Autor: "Park, S" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: AK-I-190, a New Catalytic Inhibitor of Topoisomerase II with Anti-Proliferative and Pro-Apoptotic Activity on Androgen-Negative Prostate Cancer Cells.
Autorzy:: Jeon KH; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Korea.
Park S; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Korea.
Jang HJ; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Korea.
Hwang SY; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Korea.
Shrestha A; College of Pharmacy, Yeungnam University, Gyeongsan 38541, Korea.
Lee ES; College of Pharmacy, Yeungnam University, Gyeongsan 38541, Korea.
Kwon Y; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Oct 18; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 18.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Cell Proliferation*
Androgens/*deficiency
DNA Topoisomerases, Type II/*chemistry
Prostatic Neoplasms, Castration-Resistant/*drug therapy
Topoisomerase II Inhibitors/*pharmacology
Cell Cycle ; Humans ; Male ; Prostatic Neoplasms, Castration-Resistant/enzymology ; Prostatic Neoplasms, Castration-Resistant/pathology ; Tumor Cells, Cultured

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Skocz do pozycji: 2.

Tytuł:: Costunolide Induces Apoptosis via the Reactive Oxygen Species and Protein Kinase B Pathway in Oral Cancer Cells.
Autorzy:: Huang H; Department of Animal Science and Biotechnology, ITRD, Kyungpook National University, Sangju 37224, Korea.
Yi JK; Gyeongbuk Livestock Research Institute, Yeongju 36052, Korea.
Lim SG; School of Life Science, Kyungpook National University, Daegu 41566, Korea.
Park S; School of Life Science, Kyungpook National University, Daegu 41566, Korea.
Zhang H; Department of Animal Science and Biotechnology, ITRD, Kyungpook National University, Sangju 37224, Korea.
Kim E; Department of Animal Science and Biotechnology, ITRD, Kyungpook National University, Sangju 37224, Korea.
Jang S; School of Life Science, Kyungpook National University, Daegu 41566, Korea.
Lee MH; College of Korean Medicine, Dongshin University, Naju 58245, Korea.
Liu K; The Pathophysiology Department, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450008, China.
Kim KR; Department of Dental Hygiene, Kyungpook National University, Sangju 37224, Korea.
Kim EK; Department of Dental Hygiene, Kyungpook National University, Sangju 37224, Korea.
Lee Y; Department of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 41566, Korea.
Kim SH; Department of Bio-Medical Analysis, Korea Polytechnic College, Chungnam 34134, Korea.
Ryoo ZY; Gyeongbuk Livestock Research Institute, Yeongju 36052, Korea.
Kim MO; Department of Animal Science and Biotechnology, ITRD, Kyungpook National University, Sangju 37224, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jul 13; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 13.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Antineoplastic Agents, Phytogenic/*pharmacology
Gene Expression Regulation, Neoplastic/*drug effects
Mouth Neoplasms/*drug therapy
Proto-Oncogene Proteins c-akt/*metabolism
Reactive Oxygen Species/*metabolism
Sesquiterpenes/*pharmacology
Animals ; Cell Cycle ; Cell Movement ; Cell Proliferation ; Humans ; Membrane Potential, Mitochondrial ; Mice ; Mice, Nude ; Mouth Neoplasms/metabolism ; Mouth Neoplasms/pathology ; Proto-Oncogene Proteins c-akt/genetics ; Signal Transduction ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 3.

Tytuł:: Developmentally regulated GTP-binding protein 2 levels in prostate cancer cell lines impact docetaxel-induced apoptosis.
Autorzy:: Kim SC; Department of Urology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Lee WH; Biomedical Research Center, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Kim SH; Biomedical Research Center, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Abdulkhayevich AA; Department of Urology, Akfa Medline, Tashkent, Uzbekistan.
Park JW; Biomedical Research Center, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Kim YM; Department of Pathology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Moon KH; Department of Urology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Lee SH; Department of Obstetrics and Gynecology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
Park S; Department of Urology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. .; Pokaż więcej
Źródło:: Investigative and clinical urology [Investig Clin Urol] 2021 Jul; Vol. 62 (4), pp. 485-495.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Docetaxel/*pharmacology
GTP-Binding Proteins/*genetics
GTP-Binding Proteins/*metabolism
Prostatic Neoplasms, Castration-Resistant/*genetics
Apoptosis/genetics ; Cell Proliferation/drug effects ; G1 Phase Cell Cycle Checkpoints/drug effects ; G1 Phase Cell Cycle Checkpoints/genetics ; G2 Phase Cell Cycle Checkpoints/drug effects ; G2 Phase Cell Cycle Checkpoints/genetics ; Gene Expression/drug effects ; Gene Knockdown Techniques ; Humans ; M Phase Cell Cycle Checkpoints/drug effects ; M Phase Cell Cycle Checkpoints/genetics ; Male ; PC-3 Cells ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; RNA, Small Interfering ; Transfection

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Skocz do pozycji: 4.

Tytuł:: 1-Cinnamoyltrichilinin from Melia azedarach Causes Apoptosis through the p38 MAPK Pathway in HL-60 Human Leukemia Cells.
Autorzy:: Jeong H; Chuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Park S; Chuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Kim SY; Chuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Cho SH; Chuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Jeong MS; Chuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Kim SR; Chuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Seo JB; Seoul Center, Korea Basic Science Institute (KBSI), Seoul 02841, Korea.
Kim SH; College of Pharmacy, Yonsei Institute of Pharmaceutical Science, Yonsei University, Incheon 21983, Korea.
Kim KN; Chuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 12; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 12.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Limonins/*pharmacology
MAP Kinase Signaling System/*drug effects
Melia azedarach/*chemistry
Plant Extracts/*pharmacology
p38 Mitogen-Activated Protein Kinases/*metabolism
Cell Survival/drug effects ; HL-60 Cells ; Humans ; Limonins/chemistry ; Molecular Structure ; Plant Extracts/chemistry

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Skocz do pozycji: 5.

Tytuł:: Anti-Cancer Effects of Lactobacillus plantarum L-14 Cell-Free Extract on Human Malignant Melanoma A375 Cells.
Autorzy:: Park J; Cellular Reprogramming and Embryo Biotechnology Laboratory, Dental Research Institute, BK21, Seoul National University School of Dentistry, Seoul 08826, Korea.
Kwon M; Cellular Reprogramming and Embryo Biotechnology Laboratory, Dental Research Institute, BK21, Seoul National University School of Dentistry, Seoul 08826, Korea.
Lee J; Biomedical Research Institute, NeoRegen Biotech Co., Ltd., Gyeonggi-do 16614, Korea.
Park S; Cellular Reprogramming and Embryo Biotechnology Laboratory, Dental Research Institute, BK21, Seoul National University School of Dentistry, Seoul 08826, Korea.; Biomedical Research Institute, NeoRegen Biotech Co., Ltd., Gyeonggi-do 16614, Korea.
Seo J; Cellular Reprogramming and Embryo Biotechnology Laboratory, Dental Research Institute, BK21, Seoul National University School of Dentistry, Seoul 08826, Korea.; Biomedical Research Institute, NeoRegen Biotech Co., Ltd., Gyeonggi-do 16614, Korea.
Roh S; Cellular Reprogramming and Embryo Biotechnology Laboratory, Dental Research Institute, BK21, Seoul National University School of Dentistry, Seoul 08826, Korea.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Aug 26; Vol. 25 (17). Date of Electronic Publication: 2020 Aug 26.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Complex Mixtures/*pharmacology
Lactobacillus plantarum/*chemistry
Melanoma/*drug therapy
Skin Neoplasms/*drug therapy
Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Complex Mixtures/chemistry ; Humans ; Melanoma/metabolism ; Melanoma/pathology ; Skin Neoplasms/metabolism ; Skin Neoplasms/pathology

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Skocz do pozycji: 6.

Tytuł:: Orientin Induces G0/G1 Cell Cycle Arrest and Mitochondria Mediated Intrinsic Apoptosis in Human Colorectal Carcinoma HT29 Cells.
Autorzy:: Thangaraj K; Department of Microbiology and Biotechnology, Bharath Institute of Higher Education and Research, Tamilnadu 600045, India.; Molecular Oncology Lab, Department of Biochemistry, Periyar University, Tamilnadu 636011, India.
Balasubramanian B; Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul 05006, Korea.
Park S; Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul 05006, Korea.
Natesan K; Molecular Oncology Lab, Department of Biochemistry, Periyar University, Tamilnadu 636011, India.; Genomic Division, National Academy of Agricultural Science, RDA, Jeollabuk 560500, Korea.
Liu W; Department of Animal Science, College of Agriculture, Guangdong Ocean University, Guangdong 524088, China.
Manju V; Molecular Oncology Lab, Department of Biochemistry, Periyar University, Tamilnadu 636011, India. .; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2019 Aug 27; Vol. 9 (9). Date of Electronic Publication: 2019 Aug 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Flavonoids/*pharmacology
G1 Phase Cell Cycle Checkpoints/*drug effects
Glucosides/*pharmacology
Mitochondria/*metabolism
Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Cytochromes c/metabolism ; DNA Damage/drug effects ; Flavonoids/chemistry ; Glucosides/chemistry ; HT29 Cells ; Humans ; Oligopeptides/metabolism ; Poly(ADP-ribose) Polymerases/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 7.

Tytuł:: Mdivi-1 Protects Adult Rat Hippocampal Neural Stem Cells against Palmitate-Induced Oxidative Stress and Apoptosis.
Autorzy:: Kim S; Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea. .
Kim C; Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea. .
Park S; Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, School of Medicine, Kyung Hee University, Seoul 02447, Korea. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2017 Sep 11; Vol. 18 (9). Date of Electronic Publication: 2017 Sep 11.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Oxidative Stress*
Adult Stem Cells/*drug effects
Neural Stem Cells/*drug effects
Neuroprotective Agents/*pharmacology
Quinazolinones/*pharmacology
Adult Stem Cells/metabolism ; Animals ; Cells, Cultured ; Dynamins/metabolism ; Hippocampus/cytology ; Membrane Potential, Mitochondrial ; Neural Stem Cells/metabolism ; Palmitates/toxicity ; Rats ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 8.

Tytuł:: Capsaicin attenuates spermatogenic cell death induced by scrotal hyperthermia through its antioxidative and anti-apoptotic activities.
Autorzy:: Park SG; College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.
Yon JM; College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.
Lin C; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, Jilin, China.
Gwon LW; College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.
Lee JG; College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.
Baek IJ; Asan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, Korea.
Lee BJ; College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.
Yun YW; College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.
Nam SY; College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.; Pokaż więcej
Źródło:: Andrologia [Andrologia] 2017 Jun; Vol. 49 (5). Date of Electronic Publication: 2016 Jul 12.
Typ publikacji:: Journal Article
MeSH Terms:: Hot Temperature*
Apoptosis/*drug effects
Capsaicin/*administration & dosage
Scrotum/*physiology
Spermatogenesis/*physiology
Animals ; Antioxidants ; Glutathione Peroxidase/analysis ; Glutathione Peroxidase/genetics ; HSP72 Heat-Shock Proteins/genetics ; Lipid Peroxidation/drug effects ; Male ; Mice ; Oxidative Stress/drug effects ; Phospholipid Hydroperoxide Glutathione Peroxidase ; RNA, Messenger/analysis ; Spermatogenesis/drug effects ; Spermatozoa/cytology ; Spermatozoa/enzymology ; Spermatozoa/physiology ; Superoxide Dismutase/genetics ; Testis/chemistry ; Testis/cytology ; Testis/physiology ; bcl-2-Associated X Protein/genetics

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Skocz do pozycji: 9.

Tytuł:: Bay 61-3606 Sensitizes TRAIL-Induced Apoptosis by Downregulating Mcl-1 in Breast Cancer Cells.
Autorzy:: Kim SY; ASAN Institute for Life Sciences, ASAN Medical Center, Seoul, Republic of Korea.
Park SE; ASAN Institute for Life Sciences, ASAN Medical Center, Seoul, Republic of Korea.
Shim SM; Department of Biomedical Sciences, Seoul National University, Seoul, Republic of Korea.
Park S; ASAN Institute for Life Sciences, ASAN Medical Center, Seoul, Republic of Korea.
Kim KK; ASAN Institute for Life Sciences, ASAN Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jeong SY; ASAN Institute for Life Sciences, ASAN Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Institute for Innovative Cancer Research, ASAN Medical Center, Seoul, Republic of Korea.
Choi EK; Department of Radiation Oncology, ASAN Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Institute for Innovative Cancer Research, ASAN Medical Center, Seoul, Republic of Korea.
Hwang JJ; ASAN Institute for Life Sciences, ASAN Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Institute for Innovative Cancer Research, ASAN Medical Center, Seoul, Republic of Korea.
Jin DH; Department of Convergence Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Institute for Innovative Cancer Research, ASAN Medical Center, Seoul, Republic of Korea.
Chung CD; ASAN Institute for Life Sciences, ASAN Medical Center, Seoul, Republic of Korea.
Kim I; ASAN Institute for Life Sciences, ASAN Medical Center, Seoul, Republic of Korea.; Department of Convergence Medicine, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Dec 31; Vol. 10 (12), pp. e0146073. Date of Electronic Publication: 2015 Dec 31 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Breast Neoplasms/*drug therapy
Breast Neoplasms/*genetics
Down-Regulation/*drug effects
Myeloid Cell Leukemia Sequence 1 Protein/*genetics
Niacinamide/*analogs & derivatives
Pyrimidines/*pharmacology
TNF-Related Apoptosis-Inducing Ligand/*genetics
Apoptosis/genetics ; Caspases/genetics ; Cell Line ; Cell Line, Tumor ; Cyclin-Dependent Kinases/genetics ; DNA Fragmentation/drug effects ; Down-Regulation/genetics ; Female ; HEK293 Cells ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; MCF-7 Cells ; Niacinamide/pharmacology ; Protein-Tyrosine Kinases/genetics ; Syk Kinase ; Transcription, Genetic/drug effects ; Transcription, Genetic/genetics

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Skocz do pozycji: 10.

Tytuł:: Cell cycle-dependent Cdc25C phosphatase determines cell survival by regulating apoptosis signal-regulating kinase 1.
Autorzy:: Cho YC; College of Pharmacy, Chung-Ang University, Seoul 156-756, Republic of Korea.
Park JE; Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea.
Park BC; Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea.
Kim JH; Targeted Gene Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-333, Republic of Korea.
Jeong DG; Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea.
Park SG; Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea.
Cho S; College of Pharmacy, Chung-Ang University, Seoul 156-756, Republic of Korea.; Pokaż więcej
Źródło:: Cell death and differentiation [Cell Death Differ] 2015 Oct; Vol. 22 (10), pp. 1605-17. Date of Electronic Publication: 2015 Jan 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*physiology
Cell Cycle/*physiology
Cell Survival/*physiology
MAP Kinase Kinase Kinase 5/*metabolism
cdc25 Phosphatases/*physiology
Animals ; Cells, Cultured ; Humans ; Mice ; Signal Transduction

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Skocz do pozycji: 11.

Tytuł:: Synergistic induction of apoptosis in high-risk DLBCL by BCL2 inhibition with ABT-199 combined with pharmacologic loss of MCL1.
Autorzy:: Li L; Bio5 Institute, University of Arizona Cancer Center, Tucson, AZ, USA.
Pongtornpipat P; Bio5 Institute, University of Arizona Cancer Center, Tucson, AZ, USA.
Tiutan T; College of Medicine, University of Arizona Cancer Center, Tucson, AZ, USA.
Kendrick SL; Department of Pathology, University of Arizona Cancer Center, Tucson, AZ, USA.
Park S; Department of Medicine, University of Arizona Cancer Center, Tucson, AZ, USA.
Persky DO; Department of Medicine, University of Arizona Cancer Center, Tucson, AZ, USA.
Rimsza LM; Department of Pathology, University of Arizona Cancer Center, Tucson, AZ, USA.
Puvvada SD; Department of Medicine, University of Arizona Cancer Center, Tucson, AZ, USA.
Schatz JH; 1] Bio5 Institute, University of Arizona Cancer Center, Tucson, AZ, USA [2] Department of Medicine, University of Arizona Cancer Center, Tucson, AZ, USA [3] Department of Pharmacology and Toxicology, University of Arizona Cancer Center, Tucson, AZ, USA.; Pokaż więcej
Źródło:: Leukemia [Leukemia] 2015 Aug; Vol. 29 (8), pp. 1702-12. Date of Electronic Publication: 2015 Apr 17.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Drug Synergism*
Apoptosis/*drug effects
Bridged Bicyclo Compounds, Heterocyclic/*pharmacology
Lymphoma, Large B-Cell, Diffuse/*pathology
Myeloid Cell Leukemia Sequence 1 Protein/*antagonists & inhibitors
Proto-Oncogene Proteins c-bcl-2/*antagonists & inhibitors
Pyridinium Compounds/*pharmacology
Sulfonamides/*pharmacology
Animals ; Antineoplastic Combined Chemotherapy Protocols ; Cell Proliferation/drug effects ; Cyclic N-Oxides ; Female ; Humans ; Immunoenzyme Techniques ; Indolizines ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Lymphoma, Large B-Cell, Diffuse/metabolism ; Lymphoma, Large B-Cell, Diffuse/mortality ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Myeloid Cell Leukemia Sequence 1 Protein/genetics ; Myeloid Cell Leukemia Sequence 1 Protein/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Messenger/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Tissue Array Analysis ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 12.

Tytuł:: GLIPR1-ΔTM synergizes with docetaxel in cell death and suppresses resistance to docetaxel in prostate cancer cells.
Autorzy:: Karanika S; Department of Genitourinary Medical Oncology - Research, Unit 18-3, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, USA. .
Karantanos T; Department of Genitourinary Medical Oncology - Research, Unit 18-3, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, USA. .
Kurosaka S; Department of Urology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan. .
Wang J; Department of Genitourinary Medical Oncology - Research, Unit 18-3, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, USA. .
Hirayama T; Department of Urology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan. .
Yang G; Department of Genitourinary Medical Oncology - Research, Unit 18-3, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, USA. .
Park S; Department of Genitourinary Medical Oncology - Research, Unit 18-3, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, USA. .
Golstov AA; Department of Thoracic & Cardio Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. .
Tanimoto R; Department of Urology, Thomas Jefferson University Hospital, Philadelphia, PA, USA. .
Li L; Department of Genitourinary Medical Oncology - Research, Unit 18-3, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, USA. .
Thompson TC; Department of Genitourinary Medical Oncology - Research, Unit 18-3, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, USA. .; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2015 Jun 19; Vol. 14, pp. 122. Date of Electronic Publication: 2015 Jun 19.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Sequence Deletion*
Apoptosis/*drug effects
Drug Resistance, Neoplasm/*drug effects
Neoplasm Proteins/*chemistry
Neoplasm Proteins/*pharmacology
Nerve Tissue Proteins/*chemistry
Nerve Tissue Proteins/*pharmacology
Prostatic Neoplasms/*pathology
Taxoids/*pharmacology
Animals ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Docetaxel ; Drug Synergism ; Enzyme Activation/drug effects ; Humans ; MAP Kinase Signaling System/drug effects ; Male ; Membrane Proteins ; Mice, Nude ; Neoplasm Metastasis ; Prostatic Neoplasms/metabolism ; Proto-Oncogene Proteins c-myc/metabolism ; Receptors, CXCR4/metabolism ; Time Factors ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 13.

Tytuł:: Apoptotic death of prostate cancer cells by a gonadotropin-releasing hormone-II antagonist.
Autorzy:: Park S; Graduate School of Medicine, Korea University, Seoul, Republic of Korea.
Han JM; Graduate School of Medicine, Korea University, Seoul, Republic of Korea.
Cheon J; Department of Urology, School of Medicine, Korea University, Seoul, Republic of Korea.
Hwang JI; Graduate School of Medicine, Korea University, Seoul, Republic of Korea.
Seong JY; Graduate School of Medicine, Korea University, Seoul, Republic of Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Jun 13; Vol. 9 (6), pp. e99723. Date of Electronic Publication: 2014 Jun 13 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antinematodal Agents/*therapeutic use
Apoptosis/*drug effects
Gonadotropin-Releasing Hormone/*analogs & derivatives
Oligopeptides/*therapeutic use
Prostatic Neoplasms/*drug therapy
Prostatic Neoplasms/*metabolism
Animals ; Cell Line, Tumor ; Cytochromes c/metabolism ; Gonadotropin-Releasing Hormone/antagonists & inhibitors ; Humans ; Lactate Dehydrogenases/metabolism ; Male ; Mice ; Mice, Nude ; Signal Transduction/drug effects

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Skocz do pozycji: 14.

Tytuł:: Extremely low frequency magnetic fields induce spermatogenic germ cell apoptosis: possible mechanism.
Autorzy:: Lee SK; Department of Urology, Sacred Heart Hospital, School of Medicine, Hallym University, 153 Kyo-dong, Gangwon, Chuncheon 200-704, Republic of Korea.
Park S; Institute of Medical Science, School of Medicine, Hallym University, Gangwon, Chuncheon 200-702, Republic of Korea.
Gimm YM; School of Electronics and Electrical Engineering, Dankook University, 152 Jukjeon-ro, Suji-gu, Gyeonggi, Yongin 448-701, Republic of Korea.
Kim YW; Institute of Medical Science, School of Medicine, Hallym University, Gangwon, Chuncheon 200-702, Republic of Korea ; Department of Microbiology, School of Medicine, Hallym University, Gangwon, Chuncheon 200-702, Republic of Korea.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2014; Vol. 2014, pp. 567183. Date of Electronic Publication: 2014 Jun 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Apoptosis/*radiation effects
Cell Differentiation/*radiation effects
Germ Cells/*radiation effects
Spermatogenesis/*radiation effects
Animals ; Cell Cycle/radiation effects ; DNA Damage/radiation effects ; Humans ; Magnetic Fields ; Male ; Reproduction/radiation effects