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Wyszukujesz frazę ""Comet Assay"" wg kryterium: Temat


Tytuł :
Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies.
Autorzy :
Coltman NJ; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom. Electronic address: .
Coke BA; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
Chatzi K; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
Shepherd EL; Centre for Liver and Gastrointestinal Research, Institute of Immunology and Inflammation, and National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, The Medical School, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
Lalor PF; Centre for Liver and Gastrointestinal Research, Institute of Immunology and Inflammation, and National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, The Medical School, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
Schulz-Utermoehl T; Sygnature Discovery, The Discovery Building, BioCity, Pennyfoot Street, Nottingham, United Kingdom.
Hodges NJ; School of Biosciences, University of Birmingham, Birmingham, B15 2TT, United Kingdom. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Jul 01; Vol. 345, pp. 34-45. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Animal Testing Alternatives*
Comet Assay*
4-Nitroquinoline-1-oxide/*toxicity
Anthracenes/*toxicity
Benzo(a)pyrene/*toxicity
Hepatocytes/*drug effects
Imidazoles/*toxicity
Liver/*drug effects
4-Nitroquinoline-1-oxide/metabolism ; Activation, Metabolic ; Anthracenes/metabolism ; Benzo(a)pyrene/metabolism ; DNA Damage ; Gene Expression Regulation, Enzymologic ; Hep G2 Cells ; Hepatocytes/enzymology ; Hepatocytes/pathology ; Histones/metabolism ; Humans ; Imidazoles/metabolism ; Liver/enzymology ; Liver/pathology ; Phosphorylation ; Spheroids, Cellular ; Time Factors
Czasopismo naukowe
Tytuł :
Impact of 12-month cryopreservation on endogenous DNA damage in whole blood and isolated mononuclear cells evaluated by the comet assay.
Autorzy :
Marino M; Division of Human Nutrition, Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133, Milan, Italy.
Gigliotti L; Division of Human Nutrition, Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133, Milan, Italy.
Møller P; Department of Public Health, Section of Environmental Health, University of Copenhagen, 1014, Copenhagen K, Denmark.
Riso P; Division of Human Nutrition, Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133, Milan, Italy.
Porrini M; Division of Human Nutrition, Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133, Milan, Italy.
Del Bo C; Division of Human Nutrition, Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133, Milan, Italy. .
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Źródło :
Scientific reports [Sci Rep] 2021 Jan 11; Vol. 11 (1), pp. 363. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood*
Comet Assay*/methods
Cryopreservation*
Leukocytes, Mononuclear*
Blood Preservation/*adverse effects
Blood Banks/standards ; Blood Preservation/methods ; DNA Breaks ; DNA Damage ; DNA-Formamidopyrimidine Glycosylase/metabolism ; Freezing ; Humans ; Oxidative Stress
Czasopismo naukowe
Tytuł :
B-Comet Assay (Comet Assay on Buccal Cells) for the Evaluation of Primary DNA Damage in Human Biomonitoring Studies.
Autorzy :
Russo C; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
Acito M; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
Fatigoni C; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
Villarini M; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
Moretti M; Department of Pharmaceutical Sciences (Unit of Public Health), University of Perugia, Via del Giochetto, 06122 Perugia, Italy.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Dec 10; Vol. 17 (24). Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Monitoring*/methods
Comet Assay*
DNA Damage*
Lymphocytes*/pathology
Female ; Humans ; Leukocytes/pathology ; Male ; Mouth Mucosa/cytology
Czasopismo naukowe
Tytuł :
Expanded usage of the Challenge-Comet assay as a DNA repair biomarker in human populations: protocols for fresh and cryopreserved blood samples, and for different challenge agents.
Autorzy :
Valdiglesias V; Centro de Investigaciones Científicas Avanzadas (CICA), Departamento de Biología, Facultad de Ciencias, Universidade da Coruña, Grupo DICOMOSA, Campus A Zapateira s/n, 15071, A Coruña, Spain. .; AE CICA-INIBIC. Oza, Instituto de Investigación Biomédica de A Coruña (INIBIC), 15071, A Coruña, Spain. .
Sánchez-Flores M; AE CICA-INIBIC. Oza, Instituto de Investigación Biomédica de A Coruña (INIBIC), 15071, A Coruña, Spain.; Centro de Investigaciones Científicas Avanzadas (CICA), Departamento de Psicología, Facultad de Ciencias de La Educación, Universidade da Coruña, Grupo DICOMOSA, Campus Elviña s/n, 15071, A Coruña, Spain.
Fernández-Bertólez N; AE CICA-INIBIC. Oza, Instituto de Investigación Biomédica de A Coruña (INIBIC), 15071, A Coruña, Spain.; Centro de Investigaciones Científicas Avanzadas (CICA), Departamento de Psicología, Facultad de Ciencias de La Educación, Universidade da Coruña, Grupo DICOMOSA, Campus Elviña s/n, 15071, A Coruña, Spain.
Au W; University of Medicine, Pharmacy, Science and Technology, Gheorghe Marinescu nr. 38, 540139, Targu Mures, Romania.; University of Texas Medical Branch, Galveston, TX, USA.
Pásaro E; AE CICA-INIBIC. Oza, Instituto de Investigación Biomédica de A Coruña (INIBIC), 15071, A Coruña, Spain.; Centro de Investigaciones Científicas Avanzadas (CICA), Departamento de Psicología, Facultad de Ciencias de La Educación, Universidade da Coruña, Grupo DICOMOSA, Campus Elviña s/n, 15071, A Coruña, Spain.
Laffon B; AE CICA-INIBIC. Oza, Instituto de Investigación Biomédica de A Coruña (INIBIC), 15071, A Coruña, Spain.; Centro de Investigaciones Científicas Avanzadas (CICA), Departamento de Psicología, Facultad de Ciencias de La Educación, Universidade da Coruña, Grupo DICOMOSA, Campus Elviña s/n, 15071, A Coruña, Spain.
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Źródło :
Archives of toxicology [Arch Toxicol] 2020 Dec; Vol. 94 (12), pp. 4219-4228. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Monitoring*
Blood Specimen Collection*
Comet Assay*
Cryopreservation*
DNA Damage*
DNA Repair*/drug effects
DNA Repair*/radiation effects
Ultraviolet Rays*
Adult ; Biomarkers/blood ; Bleomycin/toxicity ; Female ; Humans ; Methyl Methanesulfonate/toxicity ; Risk Assessment ; Time Factors ; Young Adult
Czasopismo naukowe
Tytuł :
Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results.
Autorzy :
Møller P; Department of Public Health, Section of Environmental Health, University of Copenhagen, Copenhagen, Denmark. .
Azqueta A; Department of Pharmacology and Toxicology, University of Navarra, Pamplona, Spain.; IdiSNA, Navarra Institute for Health Research, Pamplona, Spain.
Boutet-Robinet E; Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France.
Koppen G; VITO-HEALTH, Mol, Belgium.
Bonassi S; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Pisana, Rome, Italy.; Department of Human Sciences and Quality of Life Promotion, San Raffaele University, Rome, Italy.
Milić M; Mutagenesis Unit, Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Gajski G; Mutagenesis Unit, Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Costa S; Environmental Health Department, National Institute of Health Dr Ricardo Jorge, Porto, Portugal.; Epidemiological Research Unit (EPIUnit), Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.
Teixeira JP; Environmental Health Department, National Institute of Health Dr Ricardo Jorge, Porto, Portugal.; Epidemiological Research Unit (EPIUnit), Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.
Costa Pereira C; Environmental Health Department, National Institute of Health Dr Ricardo Jorge, Porto, Portugal.; Epidemiological Research Unit (EPIUnit), Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.
Dusinska M; Health Effects Laboratory, Department of Environmental Chemistry, Norwegian Institute for Air Research (NILU), Kjeller, Norway.
Godschalk R; Department of Pharmacology & Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, the Netherlands.
Brunborg G; Section of Molecular Toxicology, Department of Environmental Health, Norwegian Institute of Public Health Skøyen, Oslo, Norway.
Gutzkow KB; Section of Molecular Toxicology, Department of Environmental Health, Norwegian Institute of Public Health Skøyen, Oslo, Norway.
Giovannelli L; Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA), Section Pharmacology and Toxicology, University of Florence, Florence, Italy.
Cooke MS; Oxidative Stress Group, Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL, USA.
Richling E; Food Chemistry & Toxicology, Department of Chemistry, University of Kaiserslautern, Kaiserslautern, Germany.
Laffon B; Universidade da Coruña, Grupo DICOMOSA, Centro de Investigaciones Científicas Avanzadas (CICA), Departamento de Psicología, Facultad de Ciencias de la Educación, Coruña, Spain.; Instituto de Investigación Biomédica de A Coruña (INIBIC), AE CICA-INIBIC, Coruña, Spain.
Valdiglesias V; Universidade da Coruña, Grupo DICOMOSA, Centro de Investigaciones Científicas Avanzadas (CICA), Departamento de Psicología, Facultad de Ciencias de la Educación, Coruña, Spain.; Instituto de Investigación Biomédica de A Coruña (INIBIC), AE CICA-INIBIC, Coruña, Spain.
Basaran N; Department of Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Del Bo' C; Division of Human Nutrition, Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, Milan, Italy.
Zegura B; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia.
Novak M; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia.
Stopper H; Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany.
Vodicka P; Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic.; Biomedical Center, Medical Faculty in Pilsen, Charles University in Prague, Prague, Czech Republic.
Vodenkova S; Institute of Experimental Medicine, Czech Academy of Sciences, Prague, Czech Republic.; Biomedical Center, Medical Faculty in Pilsen, Charles University in Prague, Prague, Czech Republic.
de Andrade VM; Laboratory of Translational Biomedicine, University of Southern Santa Catarina, UNESC, Criciúma, Brazil.
Sramkova M; Department of Nanobiology, Cancer Research Institute, Biomedical Research Center of the Slovak Academy of Sciences, Bratislava, Slovakia.
Gabelova A; Department of Nanobiology, Cancer Research Institute, Biomedical Research Center of the Slovak Academy of Sciences, Bratislava, Slovakia.
Collins A; Department of Nutrition, University of Oslo, Oslo, Norway.
Langie SAS; Department of Pharmacology & Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, the Netherlands.; Centre for Environmental Sciences, Hasselt University, Hasselt, Belgium.
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Źródło :
Nature protocols [Nat Protoc] 2020 Dec; Vol. 15 (12), pp. 3817-3826. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Research Design*
Comet Assay/*methods
Comet Assay/standards ; Consensus ; Guideline Adherence/statistics & numerical data ; Humans ; Laboratories
Czasopismo naukowe
Tytuł :
Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells.
Autorzy :
Seo JE; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.
Guo X; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.
Petibone DM; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.
Shelton SD; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.
Chen Y; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.
Li X; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.
Tryndyak V; Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.
Smith-Roe SL; Division of the National Toxicology Program, National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, North Carolina 27709, USA.
Witt KL; Division of the National Toxicology Program, National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, North Carolina 27709, USA.
Mei N; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.
Manjanatha MG; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.
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Źródło :
Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2021 Jul 16; Vol. 182 (1), pp. 96-106.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cimicifuga*
Animals ; Cell Line ; Comet Assay ; DNA Damage ; Humans ; Mice ; Mutagens ; Plant Extracts ; Rats
Czasopismo naukowe
Tytuł :
Cytotoxic, Genotoxic and Senolytic Potential of Native and Micellar Curcumin.
Autorzy :
Beltzig L; Institute of Toxicology, University Medical Center, Obere Zahlbacher Straße 67, 55131 Mainz, Germany.
Frumkina A; Institute of Toxicology, University Medical Center, Obere Zahlbacher Straße 67, 55131 Mainz, Germany.
Schwarzenbach C; Institute of Toxicology, University Medical Center, Obere Zahlbacher Straße 67, 55131 Mainz, Germany.
Kaina B; Institute of Toxicology, University Medical Center, Obere Zahlbacher Straße 67, 55131 Mainz, Germany.
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Źródło :
Nutrients [Nutrients] 2021 Jul 13; Vol. 13 (7). Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
DNA Damage*
Apoptosis/*drug effects
Cellular Senescence/*drug effects
Curcumin/*toxicity
Cell Line, Tumor ; Cell Survival/drug effects ; Comet Assay ; Curcumin/chemistry ; Dose-Response Relationship, Drug ; Drug Compounding ; Ethanol/chemistry ; Humans ; Liposomes ; Micelles ; Necrosis ; Risk Assessment ; Solubility ; Solvents/chemistry
Czasopismo naukowe
Tytuł :
Effect of Coffee and Cocoa-Based Confectionery Containing Coffee on Markers of DNA Damage and Lipid Peroxidation Products: Results from a Human Intervention Study.
Autorzy :
Martini D; Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133 Milan, Italy.
Domínguez-Perles R; Research Group on Quality, Safety, and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
Rosi A; Human Nutrition Unit, Department of Food and Drugs, University of Parma, 43125 Parma, Italy.
Tassotti M; Human Nutrition Unit, Department of Food and Drugs, University of Parma, 43125 Parma, Italy.
Angelino D; Faculty of Bioscience and Technology for Food, Agriculture, and Environment, University of Teramo, 64100 Teramo, Italy.
Medina S; Research Group on Quality, Safety, and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
Ricci C; Pediatric Epidemiology, Department of Pediatrics, University Medicine Leipzig, 04103 Leipzig, Germany.
Guy A; Institut des Biomolécules Max Mousseron, IBMM, University of Montpellier, CNRS, ENSCM, 34093 Montpellier, France.
Oger C; Institut des Biomolécules Max Mousseron, IBMM, University of Montpellier, CNRS, ENSCM, 34093 Montpellier, France.
Gigliotti L; Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133 Milan, Italy.
Durand T; Institut des Biomolécules Max Mousseron, IBMM, University of Montpellier, CNRS, ENSCM, 34093 Montpellier, France.
Marino M; Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133 Milan, Italy.
Gottfried-Genieser H; BIOLOG Life Science Institute, 28199 Bremen, Germany.
Porrini M; Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133 Milan, Italy.
Antonini M; Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Dei Cas A; Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Bonadonna RC; Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Ferreres F; Department of Food Technology and Nutrition, Molecular Recognition and Encapsulation (REM) Group, Universidad Católica de Murcia, UCAM, 30107 Murcia, Spain.
Scazzina F; Human Nutrition Unit, Department of Food and Drugs, University of Parma, 43125 Parma, Italy.
Brighenti F; Human Nutrition Unit, Department of Food and Drugs, University of Parma, 43125 Parma, Italy.
Riso P; Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133 Milan, Italy.
Del Bo' C; Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20133 Milan, Italy.
Mena P; Human Nutrition Unit, Department of Food and Drugs, University of Parma, 43125 Parma, Italy.
Gil-Izquierdo A; Research Group on Quality, Safety, and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC, Espinardo, 30100 Murcia, Spain.
Del Rio D; Human Nutrition Unit, Department of Food and Drugs, University of Parma, 43125 Parma, Italy.
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Źródło :
Nutrients [Nutrients] 2021 Jul 13; Vol. 13 (7). Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Chocolate*/adverse effects
Coffee*/adverse effects
DNA Damage*
Lipid Peroxidation*
Oxidative Stress*
Biomarkers/*blood
8-Hydroxy-2'-Deoxyguanosine/blood ; Chromatography, High Pressure Liquid ; Comet Assay ; Cross-Over Studies ; Cyclic GMP/analogs & derivatives ; Cyclic GMP/blood ; Female ; Guanine/analogs & derivatives ; Guanine/blood ; Humans ; Male ; Tandem Mass Spectrometry ; Young Adult
Czasopismo naukowe
Tytuł :
Use of the alkaline comet assay for monitoring genotoxic effects of arsenic in human populations.
Autorzy :
Qian Q; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, 210023, Nanjing, China.
Chen Y; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, 210023, Nanjing, China.
Wang JQ; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, 210023, Nanjing, China.
Yang DQ; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, 210023, Nanjing, China.
Jiang C; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, 210023, Nanjing, China.
Sun J; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, 210023, Nanjing, China.
Dong J; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, 210023, Nanjing, China. Electronic address: .
Li GC; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, 210023, Nanjing, China. Electronic address: .
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Źródło :
Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2021 Jul; Vol. 867, pp. 503368. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article; Meta-Analysis
MeSH Terms :
Comet Assay/*methods
Mutagens/*toxicity
Arsenic/toxicity ; DNA/metabolism ; DNA Damage ; Humans ; Publications
Czasopismo naukowe
Tytuł :
Mutagenic and genotoxic activities of Phospholipase A 2 Bothropstoxin-I from Bothrops jararacussu in Drosophila melanogaster and human cell lines.
Autorzy :
Naves MPC; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil.
de Morais CR; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil.
de Freitas V; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil.
Ribeiro DL; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
Lopes DS; Multidisciplinary Institute in Health, Federal University of Bahia, Vitória da Conquista, BA, Brazil.
Antunes LMG; Department of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
de Melo Rodrigues V; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil.
de Rezende AAA; Institute of Exact and Natural Sciences of Pontal, Federal University of Uberlândia, Campus Pontal, Ituiutaba, MG, Brazil.
Spanó MA; Institute of Biotechnology, Federal University of Uberlândia, Campus Umuarama, Uberlândia, MG, Brazil. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 01; Vol. 182, pp. 1602-1610. Date of Electronic Publication: 2021 May 24.
Typ publikacji :
Journal Article
MeSH Terms :
Bothrops/*metabolism
Crotalid Venoms/*toxicity
Phospholipases A2/*metabolism
Animals ; Cell Line ; Cell Survival/drug effects ; Comet Assay ; Drosophila melanogaster ; Human Umbilical Vein Endothelial Cells ; Humans ; Mutation/genetics
Czasopismo naukowe
Tytuł :
The screening of the safety profile of polymeric based amoxicillin nanoparticles in various test systems.
Autorzy :
Guncum E; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Kırıkkale University, Kırıkkale, Turkey. Electronic address: .
Bakirel T; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University- Cerrahpasa, Turkey. Electronic address: .
Anlas C; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University- Cerrahpasa, Turkey. Electronic address: .
Isiklan N; Department of Chemistry, Faculty of Science and Arts, Kırıkkale University, Kırıkkale, Turkey. Electronic address: .
Ustun Alkan F; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University- Cerrahpasa, Turkey. Electronic address: .
Charehsaz M; Department of Toxicology, Faculty of Pharmacy, Yeditepe University, Istanbul, Turkey. Electronic address: .
Aydin A; Department of Toxicology, Faculty of Pharmacy, Yeditepe University, Istanbul, Turkey. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2021 Sep 15; Vol. 348, pp. 1-9. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Amoxicillin/*toxicity
Nanoparticles/*toxicity
Animals ; Chickens ; Comet Assay ; DNA Damage ; Drug Delivery Systems ; Drug Evaluation, Preclinical ; Mice ; Polymers ; Salmonella typhimurium/drug effects ; Swiss 3T3 Cells
Czasopismo naukowe
Tytuł :
Toxicological Comparison of Mancozeb and Zoxamide Fungicides at Environmentally Relevant Concentrations by an In Vitro Approach.
Autorzy :
Lori G; Gender-Specific Prevention and Health Unit, Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.; Science Department, Università Degli Studi di Roma Tre, Viale Guglielmo Marconi 446, 00146 Rome, Italy.
Tassinari R; Gender-Specific Prevention and Health Unit, Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Narciso L; Gender-Specific Prevention and Health Unit, Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Udroiu I; Science Department, Università Degli Studi di Roma Tre, Viale Guglielmo Marconi 446, 00146 Rome, Italy.
Sgura A; Science Department, Università Degli Studi di Roma Tre, Viale Guglielmo Marconi 446, 00146 Rome, Italy.
Maranghi F; Gender-Specific Prevention and Health Unit, Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Tait S; Gender-Specific Prevention and Health Unit, Center for Gender-Specific Medicine, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2021 Aug 14; Vol. 18 (16). Date of Electronic Publication: 2021 Aug 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fungicides, Industrial*/toxicity
Maneb*/toxicity
Zineb*/toxicity
Amides ; Comet Assay ; DNA Damage ; Oxidative Stress ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł :
Cytogenotoxicity evaluation of a heavy metal mixture, detected in a polluted urban wetland: Micronucleus and comet induction in the Indian green frog (Euphlyctis hexadactylus) erythrocytes and the Allium cepa bioassay.
Autorzy :
Jayawardena UA; Department of Zoology and Environment Sciences, Faculty of Science, University of Colombo, Colombo 3, Sri Lanka.
Wickramasinghe DD; Department of Zoology and Environment Sciences, Faculty of Science, University of Colombo, Colombo 3, Sri Lanka.
Udagama PV; Department of Zoology and Environment Sciences, Faculty of Science, University of Colombo, Colombo 3, Sri Lanka. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2021 Aug; Vol. 277, pp. 130278. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Metals, Heavy*/analysis
Metals, Heavy*/toxicity
Rana clamitans*
Water Pollutants, Chemical*/analysis
Water Pollutants, Chemical*/toxicity
Animals ; Biological Assay ; Comet Assay ; Ecosystem ; Environmental Monitoring ; Erythrocytes/chemistry ; Onions ; Risk Assessment ; Sri Lanka ; Wetlands
Czasopismo naukowe
Tytuł :
Role of PARP1 on DNA damage induced by mineral silicate chrysotile in bronchial epithelial and pleural mesothelial cells.
Autorzy :
Zhang M; Hangzhou Medical College, Tianmushan Road 182, Zhejiang, 310007, Hangzhou, China.
Xia H; Hangzhou Medical College, Tianmushan Road 182, Zhejiang, 310007, Hangzhou, China.
Yu M; Hangzhou Medical College, Tianmushan Road 182, Zhejiang, 310007, Hangzhou, China.
Ju L; Hangzhou Medical College, Tianmushan Road 182, Zhejiang, 310007, Hangzhou, China.
Xiao Y; Hangzhou Medical College, Tianmushan Road 182, Zhejiang, 310007, Hangzhou, China.
Zhu L; Hangzhou Medical College, Tianmushan Road 182, Zhejiang, 310007, Hangzhou, China. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Aug; Vol. 28 (30), pp. 40871-40878. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Asbestos, Serpentine*/toxicity
DNA Damage*
Bronchi ; Comet Assay ; DNA Repair ; Epithelial Cells
Czasopismo naukowe
Tytuł :
In vitro effects of harmine against Echinococcus granulosus protoscoleces by stimulating DNA damage.
Autorzy :
Lu S; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, PR China; Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science Nanjing Normal University, Nanjing, Jiangsu, PR China.
Wen L; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, PR China; College of Pharmacy, Xinjiang Medical University, Urumqi, Xinjiang, PR China.
Gong Y; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, PR China.
Tian C; College of Pharmacy, Xinjiang Medical University, Urumqi, Xinjiang, PR China.
Gao H; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, PR China.
Chen B; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, PR China.
Lü G; Xinjiang Key Laboratory of Echinococcosis, Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, Xinjiang, PR China.
Zhao J; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, PR China. Electronic address: .
Wang J; Department of Pharmacy, The First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, PR China; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, PR China. Electronic address: .
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Źródło :
Experimental parasitology [Exp Parasitol] 2021 Jul-Aug; Vol. 226-227, pp. 108121. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article
MeSH Terms :
Antiparasitic Agents/*pharmacology
DNA Damage/*drug effects
Echinococcosis/*drug therapy
Echinococcus granulosus/*drug effects
Harmine/*pharmacology
Animals ; Antiparasitic Agents/therapeutic use ; Comet Assay ; Echinococcus granulosus/genetics ; Echinococcus granulosus/ultrastructure ; Harmine/therapeutic use ; Microscopy, Electron, Transmission ; Monoamine Oxidase Inhibitors/pharmacology ; RNA, Small Interfering/chemistry ; RNA, Small Interfering/physiology ; Real-Time Polymerase Chain Reaction ; Sheep
Czasopismo naukowe
Tytuł :
Genotoxicity Study of Vitex megapotamica (Spreng.) Moldenke.
Autorzy :
Ribeiro RCL; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Botelho ELL; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Donadel G; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Ames ML; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Nunes B; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Tramontini S; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Soares AA; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Alberton O; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Jacomassi E; Laboratory of Pre-Clinical Research of Natural Products, Post-Graduation Program in Animal Science with Emphasis on Bioactive Products, Universidade Paranaense, Umuarama, PR, Brazil.
Gasparotto Junior A; Laboratory of Cardiovascular Pharmacology (LaFaC), Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil.
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Źródło :
Journal of medicinal food [J Med Food] 2021 Jul; Vol. 24 (7), pp. 762-765. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article
MeSH Terms :
Vitex*
Animals ; Brazil ; Comet Assay ; DNA Damage ; Micronucleus Tests ; Plant Extracts/toxicity ; Plant Leaves ; Rats
Czasopismo naukowe
Tytuł :
Revisiting the evidence for genotoxicity of acrylamide (AA), key to risk assessment of dietary AA exposure.
Autorzy :
Eisenbrand G; University of Kaiserslautern, Germany (Retired), Kühler Grund 48/1, 69126, Heidelberg, Germany. .
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Źródło :
Archives of toxicology [Arch Toxicol] 2020 Sep; Vol. 94 (9), pp. 2939-2950. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Comet Assay*
Dietary Exposure*
Acrylamide/*toxicity
Carcinogens/*toxicity
Animals ; Hepatocytes ; Humans ; Male ; Rats
Czasopismo naukowe
Tytuł :
Applications of CometChip for Environmental Health Studies.
Autorzy :
Chao C; Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
Engelward BP; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2020 Jul 20; Vol. 33 (7), pp. 1528-1538. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Comet Assay*
Environmental Health*
DNA/*analysis
Animals ; DNA Damage ; Humans
Czasopismo naukowe
Tytuł :
Comet Assay Evaluation of Lanthanum Nitrate DNA Damage in C57-ras Transgenic Mice.
Autorzy :
Han G; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China.
Tan Z; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.
Jing H; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China.
Ning J; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China.
Li Z; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China.
Gao S; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.
Li G; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China. .; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China. .
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Źródło :
Biological trace element research [Biol Trace Elem Res] 2021 Oct; Vol. 199 (10), pp. 3728-3736. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
Lanthanum*/toxicity
Animals ; Comet Assay ; Humans ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Evaluation of DNA damage and toxicological methodology development: A bibliometric study.
Autorzy :
Nascimento FA; Laboratório de Mutagênese (LabMut), Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Silva DME; Laboratório de Mutagênese (LabMut), Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Nunes HF; Laboratório de Mutagênese (LabMut), Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Parise MR; Laboratório de Mutagênese (LabMut), Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Brazil.
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Źródło :
Human & experimental toxicology [Hum Exp Toxicol] 2020 Jun; Vol. 39 (6), pp. 870-880. Date of Electronic Publication: 2020 Feb 07.
Typ publikacji :
Journal Article
MeSH Terms :
Comet Assay*
DNA Damage*
Bibliometrics ; Databases, Factual ; Toxicology/methods
Czasopismo naukowe

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