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Tytuł:
Detection of prions from spiked and free-ranging carnivore feces.
Autorzy:
Inzalaco HN; Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, University of Wisconsin, Madison, Madison, WI, 53706, USA. .
Brandell EE; Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, University of Wisconsin, Madison, Madison, WI, 53706, USA.
Wilson SP; Nebraska Game and Parks Commission, 2200 N 33rd St., P.O. Box 30370, Lincoln, NE, 68503, USA.
Hunsaker M; Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, University of Wisconsin, Madison, Madison, WI, 53706, USA.
Stahler DR; Yellowstone Center for Resources, Yellowstone National Park, WY, 82190, USA.
Woelfel K; Wild and Free Wildlife Rehabilitation Program, 27264 MN-18, Garrison, MN, 56450, USA.
Walsh DP; U.S. Geological Survey, Montana Cooperative Wildlife Research Unit, University of Montana, Missoula, MT, USA.
Nordeen T; Nebraska Game and Parks Commission, 2200 N 33rd St., P.O. Box 30370, Lincoln, NE, 68503, USA.
Storm DJ; Wisconsin Department of Natural Resources, Eau Claire, WI, 54701, USA.
Lichtenberg SS; Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN, 55108, USA.
Turner WC; U.S. Geological Survey, Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, University of Wisconsin - Madison, Madison, WI, 53706, USA.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 15; Vol. 14 (1), pp. 3804. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Prions*
Neurodegenerative Diseases*
Wasting Disease, Chronic*/diagnosis
Wasting Disease, Chronic*/epidemiology
Deer*
Coyotes*
Animals ; Feces
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Detection of prions in matching post-mortem skin and cerebrospinal fluid samples using second-generation real-time quaking-induced conversion assay.
Autorzy:
Baranová S; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Moško T; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Brůžová M; Department of Pathology and Molecular Medicine, Third Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic.
Haldiman T; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Kim C; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Safar JG; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.
Matěj R; Department of Pathology and Molecular Medicine, Third Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic.; Department of Pathology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic.; Department of Pathology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Holada K; Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University, Prague, Czech Republic. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 15; Vol. 14 (1), pp. 6294. Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:
Journal Article
MeSH Terms:
Prions*/metabolism
Prion Diseases*/diagnosis
Creutzfeldt-Jakob Syndrome*/diagnosis
Creutzfeldt-Jakob Syndrome*/cerebrospinal fluid
Humans ; Skin/metabolism ; Prion Proteins ; Biological Assay
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
New Light on Prions: Putative Role of PrP in Pathophysiology of Mood Disorders.
Autorzy:
Chrobak AA; Department of Adult Psychiatry, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.
Pańczyszyn-Trzewik P; Department of Human Physiology, Institute of Medical Sciences, Medical College of Rzeszow University, Kopisto 2a, 35-959 Rzeszow, Poland.
Król P; Department of Adult Psychiatry, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.
Pawelec-Bąk M; Department of Affective Disorders, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.
Dudek D; Department of Adult Psychiatry, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.
Siwek M; Department of Affective Disorders, Jagiellonian University Medical College, Kopernika 21A, 31-501 Kraków, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 04; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Creutzfeldt-Jakob Syndrome*/metabolism
Prions*/metabolism
PrPC Proteins*
Humans ; Mood Disorders ; Neuronal Plasticity ; Synaptic Transmission
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Viroids, Satellite RNAs and Prions: Folding of Nucleic Acids and Misfolding of Proteins.
Autorzy:
Steger G; Institut für Physikalische Biologie, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, 40204 Düsseldorf, Germany.
Riesner D; Institut für Physikalische Biologie, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, 40204 Düsseldorf, Germany.
Prusiner SB; Institute for Neurodegenerative Diseases, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA 94158, USA.; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA.
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Źródło:
Viruses [Viruses] 2024 Feb 26; Vol. 16 (3). Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Viroids*/genetics
Viroids*/metabolism
Prions*
Nucleic Acids*
Animals ; RNA, Satellite/genetics ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Plant Diseases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Detection of prions in the urine of patients affected by sporadic Creutzfeldt-Jakob disease.
Autorzy:
Pritzkow S; Department of Neurology, Mitchell Center for Alzheimer's Disease and Related Brain Disorders, University of Texas McGovern Medical School at Houston, Houston, Texas, USA.
Ramirez F; Department of Neurology, Mitchell Center for Alzheimer's Disease and Related Brain Disorders, University of Texas McGovern Medical School at Houston, Houston, Texas, USA.
Lyon A; Department of Neurology, Mitchell Center for Alzheimer's Disease and Related Brain Disorders, University of Texas McGovern Medical School at Houston, Houston, Texas, USA.
Schulz PE; Department of Neurology, Mitchell Center for Alzheimer's Disease and Related Brain Disorders, University of Texas McGovern Medical School at Houston, Houston, Texas, USA.
Appleby B; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
Moda F; Division of Neurology 5 - Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Ramirez S; Department of Neurology, Mitchell Center for Alzheimer's Disease and Related Brain Disorders, University of Texas McGovern Medical School at Houston, Houston, Texas, USA.
Notari S; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
Gambetti P; Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
Soto C; Department of Neurology, Mitchell Center for Alzheimer's Disease and Related Brain Disorders, University of Texas McGovern Medical School at Houston, Houston, Texas, USA.
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Źródło:
Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2023 Dec; Vol. 10 (12), pp. 2316-2323. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Creutzfeldt-Jakob Syndrome*/diagnosis
Prions*
Humans ; Brain/metabolism
SCR Disease Name:
Creutzfeldt-Jakob Disease, Sporadic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation.
Autorzy:
Eraña H; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.; ATLAS Molecular Pharma S. L. Bizkaia Technology Park, 48160, Derio, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Carlos III National Health Institute, 28029, Madrid, Spain.
Díaz-Domínguez CM; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Carlos III National Health Institute, 28029, Madrid, Spain.
Charco JM; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.; ATLAS Molecular Pharma S. L. Bizkaia Technology Park, 48160, Derio, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Carlos III National Health Institute, 28029, Madrid, Spain.
Vidal E; IRTA, Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, Spain.
González-Miranda E; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Pérez-Castro MA; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Piñeiro P; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
López-Moreno R; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Sampedro-Torres-Quevedo C; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Fernández-Veiga L; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Tasis-Galarza J; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Lorenzo NL; CIMUS Biomedical Research Institute and Department of Medical Sciences, University of Santiago de Compostela-IDIS, 15782, Santiago de Compostela, Spain.
Santini-Santiago A; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Lázaro M; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
García-Martínez S; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Gonçalves-Anjo N; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
San-Juan-Ansoleaga M; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Galarza-Ahumada J; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Fernández-Muñoz E; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Giler S; IRTA, Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Catalonia, Spain.
Valle M; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain.
Telling GC; Prion Research Center (PRC), Colorado State University, Fort Collins, CO, 80523, USA.
Geijó M; Animal Health Department, NEIKER-Basque Institute for Agricultural Research and Development, Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Spain.
Requena JR; CIMUS Biomedical Research Institute and Department of Medical Sciences, University of Santiago de Compostela-IDIS, 15782, Santiago de Compostela, Spain.
Castilla J; Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, 48160, Derio, Bizkaia, Spain. .; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Carlos III National Health Institute, 28029, Madrid, Spain. .; IKERBASQUE, Basque Foundation for Science, 48011, Bilbao, Spain. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Sep 07; Vol. 11 (1), pp. 145. Date of Electronic Publication: 2023 Sep 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Prions*
Creutzfeldt-Jakob Syndrome*
Humans ; Magnetic Resonance Imaging ; Tremor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sequestrase chaperones protect against oxidative stress-induced protein aggregation and [PSI+] prion formation.
Autorzy:
Carter Z; Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, United Kingdom.
Creamer D; Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, United Kingdom.
Kouvidi A; Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, United Kingdom.
Grant CM; Faculty of Biology, Medicine and Health, School of Biological Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, United Kingdom.
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Źródło:
PLoS genetics [PLoS Genet] 2024 Feb 29; Vol. 20 (2), pp. e1011194. Date of Electronic Publication: 2024 Feb 29 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Prions*/genetics
Prions*/metabolism
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Protein Aggregates/genetics ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Oxidative Stress/genetics ; Amyloid/metabolism ; Oxidants/pharmacology ; Oxidants/metabolism ; Peptide Termination Factors/genetics ; Peptide Termination Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Single nucleotide polymorphisms (SNPs) in the open reading frame (ORF) of prion protein gene (PRNP) in Nigerian livestock species.
Autorzy:
Adeola AC; State Key Laboratory of Genetic Resources and Evolution & Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China. .; Sino-Africa Joint Research Center, Chinese Academy of Sciences, Kunming, China. .
Bello SF; Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, 510642, Guangzhou, China.
Abdussamad AM; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, Bayero University, Kano, Nigeria.
Adedokun RAM; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Olaogun SC; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Abdullahi N; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, Bayero University, Kano, Nigeria.
Mark AI; Ministry of Agriculture and Rural Development, Secretariat, Ibadan, Nigeria.
Onoja AB; Department of Virology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Sanke OJ; Taraba State Ministry of Agriculture and Natural Resources, Jalingo, Nigeria.
Mangbon GF; Division of Veterinary Office, Serti, Nigeria.
Ibrahim J; Department of Veterinary Surgery and Theriogenology, College of Veterinary Medicine, University of Agriculture Makurdi, Makurdi, Nigeria.
Dawuda PM; Department of Animal Science, Faculty of Agriculture, National University of Lesotho, Maseru, South Africa.
Salako AE; Department of Animal Science, Faculty of Agriculture, University of Ibadan, Ibadan, Nigeria.
Kdidi S; Livestock and Wildlife Laboratory, Institut des Régions Arides, Université de Gabes, Route El Djorf, Km 22.5, 4119, Medenine, Tunisia.
Yahyaoui MH; Livestock and Wildlife Laboratory, Institut des Régions Arides, Université de Gabes, Route El Djorf, Km 22.5, 4119, Medenine, Tunisia.
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Źródło:
BMC genomics [BMC Genomics] 2024 Feb 14; Vol. 25 (1), pp. 177. Date of Electronic Publication: 2024 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Prions*/genetics
Prions*/metabolism
Prion Diseases*/genetics
Prion Diseases*/veterinary
Scrapie*/genetics
Animals ; Horses/genetics ; Sheep/genetics ; Dogs ; Prion Proteins/genetics ; Polymorphism, Single Nucleotide ; Livestock/genetics ; Open Reading Frames ; Phylogeny ; Camelus/genetics ; Goats/genetics ; Goats/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas.
Autorzy:
Boccacino JM; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Dos Santos Peixoto R; Department of Automation and Systems, Technological Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Fernandes CFL; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Cangiano G; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Sola PR; Cellular and Molecular Biology Laboratory (LIM 15), Department of Neurology, Faculdade de Medicina (FMUSP), University of Sao Paulo, Sao Paulo, Brazil.
Coelho BP; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Prado MB; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Melo-Escobar MI; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
de Sousa BP; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil.
Ayyadhury S; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Bader GD; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.
Shinjo SMO; Cellular and Molecular Biology Laboratory (LIM 15), Department of Neurology, Faculdade de Medicina (FMUSP), University of Sao Paulo, Sao Paulo, Brazil.
Marie SKN; Cellular and Molecular Biology Laboratory (LIM 15), Department of Neurology, Faculdade de Medicina (FMUSP), University of Sao Paulo, Sao Paulo, Brazil.
da Rocha EL; Department of Microbiology, Immunology, and Parasitology, Biological Sciences Center, Federal University of Santa Catarina, Florianópolis, Santa Catarina, 88040-900, Brazil. .
Lopes MH; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 1524 room 431, Sao Paulo, 05508000, Brazil. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Feb 13; Vol. 24 (1), pp. 199. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Glioblastoma*/genetics
Glioblastoma*/pathology
Prions*/genetics
Prions*/metabolism
Humans ; Gene Expression ; Gene Expression Profiling ; Prion Proteins/genetics ; Prion Proteins/metabolism ; rab GTP-Binding Proteins/genetics ; Synaptophysin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ticks harbor and excrete chronic wasting disease prions.
Autorzy:
Inzalaco HN; Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, University of Wisconsin, Madison, Madison, WI, 53706, USA. .
Bravo-Risi F; Department of Neurology, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Centro Integrativo de Biologia y Quimica Aplicada (CIBQA), Universidad Bernardo O'Higgins, Santiago, Chile.
Morales R; Department of Neurology, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Centro Integrativo de Biologia y Quimica Aplicada (CIBQA), Universidad Bernardo O'Higgins, Santiago, Chile.
Walsh DP; U.S. Geological Survey, Montana Cooperative Wildlife Research Unit, University of Montana, Missoula, MT, USA.
Storm DJ; Wisconsin Department of Natural Resources, Eau Claire, WI, USA.
Pedersen JA; Environmental Health and Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
Turner WC; Wisconsin Cooperative Wildlife Research Unit, Department of Forest and Wildlife Ecology, U.S. Geological Survey, University of Wisconsin - Madison, Madison, WI, 53706, USA.
Lichtenberg SS; Department of Soil Science, University of Wisconsin, Madison, Madison, WI, USA.
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Źródło:
Scientific reports [Sci Rep] 2023 May 15; Vol. 13 (1), pp. 7838. Date of Electronic Publication: 2023 May 15.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Prions*/metabolism
Deer*/metabolism
Wasting Disease, Chronic*/metabolism
Neurodegenerative Diseases*
Ixodes*/metabolism
Animals
SCR Organism:
Odocoileus virginianus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prions are the greatest protein misfolding problem, and yeast has several solutions.
Autorzy:
Wickner RB; Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Edskes HK; Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Wu S; Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Gregg K; Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 May 04; Vol. 19 (5), pp. e1011333. Date of Electronic Publication: 2023 May 04 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Prions*/metabolism
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomyces cerevisiae/metabolism ; Protein Folding
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease.
Autorzy:
Walsh DJ; Department of Biochemistry and Cell Biology Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
Rees JR; Department of Epidemiology Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.; Department of Community and Family Medicine Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
Mehra S; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
Bourkas MEC; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Kaczmarczyk L; Wallenberg Center for Molecular Medicine, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Stuart E; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Jackson WS; Wallenberg Center for Molecular Medicine, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Watts JC; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Supattapone S; Department of Biochemistry and Cell Biology Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.; Department of Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Apr 01; Vol. 20 (4), pp. e1012087. Date of Electronic Publication: 2024 Apr 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Prions*/metabolism
Prion Diseases*/drug therapy
Prion Diseases*/genetics
Prion Diseases*/metabolism
Creutzfeldt-Jakob Syndrome*/drug therapy
Creutzfeldt-Jakob Syndrome*/genetics
Creutzfeldt-Jakob Syndrome*/metabolism
Animals ; Mice ; Prion Proteins/genetics ; Prion Proteins/metabolism ; Brain/pathology ; Arvicolinae/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mapping of Prion Structures in the Yeast Rnq1.
Autorzy:
Galliamov AA; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Moscow 119071, Russia.
Malukhina AD; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Moscow 119071, Russia.; Department of Biology, Moscow State University, Moscow 119991, Russia.
Kushnirov VV; A.N. Bach Institute of Biochemistry, Federal Research Center 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, Moscow 119071, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 17; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 17.
Typ publikacji:
Journal Article
MeSH Terms:
Prions*/metabolism
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Detection limitations of prion seeding activities in blood samples from patients with sporadic prion disease.
Autorzy:
Nonaka T; Division of Cellular and Molecular Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, 852-8501, Japan.
Iwasaki Y; Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, Nagakute City, 480-1195, Japan.
Horiuchi H; Laboratory of Immunobiology, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima City, Japan.
Satoh K; Department of Health Sciences, Unit of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, Japan. .
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Źródło:
BMC neurology [BMC Neurol] 2024 Mar 11; Vol. 24 (1), pp. 92. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:
Journal Article
MeSH Terms:
Prions*/metabolism
Prion Diseases*/diagnosis
Prion Diseases*/metabolism
Creutzfeldt-Jakob Syndrome*/diagnosis
Humans ; Prion Proteins ; Brain/metabolism ; Plasma/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
N-Glycosylation as a Modulator of Protein Conformation and Assembly in Disease.
Autorzy:
Pasala C; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Sharma S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Roychowdhury T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Moroni E; The Institute of Chemical Sciences and Technologies (SCITEC), Italian National Research Council (CNR), 20131 Milano, Italy.
Colombo G; The Institute of Chemical Sciences and Technologies (SCITEC), Italian National Research Council (CNR), 20131 Milano, Italy.; Department of Chemistry, University of Pavia, 27100 Pavia, Italy.
Chiosis G; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
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Źródło:
Biomolecules [Biomolecules] 2024 Feb 27; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Protein Processing, Post-Translational*
Prions*/metabolism
Glycosylation ; Polysaccharides/chemistry ; Protein Conformation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease.
Autorzy:
Ward A; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Jessop F; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Faris R; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America.
Hollister J; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Shoup D; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Race B; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Bosio CM; Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
Priola SA; Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana.
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Źródło:
PloS one [PLoS One] 2024 Feb 23; Vol. 19 (2), pp. e0298095. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Neurodegenerative Diseases*
Prion Diseases*/genetics
Prions*
Mice ; Animals ; Mitophagy ; Protein Kinases/genetics ; Protein Kinases/metabolism ; Reactive Oxygen Species/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Temporal serum neurofilament light chain concentrations in sheep inoculated with the agent of classical scrapie.
Autorzy:
Brown Q; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America.; Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Christensen, Ames, United States of America.
Nicholson E; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.
Wang C; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America.
Greenlee J; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.
Seger H; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, United States of America.
Veneziano S; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.
Cassmann E; United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, Iowa, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Feb 23; Vol. 19 (2), pp. e0299038. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Scrapie*/genetics
Prions*/metabolism
Humans ; Sheep ; Animals ; PrPSc Proteins/metabolism ; Intermediate Filaments/metabolism ; Brain/metabolism ; Biomarkers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Strain-Dependent Morphology of Reactive Astrocytes in Human- and Animal-Vole-Adapted Prions.
Autorzy:
Bruno R; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Riccardi G; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Iacobone F; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Chiarotti F; Reference Center for the Behavioral Sciences and Mental Health, Italian National Institute of Health, 00161 Rome, Italy.
Pirisinu L; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Vanni I; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Marcon S; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
D'Agostino C; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Giovannelli M; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Parchi P; IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139 Bologna, Italy.; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138 Bologna, Italy.
Agrimi U; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Nonno R; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Di Bari MA; Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
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Źródło:
Biomolecules [Biomolecules] 2023 Apr 27; Vol. 13 (5). Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Prions*/metabolism
Prion Diseases*/pathology
Animals ; Humans ; Astrocytes/metabolism ; Arvicolinae/genetics ; Arvicolinae/metabolism ; Gliosis/pathology ; Brain/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of α-synuclein prion strains in Parkinson's disease and multiple system atrophy.
Autorzy:
Khedmatgozar CR; Department of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, United States of America.
Holec SAM; Department of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, United States of America.
Woerman AL; Department of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Jan 25; Vol. 20 (1), pp. e1011920. Date of Electronic Publication: 2024 Jan 25 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Parkinson Disease*
Multiple System Atrophy*
Prions*
Humans ; alpha-Synuclein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 42366

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