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Wyszukujesz frazę ""Lysine"" wg kryterium: Temat


Tytuł:
Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes.
Autorzy:
Terajima M; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Taga Y; Nippi Research Institute of Biomatrix, Ibaraki, Japan.
Nakamura T; Department of Pharmacology, Kansai Medical University, Osaka, Japan.
Guo HF; Department of Molecular and Cellular Biochemistry, University of Kentucky, Kentucky, USA.
Kayashima Y; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Maeda-Smithies N; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Parag-Sharma K; Graduate Curriculum in Cell Biology & Physiology, Biological & Biomedical Sciences Program, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kim JS; Department of Molecular and Cellular Biochemistry, University of Kentucky, Kentucky, USA.
Amelio AL; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Cell Biology and Physiology, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Biomedical Research Imaging Center, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, Cancer Cell Biology Program, UNC School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Mizuno K; Nippi Research Institute of Biomatrix, Ibaraki, Japan.
Kurie JM; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Yamauchi M; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. mitsuo_.; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, 385 S Columbia Street, Koury Oral Health Sciences, Chapel Hill, NC, 27599, USA. mitsuo_.
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Źródło:
Scientific reports [Sci Rep] 2022 Aug 22; Vol. 12 (1), pp. 14256. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Collagen Type I*/metabolism
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase*/genetics
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase*/metabolism
Collagen/metabolism ; Hydroxylation ; Lysine/metabolism ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł:
Unraveling the Role of the Tyrosine Tetrad from the Binding Site of the Epigenetic Writer MLL3 in the Catalytic Mechanism and Methylation Multiplicity.
Autorzy:
Blanco-Esperguez K; Departamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, República 275, Santiago 8370146, Chile.
Tuñón I; Departamento de Química Física, Universidad de Valencia, 46100 Burjasot, Spain.
Kästner J; Institut für Theoretische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany.
Mendizábal F; Departamento de Química, Facultad de Ciencias, Universidad de Chile, P.O. Box 653, Las Palmeras 3425, Ñuñoa, Santiago 7800003, Chile.
Miranda-Rojas S; Departamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, República 275, Santiago 8370146, Chile.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 07; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 07.
Typ publikacji:
Journal Article
MeSH Terms:
Histone-Lysine N-Methyltransferase*/metabolism
Histones*/metabolism
Alanine/genetics ; Binding Sites ; Epigenesis, Genetic ; Lysine/metabolism ; Methylation ; Phenylalanine/metabolism ; Tyrosine/metabolism ; Water/metabolism
Czasopismo naukowe
Tytuł:
Expression of the histone lysine methyltransferases SETD1B, SETDB1, SETD2, and CFP1 exhibits significant changes in the oocytes and granulosa cells of aged mouse ovaries.
Autorzy:
Bilmez Y; Department of Histology and Embryology, Akdeniz University School of Medicine, Campus, 07070, Antalya, Turkey.
Talibova G; Department of Histology and Embryology, Akdeniz University School of Medicine, Campus, 07070, Antalya, Turkey.
Ozturk S; Department of Histology and Embryology, Akdeniz University School of Medicine, Campus, 07070, Antalya, Turkey. .
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Źródło:
Histochemistry and cell biology [Histochem Cell Biol] 2022 Jul; Vol. 158 (1), pp. 79-95. Date of Electronic Publication: 2022 Apr 20.
Typ publikacji:
Journal Article
MeSH Terms:
Histone-Lysine N-Methyltransferase*/genetics
Histone-Lysine N-Methyltransferase*/metabolism
Histones*/metabolism
Ovary*/metabolism
Trans-Activators*/metabolism
Animals ; Female ; Granulosa Cells/metabolism ; Lysine/metabolism ; Mice ; Oocytes/metabolism ; Sexual Maturation
Czasopismo naukowe
Tytuł:
Influence of N -Lysine Acetylation on the Formation of Protein Aggregates and Antibiotic Persistence in E. coli .
Autorzy:
Stojowska-Swędrzyńska K; Department of General and Medical Biochemistry, Faculty of Biology, University of Gdansk, Wita Stwosza 59, 80-308 Gdansk, Poland.
Kuczyńska-Wiśnik D; Department of General and Medical Biochemistry, Faculty of Biology, University of Gdansk, Wita Stwosza 59, 80-308 Gdansk, Poland.
Laskowska E; Department of General and Medical Biochemistry, Faculty of Biology, University of Gdansk, Wita Stwosza 59, 80-308 Gdansk, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 12; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Escherichia coli*/genetics
Lysine*
Acetylation ; Protein Aggregates ; Anti-Bacterial Agents/pharmacology
Czasopismo naukowe
Tytuł:
Phosphorylated Adapter RNA Export Protein Is Methylated at Lys 381 by an Methyltransferase-like 21C (METTL21C).
Autorzy:
Ke M; School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.
Yu X; School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.
Sun Y; School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.
Han S; School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.
Wang L; School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.; Engineering Research Center of Quality Improvement and Safety Control of Qinba Special Meat Products, Universities of Shaanxi Province, Hanzhong 723001, China.
Zhang T; School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.; Engineering Research Center of Quality Improvement and Safety Control of Qinba Special Meat Products, Universities of Shaanxi Province, Hanzhong 723001, China.; Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723001, China.; Shaanxi Union Research Center of University and Enterprise for Zhenba Bacon, Hanzhong 723001, China.
Zeng W; School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.; Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723001, China.
Lu H; School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.; Engineering Research Center of Quality Improvement and Safety Control of Qinba Special Meat Products, Universities of Shaanxi Province, Hanzhong 723001, China.; Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723001, China.; Shaanxi Union Research Center of University and Enterprise for Zhenba Bacon, Hanzhong 723001, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 21; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
RNA*
Lysine*
Chick Embryo ; Humans ; Animals ; Mice ; Chromatography, Liquid ; Proteomics ; Tandem Mass Spectrometry ; Adaptor Proteins, Signal Transducing ; Chickens ; Methyltransferases/genetics
Czasopismo naukowe
Tytuł:
In-silico guided chemical exploration of KDM4A fragments hits.
Autorzy:
Lombino J; Molecular Informatics Group, Fondazione Ri.MED, 90100, Palermo, Italy.; C4T S.r.l., Colosseum Combinatorial Chemistry Center, 00133, Rome, Italy.
Vallone R; Structural Biology and Biophysics Unit, Fondazione Ri.MED, 90100, Palermo, Italy.
Cimino M; Target Identification and Screening Group, Fondazione Ri.MED, 90100, Palermo, Italy.
Gulotta MR; Molecular Informatics Group, Fondazione Ri.MED, 90100, Palermo, Italy.
De Simone G; Molecular Informatics Group, Fondazione Ri.MED, 90100, Palermo, Italy.
Morando MA; Structural Biology and Biophysics Unit, Fondazione Ri.MED, 90100, Palermo, Italy.
Sabbatella R; Structural Biology and Biophysics Unit, Fondazione Ri.MED, 90100, Palermo, Italy.
Di Martino S; Medicinal Chemistry Group, Fondazione Ri.MED, 90100, Palermo, Italy.
Fogazza M; Target Identification and Screening Group, Fondazione Ri.MED, 90100, Palermo, Italy.; Axxam SpA, 20091, Bresso, MI, Italy.
Sarno F; Dipartimento di Medicina di Precisione, Università degli Studi della Campania 'L. Vanvitelli', 80100, Naples, Italy.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, 9713, Groningen, GZ, The Netherlands.
Coronnello C; Advanced Data Analysis Group, Fondazione Ri.MED, 90100, Palermo, Italy.
De Rosa M; Medicinal Chemistry Group, Fondazione Ri.MED, 90100, Palermo, Italy.
Cipollina C; Target Identification and Screening Group, Fondazione Ri.MED, 90100, Palermo, Italy.
Altucci L; Dipartimento di Medicina di Precisione, Università degli Studi della Campania 'L. Vanvitelli', 80100, Naples, Italy.; BIOGEM, 83031, Ariano Irpino, AV, Italy.; IEOS-CNR, 80100, Naples, Italy.
Perricone U; Molecular Informatics Group, Fondazione Ri.MED, 90100, Palermo, Italy. .
Alfano C; Structural Biology and Biophysics Unit, Fondazione Ri.MED, 90100, Palermo, Italy. .
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Źródło:
Clinical epigenetics [Clin Epigenetics] 2023 Dec 21; Vol. 15 (1), pp. 197. Date of Electronic Publication: 2023 Dec 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Jumonji Domain-Containing Histone Demethylases*/genetics
Jumonji Domain-Containing Histone Demethylases*/metabolism
Lysine*/metabolism
Humans ; DNA Methylation ; Histones/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
GBDT_KgluSite: An improved computational prediction model for lysine glutarylation sites based on feature fusion and GBDT classifier.
Autorzy:
Liu X; School of Medical Informatics and Engineering, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China. .
Zhu B; Cancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China.; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China.
Dai XW; School of Medical Informatics and Engineering, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China.
Xu ZA; School of Life Sciences, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China.
Li R; School of Life Sciences, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China.
Qian Y; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China.
Lu YP; School of Humanities and Arts, China University of Mining and Technology, Xuzhou, Jiangsu, 221116, China.
Zhang W; School of Medical Informatics and Engineering, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China.
Liu Y; Cancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China. .; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China. .
Zheng J; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China. .; Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, China. .
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Źródło:
BMC genomics [BMC Genomics] 2023 Dec 11; Vol. 24 (1), pp. 765. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Lysine*/metabolism
Proteins*/metabolism
Amino Acid Sequence ; Protein Processing, Post-Translational ; Mitochondria/metabolism ; Computational Biology/methods
Czasopismo naukowe
Tytuł:
Cancer Associated PRDM9: Implications for Linking Genomic Instability and Meiotic Recombination.
Autorzy:
Ladias P; Laboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45 110 Ioannina, Greece.
Markopoulos GS; Neurosurgical Institute, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45 110 Ioannina, Greece.
Kostoulas C; Laboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45 110 Ioannina, Greece.
Bouba I; Laboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45 110 Ioannina, Greece.
Markoula S; Department of Neurology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45 110 Ioannina, Greece.
Georgiou I; Laboratory of Medical Genetics in Clinical Practice, Faculty of Medicine, School of Health Sciences, University of Ioannina, 45 110 Ioannina, Greece.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 20; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Genomic Instability*
Histone-Lysine N-Methyltransferase*/genetics
Histone-Lysine N-Methyltransferase*/metabolism
Neoplasms*/genetics
Neoplasms*/metabolism
Humans ; Homologous Recombination ; Meiosis
Czasopismo naukowe
Tytuł:
SETD2 deficiency promotes renal fibrosis through the TGF-β/Smad signalling pathway in the absence of VHL.
Autorzy:
Liu C; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Ni L; Department of Nursing, Shanghai East Hospital, Tongji University, Shanghai, China.
Li X; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Rao H; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Feng W; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Zhu Y; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Zhang W; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Ma C; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Xu Y; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Gui L; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Wang Z; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Aji R; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Xu J; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Gao WQ; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Li L; State Key Laboratory of Systems Medicine for Cancer, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Nov; Vol. 13 (11), pp. e1468.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Histone-Lysine N-Methyltransferase*/genetics
Histone-Lysine N-Methyltransferase*/metabolism
Renal Insufficiency, Chronic*/pathology
Transforming Growth Factor beta*/metabolism
Animals ; Humans ; Mice ; Fibrosis ; Kidney/metabolism ; Smad Proteins/metabolism ; Von Hippel-Lindau Tumor Suppressor Protein/metabolism
Czasopismo naukowe
Tytuł:
NSD3 in Cancer: Unraveling Methyltransferase-Dependent and Isoform-Specific Functions.
Autorzy:
Nuñez Y; Biomedical Science Research Laboratory, Department of Basic Sciences, Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepción 4090541, Chile.; Biochemistry, Faculty of Pharmacy, Universidad de Concepción, Concepción 4070383, Chile.
Vera S; Biomedical Science Research Laboratory, Department of Basic Sciences, Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepción 4090541, Chile.
Baeza V; Biomedical Science Research Laboratory, Department of Basic Sciences, Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepción 4090541, Chile.
Gonzalez-Pecchi V; Biomedical Science Research Laboratory, Department of Basic Sciences, Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepción 4090541, Chile.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 12; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Histone-Lysine N-Methyltransferase*/metabolism
Nuclear Proteins*/metabolism
Neoplasms*/enzymology
Neoplasms*/pathology
Humans ; Male ; Carcinoma/enzymology ; Leukemia/enzymology ; Oncogenes ; Protein Isoforms/genetics
Czasopismo naukowe
Tytuł:
Protein lysine acetylation does not contribute to the high rates of fatty acid oxidation seen in the post-ischemic heart.
Autorzy:
Ketema EB; Cardiovascular Research Centre, Department of Pediatrics, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, AB, T6G 2S2, Canada.
Ahsan M; Cardiovascular Research Centre, Department of Pediatrics, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, AB, T6G 2S2, Canada.
Zhang L; Cardiovascular Research Centre, Department of Pediatrics, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, AB, T6G 2S2, Canada.
Karwi QG; Cardiovascular Research Centre, Department of Pediatrics, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, AB, T6G 2S2, Canada.
Lopaschuk GD; Cardiovascular Research Centre, Department of Pediatrics, University of Alberta, 423 Heritage Medical Research Centre, Edmonton, AB, T6G 2S2, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 12; Vol. 14 (1), pp. 1193. Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Myocardium*/metabolism
Lysine*/metabolism
Rats ; Animals ; Rats, Sprague-Dawley ; Acetylation ; Fatty Acids/metabolism ; Heart/physiology ; Ischemia/metabolism ; Glycolysis/physiology ; Glucose/metabolism ; Oxidation-Reduction ; Palmitates/metabolism
Czasopismo naukowe
Tytuł:
Dysregulation of extracellular matrix and Lysyl Oxidase in Ehlers-Danlos syndrome type IV skin fibroblasts.
Autorzy:
Foehr R; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA.
Anderson K; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA.
Dombrowski O; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA.
Foehr A; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA.
Foehr ED; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA. .
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Źródło:
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2024 Jan 05; Vol. 19 (1), pp. 9. Date of Electronic Publication: 2024 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Protein-Lysine 6-Oxidase*/genetics
Ehlers-Danlos Syndrome*/genetics
Humans ; Skin ; Extracellular Matrix ; Fibrosis
Czasopismo naukowe
Tytuł:
The bactericidal and antibiofilm effects of a lysine-substituted hybrid peptide, CM-10K14K, on biofilm-forming Staphylococcus epidermidis.
Autorzy:
Klubthawee N; Department of Medical Technology, Faculty of Allied Health Sciences, Thammasat University, Khlong Luang, 12120, Pathum Thani, Thailand.
Wongchai M; Graduate Program in Biomedical Sciences, Faculty of Allied Health Sciences, Thammasat University, Khlong Luang, 12120, Pathum Thani, Thailand.
Aunpad R; Graduate Program in Biomedical Sciences, Faculty of Allied Health Sciences, Thammasat University, Khlong Luang, 12120, Pathum Thani, Thailand. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 14; Vol. 13 (1), pp. 22262. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
Staphylococcus epidermidis*
Lysine*/pharmacology
Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Staphylococcus ; Biofilms ; Microbial Sensitivity Tests
Czasopismo naukowe
Tytuł:
Evolution of lysine-specific demethylase 1 and REST corepressor gene families and their molecular interaction.
Autorzy:
Olivares-Costa M; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.; Departamento de Ciencias Biomédica, Facultad de Medicina, Universidad Católica del Norte, Coquimbo, Chile.
Oyarzún GM; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Biological Sciences, Columbia University, New York, NY, USA.; Department of Genetics and Development, Columbia University Medical Center, New York, NY, USA.
Verbel-Vergara D; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
González MP; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Arancibia D; Departamento de Ciencias Farmacéuticas, Facultad de Ciencias, Universidad Católica del Norte, Antofagasta, Chile.
Andrés ME; Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile. .
Opazo JC; Facultad de Medicina y Ciencia, Universidad San Sebastián, Valdivia, Chile. .; Integrative Biology Group, Valdivia, Chile. .; Millennium Nucleus of Ion Channel-Associated Diseases (MiNICAD), Valdivia, Chile. .
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Źródło:
Communications biology [Commun Biol] 2023 Dec 14; Vol. 6 (1), pp. 1267. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lysine*
Histone Demethylases*/genetics
Histone Demethylases*/metabolism
Animals ; Histones/metabolism ; Vertebrates/genetics ; Co-Repressor Proteins/genetics ; Co-Repressor Proteins/metabolism
Czasopismo naukowe
Tytuł:
Targeting antimalarial metabolites from the actinomycetes associated with the Red Sea sponge Callyspongia siphonella using a metabolomic method.
Autorzy:
Gamaleldin NM; Department of Microbiology, Faculty of Pharmacy, the British University in Egypt (BUE), Cairo, 11837, Egypt.
Bahr HS; Department of Pharmacognosy, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt.
Millán-Aguiñaga N; Facultad de Ciencias Marinas, Universidad Autónoma de Baja California, Ensenada, 22860, Baja California, México.
Danesh M; Department of Bioinformatics, University of Würzburg, Am Hubland, 97074, BiocenterWürzburg, Germany.
Othman EM; Department of Bioinformatics, University of Würzburg, Am Hubland, 97074, BiocenterWürzburg, Germany.; Department of Biochemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt.
Dandekar T; Department of Bioinformatics, University of Würzburg, Am Hubland, 97074, BiocenterWürzburg, Germany.
Hassan HM; Department of Pharmacognosy, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt. .; Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. .
Abdelmohsen UR; Department of pharmacognosy, faculty of Pharmacy, Minia University, Minia, Egypt. .; Department of pharmacognosy, faculty of Pharmacy, Deraya University, New Minia City, 61111, Minia, Egypt. .
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Źródło:
BMC microbiology [BMC Microbiol] 2023 Dec 12; Vol. 23 (1), pp. 396. Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials*/pharmacology
Actinobacteria*/genetics
Actinobacteria*/chemistry
Callyspongia*/chemistry
Lysine-tRNA Ligase*/genetics
Animals ; Actinomyces/genetics ; Indian Ocean ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Molecular Docking Simulation ; Plasmodium falciparum
Czasopismo naukowe
Tytuł:
Targeting reversible post-translational modifications with PROTACs: a focus on enzymes modifying protein lysine and arginine residues.
Autorzy:
Pichlak M; Institute of Molecular and Industrial Biotechnology, Lodz University of Technology, Łódź, Poland.
Sobierajski T; Institute of Organic Chemistry, Lodz University of Technology, Łódź, Poland.
Błażewska KM; Institute of Organic Chemistry, Lodz University of Technology, Łódź, Poland.
Gendaszewska-Darmach E; Institute of Molecular and Industrial Biotechnology, Lodz University of Technology, Łódź, Poland.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2254012.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Lysine*
Proteolysis Targeting Chimera*
Arginine ; Ubiquitin-Protein Ligases ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł:
L-Lysine supplementation affects dietary protein quality and growth and serum amino acid concentrations in rats.
Autorzy:
Xiao CW; Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Banting Research Centre, Ottawa, ON, K1A 0K9, Canada. .; Food and Nutrition Science Program, Department of Chemistry, Carleton University, Ottawa, ON, K1S 5B6, Canada. .
Hendry A; Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Banting Research Centre, Ottawa, ON, K1A 0K9, Canada.
Kenney L; Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Banting Research Centre, Ottawa, ON, K1A 0K9, Canada.
Bertinato J; Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Banting Research Centre, Ottawa, ON, K1A 0K9, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 15; Vol. 13 (1), pp. 19943. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Lysine*/pharmacology
Tryptophan*
Male ; Animals ; Rats ; Leucine ; Caseins/pharmacology ; Histidine ; Asparagine ; Rats, Sprague-Dawley ; Dietary Supplements ; Amino Acids/pharmacology ; Diet ; Methionine ; Dietary Proteins/pharmacology ; Weight Gain ; Valine ; Racemethionine ; Carnitine ; Ornithine
Czasopismo naukowe
Tytuł:
Lysine Demethylase KDM2A Promotes Proteasomal Degradation of TCF/LEF Transcription Factors in a Neddylation-Dependent Manner.
Autorzy:
Šopin T 34wwq323; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 01 Prague, Czech Republic.
Liška F; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 01 Prague, Czech Republic.
Kučera T; Institute of Histology and Embryology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 01 Prague, Czech Republic.
Cmarko D; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 01 Prague, Czech Republic.
Vacík T; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 01 Prague, Czech Republic.
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Źródło:
Cells [Cells] 2023 Nov 13; Vol. 12 (22). Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lysine*
beta Catenin*/metabolism
Wnt Signaling Pathway ; Zinc Fingers
Czasopismo naukowe
Tytuł:
Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.
Autorzy:
Zhu J; School of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo 255000, China.
Guo W; College of Agronomy, Qingdao Agricultural University/Shandong Key Laboratory of Dryland Farming Technology/Shandong Engineering Research Center of Germplasm, Innovation and Utilization of Salt-Tolerant Crops, Qingdao 266109, China.
Lan Y; School of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo 255000, China.; National Sub-Center for International Collaboration Research on Precision Agricultural Aviation Pesticide Spraying Technology, Shandong University of Technology, Zibo 255000, China.; Academy of Ecological Unmanned Farm, Shandong University of Technology, Zibo 255000, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 11; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Lysine*/metabolism
Triticum*/metabolism
Plant Proteins/metabolism ; Seeds/metabolism ; Proteome/metabolism
Czasopismo naukowe
Tytuł:
Assessing the Role of Post-Translational Modifications of Mitochondrial RNA Polymerase.
Autorzy:
Platz KR; Department of Chemistry and Biochemistry, Hope College, Holland, MI 49423, USA.
Rudisel EJ; Department of Chemistry and Biochemistry, Hope College, Holland, MI 49423, USA.
Paluch KV; Department of Chemistry and Biochemistry, Hope College, Holland, MI 49423, USA.
Laurin TR; Department of Chemistry and Biochemistry, Hope College, Holland, MI 49423, USA.
Dittenhafer-Reed KE; Department of Chemistry and Biochemistry, Hope College, Holland, MI 49423, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 07; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article
MeSH Terms:
Lysine*/metabolism
DNA-Directed RNA Polymerases*/genetics
DNA-Directed RNA Polymerases*/metabolism
Humans ; RNA, Mitochondrial/metabolism ; HeLa Cells ; Protein Processing, Post-Translational ; DNA, Mitochondrial/genetics ; DNA, Mitochondrial/metabolism ; Threonine/metabolism ; Acetylation ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism
Czasopismo naukowe

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