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Wyszukujesz frazę ""Evans, Richard J."" wg kryterium: Autor


Wyświetlanie 1-6 z 6
Tytuł:
Mechanistic insights from resolving ligand-dependent kinetics of conformational changes at ATP-gated P2X1R ion channels.
Autorzy:
Fryatt AG; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE1 7RH, United Kingdom.
Dayl S; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE1 7RH, United Kingdom.; Department of Chemistry, College of Science, University of Baghdad, Baghdad, Iraq.
Cullis PM; Department of Chemistry, University of Leicester, Leicester, LE1 7RH, United Kingdom.
Schmid R; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE1 7RH, United Kingdom.; Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, LE1 7RH, United Kingdom.
Evans RJ; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE1 7RH, United Kingdom.
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Źródło:
Scientific reports [Sci Rep] 2016 Sep 12; Vol. 6, pp. 32918. Date of Electronic Publication: 2016 Sep 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenosine Triphosphate/*agonists
Adenosine Triphosphate/*pharmacology
Receptors, Purinergic P2X1/*chemistry
Receptors, Purinergic P2X1/*metabolism
Xenopus laevis/*genetics
Adenosine Triphosphate/chemistry ; Animals ; Binding Sites ; Dinucleoside Phosphates/pharmacology ; Humans ; Kinetics ; Ligands ; Models, Molecular ; Molecular Dynamics Simulation ; Mutation ; Patch-Clamp Techniques ; Protein Binding ; Protein Conformation ; Receptors, Purinergic P2X1/genetics
Czasopismo naukowe
Tytuł:
Structural interpretation of P2X receptor mutagenesis studies on drug action.
Autorzy:
Evans RJ; Cell Physiology & Pharmacology, University of Leicester, Leicester, UK.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2010 Nov; Vol. 161 (5), pp. 961-71.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Models, Molecular*
Mutagenesis*
Receptors, Purinergic P2X/*metabolism
Adenosine Triphosphate/metabolism ; Allosteric Regulation ; Animals ; Binding Sites ; Humans ; Ligands ; Protein Binding ; Protein Conformation ; Receptors, Purinergic P2X/chemistry ; Receptors, Purinergic P2X4/chemistry ; Receptors, Purinergic P2X4/metabolism
Czasopismo naukowe
Tytuł:
Evidence for P2Y1, P2Y2, P2Y6 and atypical UTP-sensitive receptors coupled to rises in intracellular calcium in mouse cultured superior cervical ganglion neurons and glia.
Autorzy:
Calvert JA; Department of Cell Physiology & Pharmacology, University of Leicester, Medical Sciences Building, University Road, Leicester LE1 9HN.
Atterbury-Thomas AE
Leon C
Forsythe ID
Gachet C
Evans RJ
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2004 Nov; Vol. 143 (5), pp. 525-32. Date of Electronic Publication: 2004 Oct 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium/*metabolism
Neuroglia/*metabolism
Neurons/*metabolism
Pyridoxal Phosphate/*analogs & derivatives
Receptors, Purinergic P2/*physiology
Superior Cervical Ganglion/*metabolism
Uridine Triphosphate/*pharmacology
Animals ; Cells, Cultured ; Female ; Fluorescent Dyes ; Male ; Mice ; Mice, Inbred C57BL ; Neuroglia/drug effects ; Neurons/drug effects ; Pyridoxal Phosphate/pharmacology ; Receptors, Purinergic P2/drug effects ; Receptors, Purinergic P2/genetics ; Receptors, Purinergic P2Y1 ; Receptors, Purinergic P2Y2 ; Reverse Transcriptase Polymerase Chain Reaction ; Superior Cervical Ganglion/cytology ; Superior Cervical Ganglion/drug effects ; Suramin/pharmacology ; Uridine Diphosphate/pharmacology
Czasopismo naukowe
Tytuł:
Emerging roles for P2X1 receptors in platelet activation.
Autorzy:
Mahaut-Smith MP; Department of Physiology, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK. />Tolhurst G
Evans RJ
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Źródło:
Platelets [Platelets] 2004 May; Vol. 15 (3), pp. 131-44.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Platelet Activation*
Receptors, Purinergic P2/*physiology
Animals ; Blood Platelets/metabolism ; Blood Platelets/physiology ; Humans ; Ion Channels/metabolism ; Ion Channels/physiology ; Megakaryocytes/metabolism ; Megakaryocytes/physiology ; Receptors, Purinergic P2X ; Signal Transduction ; Thrombosis/etiology
Czasopismo naukowe
Tytuł:
A study of P2X1 receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors.
Autorzy:
Vial C; Department of Cell Physiology & Pharmacology, Medical Sciences Building, University of Leicester, University Road, Leicester, LE1 9HN.
Rolf MG
Mahaut-Smith MP
Evans RJ
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2002 Jan; Vol. 135 (2), pp. 363-72.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets/*metabolism
Megakaryocytes/*metabolism
Receptors, Purinergic P2/*biosynthesis
Adenosine Triphosphate/pharmacology ; Adenosine Triphosphate/physiology ; Animals ; Blood Platelets/drug effects ; Calcium/metabolism ; Humans ; Megakaryocytes/drug effects ; Mice ; Mice, Mutant Strains ; Purinergic P2 Receptor Agonists ; Receptors, Purinergic P2/deficiency ; Receptors, Purinergic P2/genetics ; Receptors, Purinergic P2X
Czasopismo naukowe
    Wyświetlanie 1-6 z 6

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