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Tytuł:
ERBB1 alleviates secondary brain injury induced by experimental intracerebral hemorrhage in rats by modulating neuronal death via PLC-γ/PKC pathway.
Autorzy:
Li B; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.; Department of Neurosurgery, Yancheng City No. 1 People's Hospital, Yancheng First Hospital, Affiliated Hospital of Nanjing University Medical School, Yancheng, Jiangsu Province, China.
Wu J; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Cao D; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.; Department of Neurosurgery, The Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu Province, China.
Cao C; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.; Department of Neurocritical Intensive Care Unit, Jiangyin Clinical College of Xuzhou Medical College, Jiangyin, Jiangsu Province, China.
Zhang J; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Li X; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Li H; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Shen H; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
Yu Z; Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14679.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Injuries*/metabolism
Cerebral Hemorrhage*/complications
Cerebral Hemorrhage*/metabolism
Quinazolines*
ErbB Receptors*/metabolism
Animals ; Rats ; Apoptosis ; Cytokines/metabolism ; Phospholipase C gamma/metabolism ; Rats, Sprague-Dawley ; Tyrphostins ; Protein Kinase C/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Real-Life Data on the Efficacy and Safety of Letermovir for Primary Prophylaxis of Cytomegalovirus in Allogeneic Hematopoietic Stem Cell Recipients: A Single-Center Analysis
Autorzy:
Włodarczyk M; Medical University of Silesia, Faculty of Medicine in Katowice, Department of Hematology and Bone Marrow Transplantation, Katowice, Poland
Wieczorkiewicz-Kabut A; Medical University of Silesia, Faculty of Medicine in Katowice, Department of Hematology and Bone Marrow Transplantation, Katowice, Poland
Białas K; Medical University of Silesia, Faculty of Medicine in Katowice, Department of Hematology and Bone Marrow Transplantation, Katowice, Poland
Koclęga A; Medical University of Silesia, Faculty of Medicine in Katowice, Department of Hematology and Bone Marrow Transplantation, Katowice, Poland
Noster I; Medical University of Silesia, Faculty of Medicine in Katowice, Department of Hematology and Bone Marrow Transplantation, Katowice, Poland
Zielińska P; Medical University of Silesia, Faculty of Medicine in Katowice, Department of Hematology and Bone Marrow Transplantation, Katowice, Poland
Helbig G; Medical University of Silesia, Faculty of Medicine in Katowice, Department of Hematology and Bone Marrow Transplantation, Katowice, Poland
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Źródło:
Turkish journal of haematology : official journal of Turkish Society of Haematology [Turk J Haematol] 2024 Mar 01; Vol. 41 (1), pp. 9-15. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Cytomegalovirus Infections*/drug therapy
Cytomegalovirus Infections*/etiology
Cytomegalovirus Infections*/prevention & control
Hematopoietic Stem Cell Transplantation*/adverse effects
Acetates*
Quinazolines*
Adult ; Humans ; Young Adult ; Middle Aged ; Aged ; Cytomegalovirus ; Antiviral Agents/adverse effects ; Retrospective Studies ; Transplantation, Homologous/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
3-Aryl-5-aminobiphenyl Substituted [1,2,4]triazolo[4,3- c ]quinazolines: Synthesis and Photophysical Properties.
Autorzy:
Kopotilova AE; Department of Organic and Biomolecular Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia.
Moshkina TN; Department of Organic and Biomolecular Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia.
Nosova EV; Department of Organic and Biomolecular Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia.; I. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 620108 Ekaterinburg, Russia.
Lipunova GN; I. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 620108 Ekaterinburg, Russia.
Starnovskaya ES; Department of Organic and Biomolecular Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia.; I. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 620108 Ekaterinburg, Russia.
Kopchuk DS; Department of Organic and Biomolecular Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia.; I. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 620108 Ekaterinburg, Russia.
Kim GA; Department of Organic and Biomolecular Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia.; I. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 620108 Ekaterinburg, Russia.
Gaviko VS; Department of Organic and Biomolecular Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia.; M.N. Mikheev Institute of Metal Physics, Ural Branch of the Russian Academy of Sciences, 620108 Ekaterinburg, Russia.
Slepukhin PA; Department of Organic and Biomolecular Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia.; I. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 620108 Ekaterinburg, Russia.
Charushin VN; Department of Organic and Biomolecular Chemistry, Ural Federal University, 620002 Ekaterinburg, Russia.; I. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 620108 Ekaterinburg, Russia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 17; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Biphenyl Compounds*
Quinazolines*/chemistry
Molecular Conformation ; Toluene
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design and biological evaluation of 3-substituted quinazoline-2,4(1 H ,3 H )-dione derivatives as dual c-Met/VEGFR-2-TK inhibitors.
Autorzy:
Hassan A; Department of Medicinal Chemistry, Faculty of Pharmacy, South Valley University, Qena, Egypt.
Mubarak FAF; Department of Chemistry, Faculty of Science, South Valley University, Qena, Egypt.
Shehadi IA; Department of Chemistry, College of Sciences, Pure and Applied Chemistry Research Group, University of Sharjah, Sharjah, United Arab Emirates.
Mosallam AM; Department of Chemistry, Faculty of Science, South Valley University, Qena, Egypt.
Temairk H; Department of Chemistry, Faculty of Science, South Valley University, Qena, Egypt.
Badr M; Department of Biochemistry, Faculty of Pharmacy, Menoufia University, Menoufia, Egypt.
Abdelmonsef AH; Department of Chemistry, Faculty of Science, South Valley University, Qena, Egypt.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2189578.
Typ publikacji:
Journal Article
MeSH Terms:
Quinazolines*/pharmacology
Quinazolines*/chemistry
Antineoplastic Agents*/chemistry
Humans ; Structure-Activity Relationship ; Vascular Endothelial Growth Factor Receptor-2 ; Vascular Endothelial Growth Factor A ; Cell Proliferation ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry ; Molecular Docking Simulation ; Drug Screening Assays, Antitumor ; Molecular Structure ; Drug Design
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enhancing apoptosis-mediated anticancer activity of evodiamine through protein-based nanoparticles in breast cancer cells.
Autorzy:
Solanki R; School of Life Sciences, Central University of Gujarat, Gandhinagar, 382030, India.
Rajput PK; School of Life Sciences, Central University of Gujarat, Gandhinagar, 382030, India.
Jodha B; School of Life Sciences, Central University of Gujarat, Gandhinagar, 382030, India.
Yadav UCS; Special Centre for Medicine and Special Centre for Systems Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
Patel S; School of Life Sciences, Central University of Gujarat, Gandhinagar, 382030, India. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 31; Vol. 14 (1), pp. 2595. Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Nanoparticles*/chemistry
Quinazolines*
Humans ; Female ; Cell Line, Tumor ; Apoptosis ; Water
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A comprehensive review of recent advances in the biological activities of quinazolines.
Autorzy:
Gomaa HAM; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf, Saudi Arabia.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2022 Nov; Vol. 100 (5), pp. 639-655. Date of Electronic Publication: 2022 Aug 12.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Quinazolines*/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design, synthesis, computational study and cytotoxic evaluation of some new quinazoline derivatives containing pyrimidine moiety.
Autorzy:
Zare S; School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Emami L; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Faghih Z; Medical School, Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, Iran.
Zargari F; Pharmacology Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.; Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan (USB), Zahedan, Iran.
Faghih Z; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Khabnadideh S; Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 02; Vol. 13 (1), pp. 14461. Date of Electronic Publication: 2023 Sep 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Quinazolines*/pharmacology
Antineoplastic Agents*/pharmacology
Humans ; Pyrimidines/pharmacology ; Antimetabolites ; Quinazolinones/pharmacology ; Antihypertensive Agents
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Molecular Analysis of the Superior Efficacy of a Dual Epidermal Growth Factor Receptor (EGFR)-DNA-Targeting Combi-Molecule in Comparison with Its Putative Prodrugs 6-Mono-Alkylamino- and 6,6-Dialkylaminoquinazoline in a Human Osteosarcoma Xenograft Model.
Autorzy:
Facchin C; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada.
Fraga-Timiraos AB; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada.
Schmitt J; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada.
Babaa N; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada.
Pannu N; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada.
Aliaga A; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada.
Larroque AL; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada.
Jean-Claude BJ; Cancer Drug Research Laboratory, The Research Institute of the McGill University Health Center (RI-MUHC), Department of Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H4A 3J1, Canada.
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Źródło:
Cells [Cells] 2023 Mar 16; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ErbB Receptors*/drug effects
ErbB Receptors*/genetics
ErbB Receptors*/metabolism
Osteosarcoma*/drug therapy
Quinazolines*/pharmacology
Quinazolines*/therapeutic use
Animals ; Humans ; Mice ; DNA/chemistry ; Heterografts ; Prodrugs
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Novel Ambroxol-Derived Tetrahydroquinazoline with a Potency against SARS-CoV-2 Proteins.
Autorzy:
Krysantieva AI; Institute of Chemistry, University of Tyumen, Volodarskogo Str. 6, 625003 Tyumen, Russia.
Voronina JK; N.S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Leninsky prospekt 31, GSP-1, 119991 Moscow, Russia.
Safin DA; Institute of Chemistry, University of Tyumen, Volodarskogo Str. 6, 625003 Tyumen, Russia.; Scientific and Educational and Innovation Center for Chemical and Pharmaceutical Technologies, Ural Federal University Named after the First President of Russia B.N. Yeltsin, 620002 Ekaterinburg, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 28; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Ambroxol*/analogs & derivatives
Ambroxol*/pharmacokinetics
Ambroxol*/pharmacology
COVID-19*
SARS-CoV-2*/drug effects
SARS-CoV-2*/enzymology
Quinazolines*/chemistry
Quinazolines*/pharmacokinetics
Quinazolines*/pharmacology
Coronavirus Papain-Like Proteases*/antagonists & inhibitors
Coronavirus Papain-Like Proteases*/chemistry
Humans ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies.
Autorzy:
Altamimi AS; Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.
El-Azab AS; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Abdelhamid SG; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
Alamri MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.
Bayoumi AH; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
Alqahtani SM; Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.
Alabbas AB; Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.
Altharawi AI; Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.
Alossaimi MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.
Mohamed MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 May 18; Vol. 26 (10). Date of Electronic Publication: 2021 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Screening Assays, Antitumor*
Molecular Docking Simulation*
Antineoplastic Agents/*pharmacology
ErbB Receptors/*antagonists & inhibitors
Protein Kinase Inhibitors/*pharmacology
Quinazolines/*chemical synthesis
Quinazolines/*pharmacology
Vascular Endothelial Growth Factor Receptor-2/*antagonists & inhibitors
Antineoplastic Agents/analysis ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Biological Assay ; Cell Line, Tumor ; ErbB Receptors/metabolism ; Humans ; Inhibitory Concentration 50 ; Molecular Dynamics Simulation ; Protein Kinase Inhibitors/analysis ; Protein Kinase Inhibitors/chemistry ; Quinazolines/analysis ; Quinazolines/chemistry ; Vascular Endothelial Growth Factor Receptor-2/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Design, Synthesis and Biological Evaluation of 6-(Imidazo[1,2-a]pyridin-6-yl)quinazoline Derivatives as Anticancer Agents via PI3Kα Inhibition.
Autorzy:
Li M; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Wang D; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Li Q; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Luo F; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Zhong T; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Wu H; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Xiong L; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Yuan M; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Su M; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
Fan Y; State Key Laboratory for Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 06; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 06.
Typ publikacji:
Journal Article
MeSH Terms:
Quinazolines*/chemistry
Antineoplastic Agents*/chemistry
Molecular Structure ; Structure-Activity Relationship ; Phosphatidylinositol 3-Kinases/metabolism ; Drug Screening Assays, Antitumor ; Cell Proliferation ; Cell Line, Tumor ; Drug Design
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluation of the inhibitory effect of quercetin on the pharmacokinetics of tucatinib in rats by a novel UPLC-MS/MS assay.
Autorzy:
Zhang Y; Department of Pharmacy, HwaMei Hospital, University of Chinese Academy of Sciences (Ningbo No. 2 Hospital), Ningbo, China.; Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, China.
Liu YN; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xie S; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xu X; The Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Xu RA; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 621-626.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Chromatography, High Pressure Liquid/*methods
Oxazoles/*pharmacokinetics
Pyridines/*pharmacokinetics
Quercetin/*pharmacology
Quinazolines/*pharmacokinetics
Tandem Mass Spectrometry/*methods
Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/analysis ; Antineoplastic Agents/pharmacokinetics ; Area Under Curve ; Dose-Response Relationship, Drug ; Drug Interactions ; Limit of Detection ; Male ; Oxazoles/administration & dosage ; Oxazoles/analysis ; Pyridines/administration & dosage ; Pyridines/analysis ; Quercetin/administration & dosage ; Quinazolines/administration & dosage ; Quinazolines/analysis ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Annulation of Perimidines with 5-Alkynylpyrimidines en Route to 7-Formyl-1,3-Diazopyrenes.
Autorzy:
Shcherbakov SV; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Aksenov AV; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Vendin MV; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Shcherbakova VY; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Ivanova AY; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Shcheglov MO; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Ovcharov SN; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.
Rubin M; Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355017 Stavropol, Russia.; Department of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 10; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 10.
Typ publikacji:
Journal Article
MeSH Terms:
Quinazolines*
Acetylene*
Catalysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Ran-GTP/importin β inhibition on the meiotic division of porcine oocytes.
Autorzy:
He Y; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, No.1 Weigang, Nanjing, 210095, China.
Li J; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, No.1 Weigang, Nanjing, 210095, China.
Peng L; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, No.1 Weigang, Nanjing, 210095, China.
Li Q; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, No.1 Weigang, Nanjing, 210095, China. .
Chu Y; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, No.1 Weigang, Nanjing, 210095, China.
Lin Q; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, No.1 Weigang, Nanjing, 210095, China.
Dai J; Key Laboratory of Livestock and Poultry Resources (Pig) Evaluation and Utilization, Ministry of Agriculture and Rural Affairs, Institute of Animal Husbandry and Veterinary Science, Shanghai Academy of Agricultural Sciences, Shanghai, 201106, China.
Rui R; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, No.1 Weigang, Nanjing, 210095, China.
Ju S; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, No.1 Weigang, Nanjing, 210095, China. .
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Źródło:
Histochemistry and cell biology [Histochem Cell Biol] 2022 Dec; Vol. 158 (6), pp. 571-582. Date of Electronic Publication: 2022 Aug 05.
Typ publikacji:
Journal Article
MeSH Terms:
beta Karyopherins*
Quinazolines*
Swine ; Animals ; Signal Transduction ; Guanosine Triphosphate ; Mammals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Review on the Synthesis and Chemical Transformation of Quinazoline 3-Oxides.
Autorzy:
Mphahlele MJ; Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X06, Florida 1710, South Africa.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 17; Vol. 27 (22). Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Oxides*
Quinazolines*
Humans ; Chemistry, Pharmaceutical ; Research Personnel
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide.
Autorzy:
El-Azab AS; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Abdel-Aziz AA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Ghabbour HA; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Bua S; Department of Neurofarba, Sezione di Scienze Farmaceutiche Nutraceutiche, Università degli Studi di Firenze, Via U. Schiff 6, 50019 Sesto Fiorentino, Florence, Italy.
Nocentini A; Department of Neurofarba, Sezione di Scienze Farmaceutiche Nutraceutiche, Università degli Studi di Firenze, Via U. Schiff 6, 50019 Sesto Fiorentino, Florence, Italy.
Alkahtani HM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Alsaif NA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Al-Agamy MHM; Department of Pharmaceutics and Microbiology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Supuran CT; Department of Neurofarba, Sezione di Scienze Farmaceutiche Nutraceutiche, Università degli Studi di Firenze, Via U. Schiff 6, 50019 Sesto Fiorentino, Florence, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 09; Vol. 27 (22). Date of Electronic Publication: 2022 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Quinazolines*/pharmacology
Carbonic Anhydrases*/metabolism
Humans ; Structure-Activity Relationship ; Molecular Structure ; Isoenzymes/metabolism ; Carbonic Anhydrase Inhibitors/pharmacology ; Carbonic Anhydrase I ; Carbonic Anhydrase II ; Benzenesulfonamides
Czasopismo naukowe
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Wyświetlanie 1-20 z 13880

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