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    Wyświetlanie 1-4 z 4
    Tytuł:
    Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate.
    Autorzy:
    Garg S; Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
    Garg TK; UAMS Myeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
    Wise SY; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
    Fatanmi OO; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
    Miousse IR; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
    Savenka AV; Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
    Basnakian AG; Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.; John L. McClellan Memorial VA Hospital, Central Arkansas Veterans Healthcare System, Little Rock, AR 72205, USA.
    Singh VK; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
    Hauer-Jensen M; Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2022 Apr 22; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 22.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Acute Radiation Syndrome*/drug therapy
    Acute Radiation Syndrome*/prevention & control
    Chromans*/therapeutic use
    Radiation-Protective Agents*/pharmacology
    Radiation-Protective Agents*/therapeutic use
    Vitamin E*/analogs & derivatives
    Vitamin E*/therapeutic use
    Animals ; Disease Models, Animal ; Intestines/pathology ; Intestines/radiation effects ; Ki-67 Antigen ; Macaca mulatta
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    TUNEL Assay: A Powerful Tool for Kidney Injury Evaluation.
    Autorzy:
    Moore CL; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.
    Savenka AV; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.
    Basnakian AG; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.; John L. McClellan Memorial VA Hospital, Central Arkansas Veterans Healthcare System, 4300 West 7th Street, Little Rock, AR 72205, USA.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2021 Jan 02; Vol. 22 (1). Date of Electronic Publication: 2021 Jan 02.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    DNA Fragmentation*
    Apoptosis/*genetics
    In Situ Nick-End Labeling/*methods
    Kidney Diseases/*diagnosis
    Animals ; Cells, Cultured ; Deoxyribonucleases/metabolism ; Endonucleases/metabolism ; Humans ; Kidney/cytology ; Kidney/enzymology ; Kidney/injuries ; Kidney/pathology ; Kidney Diseases/enzymology ; Kidney Diseases/physiopathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    DNase I Induces Other Endonucleases in Kidney Tubular Epithelial Cells by Its DNA-Degrading Activity.
    Autorzy:
    Fahmi T; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.
    Wang X; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.
    Zhdanov DD; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.
    Islam I; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.
    Apostolov EO; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.
    Savenka AV; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.
    Basnakian AG; Department of Pharmacology & Toxicology, University of Arkansas for Medical Sciences, 4301 West Markham Street, #638, Little Rock, AR 72205, USA.; Central Arkansas Veterans Healthcare System, 4300 West 7th Street, Little Rock, AR 72205, USA.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2020 Nov 17; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 17.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    DNA Breaks*
    DNA Fragmentation*
    DNA/*metabolism
    Deoxyribonuclease I/*metabolism
    Epithelial Cells/*enzymology
    Kidney Tubules/*enzymology
    Animals ; Cell Line ; DNA/genetics ; Deoxyribonuclease I/genetics ; Rats
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Fractionated radiation suppresses Kruppel-like factor 2 pathway to a greater extent than by single exposure to the same total dose.
    Autorzy:
    Sadhukhan R; Division of Radiation Health, Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
    Leung JWC; Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
    Garg S; Division of Radiation Health, Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
    Krager KJ; Division of Radiation Health, Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
    Savenka AV; Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
    Basnakian AG; Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Central Arkansas Veterans Healthcare System, Little Rock, AR, USA.
    Pathak R; Division of Radiation Health, Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, USA. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 May 07; Vol. 10 (1), pp. 7734. Date of Electronic Publication: 2020 May 07.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Human Umbilical Vein Endothelial Cells/*radiation effects
    Kruppel-Like Transcription Factors/*genetics
    Nitric Oxide Synthase Type III/*genetics
    Thrombomodulin/*genetics
    Dose Fractionation, Radiation ; Dose-Response Relationship, Radiation ; Gene Expression Regulation/radiation effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Intercellular Adhesion Molecule-1/genetics ; MEF2 Transcription Factors/genetics ; Mitogen-Activated Protein Kinase 7/genetics ; Neoplasms/genetics ; Neoplasms/pathology ; Neoplasms/radiotherapy ; Radiation ; Signal Transduction/radiation effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-4 z 4

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