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Tytuł:
ApoE and apoC-III-defined HDL subtypes: a descriptive study of their lecithin cholesterol acyl transferase and cholesteryl ester transfer protein content and activity.
Autorzy:
Amaya-Montoya M; Universidad de los Andes Medical School, Carrera 7 # 116-05, Of. 413, Bogotá, Colombia.
Pinzón-Cortés JA; Universidad de los Andes Medical School, Carrera 7 # 116-05, Of. 413, Bogotá, Colombia.
Silva-Bermúdez LS; Universidad de los Andes Medical School, Carrera 7 # 116-05, Of. 413, Bogotá, Colombia.
Ruiz-Manco D; Universidad de los Andes Medical School, Carrera 7 # 116-05, Of. 413, Bogotá, Colombia.
Pérez-Matos MC; Universidad de los Andes Medical School, Carrera 7 # 116-05, Of. 413, Bogotá, Colombia.
Jiménez-Mora MA; Universidad de los Andes Medical School, Carrera 7 # 116-05, Of. 413, Bogotá, Colombia.
Mendivil CO; Universidad de los Andes Medical School, Carrera 7 # 116-05, Of. 413, Bogotá, Colombia. .; Department of Internal Medicine, Fundación Santa Fe de Bogotá, Section of Endocrinology, Carrera 7 No. 117 - 15, Bogotá, Colombia. .
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2020 May 25; Vol. 19 (1), pp. 106. Date of Electronic Publication: 2020 May 25.
Typ publikacji:
Journal Article
MeSH Terms:
Apolipoprotein C-III/*analysis
Apolipoproteins E/*analysis
Cholesterol/*metabolism
Cholesterol Ester Transfer Proteins/*analysis
Lipoproteins, HDL/*metabolism
Phosphatidylcholine-Sterol O-Acyltransferase/*analysis
Adult ; Aged ; Cholesterol Ester Transfer Proteins/blood ; Cholesterol Ester Transfer Proteins/metabolism ; Cholesterol Esters/metabolism ; Female ; Humans ; Lipoproteins, HDL/chemistry ; Lipoproteins, HDL/classification ; Male ; Middle Aged ; Phosphatidylcholine-Sterol O-Acyltransferase/blood ; Phosphatidylcholine-Sterol O-Acyltransferase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LCAT protects against Lipoprotein-X formation in a murine model of drug-induced intrahepatic cholestasis.
Autorzy:
Amar MJA; Lipoprotein Metabolism Section Translational Vascular Medicine Branch National Heart Lung and Blood Institute National Institutes of Health Bethesda MD USA.
Freeman LA; Lipoprotein Metabolism Section Translational Vascular Medicine Branch National Heart Lung and Blood Institute National Institutes of Health Bethesda MD USA.
Nishida T; Lipoprotein Metabolism Section Translational Vascular Medicine Branch National Heart Lung and Blood Institute National Institutes of Health Bethesda MD USA.
Sampson ML; Lipoprotein Metabolism Section Translational Vascular Medicine Branch National Heart Lung and Blood Institute National Institutes of Health Bethesda MD USA.
Pryor M; Lipoprotein Metabolism Section Translational Vascular Medicine Branch National Heart Lung and Blood Institute National Institutes of Health Bethesda MD USA.
Vaisman BL; Lipoprotein Metabolism Section Translational Vascular Medicine Branch National Heart Lung and Blood Institute National Institutes of Health Bethesda MD USA.
Neufeld EB; Lipoprotein Metabolism Section Translational Vascular Medicine Branch National Heart Lung and Blood Institute National Institutes of Health Bethesda MD USA.
Karathanasis SK; Lipoprotein Metabolism Section Translational Vascular Medicine Branch National Heart Lung and Blood Institute National Institutes of Health Bethesda MD USA.; Cardiovascular and Metabolic Disease Section MedImmune Gaithersburg MD USA.; NeoProgen Baltimore MD USA.
Remaley AT; Lipoprotein Metabolism Section Translational Vascular Medicine Branch National Heart Lung and Blood Institute National Institutes of Health Bethesda MD USA.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2019 Dec 29; Vol. 8 (1), pp. e00554. Date of Electronic Publication: 2019 Dec 29 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
1-Naphthylisothiocyanate/*adverse effects
Cholestasis, Intrahepatic/*drug therapy
Lipoprotein-X/*blood
Phosphatidylcholine-Sterol O-Acyltransferase/*therapeutic use
Animals ; Cholestasis, Intrahepatic/chemically induced ; Cholestasis, Intrahepatic/metabolism ; Disease Models, Animal ; Gene Knockout Techniques ; Humans ; Lipoprotein-X/drug effects ; Mice ; Mice, Transgenic ; Phosphatidylcholine-Sterol O-Acyltransferase/genetics ; Phosphatidylcholine-Sterol O-Acyltransferase/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
LCAT, ApoD, and ApoA1 Expression and Review of Cholesterol Deposition in the Cornea.
Autorzy:
Flores R; Experimental Atherosclerosis Section, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Jin X; Experimental Atherosclerosis Section, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Chang J; Experimental Atherosclerosis Section, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Zhang C; Advanced Cell Diagnostics, Newark, CA 94560, USA.
Cogan DG; Cornea and Cataract Section, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Schaefer EJ; Cardiovascular Nutrition Laboratory, Human Nutrition Research Center on Aging at Tufts University nd Tufts University School of Medicine, Boston, MA 02111, USA.; Boston Heart Diagnostics, Framingham, MA 01702, USA.
Kruth HS; Experimental Atherosclerosis Section, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
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Źródło:
Biomolecules [Biomolecules] 2019 Nov 26; Vol. 9 (12). Date of Electronic Publication: 2019 Nov 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Apolipoprotein A-I/*metabolism
Apolipoproteins D/*metabolism
Cholesterol/*metabolism
Cornea/*metabolism
Phosphatidylcholine-Sterol O-Acyltransferase/*metabolism
Aged ; Apolipoprotein A-I/blood ; Apolipoprotein A-I/genetics ; Apolipoproteins D/blood ; Apolipoproteins D/genetics ; Cornea/enzymology ; Cornea/pathology ; Cornea/ultrastructure ; Corneal Dystrophies, Hereditary/genetics ; Corneal Dystrophies, Hereditary/metabolism ; Coronary Artery Disease/genetics ; Coronary Artery Disease/metabolism ; Endothelial Cells/metabolism ; Epithelial Cells/metabolism ; Female ; Fibroblasts/metabolism ; Humans ; Keratinocytes/metabolism ; Lecithin Cholesterol Acyltransferase Deficiency/genetics ; Lecithin Cholesterol Acyltransferase Deficiency/metabolism ; Lipoproteins, HDL/blood ; Male ; Microscopy, Electron ; Middle Aged ; Phosphatidylcholine-Sterol O-Acyltransferase/blood ; Phosphatidylcholine-Sterol O-Acyltransferase/genetics ; Phospholipids/metabolism ; RNA-Seq ; Tangier Disease/genetics ; Tangier Disease/metabolism
SCR Disease Name:
Corneal Dystrophy, Crystalline, of Schnyder
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles.
Autorzy:
Manthei KA; Life Sciences Institute, University of Michigan, Ann Arbor, MI, 48109, USA.
Patra D; Departments of Biological Sciences and of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, USA.
Wilson CJ; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, 02115, USA.
Fawaz MV; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.
Piersimoni L; Departments of Biological Chemistry, Bioinformatics and Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.
Shenkar JC; Department of Pharmaceutical Science, Biointerfaces Institute, University of Michigan, Ann Arbor, MI, 48109, USA.
Yuan W; Department of Pharmaceutical Science, Biointerfaces Institute, University of Michigan, Ann Arbor, MI, 48109, USA.
Andrews PC; Departments of Biological Chemistry, Bioinformatics and Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.
Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, 02115, USA.
Schwendeman A; Department of Pharmaceutical Science, Biointerfaces Institute, University of Michigan, Ann Arbor, MI, 48109, USA.
Ohi MD; Life Sciences Institute and Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, 48109, USA.
Tesmer JJG; Departments of Biological Sciences and of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, 47907, USA. .
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Źródło:
Communications biology [Commun Biol] 2020 Jan 15; Vol. 3 (1), pp. 28. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Molecular*
Protein Conformation*
Lipoproteins, HDL/*chemistry
Multiprotein Complexes/*chemistry
Phosphatidylcholine-Sterol O-Acyltransferase/*chemistry
Binding Sites ; Catalytic Domain ; Lysine/chemistry ; Lysine/metabolism ; Mass Spectrometry ; Multiprotein Complexes/metabolism ; Multiprotein Complexes/ultrastructure ; Phosphatidylcholine-Sterol O-Acyltransferase/metabolism ; Protein Binding ; Recombinant Proteins ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification and functional analysis of missense mutations in the lecithin cholesterol acyltransferase gene in a Chilean patient with hypoalphalipoproteinemia.
Autorzy:
Tobar HE; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Cataldo LR; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
González T; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rodríguez R; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Serrano V; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Arteaga A; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Álvarez-Mercado A; INYTA, University of Granada, Granada, Spain.
Lagos CF; Facultad de Medicina y Ciencia, Universidad San Sebastián, Campus Los Leones, Santiago, Chile.
Vicuña L; Departamento de Estadísticas, Facultad de Matemáticas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Miranda JP; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pereira A; INTA, Universidad de Chile, Santiago, Chile.
Bravo C; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Aguilera CM; Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology 'José Mataix', Center of Biomedical Research, University of Granada, Granada, Spain.
Eyheramendy S; Departamento de Estadísticas, Facultad de Matemáticas, Pontificia Universidad Católica de Chile, Santiago, Chile.
Uauy R; INTA, Universidad de Chile, Santiago, Chile.; División de Pediatría, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Martínez Á; Fundación Ciencia & Vida, Santiago, Chile.
Gil Á; INYTA, University of Granada, Granada, Spain.
Francone O; Pfizer Global Research and Development, San Diego, USA.
Rigotti A; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Centro de Nutrición Molecular y Enfermedades Crónicas, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Santos JL; Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile. .
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2019 Jun 05; Vol. 18 (1), pp. 132. Date of Electronic Publication: 2019 Jun 05.
Typ publikacji:
Journal Article
MeSH Terms:
Hypoalphalipoproteinemias/*genetics
Lecithin Cholesterol Acyltransferase Deficiency/*genetics
Lipids/*blood
Phosphatidylcholine-Sterol O-Acyltransferase/*genetics
Adult ; Aged ; Chile/epidemiology ; Cholesterol/blood ; Cholesterol, HDL/blood ; Corneal Opacity/genetics ; Corneal Opacity/pathology ; Exons/genetics ; Female ; HEK293 Cells ; Humans ; Hypoalphalipoproteinemias/blood ; Hypoalphalipoproteinemias/epidemiology ; Hypoalphalipoproteinemias/pathology ; Lecithin Cholesterol Acyltransferase Deficiency/blood ; Lecithin Cholesterol Acyltransferase Deficiency/epidemiology ; Lecithin Cholesterol Acyltransferase Deficiency/pathology ; Lipoproteins, HDL/blood ; Molecular Dynamics Simulation ; Mutation, Missense/genetics ; Pedigree ; Phosphatidylcholine-Sterol O-Acyltransferase/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lipidomic Approaches to Study HDL Metabolism in Patients with Central Obesity Diagnosed with Metabolic Syndrome.
Autorzy:
Mocciaro G; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.; Department of Interdisciplinary Medicine, Clinica Medica 'C. Frugoni', Aldo Moro University of Bari, 70124 Bari, Italy.; Roger Williams Institute of Hepatology, Foundation for Liver Research, London SE5 9NT, UK.
D'Amore S; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.; Clinica Medica 'A. Murri', 'Aldo Moro' University of Bari, 70124 Bari, Italy.
Jenkins B; Welcome Trust-MRC Institute of Metabolic Science Metabolic Research Laboratories, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
Kay R; Welcome Trust-MRC Institute of Metabolic Science Metabolic Research Laboratories, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
Murgia A; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.
Herrera-Marcos LV; Department of Biochemistry and Molecular and Cellular Biology, Veterinary Faculty, University of Zaragoza, 50013 Zaragoza, Spain.
Neun S; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.
Sowton AP; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK.
Hall Z; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.; Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London SW7 2AZ, UK.
Palma-Duran SA; Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London SW7 2AZ, UK.
Palasciano G; Clinica Medica 'A. Murri', 'Aldo Moro' University of Bari, 70124 Bari, Italy.
Reimann F; Welcome Trust-MRC Institute of Metabolic Science Metabolic Research Laboratories, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
Murray A; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK.
Suppressa P; Department of Interdisciplinary Medicine, Clinica Medica 'C. Frugoni', Aldo Moro University of Bari, 70124 Bari, Italy.
Sabbà C; Department of Interdisciplinary Medicine, Clinica Medica 'C. Frugoni', Aldo Moro University of Bari, 70124 Bari, Italy.
Moschetta A; Department of Interdisciplinary Medicine, Clinica Medica 'C. Frugoni', Aldo Moro University of Bari, 70124 Bari, Italy.
Koulman A; Welcome Trust-MRC Institute of Metabolic Science Metabolic Research Laboratories, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.; Biomolecular Medicine, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London SW7 2AZ, UK.; Rowlett Institute, Foresterhill, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Vacca M; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.; Department of Interdisciplinary Medicine, Clinica Medica 'C. Frugoni', Aldo Moro University of Bari, 70124 Bari, Italy.; Roger Williams Institute of Hepatology, Foundation for Liver Research, London SE5 9NT, UK.; Welcome Trust-MRC Institute of Metabolic Science Metabolic Research Laboratories, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 17; Vol. 23 (12). Date of Electronic Publication: 2022 Jun 17.
Typ publikacji:
Journal Article
MeSH Terms:
Insulin Resistance*
Metabolic Syndrome*/complications
Metabolic Syndrome*/diagnosis
Cholesterol/metabolism ; Cholesterol, HDL ; Humans ; Lipidomics ; Lipoproteins ; Obesity/complications ; Obesity, Abdominal/complications ; Phosphatidylcholine-Sterol O-Acyltransferase/metabolism ; Phosphatidylcholines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Plasma lecithin:cholesterol acyltransferase and phospholipid transfer protein activity independently associate with nonalcoholic fatty liver disease.
Autorzy:
Nass KJ; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
van den Berg EH; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Gruppen EG; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Dullaart RPF; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
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Źródło:
European journal of clinical investigation [Eur J Clin Invest] 2018 Sep; Vol. 48 (9), pp. e12988. Date of Electronic Publication: 2018 Jul 13.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2/*metabolism
Metabolic Syndrome/*metabolism
Non-alcoholic Fatty Liver Disease/*blood
Obesity/*metabolism
Phosphatidylcholine-Sterol O-Acyltransferase/*blood
Phospholipid Transfer Proteins/*blood
Adult ; Aged ; Female ; Humans ; Insulin Resistance ; Linear Models ; Male ; Middle Aged ; Multivariate Analysis ; Non-alcoholic Fatty Liver Disease/metabolism ; Phosphatidylcholine-Sterol O-Acyltransferase/metabolism ; Phospholipid Transfer Proteins/metabolism ; Waist-Hip Ratio
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of serum cholesterol esterification rates on the development of diabetes mellitus in a general population.
Autorzy:
Tanaka SI; The Department of Internal Medicine, Toyooka Hospital Hidaka Medical Center, Toyooka, Hyogo, Japan. .
Fujioka Y; Division of Clinical Nutrition, Faculty of Nutrition, Kobe Gakuin University, Kobe, Japan.
Tsujino T; Department of Pharmacy, School of Pharmacy, Hyogo University of Health Sciences, Kobe, Japan.
Ishida T; The Division of Cardiovascular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Hirata KI; The Division of Cardiovascular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2018 Jul 28; Vol. 17 (1), pp. 180. Date of Electronic Publication: 2018 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Genetic Predisposition to Disease*
Diabetes Mellitus, Type 2/*diagnosis
Hypercholesterolemia/*diagnosis
Phosphatidylcholine-Sterol O-Acyltransferase/*blood
Adult ; Aged ; Biomarkers/blood ; Blood Glucose/metabolism ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/genetics ; Esterification ; Fatty Acids, Nonesterified/blood ; Female ; Glycated Hemoglobin/genetics ; Glycated Hemoglobin/metabolism ; Humans ; Hypercholesterolemia/blood ; Hypercholesterolemia/genetics ; Lipid Metabolism ; Male ; Middle Aged ; Odds Ratio ; Phosphatidylcholine-Sterol O-Acyltransferase/genetics ; Prognosis ; Prospective Studies ; Risk ; Sex Factors ; Triglycerides/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A simple and precise method to detect sterol esterification activity of lecithin/cholesterol acyltransferase by high-performance liquid chromatography.
Autorzy:
Wang Y; Peking University Fifth School of Clinical Medicine, Beijing Hospital, Beijing, 100730, China.; The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, China.
Wang S; The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, China.
Zhang L; The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, China.
Zeng J; Beijing Hospital and National Center for Clinical Laboratories, Beijing, 100730, China.
Yang R; The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, China.
Li H; The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, China.
Tang Y; Peking University Fifth School of Clinical Medicine, Beijing Hospital, Beijing, 100730, China.
Chen W; Beijing Hospital and National Center for Clinical Laboratories, Beijing, 100730, China.
Dong J; Peking University Fifth School of Clinical Medicine, Beijing Hospital, Beijing, 100730, China. jun_.; The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, 100730, China. jun_.
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2018 Feb; Vol. 410 (6), pp. 1785-1792. Date of Electronic Publication: 2018 Jan 06.
Typ publikacji:
Evaluation Study; Journal Article
MeSH Terms:
Chromatography, High Pressure Liquid/*methods
Enzyme Assays/*methods
Phosphatidylcholine-Sterol O-Acyltransferase/*metabolism
Sterols/*metabolism
Adult ; Aged ; Chromatography, High Pressure Liquid/economics ; Dehydrocholesterols/blood ; Dehydrocholesterols/isolation & purification ; Dehydrocholesterols/metabolism ; Enzyme Assays/economics ; Esterification ; Female ; Humans ; Male ; Middle Aged ; Phosphatidylcholine-Sterol O-Acyltransferase/blood ; Phosphatidylcholine-Sterol O-Acyltransferase/isolation & purification ; Reproducibility of Results ; Sterols/blood ; Sterols/isolation & purification ; Substrate Specificity ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative transcriptomic and lipidomic analysis of oleic environment adaptation in Saccharomyces cerevisiae: insight into metabolic reprogramming and lipid membrane expansion
Autorzy:
Shen, YiAff1, Aff2
Ke, XiaAff1, Aff2
Pan, Zi-HaoAff1, Aff2
Cao, Li-ShaAff1, Aff2
Liu, Zhi-QiangAff1, Aff2, IDs43393022000984_cor5
Zheng, Yu-GuoAff1, Aff2
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Źródło:
Systems Microbiology and Biomanufacturing. 4(1):112-126
Czasopismo naukowe
Szczegóły
Tytuł:
Apolipoprotein A1-Related Proteins and Reverse Cholesterol Transport in Antiatherosclerosis Therapy: Recent Progress and Future Perspectives.
Autorzy:
Xu X; Department of Cardiology, The First Hospital of Jilin University, Changchun, Jilin 130000, China.
Song Z; Department of Cardiology, The First Hospital of Jilin University, Changchun, Jilin 130000, China.
Mao B; Department of Cardiology, The First Hospital of Jilin University, Changchun, Jilin 130000, China.
Xu G; Department of Cardiology, The First Hospital of Jilin University, Changchun, Jilin 130000, China.
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Źródło:
Cardiovascular therapeutics [Cardiovasc Ther] 2022 Jan 10; Vol. 2022, pp. 4610834. Date of Electronic Publication: 2022 Jan 10 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review
MeSH Terms:
ATP-Binding Cassette Transporters*/metabolism
Apolipoprotein A-I*
Biological Transport ; Cholesterol ; Phosphatidylcholine-Sterol O-Acyltransferase
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins.
Autorzy:
Hommes JW; Department of Microbiology, Immunology, and Infectious Disease. Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
Kratofil RM; Department of Microbiology, Immunology, and Infectious Disease. Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada.
Wahlen S; Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Diagnostic Sciences, Laboratory of Experimental Immunology, Ghent University, Ghent, Belgium.
de Haas CJC; Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Hildebrand RB; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden, The Netherlands.
Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands.
Otto M; Pathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
van Eck M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden, The Netherlands.
Hoekstra M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden, The Netherlands.
Korporaal SJA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Gorlaeus Laboratories, Leiden, The Netherlands.; Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.
Surewaard BGJ; Department of Microbiology, Immunology, and Infectious Disease. Snyder Institute for Chronic Diseases, University of Calgary, Calgary, AB, Canada. .; Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jul 28; Vol. 11 (1), pp. 15357. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
ATP Binding Cassette Transporter 1/*genetics
Lipoproteins, HDL/*blood
Phosphatidylcholine-Sterol O-Acyltransferase/*genetics
Staphylococcal Infections/*genetics
Animals ; Bacterial Toxins/genetics ; Biofilms/drug effects ; Disease Models, Animal ; Humans ; Lipoproteins, HDL/genetics ; Mice ; Mice, Knockout ; Neutrophils/microbiology ; Staphylococcal Infections/blood ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/metabolism ; Staphylococcus aureus/pathogenicity ; Virulence Factors/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
LCAT deficiency: a systematic review with the clinical and genetic description of Mexican kindred.
Autorzy:
Mehta R; Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Av. Vasco de Quiroga 15, Belisario Domínguez Secc. 16, , Tlalpan, 14080, México City, México.
Elías-López D; Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Av. Vasco de Quiroga 15, Belisario Domínguez Secc. 16, , Tlalpan, 14080, México City, México.
Martagón AJ; Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Av. Vasco de Quiroga 15, Belisario Domínguez Secc. 16, , Tlalpan, 14080, México City, México.; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, N.L, México.
Pérez-Méndez OA; Department of Molecular Biology, Instituto Nacional de Cardiología Ignacio Chávez, México City, México.
Sánchez MLO; Department of Molecular Biology, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, México City, México.
Segura Y; Department of Molecular Biology, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, México City, México.
Tusié MT; Department of Molecular Biology, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, México City, México.
Aguilar-Salinas CA; Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Av. Vasco de Quiroga 15, Belisario Domínguez Secc. 16, , Tlalpan, 14080, México City, México. .; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, N.L, México. .
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Źródło:
Lipids in health and disease [Lipids Health Dis] 2021 Jul 13; Vol. 20 (1), pp. 70. Date of Electronic Publication: 2021 Jul 13.
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
Ethnicity/*genetics
Lecithin Cholesterol Acyltransferase Deficiency/*ethnology
Ethnicity/statistics & numerical data ; Genetic Predisposition to Disease/ethnology ; Genetic Predisposition to Disease/genetics ; Humans ; Indians, North American/genetics ; Indians, North American/statistics & numerical data ; Lecithin Cholesterol Acyltransferase Deficiency/genetics ; Mexico ; Phosphatidylcholine-Sterol O-Acyltransferase/genetics ; Racial Groups/genetics ; Racial Groups/statistics & numerical data
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Integrated analysis of methylation-driven genes and pretreatment prognostic factors in patients with hepatocellular carcinoma.
Autorzy:
He D; Department of Medical Oncology, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, 351100, China.
Liao S; Department of Medical Oncology, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, 351100, China.
Cai L; Department of Medical Oncology, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, 351100, China.
Huang W; Department of Medical Oncology, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, 351100, China.
Xie X; Department of Medical Oncology, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, 351100, China.
You M; Department of Medical Oncology, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, 351100, China. youmengxing_.
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Źródło:
BMC cancer [BMC Cancer] 2021 May 25; Vol. 21 (1), pp. 599. Date of Electronic Publication: 2021 May 25.
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Nomograms*
Biomarkers, Tumor/*genetics
Carcinoma, Hepatocellular/*genetics
Liver Neoplasms/*genetics
Carcinoma, Hepatocellular/diagnosis ; Carcinoma, Hepatocellular/mortality ; DNA Methylation ; Datasets as Topic ; Epigenesis, Genetic ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Hepatectomy ; Humans ; Kaplan-Meier Estimate ; Liver/pathology ; Liver/surgery ; Liver Neoplasms/diagnosis ; Liver Neoplasms/mortality ; Liver Neoplasms/surgery ; Neoplasm Staging ; Phosphatidylcholine-Sterol O-Acyltransferase/genetics ; Preoperative Period ; ROC Curve ; Ribosomal Protein S6 Kinases, 90-kDa/genetics ; Sequence Analysis, RNA ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 13830

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