Temat: "4-Nitroquinoline-1-oxide" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Fat and exposure to 4-nitroquinoline-1-oxide causes histologic and inflammatory changes in murine livers.
Autorzy:: Pitstick LD; Department of Biochemistry and Molecular Genetics, College of Graduate Studies, Midwestern University, Downers Grove, IL, United States of America.
Goral J; Department of Anatomy, College of Graduate Studies, Midwestern University, Downers Grove, IL, United States of America.
Schmelter RA; Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, IL, United States of America.
Fuja CM; Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, IL, United States of America.
Ciancio MJ; Department of Biomedical Sciences, College of Graduate Studies, Midwestern University, Downers Grove, IL, United States of America.
Pytynia M; Department of Biomedical Sciences, College of Graduate Studies, Midwestern University, Downers Grove, IL, United States of America.
Meyer A; Department of Anatomy, College of Graduate Studies, Midwestern University, Downers Grove, IL, United States of America.
Green JM; Department of Biochemistry and Molecular Genetics, College of Graduate Studies, Midwestern University, Downers Grove, IL, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 May 31; Vol. 17 (5), pp. e0268891. Date of Electronic Publication: 2022 May 31 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: 4-Nitroquinoline-1-oxide*/toxicity
Dietary Fats*
Animals ; Fibrosis ; Liver ; Male ; Mice ; Mice, Inbred C57BL ; Triglycerides

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Skocz do pozycji: 2.

Tytuł:: GPR68 limits the severity of chemical-induced oral epithelial dysplasia.
Autorzy:: Shore D; Marshall University School of Pharmacy, Huntington, WV, USA.
Griggs N; Marshall University School of Pharmacy, Huntington, WV, USA.
Graffeo V; Marshall University Joan C. Edwards School of Medicine, Huntington, WV, USA.
Amin ARMR; Marshall University School of Pharmacy, Huntington, WV, USA.
Zha XM; University of Missouri-Kansas City School of Pharmacy, Kansas City, MO, USA.
Xu Y; Indiana University School of Medicine, Indianapolis, IN, USA.
McAleer JP; Marshall University School of Pharmacy, Huntington, WV, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jan 07; Vol. 13 (1), pp. 353. Date of Electronic Publication: 2023 Jan 07.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Carcinoma, Squamous Cell*/pathology
Head and Neck Neoplasms*/chemically induced
Head and Neck Neoplasms*/genetics
Male ; Mice ; Animals ; Squamous Cell Carcinoma of Head and Neck ; Carcinogenesis/pathology ; 4-Nitroquinoline-1-oxide/toxicity ; Cell Transformation, Neoplastic ; Hyperplasia ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism ; Tumor Microenvironment

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Skocz do pozycji: 3.

Tytuł:: Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy.
Autorzy:: Yin P; Beijing Institute of Dental Research, Beijing Stomatological Hospital & School of Stomatology, Capital Medical University, 4 Tiantanxili, Dongcheng District, Beijing 100050, China.; Department of Periodontology, Tianjin Stomatological Hospital, 75 Dagu Road, Heping District, Tianjin 300041, China.
Chen J; Beijing Institute of Dental Research, Beijing Stomatological Hospital & School of Stomatology, Capital Medical University, 4 Tiantanxili, Dongcheng District, Beijing 100050, China.
Wu Y; Beijing Institute of Dental Research, Beijing Stomatological Hospital & School of Stomatology, Capital Medical University, 4 Tiantanxili, Dongcheng District, Beijing 100050, China.
Gao F; Beijing Institute of Dental Research, Beijing Stomatological Hospital & School of Stomatology, Capital Medical University, 4 Tiantanxili, Dongcheng District, Beijing 100050, China.
Wen J; Beijing Institute of Dental Research, Beijing Stomatological Hospital & School of Stomatology, Capital Medical University, 4 Tiantanxili, Dongcheng District, Beijing 100050, China.
Zhang W; Beijing Institute of Dental Research, Beijing Stomatological Hospital & School of Stomatology, Capital Medical University, 4 Tiantanxili, Dongcheng District, Beijing 100050, China.
Su Y; Beijing Institute of Dental Research, Beijing Stomatological Hospital & School of Stomatology, Capital Medical University, 4 Tiantanxili, Dongcheng District, Beijing 100050, China.
Zhang X; Beijing Institute of Dental Research, Beijing Stomatological Hospital & School of Stomatology, Capital Medical University, 4 Tiantanxili, Dongcheng District, Beijing 100050, China.; Pokaż więcej
Źródło:: Analytical cellular pathology (Amsterdam) [Anal Cell Pathol (Amst)] 2022 Oct 05; Vol. 2022, pp. 3770715. Date of Electronic Publication: 2022 Oct 05 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Squamous Cell*/chemically induced
Carcinoma, Squamous Cell*/genetics
Carcinoma, Squamous Cell*/prevention & control
Mouth Neoplasms*/pathology
4-Nitroquinoline-1-oxide/toxicity ; Animals ; Autophagy ; Carcinogenesis/pathology ; Chemoprevention ; Disease Models, Animal ; Humans ; Matrix Metalloproteinase 9 ; Mice ; Proto-Oncogene Proteins c-akt ; Signal Transduction ; Tongue/pathology ; rhoC GTP-Binding Protein

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Skocz do pozycji: 4.

Tytuł:: Genotoxicity of 12 Mycotoxins by the SOS/umu Test: Comparison of Liver and Kidney S9 Fraction.
Autorzy:: Alonso-Jauregui M; MITOX Research Group, Department of Pharmacology and Toxicology, School of Pharmacy and Nutrition, Universidad de Navarra, 31008 Pamplona, Spain.
González-Peñas E; MITOX Research Group, Department of Pharmaceutical Technology and Chemistry, School of Pharmacy and Nutrition, Universidad de Navarra, 31008 Pamplona, Spain.
López de Cerain A; MITOX Research Group, Department of Pharmacology and Toxicology, School of Pharmacy and Nutrition, Universidad de Navarra, 31008 Pamplona, Spain.
Vettorazzi A; MITOX Research Group, Department of Pharmacology and Toxicology, School of Pharmacy and Nutrition, Universidad de Navarra, 31008 Pamplona, Spain.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2022 Jun 10; Vol. 14 (6). Date of Electronic Publication: 2022 Jun 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mycotoxins*/toxicity
4-Nitroquinoline-1-oxide ; DNA Damage ; Kidney ; Liver ; Mutagenicity Tests/methods ; Mutagens/toxicity ; Sterigmatocystin

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Skocz do pozycji: 5.

Tytuł:: Generation and Application of Inducible Chimeric RNA ASTN2-PAPPA as Knockin Mouse Model.
Autorzy:: Luo Y; Institute of Precision Cancer Medicine and Pathology, School of Medicine and Department of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.
Du L; Department of Biomedical Sciences of Cells & Systems, Section Molecular Cell Biology and Radiation Oncology, University Medical Center Groningen, University of Groningen, 9700 AD Groningen, The Netherlands.; Graduate School, Shantou University Medical College, Shantou 515041, China.
Yao Z; Department of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.; Institute of Precision Cancer Medicine and Pathology, School of Medicine, Jinan University, Guangzhou 510632, China.
Liu F; Institute of Precision Cancer Medicine and Pathology, School of Medicine, Jinan University, Guangzhou 510632, China.
Li K; Institute of Precision Cancer Medicine and Pathology, School of Medicine, Jinan University, Guangzhou 510632, China.
Li F; Department of Oncology, People's Hospital of Leshan, Leshan 614099, China.
Zhu J; Department of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.; Institute of Precision Cancer Medicine and Pathology, School of Medicine, Jinan University, Guangzhou 510632, China.
Coppes RP; Department of Biomedical Sciences of Cells & Systems, Section Molecular Cell Biology and Radiation Oncology, University Medical Center Groningen, University of Groningen, 9700 AD Groningen, The Netherlands.
Zhang D; Department of Bio-Medical Sciences, Philadelphia College of Osteopathic Medicine, 4170 City Avenue, Philadelphia, PA 19131, USA.
Pan Y; Department of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.
Gao S; Henan Key Laboratory of Cancer Epigenetics, College of Clinical Medicine, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, China.
Zhang H; Department of General Surgery, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510632, China.; Institute of Precision Cancer Medicine and Pathology, School of Medicine, Jinan University, Guangzhou 510632, China.; Minister of Education Key Laboratory of Tumor Molecular Biology, Jinan University, Guangzhou 510632, China.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Jan 14; Vol. 11 (2). Date of Electronic Publication: 2022 Jan 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Knock-In Techniques*
RNA, Antisense/*genetics
4-Nitroquinoline-1-oxide ; Animals ; Body Weight/drug effects ; Carcinogens/toxicity ; Disease Models, Animal ; Esophageal Neoplasms/pathology ; Esophageal Squamous Cell Carcinoma/pathology ; Female ; Genotype ; Mice ; Mice, Inbred C57BL ; Mouse Embryonic Stem Cells/drug effects ; Mouse Embryonic Stem Cells/metabolism ; Quinolones ; Tamoxifen/pharmacology

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Skocz do pozycji: 6.

Tytuł:: Investigating the impact of long term exposure to chemical agents on the chromosomal radiosensitivity using human lymphoblastoid GM1899A cells.
Autorzy:: Nuta O; Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, OX11 0RQ, Oxon, UK. .; Department of Biology, School of Sciences and Humanities, Nazarbayev University, Kabanbay Batyr 53, 01000, Nur-Sultan, Kazakhstan. .
Bouffler S; Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, OX11 0RQ, Oxon, UK.
Lloyd D; Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, OX11 0RQ, Oxon, UK.
Ainsbury E; Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, OX11 0RQ, Oxon, UK.
Sepai O; Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, OX11 0RQ, Oxon, UK.
Rothkamm K; Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, OX11 0RQ, Oxon, UK.; Department of Radiotherapy and Radiation Oncology, University Medical Center Hamburg- Eppendorf, 20246, Hamburg, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Jun 16; Vol. 11 (1), pp. 12616. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: 4-Nitroquinoline-1-oxide/*adverse effects
Chromosomes/*genetics
Hydrogen Peroxide/*adverse effects
Lymphocytes/*cytology
Methylnitrosourea/*adverse effects
Cell Line ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Chromosomes/drug effects ; Chromosomes/radiation effects ; Humans ; Lymphocytes/drug effects ; Lymphocytes/radiation effects ; Micronucleus Tests ; Radiation Dosage ; Radiation Tolerance ; Time Factors

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Skocz do pozycji: 7.

Tytuł:: Social isolation stress facilitates chemically induced oral carcinogenesis.
Autorzy:: Verza FA; Laboratory of Psychoneuroimmunology, Psychosomatic Research Center and Oral Oncology Center, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.
Valente VB; Laboratory of Psychoneuroimmunology, Psychosomatic Research Center and Oral Oncology Center, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.
Oliveira LK; Laboratory of Psychoneuroimmunology, Psychosomatic Research Center and Oral Oncology Center, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.
Kayahara GM; Laboratory of Psychoneuroimmunology, Psychosomatic Research Center and Oral Oncology Center, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.; Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
Crivelini MM; Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
Furuse C; Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
Biasoli ÉR; Laboratory of Psychoneuroimmunology, Psychosomatic Research Center and Oral Oncology Center, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.; Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
Miyahara GI; Laboratory of Psychoneuroimmunology, Psychosomatic Research Center and Oral Oncology Center, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.; Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
Oliveira SHP; Department of Basic Sciences, Laboratory of Immunopharmacology, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
Bernabé DG; Laboratory of Psychoneuroimmunology, Psychosomatic Research Center and Oral Oncology Center, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.; Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Jan 07; Vol. 16 (1), pp. e0245190. Date of Electronic Publication: 2021 Jan 07 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Behavior, Animal*
Depression*/metabolism
Depression*/pathology
Depression*/physiopathology
Head and Neck Neoplasms*/chemically induced
Head and Neck Neoplasms*/metabolism
Head and Neck Neoplasms*/pathology
Head and Neck Neoplasms*/physiopathology
Social Isolation*
Squamous Cell Carcinoma of Head and Neck*/chemically induced
Squamous Cell Carcinoma of Head and Neck*/metabolism
Squamous Cell Carcinoma of Head and Neck*/pathology
Squamous Cell Carcinoma of Head and Neck*/physiopathology
Stress, Psychological*/metabolism
Stress, Psychological*/pathology
Stress, Psychological*/physiopathology
4-Nitroquinoline-1-oxide/*toxicity
Animals ; Cytokines/metabolism ; Inflammation Mediators/metabolism ; Male ; Neoplasm Proteins/metabolism ; Rats ; Rats, Wistar

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Skocz do pozycji: 8.

Tytuł:: Single-Cell Analysis of Different Stages of Oral Cancer Carcinogenesis in a Mouse Model.
Autorzy:: Huang LY; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan 701401, Taiwan.
Hsieh YP; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan 701401, Taiwan.
Wang YY; School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Hwang DY; National Institute of Cancer Research, National Health Research Institutes, Tainan 70456, Taiwan.
Jiang SS; National Institute of Cancer Research, National Health Research Institutes, Tainan 70456, Taiwan.
Huang WT; Chi Mei Medical Center, Liouying, Tainan 73659, Taiwan.
Chiang WF; Chi Mei Medical Center, Liouying, Tainan 73659, Taiwan.; School of Dentistry, National Yang Ming University, Taipei 11221, Taiwan.
Liu KJ; National Institute of Cancer Research, National Health Research Institutes, Tainan 70456, Taiwan.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807377, Taiwan.; Institute of Clinical Pharmacy and Pharmaceutical Sciences and Institute of Clinical Medicine, National Cheng Kung University, Tainan 704302, Taiwan.; School of Medical Laboratory Science and Biotechnology, Taipei Medical University, Taipei 110301, Taiwan.
Huang TT; Institute of Oral Medicine, Department of Dentistry, Division of Oral and Maxillofacial Surgery, Department of Stomatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701401, Taiwan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 31; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 31.
Typ publikacji:: Journal Article
MeSH Terms:: Mouth Neoplasms/*genetics
Mouth Neoplasms/*pathology
Precancerous Conditions/*genetics
Precancerous Conditions/*pathology
Tongue Neoplasms/*genetics
Tongue Neoplasms/*pathology
4-Nitroquinoline-1-oxide/toxicity ; Animals ; Arecoline/toxicity ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Carcinogenesis/chemically induced ; Carcinogenesis/pathology ; Carcinogens/toxicity ; Cell Line, Tumor ; Cholinergic Agonists/toxicity ; Disease Models, Animal ; Humans ; Keratinocytes/metabolism ; Keratinocytes/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mouth Neoplasms/chemically induced ; Neoplasm Staging ; Precancerous Conditions/chemically induced ; Proto-Oncogene Proteins c-myc/metabolism ; Sequence Analysis, RNA/methods ; Single-Cell Analysis/methods ; Stem Cells/drug effects ; Stem Cells/metabolism ; Stem Cells/pathology ; Tongue Neoplasms/chemically induced

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Skocz do pozycji: 9.

Tytuł:: Presence of antigenotoxic and anticytotoxic effects of the chalcone 1E,4E-1-(4-chlorophenyl)-5-(2,6,6-trimethylcyclohexen-1-yl)penta-1,4-dien-3-one using in vitro and in vivo assays.
Autorzy:: Lemes SR; Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
eSilva CR; Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Véras JH; Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Chen-Chen L; Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Lima RS; Instituto de Química, Universidade Federal de Goiás, Goiânia, Brazil.
Perez CN; Instituto de Química, Universidade Federal de Goiás, Goiânia, Brazil.
Montes de Sousa MA; Laboratório de Estudos Experimentais e Biotecnológicos, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil.
de Melo Reis PR; Laboratório de Estudos Experimentais e Biotecnológicos, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil.
da Silva Junior NJ; Escola de Medicina, Farmácia e Biomedicina, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil.; Pokaż więcej
Źródło:: Drug and chemical toxicology [Drug Chem Toxicol] 2020 Jul; Vol. 43 (4), pp. 383-390. Date of Electronic Publication: 2018 Sep 11.
Typ publikacji:: Journal Article
MeSH Terms:: Antimutagenic Agents/*pharmacology
Chalcones/*pharmacology
DNA Damage/*drug effects
4-Nitroquinoline-1-oxide/toxicity ; Animals ; Female ; Male ; Mice ; Micronucleus Tests ; Salmonella typhimurium/drug effects ; Sodium Azide/toxicity

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Skocz do pozycji: 10.

Tytuł:: Cytoprotective effects of (E)-N-(2-(3, 5-dimethoxystyryl) phenyl) furan-2-carboxamide (BK3C231) against 4-nitroquinoline 1-oxide-induced damage in CCD-18Co human colon fibroblast cells.
Autorzy:: Tan HH; Center for Toxicology and Health Risk Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Thomas NF; Methodist College Kuala Lumpur, Kuala Lumpur, Malaysia.
Inayat-Hussain SH; Product Stewardship and Toxicology, Group Health, Safety, Security and Environment, Petroliam Nasional Berhad (PETRONAS), Kuala Lumpur, Malaysia.; Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, United States of America.
Chan KM; Center for Toxicology and Health Risk Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 May 04; Vol. 15 (5), pp. e0223344. Date of Electronic Publication: 2020 May 04 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytoprotection*
4-Nitroquinoline-1-oxide/*toxicity
Colon/*drug effects
DNA Damage/*drug effects
Furans/*pharmacology
Mutagens/*toxicity
Stilbenes/*pharmacology
Cell Line ; Colon/cytology ; DNA Repair/drug effects ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Furans/chemistry ; Humans ; Mitochondria/drug effects ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; Stilbenes/chemistry

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Skocz do pozycji: 11.

Tytuł:: A PIK3CA transgenic mouse model with chemical carcinogen exposure mimics human oral tongue tumorigenesis.
Autorzy:: Tan MT; Department of Bioengineering, Rice University, Houston, TX, USA.
Wu JG; Department of Diagnostic and Biomedical Sciences, University of Texas School of Dentistry, Houston, TX, USA.
Callejas-Valera JL; Cancer Biology Research Center, Sanford Research, Sioux Falls, SD, USA.
Schwarz RA; Department of Bioengineering, Rice University, Houston, TX, USA.
Gillenwater AM; Department of Head and Neck Surgery, M.D. Anderson Cancer Center, University of Texas, Houston, TX, USA.
Richards-Kortum RR; Department of Bioengineering, Rice University, Houston, TX, USA.
Vigneswaran N; Department of Diagnostic and Biomedical Sciences, University of Texas School of Dentistry, Houston, TX, USA.; Pokaż więcej
Źródło:: International journal of experimental pathology [Int J Exp Pathol] 2020 Feb; Vol. 101 (1-2), pp. 45-54. Date of Electronic Publication: 2020 May 21.
Typ publikacji:: Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Mutation*
Quinolones*
Cell Transformation, Neoplastic/*chemically induced
Cell Transformation, Neoplastic/*genetics
Class I Phosphatidylinositol 3-Kinases/*genetics
Squamous Cell Carcinoma of Head and Neck/*chemically induced
Squamous Cell Carcinoma of Head and Neck/*genetics
Tongue Neoplasms/*chemically induced
Tongue Neoplasms/*genetics
4-Nitroquinoline-1-oxide ; Animals ; Cell Proliferation ; Cell Transformation, Neoplastic/pathology ; Disease Models, Animal ; Disease Progression ; Lymphocytes/pathology ; Mice, Inbred CBA ; Mice, Transgenic ; Oncogene Proteins, Viral/genetics ; Squamous Cell Carcinoma of Head and Neck/pathology ; Time Factors ; Tongue Neoplasms/pathology

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Skocz do pozycji: 12.

Tytuł:: Establishing of mouse oral carcinoma cell lines derived from transgenic mice and their use as syngeneic tumorigenesis models.
Autorzy:: Chen YF; Institute of Oral Biology, School of Dentistry, National Yang-Ming University, No. 155, Li-Nong St., Section 2, Beitou District, Taipei, 112, Taiwan.
Liu CJ; Institute of Oral Biology, School of Dentistry, National Yang-Ming University, No. 155, Li-Nong St., Section 2, Beitou District, Taipei, 112, Taiwan.; Department of Dentistry, MacKay Memorial Hospital, No. 45, Minsheng Rd., Tamsui District, New Taipei City, 251, Taiwan.
Lin LH; Department of Dentistry, MacKay Memorial Hospital, No. 45, Minsheng Rd., Tamsui District, New Taipei City, 251, Taiwan.
Chou CH; Institute of Oral Biology, School of Dentistry, National Yang-Ming University, No. 155, Li-Nong St., Section 2, Beitou District, Taipei, 112, Taiwan.
Yeh LY; Institute of Oral Biology, School of Dentistry, National Yang-Ming University, No. 155, Li-Nong St., Section 2, Beitou District, Taipei, 112, Taiwan.
Lin SC; Institute of Oral Biology, School of Dentistry, National Yang-Ming University, No. 155, Li-Nong St., Section 2, Beitou District, Taipei, 112, Taiwan. .; Department of Dentistry, School of Dentistry, National Yang-Ming University, No. 155, Li-Nong St., Section 2, Beitou District, Taipei, 112, Taiwan. .; Department of Stomatology, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou District, Taipei, 112, Taiwan. .
Chang KW; Institute of Oral Biology, School of Dentistry, National Yang-Ming University, No. 155, Li-Nong St., Section 2, Beitou District, Taipei, 112, Taiwan. .; Department of Dentistry, School of Dentistry, National Yang-Ming University, No. 155, Li-Nong St., Section 2, Beitou District, Taipei, 112, Taiwan. .; Department of Stomatology, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou District, Taipei, 112, Taiwan. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2019 Mar 29; Vol. 19 (1), pp. 281. Date of Electronic Publication: 2019 Mar 29.
Typ publikacji:: Journal Article
MeSH Terms:: 4-Nitroquinoline-1-oxide/*toxicity
Carcinoma, Squamous Cell/*pathology
Cell Culture Techniques/*methods
ErbB Receptors/*genetics
MicroRNAs/*genetics
Tongue Neoplasms/*pathology
Animals ; Carcinoma, Squamous Cell/chemically induced ; Carcinoma, Squamous Cell/genetics ; Cell Line, Tumor ; Epithelial-Mesenchymal Transition ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Mutation, Missense ; Tongue Neoplasms/chemically induced ; Tongue Neoplasms/genetics ; Tumor Microenvironment ; Tumor Suppressor Protein p53/genetics

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Skocz do pozycji: 13.

Tytuł:: Alterations of 63 hub genes during lingual carcinogenesis in C57BL/6J mice.
Autorzy:: Liu H; Department of Oral and Maxillofacial surgery, the Fourth Affiliated Hospital of Kunming Medical University, No. 176, Qinnian Road, Kunming city, Yunnan Province, China.
Li J; Maxillofacial Service of the Department of Plastic Surgery, the First Affiliated Hospital of Kunming Medical University, No. 295, Xichang Road, Kunming city, Yunnan Province, China.
Yang Y; Department of Pathology, the First Affiliated Hospital of Kunming Medical University, No. 295, Xichang Road, Kunming city, Yunnan Province, China.
Liu L; Maxillofacial Service of the Department of Plastic Surgery, the First Affiliated Hospital of Kunming Medical University, No. 295, Xichang Road, Kunming city, Yunnan Province, China.
Yu L; Maxillofacial Service of the Department of Plastic Surgery, the First Affiliated Hospital of Kunming Medical University, No. 295, Xichang Road, Kunming city, Yunnan Province, China.
Tu M; Maxillofacial Service of the Department of Plastic Surgery, the First Affiliated Hospital of Kunming Medical University, No. 295, Xichang Road, Kunming city, Yunnan Province, China.
Yuan R; Maxillofacial Service of the Department of Plastic Surgery, the First Affiliated Hospital of Kunming Medical University, No. 295, Xichang Road, Kunming city, Yunnan Province, China.
Yue W; Department of Oral and Maxillofacial surgery, the Fourth Affiliated Hospital of Kunming Medical University, No. 176, Qinnian Road, Kunming city, Yunnan Province, China.
Luo Q; Department of Oral and Maxillofacial surgery, the Fourth Affiliated Hospital of Kunming Medical University, No. 176, Qinnian Road, Kunming city, Yunnan Province, China.
Ruan Y; Department of Pathology, Kunming Medical University, No. 1168, Chunrongxi Road, Chenggong District, Kunming city, Yunnan Province, China.
Dai X; Maxillofacial Service of the Department of Plastic Surgery, the First Affiliated Hospital of Kunming Medical University, No. 295, Xichang Road, Kunming city, Yunnan Province, China. multon_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2018 Aug 22; Vol. 8 (1), pp. 12626. Date of Electronic Publication: 2018 Aug 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Tongue Neoplasms/*genetics
Tongue Neoplasms/*pathology
4-Nitroquinoline-1-oxide/pharmacology ; Animals ; Biomarkers, Tumor/metabolism ; Carcinogenesis/genetics ; Carcinogens/metabolism ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/pathology ; Cell Transformation, Neoplastic/genetics ; DNA Methylation ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Mice ; Mice, Inbred C57BL/genetics ; Mouth Mucosa/metabolism ; Mouth Neoplasms/genetics ; Mouth Neoplasms/pathology ; Promoter Regions, Genetic/genetics ; Tongue/metabolism

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Skocz do pozycji: 14.

Tytuł:: Negative terpinen-4-ol modulate potentially malignant and malignant lingual lesions induced by 4-nitroquinoline-1-oxide in rat model
Autorzy:: Neto, José Nunes Carneiro
Sorbo, Juliana Maria
Filho, Carlos Alberto Arcaro
Sabino, Thaís Fernanda Moreira
Ribeiro, Daniel Araki
Brunetti, Iguatemy Lourenço
de Andrade, Cleverton RobertoAff4, IDs00210022022757_cor7; Pokaż więcej
Źródło:: Naunyn-Schmiedeberg's Archives of Pharmacology. 395(11):1387-1403

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Szczegóły

Skocz do pozycji: 15.

Tytuł:: Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence.
Autorzy:: Matrka MC; Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America.
Cimperman KA; Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America.
Haas SR; Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America.
Guasch G; Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS, UMR7258, Institute Paoli-Calmettes, Aix-Marseille University, Marseille, France.
Ehrman LA; Division of Experimental Hematology & Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America.
Waclaw RR; Division of Experimental Hematology & Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America.
Komurov K; Division of Experimental Hematology & Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America.
Lane A; Division of Bone Marrow Transplant and Immune Deficiency, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America.
Wikenheiser-Brokamp KA; Division of Pathology & Laboratory Medicine and Perinatal Institute Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center and Department of Pathology & Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.
Wells SI; Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America.; Division of Experimental Hematology & Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2018 Mar 14; Vol. 14 (3), pp. e1007227. Date of Electronic Publication: 2018 Mar 14 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Carcinoma, Squamous Cell/*genetics
Carcinoma, Squamous Cell/*pathology
DNA-Binding Proteins/*genetics
Esophageal Neoplasms/*genetics
Esophageal Neoplasms/*pathology
Oncogene Proteins/*genetics
Poly-ADP-Ribose Binding Proteins/*genetics
4-Nitroquinoline-1-oxide/toxicity ; Animals ; Carcinoma, Squamous Cell/chemically induced ; DNA-Binding Proteins/metabolism ; Epithelium/pathology ; Esophageal Neoplasms/chemically induced ; Esophageal Squamous Cell Carcinoma ; Gene Expression Regulation, Neoplastic ; Keratinocytes/pathology ; Mice, Transgenic ; Oncogene Proteins/metabolism ; Poly-ADP-Ribose Binding Proteins/metabolism ; Response Elements/drug effects ; Response Elements/genetics ; Tetracycline/pharmacology ; Tongue/drug effects ; Tongue/pathology ; Transgenes

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Skocz do pozycji: 16.

Tytuł:: Transcriptional Profiling of Saccharomyces cerevisiae Reveals the Impact of Variation of a Single Transcription Factor on Differential Gene Expression in 4NQO, Fermentable, and Nonfermentable Carbon Sources.
Autorzy:: Rong-Mullins X; Department of Biology, West Virginia University, Morgantown, West Virginia 26506.
Ayers MC; Department of Biology, West Virginia University, Morgantown, West Virginia 26506.
Summers M; Department of Biology, West Virginia University, Morgantown, West Virginia 26506.
Gallagher JEG; Department of Biology, West Virginia University, Morgantown, West Virginia 26506 .; Pokaż więcej
Źródło:: G3 (Bethesda, Md.) [G3 (Bethesda)] 2018 Feb 02; Vol. 8 (2), pp. 607-619. Date of Electronic Publication: 2018 Feb 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Gene Expression Profiling*
4-Nitroquinoline-1-oxide/*pharmacology
Carbon/*metabolism
Gene Expression Regulation, Fungal/*drug effects
Saccharomyces cerevisiae/*genetics
Transcription Factors/*genetics
ATP-Binding Cassette Transporters/genetics ; ATP-Binding Cassette Transporters/metabolism ; Alleles ; Fermentation ; Mutagens/pharmacology ; Mutation ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Transcription Factors/metabolism

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Skocz do pozycji: 17.

Tytuł:: Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA.
Autorzy:: Iyer DR; Department of Biochemistry & Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
Rhind N; Department of Biochemistry & Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2017 Aug 14; Vol. 13 (8), pp. e1006958. Date of Electronic Publication: 2017 Aug 14 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: DNA Damage*
DNA Replication*
Gene Expression Regulation, Fungal*
S Phase Cell Cycle Checkpoints*
Schizosaccharomyces/*genetics
4-Nitroquinoline-1-oxide ; Bleomycin ; DNA, Fungal/genetics ; Methyl Methanesulfonate ; Replication Protein A/genetics ; Replication Protein A/metabolism ; Schizosaccharomyces pombe Proteins/genetics ; Schizosaccharomyces pombe Proteins/metabolism

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Skocz do pozycji: 18.

Tytuł:: Areca nut is associated with younger age of diagnosis, poor chemoradiotherapy response, and shorter overall survival in esophageal squamous cell carcinoma.
Autorzy:: Chen CH; Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Department of Applied Chemistry, and Graduate Institute of Biomedicine and Biomedical Technology, National Chi-Nan University, Taiwan.
Lu HI; Department of Thoracic & Cardiovascular Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Wang YM; Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Chen YH; Department of Hematology-Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Lo CM; Department of Thoracic & Cardiovascular Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Huang WT; Department of Pathology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Li SH; Department of Hematology-Oncology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Feb 28; Vol. 12 (2), pp. e0172752. Date of Electronic Publication: 2017 Feb 28 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Areca/*adverse effects
Carcinoma, Squamous Cell/*etiology
Esophageal Neoplasms/*etiology
Nuts/*adverse effects
4-Nitroquinoline-1-oxide/toxicity ; Adult ; Aged ; Aged, 80 and over ; Animals ; Antineoplastic Agents/therapeutic use ; Arecoline/adverse effects ; Carcinoma, Squamous Cell/chemically induced ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/pathology ; Esophageal Neoplasms/chemically induced ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Esophageal Squamous Cell Carcinoma ; Female ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Retrospective Studies

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Skocz do pozycji: 19.

Tytuł:: Comparison of injectable doxorubicin & its nanodrug complex chemotherapy for the treatment of 4-nitroquinoline-1-oxide induced oral squamous cell carcinoma in rats.
Autorzy:: Khiavi MM; Department of Oral & Maxillofacial Pathology, Faculty of Dentistry, Tehran University of Medical Sciences, International Campus, Tehran, Iran.
Abdal K; Department of Oral & Maxillofacial Pathology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Abbasi MM; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hamishehkar H; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Aghbali AA; Department of Oral & Maxillofacial Pathology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Salehi R; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Sina M; Department of Oral & Maxillofacial Pathology, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Abdollahi B; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Fotohi S; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Pokaż więcej
Źródło:: The Indian journal of medical research [Indian J Med Res] 2017 Jan; Vol. 145 (1), pp. 112-117.
Typ publikacji:: Journal Article
MeSH Terms:: Drug Delivery Systems*
Carcinoma, Squamous Cell/*drug therapy
Doxorubicin/*administration & dosage
Head and Neck Neoplasms/*drug therapy
Nanoparticles/*administration & dosage
4-Nitroquinoline-1-oxide/toxicity ; Animals ; Carcinoma, Squamous Cell/chemically induced ; Carcinoma, Squamous Cell/pathology ; Disease Models, Animal ; Doxorubicin/chemistry ; Head and Neck Neoplasms/chemically induced ; Head and Neck Neoplasms/pathology ; Humans ; Methotrexate/administration & dosage ; Methotrexate/chemistry ; Nanoparticles/chemistry ; Rats ; Squamous Cell Carcinoma of Head and Neck

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Skocz do pozycji: 20.

Tytuł:: Bmi1-positive cells in the lingual epithelium could serve as cancer stem cells in tongue cancer.
Autorzy:: Tanaka T; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.; Third Department of Internal Medicine, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.; Department of Surgery, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Atsumi N; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Nakamura N; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.; Department of Surgery, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Yanai H; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.; Department of Urology and Andrology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Komai Y; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.; Department of Pediatrics, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Omachi T; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Tanaka K; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Ishigaki K; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Saiga K; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Ohsugi H; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.; Department of Pediatrics, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Tokuyama Y; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Imahashi Y; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Hisha H; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Yoshida N; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Kumano K; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Okazaki K; Third Department of Internal Medicine, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.
Ueno H; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka 573-1010, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Dec 22; Vol. 6, pp. 39386. Date of Electronic Publication: 2016 Dec 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Lineage/*physiology
Epithelium/*metabolism
Neoplastic Stem Cells/*metabolism
Polycomb Repressive Complex 1/*metabolism
Proto-Oncogene Proteins/*metabolism
Tongue Neoplasms/*metabolism
4-Nitroquinoline-1-oxide/pharmacology ; Animals ; Cell Proliferation/drug effects ; Mice ; Mice, Inbred C57BL ; Tongue/metabolism ; Tongue Neoplasms/chemically induced

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