Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Ukraiński (UK)
Przejdź do strony domowej biblioteki Uniwersytet Ekonomiczny we Wrocławiu Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""INOSITOL 1,4,5-TRISPHOSPHATE"" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-20 z 46
Tytuł:
Xestospongin C, a novel blocker of IP3 receptor, attenuates the increase in cytosolic calcium level and degranulation that is induced by antigen in RBL-2H3 mast cells.
Autorzy:
Oka T; Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Yayoi 1-1-1, Bunkyo-Ku, Tokyo 113-8657, Japan.
Sato K
Hori M
Ozaki H
Karaki H
Pokaż więcej
Źródło:
British journal of pharmacology [Br J Pharmacol] 2002 Apr; Vol. 135 (8), pp. 1959-66.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium/*metabolism
Cell Degranulation/*drug effects
Cytosol/*drug effects
Haptens/*pharmacology
Inositol 1,4,5-Trisphosphate/*metabolism
Mast Cells/*drug effects
Oxazoles/*pharmacology
Receptors, Cytoplasmic and Nuclear/*antagonists & inhibitors
Animals ; Calcium Channels/metabolism ; Cell Membrane Permeability/drug effects ; Cytosol/enzymology ; Cytosol/metabolism ; Dinitrophenols/antagonists & inhibitors ; Dinitrophenols/pharmacology ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/metabolism ; Escin/pharmacology ; Inositol 1,4,5-Trisphosphate/pharmacology ; Inositol 1,4,5-Trisphosphate Receptors ; Macrocyclic Compounds ; Mast Cells/enzymology ; Mast Cells/metabolism ; Rats ; Receptors, Cytoplasmic and Nuclear/metabolism ; Serum Albumin/antagonists & inhibitors ; Serum Albumin/pharmacology ; Tumor Cells, Cultured/drug effects ; Tumor Cells, Cultured/enzymology ; Tumor Cells, Cultured/metabolism ; beta-N-Acetylhexosaminidases/antagonists & inhibitors ; beta-N-Acetylhexosaminidases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand.
Autorzy:
Bosanac I; Division of Molecular and Structural Biology, Ontario Cancer Institute and Department of Medical Biophysics, University of Toronto, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9.
Alattia JR
Mal TK
Chan J
Talarico S
Tong FK
Tong KI
Yoshikawa F
Furuichi T
Iwai M
Michikawa T
Mikoshiba K
Ikura M
Pokaż więcej
Źródło:
Nature [Nature] 2002 Dec 12; Vol. 420 (6916), pp. 696-700. Date of Electronic Publication: 2002 Nov 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium Channels/*chemistry
Calcium Channels/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Receptors, Cytoplasmic and Nuclear/*chemistry
Receptors, Cytoplasmic and Nuclear/*metabolism
Amino Acid Sequence ; Animals ; Binding Sites ; Crystallography, X-Ray ; Inositol 1,4,5-Trisphosphate Receptors ; Ligands ; Mice ; Models, Molecular ; Molecular Sequence Data ; Protein Structure, Secondary ; Protein Structure, Tertiary
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Regulation of nerve growth mediated by inositol 1,4,5-trisphosphate receptors in growth cones.
Autorzy:
Takei K; Calciosignal Net Project, Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Corporation (JST), Bunkyo-Ku, Tokyo 113-0021, Japan. />Shin RM
Inoue T
Kato K
Mikoshiba K
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 1998 Nov 27; Vol. 282 (5394), pp. 1705-8.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium Channels/*metabolism
Growth Cones/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Neurites/*physiology
Receptors, Cytoplasmic and Nuclear/*metabolism
Animals ; Calcium/metabolism ; Calcium Signaling ; Cells, Cultured ; Cerebellum/metabolism ; Chick Embryo ; Ganglia, Spinal/cytology ; Heparin/pharmacology ; Inositol 1,4,5-Trisphosphate Receptors ; Lasers ; Lithium Chloride/pharmacology ; Mice ; Microscopy, Video ; Microsomes/metabolism ; Microtubules/metabolism ; Neurites/drug effects ; Pseudopodia/drug effects ; Pseudopodia/physiology ; Signal Transduction ; Thapsigargin/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Type III InsP3 receptor channel stays open in the presence of increased calcium.
Autorzy:
Hagar RE; Department of Physiology, University of Connecticut Health Center, Farmington 06030, USA. />Burgstahler AD
Nathanson MH
Ehrlich BE
Pokaż więcej
Źródło:
Nature [Nature] 1998 Nov 05; Vol. 396 (6706), pp. 81-4.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Calcium/*metabolism
Calcium Channels/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Adenosine Triphosphate/metabolism ; Allosteric Regulation ; Animals ; Calcium Signaling ; Cell Line ; Cytoplasm/metabolism ; Dogs ; Endoplasmic Reticulum/metabolism ; Inositol 1,4,5-Trisphosphate Receptors ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Elevated [3H]inositol 1,4,5-trisphosphate binding sites and expressed inositol 1,4,5-trisphosphate receptor protein level in platelets of depressed patients.
Autorzy:
Dwivedi Y; Department of Psychiatry, Psychiatric Institute (M/C 912), University of Illinois at Chicago, 60612, USA.
Janicak PG
Pandey GN
Pokaż więcej
Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 1998 Jul; Vol. 138 (1), pp. 47-54.
Typ publikacji:
Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Blood Platelets/*metabolism
Calcium Channels/*metabolism
Depressive Disorder/*blood
Inositol 1,4,5-Trisphosphate/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Adult ; Female ; Humans ; Inositol 1,4,5-Trisphosphate Receptors ; Male ; Tritium
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression.
Autorzy:
Li W; Department of Pharmacology, Howard Hughes Medical Institute, University of California, San Diego, La Jolla 92093-0647, USA.
Llopis J
Whitney M
Zlokarnik G
Tsien RY
Pokaż więcej
Źródło:
Nature [Nature] 1998 Apr 30; Vol. 392 (6679), pp. 936-41.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Gene Expression Regulation*
Nuclear Proteins*
Calcium/*metabolism
Calcium Channels/*biosynthesis
Calcium Channels/*metabolism
DNA-Binding Proteins/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Receptors, Cytoplasmic and Nuclear/*biosynthesis
Receptors, Cytoplasmic and Nuclear/*metabolism
Transcription Factors/*metabolism
Animals ; Calcineurin/metabolism ; Cell Line ; Cell Nucleus/metabolism ; Cytosol/metabolism ; Esterification ; Genes, Reporter ; Humans ; Inositol 1,4,5-Trisphosphate Receptors ; NFATC Transcription Factors ; Signal Transduction ; Transfection ; Tumor Cells, Cultured ; Ultraviolet Rays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation.
Autorzy:
Jayaraman T; Laboratory for Molecular Cardiology, Department of Medicine, Mount Sinai School of Medicine, New York 10029, USA.
Ondrias K
Ondriasová E
Marks AR
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 1996 Jun 07; Vol. 272 (5267), pp. 1492-4.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Calcium Channels/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Phosphotyrosine/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Animals ; Brain/metabolism ; Calcium/metabolism ; Humans ; Inositol 1,4,5-Trisphosphate/pharmacology ; Inositol 1,4,5-Trisphosphate Receptors ; Lipid Bilayers ; Lymphocyte Activation ; Mice ; Phosphorylation ; Protein-Tyrosine Kinases/metabolism ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins/pharmacology ; Proto-Oncogene Proteins c-fyn ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Role of inositol 1,4,5-trisphosphate receptor in ventral signaling in Xenopus embryos.
Autorzy:
Kume S; Mikoshiba Calciosignal Net Project, Exploratory Research for Advanced Technology (ERATO), Japan Science and Technology Corporation (JST), 2-9-3 Shimo-Meguro, Meguro-ku, Tokyo 153, Japan. />Muto A
Inoue T
Suga K
Okano H
Mikoshiba K
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 1997 Dec 12; Vol. 278 (5345), pp. 1940-3.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Body Patterning*
Signal Transduction*
Calcium/*metabolism
Calcium Channels/*metabolism
Embryo, Nonmammalian/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Activins ; Animals ; Antibodies, Blocking ; Antibodies, Monoclonal ; Calcium Channels/immunology ; Cell Differentiation ; Embryonic Development ; Embryonic Induction ; Fibroblast Growth Factor 2/pharmacology ; Gastrula/metabolism ; Gene Expression Regulation, Developmental ; Inhibins/pharmacology ; Inositol 1,4,5-Trisphosphate Receptors ; Receptors, Cytoplasmic and Nuclear/immunology ; Xenopus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor.
Autorzy:
Khan AA; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Soloski MJ
Sharp AH
Schilling G
Sabatini DM
Li SH
Ross CA
Snyder SH
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 1996 Jul 26; Vol. 273 (5274), pp. 503-7.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Apoptosis*
B-Lymphocytes/*cytology
Calcium Channels/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
T-Lymphocytes/*cytology
Amino Acid Sequence ; Animals ; B-Lymphocytes/metabolism ; Base Sequence ; Calcium/metabolism ; Calcium Channels/genetics ; Calcium Channels/immunology ; Cell Line ; Cell Membrane/metabolism ; Cells, Cultured ; DNA, Antisense ; Dexamethasone/pharmacology ; Immunoblotting ; Inositol 1,4,5-Trisphosphate Receptors ; Mice ; Molecular Sequence Data ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, Cytoplasmic and Nuclear/immunology ; T-Lymphocytes/metabolism ; Transfection ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Inositol 1,4,5-trisphosphate activates receptor-mediated calcium entry by two different pathways in hepatocytes.
Autorzy:
Striggow F; Institute of Biochemistry, Otto-von-Guericke-University Magdeburg, Germany.
Bohnensack R
Pokaż więcej
Źródło:
European journal of biochemistry [Eur J Biochem] 1994 May 15; Vol. 222 (1), pp. 229-34.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium/*metabolism
Calcium Channels/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Liver/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Animals ; Inositol 1,4,5-Trisphosphate Receptors ; Ion Transport ; Liver/cytology ; Male ; Manganese/metabolism ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
IP3 receptor: localization to plasma membrane of T cells and cocapping with the T cell receptor.
Autorzy:
Khan AA; Johns Hopkins University School of Medicine, Department of Neuroscience, Baltimore, MD 21205.
Steiner JP
Klein MG
Schneider MF
Snyder SH
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 1992 Aug 07; Vol. 257 (5071), pp. 815-8.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Calcium Channels*
Receptors, Cytoplasmic and Nuclear*
Antigens, Differentiation, T-Lymphocyte/*metabolism
Calcium/*metabolism
Cell Membrane/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Receptors, Antigen, T-Cell/*metabolism
Receptors, Cell Surface/*metabolism
T-Lymphocytes/*immunology
Antigens, CD/metabolism ; Antigens, Differentiation, T-Lymphocyte/analysis ; Burkitt Lymphoma ; CD3 Complex ; Cell Line ; Cells, Cultured ; Concanavalin A/pharmacology ; Fluorescent Antibody Technique ; Humans ; Inositol 1,4,5-Trisphosphate Receptors ; Kinetics ; Receptors, Antigen, T-Cell/analysis ; Receptors, Cell Surface/analysis ; Second Messenger Systems
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Parathyroid hormone increases the sensitivity of inositol trisphosphate receptors by a mechanism that is independent of cyclic AMP.
Autorzy:
Tovey SC; Department of Pharmacology, Tennis Court Road, Cambridge CB2 1PD, UK.
Goraya TA
Taylor CW
Pokaż więcej
Źródło:
British journal of pharmacology [Br J Pharmacol] 2003 Jan; Vol. 138 (1), pp. 81-90.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium Channels/*metabolism
Cyclic AMP/*metabolism
Parathyroid Hormone/*pharmacology
Receptors, Cytoplasmic and Nuclear/*metabolism
Calcium/metabolism ; Cell Line ; Humans ; Inositol 1,4,5-Trisphosphate/pharmacology ; Inositol 1,4,5-Trisphosphate Receptors ; Receptors, Cytoplasmic and Nuclear/agonists
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Irregular spiking in free calcium concentration in single, human platelets. Regulation by modulation of the inositol trisphosphate receptors.
Autorzy:
van Gorp RM; Department of Biochemistry, University of Maastricht, the Netherlands.
Feijge MA
Vuist WM
Rook MB
Heemskerk JW
Pokaż więcej
Źródło:
European journal of biochemistry [Eur J Biochem] 2002 Mar; Vol. 269 (5), pp. 1543-52.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets/*metabolism
Calcium/*metabolism
Calcium Channels/*physiology
Receptors, Cytoplasmic and Nuclear/*physiology
Alprostadil/pharmacology ; Cyclic AMP/biosynthesis ; Humans ; Inositol 1,4,5-Trisphosphate/biosynthesis ; Inositol 1,4,5-Trisphosphate Receptors ; Thimerosal/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.
Autorzy:
Young AP; Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
Schlisio S
Minamishima YA
Zhang Q
Li L
Grisanzio C
Signoretti S
Kaelin WG Jr
Pokaż więcej
Źródło:
Nature cell biology [Nat Cell Biol] 2008 Mar; Vol. 10 (3), pp. 361-9. Date of Electronic Publication: 2008 Feb 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cellular Senescence*
Gene Expression Regulation*
Calcium Channels/*metabolism
Hypoxia-Inducible Factor 1/*metabolism
Membrane Glycoproteins/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Retinoblastoma Protein/*metabolism
Von Hippel-Lindau Tumor Suppressor Protein/*physiology
Animals ; Cells, Cultured ; Fibroblasts/metabolism ; Inositol 1,4,5-Trisphosphate Receptors ; Mice ; Mice, Transgenic ; Mutation ; Oxygen/metabolism ; Phenotype ; Retroviridae/metabolism ; Von Hippel-Lindau Tumor Suppressor Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Circadian rhythms. Daily watch on metabolism.
Autorzy:
Imaizumi T; Division of Biological Sciences, Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA 92093-0116, USA. />Kay SA
Schroeder JI
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2007 Dec 14; Vol. 318 (5857), pp. 1730-1. Date of Electronic Publication: 2007 Nov 15.
Typ publikacji:
Comment; Journal Article
MeSH Terms:
Circadian Rhythm*
Arabidopsis/*metabolism
Calcium/*metabolism
DNA-Binding Proteins/*metabolism
Glucose/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Animals ; Arabidopsis/genetics ; Biological Clocks ; Calcium Signaling ; Cyclic ADP-Ribose/metabolism ; Feedback, Physiological ; Gene Expression Regulation ; Gene Expression Regulation, Plant ; Heme/metabolism ; Homeostasis ; Humans ; Inositol 1,4,5-Trisphosphate/metabolism ; Metabolic Networks and Pathways ; Nuclear Receptor Subfamily 1, Group D, Member 1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Basic properties of an inositol 1,4,5-trisphosphate-gated channel in carp olfactory cilia.
Autorzy:
Cadiou H; UMR 6522 CNRS, IFRMP 23,Université de Rouen, F-76821 Mont Saint Aignan, France.
Sienaert I
Vanlingen S
Parys JB
Molle G
Duclohier H
Pokaż więcej
Źródło:
The European journal of neuroscience [Eur J Neurosci] 2000 Aug; Vol. 12 (8), pp. 2805-11.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium Channels/*metabolism
Carps/*physiology
Cilia/*physiology
Ion Channel Gating/*physiology
Olfactory Mucosa/*physiology
Receptors, Cytoplasmic and Nuclear/*metabolism
Animals ; Anticoagulants/pharmacology ; Barium/pharmacokinetics ; Blotting, Western ; Calcium/metabolism ; Calcium/pharmacology ; Calcium Channels/analysis ; Calcium Channels/immunology ; Cerebellum/chemistry ; Cilia/chemistry ; Heparin/pharmacology ; Indicators and Reagents/pharmacology ; Inositol 1,4,5-Trisphosphate/physiology ; Inositol 1,4,5-Trisphosphate Receptors ; Ion Channel Gating/drug effects ; Lipid Bilayers ; Mammals ; Membrane Potentials/drug effects ; Membrane Potentials/physiology ; Microsomes/chemistry ; Microsomes/physiology ; Myocardium/chemistry ; Olfactory Mucosa/chemistry ; Patch-Clamp Techniques ; Receptors, Cytoplasmic and Nuclear/analysis ; Receptors, Cytoplasmic and Nuclear/immunology ; Ruthenium Red/pharmacology ; Species Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Signal transduction. Calcium entry signals--trickles and torrents.
Autorzy:
Gill DL; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. />Spassova MA
Soboloff J
Pokaż więcej
Źródło:
Science (New York, N.Y.) [Science] 2006 Jul 14; Vol. 313 (5784), pp. 183-4.
Typ publikacji:
Comment; Journal Article
MeSH Terms:
Calcium Signaling*
Ion Channel Gating*
Calcium/*metabolism
Calcium Channels/*metabolism
Cell Membrane/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Animals ; Calcium Channels/chemistry ; Cytoplasm/metabolism ; Endoplasmic Reticulum/metabolism ; Humans ; Inositol 1,4,5-Trisphosphate Receptors ; Membrane Proteins/chemistry ; Membrane Proteins/metabolism ; Receptors, Cytoplasmic and Nuclear/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 46

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies