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Wyświetlanie 1-20 z 6536
Tytuł:
Promising anticonvulsant and/or analgesic compounds among 5-chloro-2- or 5-chloro-4-methyl derivatives of xanthone coupled to aminoalkanol moieties-Design, synthesis and pharmacological evaluation.
Autorzy:
Mazur G; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Pańczyk-Straszak K; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Rapacz A; Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Kiszela J; Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Smolik M; Chair and Department of Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Gawlik M; Chair and Department of Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Walczak M; Chair and Department of Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Czekajewska J; Department of Microbiology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Poloczek C; Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Karczewska E; Department of Microbiology, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Żesławska E; Institute of Biology, Pedagogical University of Krakow, Kraków, Poland.
Nitek W; Department of Crystallochemistry and Crystallophysics, Faculty of Chemistry, Jagiellonian University, Kraków, Poland.
Niedbał A; Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Leśniak J; Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Ciapala K; Department of Pain Pharmacology, Maj Institute of Pharmacology, Kraków, Poland.
Pawlik K; Department of Pain Pharmacology, Maj Institute of Pharmacology, Kraków, Poland.
Mika J; Department of Pain Pharmacology, Maj Institute of Pharmacology, Kraków, Poland.
Waszkielewicz AM; Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Pokaż więcej
Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2023 Feb; Vol. 101 (2), pp. 278-325. Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anticonvulsants*/pharmacology
Anticonvulsants*/therapeutic use
Xanthones*/pharmacology
Xanthones*/therapeutic use
Xanthones*/chemistry
Mice ; Animals ; Seizures/drug therapy ; Electroshock ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of the closed-loop hippocampal low-frequency stimulation on seizure severity, learning, and memory in pilocarpine epilepsy rat model.
Autorzy:
Zare M; Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Rezaei M; Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Nazari M; Department of Technology, Electrical Engineering, Sharif University, Tehran, Iran.
Kosarmadar N; Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Faraz M; Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Barkley V; Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Shojaei A; Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Raoufy MR; Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Mirnajafi-Zadeh J; Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.; Institute for Brain Sciences and Cognition, Tarbiat Modares University, Tehran, Iran.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14656.
Typ publikacji:
Journal Article
MeSH Terms:
Pilocarpine*/toxicity
Epilepsy*
Humans ; Male ; Rats ; Animals ; Rats, Wistar ; Seizures/chemically induced ; Seizures/therapy ; Anticonvulsants ; Hippocampus ; Maze Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of ANXA2 activity attenuates epileptic susceptibility and GluA1 phosphorylation.
Autorzy:
Ma, Limin (AUTHOR)
Wu, Qingyuan (AUTHOR)
Yuan, Jinxian (AUTHOR)
Wang, You (AUTHOR)
Zhang, Peng (AUTHOR)
Liu, Qiankun (AUTHOR)
Tan, Dandan (AUTHOR)
Liang, Minxue (AUTHOR)
Chen, Yangmei (AUTHOR)
Pokaż więcej
Źródło:
CNS Neuroscience & Therapeutics. Nov2023, Vol. 29 Issue 11, p3644-3656. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nano-delivery systems as a promising therapeutic potential for epilepsy: Current status and future perspectives.
Autorzy:
Movahedpour A; Behbahan Faculty of Medical Sciences, Behbahan, Iran.
Taghvaeefar R; Behbahan Faculty of Medical Sciences, Behbahan, Iran.
Asadi-Pooya AA; Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Neurology, Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Karami Y; Department of Clinical Science, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.
Tavasolian R; Department of Clinical Science and Nutrition, University of Chester, Chester, UK.
Khatami SH; Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Soltani Fard E; Department of Molecular Medicine, School of Advanced Technologies, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Taghvimi S; Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Karami N; TU Wien, Institute of Solid State Electronics, Vienna, Austria.
Rahimi Jaberi K; Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.
Taheri-Anganeh M; Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
Ghasemi H; Abadan University of Medical Sciences, Abadan, Iran.
Pokaż więcej
Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 Nov; Vol. 29 (11), pp. 3150-3159. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Epilepsy*/drug therapy
Exosomes*
Humans ; Blood-Brain Barrier ; Drug Delivery Systems ; Anticonvulsants/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
AMPAR receptor inhibitors suppress proliferation of human small cell lung cancer cell lines.
Autorzy:
Masumoto, Nami (AUTHOR)
Kato, Shingo (AUTHOR)
Aichi, Masahiro (AUTHOR)
Hasegawa, Sho (AUTHOR)
Sahara, Kota (AUTHOR)
Suyama, Kumiko (AUTHOR)
Sano, Akane (AUTHOR)
Miyazaki, Tomoyuki (AUTHOR)
Okudela, Koji (AUTHOR)
Kaneko, Takeshi (AUTHOR)
Takahashi, Takuya (AUTHOR)
Pokaż więcej
Źródło:
Thoracic Cancer. Oct2023, Vol. 14 Issue 29, p2897-2908. 12p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association between human leukocyte antigens and cutaneous adverse drug reactions to antiepileptics and antibiotics in the Iranian population.
Autorzy:
Mortazavi H; Department of Dermatology Tehran University of Medical Sciences, Razi Hospital, Tehran, Iran.
Rostami A; Department of Dermatology Tehran University of Medical Sciences, Razi Hospital, Tehran, Iran.
Firooz A; Center for Research & Training in Skin Diseases & Leprosy, Tehran University of Medical Sciences, Tehran, Iran.
Esmaili N; Department of Dermatology Tehran University of Medical Sciences, Razi Hospital, Tehran, Iran.; Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Razi Hospital, Tehran, Iran.
Ghiasi M; Department of Dermatology Tehran University of Medical Sciences, Razi Hospital, Tehran, Iran.
Lajevardi V; Department of Dermatology Tehran University of Medical Sciences, Razi Hospital, Tehran, Iran.
Amirzargar AA; Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran.; Immunogenetic Laboratory, Department of Immunology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Sheykhi I; Industrial Engineering Department, Sharif University of Technology, Tehran, Iran.
Khamesipour A; Center for Research & Training in Skin Diseases & Leprosy, Tehran University of Medical Sciences, Tehran, Iran.
Akhdar M; Department of Dermatology Tehran University of Medical Sciences, Razi Hospital, Tehran, Iran.
Pokaż więcej
Źródło:
Dermatologic therapy [Dermatol Ther] 2022 May; Vol. 35 (5), pp. e15393. Date of Electronic Publication: 2022 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
Anticonvulsants*/adverse effects
Stevens-Johnson Syndrome*/etiology
Adult ; Anti-Bacterial Agents/adverse effects ; Carbamazepine/adverse effects ; Case-Control Studies ; Ciprofloxacin/adverse effects ; Female ; Genotype ; HLA Antigens/genetics ; HLA-A Antigens/genetics ; HLA-B Antigens/genetics ; HLA-DRB1 Chains/genetics ; Humans ; Iran ; Lamotrigine ; Male ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Long-term music adjuvant therapy enhances the efficacy of sub-dose antiepileptic drugs in temporal lobe epilepsy.
Autorzy:
Xu CL; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, Zhejiang Chinese Medical University, Hangzhou, China.
Nao JZ; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Shen YJ; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Gong YW; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Tan B; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, Zhejiang Chinese Medical University, Hangzhou, China.
Zhang S; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Shen KX; Institute of Drug Metabolism and Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Sun CR; Institute of Drug Metabolism and Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
Wang Y; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, Zhejiang Chinese Medical University, Hangzhou, China.
Chen Z; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, Zhejiang Chinese Medical University, Hangzhou, China.
Pokaż więcej
Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2022 Feb; Vol. 28 (2), pp. 206-217. Date of Electronic Publication: 2021 Feb 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Music Therapy*
Anticonvulsants/*pharmacology
Epilepsy, Temporal Lobe/*therapy
Animals ; Anticonvulsants/administration & dosage ; Combined Modality Therapy ; Disease Models, Animal ; Electroencephalography ; Epilepsy, Temporal Lobe/drug therapy ; Male ; Mice ; Mice, Inbred C57BL ; Time Factors ; Valproic Acid/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Management of status epilepticus: a narrative review.
Autorzy:
Migdady I; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Rosenthal ES; Department of Neurology, Divisions of Clinical Neurophysiology and Neurocritical Care Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Cock HR; Clinical Neurosciences Academic Group, Institute of Molecular and Clinical Sciences, St. George's University of London, London, UK.
Pokaż więcej
Źródło:
Anaesthesia [Anaesthesia] 2022 Jan; Vol. 77 Suppl 1, pp. 78-91.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Disease Management*
Anesthetics/*therapeutic use
Anticonvulsants/*therapeutic use
Evidence-Based Medicine/*methods
Status Epilepticus/*drug therapy
Status Epilepticus/*surgery
Anesthetics/pharmacology ; Anticonvulsants/pharmacology ; Electroencephalography/drug effects ; Electroencephalography/methods ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Seizure freedom and plasma levels of newer generation antiseizure medications.
Autorzy:
Aícua-Rapún I; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.
André P; Clinical Pharmacology Service, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.
Rossetti AO; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.
Décosterd LA; Laboratory of Clinical Pharmacology, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.
Buclin T; Clinical Pharmacology Service, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.
Novy J; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.
Pokaż więcej
Źródło:
Acta neurologica Scandinavica [Acta Neurol Scand] 2021 Aug; Vol. 144 (2), pp. 202-208. Date of Electronic Publication: 2021 May 05.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Anticonvulsants/*blood
Anticonvulsants/*pharmacokinetics
Epilepsy/*drug therapy
Adolescent ; Adult ; Aged ; Anticonvulsants/therapeutic use ; Cohort Studies ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Seizures/drug therapy ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Editorial: topiramate for cyclic vomiting syndrome-for refractory patients only?
Autorzy:
Rangan V; Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Lembo AJ; Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Pokaż więcej
Źródło:
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2021 Aug; Vol. 54 (4), pp. 500-501.
Typ publikacji:
Editorial; Comment
MeSH Terms:
Anticonvulsants*/therapeutic use
Vomiting*/chemically induced
Vomiting*/drug therapy
Humans ; Topiramate/therapeutic use
SCR Disease Name:
Familial cyclic vomiting syndrome
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Polycystic ovarian syndrome in Nigerian women with epilepsy on carbamazepine/levetiracetam monotherapy.
Autorzy:
Ogunjimi L; Department of Pharmacology and Therapeutics, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu, Nigeria.
Yaria J; Department of Medicine, University College Hospital, Ibadan, Nigeria.
Makanjuola A; Department of Medicine, University College Hospital, Ibadan, Nigeria.
Alabi A; Department of Pharmacology and Therapeutics, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu, Nigeria.
Osalusi B; Department of Medicine, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu, Nigeria.
Oboh D; Department of Radiology, University College Hospital, Ibadan, Nigeria.
Olusola-Bello M; Radiology Unit, Department of Surgery, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu, Nigeria.
Olawale O; Department of Chemical Pathology and Immunology, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu, Nigeria.
Ogunniyi A; Department of Medicine, University College Hospital, Ibadan, Nigeria.
Pokaż więcej
Źródło:
Acta neurologica Scandinavica [Acta Neurol Scand] 2021 Feb; Vol. 143 (2), pp. 146-153. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Anticonvulsants/*adverse effects
Carbamazepine/*adverse effects
Epilepsy/*drug therapy
Levetiracetam/*adverse effects
Polycystic Ovary Syndrome/*epidemiology
Adult ; Anticonvulsants/administration & dosage ; Anticonvulsants/therapeutic use ; Carbamazepine/administration & dosage ; Carbamazepine/therapeutic use ; Female ; Humans ; Levetiracetam/administration & dosage ; Levetiracetam/therapeutic use ; Nigeria ; Polycystic Ovary Syndrome/etiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cannabidiol in conjunction with clobazam: analysis of four randomized controlled trials.
Autorzy:
Gunning B; Stichting Epilepsie Instellingen Nederland, Zwolle, The Netherlands.
Mazurkiewicz-Bełdzińska M; Medical University of Gdańsk, Gdańsk, Poland.
Chin RFM; Royal Hospital for Sick Children, Edinburgh, UK.
Bhathal H; Centro Médico Teknon, Neurocenter Barcelona, Barcelona, Spain.
Nortvedt C; GW Research Ltd, Cambridge, UK.
Dunayevich E; Greenwich Biosciences, Inc, Carlsbad, CA, USA.
Checketts D; GW Research Ltd, Cambridge, UK.
Pokaż więcej
Źródło:
Acta neurologica Scandinavica [Acta Neurol Scand] 2021 Feb; Vol. 143 (2), pp. 154-163. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji:
Journal Article; Meta-Analysis
MeSH Terms:
Anticonvulsants/*therapeutic use
Cannabidiol/*therapeutic use
Clobazam/*therapeutic use
Epilepsies, Myoclonic/*drug therapy
Lennox Gastaut Syndrome/*drug therapy
Adult ; Anticonvulsants/administration & dosage ; Anticonvulsants/adverse effects ; Cannabidiol/administration & dosage ; Cannabidiol/adverse effects ; Clobazam/administration & dosage ; Clobazam/adverse effects ; Female ; Humans ; Male ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy and safety of cenobamate in patients with uncontrolled focal seizures: A meta-analysis.
Autorzy:
Zhang L; Department of Pediatrics, Yancheng Maternal and Children's Health Hospital, Yancheng, China.
Wang J; Department of Pediatrics, Yancheng Maternal and Children's Health Hospital, Yancheng, China.
Wang C; Department of Pediatrics, Yancheng Maternal and Children's Health Hospital, Yancheng, China.
Pokaż więcej
Źródło:
Acta neurologica Scandinavica [Acta Neurol Scand] 2021 Jul; Vol. 144 (1), pp. 58-66. Date of Electronic Publication: 2021 Mar 31.
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:
Anticonvulsants/*administration & dosage
Carbamates/*administration & dosage
Chlorophenols/*administration & dosage
Drug Resistant Epilepsy/*drug therapy
Seizures/*drug therapy
Tetrazoles/*administration & dosage
Anticonvulsants/adverse effects ; Carbamates/adverse effects ; Chlorophenols/adverse effects ; Dizziness/chemically induced ; Dose-Response Relationship, Drug ; Drug Resistant Epilepsy/diagnosis ; Fatigue/chemically induced ; Humans ; Nausea/chemically induced ; Randomized Controlled Trials as Topic/methods ; Seizures/diagnosis ; Tetrazoles/adverse effects ; Treatment Outcome ; Vertigo/chemically induced
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Off‐label pharmacological treatment for neuropathic pain: A Delphi study by the Spanish Pain Society Neuropathic Pain Task Force.
Autorzy:
Serrano, Ancor
Gálvez, Rafael
Paremés, Elena
Navarro, Ana
Ochoa, Dolores
Pérez, Concepción
Pokaż więcej
Źródło:
Pain Practice. Feb2023, Vol. 23 Issue 2, p167-179. 13p. 1 Black and White Photograph, 1 Diagram, 2 Charts, 1 Graph.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy and safety of fenfluramine in patients with Dravet syndrome: A meta-analysis.
Autorzy:
Zhang L; Department of Pediatrics, Yancheng Maternal and Children's Health Hospital, Yancheng, China.
Li W; Department of Medical Imaging, Jiangsu Vocational College of Medicine, Yancheng, China.
Wang C; Department of Pediatrics, Yancheng Maternal and Children's Health Hospital, Yancheng, China.
Pokaż więcej
Źródło:
Acta neurologica Scandinavica [Acta Neurol Scand] 2021 Apr; Vol. 143 (4), pp. 339-348. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:
Anticonvulsants/*therapeutic use
Epilepsies, Myoclonic/*diagnosis
Epilepsies, Myoclonic/*drug therapy
Fenfluramine/*therapeutic use
Anticonvulsants/adverse effects ; Child ; Child, Preschool ; Fatigue/chemically induced ; Fenfluramine/adverse effects ; Fever/chemically induced ; Humans ; Multicenter Studies as Topic/methods ; Randomized Controlled Trials as Topic/methods ; Seizures/drug therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy, safety, and tolerability of adjunctive perampanel in patients from China with focal seizures or generalized tonic-clonic seizures: Post hoc analysis of phase III double-blind and open-label extension studies.
Autorzy:
Weiping L; Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, Guangdong, China.
Dong Z; West China Hospital, Sichuan, China.
Zhen H; Shanghai Huashan Hospital (affiliated to Fudan University), Shanghai, China.
Patten A; Eisai Ltd., Hatfield, UK.
Dash A; Eisai Singapore Pte. Ltd., Singapore.
Malhotra M; Eisai Inc., Woodcliff Lake, NJ, USA.
Pokaż więcej
Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2021 Mar; Vol. 27 (3), pp. 330-340.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Anticonvulsants/*administration & dosage
Nitriles/*administration & dosage
Pyridones/*administration & dosage
Seizures/*diagnosis
Seizures/*drug therapy
Adolescent ; Adult ; Anticonvulsants/adverse effects ; China/epidemiology ; Double-Blind Method ; Drug Therapy, Combination ; Female ; Gastrointestinal Diseases/chemically induced ; Humans ; Male ; Nitriles/adverse effects ; Pyridones/adverse effects ; Seizures/epidemiology ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis, in silico screening, and biological evaluation of novel pyridine congeners as anti‐epileptic agents targeting AMPA (α‐amino‐3‐hydroxy‐5‐methylisoxazole) receptors.
Autorzy:
Tyagi, Shivani (AUTHOR)
Mishra, Rakhi (AUTHOR)
Mazumder, Avijit (AUTHOR)
Mazumder, Rupa (AUTHOR)
Singh, Gurvinder (AUTHOR)
Pandey, Pratibha (AUTHOR)
Pokaż więcej
Źródło:
Chemical Biology & Drug Design. Mar2024, Vol. 103 Issue 3, p1-20. 20p.
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 6536

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