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Tytuł:
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx Digital Spatial Profiler.
Autorzy:
Bergholtz H; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, 0450 Oslo, Norway.
Carter JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
Cesano A; ESSA Pharma Inc., South San Francisco, CA 94080, USA.
Cheang MCU; ICR Clinical Trials and Statistics Unit, Division of Clinical Studies, The Institute of Cancer Research, London SM2 5NG, UK.
Church SE; NanoString® Technologies Inc., Seattle, WA 98109, USA.
Divakar P; NanoString® Technologies Inc., Seattle, WA 98109, USA.
Fuhrman CA; NanoString® Technologies Inc., Seattle, WA 98109, USA.
Goel S; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3010, Australia.
Gong J; NanoString® Technologies Inc., Seattle, WA 98109, USA.
Guerriero JL; Division of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.
Hoang ML; NanoString® Technologies Inc., Seattle, WA 98109, USA.
Hwang ES; Duke Cancer Institute, Duke University, Durham, NC 27710, USA.
Kuasne H; Rosalind and Morris Goodman Cancer Centre, McGill University, Montreal, QC H3A 0G4, Canada.
Lee J; Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA.
Liang Y; NanoString® Technologies Inc., Seattle, WA 98109, USA.
Mittendorf EA; Division of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA.; Breast Oncology Program, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA.
Perez J; NanoString® Technologies Inc., Seattle, WA 98109, USA.
Prat A; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute, 08036 Barcelona, Spain.
Pusztai L; Yale Cancer Center, Yale School of Medicine, New Haven, CT 06510, USA.
Reeves JW; NanoString® Technologies Inc., Seattle, WA 98109, USA.
Riazalhosseini Y; Department of Human Genetics, McGill University, Montreal, QC H3A 0G4, Canada.; McGill University Genome Centre, McGill University, Montreal, QC H3A 0G4, Canada.
Richer JK; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Sahin Ö; Department of Drug Discovery and Biomedical Sciences, University of South Carolina, Columbia, SC 29208, USA.
Sato H; NanoString® Technologies Inc., Seattle, WA 98109, USA.
Schlam I; MedStar Washington Hospital Center, Washington, DC 20010, USA.; Tufts Medical Center, Boston, MA 02111, USA.
Sørlie T; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, 0450 Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, 0315 Oslo, Norway.
Stover DG; Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA.
Swain SM; Georgetown Lombardi Comprehensive Cancer Center, Washington, DC 20057, USA.; Georgetown University Medical Center, Washington, DC 20057, USA.; MedStar Health, Washington, DC 20057, USA.
Swarbrick A; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney NSW 2052, Australia.
Thompson EA; Department of Cancer Biology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Tolaney SM; Harvard Medical School, Boston, MA 02115, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Warren SE; NanoString® Technologies Inc., Seattle, WA 98109, USA.
On Behalf Of The GeoMx Breast Cancer Consortium
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Źródło:
Cancers [Cancers (Basel)] 2021 Sep 04; Vol. 13 (17). Date of Electronic Publication: 2021 Sep 04.
Typ publikacji:
Guideline
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity.
Autorzy:
Ptacek J; Nodality, Inc., South San Francisco, California, United States of America.
Hawtin RE; Nodality, Inc., South San Francisco, California, United States of America.
Sun D; University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America.
Louie B; Nodality, Inc., South San Francisco, California, United States of America.
Evensen E; Nodality, Inc., South San Francisco, California, United States of America.
Mittleman BB; Nodality, Inc., South San Francisco, California, United States of America.
Cesano A; Nodality, Inc., South San Francisco, California, United States of America.
Cavet G; Nodality, Inc., South San Francisco, California, United States of America.
Bingham CO 3rd; Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Cofield SS; University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America.
Curtis JR; University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America.
Danila MI; University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America.
Raman C; University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America.
Furie RA; The Feinstein Institute for Medical Research and Northwell Health, Manhasset, New York, United States of America.
Genovese MC; Stanford University School of Medicine, Stanford, California, United States of America.
Robinson WH; Stanford University School of Medicine, Stanford, California, United States of America.
Levesque MC; Abbvie, Inc., North Chicago, Illinois, United States of America.
Moreland LW; University of Colorado Anschutz Medical Campus, Boulder, Colorado, United States of America.
Nigrovic PA; Brigham and Women's Hospital, Harvard University, Boston, Massachusetts, United States of America.
Shadick NA; Brigham and Women's Hospital, Harvard University, Boston, Massachusetts, United States of America.
O'Dell JR; University of Nebraska Medical Center, Lincoln, Nebraska, United States of America.
Thiele GM; University of Nebraska Medical Center, Lincoln, Nebraska, United States of America.
Clair EWS; Duke University Medical Center, Durham, North Carolina, United States of America.
Striebich CC; University of Colorado Anschutz Medical Campus, Boulder, Colorado, United States of America.
Hale MB; Stanford University School of Medicine, Stanford, California, United States of America.
Khalili H; The Feinstein Institute for Medical Research and Northwell Health, Manhasset, New York, United States of America.
Batliwalla F; The Feinstein Institute for Medical Research and Northwell Health, Manhasset, New York, United States of America.
Aranow C; The Feinstein Institute for Medical Research and Northwell Health, Manhasset, New York, United States of America.
Mackay M; The Feinstein Institute for Medical Research and Northwell Health, Manhasset, New York, United States of America.
Diamond B; The Feinstein Institute for Medical Research and Northwell Health, Manhasset, New York, United States of America.
Nolan GP; Nodality, Inc., South San Francisco, California, United States of America.
Gregersen PK; The Feinstein Institute for Medical Research and Northwell Health, Manhasset, New York, United States of America.
Bridges SL Jr; Hospital for Special Surgery and Weill Cornell Medical College, New York, New York, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Jan 14; Vol. 16 (1), pp. e0244187. Date of Electronic Publication: 2021 Jan 14 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Arthritis, Rheumatoid/*pathology
Interferon-alpha/*pharmacology
Interleukin-10/*pharmacology
STAT1 Transcription Factor/*metabolism
STAT3 Transcription Factor/*metabolism
Signal Transduction/*drug effects
Abatacept/therapeutic use ; Adult ; Aged ; Aged, 80 and over ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/metabolism ; Biomarkers/metabolism ; Case-Control Studies ; Female ; Humans ; Leukocytes, Mononuclear/cytology ; Leukocytes, Mononuclear/metabolism ; Male ; Methotrexate/therapeutic use ; Middle Aged ; Phosphorylation ; Severity of Illness Index
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma.
Autorzy:
Khunger A; Department of Internal Medicine, Memorial Hospital West, Pembroke Pines, Florida, United States of America.
Piazza E; NanoString® Technologies, Inc., Seattle, Washington, United States of America.
Warren S; NanoString® Technologies, Inc., Seattle, Washington, United States of America.
Smith TH; NanoString® Technologies, Inc., Seattle, Washington, United States of America.
Ren X; NanoString® Technologies, Inc., Seattle, Washington, United States of America.
White A; NanoString® Technologies, Inc., Seattle, Washington, United States of America.
Elliott N; NanoString® Technologies, Inc., Seattle, Washington, United States of America.
Cesano A; ESSA Pharma, South San Francisco, California, United States of America.
Beechem JM; NanoString® Technologies, Inc., Seattle, Washington, United States of America.
Kirkwood JM; UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, United States of America.
Tarhini AA; Department of Cutaneous Oncology and Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Jan 11; Vol. 16 (1), pp. e0245287. Date of Electronic Publication: 2021 Jan 11 (Print Publication: 2021).
Typ publikacji:
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Transcription, Genetic*/drug effects
CTLA-4 Antigen/*antagonists & inhibitors
Inflammation/*genetics
Interferon-alpha/*therapeutic use
Melanoma/*immunology
Melanoma/*pathology
Skin Neoplasms/*immunology
Skin Neoplasms/*pathology
CTLA-4 Antigen/metabolism ; Combined Modality Therapy ; Disease-Free Survival ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/drug effects ; Immunotherapy ; Interferon-alpha/pharmacology ; Ipilimumab/therapeutic use ; Melanoma/drug therapy ; Melanoma/genetics ; Neoadjuvant Therapy ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Skin Neoplasms/drug therapy ; Skin Neoplasms/genetics ; Survival Analysis ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Immune profiling of pre- and post-treatment breast cancer tissues from the SWOG S0800 neoadjuvant trial.
Autorzy:
Xiaotong Li
Warren, Sarah
Pelekanou, Vasiliki
Wali, Vikram
Cesano, Alessandra
Liu, Mingdong
Danaher, Patrick
Elliott, Nathane
Nahleh, Zeina A.
Hayes, Daniel F.
Hortobagyi, Gabriel N.
Barlow, William E.
Hatzis, Christos
Pusztai, Lajos
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Źródło:
Journal for ImmunoTherapy of Cancer. 12/1/2019, Vol. 7 Issue 1, p1-9. 9p.
Czasopismo naukowe
Szczegóły
Tytuł:
The tumor inflammation signature (TIS) is associated with anti-PD-1 treatment benefit in the CERTIM pan-cancer cohort.
Autorzy:
Damotte D; Team Cancer, Immune Control and Escape, Cordeliers Research Center, UMRS 1138, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.; University Paris Descartes, Paris, France.; Department of Pathology, Hôpital Cochin, AP-HP, Paris, France.; CERTIM, Hôpital Cochin, APHP, Paris, France.
Warren S; NanoString Technologies, Seattle, WA, USA.
Arrondeau J; CERTIM, Hôpital Cochin, APHP, Paris, France.; Department of Medical Oncology, Hôpital Cochin, AP-HP, Paris, France.
Boudou-Rouquette P; CERTIM, Hôpital Cochin, APHP, Paris, France.; Department of Medical Oncology, Hôpital Cochin, AP-HP, Paris, France.
Mansuet-Lupo A; Team Cancer, Immune Control and Escape, Cordeliers Research Center, UMRS 1138, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.; University Paris Descartes, Paris, France.; Department of Pathology, Hôpital Cochin, AP-HP, Paris, France.; CERTIM, Hôpital Cochin, APHP, Paris, France.
Biton J; Team Physiopathologie, cibles et thérapies de la polyarthrite rhumatoide Laboratoire Immunologie et Immunopathologie-Li2P, UMR1125, Université Paris 13, Bobigny, France.
Ouakrim H; Team Cancer, Immune Control and Escape, Cordeliers Research Center, UMRS 1138, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.; University Paris Descartes, Paris, France.; Department of Pathology, Hôpital Cochin, AP-HP, Paris, France.
Alifano M; Team Cancer, Immune Control and Escape, Cordeliers Research Center, UMRS 1138, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France.; University Paris Descartes, Paris, France.; CERTIM, Hôpital Cochin, APHP, Paris, France.; Department of Thoracic Surgery, Hôpital Cochin, AP-HP, Paris, France.
Gervais C; CERTIM, Hôpital Cochin, APHP, Paris, France.; Department of Medical Oncology, Hôpital Cochin, AP-HP, Paris, France.
Bellesoeur A; CERTIM, Hôpital Cochin, APHP, Paris, France.; Department of Medical Oncology, Hôpital Cochin, AP-HP, Paris, France.
Kramkimel N; CERTIM, Hôpital Cochin, APHP, Paris, France.; Department of Cutaneous Diseases, Hôpital Cochin, AP-HP, Paris, France.
Tlemsani C; CERTIM, Hôpital Cochin, APHP, Paris, France.; Department of Medical Oncology, Hôpital Cochin, AP-HP, Paris, France.
Burroni B; Department of Pathology, Hôpital Cochin, AP-HP, Paris, France.
Duche A; Genomic platform, INSERM U1016, Institut Cochin, Paris, France.
Letourneur F; Genomic platform, INSERM U1016, Institut Cochin, Paris, France.
Si H; Oncology Research, MedImmune, Gaithersburg, MD, USA.
Halpin R; Oncology Research, MedImmune, Gaithersburg, MD, USA.
Creasy T; Oncology Research, MedImmune, Gaithersburg, MD, USA.
Herbst R; Oncology Research, MedImmune, Gaithersburg, MD, USA.
Ren X; NanoString Technologies, Seattle, WA, USA.
Morel P; NanoString Technologies, Seattle, WA, USA.
Cesano A; NanoString Technologies, Seattle, WA, USA.
Goldwasser F; University Paris Descartes, Paris, France.; CERTIM, Hôpital Cochin, APHP, Paris, France.; Department of Medical Oncology, Hôpital Cochin, AP-HP, Paris, France.
Leroy K; University Paris Descartes, Paris, France. .; CERTIM, Hôpital Cochin, APHP, Paris, France. .; Department of Genetic and Molecular Biology, Hôpital Cochin, AP-HP, 27 rue du Faubourg St Jacques, 75014, Paris, France. .
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Źródło:
Journal of translational medicine [J Transl Med] 2019 Nov 04; Vol. 17 (1), pp. 357. Date of Electronic Publication: 2019 Nov 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Inflammation/*genetics
Inflammation/*therapy
Neoplasms/*genetics
Neoplasms/*therapy
Programmed Cell Death 1 Receptor/*antagonists & inhibitors
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/therapy ; Cohort Studies ; Female ; Humans ; Immunotherapy ; Lung Neoplasms/genetics ; Lung Neoplasms/therapy ; Male ; Middle Aged ; Mutation ; Prospective Studies ; Transcriptome ; Translational Research, Biomedical ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 198

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