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Tytuł:
Short- and long-term reproducibility of the COMET assay for measuring DNA damage biomarkers in frozen blood samples of the EPIC-Heidelberg cohort.
Autorzy:
Bankoglu EE; Institute of Pharmacology and Toxicology, University of Wuerzburg, Wuerzburg, Germany.
Mukama T; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Katzke V; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Stipp F; Institute of Pharmacology and Toxicology, University of Wuerzburg, Wuerzburg, Germany.
Johnson T; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Kühn T; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Institute for Global Food Security, Queen's University Belfast, Belfast, BT9 5DL, UK.
Seyfried F; Department of General, Vascular, Visceral and Paediatric Surgery, University Hospital of Wuerzburg, Wuerzburg, Germany.
Godschalk R; Department of Pharmacology & Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, the Netherlands.
Collins A; Department of Nutrition, University of Oslo, Oslo, Norway.
Kaaks R; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Stopper H; Institute of Pharmacology and Toxicology, University of Wuerzburg, Wuerzburg, Germany. Electronic address: .
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Źródło:
Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2022 Feb-Mar; Vol. 874-875, pp. 503442. Date of Electronic Publication: 2022 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Comet Assay*
Cryopreservation*
DNA Damage*
Leukocytes, Mononuclear*
Biomarkers ; Humans ; Obesity, Morbid/blood ; Prospective Studies ; Reproducibility of Results ; Retrospective Studies
Czasopismo naukowe
Szczegóły
Tytuł:
Determination of genotoxic damages of picloram and dicamba with comet assay in Allium cepa rooted in tissue culture and distilled water.
Autorzy:
Ozel CA; Faculty of Gazi Education, Department of Biology Education, Gazi University, Ankara, Turkey. .
Unal F; Science Faculty, Department of Biology, Gazi University, Ankara, Turkey.
Avuloglu-Yilmaz E; Vocational School of Technical Sciences, Amasya University, Amasya, Turkey.
Erikel E; Science Faculty, Department of Biology, Gazi University, Ankara, Turkey.
Mirici S; Faculty of Gazi Education, Department of Biology Education, Gazi University, Ankara, Turkey.
Yuzbasioglu D; Science Faculty, Department of Biology, Gazi University, Ankara, Turkey.
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Źródło:
Molecular biology reports [Mol Biol Rep] 2022 Dec; Vol. 49 (12), pp. 11273-11280. Date of Electronic Publication: 2022 Jul 08.
Typ publikacji:
Journal Article
MeSH Terms:
Onions*/genetics
Dicamba*/pharmacology
Comet Assay ; Picloram/pharmacology ; Ecosystem ; Chromosome Aberrations/chemically induced ; DNA Damage ; Water
Czasopismo naukowe
Szczegóły
Tytuł:
Relationship between DNA damage measured by the comet-assay and cognitive function.
Autorzy:
Lorenzo-López L; Universidade da Coruña, Gerontology and Geriatrics Research Group, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Servizo Galego de Saúde (SERGAS), A Coruña, Spain.
Lema-Arranz C; Universidade da Coruña, Grupo NanoToxGen, CICA - Centro Interdisciplinar de Química e Bioloxía, Departamento de Biología, A Coruña, Spain; Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain; Universidade da Coruña, Grupo DICOMOSA, CICA - Centro Interdisciplinar de Química e Bioloxía, Departamento de Psicología, A Coruña, Spain.
Fernández-Bertólez N; Universidade da Coruña, Grupo NanoToxGen, CICA - Centro Interdisciplinar de Química e Bioloxía, Departamento de Biología, A Coruña, Spain; Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain.
Costa S; Department of Environmental Health, Portuguese National Institute of Health, Porto, Portugal; EPIUnit-Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal; Laboratório para a Investigação Integrativa e Translacional em Saúde Populacional (ITR), Porto, Portugal.
Costa C; Department of Environmental Health, Portuguese National Institute of Health, Porto, Portugal; EPIUnit-Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal; Laboratório para a Investigação Integrativa e Translacional em Saúde Populacional (ITR), Porto, Portugal.
Teixeira JP; Department of Environmental Health, Portuguese National Institute of Health, Porto, Portugal; EPIUnit-Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal; Laboratório para a Investigação Integrativa e Translacional em Saúde Populacional (ITR), Porto, Portugal.
Pásaro E; Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain; Universidade da Coruña, Grupo DICOMOSA, CICA - Centro Interdisciplinar de Química e Bioloxía, Departamento de Psicología, A Coruña, Spain.
Valdiglesias V; Universidade da Coruña, Grupo NanoToxGen, CICA - Centro Interdisciplinar de Química e Bioloxía, Departamento de Biología, A Coruña, Spain; Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain. Electronic address: .
Laffon B; Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain; Universidade da Coruña, Grupo DICOMOSA, CICA - Centro Interdisciplinar de Química e Bioloxía, Departamento de Psicología, A Coruña, Spain.
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Źródło:
Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2022 Nov-Dec; Vol. 883-884, pp. 503557. Date of Electronic Publication: 2022 Oct 07.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Cognitive Dysfunction*/genetics
Animals ; Humans ; Female ; Pregnancy ; Comet Assay ; Cognition ; Genomic Instability
Czasopismo naukowe
Szczegóły
Tytuł:
Cell survival after DNA damage in the comet assay.
Autorzy:
Bankoglu EE; Institute of Pharmacology and Toxicology, University of Wuerzburg, Versbacher Straße 9, 97078, Wuerzburg, Germany.
Schuele C; Institute of Pharmacology and Toxicology, University of Wuerzburg, Versbacher Straße 9, 97078, Wuerzburg, Germany.
Stopper H; Institute of Pharmacology and Toxicology, University of Wuerzburg, Versbacher Straße 9, 97078, Wuerzburg, Germany. .
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Źródło:
Archives of toxicology [Arch Toxicol] 2021 Dec; Vol. 95 (12), pp. 3803-3813. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji:
Journal Article
MeSH Terms:
Comet Assay*
Apoptosis/*drug effects
Cell Survival/*drug effects
DNA Damage/*drug effects
Antineoplastic Agents, Alkylating/administration & dosage ; Antineoplastic Agents, Alkylating/toxicity ; Cell Line ; Cell Proliferation/drug effects ; DNA Repair/drug effects ; Dose-Response Relationship, Drug ; Etoposide/administration & dosage ; Etoposide/toxicity ; Humans ; Hydrogen Peroxide/administration & dosage ; Hydrogen Peroxide/toxicity ; Methyl Methanesulfonate/administration & dosage ; Methyl Methanesulfonate/toxicity ; Oxidants/administration & dosage ; Oxidants/toxicity ; Time Factors ; Topoisomerase II Inhibitors/administration & dosage ; Topoisomerase II Inhibitors/toxicity
Czasopismo naukowe
Szczegóły
Tytuł:
Cytotoxic and genotoxic evaluation of bisphenol S on onion root tips by Allium cepa and comet tests.
Autorzy:
Ali MM; Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan. .
Fatima A; Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
Nawaz S; Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
Rehman A; Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
Javed M; Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
Nadeem A; Department of Biotechnology, Virtual University of Pakistan, Lahore, 54000, Pakistan.
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Źródło:
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2022 Dec; Vol. 29 (59), pp. 88803-88811. Date of Electronic Publication: 2022 Jul 15.
Typ publikacji:
Journal Article
MeSH Terms:
Onions*
Meristem*
Rats ; Mice ; Animals ; Comet Assay ; Zebrafish/genetics ; Plant Roots ; DNA Damage ; Mitotic Index ; Chromosome Aberrations/chemically induced
Czasopismo naukowe
Szczegóły
Tytuł:
Genotoxicity testing of nanomaterials.
Autorzy:
Landsiedel R; Experimental Toxicology and Ecology, BASF SE, Ludwigshafen am Rhein, Germany.; Pharmacy, Pharmacology and Toxicology, Free University of Berlin, Berlin, Germany.
Honarvar N; Experimental Toxicology and Ecology, BASF SE, Ludwigshafen am Rhein, Germany.
Seiffert SB; Competence Center Analytics, BASF SE, Ludwigshafen am Rhein, Germany.
Oesch B; Oesch-Tox Toxicological Consulting and Expert Opinions, GmbH & Co KG, Ingelheim, Germany.
Oesch F; Oesch-Tox Toxicological Consulting and Expert Opinions, GmbH & Co KG, Ingelheim, Germany.; Institute of Toxicology, Johannes Gutenberg University, Mainz, Germany.
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Źródło:
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology [Wiley Interdiscip Rev Nanomed Nanobiotechnol] 2022 Nov; Vol. 14 (6), pp. e1833.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Nanostructures*/toxicity
Mice ; Humans ; Animals ; Mutagenicity Tests ; Comet Assay ; Micronucleus Tests ; Chromosome Aberrations/chemically induced ; Mammals
Czasopismo naukowe
Szczegóły
Tytuł:
Association between lead exposure and DNA damage (genotoxicity): systematic review and meta-analysis.
Autorzy:
Nagaraju R; Biochemistry, Regional Occupational Health Centre (Southern), ICMR-National Institute of Occupational Health, Bengaluru, Karnataka, India.
Kalahasthi R; Biochemistry, Regional Occupational Health Centre (Southern), ICMR-National Institute of Occupational Health, Bengaluru, Karnataka, India.
Balachandar R; Division of Health Sciences, ICMR-National Institute of Occupational Health, Ahmedabad, Gujarat, India.
Bagepally BS; Non-Communicable Diseases, ICMR-National Institute of Epidemiology, Tamil Nadu, Chennai, India. .
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Źródło:
Archives of toxicology [Arch Toxicol] 2022 Nov; Vol. 96 (11), pp. 2899-2911. Date of Electronic Publication: 2022 Aug 05.
Typ publikacji:
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms:
Lead*/analysis
Lead*/toxicity
Occupational Exposure*/adverse effects
Occupational Exposure*/analysis
8-Hydroxy-2'-Deoxyguanosine ; Biomarkers ; Chromosome Aberrations/chemically induced ; Comet Assay ; DNA ; DNA Damage ; Humans ; Micronucleus Tests/methods
Czasopismo naukowe
Szczegóły
Tytuł:
Cytogenotoxicity assessment of 3-(3,4-dihydroxyphenyl)-7,8-dihydroxycoumarin on HepG2/C3A cells and leukocytes.
Autorzy:
Castanha APM; Marilia Medical School, FAMEMA, Marilia, Brazil.
Almeida-Terassi LM; Marilia Medical School, FAMEMA, Marilia, Brazil.
Guardado-Yordi E; Universidad Estatal Amazonica, Puyo, Ecuador.
Matos MJ; Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal.
Maistro EL; Marilia Medical School, FAMEMA, Marilia, Brazil.; Faculty of Philosophy and Sciences, Speech and Hearing Therapy Department, São Paulo State University-UNESP, Marília, Brazil.
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Źródło:
Journal of applied toxicology : JAT [J Appl Toxicol] 2023 Feb; Vol. 43 (2), pp. 323-334. Date of Electronic Publication: 2022 Sep 02.
Typ publikacji:
Journal Article
MeSH Terms:
Leukocytes, Mononuclear*
Leukocytes*
Humans ; Comet Assay ; Umbelliferones/toxicity ; DNA Damage ; Micronucleus Tests ; Mutagens
Czasopismo naukowe
Szczegóły
Tytuł:
Factors associated with genetic damage - an analysis integrating human populations from Southern Brazil.
Autorzy:
Tavella RA; Programa de Pós-Graduação Em Ciências da Saúde, Faculdade de Medicina, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil.; Laboratório de Ensaios Farmacológicos E Toxicológicos, Instituto de Ciências Biológicas, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil.
Fernandes CLF; Programa de Pós-Graduação Em Ciências da Saúde, Faculdade de Medicina, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil.; Laboratório de Ensaios Farmacológicos E Toxicológicos, Instituto de Ciências Biológicas, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil.
Schimith LE; Programa de Pós-Graduação Em Ciências da Saúde, Faculdade de Medicina, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil.
Volcão LM; Programa de Pós-Graduação Em Ciências da Saúde, Faculdade de Medicina, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil.; Laboratório de Ensaios Farmacológicos E Toxicológicos, Instituto de Ciências Biológicas, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil.
Dos Santos M; Programa de Pós-Graduação Em Ciências da Saúde, Faculdade de Medicina, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil.; Laboratório de Ensaios Farmacológicos E Toxicológicos, Instituto de Ciências Biológicas, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil.
da Silva Júnior FMR; Programa de Pós-Graduação Em Ciências da Saúde, Faculdade de Medicina, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil. .; Laboratório de Ensaios Farmacológicos E Toxicológicos, Instituto de Ciências Biológicas, Universidade Federal Do Rio Grande - FURG, Rio Grande, Brazil. .
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Źródło:
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2022 Oct; Vol. 29 (49), pp. 74335-74345. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Occupational Exposure*
Brazil ; Comet Assay ; Humans ; Micronucleus Tests/methods
Czasopismo naukowe
Szczegóły
Tytuł:
The effect of low doses of chlorpyrifos on blood and bone marrow cells in Wistar rats.
Autorzy:
Kašuba V; Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Micek V; Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Milić M; Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Želježić D; Institute for Medical Research and Occupational Health, Zagreb, Croatia.
Katić A; Institute for Medical Research and Occupational Health, Zagreb, Croatia.
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Źródło:
Arhiv za higijenu rada i toksikologiju [Arh Hig Rada Toksikol] 2022 Sep 30; Vol. 73 (3), pp. 223-232. Date of Electronic Publication: 2022 Sep 30 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Chlorpyrifos*/toxicity
Animals ; Body Weight ; Bone Marrow Cells ; Comet Assay/methods ; DNA Damage ; Male ; Methane ; Micronucleus Tests/methods ; Rats ; Rats, Wistar
Czasopismo naukowe
Szczegóły
Tytuł:
Investigation of the Genotoxic Potential of the Marine Toxin C17-SAMT Using the In Vivo Comet and Micronucleus Assays.
Autorzy:
Marzougui Z; Laboratoire des Venins et Biomolécules Thérapeutiques, Institut Pasteur de Tunis, Université Tunis El Manar, 13 Place Pasteur, B.P. 74, Tunis-Belvédère, Tunis 1002, Tunisia.; National Institute of Agronomy, University of Carthage, Tunis 1082, Tunisia.
Huet S; Unité de Toxicologie des Contaminants, Agence Nationale de Sécurité Sanitaire (ANSES), 10 B rue Claude Bourgelat, 35306 Fougères, France.
Blier AL; Unité de Toxicologie des Contaminants, Agence Nationale de Sécurité Sanitaire (ANSES), 10 B rue Claude Bourgelat, 35306 Fougères, France.
Hégarat LL; Unité de Toxicologie des Contaminants, Agence Nationale de Sécurité Sanitaire (ANSES), 10 B rue Claude Bourgelat, 35306 Fougères, France.
Tounsi-Kettiti H; Laboratoire d'Anatomie Pathologique Humaine et Expérimentale, Institut Pasteur de Tunis, Université Tunis El Manar, 13 Place Pasteur, B.P. 74, Tunis-Belvédère, Tunis 1002, Tunisia.
Kharrat R; Laboratoire des Venins et Biomolécules Thérapeutiques, Institut Pasteur de Tunis, Université Tunis El Manar, 13 Place Pasteur, B.P. 74, Tunis-Belvédère, Tunis 1002, Tunisia.
Marrouchi R; Laboratoire des Venins et Biomolécules Thérapeutiques, Institut Pasteur de Tunis, Université Tunis El Manar, 13 Place Pasteur, B.P. 74, Tunis-Belvédère, Tunis 1002, Tunisia.
Fessard V; Unité de Toxicologie des Contaminants, Agence Nationale de Sécurité Sanitaire (ANSES), 10 B rue Claude Bourgelat, 35306 Fougères, France.
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Źródło:
Marine drugs [Mar Drugs] 2022 Sep 30; Vol. 20 (10). Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Mycotoxins*/toxicity
Mice ; Humans ; Animals ; Comet Assay ; Micronucleus Tests ; Neurotoxins ; DNA Damage ; Marine Toxins/toxicity ; Alkalies
Czasopismo naukowe
Szczegóły
Tytuł:
In vitro evaluation of zearalenone toxicity by comet assay.
Autorzy:
Harcarova M; Department of Animal Nutrition and Husbandry, University of Veterinary Medicine and Pharmacy in Kosice, Komenskeho 73, 041 81 Kosice, Slovak Republic.
Conkova E; Department of Pharmacology and Toxicology, University of Veterinary Medicine and Pharmacy in Kosice, Komenskeho 73, 041 81 Kosice, Slovak Republic.
Kolenicova S; Department of Biology and Physiology, University of Veterinary Medicine and Pharmacy in Kosice, Komenskeho 73, 041 81 Kosice, Slovak Republic.
Holeckova B; Department of Biology and Physiology, University of Veterinary Medicine and Pharmacy in Kosice, Komenskeho 73, 041 81 Kosice, Slovak Republic.
Proskovcova M; Department of Pharmacology and Toxicology, University of Veterinary Medicine and Pharmacy in Kosice, Komenskeho 73, 041 81 Kosice, Slovak Republic.
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Źródło:
Polish journal of veterinary sciences [Pol J Vet Sci] 2022 Sep; Vol. 25 (3), pp. 475-477.
Typ publikacji:
Journal Article
MeSH Terms:
Zearalenone*/toxicity
Animals ; Cattle ; Comet Assay/veterinary ; DNA Damage ; Lymphocytes
Czasopismo naukowe
Szczegóły
Tytuł:
Evaluating nanobiomaterial-induced DNA strand breaks using the alkaline comet assay.
Autorzy:
Tutty MA; Nanomedicine and Molecular Imaging Group, Clinical Medicine, Trinity Translational Medicine Institute (TTMI), Trinity College Dublin, St James's Hospital, Dublin 8, Ireland. .; Laboratory for Biological Characterization of Advanced Materials (LBCAM), TTMI, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland. .
Vella G; Nanomedicine and Molecular Imaging Group, Clinical Medicine, Trinity Translational Medicine Institute (TTMI), Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.; Laboratory for Biological Characterization of Advanced Materials (LBCAM), TTMI, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.
Vennemann A; IBE R&D Institute for Lung Health gGmbH, Münster, Germany.
Wiemann M; IBE R&D Institute for Lung Health gGmbH, Münster, Germany.
Prina-Mello A; Nanomedicine and Molecular Imaging Group, Clinical Medicine, Trinity Translational Medicine Institute (TTMI), Trinity College Dublin, St James's Hospital, Dublin 8, Ireland. .; Laboratory for Biological Characterization of Advanced Materials (LBCAM), TTMI, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland. .; Trinity St James's Cancer Institute, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland. .
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Źródło:
Drug delivery and translational research [Drug Deliv Transl Res] 2022 Sep; Vol. 12 (9), pp. 2243-2258. Date of Electronic Publication: 2022 May 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gold*
Metal Nanoparticles*/toxicity
Comet Assay/methods ; DNA ; DNA Damage
Czasopismo naukowe
Szczegóły
Tytuł:
Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?
Autorzy:
Azqueta A; Department of Pharmacology and Toxicology, University of Navarra, C/Irunlarrea 1, 31009 Pamplona, Spain and IdiSNA, Navarra Institute for Health Research, Pamplona, Spain. Electronic address: .
Stopper H; Institute of Pharmacology and Toxicology, University of Würzburg, Versbacher Str. 9, 97078 Würzburg, Germany.
Zegura B; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna pot 111, 1000 Ljubljana, Slovenia.
Dusinska M; Health Effects Laboratory, Department of Environmental Chemistry, NILU-Norwegian Institute for Air Research, Instituttveien 18, 2002 Kjeller, Norway.
Møller P; Department of Public Health, Section of Environmental Health, University of Copenhagen, Øster Farimagsgade 5A, DK-1014 Copenhagen, Denmark.
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Źródło:
Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2022 Sep; Vol. 881, pp. 503520. Date of Electronic Publication: 2022 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Mutagens*
Cause of Death ; Cell Death ; Comet Assay
Czasopismo naukowe
Szczegóły
Tytuł:
General toxicity and genotoxicity of altertoxin I: A novel 28-day multiendpoint assessment in male Sprague-Dawley rats.
Autorzy:
Zhu X; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, China.
Chen Y; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, China.
Tang X; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, China.
Wang D; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, China.
Miao Y; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, China.
Zhang J; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, China.
Li R; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, China.
Zhang L; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, China.
Chen J; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu, China.
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Źródło:
Journal of applied toxicology : JAT [J Appl Toxicol] 2022 Aug; Vol. 42 (8), pp. 1310-1322. Date of Electronic Publication: 2022 Feb 13.
Typ publikacji:
Journal Article; Randomized Controlled Trial, Veterinary; Research Support, Non-U.S. Gov't
MeSH Terms:
Mycotoxins*
Perylene*/analogs & derivatives
Perylene*/toxicity
Animals ; Comet Assay ; DNA Damage ; Male ; Micronucleus Tests ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Szczegóły
Tytuł:
Novel In Vivo CometChip Reveals NDMA-Induced DNA Damage and Repair in Multiple Mouse Tissues.
Autorzy:
Owiti NA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Corrigan JJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Pribyl LJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Kay JE; Silent Spring Institute, Newton, MA 02460, USA.
Engelward BP; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 04; Vol. 23 (19). Date of Electronic Publication: 2022 Oct 04.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Glycosylases*
Dimethylnitrosamine*
Alkalies ; Animals ; Comet Assay/methods ; DNA ; DNA Damage ; DNA Repair ; Methyl Methanesulfonate ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
High anesthetic (isoflurane) indoor pollution is associated with genetic instability, cytotoxicity, and proliferative alterations in professionals working in a veterinary hospital.
Autorzy:
Figueiredo DBS; GENOTOX Laboratory, Botucatu Medical School, São Paulo State University - UNESP, Prof. Mario Rubens G. Montenegro Av., Botucatu, 18618-687, Brazil.
Aun AG; GENOTOX Laboratory, Botucatu Medical School, São Paulo State University - UNESP, Prof. Mario Rubens G. Montenegro Av., Botucatu, 18618-687, Brazil.
Souza KM; GENOTOX Laboratory, Botucatu Medical School, São Paulo State University - UNESP, Prof. Mario Rubens G. Montenegro Av., Botucatu, 18618-687, Brazil.
Nishimoto IH; GENOTOX Laboratory, Botucatu Medical School, São Paulo State University - UNESP, Prof. Mario Rubens G. Montenegro Av., Botucatu, 18618-687, Brazil.
Silva MAP; GENOTOX Laboratory, Botucatu Medical School, São Paulo State University - UNESP, Prof. Mario Rubens G. Montenegro Av., Botucatu, 18618-687, Brazil.
de Carvalho LR; Institute of Biosciences, São Paulo State University - UNESP, 250, Prof. Dr. Antônio Celso Wagner Zanin, Botucatu, 18618-689, Brazil.
Braz LG; GENOTOX Laboratory, Botucatu Medical School, São Paulo State University - UNESP, Prof. Mario Rubens G. Montenegro Av., Botucatu, 18618-687, Brazil.
Braz MG; GENOTOX Laboratory, Botucatu Medical School, São Paulo State University - UNESP, Prof. Mario Rubens G. Montenegro Av., Botucatu, 18618-687, Brazil. .
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Źródło:
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2022 Oct; Vol. 29 (47), pp. 71774-71784. Date of Electronic Publication: 2022 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Air Pollution, Indoor*
Anesthetics, Inhalation*
Isoflurane*
Occupational Exposure*/analysis
Animals ; Comet Assay ; DNA Damage ; Female ; Hospitals, Animal ; Humans ; Male ; Micronucleus Tests/methods
Czasopismo naukowe
Szczegóły
Tytuł:
Lack of mutagenicity of TiO 2 nanoparticles in vitro despite cellular and nuclear uptake.
Autorzy:
El Yamani N; Health Effects Laboratory, Department for Environmental Chemistry, NILU - Norwegian Institute for Air Research, Kjeller, Norway.
Rubio L; Department of Genetics and Microbiology, Faculty of Biosciences, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès (Barcelona), Spain.
García-Rodríguez A; Department of Genetics and Microbiology, Faculty of Biosciences, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès (Barcelona), Spain.
Kažimírová A; Department of Biology, Faculty of Medicine, Slovak Medical University, 833 03 Bratislava, Slovakia.
Rundén-Pran E; Health Effects Laboratory, Department for Environmental Chemistry, NILU - Norwegian Institute for Air Research, Kjeller, Norway.
Magdalena B; Department of Biology, Faculty of Medicine, Slovak Medical University, 833 03 Bratislava, Slovakia.
Marcos R; Department of Genetics and Microbiology, Faculty of Biosciences, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès (Barcelona), Spain. Electronic address: .
Dusinska M; Health Effects Laboratory, Department for Environmental Chemistry, NILU - Norwegian Institute for Air Research, Kjeller, Norway. Electronic address: .
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Źródło:
Mutation research. Genetic toxicology and environmental mutagenesis [Mutat Res Genet Toxicol Environ Mutagen] 2022 Oct; Vol. 882, pp. 503545. Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Journal Article
MeSH Terms:
Metal Nanoparticles*/toxicity
Nanoparticles*/toxicity
Comet Assay ; DNA ; DNA Damage ; Hypoxanthine Phosphoribosyltransferase/genetics ; Mutagenicity Tests ; Mutagens/toxicity ; Purines ; Titanium/toxicity
Czasopismo naukowe
Szczegóły
Tytuł:
Cyto-Genotoxicity of Tritiated Stainless Steel and Cement Particles in Human Lung Cell Models.
Autorzy:
Lamartiniere Y; Aix Marseille Univ, Avignon Univ, CNRS, IRD, IMBE, F-13005 Marseille, France.
Slomberg D; Aix-Marseille Univ, CNRS, IRD, INRAE, Coll. De France, CEREGE, 13545 Aix-en-Provence, France.
Payet M; CEA, IRFM, 13108 Saint Paul lez Durance, France.
Tassistro V; Aix Marseille Univ, Avignon Univ, CNRS, IRD, IMBE, F-13005 Marseille, France.
Mentana A; Laboratory of Radiation Biophysics and Radiobiology, Department of Physics, University of Pavia, 27100 Pavia, Italy.
Baiocco G; Laboratory of Radiation Biophysics and Radiobiology, Department of Physics, University of Pavia, 27100 Pavia, Italy.
Rose J; Aix-Marseille Univ, CNRS, IRD, INRAE, Coll. De France, CEREGE, 13545 Aix-en-Provence, France.
Lebaron-Jacobs L; CEA, IRFM, 13108 Saint Paul lez Durance, France.
Grisolia C; CEA, IRFM, 13108 Saint Paul lez Durance, France.
Malard V; Aix Marseille Univ, CEA, CNRS, BIAM, IPM, F-13108 Saint Paul-Lez-Durance, France.
Orsière T; Aix Marseille Univ, Avignon Univ, CNRS, IRD, IMBE, F-13005 Marseille, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 08; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 08.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*
Stainless Steel*/toxicity
Comet Assay ; Humans ; Lung/metabolism ; Tritium/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis.
Autorzy:
Copp ME; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill and North Carolina State University, Raleigh, North Carolina, USA.; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, USA.
Chubinskaya S; Department of Pediatrics, Rush University Medical Center, Chicago, Illinois, USA.
Bracey DN; Department of Orthopaedics, University of North Carolina, Chapel Hill, North Carolina, USA.
Shine J; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Sessions G; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Cell Biology & Physiology, University of North Carolina, Chapel Hill, North Carolina, USA.
Loeser RF; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Cell Biology & Physiology, University of North Carolina, Chapel Hill, North Carolina, USA.; Division of Rheumatology, Allergy, and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
Diekman BO; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill and North Carolina State University, Raleigh, North Carolina, USA.; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, USA.
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Źródło:
Aging cell [Aging Cell] 2022 Sep; Vol. 21 (9), pp. e13698. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article
MeSH Terms:
Cartilage, Articular*/metabolism
Osteoarthritis*/genetics
Osteoarthritis*/metabolism
Adult ; Aged ; Aging/genetics ; Cadaver ; Cells, Cultured ; Chondrocytes/metabolism ; Comet Assay ; DNA Damage/genetics ; Humans ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 17922

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