" wg kryterium: Wszystkie pola

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Wyświetlanie 1-20 z 59311
Tytuł:
Role of hydroxyurea therapy in the prevention of organ damage in sickle cell disease: a systematic review and meta-analysis.
Autorzy:
Khargekar N; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India. .
Banerjee A; Department of Transfusion Transmitted Disease, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India.
Athalye S; Department of Transfusion Transmitted Disease, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India.
Mahajan N; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India.
Kargutkar N; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India.
Tapase P; Department of Paediatric Immunology & Leukocyte Biology, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Parel, Mumbai, 400 012, India.
Madkaikar M; Department of Paediatric Immunology & Leukocyte Biology, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Parel, Mumbai, 400 012, India.
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Źródło:
Systematic reviews [Syst Rev] 2024 Feb 08; Vol. 13 (1), pp. 60. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
Hydroxyurea*/therapeutic use
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/drug therapy
Humans ; Antisickling Agents/therapeutic use ; Albuminuria/drug therapy ; Blood Transfusion
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genome instability footprint under rapamycin and hydroxyurea treatments.
Autorzy:
Li J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.; Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice, France.
Stenberg S; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Yue JX; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.; Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice, France.
Mikhalev E; Ginkgo Bioworks, Boston, Massachusetts, United States of America.
Thompson D; Ginkgo Bioworks, Boston, Massachusetts, United States of America.
Warringer J; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Liti G; Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice, France.
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Źródło:
PLoS genetics [PLoS Genet] 2023 Nov 06; Vol. 19 (11), pp. e1011012. Date of Electronic Publication: 2023 Nov 06 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Hydroxyurea*/pharmacology
Saccharomyces cerevisiae*/genetics
Humans ; Sirolimus/pharmacology ; Mutation ; Genomic Instability/genetics ; DNA, Ribosomal/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hydroxyurea does not reverse functional alterations of the nitric oxide-cGMP pathway associated with priapism phenotype in corpus cavernosum from sickle cell mouse.
Autorzy:
Pereira, Dalila Andrade (AUTHOR)
Pereira, Danillo Andrade (AUTHOR)
da Silva Pereira, Pamela (AUTHOR)
Silveira, Tammyris Helena Rebecchi (AUTHOR)
Calmasini, Fabiano Beraldi (AUTHOR)
Reis, Leonardo Oliveira (AUTHOR)
Costa, Fernando Ferreira (AUTHOR)
Silva, Fábio Henrique (AUTHOR)
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Źródło:
PLoS ONE. 10/9/2023, Vol. 18 Issue 10, p1-11. 11p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Resumption of Spermatogenesis and Fertility Post Withdrawal of Hydroxyurea Treatment.
Autorzy:
Virgous C; Animal Care Facility, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37209, USA.
Lyons L; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Sakwe A; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Nayyar T; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Goodwin S; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Hildreth J; Department of Microbiology, Immunology and Physiology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Osteen K; Women's Reproductive Health Research Center, Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Bruner-Tran K; Women's Reproductive Health Research Center, Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Alawode O; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Bourne P; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Hills ER; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Archibong AE; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.; Department of Microbiology, Immunology and Physiology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 27; Vol. 24 (11). Date of Electronic Publication: 2023 May 27.
Typ publikacji:
Journal Article
MeSH Terms:
Hydroxyurea*/adverse effects
Hydroxyurea*/metabolism
Hypogonadism*/drug therapy
Hypogonadism*/metabolism
Female ; Male ; Mice ; Animals ; Sperm Motility ; Semen ; Spermatogenesis ; Testis/metabolism ; Fertility
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Are Genetic Modifiers the Answer to Different Responses to Hydroxyurea Treatment?-A Pharmacogenetic Study in Sickle Cell Anemia Angolan Children.
Autorzy:
Ginete C; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.
Delgadinho M; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.
Santos B; Centro de Investigação em Saúde de Angola (CISA), Bengo, Angola.; Hospital Pediátrico David Bernardino (HPDB), Luanda, Angola.
Pinto V; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.; Centro de Estatística e Aplicações, Universidade de Lisboa (CEAUL), 1749-016 Lisbon, Portugal.
Silva C; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.; Centro de Estatística e Aplicações, Universidade de Lisboa (CEAUL), 1749-016 Lisbon, Portugal.
Miranda A; Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA), 1649-016 Lisbon, Portugal.
Brito M; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.; Centro de Investigação em Saúde de Angola (CISA), Bengo, Angola.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 15; Vol. 24 (10). Date of Electronic Publication: 2023 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Hydroxyurea*/adverse effects
Anemia, Sickle Cell*/drug therapy
Anemia, Sickle Cell*/genetics
Anemia, Sickle Cell*/complications
Humans ; Pharmacogenomic Testing ; Hemolysis ; Fetal Hemoglobin/analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Leveraging mathematical modeling to analyze nonadherence for hydroxyurea therapy in sickle cell disease.
Autorzy:
Pandey A; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana, USA.
Raja R; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana, USA.
Estepp JH; Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Agios Pharmaceuticals, Cambridge, Massachusetts, USA.
Ramkrishna D; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana, USA.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Jun; Vol. 12 (6), pp. 748-757. Date of Electronic Publication: 2023 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
Hydroxyurea*/therapeutic use
Anemia, Sickle Cell*/drug therapy
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Real-World Clinical Characterisation of Polycythaemia Vera Patients from a Prospective Registry in Portugal: Is Resistance to Hydroxyurea a Reality?
Autorzy:
Sarmento, Maria
Duarte, Marta
Ponte, Sandra
Sanchez, Juan
Roriz, Diana
Fernandes, Laura
Monteiro Silva, Maria José
Pacheco, Judite
Ferreira, Gisela
Freitas, Jorge
Costa, Inês
Brás, Daniel
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Źródło:
Hematology Reports. Sep2023, Vol. 15 Issue 3, p532-542. 11p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Predictors of Response to Hydroxyurea and Switch to Ruxolitinib in HU-Resistant Polycythaemia VERA Patients: A Real-World PV-NET Study.
Autorzy:
Palandri, Francesca (AUTHOR)
Rossi, Elena (AUTHOR)
Auteri, Giuseppe (AUTHOR)
Breccia, Massimo (AUTHOR)
Paglia, Simona (AUTHOR)
Benevolo, Giulia (AUTHOR)
Elli, Elena M. (AUTHOR)
Cavazzini, Francesco (AUTHOR)
Binotto, Gianni (AUTHOR)
Tieghi, Alessia (AUTHOR)
Tiribelli, Mario (AUTHOR)
Heidel, Florian H. (AUTHOR)
Bonifacio, Massimiliano (AUTHOR)
Pugliese, Novella (AUTHOR)
Caocci, Giovanni (AUTHOR)
Crugnola, Monica (AUTHOR)
Mendicino, Francesco (AUTHOR)
D'Addio, Alessandra (AUTHOR)
Tomassetti, Simona (AUTHOR)
Martino, Bruno (AUTHOR)
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Źródło:
Cancers. Jul2023, Vol. 15 Issue 14, p3706. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Outcomes of Hydroxyurea Accessed via Various Means and Barriers Affecting Its Usage Among Children with Sickle Cell Anaemia in North-Western Tanzania.
Autorzy:
Ambrose, Emmanuela E (AUTHOR)
Kidenya, Benson R (AUTHOR)
Charles, Mwesige (AUTHOR)
Ndunguru, Joyce (AUTHOR)
Jonathan, Agnes (AUTHOR)
Makani, Julie (AUTHOR)
Minja, Irene K (AUTHOR)
Ruggajo, Paschal (AUTHOR)
Balandya, Emmanuel (AUTHOR)
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Źródło:
Journal of Blood Medicine. Jan2023, Vol. 14, p37-47. 11p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Utilization of Hydroxyurea Among Patients Diagnosed with Sickle Cell Disease in Jazan, Saudi Arabia.
Autorzy:
Gohal, Gassem A (AUTHOR)
Gosadi, Ibrahim M (AUTHOR)
Iqbal, Basheer Ahmed Cittana (AUTHOR)
Ghazwani, Yahya H (AUTHOR)
Daghriri, Amal M (AUTHOR)
Shugairi, Ahmad A (AUTHOR)
Daghriri, Khaled A (AUTHOR)
Zurayyir, Atyaf J (AUTHOR)
Nemri, Abdulrhman A (AUTHOR)
Abdulhaq, Monera A (AUTHOR)
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Źródło:
Patient Preference & Adherence. Nov2022, Vol. 16, p3059-3067. 9p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prognostic value of modified criteria for hydroxyurea resistance or intolerance in patients with high-risk essential thrombocythemia.
Autorzy:
Park YH; Division of Hematology-Oncology, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Lee S; Division of Hematology-Oncology, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Mun YC; Division of Hematology-Oncology, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Park DJ; Department of Laboratory Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
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Źródło:
Cancer medicine [Cancer Med] 2023 Apr; Vol. 12 (7), pp. 8073-8082. Date of Electronic Publication: 2023 Jan 09.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Hydroxyurea*/adverse effects
Thrombocythemia, Essential*/diagnosis
Thrombocythemia, Essential*/drug therapy
Adult ; Aged ; Aged, 80 and over ; Humans ; Middle Aged ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cost-Effectiveness of Hydroxyurea for Sickle Cell Anemia in a Low-Income African Setting: A Model-Based Evaluation of Two Dosing Regimens.
Autorzy:
Teigen, David (AUTHOR)
Opoka, Robert O. (AUTHOR)
Kasirye, Phillip (AUTHOR)
Nabaggala, Catherine (AUTHOR)
Hume, Heather A. (AUTHOR)
Blomberg, Bjørn (AUTHOR)
John, Chandy C. (AUTHOR)
Ware, Russell E. (AUTHOR)
Robberstad, Bjarne (AUTHOR)
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Źródło:
PharmacoEconomics. Dec2023, Vol. 41 Issue 12, p1603-1615. 13p.
Czasopismo naukowe
Szczegóły
Tytuł:
Advanced clinical parameters: A complementary hydroxyurea adherence evaluation in sickle cell anemia treatment.
Autorzy:
Moreira ID; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Lessa CLM; Graduate Program in Pathology, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Rocha GLG; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.; Clinicas Hospital of Porto Alegre/RS, Porto Alegre/RS, Brazil.
Schmitz LD; Undergraduate Program in Pharmacy, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Jahnke VS; Vale do Rio dos Sinos University (UNISINOS), Porto Alegre/RS, Brazil.
Fogliatto LM; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.; Graduate Program in Pathology, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Werlang MC; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Rotta LN; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
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Źródło:
European journal of haematology [Eur J Haematol] 2022 Dec; Vol. 109 (6), pp. 736-748. Date of Electronic Publication: 2022 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Hydroxyurea*/therapeutic use
Anemia, Sickle Cell*/diagnosis
Anemia, Sickle Cell*/drug therapy
Child ; Adult ; Adolescent ; Humans ; Antisickling Agents/therapeutic use ; Cross-Sectional Studies ; Blood Cell Count
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ten-year longitudinal analysis of hydroxyurea implementation in a pediatric sickle cell program.
Autorzy:
Phan V; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Park JA; Inova Fairfax Hospital, Falls Church, Virginia, USA.
Dulman R; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Lewis A; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Briere N; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Notarangelo B; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Yang E; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.; Department of Pediatrics, George Washington University School of Medicine, Washington, District of Columbia, USA.
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Źródło:
European journal of haematology [Eur J Haematol] 2022 Nov; Vol. 109 (5), pp. 465-473. Date of Electronic Publication: 2022 Sep 02.
Typ publikacji:
Journal Article
MeSH Terms:
Anemia, Sickle Cell*/diagnosis
Anemia, Sickle Cell*/drug therapy
Anemia, Sickle Cell*/epidemiology
Hydroxyurea*/therapeutic use
Antisickling Agents/therapeutic use ; Blood Transfusion ; Child ; Erythrocytes, Abnormal ; Fetal Hemoglobin ; Humans ; Infant
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The impact of Hydroxyurea on the rates of Vaso-occlusive crises in patients with sickle cell disease in Saudi Arabia: a single-center study.
Autorzy:
Alkhalifah SA; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Alanazi M; Department of Pharmacy, King Khalid University Hospital, P.O. Box 3145, Riyadh, 12372, Saudi Arabia.
Almasaoud MA; College of Medicine, King Saud University, Riyadh, 11451, Saudi Arabia.
Al-Malki HS; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Al-Murdhi FM; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Al-Hazzaa MS; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Al-Mufarrij SM; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Albabtain MA; College of Medicine, King Saud University, Riyadh, 11451, Saudi Arabia.
Alshiakh AA; College of Medicine, King Saud University, Riyadh, 11451, Saudi Arabia.
AlRuthia Y; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia. .; Pharmacoeconomics Research Unit, Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia. .
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Źródło:
BMC emergency medicine [BMC Emerg Med] 2022 Nov 29; Vol. 22 (1), pp. 188. Date of Electronic Publication: 2022 Nov 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hydroxyurea*/therapeutic use
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/drug therapy
Female ; Humans ; Male ; Child ; Saudi Arabia/epidemiology ; Retrospective Studies ; Cognition
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Disseminated superficial actinic porokeratosis following hydroxyurea treatment: A case report.
Autorzy:
Romagnuolo, Maurizio (AUTHOR)
Riva, Davide (AUTHOR)
Alberti Violetti, Silvia (AUTHOR)
Di Benedetto, Alessandra (AUTHOR)
Barberi, Francesco (AUTHOR)
Moltrasio, Chiara (AUTHOR)
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Źródło:
Australasian Journal of Dermatology. Feb2023, Vol. 64 Issue 1, pe72-e75. 4p. 2 Color Photographs.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 59311

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