Temat: "Pravastatin" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Pravastatin Improves Colonic and Hepatic Microcirculatory Oxygenation during Sepsis without Affecting Mitochondrial Function and ROS Production in Rats.
Autorzy:: Kuebart A; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Gross K; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Ripkens JJ; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Tenge T; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Raupach A; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Schulz J; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Truse R; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Hof S; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Marcus C; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Vollmer C; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Bauer I; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Picker O; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.
Herminghaus A; Department of Anesthesiology, University Hospital Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 13; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 13.
Typ publikacji:: Journal Article
MeSH Terms:: Pravastatin*/pharmacology
Sepsis*/metabolism
Rats ; Animals ; Rats, Wistar ; Microcirculation ; Reactive Oxygen Species/metabolism ; Peroxisome Proliferator-Activated Receptors/metabolism ; Colon/metabolism ; Mitochondria ; Liver

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: Differential effects of metformin-mediated BSEP repression on pravastatin and bile acid pharmacokinetics in humans: A randomized controlled trial.
Autorzy:: Metry M; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Krug SA; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Karra VK; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Kane MA; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Fink JC; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Shu Y; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Wang H; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.
Polli JE; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2022 Oct; Vol. 15 (10), pp. 2468-2478. Date of Electronic Publication: 2022 Aug 07.
Typ publikacji:: Randomized Controlled Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Pravastatin*
Metformin*
Humans ; ATP Binding Cassette Transporter, Subfamily B, Member 11 ; Bile Acids and Salts ; ATP-Binding Cassette Transporters/metabolism ; Chenodeoxycholic Acid

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: Assessment of the Effect of Filgotinib on the Pharmacokinetics of Atorvastatin, Pravastatin, and Rosuvastatin in Healthy Adult Participants.
Autorzy:: Anderson K; Gilead Sciences, Inc., Foster City, California, USA.
Nelson CH; Gilead Sciences, Inc., Foster City, California, USA.
Gong Q; Gilead Sciences, Inc., Foster City, California, USA.
Alani M; Gilead Sciences, Inc., Foster City, California, USA.; Division of Rheumatology, University of Washington, Seattle, Washington, USA.
Tarnowski T; Gilead Sciences, Inc., Foster City, California, USA.
Othman AA; Gilead Sciences, Inc., Foster City, California, USA.; Pokaż więcej
Źródło:: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 Feb; Vol. 11 (2), pp. 235-245. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji:: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:: Pravastatin*/adverse effects
Pravastatin*/pharmacokinetics
Adult ; Atorvastatin/adverse effects ; Atorvastatin/pharmacokinetics ; Cross-Over Studies ; Drug Interactions ; Healthy Volunteers ; Humans ; Pyridines ; Rosuvastatin Calcium ; Triazoles

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: Effects of Mineralocorticoid Receptor Blockade and Statins on Kidney Injury Marker 1 (KIM-1) in Female Rats Receiving L-NAME and Angiotensin II.
Autorzy:: Huang J; Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Caliskan Guzelce E; Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Gholami SK; Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Gawelek KL; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.
Mitchell RN; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.
Pojoga LH; Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Romero JR; Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Williams GH; Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Adler GK; Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 30; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 30.
Typ publikacji:: Journal Article
MeSH Terms:: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology
Hypertension*/metabolism
Stroke*
Animals ; Female ; Rats ; Aldosterone/metabolism ; Angiotensin II/metabolism ; Blood Pressure ; Eplerenone/pharmacology ; Hepatitis A Virus Cellular Receptor 1/metabolism ; Kidney/metabolism ; NG-Nitroarginine Methyl Ester ; Pravastatin/pharmacology ; Rats, Wistar ; Receptors, Mineralocorticoid ; RNA, Messenger/metabolism ; Simvastatin

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: Combined Administration of Pravastatin and Metformin Attenuates Acute Radiation-Induced Intestinal Injury in Mouse and Minipig Models.
Autorzy:: Kim JM; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.; Department of Veterinary Surgery, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.
Kim H; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Oh SH; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Jang WI; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Lee SB; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Park M; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Kim S; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Park S; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Shim S; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.
Jang H; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Science, Seoul 01812, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 27; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 27.
Typ publikacji:: Journal Article
MeSH Terms:: Metformin*/pharmacology
Metformin*/therapeutic use
Diabetes Mellitus, Type 2*
Radiation Injuries*
Intestinal Diseases*
Mice ; Animals ; Swine ; Swine, Miniature ; Pravastatin/pharmacology ; Pravastatin/therapeutic use ; Intestines

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Cholesterol partially rescues the inhibition effect of pravastatin on keratinocytes proliferation by regulating cell cycle relative proteins through AKT and ERK pathway.
Autorzy:: Li M; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Jin R; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Qi Y; General Department of Hyperbaric Oxygen, Affiliated Hefei Hospital of Anhui Medical University, Hefei, Anhui, China.
Zhou H; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Zhu T; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Liu L; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Gu Y; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Luan K; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Luo X; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.
Zhang S; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.; Pokaż więcej
Źródło:: Dermatologic therapy [Dermatol Ther] 2020 Nov; Vol. 33 (6), pp. e14305. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology
Pravastatin*/pharmacology
Cell Cycle ; Cell Cycle Proteins ; Cell Proliferation ; Cholesterol ; Humans ; Keratinocytes/metabolism ; MAP Kinase Signaling System ; Proto-Oncogene Proteins c-akt/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Pravastatin Alleviates Radiation Proctitis by Regulating Thrombomodulin in Irradiated Endothelial Cells.
Autorzy:: Jang H; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kwak SY; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Park S; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.; Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kim K; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kim YH; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Na J; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kim H; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Jang WS; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Lee SJ; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Kim MJ; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Myung JK; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.; Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.
Shim S; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul 01812, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Mar 10; Vol. 21 (5). Date of Electronic Publication: 2020 Mar 10.
Typ publikacji:: Journal Article
MeSH Terms:: Endothelial Cells/*cytology
Pravastatin/*administration & dosage
Proctitis/*drug therapy
Thrombomodulin/*metabolism
Animals ; Disease Models, Animal ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Endothelial Cells/radiation effects ; Female ; Gene Expression Regulation/drug effects ; Human Umbilical Vein Endothelial Cells ; Humans ; Leukocytes/drug effects ; Leukocytes/metabolism ; Mice ; Pravastatin/pharmacology ; Proctitis/etiology ; THP-1 Cells

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Doubly robust estimator of risk in the presence of censoring dependent on time-varying covariates: application to a primary prevention trial for coronary events with pravastatin.
Autorzy:: Kawahara T; Clinical Research Promotion Center, The University of Tokyo Hospital, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. .
Shinozaki T; Department of Information and Computer Technology, Graduate School of Engineering, Tokyo University of Science, Tokyo, Japan.
Matsuyama Y; Department of Biostatistics, School of Public Health, The University of Tokyo, Tokyo, Japan.; Pokaż więcej
Źródło:: BMC medical research methodology [BMC Med Res Methodol] 2020 Jul 31; Vol. 20 (1), pp. 204. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Pravastatin*/therapeutic use
Primary Prevention*
Computer Simulation ; Humans ; Models, Statistical ; Probability ; Survival Analysis

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Statins for atherosclerotic cardiovascular disease prevention in people living with HIV in Thailand: a cost-effectiveness analysis.
Autorzy:: Boettiger DC; Kirby Institute, UNSW Sydney, Sydney, NSW, Australia.; Institute for Health Policy Studies, University of California, San Francisco, CA, USA.
Newall AT; The School of Public Health and Community Medicine, UNSW Sydney, Sydney, NSW, Australia.
Chattranukulchai P; Cardiac Center, Chulalongkorn University, Chulalongkorn Memorial Hospital, King, Bangkok, Thailand.
Chaiwarith R; Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Khusuwan S; Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand.
Avihingsanon A; The Thai Red Cross AIDS Research Centre and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Phillips A; Institute for Global Health, University College London, United Kingdom.
Bendavid E; Center for Health Policy and the Center for Primary Care and Outcomes Research, Stanford University, Stanford, CA, USA.
Law MG; Kirby Institute, UNSW Sydney, Sydney, NSW, Australia.
Kahn JG; Institute for Health Policy Studies, University of California, San Francisco, CA, USA.
Ross J; TREAT Asia/amfAR-Foundation for AIDS Research, Bangkok, Thailand.
Bautista-Arredondo S; Center for Health Systems Research, National Institute of Public Health, Cuernavaca, Mexico.
Kiertiburanakul S; Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.; Pokaż więcej
Źródło:: Journal of the International AIDS Society [J Int AIDS Soc] 2020 Jun; Vol. 23 Suppl 1, pp. e25494.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Atherosclerosis/*prevention & control
HIV Infections/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Pravastatin/*therapeutic use
Quinolines/*therapeutic use
Adult ; Atherosclerosis/complications ; Cost-Benefit Analysis ; Drug Costs ; Female ; HIV Infections/complications ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/economics ; Male ; Middle Aged ; Pravastatin/economics ; Quality-Adjusted Life Years ; Quinolines/economics ; Thailand

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Evodiamine decreased the systemic exposure of pravastatin in non-alcoholic steatohepatitis rats due to the up-regulation of hepatic OATPs.
Autorzy:: Liang R; Institute of Chinese Materia Medica, Henan Provincial Academy of Traditional Chinese Medicine, Zhengzhou, China.; School of Pharmacology, Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Ge W; Institute of Chinese Materia Medica, Henan Provincial Academy of Traditional Chinese Medicine, Zhengzhou, China.
Li B; Institute of Chinese Materia Medica, Henan Provincial Academy of Traditional Chinese Medicine, Zhengzhou, China.; School of Pharmacology, Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Cui W; Institute of Chinese Materia Medica, Henan Provincial Academy of Traditional Chinese Medicine, Zhengzhou, China.
Ma X; Institute of Chinese Materia Medica, Henan Provincial Academy of Traditional Chinese Medicine, Zhengzhou, China.
Pan Y; Institute of Chinese Materia Medica, Henan Provincial Academy of Traditional Chinese Medicine, Zhengzhou, China.
Li G; Institute of Chinese Materia Medica, Henan Provincial Academy of Traditional Chinese Medicine, Zhengzhou, China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 359-373.
Typ publikacji:: Journal Article
MeSH Terms:: Non-alcoholic Fatty Liver Disease/*drug therapy
Organic Anion Transporters/*genetics
Pravastatin/*pharmacokinetics
Quinazolines/*pharmacology
Animals ; Area Under Curve ; Herb-Drug Interactions ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacokinetics ; Male ; Rats ; Rats, Sprague-Dawley ; Up-Regulation/drug effects

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Dual-probe molecular MRI for the in vivo characterization of atherosclerosis in a mouse model: Simultaneous assessment of plaque inflammation and extracellular-matrix remodeling.
Autorzy:: Reimann C; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany. .; Department of Veterinary Medicine, Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, Königsweg 67, Building 21, 14163, Berlin, Germany. .
Brangsch J; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.; Department of Veterinary Medicine, Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, Königsweg 67, Building 21, 14163, Berlin, Germany.
Kaufmann JO; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.; Federal Institute for Materials Research and Testing (BAM), Division 1.5 Protein Analysis, Richard-Willstätter-Str. 11, 12489, Berlin, Germany.; Humboldt-Universität Berlin, Department of Chemistry, Brook-Taylor-Str. 2, 12489, Berlin, Germany.
Adams LC; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Onthank DC; Lantheus Medical Imaging, North Billerica, Massachusetts, 331 Treble Cove Road, USA.
Thöne-Reineke C; Department of Veterinary Medicine, Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin, Königsweg 67, Building 21, 14163, Berlin, Germany.
Robinson SP; Lantheus Medical Imaging, North Billerica, Massachusetts, 331 Treble Cove Road, USA.
Hamm B; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Botnar RM; King's College London, School of Biomedical Engineering and Imaging Sciences, St Thomas' Hospital Westminster Bridge Road, London, SE1 7EH, United Kingdom.; Wellcome Trust/EPSRC Centre for Medical Engineering, King's College London, London, United Kingdom.; BHF Centre of Excellence, King's College London, London, United Kingdom.; Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile.
Makowski MR; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.; King's College London, School of Biomedical Engineering and Imaging Sciences, St Thomas' Hospital Westminster Bridge Road, London, SE1 7EH, United Kingdom.; BHF Centre of Excellence, King's College London, London, United Kingdom.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Sep 25; Vol. 9 (1), pp. 13827. Date of Electronic Publication: 2019 Sep 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ferrosoferric Oxide/*administration & dosage
Gadolinium/*administration & dosage
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage
Magnetic Resonance Imaging/*methods
Plaque, Atherosclerotic/*drug therapy
Pravastatin/*administration & dosage
Animals ; Contrast Media ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Elastin/metabolism ; Feasibility Studies ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Male ; Mice ; Mice, Knockout, ApoE ; Nitric Oxide/metabolism ; Plaque, Atherosclerotic/diagnostic imaging ; Plaque, Atherosclerotic/metabolism ; Pravastatin/therapeutic use ; Sensitivity and Specificity

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Pravastatin concentrations in maternal serum, umbilical cord serum, breast milk and neonatal serum during pregnancy and lactation: A case study.
Autorzy:: Saito J; Department of Pharmacy, National Center for Child Health and Development, Tokyo, Japan.
Kaneko K; Division of Maternal Medicine, Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Abe S; Division of Maternal Medicine, Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Yakuwa N; Japan Drug Information Institute in Pregnancy, National Center for Child Health and Development, Tokyo, Japan.
Kawasaki H; Department of Pharmacy, National Center for Child Health and Development, Tokyo, Japan.
Suzuki T; Division of Obstetrics, Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Yamatani A; Department of Pharmacy, National Center for Child Health and Development, Tokyo, Japan.
Sago H; Division of Obstetrics, Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.
Murashima A; Division of Maternal Medicine, Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.; Japan Drug Information Institute in Pregnancy, National Center for Child Health and Development, Tokyo, Japan.; Pokaż więcej
Źródło:: Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2022 May; Vol. 47 (5), pp. 703-706. Date of Electronic Publication: 2021 Dec 23.
Typ publikacji:: Case Reports
MeSH Terms:: Antiphospholipid Syndrome*/drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use
Pre-Eclampsia*/drug therapy
Female ; Humans ; Infant ; Infant, Newborn ; Lactation ; Milk, Human ; Placenta ; Pravastatin/adverse effects ; Pregnancy ; Umbilical Cord

Raport

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Effect of inhalation exposure to toluene on the activity of organic anion transporting polypeptide (Oatp) using pravastatin as a probe drug in rats.
Autorzy:: Mauro M; a Departamento de Princípios Ativos Naturais e Toxicologia , Faculdade de Ciências Farmacêuticas, UNESP - Universidade Estadual Paulista , Araraquara , Brazil and.
Lepera JS; a Departamento de Princípios Ativos Naturais e Toxicologia , Faculdade de Ciências Farmacêuticas, UNESP - Universidade Estadual Paulista , Araraquara , Brazil and.
Borsari B; a Departamento de Princípios Ativos Naturais e Toxicologia , Faculdade de Ciências Farmacêuticas, UNESP - Universidade Estadual Paulista , Araraquara , Brazil and.
Capela JMV; b Departamento de Físico-Química , Instituto de Química, UNESP - Universidade Estadual Paulista , Araraquara , Brazil.
de Moraes NV; a Departamento de Princípios Ativos Naturais e Toxicologia , Faculdade de Ciências Farmacêuticas, UNESP - Universidade Estadual Paulista , Araraquara , Brazil and.; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2018 Jul; Vol. 48 (7), pp. 734-738. Date of Electronic Publication: 2017 Jul 25.
Typ publikacji:: Journal Article
MeSH Terms:: Inhalation Exposure*
Molecular Probes/*pharmacology
Organic Anion Transporters/*metabolism
Pravastatin/*pharmacology
Toluene/*toxicity
Animals ; Kinetics ; Male ; Pravastatin/blood ; Pravastatin/pharmacokinetics ; Rats, Wistar ; Time Factors

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Pravastatin Administration Alleviates Kanamycin-Induced Cochlear Injury and Hearing Loss.
Autorzy:: Lee CH; Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
Jeon J; Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
Lee SM; Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
Kim SY; Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Apr 20; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 20.
Typ publikacji:: Journal Article
MeSH Terms:: Deafness*/metabolism
Hearing Loss*/chemically induced
Hearing Loss*/drug therapy
Hearing Loss*/metabolism
Animals ; Caspase 3/metabolism ; Cochlea/metabolism ; Evoked Potentials, Auditory, Brain Stem ; Kanamycin/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Pravastatin/pharmacology ; Rats

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Association of cognitive function with increased risk of cancer death and all-cause mortality: Longitudinal analysis, systematic review, and meta-analysis of prospective observational studies.
Autorzy:: Rostamian S; Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, The Netherlands.; Department of Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom.
le Cessie S; Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands.
Marijt KA; Department of Clinical Oncology, Leiden University Medical Centre, Leiden, The Netherlands.
Jukema JW; Department of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands.
Mooijaart SP; Department of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, The Netherlands.
van Buchem MA; Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.
van Hall T; Department of Clinical Oncology, Leiden University Medical Centre, Leiden, The Netherlands.
Gussekloo J; Department of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, The Netherlands.
Trompet S; Department of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, The Netherlands.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jan 07; Vol. 17 (1), pp. e0261826. Date of Electronic Publication: 2022 Jan 07 (Print Publication: 2022).
Typ publikacji:: Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:: Cognition*
Cardiovascular Diseases/*mortality
Cognitive Dysfunction/*mortality
Neoplasms/*mortality
Aged ; Aged, 80 and over ; Cardiovascular Diseases/drug therapy ; Cognitive Dysfunction/drug therapy ; Female ; Humans ; Male ; Neoplasms/drug therapy ; Pravastatin/therapeutic use ; Prospective Studies

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Prediction of the Pharmacokinetics of Pravastatin as an OATP Substrate Using Plateable Human Hepatocytes With Human Plasma Data and PBPK Modeling.
Autorzy:: Mao J; Department of Drug Metabolism and Pharmacokinetics, Genentech, A Member of the Roche Group, South San Francisco, California, USA.
Doshi U; In Vitro ADMET Laboratories Inc. (IVAL), Columbia, Maryland, USA.
Wright M; Department of Drug Metabolism and Pharmacokinetics, Genentech, A Member of the Roche Group, South San Francisco, California, USA.
Hop CECA; Department of Drug Metabolism and Pharmacokinetics, Genentech, A Member of the Roche Group, South San Francisco, California, USA.
Li AP; In Vitro ADMET Laboratories Inc. (IVAL), Columbia, Maryland, USA.
Chen Y; Department of Drug Metabolism and Pharmacokinetics, Genentech, A Member of the Roche Group, South San Francisco, California, USA.; Pokaż więcej
Źródło:: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2018 Apr; Vol. 7 (4), pp. 251-258. Date of Electronic Publication: 2018 Feb 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Models, Biological*
Hepatocytes/*metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacokinetics
Organic Anion Transporters/*metabolism
Pravastatin/*pharmacokinetics
Adolescent ; Adult ; Cells, Cultured ; Female ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/blood ; Male ; Pravastatin/blood ; Young Adult

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: Assessing the Interactions of Statins with Human Adenylate Kinase Isoenzyme 1: Fluorescence and Enzyme Kinetic Studies.
Autorzy:: Wujak M; Faculty of Pharmacy, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Jurasza 2, 85-089 Bydgoszcz, Poland.; Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Toruń, Poland.
Kozakiewicz A; Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland.
Ciarkowska A; Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Toruń, Poland.
Loch JI; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Kraków, Poland.
Barwiolek M; Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland.
Sokolowska Z; Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland.
Budny M; Synthex Technologies Sp. z o.o., Gagarina 7/134B, 87-100 Toruń, Poland.
Wojtczak A; Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 May 24; Vol. 22 (11). Date of Electronic Publication: 2021 May 24.
Typ publikacji:: Journal Article
MeSH Terms:: Adenylate Kinase/*chemistry
Geobacillus stearothermophilus/*drug effects
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*chemistry
Adenylate Kinase/metabolism ; Amino Acid Sequence ; Atorvastatin/chemistry ; Circular Dichroism ; Fluvastatin/chemistry ; Geobacillus stearothermophilus/chemistry ; Geobacillus stearothermophilus/enzymology ; Geobacillus stearothermophilus/genetics ; Humans ; Inhibitory Concentration 50 ; Isoenzymes/chemistry ; Kinetics ; Ligands ; Molecular Docking Simulation ; Pravastatin/chemistry ; Protein Binding ; Recombinant Proteins ; Rosuvastatin Calcium/chemistry ; Sequence Alignment ; Simvastatin/chemistry ; Spectrometry, Fluorescence ; Spectrophotometry ; Static Electricity ; Temperature

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: Pravastatin attenuates the action of the ETS domain-containing protein ELK1 to prevent atherosclerosis in apolipoprotein E-knockout mice via modulation of extracellular signal-regulated kinase 1/2 signal pathway.
Autorzy:: Yan W; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Li D; Department of Medicine, Rhode Island Hospital and the Warren Alpert Medical School of Brown University, Providence, RI, USA.
Zhou X; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.; Pokaż więcej
Źródło:: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2017 Mar; Vol. 44 (3), pp. 344-352.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Atherosclerosis/*drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
MAP Kinase Signaling System/*drug effects
Oxidative Stress/*drug effects
Pravastatin/*therapeutic use
ets-Domain Protein Elk-1/*metabolism
Animals ; Apolipoproteins E/genetics ; Atherosclerosis/metabolism ; Disease Models, Animal ; Human Umbilical Vein Endothelial Cells ; Humans ; Hydrogen Peroxide/pharmacology ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Pravastatin/administration & dosage

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: Differential effects of pravastatin on the pharmacokinetics of paroxetine in normal and diabetic rats.
Autorzy:: Li F; a Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University , Nanjing , China.
Ling ZL; a Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University , Nanjing , China.
Wang ZJ; a Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University , Nanjing , China.
Zhong ZY; a Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University , Nanjing , China.
Shu N; a Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University , Nanjing , China.
Zhang M; a Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University , Nanjing , China.
Liu C; a Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University , Nanjing , China.
Liu L; a Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University , Nanjing , China.
Liu XD; a Center of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University , Nanjing , China.; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2017 Jan; Vol. 47 (1), pp. 20-30. Date of Electronic Publication: 2016 May 05.
Typ publikacji:: Journal Article
MeSH Terms:: Anticholesteremic Agents/*pharmacology
Paroxetine/*metabolism
Pravastatin/*pharmacokinetics
Selective Serotonin Reuptake Inhibitors/*pharmacokinetics
Animals ; Biological Transport ; Diabetes Mellitus, Experimental ; Hepatocytes/metabolism ; Liver/metabolism ; Pravastatin/pharmacology ; Rats

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: The effect of statins on semen parameters in patients with hypercholesterolemia: A systematic review.
Autorzy:: Anagnostis P; Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Papanikolaou D; 2nd Department of Urology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Ioannidou PG; 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Bosdou JK; 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Mikhailidis DP; Department of Clinical Biochemistry, University College London Medical School, University College London (UCL, London, UK.
Hatzimouratidis K; 2nd Department of Urology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Goulis DG; Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.; Pokaż więcej
Źródło:: Andrology [Andrology] 2021 Sep; Vol. 9 (5), pp. 1504-1511. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji:: Journal Article; Systematic Review
MeSH Terms:: Hydroxymethylglutaryl-CoA Reductase Inhibitors/*adverse effects
Hypercholesterolemia/*drug therapy
Pravastatin/*adverse effects
Semen/*drug effects
Simvastatin/*adverse effects
Adult ; Humans ; Male ; Middle Aged ; Prospective Studies ; Randomized Controlled Trials as Topic ; Sperm Motility/drug effects

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Pravastatin"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język