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Tytuł:
Determinants of epidermal nerve fibre density in antiretroviral-naïve HIV-infected individuals.
Autorzy:
Shikuma, Cm
Gerschenson, M
Ananworanich, J
Valcour, Vg
Teeratakulpisarn, N
Jadwattanakul, T
Degruttola, V
Liang, C-Y
Mcarthur, Jc
Ebenezer, Gj
Chomchey, N
Praihirunkit, P
Hongchookiath, P
Mathajittiphun, P
Nakamoto, B
Hauer, P
Phanuphak, P
Phanuphak, N
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Źródło:
HIV Medicine. Nov2012, Vol. 13 Issue 10, p602-608. 7p. 1 Black and White Photograph, 3 Charts, 1 Graph.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV.
Autorzy:
Corley MJ; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York City, New York, USA.
Pang APS; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York City, New York, USA.
Shikuma CM; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
Ndhlovu LC; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York City, New York, USA.
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Źródło:
Aging cell [Aging Cell] 2024 Jan; Vol. 23 (1), pp. e13926. Date of Electronic Publication: 2023 Sep 07.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Metformin*/pharmacology
Metformin*/therapeutic use
HIV Infections*/drug therapy
HIV Infections*/genetics
Humans ; Aged ; Monocytes ; CD8-Positive T-Lymphocytes ; Retrospective Studies ; Biomarkers ; Epigenesis, Genetic ; DNA Methylation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Platelet and HIV Interactions and Their Contribution to Non-AIDS Comorbidities.
Autorzy:
Awamura T; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Nakasone ES; University of Hawai'i Cancer Center, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.; Department of Medicine, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Gangcuangco LM; Hawai'i Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Subia NT; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Bali AJ; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Chow DC; Department of Medicine, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.; Hawai'i Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Shikuma CM; Hawai'i Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
Park J; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.; Hawai'i Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI 96813, USA.
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Źródło:
Biomolecules [Biomolecules] 2023 Nov 02; Vol. 13 (11). Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
HIV Infections*
Humans ; Inflammation/metabolism ; Blood Platelets/metabolism ; Hemostasis ; Leukocytes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Low-density granulocytes display immature cells with enhanced NET formation in people living with HIV.
Autorzy:
Park J; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA. .; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA. .
Dean LS; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.
Heckl J; Department of Cell and Molecular Biology, John A. Burns School Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.
Gangcuangco LM; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.; Department of Medicine, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.
Pedro TK; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.
Tallquist MD; Center for Cardiovascular Research, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, 96813, USA.
Seto TB; The Queen's Medical Center, Honolulu, HI, 96813, USA.; Department of Medicine, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.
Shiramizu B; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.
Chow DC; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.; Department of Medicine, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.
Shikuma CM; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.; Department of Medicine, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI, 96813, USA.
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 16; Vol. 13 (1), pp. 13282. Date of Electronic Publication: 2023 Aug 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Granulocytes*
HIV Infections*
Humans ; Histones ; Neutrophils ; Aging
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dynamic SARS-CoV-2 emergence algorithm for rationally-designed logical next-generation vaccines.
Autorzy:
Maison DP; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, University of Hawai'i at Mānoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases Research, University of Hawai'i at Mānoa, Honolulu, HI, USA.; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Ching LL; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, University of Hawai'i at Mānoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases Research, University of Hawai'i at Mānoa, Honolulu, HI, USA.; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Cleveland SB; Hawaii Data Science Institute, University of Hawai'i at Mānoa, Honolulu, HI, USA.; Department of Cyberinfrastructure, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Tseng AC; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, University of Hawai'i at Mānoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases Research, University of Hawai'i at Mānoa, Honolulu, HI, USA.; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Nakano E; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, University of Hawai'i at Mānoa, Honolulu, HI, USA.; Pacific Center for Emerging Infectious Diseases Research, University of Hawai'i at Mānoa, Honolulu, HI, USA.; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Shikuma CM; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, University of Hawai'i at Mānoa, Honolulu, HI, USA.; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA.; Hawaii Center for AIDS, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Nerurkar VR; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, University of Hawai'i at Mānoa, Honolulu, HI, USA. .; Pacific Center for Emerging Infectious Diseases Research, University of Hawai'i at Mānoa, Honolulu, HI, USA. .; John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA. .
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Źródło:
Communications biology [Commun Biol] 2022 Oct 10; Vol. 5 (1), pp. 1081. Date of Electronic Publication: 2022 Oct 10.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
COVID-19*/epidemiology
COVID-19*/prevention & control
COVID-19 Vaccines*
SARS-CoV-2*/genetics
Algorithms ; Antibodies, Monoclonal ; Epitopes ; Humans ; Membrane Glycoproteins/metabolism ; Spike Glycoprotein, Coronavirus/genetics ; Viral Envelope Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hiding in plain sight - platelets, the silent carriers of HIV-1.
Autorzy:
Baumer Y; Department of Tropical Medicine, John A. Burns School of Medicine, Honolulu, HI, USA.; Center for Cardiovascular Research, John A.Burns School of Medicine,Honolulu,HI,USA.; Social Determinants of Obesity and Cardiovascular Risk Laboratory, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Weatherby TM; Pacific Biosciences Research Center, Biological Electron Microscope Facility, University of Hawaii, Honolulu, HI, USA.
Mitchell BI; Department of Tropical Medicine, John A. Burns School of Medicine, Honolulu, HI, USA.
SahBandar IN; Department of Tropical Medicine, John A. Burns School of Medicine, Honolulu, HI, USA.; Hawaii Center for AIDS, John A. Burns School of Medicine, Honolulu, HI, USA.
Premeaux TA; Department of Tropical Medicine, John A. Burns School of Medicine, Honolulu, HI, USA.
Michelle L D; Department of Tropical Medicine, John A. Burns School of Medicine, Honolulu, HI, USA.; Gilead Sciences Inc, Foster City, CA, USA.
Gutierrez-Huerta CA; Social Determinants of Obesity and Cardiovascular Risk Laboratory, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Powell-Wiley TM; Social Determinants of Obesity and Cardiovascular Risk Laboratory, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Brown TR; Palm Springs, CA, USA.
Boisvert WA; Center for Cardiovascular Research, John A.Burns School of Medicine,Honolulu,HI,USA.
Shikuma CM; Hawaii Center for AIDS, John A. Burns School of Medicine, Honolulu, HI, USA.
Ndhlovu LC; Department of Tropical Medicine, John A. Burns School of Medicine, Honolulu, HI, USA.; Hawaii Center for AIDS, John A. Burns School of Medicine, Honolulu, HI, USA.
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Źródło:
Platelets [Platelets] 2021 Nov 17; Vol. 32 (8), pp. 1038-1042. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelets/*metabolism
HIV Infections/*blood
HIV-1/*pathogenicity
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Correction: Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation.
Autorzy:
Gangcuangco LMA
Mitchell BI
Siriwardhana C
Kohorn LB
Chew GM
Bowler S
Kallianpur KJ
Chow DC
Ndhlovu LC
Gerschenson M
Shikuma CM
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Źródło:
PloS one [PLoS One] 2021 Mar 25; Vol. 16 (3), pp. e0249428. Date of Electronic Publication: 2021 Mar 25 (Print Publication: 2021).
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Increased Monocyte Inflammatory Responses to Oxidized LDL Are Associated with Insulin Resistance in HIV-Infected Individuals on Suppressive Antiretroviral Therapy.
Autorzy:
Mitchell BI; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Laws EI; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Chow DC; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
SahBandar IN; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Gangcuangco LMA; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Shikuma CM; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
Ndhlovu LC; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.
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Źródło:
Viruses [Viruses] 2020 Oct 05; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Insulin Resistance*
HIV Infections/*complications
Lipoproteins, LDL/*metabolism
Monocytes/*metabolism
Antirheumatic Agents/therapeutic use ; Blood Glucose ; Cardiometabolic Risk Factors ; Cytokines/metabolism ; Fasting ; Female ; HIV Infections/drug therapy ; Humans ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Interleukin-8/metabolism ; Leukocytes, Mononuclear ; Male ; Middle Aged ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation.
Autorzy:
Gangcuangco LMA; University of Hawaii, Honolulu, Hawaii, United States of America.
Mitchell BI; University of Hawaii, Honolulu, Hawaii, United States of America.
Siriwardhana C; University of Hawaii, Honolulu, Hawaii, United States of America.
Kohorn LB; University of Hawaii, Honolulu, Hawaii, United States of America.
Chew GM; University of Hawaii, Honolulu, Hawaii, United States of America.
Bowler S; University of Hawaii, Honolulu, Hawaii, United States of America.
Kallianpur KJ; University of Hawaii, Honolulu, Hawaii, United States of America.
Chow DC; University of Hawaii, Honolulu, Hawaii, United States of America.
Ndhlovu LC; University of Hawaii, Honolulu, Hawaii, United States of America.
Gerschenson M; University of Hawaii, Honolulu, Hawaii, United States of America.
Shikuma CM; University of Hawaii, Honolulu, Hawaii, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Apr 30; Vol. 15 (4), pp. e0231761. Date of Electronic Publication: 2020 Apr 30 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Oxidative Phosphorylation*
Anti-HIV Agents/*therapeutic use
HIV Infections/*immunology
HIV-1/*immunology
Leukocytes, Mononuclear/*immunology
Mitochondria/*metabolism
CD4-CD8 Ratio ; Cross-Sectional Studies ; Female ; HIV Infections/diagnosis ; HIV Infections/drug therapy ; HIV Infections/virology ; HIV-1/genetics ; HIV-1/isolation & purification ; Hawaii ; Host-Pathogen Interactions/immunology ; Humans ; Leukocytes, Mononuclear/cytology ; Lymphocyte Activation ; Male ; Middle Aged ; Mitochondria/immunology ; RNA, Viral/isolation & purification ; Severity of Illness Index
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative DNA methylomic analyses reveal potential origins of novel epigenetic biomarkers of insulin resistance in monocytes from virally suppressed HIV-infected adults.
Autorzy:
Dye CK; Department of Native Hawaiian Health, University of Hawaii John A. Burns School of Medicine, 677 Ala Moana Blvd, Suite 1016B, University of Hawaii, Honolulu, HI, 96813, USA.; Department of Molecular Bioscience and Bioengineering, University of Hawaii, 1955 East-West Road, Ag. Science 208, Honolulu, HI, 96822, USA.
Corley MJ; Department of Native Hawaiian Health, University of Hawaii John A. Burns School of Medicine, 677 Ala Moana Blvd, Suite 1016B, University of Hawaii, Honolulu, HI, 96813, USA.
Li D; School of Medicine and Dentistry, University of Rochester Medical Center, 601 Elmwood Ave., CU430708, Rochester, NY, 14642, USA.
Khadka VS; Office of Biostatistics & Quantitative Health Sciences, University of Hawaii John A. Burns School of Medicine, 651 Ilalo Street, Medical Education Building, Suite 411, Honolulu, HI, 96813, USA.
Mitchell BI; Department of Tropical Medicine, University of Hawaii, 651 Illalo Street, BSB 325C, Honolulu, HI, 96815, USA.
Sultana R; Department of Native Hawaiian Health, University of Hawaii John A. Burns School of Medicine, 677 Ala Moana Blvd, Suite 1016B, University of Hawaii, Honolulu, HI, 96813, USA.
Lum-Jones A; Department of Native Hawaiian Health, University of Hawaii John A. Burns School of Medicine, 677 Ala Moana Blvd, Suite 1016B, University of Hawaii, Honolulu, HI, 96813, USA.
Shikuma CM; Hawaii Center for AIDS, University of Hawaii, 651 Ilalo St. BSB 231, Honolulu, HI, 96813, USA.
Ndhlovu LC; Department of Tropical Medicine, University of Hawaii, 651 Illalo Street, BSB 325C, Honolulu, HI, 96815, USA.
Maunakea AK; Department of Native Hawaiian Health, University of Hawaii John A. Burns School of Medicine, 677 Ala Moana Blvd, Suite 1016B, University of Hawaii, Honolulu, HI, 96813, USA. .
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Źródło:
Clinical epigenetics [Clin Epigenetics] 2019 Jun 28; Vol. 11 (1), pp. 95. Date of Electronic Publication: 2019 Jun 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Methylation*
Genetic Markers*
Insulin Resistance*
Epigenomics/*methods
HIV Infections/*virology
Case-Control Studies ; CpG Islands ; Female ; Gene Regulatory Networks ; HIV Infections/genetics ; Humans ; Logistic Models ; Male ; Middle Aged ; Monocytes/chemistry ; Polymorphism, Single Nucleotide ; Prospective Studies ; Whole Genome Sequencing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment.
Autorzy:
Corley MJ; Department of Native Hawaiian Health, John A. Burns School of Medicine, Suite 1016B, University of Hawaii, Honolulu, HI 96813, USA.
Dye C; Department of Native Hawaiian Health, John A. Burns School of Medicine, Suite 1016B, University of Hawaii, Honolulu, HI 96813, USA.
D'Antoni ML; Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, 651 Ilalo Street, BSB325C, Honolulu, HI 96813, USA.
Byron MM; Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, 651 Ilalo Street, BSB325C, Honolulu, HI 96813, USA.
Yo KL; Department of Native Hawaiian Health, John A. Burns School of Medicine, Suite 1016B, University of Hawaii, Honolulu, HI 96813, USA.
Lum-Jones A; Department of Native Hawaiian Health, John A. Burns School of Medicine, Suite 1016B, University of Hawaii, Honolulu, HI 96813, USA.
Nakamoto B; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, 651 Ilalo Street, BSB, Honolulu, HI 96815, USA.
Valcour V; Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA.
SahBandar I; Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, 651 Ilalo Street, BSB325C, Honolulu, HI 96813, USA.
Shikuma CM; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, 651 Ilalo Street, BSB, Honolulu, HI 96815, USA.
Ndhlovu LC; Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, 651 Ilalo Street, BSB325C, Honolulu, HI 96813, USA.; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, 651 Ilalo Street, BSB, Honolulu, HI 96815, USA.
Maunakea AK; Department of Native Hawaiian Health, John A. Burns School of Medicine, Suite 1016B, University of Hawaii, Honolulu, HI 96813, USA.
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Źródło:
Scientific reports [Sci Rep] 2016 Sep 15; Vol. 6, pp. 33310. Date of Electronic Publication: 2016 Sep 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Central Nervous System/*metabolism
Cognitive Dysfunction/*genetics
DNA Methylation/*genetics
HIV Infections/*genetics
Aged ; Central Nervous System/immunology ; Central Nervous System/pathology ; Central Nervous System/virology ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/immunology ; Cognitive Dysfunction/pathology ; Female ; Gene Expression Regulation/genetics ; HIV/genetics ; HIV/pathogenicity ; HIV Infections/complications ; HIV Infections/immunology ; HIV Infections/pathology ; Humans ; Male ; Middle Aged ; Monocytes/immunology ; Monocytes/pathology ; Transcriptome/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.
Autorzy:
Abdel-Mohsen M; Blood Systems Research Institute, San Francisco, California, United States of America.; University of California, San Francisco, California, United States of America.
Chavez L; Blood Systems Research Institute, San Francisco, California, United States of America.
Tandon R; School of Biotechnology, Jawaharlal Nehru University, New Delhi, India.
Chew GM; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Deng X; Blood Systems Research Institute, San Francisco, California, United States of America.
Danesh A; Blood Systems Research Institute, San Francisco, California, United States of America.; University of California, San Francisco, California, United States of America.
Keating S; Blood Systems Research Institute, San Francisco, California, United States of America.
Lanteri M; Blood Systems Research Institute, San Francisco, California, United States of America.
Samuels ML; RainDance Technologies, Inc., Billerica, Massachusetts, United States of America.
Hoh R; University of California, San Francisco, California, United States of America.
Sacha JB; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.
Norris PJ; Blood Systems Research Institute, San Francisco, California, United States of America.; University of California, San Francisco, California, United States of America.
Niki T; GalPharma Co., Ltd., Takamatsu-shi, Kagawa, Japan.; Department of Immunology and Immunopathology, Kagawa University, Kagawa, Japan.
Shikuma CM; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Hirashima M; GalPharma Co., Ltd., Takamatsu-shi, Kagawa, Japan.; Department of Immunology and Immunopathology, Kagawa University, Kagawa, Japan.
Deeks SG; University of California, San Francisco, California, United States of America.
Ndhlovu LC; Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Pillai SK; Blood Systems Research Institute, San Francisco, California, United States of America.; University of California, San Francisco, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2016 Jun 02; Vol. 12 (6), pp. e1005677. Date of Electronic Publication: 2016 Jun 02 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
CD4-Positive T-Lymphocytes/*virology
Galectins/*metabolism
HIV Infections/*metabolism
Virus Activation/*physiology
Virus Latency/*physiology
Anti-HIV Agents/therapeutic use ; Blotting, Western ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Gene Expression Profiling ; HIV Infections/drug therapy ; HIV Infections/virology ; HIV-1/physiology ; Humans ; Polymerase Chain Reaction ; Transcription, Genetic/physiology ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Elevation of Non-Classical (CD14+/lowCD16++) Monocytes Is Associated with Increased Albuminuria and Urine TGF-β1 in HIV-Infected Individuals on Stable Antiretroviral Therapy.
Autorzy:
Mitchell BI; Department of Tropical Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
Byron MM; Department of Tropical Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Ng RC; Department of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Chow DC; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.; Department of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Ndhlovu LC; Department of Tropical Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
Shikuma CM; Department of Tropical Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.; Department of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
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Źródło:
PloS one [PLoS One] 2016 Apr 20; Vol. 11 (4), pp. e0153758. Date of Electronic Publication: 2016 Apr 20 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Albuminuria/*complications
Anti-HIV Agents/*therapeutic use
HIV Infections/*drug therapy
HIV Infections/*urine
Monocytes/*metabolism
Transforming Growth Factor beta1/*urine
Aged ; Biomarkers/urine ; Chronic Disease ; Cross-Sectional Studies ; Female ; Fibrosis ; HIV Infections/complications ; HIV Infections/immunology ; Humans ; Lipopolysaccharide Receptors/metabolism ; Male ; Middle Aged ; Receptors, IgG/metabolism ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Non-Classical Monocytes and Monocyte Chemoattractant Protein-1 (MCP-1) Correlate with Coronary Artery Calcium Progression in Chronically HIV-1 Infected Adults on Stable Antiretroviral Therapy.
Autorzy:
Zungsontiporn N; Hawaii Center for AIDS, Department of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.
Tello RR; Hawaii Center for AIDS, Department of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.
Zhang G; Department of Tropical Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.
Mitchell BI; Hawaii Center for AIDS, Department of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.; Department of Tropical Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.
Budoff M; Los Angeles Biomedical Research Institute at Harbor-UCLA, Los Angeles, California, United States of America.
Kallianpur KJ; Hawaii Center for AIDS, Department of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.
Nakamoto BK; Hawaii Center for AIDS, Department of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.; Straub Hospital, Honolulu, Hawaii, United States of America.
Keating SM; Blood Systems Research Institute, San Francisco, California, United States of America.
Norris PJ; Blood Systems Research Institute, San Francisco, California, United States of America.; Department of Laboratory Medicine, University of California, San Francisco, California, United States of America.; Department of Medicine, University of California, San Francisco, California, United States of America.
Ndhlovu LC; Hawaii Center for AIDS, Department of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.; Department of Tropical Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.
Souza SA; Hawaii Center for AIDS, Department of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.
Shikuma CM; Hawaii Center for AIDS, Department of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.
Chow DC; Hawaii Center for AIDS, Department of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, United States of America.
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Źródło:
PloS one [PLoS One] 2016 Feb 11; Vol. 11 (2), pp. e0149143. Date of Electronic Publication: 2016 Feb 11 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Calcium/*metabolism
Cardiovascular Diseases/*complications
Chemokine CCL2/*blood
Coronary Vessels/*physiopathology
HIV Infections/*blood
Monocytes/*cytology
Adult ; Aging ; Anti-Retroviral Agents/therapeutic use ; Biomarkers/blood ; Calcinosis/physiopathology ; Cardiovascular Diseases/drug therapy ; Comorbidity ; Coronary Vessels/pathology ; Disease Progression ; Female ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV-1 ; Hawaii ; Humans ; Inflammation ; Longitudinal Studies ; Male ; Middle Aged ; Phenotype ; Tomography, X-Ray Computed
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection.
Autorzy:
Chew GM; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Fujita T; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.; Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Webb GM; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
Burwitz BJ; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
Wu HL; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
Reed JS; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
Hammond KB; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
Clayton KL; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Ishii N; Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Abdel-Mohsen M; Division of Experimental Medicine, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America.
Liegler T; Division of Experimental Medicine, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America.
Mitchell BI; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Hecht FM; HIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America.
Ostrowski M; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
Shikuma CM; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Hansen SG; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
Maurer M; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, California, United States of America.
Korman AJ; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, California, United States of America.
Deeks SG; HIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, United States of America.
Sacha JB; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Portland, Oregon, United States of America.; Oregon National Primate Research Center, Oregon Health and Science University, Portland, Oregon, United States of America.
Ndhlovu LC; Hawaii Center for HIV/AIDS, Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2016 Jan 07; Vol. 12 (1), pp. e1005349. Date of Electronic Publication: 2016 Jan 07 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
HIV Infections/*immunology
Receptors, Immunologic/*immunology
Animals ; B7-H1 Antigen/immunology ; Cell Separation ; DNA, Viral/analysis ; Disease Progression ; Flow Cytometry ; Humans ; Lymphocyte Activation/immunology ; Macaca mulatta ; RNA, Viral/analysis ; Simian Acquired Immunodeficiency Syndrome/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Symptoms of Autonomic Dysfunction in Human Immunodeficiency Virus.
Autorzy:
Chow D; Hawaii Center for AIDS, Department of Medicine , University of Hawaii.
Nakamoto BK; Hawaii Center for AIDS, Department of Medicine , University of Hawaii ; Straub Clinic and Hospital , Department of Neurology, Honolulu, Hawaii.
Sullivan K; Hawaii Center for AIDS, Department of Medicine , University of Hawaii.
Sletten DM; Mayo Clinic, Rochester, Minnesota.
Fujii S; Hawaii Center for AIDS, Department of Medicine , University of Hawaii.
Umekawa S; Hawaii Center for AIDS, Department of Medicine , University of Hawaii.
Kocher M; Hawaii Center for AIDS, Department of Medicine , University of Hawaii.
Kallianpur KJ; Hawaii Center for AIDS, Department of Medicine , University of Hawaii.
Shikuma CM; Hawaii Center for AIDS, Department of Medicine , University of Hawaii.
Low P; Mayo Clinic, Rochester, Minnesota.
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Źródło:
Open forum infectious diseases [Open Forum Infect Dis] 2015 Jul 08; Vol. 2 (3), pp. ofv103. Date of Electronic Publication: 2015 Jul 08 (Print Publication: 2015).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV.
Autorzy:
Shikuma CM; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
Chow DC; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
Gangcuangco LM; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
Zhang G; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
Keating SM; Blood Systems Research Institute, San Francisco, California, United States of America.
Norris PJ; Blood Systems Research Institute, San Francisco, California, United States of America ; University of California San Francisco, San Francisco, California, United States of America.
Seto TB; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America ; Queen's Medical Center, Honolulu, Hawaii, United States of America.
Parikh N; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America ; Queen's Medical Center, Honolulu, Hawaii, United States of America.
Kallianpur KJ; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
Nakamoto BK; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America ; Straub Clinic and Hospital, Honolulu, Hawaii, United States of America.
Nagamine LS; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
Ndhlovu LC; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
Barbour JD; Hawaii Center for AIDS, University of Hawaii, Honolulu, Hawaii, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Feb 27; Vol. 9 (2), pp. e90330. Date of Electronic Publication: 2014 Feb 27 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
HIV Infections/*immunology
HIV Infections/*metabolism
Insulin Resistance/*immunology
Monocytes/*immunology
Age Factors ; Biomarkers/blood ; Biomarkers/metabolism ; Blood Glucose ; Cross-Sectional Studies ; Diabetes Mellitus/diagnosis ; Diabetes Mellitus/immunology ; Diabetes Mellitus/metabolism ; Female ; Humans ; Immunophenotyping ; Lymphocyte Count ; Male ; Metabolic Syndrome/immunology ; Metabolic Syndrome/metabolism ; Middle Aged ; Monocytes/metabolism ; Risk Factors ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
IL-1Β enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease.
Autorzy:
Jalbert E; Hawaii Center for HIV/AIDS, Honolulu, Hawaii, United States of America ; Department of Tropical Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.
Crawford TQ
D'Antoni ML
Keating SM
Norris PJ
Nakamoto BK
Seto T
Parikh NI
Shikuma CM
Ndhlovu LC
Barbour JD
Pokaż więcej
Źródło:
PloS one [PLoS One] 2013 Sep 25; Vol. 8 (9), pp. e75500. Date of Electronic Publication: 2013 Sep 25 (Print Publication: 2013).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Anti-Retroviral Agents/*therapeutic use
Cardiovascular Diseases/*immunology
HIV Infections/*immunology
HIV-1/*immunology
Inflammation/*immunology
Interleukin-1beta/*immunology
Interleukin-6/*immunology
Monocytes/*immunology
Cardiovascular Diseases/etiology ; Cardiovascular Diseases/metabolism ; Female ; HIV Infections/drug therapy ; HIV Infections/metabolism ; HIV-1/drug effects ; Humans ; Inflammation/metabolism ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Interleukin-8/immunology ; Interleukin-8/metabolism ; Male ; Middle Aged ; Monocytes/drug effects ; Monocytes/metabolism ; Risk ; Tumor Necrosis Factor-alpha/immunology ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 27

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