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Wyświetlanie 1-20 z 9264
Tytuł:
Dictyostelium Differentiation-Inducing Factor 1 Promotes Glucose Uptake via Direct Inhibition of Mitochondrial Malate Dehydrogenase in Mouse 3T3-L1 Cells.
Autorzy:
Kubohara Y; Laboratory of Health and Life Science, Graduate School of Health and Sports Science, Juntendo University, Inzai 270-1695, Japan.
Fukunaga Y; Department of Animal Risk Management, Faculty of Risk and Crisis Management, Chiba Institute of Science, Choshi 288-0025, Japan.
Shigenaga A; Institute of Health and Sports Science & Medicine, Juntendo University, Inzai 270-1695, Japan.
Kikuchi H; Division of Natural Medicines, Faculty of Pharmacy, Keio University, Tokyo 105-8512, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 04; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 04.
Typ publikacji:
Journal Article
MeSH Terms:
Glucose*/metabolism
Malate Dehydrogenase*/antagonists & inhibitors
Malate Dehydrogenase*/metabolism
Animals ; Humans ; Mice ; 3T3-L1 Cells/drug effects ; 3T3-L1 Cells/metabolism ; Adenylate Kinase/metabolism ; Dictyostelium/metabolism ; HeLa Cells/drug effects ; HeLa Cells/metabolism ; Mammals/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Aerobic Treadmill Training on Oxidative Stress Parameters, Metabolic Enzymes, and Histomorphometric Changes in Colon of Rats with Experimentally Induced Hyperhomocysteinemia.
Autorzy:
Stojanović M; Institute of Medical Physiology 'Richard Burian', Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Todorović D; Institute of Medical Physiology 'Richard Burian', Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Gopčević K; Institute of Chemistry in Medicine 'Petar Matavulj', Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Medić A; Institute of Chemistry in Medicine 'Petar Matavulj', Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Labudović Borović M; Institute of Histology and Embryology 'Aleksandar Ð. Kostić', Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Despotović S; Institute of Histology and Embryology 'Aleksandar Ð. Kostić', Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Djuric D; Institute of Medical Physiology 'Richard Burian', Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 06; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/pharmacology
Hyperhomocysteinemia*/chemically induced
Hyperhomocysteinemia*/metabolism
Rats ; Male ; Animals ; Catalase/metabolism ; Rats, Wistar ; Malate Dehydrogenase/metabolism ; Saline Solution ; Oxidative Stress ; Superoxide Dismutase/metabolism ; Homocysteine/metabolism ; Colon/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of Dietary Supplementation with Chitosan on the Muscle Composition, Digestion, Lipid Metabolism, and Stress Resistance of Juvenile Tilapia (Oreochromis niloticus) Exposed to Cadmium-Induced Stress.
Autorzy:
Zhang, Qin (AUTHOR)
Xie, Yi (AUTHOR)
Zhang, Yuanhui (AUTHOR)
Huang, Enhao (AUTHOR)
Meng, Liuqing (AUTHOR)
Liu, Yongqiang (AUTHOR)
Tong, Tong (AUTHOR)
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Źródło:
Animals (2076-2615). Feb2024, Vol. 14 Issue 4, p541. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tat-malate dehydrogenase fusion protein protects neurons from oxidative and ischemic damage by reduction of reactive oxygen species and modulation of glutathione redox system.
Autorzy:
Kwon HJ; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea.; Department of Biomedical Sciences, and Research Institute for Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, South Korea.
Hahn KR; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Kang MS; Department of Anatomy, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, 24341, South Korea.
Choi JH; Department of Anatomy, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, 24341, South Korea.
Moon SM; Department of Neurosurgery, Kangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, 07441, South Korea.; Research Institute for Complementary & Alternative Medicine, Hallym University, Chuncheon, 24253, South Korea.
Yoon YS; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea.
Hwang IK; Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul, 08826, South Korea. .
Kim DW; Department of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, South Korea. .
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Źródło:
Scientific reports [Sci Rep] 2023 Apr 06; Vol. 13 (1), pp. 5653. Date of Electronic Publication: 2023 Apr 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Products, tat*/pharmacology
Ischemia*/drug therapy
Malate Dehydrogenase*/pharmacology
Neuroprotective Agents*/pharmacology
Oxidative Stress*/drug effects
Animals ; Gerbillinae ; Hippocampus/metabolism ; Hydrogen Peroxide/metabolism ; Neurons/metabolism ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism ; Recombinant Fusion Proteins/pharmacology ; Mice
Czasopismo naukowe
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Tytuł:
Length of course-based undergraduate research experiences (CURE) impacts student learning and attitudinal outcomes: A study of the Malate dehydrogenase CUREs Community (MCC).
Autorzy:
DeChenne-Peters SE; Department of Biology, Georgia Southern University, Savannah, Georgia, United States of America.
Rakus JF; Department of Chemistry, Marshall University, Huntington, West Virginia, United States of America.
Parente AD; Department of Chemistry and Biochemistry, Mercyhurst University, Erie, Pennsylvania, United States of America.
Mans TL; Department of Biology, North Hennepin Community College, Brooklyn Park, Minnesota, United States of America.
Eddy R; Cobblestone Evaluation and Applied Research, Inc., La Verne, California, United States of America.
Galport N; Cobblestone Evaluation and Applied Research, Inc., La Verne, California, United States of America.
Koletar C; Cobblestone Evaluation and Applied Research, Inc., La Verne, California, United States of America.
Provost JJ; Department of Chemistry and Biochemistry, University of San Diego, San Diego, California, United States of America.
Bell JE; Department of Chemistry and Biochemistry, University of San Diego, San Diego, California, United States of America.
Bell JK; Department of Chemistry and Biochemistry, University of San Diego, San Diego, California, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Mar 09; Vol. 18 (3), pp. e0282170. Date of Electronic Publication: 2023 Mar 09 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Malate Dehydrogenase*
Curriculum*
Humans ; Attitude ; Students ; Laboratories
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genome-Wide Characterization and Gene Expression Analyses of Malate Dehydrogenase ( MDH ) Genes in Low-Phosphorus Stress Tolerance of Chinese Fir ( Cunninghamia lanceolata ).
Autorzy:
Lin Y; Forestry College, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Chen W; Forestry College, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Yang Q; College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Zhang Y; Forestry College, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Ma X; Forestry College, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Fujian Provincial Colleges and University Engineering Research Center of Plantation Sustainable Management, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Li M; Forestry College, Fujian Agriculture and Forestry University, Fuzhou 350002, China.; Fujian Provincial Colleges and University Engineering Research Center of Plantation Sustainable Management, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 23; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Malate Dehydrogenase*/metabolism
Cunninghamia*/genetics
Cunninghamia*/metabolism
Malates/metabolism ; Phylogeny ; Plant Breeding ; Gene Expression Profiling ; Phosphorus/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genome-Wide Identification and Expression Analysis of Malate Dehydrogenase Gene Family in Sweet Potato and Its Two Diploid Relatives.
Autorzy:
Li Z; College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Shi L; College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Lin X; College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Tang B; College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Xing M; College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Zhu H; College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 21; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
Ipomoea batatas*/metabolism
Ipomoea*/genetics
Phylogeny ; Diploidy ; Malate Dehydrogenase/genetics ; Malate Dehydrogenase/metabolism ; Transcription Factors/metabolism ; Gene Expression Regulation, Plant
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural Comparison of hMDH2 Complexed with Natural Substrates and Cofactors: The Importance of Phosphate Binding for Active Conformation and Catalysis.
Autorzy:
Eo Y; College of Pharmacy, Dongguk University-Seoul, Goyang, Gyeonggi 10326, Korea.
Duong MTH; College of Pharmacy, Dongguk University-Seoul, Goyang, Gyeonggi 10326, Korea.
Ahn HC; College of Pharmacy, Dongguk University-Seoul, Goyang, Gyeonggi 10326, Korea.
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Źródło:
Biomolecules [Biomolecules] 2022 Aug 25; Vol. 12 (9). Date of Electronic Publication: 2022 Aug 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Malate Dehydrogenase*/chemistry
Malates*/chemistry
Binding Sites ; Catalysis ; Crystallography, X-Ray ; Glyoxylates ; Humans ; Ligands ; NAD/metabolism ; Oxaloacetic Acid/chemistry ; Oxaloacetic Acid/metabolism ; Phosphates
Czasopismo naukowe
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Tytuł:
Inhibition of Malate Dehydrogenase-2 Protects Renal Tubular Epithelial Cells from Anoxia-Reoxygenation-Induced Death or Senescence.
Autorzy:
Eleftheriadis T; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Pissas G; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Golfinopoulos S; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Efthymiadi M; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Liakopoulos V; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Stefanidis I; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
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Źródło:
Biomolecules [Biomolecules] 2022 Oct 03; Vol. 12 (10). Date of Electronic Publication: 2022 Oct 03.
Typ publikacji:
Journal Article
MeSH Terms:
Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism
Malate Dehydrogenase*/antagonists & inhibitors
Reperfusion Injury*/metabolism
Humans ; Adenosine Triphosphate/metabolism ; Apoptosis ; beta-Galactosidase/metabolism ; Epithelial Cells/metabolism ; Hypoxia/metabolism ; Interleukin-1beta/metabolism ; Ki-67 Antigen/metabolism ; Pharmaceutical Preparations/metabolism ; Reactive Oxygen Species/metabolism ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Malate synthase contributes to the survival of Salmonella Typhimurium against nutrient and oxidative stress conditions.
Autorzy:
Sarkhel R; Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Apoorva S; Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Priyadarsini S; Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Sridhar HB; Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Bhure SK; Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India.
Mahawar M; Division of Biochemistry, ICAR-Indian Veterinary Research Institute, Izatnagar, 243122, India. .
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Źródło:
Scientific reports [Sci Rep] 2022 Sep 25; Vol. 12 (1), pp. 15979. Date of Electronic Publication: 2022 Sep 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Isocitrate Lyase*/genetics
Isocitrate Lyase*/metabolism
Malate Synthase*/genetics
Malate Synthase*/metabolism
Acetates/metabolism ; Carbon/metabolism ; Carbon Dioxide ; Glucose ; Glyoxylates/metabolism ; Hypochlorous Acid ; Nutrients ; Oxidative Stress ; Salmonella typhimurium/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MDH1 and MDH2 Promote Cell Viability of Primary AT2 Cells by Increasing Glucose Uptake.
Autorzy:
Hu M; Department of Orthopedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999 Hope Road, Jiading District, Shanghai 201801, China.
Yang J; Department of Orthopedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999 Hope Road, Jiading District, Shanghai 201801, China.
Xu Y; Department of Orthopedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999 Hope Road, Jiading District, Shanghai 201801, China.
Liu J; Department of Orthopedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999 Hope Road, Jiading District, Shanghai 201801, China.
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Źródło:
Computational and mathematical methods in medicine [Comput Math Methods Med] 2022 Sep 14; Vol. 2022, pp. 2023500. Date of Electronic Publication: 2022 Sep 14 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review; Retracted Publication
MeSH Terms:
Lipopolysaccharides*
Malate Dehydrogenase*/genetics
Malate Dehydrogenase*/metabolism
Animals ; Cell Survival ; Citrates ; Glucose ; Mice ; Sincalide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Transcription Factor StuA Regulates the Glyoxylate Cycle in the Dermatophyte Trichophyton rubrum under Carbon Starvation.
Autorzy:
Petrucelli MF; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Martins-Santana L; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Sanches PR; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Oliveira VM; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Rossi A; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Martinez-Rossi NM; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 28; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Transcription Factors*
Arthrodermataceae*
Humans ; Isocitrate Lyase/genetics ; Malate Synthase/genetics ; Gluconeogenesis/genetics ; Alternative Splicing ; Carbon ; Glucose ; Keratins ; Glyoxylates
SCR Organism:
Trichophyton rubrum
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
粉尘螨线粒体样苹果酸脱氢酶基因 cDNA 克隆和分子特征分析.
Autorzy:
任雅宁
周冬梅
袁存银
廖媛芬
强士豪
罗金丹
崔玉宝
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Alternatywny tytuł:
cDNA Cloning and Molecular Characterization of Mitochondrial-like Malate Dehydrogenase Protein Gene of Dermatophagoides Farinae.
Źródło:
Progress in Modern Biomedicine. Oct2023, Vol. 23 Issue 20, p3815-3878. 6p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Integrated Metabolome and Transcriptome Analyses Reveal the Efficacy of Steroidal Saponins for Glucose and Lipid Metabolism in Hybrid Grouper (♀ Epinephelus fuscoguttatus × ♂ Epinephelus lanceolatu) Fed Higher-Lipid Diets.
Autorzy:
Deng, Hongjin (AUTHOR)
Chen, Guiqiong (AUTHOR)
Zhang, Jiacheng (AUTHOR)
Yang, Qihui (AUTHOR)
Dong, Xiaohui (AUTHOR)
Xie, Shiwei (AUTHOR)
Liang, Weixing (AUTHOR)
Tan, Beiping (AUTHOR)
Chi, Shuyan (AUTHOR)
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Źródło:
Animals (2076-2615). Sep2023, Vol. 13 Issue 18, p2894. 19p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Light-Dependent Expression and Promoter Methylation of the Genes Encoding Succinate Dehydrogenase, Fumarase, and NAD-Malate Dehydrogenase in Maize ( Zea mays L.) Leaves.
Autorzy:
Eprintsev AT; Department of Biochemistry and Cell Physiology, Voronezh State University, 394018 Voronezh, Russia.
Fedorin DN; Department of Biochemistry and Cell Physiology, Voronezh State University, 394018 Voronezh, Russia.
Igamberdiev AU; Department of Biology, Memorial University of Newfoundland, St. John's, NL A1C 5S7, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 16; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Succinate Dehydrogenase*/genetics
Succinate Dehydrogenase*/metabolism
Fumarate Hydratase*/genetics
Methylation ; Zea mays/genetics ; Zea mays/metabolism ; Malate Dehydrogenase/genetics ; Malate Dehydrogenase/metabolism ; Plant Leaves/genetics ; Plant Leaves/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural analysis and reaction mechanism of malate dehydrogenase from Geobacillus stearothermophilus.
Autorzy:
Shimozawa Y; Division of Life Science, Graduate School of Science and Engineering, Setsunan University, 17-8 Ikeda-Nakamachi, Neyagawa, Osaka 572-8508, Japan.; National Institute of Advanced Industrial Science and Technology, 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan.
Himiyama T; National Institute of Advanced Industrial Science and Technology, 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan.; DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Ikeda, Osaka 563-8577, Japan.
Nakamura T; National Institute of Advanced Industrial Science and Technology, 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan.; DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Ikeda, Osaka 563-8577, Japan.
Nishiya Y; Division of Life Science, Graduate School of Science and Engineering, Setsunan University, 17-8 Ikeda-Nakamachi, Neyagawa, Osaka 572-8508, Japan.
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Źródło:
Journal of biochemistry [J Biochem] 2021 Sep 22; Vol. 170 (1), pp. 97-105.
Typ publikacji:
Journal Article
MeSH Terms:
Geobacillus stearothermophilus/*enzymology
Malate Dehydrogenase/*metabolism
Biocatalysis ; Malate Dehydrogenase/chemistry ; Malate Dehydrogenase/isolation & purification ; Models, Molecular ; Protein Conformation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Transcriptome Analysis Reveals Genes Associated with Flooding Tolerance in Mulberry Plants.
Autorzy:
Hu, Jingtao (AUTHOR)
Duan, Yanyan (AUTHOR)
Yang, Junnian (AUTHOR)
Gan, Liping (AUTHOR)
Chen, Wenjing (AUTHOR)
Yang, Jin (AUTHOR)
Xiao, Guosheng (AUTHOR)
Guan, Lingliang (AUTHOR)
Chen, Jingsheng (AUTHOR)
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Źródło:
Life (2075-1729). May2023, Vol. 13 Issue 5, p1087. 18p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity.
Autorzy:
Reyes Romero A; Drug Design, University of Groningen, Department of Pharmacy, Groningen, The Netherlands.
Lunev S; EV Biotech, Zernikelaan 8, Groningen, the Netherlands.
Popowicz GM; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.; Department of Chemistry, Technical University of Munich, Garching, Germany.
Calderone V; CERM and Department of Chemistry, University of Florence, Sesto Fiorentino, Italy. .
Gentili M; Giotto Biotech S.r.l, Sesto F.no, Italy.
Sattler M; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.; Department of Chemistry, Technical University of Munich, Garching, Germany.
Plewka J; Faculty of Chemistry, Jagiellonian University, Krakow, Poland.
Taube M; Department of Macromolecular Physics, Faculty of Physics, Adam Mickiewicz University, Poznań, Poland.
Kozak M; Department of Macromolecular Physics, Faculty of Physics, Adam Mickiewicz University, Poznań, Poland.; National Synchrotron Radiation Centre SOLARIS, Jagiellonian University, Kraków, Poland.
Holak TA; Faculty of Chemistry, Jagiellonian University, Krakow, Poland.
Dömling ASS; Drug Design, University of Groningen, Department of Pharmacy, Groningen, The Netherlands.
Groves MR; Drug Design, University of Groningen, Department of Pharmacy, Groningen, The Netherlands. .
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Źródło:
Communications biology [Commun Biol] 2021 Aug 10; Vol. 4 (1), pp. 949. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Malate Dehydrogenase/*metabolism
Plasmodium falciparum/*metabolism
Protozoan Proteins/*metabolism
Binding Sites ; Catalytic Domain ; Malate Dehydrogenase/chemistry ; Models, Molecular ; Plasmodium falciparum/chemistry ; Protozoan Proteins/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functional partnership between carbonic anhydrase and malic enzyme in promoting gluconeogenesis in Leishmania major.
Autorzy:
Mondal DK; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, India.
Pal DS; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, India.
Abbasi M; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, India.
Datta R; Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, India.
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Źródło:
The FEBS journal [FEBS J] 2021 Jul; Vol. 288 (13), pp. 4129-4152. Date of Electronic Publication: 2021 Feb 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gluconeogenesis*
Carbonic Anhydrases/*metabolism
Leishmania major/*metabolism
Malate Dehydrogenase/*metabolism
Protozoan Proteins/*metabolism
Animals ; Carbonic Anhydrases/genetics ; Cell Line ; Glucose/metabolism ; Host-Parasite Interactions ; Leishmania major/genetics ; Leishmania major/physiology ; Macrophages/parasitology ; Malate Dehydrogenase/genetics ; Mice ; Mitochondria/enzymology ; Mitochondria/metabolism ; Oxidation-Reduction ; Protozoan Proteins/genetics ; Pyruvate Carboxylase/genetics ; Pyruvate Carboxylase/metabolism ; Pyruvic Acid/metabolism
Czasopismo naukowe
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