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Wyświetlanie 1-20 z 7004
Tytuł:
Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease.
Autorzy:
Hafez DE; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
Dubiel M; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf, Germany.
La Spada G; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Bari, Italy.
Catto M; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, Bari, Italy.
Reiner-Link D; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf, Germany.
Syu YT; Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Abdel-Halim M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
Hwang TL; Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Research Center for Chinese Herbal Medicine, Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan, Taiwan.; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.; Department of Chemical Engineering, Ming Chi University of Technology, New Taipei City, Taiwan.
Stark H; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf, Germany.
Abadi AH; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2175821.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Humans ; Structure-Activity Relationship ; Cholinesterase Inhibitors/pharmacology ; Cholinesterase Inhibitors/chemistry ; Acetylcholinesterase/metabolism ; Monoamine Oxidase/metabolism ; Monoamine Oxidase Inhibitors/pharmacology ; Monoamine Oxidase Inhibitors/chemistry ; Benzothiazoles/pharmacology ; Ligands
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Digital Color Stimulator for Vision Research
Autorzy:
Link, D.
Klee, S.
Seifert, B. U.
Haueisen, J.
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Źródło:
World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany : Vol. 25/11 Biomedical Engineering for Audiology, Ophthalmology, Emergency & Dental Medicine. 25/11:231-234
Książka elektroniczna
Szczegóły
Tytuł:
Fundus Controlled Silent Substitution Stimulation of the Human Eye
Autorzy:
Klee, S.
Link, D.
Bessler, P.
Haueisen, J.
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Źródło:
World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany : Vol. 25/11 Biomedical Engineering for Audiology, Ophthalmology, Emergency & Dental Medicine. 25/11:219-222
Książka elektroniczna
Szczegóły
Tytuł:
Benzophenone Derivatives with Histamine H 3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.
Autorzy:
Godyń J; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Zaręba P; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Stary D; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.; Doctoral School of Medical and Health Sciences, Jagiellonian University Medical College, św. Łazarza 16 St., 31-530 Krakow, Poland.
Kaleta M; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Kuder KJ; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Latacz G; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Mogilski S; Department of Pharmacodynamics, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Reiner-Link D; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Duesseldorf, Universitaetsstr. 1, 40225 Duesseldorf, Germany.
Frank A; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Duesseldorf, Universitaetsstr. 1, 40225 Duesseldorf, Germany.
Doroz-Płonka A; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Olejarz-Maciej A; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Sudoł-Tałaj S; Doctoral School of Medical and Health Sciences, Jagiellonian University Medical College, św. Łazarza 16 St., 31-530 Krakow, Poland.; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Nolte T; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Handzlik J; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Stark H; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Duesseldorf, Universitaetsstr. 1, 40225 Duesseldorf, Germany.
Więckowska A; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Malawska B; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Kieć-Kononowicz K; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Łażewska D; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
Bajda M; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9 St., 30-688 Krakow, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 28; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Receptors, Histamine H3*/metabolism
Mice ; Animals ; Cholinesterases/metabolism ; Histamine ; Cholinesterase Inhibitors/pharmacology ; Receptors, Histamine ; Ligands ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clonal diversity of recurrently mutated genes in myelodysplastic syndromes
Autorzy:
Walter, M JAff1, Aff2, Aff3
Shen, D
Shao, J
Ding, LAff1, Aff2, Aff3, Aff4
White, B SAff1, Aff4
Kandoth, C
Miller, C A
Niu, B
McLellan, M D
Dees, N D
Fulton, R
Elliot, K
Heath, S
Grillot, M
Westervelt, PAff1, Aff3
Link, D CAff1, Aff3
DiPersio, J FAff1, Aff3
Mardis, EAff2, Aff4
Ley, T JAff1, Aff2, Aff3, Aff4
Wilson, R KAff2, Aff3, Aff4, Aff5
Graubert, T AAff1, Aff3, Aff6, IDleu201358_cor21
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Źródło:
Leukemia. 27(6):1275-1282
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Dual Targeting Ligands-Histamine H 3 Receptor Ligands with Monoamine Oxidase B Inhibitory Activity-In Vitro and In Vivo Evaluation.
Autorzy:
Łażewska D; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College in Kraków, Medyczna 9 Str., 30-688 Kraków, Poland.
Siwek A; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University Medical College in Kraków, Medyczna 9 Str, 30-688 Kraków, Poland.
Olejarz-Maciej A; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College in Kraków, Medyczna 9 Str., 30-688 Kraków, Poland.
Doroz-Płonka A; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College in Kraków, Medyczna 9 Str., 30-688 Kraków, Poland.
Wiktorowska-Owczarek A; Department of Pharmacology and Toxicology, Medical University of Lodz, Żeligowskiego 7/9 Str., 90-752 Łódź, Poland.
Jóźwiak-Bębenista M; Department of Pharmacology and Toxicology, Medical University of Lodz, Żeligowskiego 7/9 Str., 90-752 Łódź, Poland.
Reiner-Link D; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitaetsstr. 1, 40225 Düsseldorf, Germany.
Frank A; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitaetsstr. 1, 40225 Düsseldorf, Germany.
Sromek-Trzaskowska W; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College in Kraków, Medyczna 9 Str., 30-688 Kraków, Poland.
Honkisz-Orzechowska E; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College in Kraków, Medyczna 9 Str., 30-688 Kraków, Poland.
Królicka E; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College in Kraków, Medyczna 9 Str., 30-688 Kraków, Poland.
Stark H; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitaetsstr. 1, 40225 Düsseldorf, Germany.
Wieczorek M; Department of Neurobiology, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143 Str., 90-236 Łódź, Poland.
Wagner W; Department of Hormone Biochemistry, Medical University of Lodz, Żeligowskiego 7/9 Str., 90-752 Łódź, Poland.; Laboratory of Cellular Immunology, Institute of Medical Biology of Polish Academy of Sciences, 106 Lodowa Str., 93-232 Łódź, Poland.
Kieć-Kononowicz K; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College in Kraków, Medyczna 9 Str., 30-688 Kraków, Poland.
Stasiak A; Department of Hormone Biochemistry, Medical University of Lodz, Żeligowskiego 7/9 Str., 90-752 Łódź, Poland.
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Źródło:
Pharmaceutics [Pharmaceutics] 2022 Oct 13; Vol. 14 (10). Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Predicting the in-game status in soccer with machine learning using spatiotemporal player tracking data.
Autorzy:
Lang S; Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany. .
Wild R; Department of Informatics, Technical University of Munich, Munich, Germany.
Isenko A; Department of Informatics, Technical University of Munich, Munich, Germany.
Link D; Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany.; Munich Data Science Institute (MDSI), Technical University of Munich, Garching, Germany.
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Źródło:
Scientific reports [Sci Rep] 2022 Sep 29; Vol. 12 (1), pp. 16291. Date of Electronic Publication: 2022 Sep 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Household Articles*
Soccer*
Adolescent ; Athletes ; Humans ; Machine Learning ; Reading Frames
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 7004

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