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    Tytuł:
    Serum Angiopoietin-2 Predicts the Occurrence and Recurrence of Hepatocellular Carcinoma after Direct-Acting Antiviral Therapy for Hepatitis C.
    Autorzy:
    Kawagishi N; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Suda G; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Yamamoto Y; Department of Gastroenterology, Hakodate Municipal Hospital, Sapporo 0608638, Japan.
    Baba M; Department of Gastroenterology and Hepatology, Japan Community Health Care Organization (JCHO) Hokkaido Hospital, Sapporo 0608638, Japan.
    Furuya K; Department of Gastroenterology and Hepatology, Japan Community Health Care Organization (JCHO) Hokkaido Hospital, Sapporo 0608638, Japan.
    Maehara O; Laboratory of Molecular and Cellular Medicine, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 0608638, Japan.
    Ohnishi S; Laboratory of Molecular and Cellular Medicine, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 0608638, Japan.
    Yoshida S; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Fu Q; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Yang Z; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Hosoda S; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Tokuchi Y; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Kitagataya T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Ohara M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Suzuki K; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Nakai M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Sho T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Natsuizaka M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Ogawa K; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
    Sakamoto N; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo 0608638, Japan.
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    Źródło:
    Viruses [Viruses] 2023 Jan 07; Vol. 15 (1). Date of Electronic Publication: 2023 Jan 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Carcinoma, Hepatocellular*/epidemiology
    Carcinoma, Hepatocellular*/etiology
    Carcinoma, Hepatocellular*/drug therapy
    Liver Neoplasms*/etiology
    Hepatitis C, Chronic*/complications
    Hepatitis C, Chronic*/drug therapy
    Hepatitis C, Chronic*/epidemiology
    Hepatitis C*/complications
    Hepatitis C*/drug therapy
    Humans ; Aged ; Antiviral Agents/therapeutic use ; Retrospective Studies ; Angiopoietin-2/therapeutic use ; Neoplasm Recurrence, Local/epidemiology ; Hepacivirus/genetics ; Risk Factors ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/complications
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Serum IL-1β predicts de novo hepatitis B virus reactivation during direct-acting antiviral therapy for hepatitis C, not during anti-cancer/immunosuppressive therapy.
    Autorzy:
    Kawagishi N; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Suda G; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan. .
    Sakamori R; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
    Matsui T; Center for Gastroenterology, Teine Keijinkai Hospital, Sapporo, Hokkaido, Japan.
    Onozawa M; Department of Hematology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Yang Z; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Yoshida S; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Ohara M; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Kimura M; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Kubo A; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Maehara O; Laboratory of Molecular and Cellular Medicine, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
    Fu Q; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Hosoda S; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Tokuchi Y; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Suzuki K; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Nakai M; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Sho T; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Morikawa K; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Natsuizaka M; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Ogawa K; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
    Sakai H; Department of Hematology, Teine Keijinkai Hospital, Sapporo, Japan.
    Ohnishi S; Laboratory of Molecular and Cellular Medicine, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
    Baba M; Department of Gastroenterology and Hepatology, Japan Community Health Care Organization Hokkaido Hospital, Hokkaido, Japan.
    Takehara T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
    Sakamoto N; Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan. sakamoto@med.hokudai.ac.jp.
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    Źródło:
    Scientific reports [Sci Rep] 2022 Oct 07; Vol. 12 (1), pp. 16800. Date of Electronic Publication: 2022 Oct 07.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Coinfection*
    Hepatitis B*/complications
    Hepatitis B*/drug therapy
    Hepatitis B*/genetics
    Hepatitis C*/complications
    Hepatitis C*/drug therapy
    Hepatitis C*/genetics
    Hepatitis C, Chronic*/drug therapy
    Antineoplastic Agents/*therapeutic use
    Interleukin-1beta/*blood
    Antiviral Agents ; Cytokines/pharmacology ; Hepacivirus/genetics ; Hepatitis B Surface Antigens ; Hepatitis B virus/genetics ; Humans ; Immunosuppression Therapy ; Interleukins/pharmacology ; Virus Activation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Baseline elevated serum angiopoietin-2 predicts long-term non-regression of liver fibrosis after direct-acting antiviral therapy for hepatitis C.
    Autorzy:
    Kawagishi N; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Suda G; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan. .
    Kimura M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Maehara O; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Yamada R; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Tokuchi Y; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Kubo A; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Kitagataya T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Shigesawa T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Suzuki K; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Ohara M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Nakai M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Sho T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Natsuizaka M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Morikawa K; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Ogawa K; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan.
    Kudo Y; Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Hokkaido, Japan.
    Nishida M; Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Hokkaido, Japan.
    Sakamoto N; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan. sakamoto@med.hokudai.ac.jp.
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    Źródło:
    Scientific reports [Sci Rep] 2021 Apr 28; Vol. 11 (1), pp. 9207. Date of Electronic Publication: 2021 Apr 28.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Angiopoietin-2/*blood
    Antiviral Agents/*therapeutic use
    Biomarkers/*blood
    Hepatitis C/*drug therapy
    Liver Cirrhosis/*diagnosis
    Adult ; Aged ; Aged, 80 and over ; Female ; Follow-Up Studies ; Hepacivirus ; Hepatitis C/virology ; Humans ; Liver Cirrhosis/blood ; Liver Cirrhosis/prevention & control ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Successful treatment by on-demand glecaprevir and pibrentasvir for hepatitis C flare during R-CHOP in patients with diffuse large B-cell lymphoma: a case report.
    Autorzy:
    Umemura M; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Suda G; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan. .; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan. .
    Tsukamoto S; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Ebata K; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Takahash S; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Sasaki T; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Nakajima S; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Hirata K; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Ozasa M; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Takano M; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Katagiri M; Sapporo Hokuyu Hospital, Sapporo, Hokkaido, Japan.
    Sakamoto N; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
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    Źródło:
    BMC infectious diseases [BMC Infect Dis] 2021 Apr 27; Vol. 21 (1), pp. 389. Date of Electronic Publication: 2021 Apr 27.
    Typ publikacji:
    Case Reports; Journal Article
    MeSH Terms:
    Aminoisobutyric Acids/*administration & dosage
    Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
    Antiviral Agents/*administration & dosage
    Benzimidazoles/*administration & dosage
    Cyclopropanes/*administration & dosage
    Hepacivirus/*genetics
    Hepatitis C/*complications
    Hepatitis C/*drug therapy
    Lactams, Macrocyclic/*administration & dosage
    Leucine/*analogs & derivatives
    Lymphoma, Large B-Cell, Diffuse/*complications
    Lymphoma, Large B-Cell, Diffuse/*drug therapy
    Proline/*analogs & derivatives
    Quinoxalines/*administration & dosage
    Sulfonamides/*administration & dosage
    Cyclophosphamide/therapeutic use ; Doxorubicin/therapeutic use ; Genotype ; Humans ; Leucine/administration & dosage ; Male ; Middle Aged ; Prednisone/therapeutic use ; Proline/administration & dosage ; Pyrrolidines ; RNA, Viral/blood ; RNA, Viral/genetics ; Rituximab/therapeutic use ; Sustained Virologic Response ; Vincristine/therapeutic use ; Viral Load/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Interferon (IFN) and Cellular Immune Response Evoked in RNA-Pattern Sensing During Infection with Hepatitis C Virus (HCV).
    Autorzy:
    Nakai M; Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan. .; Department of Gastroenterology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan. .
    Oshiumi H; Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan. .
    Funami K; Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan. .
    Okamoto M; Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan. .
    Matsumoto M; Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan. .
    Seya T; Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan. .
    Sakamoto N; Department of Gastroenterology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan. sakamoto@med.hokudai.ac.jp.
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    Źródło:
    Sensors (Basel, Switzerland) [Sensors (Basel)] 2015 Oct 23; Vol. 15 (10), pp. 27160-73. Date of Electronic Publication: 2015 Oct 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Review
    MeSH Terms:
    Hepatitis C/*immunology
    Immunity, Cellular/*immunology
    Interferons/*metabolism
    Killer Cells, Natural/*immunology
    Humans ; Immunity, Cellular/genetics ; Interferons/genetics ; Toll-Like Receptor 3
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Inhibition of intracellular hepatitis C virus replication by nelfinavir and synergistic effect with interferon-α.
    Autorzy:
    Toma, S.
    Yamashiro, T.
    Arakaki, S.
    Shiroma, J.
    Maeshiro, T.
    Hibiya, K.
    Sakamoto, N.
    Kinjo, F.
    Tateyama, M.
    Fujita, J.
    Pokaż więcej
    Temat:
    HEPATITIS C virus
    HIV-positive persons
    LIVER diseases
    HEPATITIS C
    HIV
    Źródło:
    Journal of Viral Hepatitis; Jul2009, Vol. 16 Issue 7, p506-512, 7p, 3 Graphs
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin.
    Autorzy:
    Itakura, J.
    Nagayama, K.
    Enomoto, N.
    Hamano, K.
    Sakamoto, N.
    Fanning, L. J.
    Kenny-Walsh, E.
    Shanahan, F.
    Watanabe, M.
    Pokaż więcej
    Temat:
    HEPATITIS C virus
    FLAVIVIRUSES
    HEPATITIS viruses
    HEPATITIS C
    IMMUNOGLOBULINS
    VIRAL load
    GENOMES
    Źródło:
    Journal of Viral Hepatitis; Nov2005, Vol. 12 Issue 6, p594-603, 10p
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Characteristic sequence changes of hepatitis C virus genotype 2b associated with sustained biochemical response to IFN therapy.
    Autorzy:
    Tanabe, Y.
    Nagayama, K.
    Enomoto, N.
    Izumi, N.
    Tazawa, J.
    Kurosaki, M.
    Sakamoto, N.
    Sato, C.
    Watanabe, M.
    Pokaż więcej
    Temat:
    HEPATITIS C virus
    INTERFERONS
    HEPATITIS C
    ANTIVIRAL agents
    VIRAL hepatitis
    LIVER diseases
    IMMUNOTHERAPY
    GASTROENTEROLOGY
    Źródło:
    Journal of Viral Hepatitis; May2005, Vol. 12 Issue 3, p251-261, 11p
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Introduction of NS5A mutations enables subgenomic HCV replicon derived from chimpanzee-infectious HC-J4 isolate to replicate efficiently in Huh-7 cells.
    Autorzy:
    Maekawa, S.
    Enomoto, N.
    Sakamoto, N.
    Kurosaki, M.
    Ueda, E.
    Kohashi, T.
    Watanabe, H.
    Chen, C.-H.
    Yamashiro, T.
    Tanabe, Y.
    Kanazawa, N.
    Sato, C.
    Watanabe, M.
    Pokaż więcej
    Temat:
    HEPATITIS C
    HEPATITIS C virus
    VIRAL hepatitis
    GENETIC transformation
    ANTIBACTERIAL agents
    NUCLEIC acids
    Źródło:
    Journal of Viral Hepatitis; Sep2004, Vol. 11 Issue 5, p394-403, 10p
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-10 z 10

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