Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Ukraiński (UK)
Przejdź do strony domowej biblioteki Uniwersytet Ekonomiczny we Wrocławiu Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""Enzyme Activation"" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-20 z 11549
Tytuł:
Nitrite Attenuates the In Vitro Inflammatory Response of Immune Cells to the SARS-CoV-2 S Protein without Interfering in the Antioxidant Enzyme Activation.
Autorzy:
Ferrer MD; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands-IUNICS, 07122 Palma, Spain.; Health Research Institute of Balearic Islands (IdISBa), 07120 Palma, Spain.
Reynés C; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands-IUNICS, 07122 Palma, Spain.
Jiménez L; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands-IUNICS, 07122 Palma, Spain.
Malagraba G; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands-IUNICS, 07122 Palma, Spain.
Monserrat-Mesquida M; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands-IUNICS, 07122 Palma, Spain.; Health Research Institute of Balearic Islands (IdISBa), 07120 Palma, Spain.; Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, 28029 Madrid, Spain.
Bouzas C; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands-IUNICS, 07122 Palma, Spain.; Health Research Institute of Balearic Islands (IdISBa), 07120 Palma, Spain.; Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, 28029 Madrid, Spain.
Sureda A; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands-IUNICS, 07122 Palma, Spain.; Health Research Institute of Balearic Islands (IdISBa), 07120 Palma, Spain.; Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, 28029 Madrid, Spain.
Tur JA; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands-IUNICS, 07122 Palma, Spain.; Health Research Institute of Balearic Islands (IdISBa), 07120 Palma, Spain.; Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, 28029 Madrid, Spain.
Pons A; Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands-IUNICS, 07122 Palma, Spain.; Health Research Institute of Balearic Islands (IdISBa), 07120 Palma, Spain.; Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, 28029 Madrid, Spain.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 05; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Metabolic Syndrome*
COVID-19*
Spike Glycoprotein, Coronavirus*
Humans ; Lipopolysaccharides/pharmacology ; Nitrites ; Antioxidants/metabolism ; Leukocytes, Mononuclear/metabolism ; Enzyme Activation ; Toll-Like Receptor 4/metabolism ; SARS-CoV-2/metabolism ; Cytokines/metabolism ; Anti-Inflammatory Agents
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Autorzy:
Lelyveld VS; Center for Computational and Integrative Biology, Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Fang Z; Center for Computational and Integrative Biology, Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Department of Chemistry, University of Chicago, Chicago, IL 60637, USA.
Szostak JW; Center for Computational and Integrative Biology, Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Department of Chemistry, University of Chicago, Chicago, IL 60637, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL 60637, USA.; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2023 Oct 27; Vol. 382 (6669), pp. 423-429. Date of Electronic Publication: 2023 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium*/chemistry
DNA*/biosynthesis
DNA-Directed DNA Polymerase*/chemistry
Coenzymes*/chemistry
Geobacillus stearothermophilus*/enzymology
Bacterial Proteins*/chemistry
Nucleotides/chemistry ; Enzyme Activation ; Crystallography, X-Ray ; Protein Conformation ; Biocatalysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation.
Autorzy:
Juyoux P; European Molecular Biology Laboratory (EMBL), Grenoble, France.
Galdadas I; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
Gobbo D; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
von Velsen J; European Molecular Biology Laboratory (EMBL), Grenoble, France.
Pelosse M; European Molecular Biology Laboratory (EMBL), Grenoble, France.
Tully M; European Synchrotron Radiation Facility, Grenoble, France.
Vadas O; Protein and peptide purification platform, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Gervasio FL; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.; Department of Chemistry, University College London, London, UK.; Institute of Structural and Molecular Biology, University College London, London, UK.; Swiss Institute of Bioinformatics, Geneva, Switzerland.
Pellegrini E; European Molecular Biology Laboratory (EMBL), Grenoble, France.
Bowler MW; European Molecular Biology Laboratory (EMBL), Grenoble, France.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2023 Sep 15; Vol. 381 (6663), pp. 1217-1225. Date of Electronic Publication: 2023 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
MAP Kinase Kinase 2*/chemistry
MAP Kinase Kinase 6*/chemistry
Mitogen-Activated Protein Kinase 14*/chemistry
Cryoelectron Microscopy ; Enzyme Activation ; Phosphorylation ; Substrate Specificity ; Protein Conformation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Unlocking the secrets to Janus kinase activation.
Autorzy:
Levine RL; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Hubbard SR; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2022 Apr 08; Vol. 376 (6589), pp. 139-140. Date of Electronic Publication: 2022 Apr 07.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Drug Development*
Enzyme Activation*
Janus Kinase 2*
Janus Kinases*
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A massive machine regulates cell death.
Autorzy:
Mace PD; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Day CL; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2023 Mar 17; Vol. 379 (6637), pp. 1093-1094. Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Inhibitor of Apoptosis Proteins*/chemistry
Inhibitor of Apoptosis Proteins*/metabolism
Caspases/metabolism ; Enzyme Activation ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Autorzy:
Hunkeler M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Jin CY; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Fischer ES; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2023 Mar 17; Vol. 379 (6637), pp. 1105-1111. Date of Electronic Publication: 2023 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Caspases*/chemistry
Caspases*/metabolism
Inhibitor of Apoptosis Proteins*/chemistry
Inhibitor of Apoptosis Proteins*/metabolism
Mitochondrial Proteins*/chemistry
Mitochondrial Proteins*/metabolism
Apoptosis Regulatory Proteins*/chemistry
Apoptosis Regulatory Proteins*/metabolism
Animals ; Humans ; Cryoelectron Microscopy ; Enzyme Activation ; High-Temperature Requirement A Serine Peptidase 2/chemistry ; High-Temperature Requirement A Serine Peptidase 2/metabolism ; Protein Domains
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Autorzy:
Strecker J; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Demircioglu FE; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Li D; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Faure G; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Wilkinson ME; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Gootenberg JS; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Abudayyeh OO; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Nishimasu H; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan.; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan.; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan.; Inamori Research Institute for Science, Kyoto 600-8411, Japan.
Macrae RK; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Zhang F; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2022 Nov 25; Vol. 378 (6622), pp. 874-881. Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
CRISPR-Cas Systems*
Endopeptidases*/chemistry
Endopeptidases*/metabolism
CRISPR-Associated Proteins*/chemistry
CRISPR-Associated Proteins*/metabolism
Proteolysis*
Deltaproteobacteria*/enzymology
Deltaproteobacteria*/genetics
RNA, Guide, CRISPR-Cas Systems*/chemistry
RNA, Guide, CRISPR-Cas Systems*/metabolism
Bacterial Proteins*/chemistry
Bacterial Proteins*/metabolism
Humans ; Cryoelectron Microscopy ; RNA, Bacterial/chemistry ; RNA, Bacterial/metabolism ; Sigma Factor/metabolism ; Transcription, Genetic ; Substrate Specificity ; Allosteric Regulation ; Enzyme Activation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cobalt Regulates Activation of Camk2α in Neurons by Influencing Fructose 1,6-bisphosphatase 2 Quaternary Structure and Subcellular Localization.
Autorzy:
Duda P; Department of Molecular Physiology and Neurobiology, University of Wrocław, 50-335 Wrocław, Poland.
Budziak B; Department of Molecular Physiology and Neurobiology, University of Wrocław, 50-335 Wrocław, Poland.
Rakus D; Department of Molecular Physiology and Neurobiology, University of Wrocław, 50-335 Wrocław, Poland.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 30; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 30.
Typ publikacji:
Journal Article
MeSH Terms:
Enzyme Activation*
Calcium-Calmodulin-Dependent Protein Kinase Type 2/*metabolism
Cobalt/*metabolism
Neurons/*metabolism
Animals ; Cells, Cultured ; Gene Silencing ; Mice, Inbred C57BL ; Neurons/cytology ; Protein Interaction Maps ; Protein Structure, Quaternary ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Regulation of the p38-MAPK pathway by hyperosmolarity and by WNK kinases.
Autorzy:
Liu Z; Cell Biology Program, The Hospital for Sick Children, PGCRL 19-9715, 686 Bay St., Toronto, ON, M5G 0A4, Canada.; Biochemistry Department, University of Toronto, Toronto, ON, Canada.
Demian W; Cell Biology Program, The Hospital for Sick Children, PGCRL 19-9715, 686 Bay St., Toronto, ON, M5G 0A4, Canada.; Biochemistry Department, University of Toronto, Toronto, ON, Canada.
Persaud A; Cell Biology Program, The Hospital for Sick Children, PGCRL 19-9715, 686 Bay St., Toronto, ON, M5G 0A4, Canada.
Jiang C; Cell Biology Program, The Hospital for Sick Children, PGCRL 19-9715, 686 Bay St., Toronto, ON, M5G 0A4, Canada.
Subramanaya AR; Department of Medicine and Cell Biology, University of Pittsburgh, Pittsburgh, USA.
Rotin D; Cell Biology Program, The Hospital for Sick Children, PGCRL 19-9715, 686 Bay St., Toronto, ON, M5G 0A4, Canada. .; Biochemistry Department, University of Toronto, Toronto, ON, Canada. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Aug 25; Vol. 12 (1), pp. 14480. Date of Electronic Publication: 2022 Aug 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MAP Kinase Signaling System*
p38 Mitogen-Activated Protein Kinases*/metabolism
Enzyme Activation ; MAP Kinase Kinase 3/metabolism ; TNF Receptor-Associated Factor 2/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Catalytic Domain Mediates Homomultimerization of MT1-MMP and the Prodomain Interferes with MT1-MMP Oligomeric Complex Assembly.
Autorzy:
Fogarasi M; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge CB2 0RE, UK.; Center of Excellence in Translational Medicine, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Dima S; Center of Excellence in Translational Medicine, Fundeni Clinical Institute, 022328 Bucharest, Romania.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2022 Aug 19; Vol. 12 (8). Date of Electronic Publication: 2022 Aug 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Matrix Metalloproteinase 14*/metabolism
Metalloendopeptidases*/metabolism
Catalytic Domain ; Enzyme Activation ; Matrix Metalloproteinases, Membrane-Associated/metabolism ; Protein Structure, Tertiary
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Role of PKC-MAPK Signalling Pathways in the Development of Hyperglycemia-Induced Cardiovascular Complications.
Autorzy:
Jubaidi FF; Center for Diagnostic, Therapeutic and Investigative Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
Zainalabidin S; Center for Toxicology and Health Risk Research, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
Taib IS; Center for Diagnostic, Therapeutic and Investigative Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
Abdul Hamid Z; Center for Diagnostic, Therapeutic and Investigative Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
Mohamad Anuar NN; Center for Toxicology and Health Risk Research, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
Jalil J; Center for Drug and Herbal Development, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
Mohd Nor NA; Center for Diagnostic, Therapeutic and Investigative Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.; Faculty of Health Sciences, University College MAIWP International, Kuala Lumpur 68100, Malaysia.
Budin SB; Center for Diagnostic, Therapeutic and Investigative Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 02; Vol. 23 (15). Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Diabetes Complications*/complications
Diabetes Mellitus*
Hyperglycemia*/complications
Enzyme Activation ; Humans ; MAP Kinase Signaling System ; Mitogen-Activated Protein Kinases/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Functional mechanism of AMPK activation in mitochondrial regeneration of rat peritoneal macrophages mediated by uremic serum.
Autorzy:
Chen; Department of Critical Care Medcine, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu, China.
Zuo K; Department of Critical Care Medcine, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu, China.
Liang X; Department of Critical Care Medcine, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu, China.
Wang M; Department of Critical Care Medcine, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu, China.
Zhang H; Department of Critical Care Medcine, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu, China.
Zhou R; Department of Critical Care Medcine, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu, China.
Liu X; Department of Critical Care Medcine, Gansu Provincial Maternity and Child-care Hospital, Lanzhou, Gansu, China.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2020 Sep 28; Vol. 15 (9), pp. e0235960. Date of Electronic Publication: 2020 Sep 28 (Print Publication: 2020).
Typ publikacji:
Journal Article
MeSH Terms:
Enzyme Activation*
AMP-Activated Protein Kinases/*metabolism
Macrophages, Peritoneal/*metabolism
Mitochondria/*metabolism
Uremia/*metabolism
Animals ; Macrophages, Peritoneal/pathology ; Male ; Mitochondria/pathology ; Mitochondrial Dynamics ; RNA, Messenger/metabolism ; RNA, Mitochondrial/metabolism ; Rats ; Rats, Sprague-Dawley ; Uremia/blood ; Uremia/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.
Autorzy:
Michel M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Benítez-Buelga C; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.; Instituto de Investigaciones Biomédicas Alberto Sols (CSIC/UAM), 28029 Madrid, Spain.
Calvo PA; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049 Madrid, Spain.
Hanna BMF; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Mortusewicz O; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Masuyer G; Department of Pharmacy and Pharmacology, Centre for Therapeutic Innovation, University of Bath, Bath BA2 7AY, UK.; Department of Biochemistry and Biophysics, Stockholm University, 106 91 Stockholm, Sweden.
Davies J; Department of Biochemistry and Biophysics, Stockholm University, 106 91 Stockholm, Sweden.
Wallner O; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Sanjiv K; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Albers JJ; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Castañeda-Zegarra S; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Jemth AS; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Visnes T; Department of Biotechnology and Nanomedicine, SINTEF Industry, N-7465 Trondheim, Norway.
Sastre-Perona A; Experimental Therapies and Novel Biomarkers in Cancer, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.
Danda AN; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Homan EJ; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Marimuthu K; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Zhenjun Z; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Chi CN; Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Sarno A; Department of Environment and New Resources, SINTEF Ocean, N-7496 Trondheim, Norway.
Wiita E; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
von Nicolai C; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Komor AJ; Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Department of Biomolecular Chemistry, 07745 Jena, Germany.
Rajagopal V; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Müller S; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Hank EC; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Varga M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Scaletti ER; Department of Biochemistry and Biophysics, Stockholm University, 106 91 Stockholm, Sweden.; Department of Experimental Medical Science, Lund University, Lund, Sweden.
Pandey M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.; Sheffield Cancer Centre, Department of Oncology and Metabolism, University of Sheffield, Sheffield S10 2RX, UK.
Karsten S; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Haslene-Hox H; Department of Biotechnology and Nanomedicine, SINTEF Industry, N-7465 Trondheim, Norway.
Loevenich S; Department of Biotechnology and Nanomedicine, SINTEF Industry, N-7465 Trondheim, Norway.
Marttila P; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Rasti A; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Mamonov K; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Ortis F; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Schömberg F; Institute of Organic and Macromolecular Chemistry, Friedrich Schiller University Jena, 07743 Jena, Germany.
Loseva O; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Stewart J; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
D'Arcy-Evans N; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Koolmeister T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Henriksson M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Michel D; Chemical Processes and Pharmaceutical Development, Unit Process Chemistry I, Research Institutes of Sweden - RISE, 151 36 Södertälje, Sweden.
de Ory A; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 106 91 Stockholm, Sweden.
Acero L; Experimental Therapies and Novel Biomarkers in Cancer, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.
Calvete O; Familial Cancer Clinical Unit, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.
Scobie M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Hertweck C; Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute, Department of Biomolecular Chemistry, 07745 Jena, Germany.; Institute of Microbiology, Friedrich-Schiller-University Jena, 07743 Jena, Germany.
Vilotijevic I; Institute of Organic and Macromolecular Chemistry, Friedrich Schiller University Jena, 07743 Jena, Germany.
Kalderén C; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
Osorio A; Familial Cancer Clinical Unit, Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Perona R; Instituto de Investigaciones Biomédicas Alberto Sols (CSIC/UAM), 28029 Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Stolz A; Institute of Biochemistry II and Buchmann Institute for Molecular Life Science, Goethe University Frankfurt, 60590 Frankfurt, Germany.
Stenmark P; Department of Biochemistry and Biophysics, Stockholm University, 106 91 Stockholm, Sweden.; Department of Experimental Medical Science, Lund University, Lund, Sweden.
Berglund UW; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.
de Vega M; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049 Madrid, Spain.
Helleday T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden.; Sheffield Cancer Centre, Department of Oncology and Metabolism, University of Sheffield, Sheffield S10 2RX, UK.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2022 Jun 24; Vol. 376 (6600), pp. 1471-1476. Date of Electronic Publication: 2022 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Damage*/drug effects
DNA Glycosylases*/chemistry
DNA Glycosylases*/drug effects
DNA Repair*/drug effects
Oxidative Stress*/genetics
Biocatalysis/drug effects ; Enzyme Activation ; Glycine/chemistry ; Humans ; Ligands ; Phenylalanine/chemistry ; Substrate Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Activation of Focal Adhesion Kinase Restores Simulated Microgravity-Induced Inhibition of Osteoblast Differentiation via Wnt/Β-Catenin Pathway.
Autorzy:
Fan C; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, SK S7N 4H4, Canada.; Department of Oncology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.; School of Life Sciences, Beijing Institute of Technology, Beijing 100811, China.
Wu Z; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, SK S7N 4H4, Canada.; Department of Oncology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Cooper DML; Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Magnus A; Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Harrison K; Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Eames BF; Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Chibbar R; Department of Pathology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Groot G; Department of Surgery, Royal University Hospital, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Huang J; Department of Blood Transfusion, Affiliated Hospital of Zunyi Medical University, Zunyi 563006, China.
Genth H; Institute of Toxicology, Hannover Medical School, D-30625 Hannover, Germany.
Zhang J; School of Life Sciences, Beijing Institute of Technology, Beijing 100811, China.
Tan X; School of Life Sciences, Beijing Institute of Technology, Beijing 100811, China.
Deng Y; School of Life Sciences, Beijing Institute of Technology, Beijing 100811, China.
Xiang J; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, SK S7N 4H4, Canada.; Department of Oncology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 17; Vol. 23 (10). Date of Electronic Publication: 2022 May 17.
Typ publikacji:
Journal Article
MeSH Terms:
Focal Adhesion Protein-Tyrosine Kinases*/metabolism
Osteoblasts*/cytology
Osteoblasts*/metabolism
Weightlessness*
Wnt Signaling Pathway*
beta Catenin*/metabolism
3T3 Cells ; Animals ; Enzyme Activation ; Focal Adhesion Kinase 1/metabolism ; Mice ; X-Ray Microtomography
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Sirtuin-1 expression and activity is diminished in aged liver grafts.
Autorzy:
Scheuermann U; Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Leipzig, Germany.
Seyferth ER; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Abraham N; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Kesseli SJ; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Halpern SE; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Zhu M; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Song M; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Hartwig MG; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Parker W; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Kwun J; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Cherry AD; Department of Anesthesiology, Duke University, Durham, USA.
Lee J; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA.
Barbas AS; Department of Surgery, Duke University, DUMC 3512, Durham, NC, 27710, USA. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2020 Jul 17; Vol. 10 (1), pp. 11860. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Enzyme Activation*
Gene Expression*
Liver Transplantation*
Organ Preservation*
Liver/*metabolism
Sirtuin 1/*genetics
Sirtuin 1/*metabolism
Animals ; Antioxidants/metabolism ; Biomarkers ; Cryopreservation ; Cytokines/metabolism ; Graft Survival ; Inflammation Mediators/metabolism ; Liver Function Tests ; Male ; Mitochondria/metabolism ; Models, Animal ; Oxygen Consumption ; Rats ; Reperfusion Injury ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bioinformatics Analysis of Global Proteomic and Phosphoproteomic Data Sets Revealed Activation of NEK2 and AURKA in Cancers.
Autorzy:
Deb B; Institute of Bioinformatics, International Technology Park, Bangalore 560066, India.; Manipal Academy of Higher Education (MAHE), Manipal 576104, India.
Sengupta P; Department of Biotechnology, National Institute of Technology Durgapur, Mahatma Gandhi Avenue, Durgapur, West Bengal 713209, India.
Sambath J; Institute of Bioinformatics, International Technology Park, Bangalore 560066, India.
Kumar P; Institute of Bioinformatics, International Technology Park, Bangalore 560066, India.; Manipal Academy of Higher Education (MAHE), Manipal 576104, India.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2020 Feb 04; Vol. 10 (2). Date of Electronic Publication: 2020 Feb 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Enzyme Activation*
Aurora Kinase A/*metabolism
NIMA-Related Kinases/*metabolism
Neoplasms/*metabolism
Phosphoproteins/*metabolism
Cell Cycle ; Humans ; Neoplasms/enzymology ; Protein Interaction Maps ; Proteomics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Current Strategies for Real-Time Enzyme Activation.
Autorzy:
Wang F; Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Science, Jilin University, Changchun 130021, China.
Liu Y; Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Science, Jilin University, Changchun 130021, China.
Du C; Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Science, Jilin University, Changchun 130021, China.
Gao R; Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Science, Jilin University, Changchun 130021, China.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2022 Apr 19; Vol. 12 (5). Date of Electronic Publication: 2022 Apr 19.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Nanostructures*/chemistry
Enzyme Activation ; Kinetics ; Magnetic Fields ; Ultrasonic Waves
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation.
Autorzy:
Glassman CR; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Tsutsumi N; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Saxton RA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Lupardus PJ; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Jude KM; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Garcia KC; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2022 Apr 08; Vol. 376 (6589), pp. 163-169. Date of Electronic Publication: 2022 Mar 10.
Typ publikacji:
Journal Article
MeSH Terms:
Janus Kinase 1*/chemistry
Janus Kinase 1*/metabolism
Receptors, Cytokine*/chemistry
src Homology Domains*
Allosteric Regulation ; Cryoelectron Microscopy ; Enzyme Activation ; Humans ; Mutation ; Myeloproliferative Disorders/enzymology ; Myeloproliferative Disorders/genetics ; Phosphorylation ; Protein Multimerization ; STAT Transcription Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prolonged treatment with the proteasome inhibitor MG-132 induces apoptosis in PC12 rat pheochromocytoma cells.
Autorzy:
Tarjányi O; Department of Medical Biology and Central Electron Microscope Laboratory, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary.; Signal Transduction Research Group, János Szentágothai Research Centre, Ifjúság útja 20., Pecs, 7624, Hungary.
Haerer J; Department of Medical Biology and Central Electron Microscope Laboratory, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary.
Vecsernyés M; Department of Medical Biology and Central Electron Microscope Laboratory, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary.; Signal Transduction Research Group, János Szentágothai Research Centre, Ifjúság útja 20., Pecs, 7624, Hungary.
Berta G; Department of Medical Biology and Central Electron Microscope Laboratory, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary.; Signal Transduction Research Group, János Szentágothai Research Centre, Ifjúság útja 20., Pecs, 7624, Hungary.
Stayer-Harci A; Department of Medical Biology and Central Electron Microscope Laboratory, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary.; Signal Transduction Research Group, János Szentágothai Research Centre, Ifjúság útja 20., Pecs, 7624, Hungary.
Balogh B; Department of Medical Biology and Central Electron Microscope Laboratory, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary.
Farkas K; Institute of Bioanalysis, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary.
Boldizsár F; Department of Immunology and Biotechnology, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary.
Szeberényi J; Department of Medical Biology and Central Electron Microscope Laboratory, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary.; Signal Transduction Research Group, János Szentágothai Research Centre, Ifjúság útja 20., Pecs, 7624, Hungary.
Sétáló G Jr; Department of Medical Biology and Central Electron Microscope Laboratory, University of Pécs, Medical School, Szigeti út 12., Pecs, 7624, Hungary. .; Signal Transduction Research Group, János Szentágothai Research Centre, Ifjúság útja 20., Pecs, 7624, Hungary. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Apr 06; Vol. 12 (1), pp. 5808. Date of Electronic Publication: 2022 Apr 06.
Typ publikacji:
Journal Article
MeSH Terms:
Leupeptins*
Proteasome Inhibitors*/pharmacology
Adrenal Gland Neoplasms ; Animals ; Apoptosis/physiology ; Caspase 3 ; Enzyme Activation ; JNK Mitogen-Activated Protein Kinases ; PC12 Cells ; Pheochromocytoma ; Proto-Oncogene Proteins c-akt ; Rats ; p38 Mitogen-Activated Protein Kinases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The analgesic effects of β-elemene in rats with neuropathic pain by inhibition of spinal astrocytic ERK activation.
Autorzy:
Ma LT; Department of Traditional Chinese Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.; Department of Gastroenterology, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Bai Y; Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, China.
Cao P; Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, China.
Ren KX; Department of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Chen J; Department of Anatomy, Histology and Embryology, Preclinical School of Medicine, Air Force Medical University, Xi'an, China.
Zhang T; Department of Anatomy, Histology and Embryology, Preclinical School of Medicine, Air Force Medical University, Xi'an, China.
Fan BY; Department of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an Jiaotong University, Xi'an, China.
Qiao Y; Laser Medical Center, Hainan Hospital, PLA General Hospital, Sanya, China.
Yan HY; 36674The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Wang JJ; Department of Gastroenterology, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Li YQ; Department of Anatomy, Histology and Embryology, Preclinical School of Medicine, Air Force Medical University, Xi'an, China.; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.; Department of Anatomy, College of Basic Medicine, Dali University, Dali, China.
Zheng J; Department of Traditional Chinese Medicine, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Pokaż więcej
Źródło:
Molecular pain [Mol Pain] 2022 Apr; Vol. 18, pp. 17448069221121562.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hyperalgesia*/complications
Hyperalgesia*/drug therapy
Hyperalgesia*/metabolism
Neuralgia*/drug therapy
Neuralgia*/metabolism
Analgesics/metabolism ; Analgesics/pharmacology ; Analgesics/therapeutic use ; Animals ; Enzyme Activation ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Rats ; Rats, Sprague-Dawley ; Sesquiterpenes ; Spinal Cord/metabolism ; Spinal Cord Dorsal Horn/metabolism ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 11549

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies