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Tytuł:
Genetic Dissection of BDNF and TrkB Expression in Glial Cells.
Autorzy:
Niu C; Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458, USA.; Skaggs Graduate School of Chemical and Biological Sciences, The Scripps Research Institute, Jupiter, FL 33458, USA.
Yue X; Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458, USA.; Skaggs Graduate School of Chemical and Biological Sciences, The Scripps Research Institute, Jupiter, FL 33458, USA.
An JJ; Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458, USA.
Bass R; Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458, USA.; Skaggs Graduate School of Chemical and Biological Sciences, The Scripps Research Institute, Jupiter, FL 33458, USA.
Xu H; Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458, USA.
Xu B; Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, University of Florida, Jupiter, FL 33458, USA.; Skaggs Graduate School of Chemical and Biological Sciences, The Scripps Research Institute, Jupiter, FL 33458, USA.
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Źródło:
Biomolecules [Biomolecules] 2024 Jan 11; Vol. 14 (1). Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Brain-Derived Neurotrophic Factor*/genetics
Neuroglia*
Receptor, trkB*/genetics
Animals ; Mice ; Astrocytes ; Microglia ; Oligodendroglia
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Regulation of Satiety by Bdnf-e2 -Expressing Neurons through TrkB Activation in Ventromedial Hypothalamus.
Autorzy:
Chu P; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.; School of Life Sciences, Tsinghua University, Beijing 100084, China.
Guo W; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.
You H; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.; School of Life Sciences, Tsinghua University, Beijing 100084, China.
Lu B; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.; Stellenbosch Institute for Advanced Study (STIAS), Wallenberg Centre, 10 Marais Street, Stellenbosch 7600, South Africa.
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Źródło:
Biomolecules [Biomolecules] 2023 May 11; Vol. 13 (5). Date of Electronic Publication: 2023 May 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain-Derived Neurotrophic Factor*/genetics
Brain-Derived Neurotrophic Factor*/metabolism
Receptor, trkB*/genetics
Receptor, trkB*/metabolism
Satiety Response*
Animals ; Mice ; Hyperphagia/genetics ; Hyperphagia/metabolism ; Hypothalamus/metabolism ; Neurons/metabolism ; Obesity/genetics ; Obesity/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BDNF/TrkB Is a Crucial Regulator in the Inflammation-Mediated Odontoblastic Differentiation of Dental Pulp Stem Cells.
Autorzy:
Kim JH; Department of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL 60612, USA.
Irfan M; Department of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL 60612, USA.
Hossain MA; Department of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL 60612, USA.
George A; Department of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL 60612, USA.
Chung S; Department of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL 60612, USA.
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Źródło:
Cells [Cells] 2023 Jul 14; Vol. 12 (14). Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Tumor Necrosis Factor-alpha*/pharmacology
Tumor Necrosis Factor-alpha*/metabolism
Receptor, trkB*/metabolism
Humans ; Tropomyosin/metabolism ; Brain-Derived Neurotrophic Factor/metabolism ; Dental Pulp ; Cell Differentiation ; Inflammation/metabolism ; Stem Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of mGluR5 alters BDNF/TrkB and GLT-1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD-like behavior in rats.
Autorzy:
Cheng S; Department of Medical Psychology and Ethics, School of Basic Medical Medicine Sciences, Cheeloo College of Medicine, Shandong University, 44#, Wenhua Xi Road, Jinan, Shandong, 250012, People's Republic of China.
Xu J; Department of Clinical Psychology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, 266035, Shandong, China.
Wang W; Department of Medical Psychology and Ethics, School of Basic Medical Medicine Sciences, Cheeloo College of Medicine, Shandong University, 44#, Wenhua Xi Road, Jinan, Shandong, 250012, People's Republic of China.
Wang R; Department of Medical Psychology and Ethics, School of Basic Medical Medicine Sciences, Cheeloo College of Medicine, Shandong University, 44#, Wenhua Xi Road, Jinan, Shandong, 250012, People's Republic of China.
Li H; Department of Medical Psychology and Ethics, School of Basic Medical Medicine Sciences, Cheeloo College of Medicine, Shandong University, 44#, Wenhua Xi Road, Jinan, Shandong, 250012, People's Republic of China.
Jiang Z; Department of Medical Psychology and Ethics, School of Basic Medical Medicine Sciences, Cheeloo College of Medicine, Shandong University, 44#, Wenhua Xi Road, Jinan, Shandong, 250012, People's Republic of China.
Liu D; Department of Medical Psychology and Ethics, School of Basic Medical Medicine Sciences, Cheeloo College of Medicine, Shandong University, 44#, Wenhua Xi Road, Jinan, Shandong, 250012, People's Republic of China.
Pan F; Department of Medical Psychology and Ethics, School of Basic Medical Medicine Sciences, Cheeloo College of Medicine, Shandong University, 44#, Wenhua Xi Road, Jinan, Shandong, 250012, People's Republic of China. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2023 Apr; Vol. 240 (4), pp. 837-851. Date of Electronic Publication: 2023 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Brain-Derived Neurotrophic Factor*/genetics
Brain-Derived Neurotrophic Factor*/metabolism
Receptor, Metabotropic Glutamate 5*/genetics
Receptor, Metabotropic Glutamate 5*/metabolism
Receptor, trkB*/genetics
Receptor, trkB*/metabolism
Stress Disorders, Post-Traumatic*/genetics
Stress Disorders, Post-Traumatic*/metabolism
Excitatory Amino Acid Transporter 2*/genetics
Excitatory Amino Acid Transporter 2*/metabolism
Animals ; Rats ; Hippocampus/metabolism ; Prefrontal Cortex/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interaction between a Novel Oligopeptide Fragment of the Human Neurotrophin Receptor TrkB Ectodomain D5 and the C-Terminal Fragment of Tetanus Neurotoxin.
Autorzy:
Candalija A; Molecular Biology Department, Institut de Neruociènces and Biochemistry, Medicine Faculty, Universitat Autònoma de Barcelona (UAB), 08193 Barcelona, Spain.
Scior T; Faculty of Chemical Sciences, BUAP, Puebla 72000, Mexico.
Rackwitz HR; Peptide Specialities Laboratory, Im Neuenheimer Feld, Univerisity Campus, 69120 Heidelberg, Germany.
Ruiz-Castelan JE; Faculty of Chemical Sciences, BUAP, Puebla 72000, Mexico.
Martinez-Laguna Y; Faculty of Chemical Sciences, BUAP, Puebla 72000, Mexico.
Aguilera J; Molecular Biology Department, Institut de Neruociènces and Biochemistry, Medicine Faculty, Universitat Autònoma de Barcelona (UAB), 08193 Barcelona, Spain.; Center for Biomedical Research Network on Neurodegenerative Diseases (CIBERNED), 08193 Cerdanyola del Vallès, Spain.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 30; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 30.
Typ publikacji:
Journal Article
MeSH Terms:
Membrane Glycoproteins/*chemistry
Metalloendopeptidases/*chemistry
Neuroprotective Agents/*chemistry
Oligopeptides/*chemistry
Receptor, trkB/*chemistry
Tetanus Toxin/*chemistry
Animals ; Crystallography, X-Ray ; Humans ; Membrane Glycoproteins/metabolism ; Membrane Glycoproteins/pharmacology ; Metalloendopeptidases/metabolism ; Metalloendopeptidases/pharmacology ; Neuroprotective Agents/metabolism ; Neuroprotective Agents/pharmacology ; Oligopeptides/metabolism ; Oligopeptides/pharmacology ; Protein Domains ; Rats ; Rats, Sprague-Dawley ; Receptor, trkB/metabolism ; Receptor, trkB/pharmacology ; Tetanus Toxin/metabolism ; Tetanus Toxin/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Central Stimulatory Effect of Kynurenic Acid on BDNF-TrkB Signaling and BER Enzymatic Activity in the Hippocampal CA1 Field in Sheep.
Autorzy:
Roszkowicz-Ostrowska K; The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.
Młotkowska P; The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.
Kowalczyk P; The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.
Marciniak E; The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.
Barszcz M; The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.
Misztal T; The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 21; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Kynurenic Acid*/pharmacology
Kynurenic Acid*/metabolism
Receptor, trkB*/genetics
Receptor, trkB*/metabolism
Animals ; Sheep ; Brain-Derived Neurotrophic Factor/genetics ; Brain-Derived Neurotrophic Factor/metabolism ; Hippocampus/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice.
Autorzy:
Zhou SB; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Xue M; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Liu W; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Chen YX; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Chen QY; Institute of Brain Research, Qingdao International Academician Park, Qingdao, Shandong, China.; CAS Key Laboratory of Brain Connectome and Manipulation, Interdisciplinary Center for Brain Information, The Brain Cognition and Brain Disease Institute, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences Shenzhen Institute of Advanced Technology, Shenzhen, China.
Lu JS; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China.; Institute of Brain Research, Qingdao International Academician Park, Qingdao, Shandong, China.
Wang J; Institute of Artificial Intelligence and Robotics, Xi'an Jiaotong University, Xi'an, China.
Ye K; Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.; Faculty of Life and Health Sciences, Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Li XH; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China. .; Institute of Brain Research, Qingdao International Academician Park, Qingdao, Shandong, China. .
Zhuo M; Center for Neuron and Disease, Frontier Institutes of Science and Technology, Xi'an Jiaotong University, Xi'an, China. .; Institute of Brain Research, Qingdao International Academician Park, Qingdao, Shandong, China. .; Oujiang Laboratory, Zhejiang Lab for Regenerative Medicine, Vision and Brain Health, Wenzhou, 325000, Zhejiang, China. .; Department of Physiology, Faculty of Medicine, University of Toronto, Medical Science Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada. .
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Źródło:
Molecular brain [Mol Brain] 2023 Jan 06; Vol. 16 (1), pp. 4. Date of Electronic Publication: 2023 Jan 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain-Derived Neurotrophic Factor*/pharmacology
Brain-Derived Neurotrophic Factor*/metabolism
Receptor, trkB*/metabolism
Mice ; Male ; Female ; Animals ; Gyrus Cinguli ; Long-Term Potentiation/physiology ; Hippocampus/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Receptor-Independent Anti-Ferroptotic Activity of TrkB Modulators.
Autorzy:
Jakaria M; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3052, Australia.
Belaidi AA; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3052, Australia.
Southon A; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3052, Australia.
Dent KA; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3052, Australia.
Lane DJR; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3052, Australia.
Bush AI; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3052, Australia.
Ayton S; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3052, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 19; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 19.
Typ publikacji:
Journal Article
MeSH Terms:
Brain-Derived Neurotrophic Factor*/metabolism
Receptor, trkB*/metabolism
Signal Transduction ; Neurons/metabolism ; Cell Survival
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antidepressive Effect of Natural Products and Their Derivatives Targeting BDNF-TrkB in Gut-Brain Axis.
Autorzy:
Liaqat H; Department of Animal Science, Biotechnical Faculty, University of Ljubljana, Groblje 3, 1230 Domzale, Slovenia.
Parveen A; College of Pharmacy, Gachon University, No. 191, Hambakmoero, Yeonsu-gu, Incheon 21936, Republic of Korea.
Kim SY; College of Pharmacy, Gachon University, No. 191, Hambakmoero, Yeonsu-gu, Incheon 21936, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 29; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Receptor, trkB*
Biological Products*/pharmacology
Animals ; Brain-Gut Axis ; Tropomyosin ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Brain-Derived Neurotrophic Factor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biphasic Response of Astrocytic Brain-Derived Neurotrophic Factor Expression following Corticosterone Stimulation.
Autorzy:
Tsimpolis A; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, 70013 Heraklion, Crete, Greece.
Kokkali M; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, 70013 Heraklion, Crete, Greece.
Logothetis A; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, 70013 Heraklion, Crete, Greece.
Kalafatakis K; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Health Sciences Education, Barts and the London School of Medicine and Dentistry (Malta Campus), Queen Mary University of London, VCT 2520 Victoria, Gozo, Malta.
Charalampopoulos I; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, 70013 Heraklion, Crete, Greece.
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Źródło:
Biomolecules [Biomolecules] 2022 Sep 18; Vol. 12 (9). Date of Electronic Publication: 2022 Sep 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain-Derived Neurotrophic Factor*/metabolism
Receptor, trkB*/genetics
Receptor, trkB*/metabolism
Astrocytes/metabolism ; Corticosterone/pharmacology ; Glucocorticoids/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Glucocorticoid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BDNF/TRKB axis provokes EMT progression to induce cell aggressiveness via crosstalk with cancer-associated fibroblasts in human parotid gland cancer.
Autorzy:
Moriwaki K; Department of Pharmacology, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki, Osaka, 569-8686, Japan. .
Wada M; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki, Osaka, 569-8686, Japan.
Kuwabara H; Department of Pathology, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki, Osaka, 569-8686, Japan.
Ayani Y; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki, Osaka, 569-8686, Japan.
Terada T; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki, Osaka, 569-8686, Japan.
Higashino M; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki, Osaka, 569-8686, Japan.
Kawata R; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki, Osaka, 569-8686, Japan.
Asahi M; Department of Pharmacology, Faculty of Medicine, Osaka Medical and Pharmaceutical University, 2-7, Daigaku-Machi, Takatsuki, Osaka, 569-8686, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 20; Vol. 12 (1), pp. 17553. Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain-Derived Neurotrophic Factor*/metabolism
Cancer-Associated Fibroblasts*/metabolism
Receptor, trkB*/metabolism
Salivary Gland Neoplasms*/metabolism
Salivary Gland Neoplasms*/pathology
Humans ; Cell Line, Tumor ; Culture Media, Conditioned ; Epithelial-Mesenchymal Transition ; Parotid Gland/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in Hyperammonemia.
Autorzy:
Arenas YM; Laboratory of Neurobiology, Centro Investigación Príncipe Felipe, 46012 Valencia, Spain.
Martínez-García M; Laboratory of Neurobiology, Centro Investigación Príncipe Felipe, 46012 Valencia, Spain.
Llansola M; Laboratory of Neurobiology, Centro Investigación Príncipe Felipe, 46012 Valencia, Spain.
Felipo V; Laboratory of Neurobiology, Centro Investigación Príncipe Felipe, 46012 Valencia, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 04; Vol. 23 (19). Date of Electronic Publication: 2022 Oct 04.
Typ publikacji:
Journal Article
MeSH Terms:
Brain-Derived Neurotrophic Factor*/metabolism
Hepatic Encephalopathy*
Hyperammonemia*/complications
Receptor, trkB*/metabolism
Symporters*/metabolism
Animals ; Cerebellum/metabolism ; Chlorides/metabolism ; Rats ; Rats, Wistar ; Receptors, GABA-A/metabolism ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Synaptic Transmission ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The First Dipeptide Mimetic of Neurotrofin-3: Design and Pharmacological Properties.
Autorzy:
Gudasheva TA; Zakusov Research Institute of Pharmacology, Moscow, Russia. .
Sazonova NM; Zakusov Research Institute of Pharmacology, Moscow, Russia.
Tarasiuk AV; Zakusov Research Institute of Pharmacology, Moscow, Russia.
Logvinov IO; Zakusov Research Institute of Pharmacology, Moscow, Russia.
Antipova TA; Zakusov Research Institute of Pharmacology, Moscow, Russia.
Nikiforov DM; Zakusov Research Institute of Pharmacology, Moscow, Russia.
Povarnina PY; Zakusov Research Institute of Pharmacology, Moscow, Russia.
Seredenin SB; Zakusov Research Institute of Pharmacology, Moscow, Russia.
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Źródło:
Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2022 Aug; Vol. 505 (1), pp. 160-165. Date of Electronic Publication: 2022 Aug 29.
Typ publikacji:
Journal Article
MeSH Terms:
Dipeptides*/chemistry
Dipeptides*/pharmacology
Receptor, trkB*
Animals ; Antidepressive Agents/chemistry ; Antidepressive Agents/pharmacology ; Biomimetic Materials ; Hippocampus ; Mice ; Nerve Growth Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BDNF Therapeutic Mechanisms in Neuropsychiatric Disorders.
Autorzy:
Bazzari AH; Faculty of Medicine, Arab American University, 13 Zababdeh, Jenin 240, Palestine.
Bazzari FH; Faculty of Pharmacy, Arab American University, 13 Zababdeh, Jenin 240, Palestine.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 29; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Brain-Derived Neurotrophic Factor*/metabolism
Receptor, trkB*/metabolism
Animals ; Brain/metabolism ; Mice ; Neurons/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Study on the mechanism of visual aging in cats' primary visual cortex based on BDNF-TrkB signal pathway.
Autorzy:
Tong C; College of Food and Bioengineering, Wuhu Institute of Technology, Wuhu, 241003, People's Republic of China.
Cao S; Center of Reproductive Medicine, Huai'an Maternal and Child Health Care Hospital, Huai'an, 223002, People's Republic of China. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jun 22; Vol. 12 (1), pp. 10576. Date of Electronic Publication: 2022 Jun 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain-Derived Neurotrophic Factor*/metabolism
Receptor, trkB*/metabolism
Aging/metabolism ; Animals ; Cats ; Primary Visual Cortex ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BDNF and TrKB expression levels in patients with endometriosis and their associations with dysmenorrhoea.
Autorzy:
Wang S; Department of Minimally Invasive Gynecologic Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100006, China.
Duan H; Department of Minimally Invasive Gynecologic Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100006, China. .
Li B; Department of Minimally Invasive Gynecologic Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100006, China.
Hong W; Department of Minimally Invasive Gynecologic Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100006, China.
Li X; Department of Minimally Invasive Gynecologic Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100006, China.
Wang Y; Department of Minimally Invasive Gynecologic Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100006, China.
Guo ZC; Department of Minimally Invasive Gynecologic Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100006, China.
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Źródło:
Journal of ovarian research [J Ovarian Res] 2022 Mar 17; Vol. 15 (1), pp. 35. Date of Electronic Publication: 2022 Mar 17.
Typ publikacji:
Journal Article
MeSH Terms:
Brain-Derived Neurotrophic Factor*/metabolism
Dysmenorrhea*/etiology
Dysmenorrhea*/metabolism
Endometriosis*/complications
Endometriosis*/metabolism
Membrane Glycoproteins*/metabolism
Receptor, trkB*/metabolism
Endometrium/metabolism ; Female ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BDNF-TrkB signaling-mediated upregulation of Narp is involved in the antidepressant-like effects of (2R,6R)-hydroxynorketamine in a chronic restraint stress mouse model.
Autorzy:
Ju L; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yang J; Department of Anesthesiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China.
Zhu T; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Liu P; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yang J; Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. .
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Źródło:
BMC psychiatry [BMC Psychiatry] 2022 Mar 15; Vol. 22 (1), pp. 182. Date of Electronic Publication: 2022 Mar 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antidepressive Agents*/pharmacology
Brain-Derived Neurotrophic Factor*/metabolism
C-Reactive Protein*/metabolism
Depression*/drug therapy
Ketamine*/analogs & derivatives
Ketamine*/pharmacology
Nerve Tissue Proteins*/metabolism
Receptor, trkB*/metabolism
Animals ; Disease Models, Animal ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mulberry fruit improves memory in scopolamine-treated mice: role of cholinergic function, antioxidant system, and TrkB/Akt signaling.
Autorzy:
Shin SK; Department of Food and Nutrition, Chungnam National University, Daejeon, Republic of Korea.; Ohjeong Agricultural Products Inspection Office, Division of Food and Drug Research, Institute of Health and Environment in Daejeon, Daejeon, Republic of Korea.
Yoo JM; Korean Medicine-Application Center, Korea Institute of Oriental Medicine, Daegu, Republic of Korea.; Korean Medicine R&D Team 1, National Institute for Korean Medicine Development, Gyeongsan, Republic of Korea.
Li FY; Department of Food and Nutrition, Chungnam National University, Daejeon, Republic of Korea.
Baek SY; Department of Food and Nutrition, Chungnam National University, Daejeon, Republic of Korea.
Kim MR; Department of Food and Nutrition, Chungnam National University, Daejeon, Republic of Korea.
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Źródło:
Nutritional neuroscience [Nutr Neurosci] 2021 Dec; Vol. 24 (12), pp. 940-950. Date of Electronic Publication: 2019 Dec 02.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*
Cholinergic Agents*
Morus*
Memory Disorders/*drug therapy
Plant Extracts/*administration & dosage
Receptor, trkB/*physiology
Animals ; Apoptosis/drug effects ; Brain-Derived Neurotrophic Factor/genetics ; Cell Line ; Fruit/chemistry ; Glutamic Acid/pharmacology ; Hippocampus/cytology ; Male ; Memory Disorders/chemically induced ; Mice ; Mice, Inbred ICR ; Neurons/drug effects ; Neurons/physiology ; Neuroprotective Agents ; Oxidative Stress/drug effects ; Phytotherapy ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/physiology ; Receptor, trkB/antagonists & inhibitors ; Scopolamine/pharmacology ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
TrkB/C-induced HOXC6 activation enhances the ADAM8-mediated metastasis of chemoresistant colon cancer cells.
Autorzy:
Park GB; Department of Biochemistry, Kosin University College of Medicine, Busan 49267, Republic of Korea.
Choi S; Department of Internal Medicine, Division of Respirology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul 01757, Republic of Korea.
Yoon YS; Department of Thoracic and Cardiovascular Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan 47392, Republic of Korea.
Kim D; Department of Anatomy, Inje University College of Medicine, Busan 47392, Republic of Korea.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2021 Jun; Vol. 23 (6). Date of Electronic Publication: 2021 Apr 13.
Typ publikacji:
Journal Article
MeSH Terms:
ADAM Proteins/*metabolism
Colonic Neoplasms/*metabolism
Genes, Homeobox/*drug effects
Homeodomain Proteins/*metabolism
Membrane Glycoproteins/*metabolism
Membrane Proteins/*metabolism
Receptor, trkB/*metabolism
Receptor, trkC/*metabolism
ADAM Proteins/genetics ; ADAM10 Protein ; ADAM17 Protein ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Movement/drug effects ; Colonic Neoplasms/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Homeodomain Proteins/genetics ; Humans ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/pharmacology ; Membrane Proteins/genetics ; Receptor, trkB/genetics ; Receptor, trkB/pharmacology ; Receptor, trkC/genetics ; Receptor, trkC/pharmacology ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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