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Wyświetlanie 1-20 z 78
Tytuł:
Functional conservation of the apoptotic machinery from coral to man: the diverse and complex Bcl-2 and caspase repertoires of Acropora millepora.
Autorzy:
Moya A; ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, Queensland, 4811, Australia. .
Sakamaki K; Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto, 606-8501, Japan. .
Mason BM; ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, Queensland, 4811, Australia. .; Comparative Genomics Centre and Department of Molecular and Cell Biology, James Cook University, Townsville, Queensland, 4811, Australia. .
Huisman L; ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, Queensland, 4811, Australia. .; Section of Computational Science, Universiteit van Amsterdam, Science Park 904, 1098, XH, Amsterdam, The Netherlands. .
Forêt S; ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, Queensland, 4811, Australia. .; Evolution, Ecology and Genetics, Research School of Biology, Australian National University, Bldg. 46, Canberra, ACT, 0200, Australia. .
Weiss Y; ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, Queensland, 4811, Australia. .; Comparative Genomics Centre and Department of Molecular and Cell Biology, James Cook University, Townsville, Queensland, 4811, Australia. .
Bull TE; Comparative Genomics Centre and Department of Molecular and Cell Biology, James Cook University, Townsville, Queensland, 4811, Australia. .
Tomii K; Biotechnology Research Institute for Drug Discovery, Department of Life Science and Biotechnology, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, 135-0064, Japan. k.
Imai K; Biotechnology Research Institute for Drug Discovery, Department of Life Science and Biotechnology, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, 135-0064, Japan. kenichiro.imai@aist.go.jp.
Hayward DC; Evolution, Ecology and Genetics, Research School of Biology, Australian National University, Bldg. 46, Canberra, ACT, 0200, Australia. .
Ball EE; ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, Queensland, 4811, Australia. .; Evolution, Ecology and Genetics, Research School of Biology, Australian National University, Bldg. 46, Canberra, ACT, 0200, Australia. .
Miller DJ; ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, Queensland, 4811, Australia. .; Comparative Genomics Centre and Department of Molecular and Cell Biology, James Cook University, Townsville, Queensland, 4811, Australia. .
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Źródło:
BMC genomics [BMC Genomics] 2016 Jan 16; Vol. 17, pp. 62. Date of Electronic Publication: 2016 Jan 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Evolution, Molecular*
Apoptosis/*genetics
Caspase 8/*genetics
Proto-Oncogene Proteins c-bcl-2/*genetics
Amino Acid Sequence/genetics ; Animals ; Anthozoa/genetics ; Conserved Sequence/genetics ; Drosophila/genetics ; Phylogeny
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Bmf is a possible mediator in histone deacetylase inhibitors FK228 and CBHA-induced apoptosis.
Autorzy:
Zhang Y; Division of Molecular Oncology and Molecular Diagnosis, Graduate School of Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
Adachi M
Kawamura R
Imai K
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Źródło:
Cell death and differentiation [Cell Death Differ] 2006 Jan; Vol. 13 (1), pp. 129-40.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Histone Deacetylase Inhibitors*
Adaptor Proteins, Signal Transducing/*metabolism
Apoptosis/*drug effects
Apoptosis/*physiology
Cinnamates/*pharmacology
Depsipeptides/*pharmacology
Enzyme Inhibitors/*pharmacology
Acetylation ; Adaptor Proteins, Signal Transducing/antagonists & inhibitors ; Adaptor Proteins, Signal Transducing/genetics ; Antineoplastic Agents/pharmacology ; Base Sequence ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/physiology ; Cisplatin/pharmacology ; Genes, Reporter/drug effects ; Histones/chemistry ; Histones/metabolism ; Humans ; Jurkat Cells ; RNA Interference ; RNA, Small Interfering/genetics ; Transcriptional Activation/drug effects ; Transfection
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Inhibition of the 53BP2S-mediated apoptosis by nuclear factor kappaB and Bcl-2 family proteins.
Autorzy:
Takahashi N; Department of Molecular and Cellular Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi 467-8601, Japan.
Kobayashi S
Kajino S
Imai K
Tomoda K
Shimizu S
Okamoto T
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Źródło:
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2005 Aug; Vol. 10 (8), pp. 803-11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Carrier Proteins/*pharmacology
NF-kappa B/*metabolism
Proto-Oncogene Proteins c-bcl-2/*metabolism
Apoptosis Regulatory Proteins ; Benzimidazoles/analysis ; Caspase 9 ; Caspases/metabolism ; Cell Survival ; Ecdysterone/analogs & derivatives ; Ecdysterone/pharmacology ; Electrophoretic Mobility Shift Assay ; Green Fluorescent Proteins/metabolism ; Humans ; Models, Biological ; Organic Chemicals/analysis ; Pancreatic Neoplasms ; Time Factors ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
53BP2 induces apoptosis through the mitochondrial death pathway.
Autorzy:
Kobayashi S; Department of Molecular and Cellular Biology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi 467-8601, Japan.
Kajino S
Takahashi N
Kanazawa S
Imai K
Hibi Y
Ohara H
Itoh M
Okamoto T
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Źródło:
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2005 Mar; Vol. 10 (3), pp. 253-60.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*physiology
Carrier Proteins/*metabolism
Ecdysterone/*analogs & derivatives
Mitochondria/*physiology
Apoptosis Regulatory Proteins ; Caspase 9 ; Caspases/metabolism ; Cytosol/metabolism ; Ecdysterone/metabolism ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Identification of SCN3B as a novel p53-inducible proapoptotic gene.
Autorzy:
Adachi K; Department of Molecular Biology, Cancer Research Institute, Sapporo Medical University School of Medicine, S-1, W-17, Chuo-ku, Sapporo 060-8556, Japan.
Toyota M
Sasaki Y
Yamashita T
Ishida S
Ohe-Toyota M
Maruyama R
Hinoda Y
Saito T
Imai K
Kudo R
Tokino T
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Źródło:
Oncogene [Oncogene] 2004 Oct 14; Vol. 23 (47), pp. 7791-8.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*genetics
Sodium Channels/*genetics
Tumor Suppressor Protein p53/*metabolism
Animals ; Binding Sites ; Cell Line, Tumor ; Exons/genetics ; Fibroblasts ; Genetic Therapy ; Humans ; Introns/genetics ; Mice ; Mice, Knockout ; Sodium Channels/metabolism ; Tumor Suppressor Protein p53/deficiency ; Tumor Suppressor Protein p53/genetics ; Voltage-Gated Sodium Channel beta-3 Subunit
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The proapoptotic BH3-only protein BAD transduces cell death signals independently of its interaction with Bcl-2.
Autorzy:
Adachi M; Division of Molecular Oncology and Molecular Diagnosis, Graduate School of Medicine, Sapporo Medical University, Sapporo, Japan. />Imai K
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Źródło:
Cell death and differentiation [Cell Death Differ] 2002 Nov; Vol. 9 (11), pp. 1240-7.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis/*physiology
Carrier Proteins/*physiology
Proto-Oncogene Proteins c-bcl-2/*metabolism
Signal Transduction/*physiology
Amino Acid Substitution ; Animals ; COS Cells ; Carrier Proteins/genetics ; Humans ; Mitochondria/metabolism ; Mutation ; bcl-Associated Death Protein ; bcl-X Protein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Differential gene expression of sFRP-1 and apoptosis in pulmonary emphysema.
Autorzy:
Imai K; Division of Molecular Medicine, Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
D'Armiento J
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Źródło:
Chest [Chest] 2002 Mar; Vol. 121 (3 Suppl), pp. 7S.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression*
Apoptosis/*genetics
Glycoproteins/*genetics
Lung/*pathology
Pulmonary Emphysema/*genetics
Animals ; Gene Expression Profiling ; Humans ; Intracellular Signaling Peptides and Proteins ; Mice ; Pulmonary Emphysema/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: potential application to gene therapy of colorectal cancer.
Autorzy:
Sasaki Y; Department of Molecular Biology, Cancer Research Institute, Sapporo Medical University School of Medicine, S-1, W-17, Chuo-ku, Sapporo, 060-8556 Japan.
Morimoto I
Ishida S
Yamashita T
Imai K
Tokino T
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Źródło:
Gene therapy [Gene Ther] 2001 Sep; Vol. 8 (18), pp. 1401-8.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genes, p53*
Membrane Proteins*
Adenoviridae/*genetics
Apoptosis/*genetics
Colorectal Neoplasms/*therapy
Genetic Therapy/*methods
Genetic Vectors/*administration & dosage
Animals ; Antineoplastic Agents/pharmacology ; Carcinogenicity Tests ; Colorectal Neoplasms/pathology ; DNA-Binding Proteins/genetics ; Doxorubicin/pharmacology ; Genes, Tumor Suppressor ; Humans ; Mice ; Mice, Nude ; Nuclear Proteins/genetics ; Phosphoproteins/genetics ; Trans-Activators/genetics ; Transcription Factors ; Transduction, Genetic/methods ; Tumor Cells, Cultured ; Tumor Protein p73 ; Tumor Suppressor Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protein kinase Calpha promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorage.
Autorzy:
Okuda H; The First Department of Internal Medicine, Sapporo Medical University School of Medicine, S1 W16, Chuo-Ku, Sapporo 060-8543, Japan.
Adachi M
Miyazawa M
Hinoda Y
Imai K
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Źródło:
Oncogene [Oncogene] 1999 Sep 30; Vol. 18 (40), pp. 5604-9.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma/*enzymology
Apoptosis/*physiology
Cell Adhesion/*physiology
Isoenzymes/*physiology
Neoplasm Proteins/*physiology
Protein Kinase C/*physiology
Stomach Neoplasms/*enzymology
Adenocarcinoma/pathology ; Apoptosis/drug effects ; Caspase 3 ; Caspases/metabolism ; Cell Adhesion/drug effects ; Enzyme Activation/drug effects ; Humans ; Isoenzymes/genetics ; MAP Kinase Signaling System/drug effects ; Protein Kinase C-alpha ; Recombinant Fusion Proteins/physiology ; Stomach Neoplasms/pathology ; Tetradecanoylphorbol Acetate/pharmacology ; Transfection ; Tumor Cells, Cultured/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Anti-cell death activity promotes pulmonary metastasis of melanoma cells.
Autorzy:
Takaoka A; The First Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan.
Adachi M
Okuda H
Sato S
Yawata A
Hinoda Y
Takayama S
Reed JC
Imai K
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Źródło:
Oncogene [Oncogene] 1997 Jun 19; Vol. 14 (24), pp. 2971-7.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Apoptosis/*physiology
Carrier Proteins/*physiology
Lung Neoplasms/*secondary
Melanoma, Experimental/*secondary
Proto-Oncogene Proteins c-bcl-2/*physiology
Animals ; Carrier Proteins/biosynthesis ; Carrier Proteins/genetics ; Cell Death/physiology ; Cell Division/physiology ; Cell Movement/physiology ; DNA-Binding Proteins ; Lung Neoplasms/pathology ; Melanoma, Experimental/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplasm Invasiveness ; Proto-Oncogene Proteins c-bcl-2/biosynthesis ; Proto-Oncogene Proteins c-bcl-2/genetics ; Transcription Factors ; Transfection
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 78

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