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Tytuł:
Detection of a historic reservoir of bedaquiline/clofazimine resistance-associated variants in Mycobacterium tuberculosis.
Autorzy:
Nimmo C; UCL Genetics Institute, University College London, Darwin Building, Gower Street, London, UK. .; Division of Infection and Immunity, University College London, London, UK. .; Africa Health Research Institute, Durban, South Africa. .
Ortiz AT; UCL Genetics Institute, University College London, Darwin Building, Gower Street, London, UK.; Department of Medicine, Imperial College, London, UK.
Tan CCS; UCL Genetics Institute, University College London, Darwin Building, Gower Street, London, UK.
Pang J; UCL Genetics Institute, University College London, Darwin Building, Gower Street, London, UK.; Division of Infection and Immunity, University College London, London, UK.
Acman M; UCL Genetics Institute, University College London, Darwin Building, Gower Street, London, UK.
Millard J; Africa Health Research Institute, Durban, South Africa.; Wellcome Trust Liverpool Glasgow Centre for Global Health Research, Liverpool, UK.; Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.
Padayatchi N; CAPRISA MRC-HIV-TB Pathogenesis and Treatment Research Unit, Durban, South Africa.
Grant AD; Africa Health Research Institute, Durban, South Africa.; TB Centre, London School of Hygiene & Tropical Medicine, London, UK.
O'Donnell M; CAPRISA MRC-HIV-TB Pathogenesis and Treatment Research Unit, Durban, South Africa.; Department of Medicine & Epidemiology, Columbia University Irving Medical Center, New York, NY, USA.
Pym A; Africa Health Research Institute, Durban, South Africa.
Brynildsrud OB; Division of Infectious Diseases and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Eldholm V; Division of Infectious Diseases and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Grandjean L; Division of Infection and Immunity, University College London, London, UK.; Laboratorio de Investigacion y Enfermedades Infecciosas, Universidad Peruana Cayetano Heredia, Lima, Peru.; Department of Infection, Immunity and Inflammation, Institute of Child Health, University College London, London, UK.
Didelot X; School of Life Sciences and Department of Statistics, University of Warwick, Coventry, UK.
Balloux F; UCL Genetics Institute, University College London, Darwin Building, Gower Street, London, UK. .
van Dorp L; UCL Genetics Institute, University College London, Darwin Building, Gower Street, London, UK. .
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Źródło:
Genome medicine [Genome Med] 2024 Feb 19; Vol. 16 (1), pp. 34. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*/genetics
Tuberculosis*/drug therapy
Diarylquinolines*
Humans ; Clofazimine ; Antitubercular Agents/pharmacology ; Antitubercular Agents/therapeutic use ; Microbial Sensitivity Tests ; Phylogeny
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integrated Analysis of Single-Cell and Bulk RNA Sequencing Data Reveals Memory-like NK Cell Subset Associated with Mycobacterium tuberculosis Latency.
Autorzy:
Shekarkar Azgomi M; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Biomedicine, Neurosciences and Advanced Diagnostic (BND), University of Palermo, 90127 Palermo, Italy.
Badami GD; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.
Lo Pizzo M; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.
Tamburini B; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Health Promotion, Mother and Childcare, Internal Medicine and Medical Specialties, University of Palermo, 90129 Palermo, Italy.
Dieli C; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.
La Manna MP; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Biomedicine, Neurosciences and Advanced Diagnostic (BND), University of Palermo, 90127 Palermo, Italy.
Dieli F; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Biomedicine, Neurosciences and Advanced Diagnostic (BND), University of Palermo, 90127 Palermo, Italy.
Caccamo N; Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico (AOUP) Paolo Giaccone, University of Palermo, 90127 Palermo, Italy.; Department of Biomedicine, Neurosciences and Advanced Diagnostic (BND), University of Palermo, 90127 Palermo, Italy.
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Źródło:
Cells [Cells] 2024 Feb 06; Vol. 13 (4). Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Tuberculosis*
Humans ; RNA ; Immunity, Innate ; Killer Cells, Natural ; Sequence Analysis, RNA ; NK Cell Lectin-Like Receptor Subfamily C
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mycobacterium tuberculosis sepsis with multiple intermuscular abscesses and respiratory failure as the main manifestations: a case report.
Autorzy:
Tang Y; Department of Infectious Diseases, First Affiliated Hospital, Army Medical University, Chongqing, China.
Zhu Y; Department of Infectious Diseases, First Affiliated Hospital, Army Medical University, Chongqing, China.
You Z; Department of Infectious Diseases, First Affiliated Hospital, Army Medical University, Chongqing, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Mar 21; Vol. 24 (1), pp. 340. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Mycobacterium tuberculosis*/genetics
Shock, Septic*
Sepsis*/diagnosis
Tuberculosis, Miliary*
Respiratory Insufficiency*
Humans ; Female ; Middle Aged ; Abscess/diagnosis ; High-Throughput Nucleotide Sequencing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of Novel Antimicrobial Compounds Targeting Mycobacterium tuberculosis S -Adenosyl-L-Homocysteine Hydrolase Using Dual Hierarchical In Silico Structure-Based Drug Screening.
Autorzy:
Ito H; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan.
Monobe K; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan.
Okubo S; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan.
Aoki S; Department of Bioscience and Bioinformatics, Graduate School of Computer Science and Systems Engineering, Kyushu Institute of Technology, Iizuka 820-8502, Japan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 14; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Tuberculosis*/microbiology
Humans ; Antitubercular Agents/chemistry ; Drug Evaluation, Preclinical ; Homocysteine/pharmacology ; Hydrolases/pharmacology ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Iron-related gene mutations driving global Mycobacterium tuberculosis transmission revealed by whole-genome sequencing.
Autorzy:
Li Y; Clinical Department of Integrated Traditional Chinese and Western Medicine , The First Clinical Medical College of Shandong University of Traditional Chinese Medicine, 250014, Jinan, Shandong, People's Republic of China.
Li Y; Department of Pulmonary and Critical Care Medicine, The Third Affiliated Hospital of Shandong First Medical University (Affiliated Hospital of Shandong Academy of Medical Sciences), 250031, Jinan, Shandong, People's Republic of China.
Liu Y; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250021, Jinan, Shandong, People's Republic of China.
Kong X; Artificial Intelligence Institute, Qilu University of Technology (Shandong Academy of Sciences), 250011, Jinan, Shandong, People's Republic of China.
Tao N; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250021, Jinan, Shandong, People's Republic of China.
Hou Y; Institute of Chinese Medical Literature and Culture of Shandong University of Traditional Chinese Medicine, 250355, Jinan, Shandong, People's Republic of China.
Wang T; Clinical Department of Integrated Traditional Chinese and Western Medicine , The First Clinical Medical College of Shandong University of Traditional Chinese Medicine, 250014, Jinan, Shandong, People's Republic of China.
Han Q; Shandong First Medical University & Shandong Academy of Medical Sciences, 250117, Jinan, Shandong, People's Republic of China.
Zhang Y; Shandong First Medical University & Shandong Academy of Medical Sciences, 250117, Jinan, Shandong, People's Republic of China.
Long F; Department of Pulmonary and Critical Care Medicine, The Third Affiliated Hospital of Shandong First Medical University (Affiliated Hospital of Shandong Academy of Medical Sciences), 250031, Jinan, Shandong, People's Republic of China. .
Li H; Clinical Department of Integrated Traditional Chinese and Western Medicine , The First Clinical Medical College of Shandong University of Traditional Chinese Medicine, 250014, Jinan, Shandong, People's Republic of China. .; Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250021, Jinan, Shandong, People's Republic of China. .
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Źródło:
BMC genomics [BMC Genomics] 2024 Mar 06; Vol. 25 (1), pp. 249. Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*/genetics
Tuberculosis*/genetics
Humans ; Whole Genome Sequencing ; Iron ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
circRNA_SLC8A1 promotes the survival of mycobacterium tuberculosis in macrophages by upregulating expression of autophagy-related protein SQSTM1/p62 to activate the NF-κB pathway.
Autorzy:
Li Z; Department of Tuberculosis, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, Henan, China.
Gao Y; Department of Tuberculosis, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, Henan, China.
Zhang B; Department of Tuberculosis, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, Henan, China.
Dong W; Department of Tuberculosis, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, Henan, China.
Xi Y; Clinical Pharmacy Office, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, Henan, China.
Li Y; Gastrointestinal Surgery, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, Henan, China.
Cui J; Department of Tuberculosis, The First Affiliated Hospital of Xinxiang Medical University, Weihui, 453100, Henan, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 04; Vol. 14 (1), pp. 5233. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
MicroRNAs*/genetics
Humans ; NF-kappa B ; Sequestosome-1 Protein/genetics ; RNA, Circular/genetics ; Autophagy-Related Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human Macrophages Activate Bystander Neutrophils' Metabolism and Effector Functions When Challenged with Mycobacterium tuberculosis .
Autorzy:
Murphy DM; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
Walsh A; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
Stein L; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
Petrasca A; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute (TBSI), Trinity College Dublin, The University of Dublin, D02 R590 Dublin, Ireland.
Cox DJ; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
Brown K; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
Duffin E; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
Jameson G; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
Connolly SA; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
O'Connell F; Department of Surgery, Trinity St. James's Cancer Institute, Trinity Translational Medicine Institute (TTMI), St. James's Hospital, Dublin 8, D08 W9RT Dublin, Ireland.
O'Sullivan J; Department of Surgery, Trinity St. James's Cancer Institute, Trinity Translational Medicine Institute (TTMI), St. James's Hospital, Dublin 8, D08 W9RT Dublin, Ireland.
Basdeo SA; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
Keane J; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
Phelan JJ; Department of Clinical Medicine, School of Medicine, Trinity Translational Medicine Institute (TTMI), Trinity Centre for Health Sciences, St. James's Hospital, Trinity College Dublin, The University of Dublin, Dublin 8, D08 W9RT Dublin, Ireland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 01; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Tuberculosis*
Pneumonia*/metabolism
Humans ; Neutrophils/metabolism ; Macrophages/metabolism ; Inflammation/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel mutation in efflux pump Rv1258c (Tap) gene in drug resistant clinical isolates of Mycobacterium tuberculosis in Iran.
Autorzy:
Farzaneh S; Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Norouzi F; Department of Microbiology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Fazeli H; Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Salehi M; Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Safari M; Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Nasr Esfahani B; Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
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Źródło:
Journal of infection in developing countries [J Infect Dev Ctries] 2024 Feb 29; Vol. 18 (2), pp. 243-250. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*/genetics
Tuberculosis, Multidrug-Resistant*
Humans ; Antitubercular Agents/pharmacology ; Iran ; Mutation ; Microbial Sensitivity Tests ; Bacterial Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Immune Dysregulation in SARS-CoV-2 patients coinfected with Mycobacterium tuberculosis (Mtb) or HIV in China.
Autorzy:
Li L; Department of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, #1 Jianshe East Road, 450052, Zhengzhou, China.; State Key Laboratory of Antiviral Drugs, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.; Precision Medicine Center, Gene Hospital of Henan Province, the First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Zhang J; Department of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, #1 Jianshe East Road, 450052, Zhengzhou, China.; State Key Laboratory of Antiviral Drugs, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.; Precision Medicine Center, Gene Hospital of Henan Province, the First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Sun R; Department of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, #1 Jianshe East Road, 450052, Zhengzhou, China.; State Key Laboratory of Antiviral Drugs, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.; Precision Medicine Center, Gene Hospital of Henan Province, the First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Liu H; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Cheng G; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Fan F; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Wang C; Department of Hematology, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Li A; Department of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, #1 Jianshe East Road, 450052, Zhengzhou, China.; State Key Laboratory of Antiviral Drugs, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.; Precision Medicine Center, Gene Hospital of Henan Province, the First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Liang H; Department of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, #1 Jianshe East Road, 450052, Zhengzhou, China.; State Key Laboratory of Antiviral Drugs, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.; Precision Medicine Center, Gene Hospital of Henan Province, the First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China.
Yu Z; Department of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, #1 Jianshe East Road, 450052, Zhengzhou, China. .; State Key Laboratory of Antiviral Drugs, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China. .; Precision Medicine Center, Gene Hospital of Henan Province, the First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China. .
Wang G; Department of Infectious Diseases and the Center for Liver Diseases, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, 100034, Beijing, China. .
Ren Z; Department of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, #1 Jianshe East Road, 450052, Zhengzhou, China. .; State Key Laboratory of Antiviral Drugs, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China. .; Precision Medicine Center, Gene Hospital of Henan Province, the First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, China. .
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Źródło:
BMC public health [BMC Public Health] 2024 Feb 22; Vol. 24 (1), pp. 556. Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Coinfection*/epidemiology
HIV Infections*/complications
HIV Infections*/epidemiology
COVID-19*
Humans ; SARS-CoV-2 ; Retrospective Studies ; Cytokines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
TB-DROP: deep learning-based drug resistance prediction of Mycobacterium tuberculosis utilizing whole genome mutations.
Autorzy:
Wang Y; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resources and Eco-Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064, China.
Jiang Z; Key Laboratory of Bio-Resources and Eco-Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064, China.
Liang P; Key Laboratory of Bio-Resources and Eco-Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064, China.; Zhejiang Yangshengtang Institute of Natural Medication Co., Ltd, Hangzhou, China.
Liu Z; Key Laboratory of Bio-Resources and Eco-Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064, China.
Cai H; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resources and Eco-Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064, China. .
Sun Q; Key Laboratory of Bio-Resources and Eco-Environment of the Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610064, China. .
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Źródło:
BMC genomics [BMC Genomics] 2024 Feb 12; Vol. 25 (1), pp. 167. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*/genetics
Deep Learning*
Tuberculosis*/microbiology
Tuberculosis, Multidrug-Resistant*/drug therapy
Humans ; Antitubercular Agents/pharmacology ; Antitubercular Agents/therapeutic use ; Mutation ; Microbial Sensitivity Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Metabolites from Streptomyces aureus (VTCC43181) and Their Inhibition of Mycobacterium tuberculosis ClpC1 Protein.
Autorzy:
Tran TTP; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST),18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.; Faculty of Chemistry, Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.
Huynh NNT; Faculty of Chemistry, Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.; Faculty of Natural Sciences, Phu Yen University, 01 Nguyen Van Huyen Road, Tuy Hoa City 56000, Vietnam.
Pham NT; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST),18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.
Nguyen DT; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST),18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.
Tran CV; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST),18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.
Nguyen UQ; Institute of Microbiology and Biotechnology, Vietnam National University Hanoi, 44, Xuan Thuy Road, Cau Giay, Hanoi 10000, Vietnam.
Ho AN; Institute of Biotechnology, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.
Suh JW; Center for Nutraceutical and Pharmaceutical Materials, Myongji University, Yongin 17058, Republic of Korea.
Cheng J; Center for Nutraceutical and Pharmaceutical Materials, Myongji University, Yongin 17058, Republic of Korea.
Nguyen TKN; Faculty of Biology, University of Natural Sciences, Vietnam National University, Hanoi, 334 Nguyen Trai Road, Thanh Xuân, Hanoi 10000, Vietnam.
Tran SV; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST),18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.; Faculty of Chemistry, Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.
Nguyen DM; Institute of Genome Research, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet Road, Cau Giay, Hanoi 10000, Vietnam.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 04; Vol. 29 (3). Date of Electronic Publication: 2024 Feb 04.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Streptomyces*
Staphylococcus aureus/metabolism ; Antitubercular Agents/pharmacology ; Antitubercular Agents/metabolism ; Bacterial Proteins/chemistry ; Adenosine Triphosphatases/metabolism
SCR Organism:
Streptomyces aureus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Revealing the Interaction Mechanism between Mycobacterium tuberculosis GyrB and Novobiocin, SPR719 through Binding Thermodynamics and Dissociation Kinetics Analysis.
Autorzy:
Qiu X; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Zhang Q; Faculty of Applied Science, Macao Polytechnic University, Macao SAR, China.
Li Z; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Zhang J; School of Pharmacy, Lanzhou University, Lanzhou 730000, China.
Liu H; Faculty of Applied Science, Macao Polytechnic University, Macao SAR, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 28; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Novobiocin/pharmacology ; Thermodynamics ; Antitubercular Agents/pharmacology ; Molecular Dynamics Simulation ; Adenosine Triphosphate
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The use of Kudoh method for culture of Mycobacterium tuberculosis and Mycobacterium africanum in The Gambia.
Autorzy:
Jobarteh T; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Otu J; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Gitteh E; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Mendy FS; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Faal-Jawara TI; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Ofori-Anyinam B; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.; Rutgers New Jersey Medical School, Newark, New Jersey, United States of America.
Sarr B; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Riley AJ; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Ayorinde A; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
de Jong BC; Institute for Tropical Medicine, Antwerp, Belgium.
Kampmann B; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Secka O; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Gehre F; Medical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.; Institute for Tropical Medicine, Antwerp, Belgium.; Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany.
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Źródło:
PloS one [PLoS One] 2024 Mar 27; Vol. 19 (3), pp. e0300042. Date of Electronic Publication: 2024 Mar 27 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Tuberculosis*/diagnosis
Tuberculosis*/microbiology
Humans ; Gambia ; Sodium Hydroxide ; Bacteriological Techniques/methods ; Sputum/microbiology ; Culture Media
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular docking, molecular dynamics simulations and binding free energy studies of interactions between Mycobacterium tuberculosis Pks13, PknG and bioactive constituents of extremophilic bacteria.
Autorzy:
Nyambo K; DST-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.
Tapfuma KI; DST-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.
Adu-Amankwaah F; DST-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.
Julius L; DST-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.
Baatjies L; DST-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.
Niang IS; Department of Biotechnology and Biochemistry, University of Zimbabwe, B064, Mount Pleasant, Harare, Zimbabwe.
Smith L; DST-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.
Govender KK; Department of Chemical Sciences, University of Johannesburg, Doornfontein Campus, P.O. Box 17011, Johannesburg, 2028, South Africa.; National Institute for Theoretical and Computational Sciences (NITheCS), Cape Town, South Africa.
Ngxande M; Computer Science Division, Department of Mathematical Sciences, Faculty of Science, University of Stellenbosch, Matieland, South Africa.
Watson DJ; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Wiesner L; Division of Clinical Pharmacology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Mavumengwana V; DST-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 21; Vol. 14 (1), pp. 6794. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*/genetics
Biological Products*/pharmacology
Mycobacteriaceae*
Molecular Dynamics Simulation ; Molecular Docking Simulation ; RNA, Ribosomal, 16S ; Anti-Bacterial Agents/pharmacology ; Mycobacterium smegmatis/genetics ; Complex Mixtures ; Antitubercular Agents/pharmacology ; Antitubercular Agents/chemistry
SCR Organism:
Mycolicibacterium aurum
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Fluvastatin Converts Human Macrophages into Foam Cells with Increased Inflammatory Response to Inactivated Mycobacterium tuberculosis H37Ra .
Autorzy:
Montero-Vega MT; Servicio de Bioquímica-Investigación, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.
Matilla J; Servicio de Bioquímica-Investigación, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.
Bazán E; Servicio de Neurobiología-Investigación, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.
Reimers D; Servicio de Neurobiología-Investigación, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.
De Andrés-Martín A; Servicio de Inmunología, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.
Gonzalo-Gobernado R; Departamento de Biología Molecular y Celular, Centro Nacional de Biotecnología (CNB), Consejo Superior de Investigaciones Científicas (CSIC), 28049 Madrid, Spain.
Correa C; Unidad de Cirugía Experimental y Animalario, Investigación, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.
Urbano F; Servicio Interdepartamental de Investigación (SIdI), Facultad de Medicina, Universidad Autónoma, 28029 Madrid, Spain.
Gómez-Coronado D; Servicio de Bioquímica-Investigación, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), 28034 Madrid, Spain.
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Źródło:
Cells [Cells] 2024 Mar 18; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Hydroxymethylglutaryl-CoA Reductase Inhibitors*
Tuberculosis*
Animals ; Humans ; Rabbits ; Fluvastatin/metabolism ; Foam Cells/metabolism ; Leukocytes, Mononuclear/metabolism ; Macrophages/metabolism ; Cholesterol/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transposon sequencing reveals metabolic pathways essential for Mycobacterium tuberculosis infection.
Autorzy:
Block AM; Department of Microbiology and Immunology, University of Minnesota, Twin Cities Campus, Minneapolis, Minnesota, United States of America.
Wiegert PC; Department of Microbiology and Immunology, University of Minnesota, Twin Cities Campus, Minneapolis, Minnesota, United States of America.
Namugenyi SB; Department of Microbiology and Immunology, University of Minnesota, Twin Cities Campus, Minneapolis, Minnesota, United States of America.
Tischler AD; Department of Microbiology and Immunology, University of Minnesota, Twin Cities Campus, Minneapolis, Minnesota, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Mar 18; Vol. 20 (3), pp. e1011663. Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Tuberculosis*/genetics
Mycobacterium tuberculosis*/genetics
Animals ; Mice ; Mutation ; Metabolic Networks and Pathways/genetics ; Thiamine ; Purines ; Mammals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice.
Autorzy:
Yang F; Department of Medicine, The University of Texas at Tyler School of Medicine, Tyler, TX, USA.; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Labani-Motlagh A; Department of Medicine, The University of Texas at Tyler School of Medicine, Tyler, TX, USA.; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Center for Discovery and Innovation, Hackensack Meridian Health, Hackensack, NJ, USA.
Bohorquez JA; Department of Medicine, The University of Texas at Tyler School of Medicine, Tyler, TX, USA.; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Moreira JD; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Ansari D; Department of Medicine, The University of Texas at Tyler School of Medicine, Tyler, TX, USA.; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Patel S; Department of Medicine, The University of Texas at Tyler School of Medicine, Tyler, TX, USA.; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Spagnolo F; Life Sciences Department, Long Island University Post, Brookville, NY, USA.
Florence J; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Vankayalapati A; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Sakai T; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Sato O; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Ikebe M; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Vankayalapati R; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA.
Dennehy JJ; Biology Department, Queens College of The City University of New York, Flushing, NY, USA. .; The Graduate Center of The City University of New York, New York, NY, USA. .
Samten B; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA. .; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA. .
Yi G; Department of Medicine, The University of Texas at Tyler School of Medicine, Tyler, TX, USA. .; Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX, USA. .; Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX, USA. .
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Źródło:
Communications biology [Commun Biol] 2024 Mar 09; Vol. 7 (1), pp. 294. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Phage Therapy*
Tuberculosis*/therapy
Tuberculosis*/microbiology
Animals ; Mice ; Humans ; Macrophages/microbiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice.
Autorzy:
Kurtz SL; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Baker RE; Department of Microbiology and Physiological Systems, UMass Chan Medical School, Worcester, Massachusetts, United States of America.
Boehm FJ; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
Lehman CC; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Mittereder LR; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Khan H; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
Rossi AP; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.; College of Medicine, University of Cincinatti, Cincinatti, Ohio, United States of America.
Gatti DM; The Jackson Laboratory, Bar Harbor, Maine, United States of America.
Beamer G; Texas Biomedical Research Institute, San Antonio, Texas, United States of America.
Sassetti CM; Department of Microbiology and Physiological Systems, UMass Chan Medical School, Worcester, Massachusetts, United States of America.
Elkins KL; Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Mar 07; Vol. 20 (3), pp. e1012069. Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*
Tuberculosis*/genetics
Tuberculosis*/prevention & control
Tuberculosis*/microbiology
Tuberculosis Vaccines*/genetics
Mycobacterium bovis*
Humans ; Animals ; Mice ; BCG Vaccine/genetics ; Vaccination ; Genetic Loci ; Cytokines/genetics ; Antigens, Bacterial
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
α-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site.
Autorzy:
Mojanaga OO; Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, UK.
Woodman TJ; Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, UK.
Lloyd MD; Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, UK.
Acharya KR; Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, UK.
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Źródło:
Biomolecules [Biomolecules] 2024 Mar 02; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Mycobacterium tuberculosis*/genetics
Catalytic Domain ; Kinetics ; Racemases and Epimerases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 284089

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