Autor: "Im YK" - OpacWWW - Prolib Integro

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Tytuł:: The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner.
Autorzy:: Im YK; Department of Oncology, Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada.
La Selva R; Department of Oncology, Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada.
Gandin V; Department of Oncology, Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada.
Ha JR; Department of Oncology, Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada.
Sabourin V; Department of Oncology, Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada.
Sonenberg N; Goodman Cancer Research Centre, Montreal, Quebec, Canada.
Pawson T; Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
Topisirovic I; Department of Oncology, Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada.
Ursini-Siegel J; Department of Oncology, Lady Davis Institute for Medical Research, McGill University, Montreal, Quebec, Canada.; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2015 Mar 26; Vol. 34 (13), pp. 1729-35. Date of Electronic Publication: 2014 May 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Protein Biosynthesis*
Adaptor Proteins, Signal Transducing/*physiology
Breast Neoplasms/*blood supply
Neovascularization, Pathologic/*etiology
Phosphoproteins/*physiology
Proto-Oncogene Proteins c-akt/*physiology
Shc Signaling Adaptor Proteins/*physiology
Signal Transduction/*physiology
Vascular Endothelial Growth Factor A/*genetics
Animals ; Cell Cycle Proteins ; Female ; Humans ; Mice ; Phosphatidylinositol 3-Kinases/physiology ; RNA, Messenger/genetics ; Src Homology 2 Domain-Containing, Transforming Protein 1 ; Src Homology 2 Domain-Containing, Transforming Protein 3 ; Vascular Endothelial Growth Factor A/biosynthesis

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