Synthesis of a dual carbon-14-labeled calcitonin gene-related peptide receptor antagonist for use in a human absorption-distribution-metabolism-elimination study.
Autorzy:
Turley WA; Research and Early Development, Discovery Chemistry Platforms, Radiochemistry, Bristol Myers Squibb, Princeton, New Jersey, USA. Easter JA; Research and Early Development, Discovery Chemistry Platforms, Radiochemistry, Bristol Myers Squibb, Princeton, New Jersey, USA. BurrellRC; Research and Early Development, Discovery Chemistry Platforms, Radiochemistry, Bristol Myers Squibb, Princeton, New Jersey, USA. Bonacorsi SJ Jr; Research and Early Development, Discovery Chemistry Platforms, Radiochemistry, Bristol Myers Squibb, Princeton, New Jersey, USA.
Synthesis of carbon-14 and stable isotope labeled Censavudine.
Autorzy:
BurrellRC; Research and Early Development, Discovery Chemistry Platforms, Radiochemistry, Bristol Myers Squibb, Princeton, New Jersey, USA. Bonacorsi SJ Jr; Research and Early Development, Discovery Chemistry Platforms, Radiochemistry, Bristol Myers Squibb, Princeton, New Jersey, USA. Ortiz A; Global Product Development & Supply, Chemical and Synthetic Development, Bristol Myers Squibb, New Brunswick, New Jersey, USA. Benkovics T; Global Product Development & Supply, Chemical and Synthetic Development, Bristol Myers Squibb, New Brunswick, New Jersey, USA. Shi Z; Global Product Development & Supply, Chemical and Synthetic Development, Bristol Myers Squibb, New Brunswick, New Jersey, USA.
Synthesis of isotopically labeled daclatasvir for use in human clinical studies.
Autorzy:
Easter JA; Bristol-Myers Squibb Research and Development, Discovery Chemistry Platforms-Radiochemistry, 5 Research Parkway, Wallingford, CT, 06424, USA. BurrellRC; Bristol-Myers Squibb Research and Development, Discovery Chemistry Platforms-Radiochemistry, 5 Research Parkway, Wallingford, CT, 06424, USA. Bonacorsi SJ Jr; Discovery Chemistry Platforms-Radiochemistry, Route 206 and Province Line Road, Princeton, NJ, 08540, USA.
Synthesis of stable isotope-labeled epothilone D using a degradation-reconstruction approach.
Autorzy:
BurrellRC; Bristol-Myers Squibb Research and Development, Discovery Chemistry Platforms, 5 Research Parkway, Wallingford, CT, 06492, USA. Turley WA; Bristol-Myers Squibb Research and Development, Discovery Chemistry Platforms, 5 Research Parkway, Wallingford, CT, 06492, USA. Bonacorsi SJ Jr; Bristol-Myers Squibb Research and Development, Discovery Chemistry Platforms, Route 206 and Province Line Road, Princeton, NJ, 08540, USA.
An alternative and robust synthesis of [(13) C4 ]Baraclude® (entecavir).
Autorzy:
Easter JA; Radiochemical Synthesis Group, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT, 06492, USA. BurrellRC Bonacorsi SJ Jr
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