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Tytuł:
Trace Metal Impurities Effects on the Formation of [ Cu]Cu-ATSM).
Autorzy:
Shinada M; Faculty of Science, Toho University, Funabashi 274-8510, Japan.; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
Suzuki H; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Hanyu M; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Igarashi C; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
Matsumoto H; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
Takahashi M; Faculty of Science, Toho University, Funabashi 274-8510, Japan.; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Hihara F; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Tachibana T; Faculty of Science, Toho University, Funabashi 274-8510, Japan.; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Sogawa C; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Zhang MR; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Higashi T; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Sato H; Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
Kurihara H; Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
Yoshii Y; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
Doi Y; Faculty of Science, Toho University, Funabashi 274-8510, Japan.
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Źródło:
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Dec 21; Vol. 17 (1). Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An In Vivo Dual-Observation Method to Monitor Tumor Mass and Tumor-Surface Blood Vessels for Developing Anti-Angiogenesis Agents against Submillimeter Tumors.
Autorzy:
Tachibana T; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.; Faculty of Science, Toho University, Chiba 274-8510, Japan.
Oyama TG; Foundational Quantum Technology Research Directorate, National Institutes for Quantum Science and Technology (QST), Gunma 370-1292, Japan.
Yoshii Y; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.; Visible Cancer Drug Research Unit, National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.
Hihara F; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.
Igarashi C; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.
Shinada M; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.; Faculty of Science, Toho University, Chiba 274-8510, Japan.
Matsumoto H; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.
Higashi T; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), Chiba 263-8555, Japan.
Kishimoto T; Faculty of Science, Toho University, Chiba 274-8510, Japan.
Taguchi M; Foundational Quantum Technology Research Directorate, National Institutes for Quantum Science and Technology (QST), Gunma 370-1292, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 07; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Angiogenesis Inhibitors*/pharmacology
Angiogenesis Inhibitors*/therapeutic use
Neoplasms*/diagnostic imaging
Neoplasms*/drug therapy
Neoplasms*/pathology
Humans ; Mice ; Animals ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Pathologic/diagnosis ; Green Fluorescent Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Process to Remove the Size Variants Contained in the Antibody-Chelator Complex PCTA-NCAB001 for Radiolabeling with Copper-64.
Autorzy:
Yoshii Y; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Diagnostic Radiology, Kanagawa Cancer Center, Yokohama 241-8515, Japan.
Matsumoto H; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Diagnostic Radiology, Kanagawa Cancer Center, Yokohama 241-8515, Japan.
Igarashi C; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Diagnostic Radiology, Kanagawa Cancer Center, Yokohama 241-8515, Japan.
Tachibana T; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Biology, Graduate School of Science, Toho University, Chiba 274-8510, Japan.
Hihara F; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Shinada M; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Chemistry, Graduate School of Science, Toho University, Chiba 274-8510, Japan.
Waki A; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Yoshida S; Department of Research, NanoCarrier Co., Ltd., Tokyo 104-0031, Japan.
Naito K; Department of Research, NanoCarrier Co., Ltd., Tokyo 104-0031, Japan.
Ito K; Department of Diagnostic Radiology, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Higashi T; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Kurihara H; Department of Diagnostic Radiology, Kanagawa Cancer Center, Yokohama 241-8515, Japan.
Ueno M; Department of Gastroenterology, Kanagawa Cancer Center, Yokohama 241-8515, Japan.
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Źródło:
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Sep 22; Vol. 16 (10). Date of Electronic Publication: 2023 Sep 22.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preclinical Safety Evaluation of Intraperitoneally Administered Cu-Conjugated Anti-EGFR Antibody NCAB001 for the Early Diagnosis of Pancreatic Cancer Using PET.
Autorzy:
Matsumoto H; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Diagnostic Radiology, Kanagawa Cancer Center, Yokohama 241-8515, Japan.
Igarashi C; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Tachibana T; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Hihara F; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Shinada M; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Chemistry, Graduate School of Science, Toho University, Chiba 274-8510, Japan.
Waki A; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Yoshida S; Department of Research, NanoCarrier Co., Ltd., Tokyo 104-0031, Japan.
Naito K; Department of Research, NanoCarrier Co., Ltd., Tokyo 104-0031, Japan.
Kurihara H; Department of Diagnostic Radiology, Kanagawa Cancer Center, Yokohama 241-8515, Japan.
Ueno M; Department of Gastroenterology, Kanagawa Cancer Center, Yokohama 241-8515, Japan.
Ito K; Department of Diagnostic Radiology, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Higashi T; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Yoshii Y; Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Diagnostic Radiology, Kanagawa Cancer Center, Yokohama 241-8515, Japan.
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Źródło:
Pharmaceutics [Pharmaceutics] 2022 Sep 12; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 12.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Vitro Tumor Cell-Binding Assay to Select High-Binding Antibody and Predict Therapy Response for Personalized Cu-Intraperitoneal Radioimmunotherapy against Peritoneal Dissemination of Pancreatic Cancer: A Feasibility Study.
Autorzy:
Hihara F; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Matsumoto H; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Diagnostic Radiology, Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
Yoshimoto M; Division of Functional Imaging, National Cancer Center Hospital East, Chiba 277-8577, Japan.
Masuko T; School of Pharmacy, Kindai University, Osaka 577-8502, Japan.
Endo Y; School of Pharmacy, Kindai University, Osaka 577-8502, Japan.
Igarashi C; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Tachibana T; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Shinada M; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Faculty of Science, Toho University, Chiba 274-8510, Japan.
Zhang MR; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Kurosawa G; International Center for Cell and Gene Therapy, Fujita Health University, Aichi 470-1192, Japan.
Sugyo A; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Tsuji AB; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Higashi T; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.
Kurihara H; Department of Diagnostic Radiology, Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
Ueno M; Department of Gastroenterology, Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
Yoshii Y; Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan.; Department of Diagnostic Radiology, Kanagawa Cancer Center, Kanagawa 241-8515, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 22; Vol. 23 (10). Date of Electronic Publication: 2022 May 22.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/radiotherapy
Radioimmunotherapy*
Animals ; Cell Line, Tumor ; Disease Models, Animal ; Feasibility Studies ; Humans ; Mice ; Pancreatic Neoplasms
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluation of Aminopolycarboxylate Chelators for Whole-Body Clearance of Free Ac: A Feasibility Study to Reduce Unexpected Radiation Exposure during Targeted Alpha Therapy.
Autorzy:
Yoshimoto M; Division of Functional Imaging, National Cancer Center Hospital East, Kashiwa 277-8577, Japan.
Yoshii Y; National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan.
Matsumoto H; National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan.
Shinada M; National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan.; Faculty of Science, Toho University, Funabashi 274-8510, Japan.
Takahashi M; National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan.; Faculty of Science, Toho University, Funabashi 274-8510, Japan.
Igarashi C; National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan.
Hihara F; National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan.
Tachibana T; National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan.
Doi A; Division of Functional Imaging, National Cancer Center Hospital East, Kashiwa 277-8577, Japan.
Higashi T; National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan.
Fujii H; Division of Functional Imaging, National Cancer Center Hospital East, Kashiwa 277-8577, Japan.
Washiyama K; Advanced Clinical Research Center, Fukushima Medical University, Fukushima 960-1295, Japan.
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Źródło:
Pharmaceutics [Pharmaceutics] 2021 Oct 16; Vol. 13 (10). Date of Electronic Publication: 2021 Oct 16.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Aberrant expression of the COX2/PGE2 axis is induced by activation of the RAF/MEK/ERK pathway in BRAFV595E canine urothelial carcinoma.
Autorzy:
Yoshitake, R.
Saeki, K.
Eto, S.
Shinada, M.
Nakano, R.
Sugiya, H.
Endo, Y.
Fujita, N.
Nishimura, R.
Nakagawa, T.
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Temat:
DINOPROSTONE
TRANSITIONAL cell carcinoma
URINARY organ cancer treatment
DRUG use testing
PHARMACOLOGY
Źródło:
Scientific Reports; 5/8/2020, Vol. 10 Issue 1, p1-13, 13p
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phase I/II Clinical Trial of the Anti-Podoplanin Monoclonal Antibody Therapy in Dogs with Malignant Melanoma.
Autorzy:
Kamoto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Shinada M; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Kato D; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Yoshimoto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Ikeda N; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Tsuboi M; Veterinary Medical Center, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Yoshitake R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Eto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Hashimoto Y; Veterinary Medical Center, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Takahashi Y; Veterinary Medical Center, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Chambers J; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Uchida K; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Kaneko MK; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Fujita N; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Nishimura R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Kato Y; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.; New Industry Creation Hatchery Center, Tohoku University, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Nakagawa T; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
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Źródło:
Cells [Cells] 2020 Nov 23; Vol. 9 (11). Date of Electronic Publication: 2020 Nov 23.
Typ publikacji:
Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal/*therapeutic use
Melanoma/*drug therapy
Animals ; Antibodies, Monoclonal/pharmacology ; Dogs ; Melanoma/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Author Correction: Aberrant expression of the COX2/PGE 2 axis is induced by activation of the RAF/MEK/ERK pathway in BRAF canine urothelial carcinoma.
Autorzy:
Yoshitake R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Saeki K; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan. .
Eto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Shinada M; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Nakano R; Laboratory of Veterinary Biochemistry, Department of Veterinary Medicine, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan.
Sugiya H; Laboratory of Veterinary Biochemistry, Department of Veterinary Medicine, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan.
Endo Y; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Fujita N; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Nishimura R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Nakagawa T; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 Oct 28; Vol. 10 (1), pp. 18820. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Aberrant expression of the COX2/PGE 2 axis is induced by activation of the RAF/MEK/ERK pathway in BRAF canine urothelial carcinoma.
Autorzy:
Yoshitake R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Saeki K; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan. .
Eto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Shinada M; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Nakano R; Laboratory of Veterinary Biochemistry, Department of Veterinary Medicine, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan.
Sugiya H; Laboratory of Veterinary Biochemistry, Department of Veterinary Medicine, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan.
Endo Y; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Fujita N; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Nishimura R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
Nakagawa T; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
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Źródło:
Scientific reports [Sci Rep] 2020 May 08; Vol. 10 (1), pp. 7826. Date of Electronic Publication: 2020 May 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma/*genetics
Cyclooxygenase 2/*genetics
Dinoprostone/*genetics
Dog Diseases/*genetics
Proto-Oncogene Proteins B-raf/*genetics
Animals ; Carcinoma/pathology ; Dog Diseases/pathology ; Dogs ; Gene Expression Regulation, Neoplastic/genetics ; MAP Kinase Kinase Kinases/genetics ; MAP Kinase Signaling System/genetics ; Signal Transduction ; Urothelium/metabolism ; Urothelium/pathology ; raf Kinases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
PDPN Is Expressed in Various Types of Canine Tumors and Its Silencing Induces Apoptosis and Cell Cycle Arrest in Canine Malignant Melanoma.
Autorzy:
Shinada M; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Kato D; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Kamoto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Yoshimoto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Tsuboi M; Veterinary Medical Center, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Yoshitake R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Eto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Ikeda N; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Saeki K; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Hashimoto Y; Veterinary Medical Center, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Takahashi Y; Veterinary Medical Center, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Chambers J; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Uchida K; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Kaneko MK; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Fujita N; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Nishimura R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Kato Y; Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.; New Industry Creation Hatchery Center, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Nakagawa T; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
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Źródło:
Cells [Cells] 2020 May 05; Vol. 9 (5). Date of Electronic Publication: 2020 May 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Cell Cycle Checkpoints*
Gene Silencing*
Dogs/*metabolism
Melanoma/*metabolism
Melanoma/*veterinary
Membrane Glycoproteins/*metabolism
Animals ; Cell Line, Tumor ; Cell Survival ; G2 Phase ; Melanoma/pathology ; Mitosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anti-tumor effects of the histone deacetylase inhibitor vorinostat on canine urothelial carcinoma cells.
Autorzy:
Eto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Saeki K; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Yoshitake R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Yoshimoto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Shinada M; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Ikeda N; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Kamoto S; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Tanaka Y; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Kato D; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Maeda S; Laboratory of Veterinary Clinical Pathology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Tsuboi M; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Chambers J; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Uchida K; Laboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Nishimura R; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Nakagawa T; Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
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Źródło:
PloS one [PLoS One] 2019 Jun 17; Vol. 14 (6), pp. e0218382. Date of Electronic Publication: 2019 Jun 17 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Transitional Cell/*drug therapy
Urinary Bladder Neoplasms/*drug therapy
Urothelium/*pathology
Vorinostat/*pharmacology
Acetylation ; Animals ; Antineoplastic Agents/pharmacology ; Carcinoma, Transitional Cell/mortality ; Carcinoma, Transitional Cell/pathology ; Carcinoma, Transitional Cell/veterinary ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dogs ; G1 Phase Cell Cycle Checkpoints/drug effects ; Histone Deacetylase Inhibitors/pharmacology ; Prognosis ; Survival Analysis ; Urinary Bladder Neoplasms/mortality ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/veterinary ; Vorinostat/therapeutic use
Czasopismo naukowe
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Tytuł:
Discovery of novel polysubstituted N-alkyl acridone analogues as histone deacetylase isoform-selective inhibitors for cancer therapy.
Autorzy:
Wang, Ze (AUTHOR)
Zhao, Li (AUTHOR)
Zhang, Bo (AUTHOR)
Feng, Jiahe (AUTHOR)
Wang, Yule (AUTHOR)
Zhang, Bin (AUTHOR)
Jin, Haixiao (AUTHOR)
Ding, Lijian (AUTHOR)
Wang, Ning (AUTHOR)
He, Shan (AUTHOR)
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Źródło:
Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-15. 15p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 875

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