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Tytuł:
Apoptosis dysfunction: unravelling the interplay between ZBP1 activation and viral invasion in innate immune responses.
Autorzy:
Zhan J; Department of Neurosurgery, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China.; HuanKui Academy, Nanchang University, Nanchang, Jiangxi Province, 330006, China.
Wang J; Department of Neurosurgery, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China.
Liang Y; School of Basic Medical Sciences, Nanchang University, Nanchang, Jiangxi Province, 330006, China.
Wang L; HuanKui Academy, Nanchang University, Nanchang, Jiangxi Province, 330006, China.
Huang L; HuanKui Academy, Nanchang University, Nanchang, Jiangxi Province, 330006, China.
Liu S; School of Basic Medical Sciences, Nanchang University, Nanchang, Jiangxi Province, 330006, China.
Zeng X; School of Basic Medical Sciences, Nanchang University, Nanchang, Jiangxi Province, 330006, China.; Medical College, Jinhua Polytechnic, Jinhua, Zhejiang Province, 321017, China.
Zeng E; Department of Neurosurgery, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China. .
Wang H; Department of Neurosurgery, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, China. .; School of Basic Medical Sciences, Nanchang University, Nanchang, Jiangxi Province, 330006, China. .; Medical College, Jinhua Polytechnic, Jinhua, Zhejiang Province, 321017, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 24; Vol. 22 (1), pp. 149. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Immunity, Innate*
Humans ; Pyroptosis ; Inflammation ; Cytoplasm
Czasopismo naukowe
Tytuł:
Elaiophylin Elicits Robust Anti-Tumor Responses via Apoptosis Induction and Attenuation of Proliferation, Migration, Invasion, and Angiogenesis in Pancreatic Cancer Cells.
Autorzy:
Huang L; Department of Pharmacy, Jining Medical University, Rizhao 276500, China.
Liu Y; Department of Pharmacy, Jining Medical University, Rizhao 276500, China.
Pan Y; Sichuan Key Medical Laboratory of New Drug Discovery and Drugability Evaluation, Key Laboratory of Medical Electrophysiology of Ministry of Education, School of Pharmacy, Southwest Medical University, Luzhou 646000, China.
Liu C; Department of Pharmacy, Jining Medical University, Rizhao 276500, China.
Gao H; Department of Pharmacy, Jining Medical University, Rizhao 276500, China.
Ren Q; Department of Pharmacy, Jining Medical University, Rizhao 276500, China.
Wang J; Department of Pharmacy, Jining Medical University, Rizhao 276500, China.
Wang H; Department of Pharmacy, Jining Medical University, Rizhao 276500, China.
Zhang Y; Department of Pharmacy, Jining Medical University, Rizhao 276500, China.
Wu A; Sichuan Key Medical Laboratory of New Drug Discovery and Drugability Evaluation, Key Laboratory of Medical Electrophysiology of Ministry of Education, School of Pharmacy, Southwest Medical University, Luzhou 646000, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Oct 21; Vol. 28 (20). Date of Electronic Publication: 2023 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Pancreatic Neoplasms*/metabolism
Humans ; Cell Line, Tumor ; Wnt Signaling Pathway ; Cell Proliferation ; Cell Movement ; beta Catenin/metabolism ; Gene Expression Regulation, Neoplastic ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
PANoptosis: Mechanism and Role in Pulmonary Diseases.
Autorzy:
Chen S; Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Jiang J; Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Li T; Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Huang L; Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 19; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Apoptosis*
Acute Lung Injury*
Humans ; Cell Death ; Homeostasis ; Inflammation ; Pyroptosis
Czasopismo naukowe
Tytuł:
Bcl-3 regulates T cell function through energy metabolism.
Autorzy:
Liu H; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Zeng L; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Pan M; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Huang L; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Li H; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Liu M; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Niu X; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Zhang C; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China.
Wang H; Henan Key Laboratory of Immunology and Targeted Drug, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Laboratory Medicine, Xinxiang Medical University, Xinxiang, China. .
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Źródło:
BMC immunology [BMC Immunol] 2023 Oct 04; Vol. 24 (1), pp. 35. Date of Electronic Publication: 2023 Oct 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
NF-kappa B*/metabolism
B-Cell Lymphoma 3 Protein*/metabolism
T-Lymphocytes*/metabolism
Humans ; Cell Survival ; Energy Metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
Peroxisome-Mediated Reactive Oxygen Species Signals Modulate Programmed Cell Death in Plants.
Autorzy:
Huang L; State Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.
Liu Y; State Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.
Wang X; State Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.
Jiang C; State Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.
Zhao Y; State Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.
Lu M; State Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.
Zhang J; State Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou 311300, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 03; Vol. 23 (17). Date of Electronic Publication: 2022 Sep 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Apoptosis*/physiology
Peroxisomes*/metabolism
Metabolic Networks and Pathways ; Plants/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of MAGL activates the Keap1/Nrf2 pathway to attenuate glucocorticoid-induced osteonecrosis of the femoral head.
Autorzy:
Yang N; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Sun H; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Xue Y; Department of Orthopaedics, Changshu Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, Changshu, China.
Zhang W; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Wang H; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Tao H; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Liang X; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Li M; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Xu Y; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Chen L; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Zhang L; Department of Orthopaedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Huang L; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
Geng D; Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2021 Jun; Vol. 11 (6), pp. e447.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Femur Head/*drug effects
Glucocorticoids/*toxicity
Kelch-Like ECH-Associated Protein 1/*metabolism
Monoacylglycerol Lipases/*antagonists & inhibitors
NF-E2-Related Factor 2/*metabolism
Osteonecrosis/*prevention & control
Animals ; Cell Differentiation ; Femur Head/pathology ; Kelch-Like ECH-Associated Protein 1/genetics ; Male ; Mesenchymal Stem Cells/drug effects ; Mesenchymal Stem Cells/metabolism ; Mesenchymal Stem Cells/pathology ; NF-E2-Related Factor 2/genetics ; Osteoblasts/drug effects ; Osteoblasts/metabolism ; Osteoblasts/pathology ; Osteonecrosis/chemically induced ; Osteonecrosis/metabolism ; Osteonecrosis/pathology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
MicroRNA expression profiling after recurrent febrile seizures in rat and emerging role of miR-148a-3p/SYNJ1 axis.
Autorzy:
Xu J; Department of Neurology, Maternal and Child Health Hospital of Weifang Medical University, Weifang, 261011, China.; Department of Clinical Lab, Maternal and Child Health Hospital of Weifang Medical University, Weifang, 261011, China.
Sun M; Department of Clinical Lab, Maternal and Child Health Hospital of Weifang Medical University, Weifang, 261011, China.
Li X; Department of Pediatric, Maternal and Child Health Hospital of Weifang Medical University, Weifang, 261011, China.
Huang L; Department of Cancer Blood Disease, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
Gao Z; Department of Pediatric, Maternal and Child Health Hospital of Weifang Medical University, Weifang, 261011, China. .
Gao J; Department of Pediatric, Maternal and Child Health Hospital of Weifang Medical University, Weifang, 261011, China. .
Xie A; Department of Neurology, Maternal and Child Health Hospital of Weifang Medical University, Weifang, 261011, China. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jan 13; Vol. 11 (1), pp. 1262. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Signal Transduction*
MicroRNAs/*biosynthesis
Seizures, Febrile/*metabolism
Animals ; Gene Expression Profiling ; Oligonucleotide Array Sequence Analysis ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphoric Monoester Hydrolases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley ; Seizures, Febrile/pathology
Czasopismo naukowe
Tytuł:
MicroRNA-378-3p/5p represses proliferation and induces apoptosis of oral squamous carcinoma cells via targeting KLK4.
Autorzy:
Cui Z; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, China.
Bao X; Department of Orthodontics, School and Hospital of Stomatology, Jilin University, Changchun, China.
Liu Q; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, China.
Li Q; VIP Integrated Department, School and Hospital of Stomatology, Jilin University, Changchun, China.
Huang L; Department of Orthodontics, School and Hospital of Stomatology, Jilin University, Changchun, China.
Wang H; Department of Dental Implantology, School and Hospital of Stomatology, Jilin University, Changchun, China.
Jiao K; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, China.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2020 Apr; Vol. 47 (4), pp. 713-724. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*genetics
Kallikreins/*genetics
MicroRNAs/*genetics
Squamous Cell Carcinoma of Head and Neck/*pathology
Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Knockdown Techniques ; Humans ; MicroRNAs/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Signal Transduction/genetics ; Squamous Cell Carcinoma of Head and Neck/genetics ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
"French fries"-like luminescent metal organic frameworks for the fluorescence determination of cytochrome c released by apoptotic cells and screening of anticancer drug activity.
Autorzy:
Xie R; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Liu Y; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Yang P; School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510641, Guangdong, China.
Huang L; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zou X; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Liu J; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Ren Q; School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510641, Guangdong, China.
Tao J; School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510641, Guangdong, China. .
Zhao P; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, Guangdong, China. .
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Źródło:
Mikrochimica acta [Mikrochim Acta] 2020 Mar 12; Vol. 187 (4), pp. 221. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/drug effects
Fluorescence*
Antineoplastic Agents/*chemistry
Cytochromes c/*analysis
Luminescent Agents/*chemistry
Metal-Organic Frameworks/*chemistry
Antineoplastic Agents/pharmacology ; Cytochromes c/metabolism ; Drug Evaluation, Preclinical ; HeLa Cells ; Humans ; Molecular Structure ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
Small nucleolar RNA Sf-15 regulates proliferation and apoptosis of Spodoptera frugiperda Sf9 cells.
Autorzy:
Wu B; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Huang L; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Qiu W; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Liu X; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Shen Y; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Lu Y; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Yang Z; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Li X; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Cui B; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Xu S; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Qiao H; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Qiu R; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Yao L; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China.
Kan Y; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China. .
Li D; China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, Nanyang Normal University, 1638 Wolong Road, Nanyang, 473061, Henan, China. .
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Źródło:
BMC molecular biology [BMC Mol Biol] 2019 Apr 11; Vol. 20 (1), pp. 12. Date of Electronic Publication: 2019 Apr 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*genetics
Cell Proliferation/*genetics
RNA, Small Nucleolar/*genetics
Spodoptera/*genetics
Animals ; Gene Expression Profiling ; Sf9 Cells
Czasopismo naukowe
Tytuł:
PARP inhibitor re‑sensitizes Adriamycin resistant leukemia cells through DNA damage and apoptosis.
Autorzy:
Wu J; Department of Hematology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Xiao S; Department of Hematology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Yuan M; Department of Hematology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Li Q; Department of Hematology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Xiao G; Department of Hematology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Wu W; Department of Hematology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Ouyang Y; Center for Medical Experiments, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Huang L; Center for Medical Experiments, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
Yao C; Department of Hematology, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2019 Jan; Vol. 19 (1), pp. 75-84. Date of Electronic Publication: 2018 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
DNA Damage/*drug effects
Doxorubicin/*pharmacology
Drug Resistance, Neoplasm/*drug effects
Poly (ADP-Ribose) Polymerase-1/*antagonists & inhibitors
Poly(ADP-ribose) Polymerase Inhibitors/*pharmacology
Adult ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Female ; G2 Phase Cell Cycle Checkpoints/drug effects ; Humans ; K562 Cells ; Leukemia/drug therapy ; Leukemia/metabolism ; Male ; Middle Aged ; Phthalazines/pharmacology ; Piperazines/pharmacology ; Young Adult
Czasopismo naukowe
Tytuł:
Anticancer effects of FL34 through the inhibition of GLI1 in glioblastoma.
Autorzy:
Li Y; Department of Pharmacology, Institute of Material Medical, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Tang K; Department of Pharmacology, Institute of Material Medical, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Huang L; Department of Pharmacology, Institute of Material Medical, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liu C; Department of Pharmacology, Institute of Material Medical, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Du Q; Department of Pharmacology, Institute of Material Medical, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li T; Department of Pharmacology, Institute of Material Medical, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yan C; Department of Pharmacology, Institute of Material Medical, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Feng Z; Department of Synthetic Medicinal Chemistry, Beijing Key Laboratory of Active Substance Discovery and Drug ability Evaluation, Institute of Material Medical, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li X; Department of Neurosurgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2019; Vol. 15 (4), pp. 889-898.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Cell Movement/*drug effects
Cell Proliferation/*drug effects
Glioblastoma/*drug therapy
Small Molecule Libraries/*pharmacology
Zinc Finger Protein GLI1/*antagonists & inhibitors
Animals ; Female ; Glioblastoma/metabolism ; Glioblastoma/pathology ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays ; Zinc Finger Protein GLI1/genetics ; Zinc Finger Protein GLI1/metabolism
Czasopismo naukowe
Tytuł:
MiR-486 promotes proliferation and suppresses apoptosis in myeloid cells by targeting Cebpa in vitro.
Autorzy:
Jiang J; Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Huashan Hospital, Fudan University, Shanghai, China.
Gao Q; Department of Oncology, Huashan Hospital, Fudan University, Shanghai, China.
Gong Y; Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Huang L; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou, China.
Lin H; Department of Oncology, Huashan Hospital North, Fudan University, Shanghai, China.
Zhou X; Department of Oncology, Huashan Hospital, Fudan University, Shanghai, China.
Liang X; Department of Oncology, Huashan Hospital, Fudan University, Shanghai, China.
Guo W; Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
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Źródło:
Cancer medicine [Cancer Med] 2018 Sep; Vol. 7 (9), pp. 4627-4638. Date of Electronic Publication: 2018 Aug 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation*
RNA Interference*
Apoptosis/*genetics
CCAAT-Enhancer-Binding Proteins/*genetics
MicroRNAs/*genetics
Myeloid Cells/*metabolism
3' Untranslated Regions ; Animals ; Cell Differentiation/genetics ; Cell Line, Tumor ; Cell Proliferation ; Computational Biology/methods ; Female ; Gene Expression Profiling ; Humans ; Melanoma, Experimental ; Mice ; Myeloid Cells/cytology ; Myeloid-Derived Suppressor Cells/cytology ; Myeloid-Derived Suppressor Cells/metabolism
Czasopismo naukowe
Tytuł:
Design, Synthesis and Anticancer Evaluation of Fangchinoline Derivatives.
Autorzy:
Liu Y; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Baijin Road, Guiyang 550014, China. .
Xia B; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Baijin Road, Guiyang 550014, China. .
Lan J; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Baijin Road, Guiyang 550014, China. .
Hu S; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Baijin Road, Guiyang 550014, China. .
Huang L; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Baijin Road, Guiyang 550014, China. .
Chen C; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Baijin Road, Guiyang 550014, China. .
Zeng X; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Baijin Road, Guiyang 550014, China. .
Lou H; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Baijin Road, Guiyang 550014, China. .
Lin C; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .
Pan W; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang 550014, China. .; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Baijin Road, Guiyang 550014, China. .
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2017 Nov 08; Vol. 22 (11). Date of Electronic Publication: 2017 Nov 08.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/chemical synthesis
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Benzylisoquinolines*/chemical synthesis
Benzylisoquinolines*/chemistry
Benzylisoquinolines*/pharmacology
Apoptosis/*drug effects
Melanoma/*drug therapy
Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Humans ; K562 Cells ; Melanoma/metabolism ; Melanoma/pathology
Czasopismo naukowe
Tytuł:
CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy.
Autorzy:
Lei Y; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
Wang S; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
Ren B; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
Wang J; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
Chen J; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
Lu J; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
Zhan S; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
Fu Y; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
Huang L; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
Tan J; Department of Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.
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Źródło:
PloS one [PLoS One] 2017 Aug 25; Vol. 12 (8), pp. e0183680. Date of Electronic Publication: 2017 Aug 25 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*physiology
Autophagy/*physiology
Carcinoma, Hepatocellular/*pathology
Endoplasmic Reticulum Stress/*physiology
Liver Neoplasms/*pathology
Transcription Factor CHOP/*physiology
Animals ; Carcinoma, Hepatocellular/metabolism ; Cell Line, Tumor ; Endoplasmic Reticulum Chaperone BiP ; Liver Neoplasms/metabolism ; Mice ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe
Tytuł:
Naringenin prevents ischaemic stroke damage via anti-apoptotic and anti-oxidant effects.
Autorzy:
Wang K; Southern Medical University, Guangzhou, China.; Department of Neurology, RuiKang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.
Chen Z; Guangxi University of Chinese Medicine, Nanning, China.
Huang J; Department of Neurology, RuiKang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.
Huang L; Department of Neurology, RuiKang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.
Luo N; Department of Neurology, RuiKang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.
Liang X; Department of Neurology, RuiKang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.
Liang M; Department of Neurology, RuiKang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.
Xie W; Southern Medical University, Guangzhou, China.; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.; Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2017 Aug; Vol. 44 (8), pp. 862-871.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants/*pharmacology
Apoptosis/*drug effects
Flavanones/*pharmacology
Infarction, Middle Cerebral Artery/*complications
Stroke/*complications
Stroke/*pathology
Active Transport, Cell Nucleus/drug effects ; Animals ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Cell Proliferation/drug effects ; Cytoprotection/drug effects ; Gene Expression Regulation/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; NF-E2-Related Factor 2/metabolism ; Neurons/drug effects ; Neurons/pathology ; Oxidative Stress/drug effects ; Rats ; Rats, Sprague-Dawley ; Stroke/metabolism
Czasopismo naukowe
Tytuł:
VEGF-B inhibits hyperglycemia- and Macugen-induced retinal apoptosis.
Autorzy:
Huang D; Center for Medical and Pharmaceutical Research, Binzhou Medical University, Yantai, Shandong, 264003, P. R. China.; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Zhao C; Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University and State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, P. R. China.
Ju R; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Kumar A; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Tian G; Center for Medical and Pharmaceutical Research, Binzhou Medical University, Yantai, Shandong, 264003, P. R. China.
Huang L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Zheng L; Center for Medical and Pharmaceutical Research, Binzhou Medical University, Yantai, Shandong, 264003, P. R. China.; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Li X; Medical Imaging Institute, Shandong Province Characteristical Key Subject, Medical Imaging and Nuclear Medicine, Binzhou Medical University, Yantai, 264003 P. R. China.
Liu L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Wang S; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Ren X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Ye Z; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Chen W; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Xing L; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Chen Q; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Gao Z; Department of Cell Biology, Weifang Medical University, Weifang, 261053 P. R. China.
Mi J; Center for Medical and Pharmaceutical Research, Binzhou Medical University, Yantai, Shandong, 264003, P. R. China.
Tang Z; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Wang B; Medical Imaging Institute, Shandong Province Characteristical Key Subject, Medical Imaging and Nuclear Medicine, Binzhou Medical University, Yantai, 264003 P. R. China.
Zhang S; Center for Medical and Pharmaceutical Research, Binzhou Medical University, Yantai, Shandong, 264003, P. R. China.
Lee C; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
Li X; Center for Medical and Pharmaceutical Research, Binzhou Medical University, Yantai, Shandong, 264003, P. R. China.; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, P. R. China.
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Źródło:
Scientific reports [Sci Rep] 2016 May 18; Vol. 6, pp. 26059. Date of Electronic Publication: 2016 May 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*drug effects
Retinal Diseases/*drug therapy
Retinal Ganglion Cells/*physiology
Vascular Endothelial Growth Factor B/*administration & dosage
Animals ; Aptamers, Nucleotide/toxicity ; Diabetes Mellitus, Experimental/complications ; Mice, Inbred C57BL ; Rats ; Retinal Diseases/physiopathology ; Retinal Ganglion Cells/drug effects ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Effects of UCP4 on the Proliferation and Apoptosis of Chondrocytes: Its Possible Involvement and Regulation in Osteoarthritis.
Autorzy:
Huang Z; Department of Orthopaedic Surgery, Xiaoshan Chinese Medical Hospital, Hangzhou, China.; Department of Orthopaedic Surgery, Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, Hangzhou, China.; Zhejiang Chinese Medical University, Hangzhou, China.; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, China.
Li J; Department of Orthopaedic Surgery, Xiaoshan Chinese Medical Hospital, Hangzhou, China.; Department of Orthopaedic Surgery, Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Du S; Department of Orthopedic Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Chen G; Department of Orthopedic Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Qi Y; Department of Orthopedic Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Huang L; Zhejiang Chinese Medical University, Hangzhou, China.
Xiao L; Zhejiang Chinese Medical University, Hangzhou, China.; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, China.; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Tong P; Zhejiang Chinese Medical University, Hangzhou, China.; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, China.; Department of Orthopaedic Surgery, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
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Źródło:
PloS one [PLoS One] 2016 Mar 02; Vol. 11 (3), pp. e0150684. Date of Electronic Publication: 2016 Mar 02 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Down-Regulation*
Chondrocytes/*pathology
Ion Channels/*genetics
Membrane Transport Proteins/*genetics
Mitochondrial Proteins/*genetics
Osteoarthritis/*genetics
Adult ; Aged ; Animals ; Cartilage, Articular/metabolism ; Cartilage, Articular/pathology ; Cell Proliferation ; Cells, Cultured ; Chondrocytes/metabolism ; Humans ; Ion Channels/metabolism ; Leptin/metabolism ; Male ; Membrane Potential, Mitochondrial ; Membrane Transport Proteins/metabolism ; Middle Aged ; Mitochondrial Proteins/metabolism ; Mitochondrial Uncoupling Proteins ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; RNA Interference ; RNA, Messenger/genetics ; RNA, Small Interfering/genetics ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
N-Acetyl Cysteine Depletes Reactive Oxygen Species and Prevents Dental Monomer-Induced Intrinsic Mitochondrial Apoptosis In Vitro in Human Dental Pulp Cells.
Autorzy:
Jiao Y; State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.; Shaanxi Key Laboratory of Military Stomatology, Xi'an, Shaanxi, PR China.
Ma S; State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.; Shaanxi Key Laboratory of Military Stomatology, Xi'an, Shaanxi, PR China.
Wang Y; Shaanxi Key Laboratory of Military Stomatology, Xi'an, Shaanxi, PR China.; State Key Laboratory of Military Stomatology, Department of Operative Dentistry and Endodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.
Li J; Department of Orthopaedic Oncology, Xijing Hospital Affiliated to the Fourth Military Medical University, Xi'an, PR China.
Shan L; Department of Orthopaedic Surgery, Tangdu Hospital, the Fourth Military Medical University, Xi'an, PR China.
Liu Q; State Key Laboratory of Military Stomatology, Department of Orthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.
Liu Y; State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.; Shaanxi Key Laboratory of Military Stomatology, Xi'an, Shaanxi, PR China.
Song Q; State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.; Shaanxi Key Laboratory of Military Stomatology, Xi'an, Shaanxi, PR China.
Yu F; State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.; Shaanxi Key Laboratory of Military Stomatology, Xi'an, Shaanxi, PR China.
Yu H; State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.; Shaanxi Key Laboratory of Military Stomatology, Xi'an, Shaanxi, PR China.
Liu H; State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.; Shaanxi Key Laboratory of Military Stomatology, Xi'an, Shaanxi, PR China.
Huang L; State Key Laboratory of Military Stomatology, Department of General and Emergency, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.
Chen J; State Key Laboratory of Military Stomatology, Department of Prosthodontics, School of Stomatology, the Fourth Military Medical University, Xi'an, PR China.; Shaanxi Key Laboratory of Military Stomatology, Xi'an, Shaanxi, PR China.
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Źródło:
PloS one [PLoS One] 2016 Jan 25; Vol. 11 (1), pp. e0147858. Date of Electronic Publication: 2016 Jan 25 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acetylcysteine/*pharmacology
Apoptosis/*drug effects
Dental Pulp/*pathology
Mitochondria/*drug effects
Reactive Oxygen Species/*metabolism
Dental Pulp/cytology ; Dental Pulp/metabolism ; Humans ; In Vitro Techniques ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/metabolism
Czasopismo naukowe
Tytuł:
Apoptosis-related microRNA changes in the right atrium induced by remote ischemic perconditioning during valve replacement surgery.
Autorzy:
Hu Q; Department of cardiovascular surgery, Xiangya Hospital, Central-South University, Changsha, Hunan, China, 410078.
Luo W; Department of cardiovascular surgery, Xiangya Hospital, Central-South University, Changsha, Hunan, China, 410078.
Huang L; Department of cardiovascular surgery, Xiangya Hospital, Central-South University, Changsha, Hunan, China, 410078.
Huang R; Department of cardiovascular surgery, Xiangya Hospital, Central-South University, Changsha, Hunan, China, 410078.
Chen R; Department of cardiovascular surgery, Xiangya Hospital, Central-South University, Changsha, Hunan, China, 410078.
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Źródło:
Scientific reports [Sci Rep] 2016 Jan 07; Vol. 6, pp. 18959. Date of Electronic Publication: 2016 Jan 07.
Typ publikacji:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Heart Atria/*metabolism
Heart Valve Diseases/*surgery
MicroRNAs/*metabolism
Adult ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Down-Regulation ; Female ; Heart Valve Diseases/metabolism ; Heart Valve Prosthesis Implantation ; Humans ; Ischemic Preconditioning, Myocardial ; Male ; MicroRNAs/genetics ; Middle Aged ; Myocardium/metabolism ; RNA Interference ; Treatment Outcome
Czasopismo naukowe

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