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Tytuł:
A macrophage-cell model of HIV latency reveals the unusual importance of the bromodomain axis.
Autorzy:
Kisaka JK; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, 63110, USA.
Rauch D; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, 63110, USA.
Griffith M; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, 63110, USA.; McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, MO, 63108, USA.
Kyei GB; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, 63110, USA. .; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, 63110, USA. .; Department of Virology, College of Health Sciences, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana. .; Medical and Scientific Research Center, University of Ghana Medical Center, Accra, Ghana. .
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Źródło:
Virology journal [Virol J] 2024 Apr 05; Vol. 21 (1), pp. 80. Date of Electronic Publication: 2024 Apr 05.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*
HIV-1*/genetics
Humans ; Virus Latency/genetics ; Virus Activation ; Transcription Factors ; Nuclear Proteins ; Macrophages ; CD4-Positive T-Lymphocytes ; Bromodomain Containing Proteins ; Cell Cycle Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The cell biology of HIV-1 latency and rebound.
Autorzy:
Mbonye U; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA. .
Karn J; Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA. .
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Źródło:
Retrovirology [Retrovirology] 2024 Apr 05; Vol. 21 (1), pp. 6. Date of Electronic Publication: 2024 Apr 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV-1*/physiology
HIV Infections*
Humans ; Virus Latency ; Positive Transcriptional Elongation Factor B/genetics ; Positive Transcriptional Elongation Factor B/metabolism ; CD4-Positive T-Lymphocytes ; Proviruses/metabolism ; Virus Activation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV-1 Vpr Functions in Primary CD4 T Cells.
Autorzy:
Vanegas-Torres CA; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, 72076 Tuebingen, Germany.
Schindler M; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tuebingen, 72076 Tuebingen, Germany.
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Źródło:
Viruses [Viruses] 2024 Mar 09; Vol. 16 (3). Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV-1*/genetics
HIV Seropositivity*
HIV Infections*/metabolism
Humans ; T-Lymphocytes/metabolism ; vpr Gene Products, Human Immunodeficiency Virus/genetics ; vpr Gene Products, Human Immunodeficiency Virus/metabolism ; CD4-Positive T-Lymphocytes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus.
Autorzy:
Joseph SB; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; UNC HIV Cure Center and Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Abrahams MR; Division of Medical Virology, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Moeser M; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Tyers L; Division of Medical Virology, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Archin NM; UNC HIV Cure Center and Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Council OD; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; UNC HIV Cure Center and Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Sondgeroth A; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Spielvogel E; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Emery A; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Zhou S; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Doolabh D; Division of Medical Virology, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Ismail SD; Division of Medical Virology, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Karim SA; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu- Natal, Durban, South Africa.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America.
Margolis DM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; UNC HIV Cure Center and Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Pond SK; Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.
Garrett N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu- Natal, Durban, South Africa.; Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Swanstrom R; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Williamson C; Division of Medical Virology, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu- Natal, Durban, South Africa.; National Health Laboratory Services of South Africa, Johannesburg, South Africa.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Feb 29; Vol. 20 (2), pp. e1011974. Date of Electronic Publication: 2024 Feb 29 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*/genetics
HIV Infections*/drug therapy
Humans ; Proviruses/genetics ; Anti-Retroviral Agents/pharmacology ; Anti-Retroviral Agents/therapeutic use ; CD4-Positive T-Lymphocytes ; DNA, Viral/genetics ; DNA, Viral/metabolism ; Viral Load ; Tropism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV Reservoirs and Treatment Strategies toward Curing HIV Infection.
Autorzy:
Matsuda K; Joint Research Center for Human Retrovirus Infection, Kagoshima University, Kagoshima 890-8544, Japan.; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
Maeda K; Joint Research Center for Human Retrovirus Infection, Kagoshima University, Kagoshima 890-8544, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 23; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Infections*
HIV-1*
Anti-HIV Agents*/pharmacology
Acquired Immunodeficiency Syndrome*/drug therapy
Humans ; Virus Latency ; CD4-Positive T-Lymphocytes ; Virus Activation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Macrophages: Key Cellular Players in HIV Infection and Pathogenesis.
Autorzy:
Woottum M; Institut Cochin, Inserm U1016, CNRS UMR-8104, Université Paris Cité, 75014 Paris, France.
Yan S; Institut Cochin, Inserm U1016, CNRS UMR-8104, Université Paris Cité, 75014 Paris, France.
Sayettat S; Institut Cochin, Inserm U1016, CNRS UMR-8104, Université Paris Cité, 75014 Paris, France.
Grinberg S; CNRS UMR-8601, Université Paris Cité, 75006 Paris, France.
Cathelin D; CNRS UMR-8601, Université Paris Cité, 75006 Paris, France.
Bekaddour N; CNRS UMR-8601, Université Paris Cité, 75006 Paris, France.
Herbeuval JP; CNRS UMR-8601, Université Paris Cité, 75006 Paris, France.
Benichou S; Institut Cochin, Inserm U1016, CNRS UMR-8104, Université Paris Cité, 75014 Paris, France.
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Źródło:
Viruses [Viruses] 2024 Feb 13; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Infections*
Simian Immunodeficiency Virus*
HIV-1*/physiology
HIV Seropositivity*
Humans ; Animals ; Mice ; Macrophages ; Inflammation ; CD4-Positive T-Lymphocytes ; Virus Latency ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dolutegravir based therapy showed CD4 T cell count recovery and viral load suppression among ART naïve people living with HIV AIDS: a pilot evaluation.
Autorzy:
Gebremedhin T; University of Gondar Comprehensive Specialized Hospital, Gondar, Ethiopia.
Aynalem M; Department of Hematology and Immunohematology, University of Gondar, Gondar, Ethiopia.
Adem M; Department of Immunology and Molecular Biology, University of Gondar, Gondar, Ethiopia.
Geremew D; Department of Medical Laboratory Sciences, Immunology and Molecular Biology Unit, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Aleka Y; Department of Immunology and Molecular Biology, University of Gondar, Gondar, Ethiopia. .
Kiflie A; Department of Immunology and Molecular Biology, University of Gondar, Gondar, Ethiopia.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 08; Vol. 14 (1), pp. 3297. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Acquired Immunodeficiency Syndrome*/drug therapy
HIV Infections*
Anti-HIV Agents*/pharmacology
HIV-1*/genetics
Heterocyclic Compounds, 3-Ring*
Oxazines*
Piperazines*
Pyridones*
Humans ; Antiretroviral Therapy, Highly Active ; Prospective Studies ; Viral Load ; Pilot Projects ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes ; RNA/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Canadian Survey of Research on HIV-1 Latency-Where Are We Now and Where Are We Heading?
Autorzy:
Abdalla AL; HIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montreal, QC H3T 1E2, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, QC H3A 2B4, Canada.
Guajardo-Contreras G; HIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montreal, QC H3T 1E2, Canada.; Department of Medicine, McGill University, Montreal, QC H4A 3J1, Canada.
Mouland AJ; HIV-1 RNA Trafficking Laboratory, Lady Davis Institute at the Jewish General Hospital, Montreal, QC H3T 1E2, Canada.; Department of Microbiology and Immunology, McGill University, Montreal, QC H3A 2B4, Canada.; Department of Medicine, McGill University, Montreal, QC H4A 3J1, Canada.
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Źródło:
Viruses [Viruses] 2024 Feb 01; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV-1*
HIV Infections*/drug therapy
HIV Infections*/metabolism
HIV Seropositivity*
Humans ; Virus Latency ; CD4-Positive T-Lymphocytes/metabolism ; Canada ; Virus Activation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV Expression in Infected T Cell Clones.
Autorzy:
Rausch JW; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
Parvez S; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
Pathak S; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
Capoferri AA; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
Kearney MF; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
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Źródło:
Viruses [Viruses] 2024 Jan 11; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Seropositivity*
HIV-1*
Humans ; CD4-Positive T-Lymphocytes ; T-Lymphocytes, Cytotoxic ; Cell Division ; Clone Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells.
Autorzy:
Kobayashi-Ishihara M; Infection Biology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain. .; Department of Molecular Biology, Keio University School of Medicine, Tokyo, Japan. .
Frazão Smutná K; Infection Biology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Alonso FE; Infection Biology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Argilaguet J; Infection Biology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.; Unitat mixta d'Investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; IRTA. Programa de Sanitat Animal. Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.
Esteve-Codina A; Centro Nacional de Análisis Genómico (CNAG-CRG), Center for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona, Spain.
Geiger K; Infection Biology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Genescà M; Infectious Disease Department, Hospital Universitari Vall d´Hebrón, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Grau-Expósito J; Infectious Disease Department, Hospital Universitari Vall d´Hebrón, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Duran-Castells C; IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain.
Rogenmoser S; Infection Biology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Böttcher R; Molecular Virology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Jungfleisch J; Molecular Virology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Oliva B; Structural Bioinformatics Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Martinez JP; Infection Biology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.
Li M; Section of Molecular Biology, Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA.
David M; Section of Molecular Biology, Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.
Yamagishi M; Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.
Ruiz-Riol M; IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain.; CIBER de Enfermedades Infecciosas, Madrid, Spain.
Brander C; IrsiCaixa AIDS Research Institute, Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain.; Universitat de Vic-Universitat Central de Catalunya (UVic-UCC), Vic, Spain.; Institució de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.
Tsunetsugu-Yokota Y; Department of Medical Technology, School of Human Sciences, Tokyo University of Technology, Tokyo, Japan.
Buzon MJ; Infectious Disease Department, Hospital Universitari Vall d´Hebrón, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
Díez J; Molecular Virology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain. .
Meyerhans A; Infection Biology Group, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain. .; Institució de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. .
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Źródło:
Communications biology [Commun Biol] 2023 May 10; Vol. 6 (1), pp. 487. Date of Electronic Publication: 2023 May 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4-Positive T-Lymphocytes*
HIV-1*/physiology
Codon Usage ; RNA, Viral/genetics ; Virus Latency/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characteristics of blood immune cell profile and their correlation with disease progression in patients infected with HIV-1.
Autorzy:
Guo XY; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Qu MM; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Wang X; Clinic of Center for Infection, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China.
Wang ZR; Department of Gastroenterology, First Medical Center of Chinese PLA General Hospital, Beijing, 100853, China.
Song JW; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Yang BP; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Guo YT; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Zhang Y; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Zhang C; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Fan X; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Xu W; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Xu R; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Zhang JY; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Chen SY; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.
Jiao YM; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China. .
Sun LJ; Clinic of Center for Infection, Beijing Youan Hospital, Capital Medical University, Beijing, 100069, China. .
Wang FS; Senior Department of Infectious Diseases, The Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2023 Dec 20; Vol. 23 (1), pp. 893. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*
HIV Infections*
Humans ; CD8-Positive T-Lymphocytes ; RNA ; Disease Progression ; DNA ; CD4-Positive T-Lymphocytes ; Viral Load ; CD4 Lymphocyte Count
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a Cure.
Autorzy:
Duggan NN; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA 92037, USA.
Dragic T; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA 92037, USA.
Chanda SK; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA 92037, USA.
Pache L; NCI Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
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Źródło:
Viruses [Viruses] 2023 Dec 15; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Infections*
HIV Seropositivity*
HIV-1*/physiology
Humans ; Virus Latency ; Virus Replication ; CD4-Positive T-Lymphocytes ; Virus Activation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transient CD4+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice.
Autorzy:
Ling L; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
De C; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Spagnuolo RA; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Begum N; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Falcinelli SD; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Archin NM; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Kovarova M; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Silvestri G; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Wahl A; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Margolis DM; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; UNC HIV Cure Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Garcia JV; International Center for the Advancement of Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Dec 06; Vol. 19 (12), pp. e1011824. Date of Electronic Publication: 2023 Dec 06 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*
HIV-1*
Humans ; Mice ; Animals ; CD4-Positive T-Lymphocytes ; Virus Latency ; Virus Replication ; Anti-Retroviral Agents/pharmacology ; Anti-Retroviral Agents/therapeutic use ; RNA, Viral ; DNA ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size.
Autorzy:
Dwivedi AK; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California, San Francisco, California, United States of America.
Gornalusse GG; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America.
Siegel DA; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California, San Francisco, California, United States of America.
Barbehenn A; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California, San Francisco, California, United States of America.
Thanh C; Department of Medicine, Division of Experimental Medicine, University of California San Francisco, California, United States of America.
Hoh R; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California, San Francisco, California, United States of America.
Hobbs KS; Department of Medicine, Division of Experimental Medicine, University of California San Francisco, California, United States of America.
Pan T; Department of Medicine, Division of Experimental Medicine, University of California San Francisco, California, United States of America.
Gibson EA; Department of Medicine, Division of Experimental Medicine, University of California San Francisco, California, United States of America.
Martin J; Department of Biostatistics & Epidemiology, University of California San Francisco, California, United States of America.
Hecht F; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California, San Francisco, California, United States of America.
Pilcher C; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California, San Francisco, California, United States of America.
Milush J; Department of Medicine, Division of Experimental Medicine, University of California San Francisco, California, United States of America.
Busch MP; Vitalant Blood Bank, San Francisco, California, United States of America.
Stone M; Vitalant Blood Bank, San Francisco, California, United States of America.
Huang ML; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America.
Reppetti J; Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America.; Universidad de Buenos Aires (UBA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO- Houssay), Buenos Aires, Argentina.
Vo PM; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America.
Levy CN; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America.
Roychoudhury P; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America.
Jerome KR; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, United States of America.
Hladik F; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America.; Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, United States of America.
Henrich TJ; Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, United States of America.
Deeks SG; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California, San Francisco, California, United States of America.
Lee SA; Department of Medicine, Division of HIV, Infectious Diseases & Global Medicine, University of California, San Francisco, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Nov 29; Vol. 19 (11), pp. e1011114. Date of Electronic Publication: 2023 Nov 29 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*/genetics
HIV Infections*/drug therapy
HIV Infections*/genetics
Humans ; Interleukin-10 ; Inflammasomes ; CD4-Positive T-Lymphocytes ; Immunity, Innate/genetics ; Genes, Tumor Suppressor ; Gene Expression ; DNA ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cholesterol Metabolism in Antigen-Presenting Cells and HIV-1 Trans-Infection of CD4 T Cells.
Autorzy:
Okpaise D; Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Sluis-Cremer N; Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Rappocciolo G; Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Rinaldo CR; Department of Medicine, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
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Źródło:
Viruses [Viruses] 2023 Nov 29; Vol. 15 (12). Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Review; Journal Article
MeSH Terms:
HIV Infections*/metabolism
HIV-1*/metabolism
Humans ; CD4-Positive T-Lymphocytes/metabolism ; Virus Latency ; Dendritic Cells/metabolism ; Cholesterol/metabolism ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Theoretical study of diffusive model of HIV-1 infection and its analytical solution.
Autorzy:
Aljahdaly NH; Mathematics Department, Faculty of Sciences and Arts, King Abdulaziz University, Rabigh, Saudi Arabia.
Alharbey RA; Department of Mathematics, Faculty of Science, Al-Sulymania Womenans Campus, King AbdulAziz University, Jeddah, Saudi Arabia.
Aljohani AS; Mathematics Department, Faculty of Sciences and Arts, King Abdulaziz University, Rabigh, Saudi Arabia.
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Źródło:
PloS one [PLoS One] 2023 Nov 10; Vol. 18 (11), pp. e0283659. Date of Electronic Publication: 2023 Nov 10 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV-1*
HIV Infections*/therapy
Humans ; Models, Theoretical ; Stem Cell Transplantation ; CD4-Positive T-Lymphocytes ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation.
Autorzy:
Firrito C; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.
Bertelli C; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.
Rosa A; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.
Chande A; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.
Ananth S; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
van Dijk H; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Fackler OT; Department of Infectious Diseases, Integrative Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.; German Center for Infection Research (DZIF), 69120 Heidelberg, Germany.
Stoneham C; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
Singh R; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
Guatelli J; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA.
Pizzato M; Department of Cellular, Computational and integrative Biology, University of Trento, 38123 Trento, Italy.
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Źródło:
Viruses [Viruses] 2023 Feb 28; Vol. 15 (3). Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
CD4-Positive T-Lymphocytes*/immunology
CD4-Positive T-Lymphocytes*/virology
Membrane Proteins*/metabolism
nef Gene Products, Human Immunodeficiency Virus*/chemistry
HIV-1*/pathogenicity
CD4 Antigens*/metabolism
Humans ; Amino Acid Substitution ; HEK293 Cells ; Jurkat Cells ; Amino Acid Sequence ; Endocytosis ; Clathrin ; HIV Infections ; Down-Regulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing.
Autorzy:
Lyons DE; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158, USA.
Kumar P; Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06510, USA.
Roan NR; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158, USA.; Department of Urology, University of California San Francisco, San Francisco, CA 94158, USA.
Defechereux PA; Department of Medicine, University of California San Francisco, San Francisco, CA 94158, USA.
Feschotte C; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
Lange UC; Leibniz Institute of Virology, 20251 Hamburg, Germany.
Murthy N; Department of Bioengineering, University of California, Berkeley, CA 94720, USA.; Innovative Genomics Institute, Berkeley, CA 94720, USA.
Sameshima P; Faculty of Education, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.
Verdin E; Department of Medicine, University of California San Francisco, San Francisco, CA 94158, USA.; Buck Institute for Research on Aging, Novato, CA 94945, USA.
Ake JA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Parsons MS; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20817, USA.; Armed Forces Research Institute of Medical Sciences, Bangkok 10400, Thailand.
Nath A; Section of Infections of the Nervous System, National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20824, USA.
Gianella S; Division of Infectious Diseases, Department of Medicine, University of California San Diego, San Diego, CA 92093, USA.
Smith DM; Division of Infectious Diseases, Department of Medicine, University of California San Diego, San Diego, CA 92093, USA.
Kallas EG; Department of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo 04023-900, Brazil.
Villa TJ; HOPE Martin Delaney Collaboratory for HIV Cure Research Community Engagement Ambassador, Washinton, DC 20004, USA.; National HIV & Aging Advocacy Network, Washington, DC 20004, USA.
Strange R; HOPE Martin Delaney Collaboratory for HIV Cure Research Community Engagement Ambassador, Washinton, DC 20004, USA.
Mwesigwa B; Research Department, Makerere University Walter Reed Project, Kampala P.O Box 7062, Uganda.
Furler O'Brien RL; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.
Nixon DF; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.
Ndhlovu LC; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.
Valente ST; Department of Immunology and Microbiology, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA.
Ott M; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158, USA.; Department of Medicine, University of California San Francisco, San Francisco, CA 94158, USA.
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Źródło:
Viruses [Viruses] 2023 Oct 28; Vol. 15 (11). Date of Electronic Publication: 2023 Oct 28.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*/genetics
Endogenous Retroviruses*
HIV Infections*
HIV Seropositivity*/genetics
Humans ; Virus Latency ; Proviruses/genetics ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Current ART, determinants for virologic failure and implications for HIV drug resistance: an umbrella review.
Autorzy:
SeyedAlinaghi S; Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Afsahi AM; Department of Radiology, School of Medicine, University of California, San Diego (UCSD), San Diego, CA, USA.
Moradi A; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Parmoon Z; Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Habibi P; Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Mirzapour P; Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Dashti M; Department of Radiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Ghasemzadeh A; Department of Radiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Karimi E; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Sanaati F; School of Nursing and Allied Medical Sciences, Maragheh University of Medical Sciences, Maragheh, Iran.
Hamedi Z; Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Molla A; School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.
Mehraeen E; Department of Health Information Technology, Khalkhal University of Medical Sciences, Khalkhal, 5681761351, Iran. .
Dadras O; Bergen Addiction Research, Department of Addiction Medicine, Haukland University Hospital, Bergen, Norway.
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Źródło:
AIDS research and therapy [AIDS Res Ther] 2023 Oct 27; Vol. 20 (1), pp. 74. Date of Electronic Publication: 2023 Oct 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Infections*/drug therapy
HIV Infections*/epidemiology
HIV-1*
Humans ; CD4 Lymphocyte Count ; Treatment Outcome ; CD4-Positive T-Lymphocytes ; Treatment Failure ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mathematical Models of HIV-1 Dynamics, Transcription, and Latency.
Autorzy:
D'Orso I; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Forst CV; Department of Genetics and Genomic Sciences, Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
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Źródło:
Viruses [Viruses] 2023 Oct 19; Vol. 15 (10). Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
HIV-1*/genetics
HIV Infections*/drug therapy
HIV Seropositivity*
Humans ; Virus Latency ; Models, Biological ; Models, Theoretical ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 1122

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