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Wyświetlanie 1-20 z 715
Tytuł:
Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.
Autorzy:
Wirchnianski AS; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America.
Nyakatura EK; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Herbert AS; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.; The Geneva Foundation, Tacoma, Washington, United States of America.
Kuehne AI; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Abbasi SA; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.; The Geneva Foundation, Tacoma, Washington, United States of America.
Florez C; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.; The Geneva Foundation, Tacoma, Washington, United States of America.
Storm N; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America.
McKay LGA; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Dailey L; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Kuang E; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.
Abelson DM; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America.
Chakraborti S; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Holtsberg FW; Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America.
Shulenin S; Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America.
Bornholdt ZA; Mapp Biopharmaceutical Inc., San Diego, California, United States of America.
Aman MJ; Integrated BioTherapeutics, Inc., Rockville, Maryland, United States of America.
Honko AN; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Griffiths A; Department of Virology, Immunology, and Microbiology; and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Dye JM; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America.
Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Apr 11; Vol. 20 (4), pp. e1012134. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Bispecific*/immunology
Antibodies, Bispecific*/pharmacology
Antibodies, Bispecific*/therapeutic use
Ebolavirus*/immunology
Hemorrhagic Fever, Ebola*/immunology
Hemorrhagic Fever, Ebola*/prevention & control
Hemorrhagic Fever, Ebola*/virology
Antibodies, Viral*/immunology
Animals ; Mice ; Humans ; Filoviridae/immunology ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/therapeutic use ; Antibodies, Monoclonal/immunology ; Female ; Mice, Inbred BALB C ; Filoviridae Infections/immunology ; Filoviridae Infections/therapy ; Filoviridae Infections/prevention & control
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrier.
Autorzy:
Thomas, Joanna R. (AUTHOR)
Frye, William J. E. (AUTHOR)
Robey, Robert W. (AUTHOR)
Warner, Andrew C. (AUTHOR)
Butcher, Donna (AUTHOR)
Matta, Jennifer L. (AUTHOR)
Morgan, Tamara C. (AUTHOR)
Edmondson, Elijah F. (AUTHOR)
Salazar, Paula B. (AUTHOR)
Ambudkar, Suresh V. (AUTHOR)
Gottesman, Michael M. (AUTHOR)
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Źródło:
Fluids & Barriers of the CNS. 3/15/2024, Vol. 21 Issue 1, p1-12. 12p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins.
Autorzy:
Quiroz JA; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Malonis RJ; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Thackray LB; Department of Medicine, Washington University in St. Louis, School of Medicine, St. Louis, Missouri, United States of America.
Cohen CA; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America.
Pallesen J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Jangra RK; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Brown RS; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Hofmann D; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Holtsberg FW; Integrated Biotherapeutics Inc., Rockville, Maryland, United States of America.
Shulenin S; Integrated Biotherapeutics Inc., Rockville, Maryland, United States of America.
Nyakatura EK; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Durnell LA; Department of Medicine, Washington University in St. Louis, School of Medicine, St. Louis, Missouri, United States of America.
Rayannavar V; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Daily JP; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Aman MJ; Integrated Biotherapeutics Inc., Rockville, Maryland, United States of America.
Dye JM; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America.
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Diamond MS; Department of Medicine, Washington University in St. Louis, School of Medicine, St. Louis, Missouri, United States of America.; Department of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, Missouri, United States of America.; Department of Pathology & Immunology, Washington University in St. Louis, School of Medicine, St. Louis, Missouri, United States of America.
Kielian M; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.
Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2019 Nov 07; Vol. 15 (11), pp. e1008061. Date of Electronic Publication: 2019 Nov 07 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Antibodies, Monoclonal/*immunology
Antibodies, Viral/*immunology
Chikungunya Fever/*immunology
Chikungunya virus/*immunology
Epitopes/*immunology
Glycoproteins/*immunology
Viral Envelope Proteins/*immunology
Adult ; Animals ; Antibodies, Neutralizing/immunology ; Chikungunya Fever/virology ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Inbred ICR
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Descriptive and Functional Genomics in Neonatal Respiratory Distress Syndrome: From Lung Development to Targeted Therapies.
Autorzy:
Anciuc-Crauciuc, Mădălina (AUTHOR)
Cucerea, Manuela Camelia (AUTHOR)
Tripon, Florin (AUTHOR)
Crauciuc, George-Andrei (AUTHOR)
Bănescu, Claudia Violeta (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Jan2024, Vol. 25 Issue 1, p649. 23p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High-Avidity Anti-Filovirus IgG Elicited Using Protein Subunit Vaccines Does Not Correlate with Protection.
Autorzy:
Williams, Caitlin A. (AUTHOR)
Wong, Teri Ann S. (AUTHOR)
Lieberman, Michael M. (AUTHOR)
Yalley-Ogunro, Jake (AUTHOR)
Cabus, Mehtap (AUTHOR)
Nezami, Sara (AUTHOR)
Paz, Fabian (AUTHOR)
Andersen, Hanne (AUTHOR)
Geisbert, Thomas W. (AUTHOR)
Lehrer, Axel T. (AUTHOR)
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Źródło:
Immuno. Dec2023, Vol. 3 Issue 4, p358-374. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses.
Autorzy:
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Nyakatura EK; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
Howell KA; Integrated Biotherapeutics Inc., Gaithersburg, MD 20878, USA.
Holtsberg FW; Integrated Biotherapeutics Inc., Gaithersburg, MD 20878, USA.
Bakken RR; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
Mittler E; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Christin JR; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Shulenin S; Integrated Biotherapeutics Inc., Gaithersburg, MD 20878, USA.
Jangra RK; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Bharrhan S; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Kuehne AI; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
Bornholdt ZA; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 10550, USA.
Flyak AI; Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN 37235, USA.
Saphire EO; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 10550, USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 10550, USA.
Crowe JE Jr; Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN 37235, USA. .; Department of Pediatrics, Vanderbilt University, Nashville, TN 37232, USA.; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232, USA.
Aman MJ; Integrated Biotherapeutics Inc., Gaithersburg, MD 20878, USA. .
Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA. .
Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA. .
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. .
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Źródło:
Science (New York, N.Y.) [Science] 2016 Oct 21; Vol. 354 (6310), pp. 350-354. Date of Electronic Publication: 2016 Sep 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Bispecific/*immunology
Antibodies, Neutralizing/*immunology
Antibodies, Viral/*immunology
Carrier Proteins/*immunology
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*prevention & control
Membrane Glycoproteins/*immunology
Receptors, Virus/*immunology
Viral Envelope Proteins/*immunology
Animals ; Antibodies, Monoclonal/immunology ; Binding Sites/immunology ; Cell Line, Tumor ; Endosomes/virology ; Hemorrhagic Fever, Ebola/therapy ; Humans ; Immunotherapy/methods ; Intracellular Signaling Peptides and Proteins ; Mice ; Mice, Inbred BALB C ; Niemann-Pick C1 Protein ; Virus Internalization
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Correction: Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs.
Autorzy:
Adhikari RP
Kort T
Shulenin S
Kanipakala T
Ganjbaksh N
Roghmann MC
Holtsberg FW
Aman MJ
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Źródło:
PloS one [PLoS One] 2015 Nov 16; Vol. 10 (11), pp. e0143493. Date of Electronic Publication: 2015 Nov 16 (Print Publication: 2015).
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Correction: Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs.
Autorzy:
Fusco ML
Hashiguchi T
Cassan R
Biggins JE
Murin CD
Warfield KL
Li S
Holtsberg FW
Shulenin S
Vu H
Olinger GG
Kim DH
Whaley KJ
Zeitlin L
Ward AB
Nykiforuk C
Aman MJ
Berry JD
Saphire EO
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Źródło:
PLoS pathogens [PLoS Pathog] 2015 Oct 09; Vol. 11 (10), pp. e1005212. Date of Electronic Publication: 2015 Oct 09 (Print Publication: 2015).
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs.
Autorzy:
Adhikari RP; Integrated Biotherapeutics Inc., Gaithersburg, Maryland, United States of America.
Kort T; Integrated Biotherapeutics Inc., Gaithersburg, Maryland, United States of America.
Shulenin S; Integrated Biotherapeutics Inc., Gaithersburg, Maryland, United States of America.
Kanipakala T; Integrated Biotherapeutics Inc., Gaithersburg, Maryland, United States of America.
Ganjbaksh N; Integrated Biotherapeutics Inc., Gaithersburg, Maryland, United States of America.
Roghmann MC; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; VA Maryland Health Care System, Baltimore, Maryland, United States of America.
Holtsberg FW; Integrated Biotherapeutics Inc., Gaithersburg, Maryland, United States of America.
Aman MJ; Integrated Biotherapeutics Inc., Gaithersburg, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Sep 14; Vol. 10 (9), pp. e0137874. Date of Electronic Publication: 2015 Sep 14 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Bacterial Proteins/*immunology
Leukocidins/*immunology
Staphylococcal Vaccines/*immunology
Staphylococcus aureus/*immunology
Adult ; Animals ; Antibodies/immunology ; Bacterial Proteins/genetics ; Bacterial Proteins/toxicity ; Bacterial Toxins/genetics ; Bacterial Toxins/immunology ; Bacterial Toxins/toxicity ; Cross Reactions ; Cytotoxicity Tests, Immunologic ; Exotoxins/genetics ; Exotoxins/immunology ; Exotoxins/toxicity ; Female ; Humans ; Leukocidins/genetics ; Leukocidins/toxicity ; Mice, Inbred BALB C ; Mice, Inbred ICR ; Neutralization Tests ; Rabbits ; Staphylococcal Infections/microbiology ; Staphylococcal Vaccines/pharmacology ; Staphylococcus aureus/pathogenicity ; Vaccines, Attenuated/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs.
Autorzy:
Fusco ML; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America.
Hashiguchi T; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America; Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Cassan R; Emergent BioSolutions (formerly Cangene Corporation), Winnipeg, Manitoba, Canada.
Biggins JE; Division of Virology, United States Army Research Institute for Infectious Disease, Ft. Detrick, Maryland, United States of America; Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America.
Murin CD; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Warfield KL; Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America.
Li S; Department of Medicine, University of California San Diego, La Jolla, California, United States of America.
Holtsberg FW; Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America.
Shulenin S; Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America.
Vu H; Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America.
Olinger GG; Division of Virology, United States Army Research Institute for Infectious Disease, Ft. Detrick, Maryland, United States of America; Integrated Research Facility, NIAID, National Institutes of Health, Frederick, Maryland, United States of America.
Kim DH; Mapp Biopharmaceutical, Inc., San Diego, California, United States of America.
Whaley KJ; Mapp Biopharmaceutical, Inc., San Diego, California, United States of America.
Zeitlin L; Mapp Biopharmaceutical, Inc., San Diego, California, United States of America.
Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Nykiforuk C; Emergent BioSolutions (formerly Cangene Corporation), Winnipeg, Manitoba, Canada.
Aman MJ; Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America.
Berry JD
Saphire EO; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2015 Jun 26; Vol. 11 (6), pp. e1005016. Date of Electronic Publication: 2015 Jun 26 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunization*
Antibodies, Monoclonal/*immunology
Antibodies, Monoclonal/*pharmacology
Hemorrhagic Fever, Ebola/*immunology
Marburg Virus Disease/*prevention & control
Marburgvirus/*immunology
Animals ; Antibodies, Viral/immunology ; Cross Reactions/immunology ; Ebolavirus/immunology ; Female ; Male ; Marburg Virus Disease/immunology ; Mice, Inbred BALB C
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 715

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