- Tytuł:
- Mechanistic insights from resolving ligand-dependent kinetics of conformational changes at ATP-gated P2X1R ion channels.
- Autorzy:
- Źródło:
- Scientific reports [Sci Rep] 2016 Sep 12; Vol. 6, pp. 32918. Date of Electronic Publication: 2016 Sep 12.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Adenosine Triphosphate/*agonists
Adenosine Triphosphate/*pharmacology
Receptors, Purinergic P2X1/*chemistry
Receptors, Purinergic P2X1/*metabolism
Xenopus laevis/*genetics
Adenosine Triphosphate/chemistry ; Animals ; Binding Sites ; Dinucleoside Phosphates/pharmacology ; Humans ; Kinetics ; Ligands ; Models, Molecular ; Molecular Dynamics Simulation ; Mutation ; Patch-Clamp Techniques ; Protein Binding ; Protein Conformation ; Receptors, Purinergic P2X1/genetics
Czasopismo naukowe