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Wyszukujesz frazę ""Sinilnikova OM"" wg kryterium: Autor


Tytuł:
Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.
Autorzy:
Mulligan AM
Couch FJ
Barrowdale D
Domchek SM
Eccles D
Nevanlinna H
Ramus SJ
Robson M
Sherman M
Spurdle AB
Wappenschmidt B
Lee A
McGuffog L
Healey S
Sinilnikova OM
Janavicius R
Hansen Tv
Nielsen FC
Ejlertsen B
Osorio A
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Źródło:
Breast Cancer Research; 2011, Vol. 13 Issue 6, pR110-R110, 1p
Czasopismo naukowe
Tytuł:
GENESIS: a French national resource to study the missing heritability of breast cancer.
Autorzy:
Sinilnikova OM; Cancer Research Centre of Lyon, CNRS UMR5286, Inserm U1052, Université Claude Bernard Lyon 1, Centre Léon Bérard, Lyon, France.; Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon, Centre Léon Bérard, Lyon, France.
Dondon MG; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
Eon-Marchais S; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
Damiola F; Cancer Research Centre of Lyon, CNRS UMR5286, Inserm U1052, Université Claude Bernard Lyon 1, Centre Léon Bérard, Lyon, France. .
Barjhoux L; Cancer Research Centre of Lyon, CNRS UMR5286, Inserm U1052, Université Claude Bernard Lyon 1, Centre Léon Bérard, Lyon, France. .
Marcou M; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
Verny-Pierre C; Cancer Research Centre of Lyon, CNRS UMR5286, Inserm U1052, Université Claude Bernard Lyon 1, Centre Léon Bérard, Lyon, France. .
Sornin V; Cancer Research Centre of Lyon, CNRS UMR5286, Inserm U1052, Université Claude Bernard Lyon 1, Centre Léon Bérard, Lyon, France. .
Toulemonde L; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
Beauvallet J; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
Le Gal D; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
Mebirouk N; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
Belotti M; Institut Curie, Service de Génétique, Paris, France. .
Caron O; Institut de Cancérologie Gustave Roussy, Service d'Oncologie Génétique, Villejuif, France. .
Gauthier-Villars M; Institut Curie, Service de Génétique, Paris, France. .
Coupier I; Hôpital Arnaud de Villeneuve, CHU Montpellier, Service de Génétique médicale et Oncogénétique, Montpellier, France. .; ICM Val d'Aurel, Unité d'Oncogénétique, Montpellier, France. .
Buecher B; Institut Curie, Service de Génétique, Paris, France. .
Lortholary A; Centre Catherine de Sienne, Service d'Oncologie Médicale, Nantes, France. .
Dugast C; Centre Eugène-Marquis, Service de Génétique, Rennes, France. .
Gesta P; CH Georges Renon, Service Oncogénétique pour la consultation oncogénétique régionale Poitou-Charentes, Niort, France. .
Fricker JP; Centre Paul Strauss, Unité d'Oncologie, Strasbourg, France. .
Noguès C; Institut Curie, Hôpital René Huguenin, Saint-Cloud, France. .
Faivre L; Hôpital d'Enfants, Service de Génétique Médicale, Dijon, France. .; Centre Georges François Leclerc, Oncogénétique, Dijon, France. .
Luporsi E; ICL Alexis Vautrin, Unité d'Oncogénétique, Vandœuvre-lès-Nancy, France. .
Berthet P; Centre François Baclesse, Unité de pathologie gynécologique, Caen, France. .
Delnatte C; Centre René Gauducheau, Unité d'Oncogénétique, Nantes Saint Herblain, France. .
Bonadona V; Université Claude Bernard Lyon 1, Villeurbanne, France. .; CNRS UMR 5558, Lyon, France. .; Centre Léon Bérard, Unité de Prévention et Epidémiologie Génétique, Lyon, France. .
Maugard CM; Hôpitaux Universitaires de Strasbourg, UF1422 Oncogénétique moléculaire, Laboratoire de diagnostic génétique, Strasbourg, France. .; Hôpitaux Universitaires de Strasbourg, UF6948 Oncogénétique, Service d'Hémato-Oncologie, Strasbourg, France. .
Pujol P; Hôpital Arnaud de Villeneuve, CHU Montpellier, Service de Génétique médicale et Oncogénétique, Montpellier, France. .; Inserm, U896, CRCM Val d'Aurel, Montpellier, France. .
Lasset C; Université Claude Bernard Lyon 1, Villeurbanne, France. .; CNRS UMR 5558, Lyon, France. .; Centre Léon Bérard, Unité de Prévention et Epidémiologie Génétique, Lyon, France. .
Longy M; Institut Bergonié, Bordeaux, France. .
Bignon YJ; Centre Jean-Perrin, Clermont-Ferrand, France. .
Adenis C; Centre Oscar-Lambret, Lille, France. .
Venat-Bouvet L; Hôpital Universitaire Dupuytren, Service d'Oncologie Médicale, Limoges, France. .
Demange L; Polyclinique Courlancy, Reims, France.
Dreyfus H; Clinique Sainte Catherine, Avignon, France. .; CHU de Grenoble, Hôpital Couple-Enfant, Département de Génétique, Grenoble, France. .
Frenay M; Centre Antoine Lacassagne, Unité d'Oncogénétique, Nice, France. .
Gladieff L; Institut Claudius Regaud - IUCT-Oncopole, Service d'Oncologie Médicale, Toulouse, France. .
Mortemousque I; Hôpital Bretonneau, Service de Génétique, Tours, France. .
Audebert-Bellanger S; CHU Brest, Hôpital Morvan, Département de génétique médicale en pédiatrie, Brest, France. .
Soubrier F; Hôpital Tenon, Paris, France. .
Giraud S; Hôpital Edouard Herriot, Service de Génétique Moléculaire, Lyon, France. .
Lejeune-Dumoulin S; Hôpital Jeanne de Flandre, Service de génétique clinique Guy Fontaine, Lille, France. .
Chevrier A; Hôpital Universitaire de Rouen, Département de Génétique, Rouen, France. .
Limacher JM; Hôpital Pasteur, Service d'Onco-hématologie, Colmar, France. .
Chiesa J; CHRU Hôpital Caremeau, Nîmes, France. .
Fajac A; Hôpital Tenon, Service d'Oncogénétique, Paris, France. .
Floquet A; Institut Bergonié, Bordeaux, France. .
Eisinger F; IPC, Département d'Anticipation et de Suivi des Cancers, Marseille, France. .; Inserm, UMR 912, Marseille, France. .
Tinat J; Hôpital Universitaire de Rouen, Département de Génétique, Rouen, France. .
Colas C; Groupe Hospitalier Pitié-Salpêtrière, Département de Génétique, APHP, Paris, France. .
Fert-Ferrer S; Centre Hospitalier de Chambéry, Chambéry, France. .
Penet C; Institut Jean-Godinot, Reims, France. .; ICC Courlancy, Cs Oncogénétique, Reims, France. .
Frebourg T; Hôpital Universitaire de Rouen, Département de Génétique, Rouen, France. .
Collonge-Rame MA; CHU Hôpital Saint-Jacques, Service Génétique et Biologie du Développement - Histologie, Besançon, France. .
Barouk-Simonet E; Institut Bergonié, Bordeaux, France. .
Layet V; Hôpital Flaubert, Le Havre, France. .
Leroux D; CHU de Grenoble, Hôpital Couple-Enfant, Département de Génétique, Grenoble, France. .
Cohen-Haguenauer O; Hôpital Saint-Louis, Paris, France. .
Prieur F; CHU de Saint-Etienne, Hôpital Nord, Service de Génétique, Saint-Etienne, France. .
Mouret-Fourme E; Institut Curie, Hôpital René Huguenin, Saint-Cloud, France. .
Cornélis F; Hôpital Lariboisière, Centre Viggo-Petersen, Paris, France. .
Jonveaux P; CHU Hôpital de Brabois, Laboratoire de Génétique, Vandœuvre-lès-Nancy, France. .
Bera O; CHU de Martinique, Unité d'Oncogénétique, Fort-de-France, France. .
Cavaciuti E; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
Tardivon A; Institut Curie, Département d'imagerie médicale, Paris, France. .
Lesueur F; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
Mazoyer S; Cancer Research Centre of Lyon, CNRS UMR5286, Inserm U1052, Université Claude Bernard Lyon 1, Centre Léon Bérard, Lyon, France. .
Stoppa-Lyonnet D; PSL Research University, Paris, France. .; Institut Curie, Service de Génétique, Paris, France. .; Inserm, U830, Paris, France. .; Université Paris-Descartes, Paris, France. .
Andrieu N; Inserm, U900, Paris, France. .; Institut Curie, Paris, France. .; PSL Research University, Paris, France. .; Mines ParisTech, Fontainebleau, France. .
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Źródło:
BMC cancer [BMC Cancer] 2016 Jan 12; Vol. 16, pp. 13. Date of Electronic Publication: 2016 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Germ-Line Mutation*
Breast Neoplasms/*epidemiology
Breast Neoplasms/*genetics
Neoplasm Proteins/*genetics
Adult ; Aged ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Breast Neoplasms/pathology ; Female ; France/epidemiology ; Genetic Predisposition to Disease ; Genetic Testing ; Humans ; Middle Aged
SCR Disease Name:
Breast Cancer, Familial
Czasopismo naukowe
Tytuł:
Targeted Sequencing of the Mitochondrial Genome of Women at High Risk of Breast Cancer without Detectable Mutations in BRCA1/2.
Autorzy:
Blein S; INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
Barjhoux L; INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
Damiola F; INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
Dondon MG; Inserm, U900, Paris, France; Institut Curie, Paris, France; Mines ParisTech, Fontainebleau, France.
Eon-Marchais S; Inserm, U900, Paris, France; Institut Curie, Paris, France; Mines ParisTech, Fontainebleau, France.
Marcou M; Inserm, U900, Paris, France.
Caron O; Consultation de Génétique, Département de Médecine, Institut de Cancérologie Gustave Roussy, Villejuif, France.
Lortholary A; Centre Catherine de Sienne, Nantes, France.
Buecher B; Institut Curie, Department of Tumour Biology, Paris, France.
Vennin P; Département de Cancérologie sénologique, CLCC Oscar Lambret, Lille, France.
Berthet P; Centre François Baclesse, Caen, France.
Noguès C; Oncogénétique Clinique, Hôpital René Huguenin/Institut Curie, Saint-Cloud, France.
Lasset C; Université Lyon 1, CNRS UMR5558, Lyon, France; Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France.
Gauthier-Villars M; Consultation de Génétique, Département de Médecine, Institut de Cancérologie Gustave Roussy, Villejuif, France.
Mazoyer S; INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
Stoppa-Lyonnet D; Consultation de Génétique, Département de Médecine, Institut de Cancérologie Gustave Roussy, Villejuif, France; Institut Curie, INSERM U830, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, France.
Andrieu N; Inserm, U900, Paris, France; Institut Curie, Paris, France; Mines ParisTech, Fontainebleau, France.
Thomas G; Université Lyon 1, INCa-Synergie, Centre Léon Bérard, 28 rue Laennec, Lyon Cedex 08, France.
Sinilnikova OM; INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France; Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, Lyon, France.
Cox DG; INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
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Corporate Authors:
GENESIS investigators
Źródło:
PloS one [PLoS One] 2015 Sep 25; Vol. 10 (9), pp. e0136192. Date of Electronic Publication: 2015 Sep 25 (Print Publication: 2015).
Typ publikacji:
Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms:
BRCA1 Protein*
BRCA2 Protein*
Mutation*
Breast Neoplasms/*genetics
Genome, Mitochondrial/*genetics
Mitochondrial Proton-Translocating ATPases/*genetics
Breast Neoplasms/diagnosis ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Penetrance
Czasopismo naukowe
Tytuł:
Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.
Autorzy:
Blanco I; Hereditary Cancer Program, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Kuchenbaecker K; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
Cuadras D; Statistics Unit, Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Wang X; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, United States of America.
Barrowdale D; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
de Garibay GR; Breast Cancer and Systems Biology Unit, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Librado P; Department of Genetics and Biodiversity Research Institute (IRBio), University of Barcelona, Barcelona, Catalonia, Spain.
Sánchez-Gracia A; Department of Genetics and Biodiversity Research Institute (IRBio), University of Barcelona, Barcelona, Catalonia, Spain.
Rozas J; Department of Genetics and Biodiversity Research Institute (IRBio), University of Barcelona, Barcelona, Catalonia, Spain.
Bonifaci N; Breast Cancer and Systems Biology Unit, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
McGuffog L; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
Pankratz VS; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
Islam A; Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka, Bangladesh.
Mateo F; Breast Cancer and Systems Biology Unit, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Berenguer A; Statistics Unit, Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Petit A; Department of Pathology, University Hospital of Bellvitge, Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Català I; Department of Pathology, University Hospital of Bellvitge, Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Brunet J; Hereditary Cancer Program, Catalan Institute of Oncology (ICO), Girona Biomedical Research Institute (IDIBGI), Hospital Josep Trueta, Girona, Catalonia, Spain.
Feliubadaló L; Hereditary Cancer Program, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Tornero E; Hereditary Cancer Program, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Benítez J; Human Genetics Group, Spanish National Cancer Centre (CNIO), and Biomedical Network on Rare Diseases, Madrid, Spain.
Osorio A; Human Genetics Group, Spanish National Cancer Centre (CNIO), and Biomedical Network on Rare Diseases, Madrid, Spain.
Ramón y Cajal T; Oncology Service, Hospital de la Santa Creu i Sant Pau, Barcelona, Catalonia, Spain.
Nevanlinna H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
Aittomäki K; Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland.
Arun BK; Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.
Toland AE; Division of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America.
Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
Walsh C; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
Lester J; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America.
Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Maryland, Rockville, United States of America.
Mai PL; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Maryland, Rockville, United States of America.
Nussbaum RL; Department of Medicine and Genetics, University of California San Francisco, San Francisco, California, United States of America.
Andrulis IL; Samuel Lunenfeld Research Institute, Mount Sinai Hospital, and Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Domchek SM; Abramson Cancer Center and Department of Medicine, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.
Nathanson KL; Abramson Cancer Center and Department of Medicine, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.
Rebbeck TR; Abramson Cancer Center and Center for Clinical Epidemiology and Biostatistics, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Barkardottir RB; Department of Pathology, Landspitali University Hospital and BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Lubinski J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Durda K; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Jaworska-Bieniek K; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Claes K; Center for Medical Genetics, Ghent University, Ghent, Belgium.
Van Maerken T; Center for Medical Genetics, Ghent University, Ghent, Belgium.
Díez O; Oncogenetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Research Institute (VHIR) and Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain.
Hansen TV; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Jønson L; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Gerdes AM; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Ejlertsen B; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
de la Hoya M; Molecular Oncology Laboratory, Hospital Clínico San Carlos, San Carlos Research Institute (IdISSC), Madrid, Spain.
Caldés T; Molecular Oncology Laboratory, Hospital Clínico San Carlos, San Carlos Research Institute (IdISSC), Madrid, Spain.
Dunning AM; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
Oliver C; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
Fineberg E; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
Cook M; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
Peock S; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
McCann E; All Wales Medical Genetics Service, Glan Clwyd Hospital, Rhyl, United Kingdom.
Murray A; All Wales Medical Genetics Services, Singleton Hospital, Swansea, United Kingdom.
Jacobs C; Clinical Genetics, Guy's and St. Thomas' National Health Service (NHS) Foundation Trust, London, United Kingdom.
Pichert G; Clinical Genetics, Guy's and St. Thomas' National Health Service (NHS) Foundation Trust, London, United Kingdom.
Lalloo F; Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals National Health Service (NHS) Foundation Trust, Manchester, United Kingdom.
Chu C; Yorkshire Regional Genetics Service, Leeds, United Kingdom.
Dorkins H; North West Thames Regional Genetics Service, Kennedy-Galton Centre, Harrow, United Kingdom.
Paterson J; Department of Clinical Genetics, East Anglian Regional Genetics Service, Addenbrookes Hospital, Cambridge, United Kingdom.
Ong KR; West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare National Health Service (NHS) Trust, Edgbaston, Birmingham, United Kingdom.
Teixeira MR; Department of Genetics, Portuguese Oncology Institute, and Biomedical Sciences Institute (ICBAS), Porto University, Porto, Portugal.
Hogervorst FB; Family Cancer Clinic, Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands.
van der Hout AH; Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands.
Seynaeve C; Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands.
van der Luijt RB; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.
Ligtenberg MJ; Department of Human Genetics and Department of Pathology, Radboud university medical center, Nijmegen, The Netherlands.
Devilee P; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Wijnen JT; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands; Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Rookus MA; Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Meijers-Heijboer HE; Department of Clinical Genetics, Vrije Universiteit (VU) University Medical Centre, Amsterdam, The Netherlands.
Blok MJ; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands.
van den Ouweland AM; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Aalfs CM; Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands.
Rodriguez GC; Division of Gynecologic Oncology, NorthShore University HealthSystem, University of Chicago, Chicago, Illinois, United States of America.
Phillips KA; Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.
Piedmonte M; Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo, New York, United States of America.
Nerenstone SR; Central Connecticut Cancer Consortium, Hartford Hospital/Helen and Harry Gray Cancer Center, Hartford, Connecticut, United States of America.
Bae-Jump VL; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, North Carolina, United States of America.
O'Malley DM; Division of Gynecologic Oncology, Ohio State University, Columbus Cancer Council, Hilliard, Ohio, United States of America.
Ratner ES; Division of Gynecologic Oncology, Yale University School of Medicine, New Haven, Connecticut, United States of America.
Schmutzler RK; Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany.
Wappenschmidt B; Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany.
Rhiem K; Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany.
Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
Meindl A; Department of Gynecology and Obstetrics, Division of Tumor Genetics, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany.
Ditsch N; Department of Gynecology and Obstetrics, Ludwig-Maximilian University Munich, Munich, Germany.
Arnold N; Department of Gynecology and Obstetrics, Christian-Albrechts-University of Kiel University Medical Center Schleswig-Holstein, Kiel, Germany.
Plendl HJ; Institute of Human Genetics, Christian-Albrechts-University of Kiel University Medical Center Schleswig-Holstein, Kiel, Germany.
Niederacher D; Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Sutter C; Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany.
Wang-Gohrke S; Department of Gynecology and Obstetrics, University Hospital Ulm, Ulm, Germany.
Steinemann D; Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.
Preisler-Adams S; Institute of Human Genetics, University of Münster, Münster, Germany.
Kast K; Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Varon-Mateeva R; Institute of Human Genetics, Campus Virchov Klinikum, Charite Berlin, Berlin, Germany.
Gehrig A; Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University Würzburg, Würzburg, Germany.
Bojesen A; Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark.
Pedersen IS; Section of Molecular Diagnostics, Department of Biochemistry, Aalborg University Hospital, Aalborg, Denmark.
Sunde L; Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.
Jensen UB; Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.
Thomassen M; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
Kruse TA; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
Foretova L; Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
Peterlongo P; Fondazione Istituto di Oncologia Molecolare (IFOM), Fondazione Italiana per la Ricerca sul Cancro (FIRC), Milan, Italy.
Bernard L; Department of Experimental Oncology, Istituto Europeo di Oncologia (IEO), Cogentech Cancer Genetic Test Laboratory, Milan, Italy.
Peissel B; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione Istituto Nazionale Tumori (INT), Milan, Italy.
Scuvera G; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione Istituto Nazionale Tumori (INT), Milan, Italy.
Manoukian S; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione Istituto Nazionale Tumori (INT), Milan, Italy.
Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Fondazione Istituto Nazionale Tumori (INT), Milan, Italy.
Ottini L; Department of Molecular Medicine, 'Sapienza' University, Rome, Italy.
Montagna M; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto (IOV), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padua, Italy.
Agata S; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto (IOV), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padua, Italy.
Maugard C; Laboratoire de Diagnostic Génétique et Service d'Onco-Hématologie, Hopitaux Universitaire de Strasbourg, Centre Hospitalier Régional Universitaire (CHRU) Nouvel Hôpital Civil, Strasbourg, France.
Simard J; Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Canada.
Soucy P; Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Canada.
Berger A; Department of Gynecology and Obstetrics, and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Fink-Retter A; Department of Gynecology and Obstetrics, and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Singer CF; Department of Gynecology and Obstetrics, and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Rappaport C; Department of Gynecology and Obstetrics, and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Geschwantler-Kaulich D; Department of Gynecology and Obstetrics, and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Tea MK; Department of Gynecology and Obstetrics, and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Pfeiler G; Department of Gynecology and Obstetrics, and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
John EM; Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California, United States of America.
Miron A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.
Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, United States of America.
Terry MB; Department of Epidemiology, Columbia University, New York, New York, United States of America.
Chung WK; Departments of Pediatrics and Medicine, Columbia University Medical Center, New York, New York, United States of America.
Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America.
Goldgar DE; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.
Janavicius R; Vilnius University Hospital Santariskiu Clinics, Hematology, Oncology and Transfusion Medicine Center, Department of Molecular and Regenerative Medicine, State Research Centre Institute for Innovative medicine, Vilnius, Lithuania.
Dorfling CM; Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Arcadia, South Africa.
van Rensburg EJ; Cancer Genetics Laboratory, Department of Genetics, University of Pretoria, Arcadia, South Africa.
Fostira F; Molecular Diagnostics Laboratory, Institute of Radioisotopes and Radiodiagnostic Products (IRRP), National Centre for Scientific Research Demokritos, Athens, Greece.
Konstantopoulou I; Molecular Diagnostics Laboratory, Institute of Radioisotopes and Radiodiagnostic Products (IRRP), National Centre for Scientific Research Demokritos, Athens, Greece.
Garber J; Center for Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America.
Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Olah E; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.
Narod SA; Women's College Research Institute, University of Toronto, Toronto, Canada.
Rennert G; Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B Rappaport Faculty of Medicine, Haifa, Israel.
Paluch SS; The Institute of Oncology, Chaim Sheba Medical Center, Ramat Gan, Israel.
Laitman Y; The Susanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel.
Friedman E; The Susanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Liljegren A; Department of Oncology, Karolinska University Hospital, Stockholm, Sweden.
Rantala J; Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.
Stenmark-Askmalm M; Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Loman N; Department of Oncology, Lund University Hospital, Lund, Sweden.
Imyanitov EN; N.N. Petrov Institute of Oncology, St.-Petersburg, Russia.
Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Spurdle AB; Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute, Brisbane, Australia.
Healey S; Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute, Brisbane, Australia.
Weitzel JN; Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America.
Herzog J; Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America.
Margileth D; St. Joseph Hospital of Orange, Care of City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California, United States of America.
Gorrini C; The Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, University Health Network, Toronto, Canada.
Esteller M; Cancer Epigenetics and Biology Program (PEBC), IDIBELL, L'Hospitalet del Llobregat, Catalonia, Spain; Department of Physiological Sciences II, School of Medicine, University of Barcelona, L'Hospitalet del Llobregat, Catalonia, Spain; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Catalonia, Spain.
Gómez A; Cancer Epigenetics and Biology Program (PEBC), IDIBELL, L'Hospitalet del Llobregat, Catalonia, Spain.
Sayols S; Cancer Epigenetics and Biology Program (PEBC), IDIBELL, L'Hospitalet del Llobregat, Catalonia, Spain.
Vidal E; Cancer Epigenetics and Biology Program (PEBC), IDIBELL, L'Hospitalet del Llobregat, Catalonia, Spain.
Heyn H; Cancer Epigenetics and Biology Program (PEBC), IDIBELL, L'Hospitalet del Llobregat, Catalonia, Spain.
Stoppa-Lyonnet D; Department of Tumour Biology, Institut Curie, Paris, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U830, Institut Curie, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
Léoné M; Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon-Centre Léon Bérard, Lyon, France.
Barjhoux L; Institut National de la Santé et de la Recherche Médicale (INSERM) U1052, Centre National de la Recherche Scientifique (CNRS) UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
Fassy-Colcombet M; Department of Tumour Biology, Institut Curie, Paris, France.
de Pauw A; Department of Tumour Biology, Institut Curie, Paris, France.
Lasset C; Université Lyon 1, Centre National de la Recherche Scientifique (CNRS) UMR5558, and Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France.
Ferrer SF; Laboratoire de Génétique Chromosomique, Hôtel Dieu Centre Hospitalier, Chambéry, France.
Castera L; Department of Tumour Biology, Institut Curie, Paris, France.
Berthet P; Centre François Baclesse, Caen, France.
Cornelis F; Genetic Unit, Avicenne Hospital, Assitance Publique-Hôpitaux de Paris, Paris, Sud-Francilien Hospital, Evry-Corbeil, and University Hospital, Clermont-Ferrand, France.
Bignon YJ; Département d'Oncogénétique, Centre Jean Perrin, Université de Clermont-Ferrand, Clermont-Ferrand, France.
Damiola F; Institut National de la Santé et de la Recherche Médicale (INSERM) U1052, Centre National de la Recherche Scientifique (CNRS) UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
Mazoyer S; Institut National de la Santé et de la Recherche Médicale (INSERM) U1052, Centre National de la Recherche Scientifique (CNRS) UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
Sinilnikova OM; Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon-Centre Léon Bérard, Lyon, France; Institut National de la Santé et de la Recherche Médicale (INSERM) U1052, Centre National de la Recherche Scientifique (CNRS) UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France.
Maxwell CA; Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada.
Vijai J; Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.
Robson M; Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.
Kauff N; Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.
Corines MJ; Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.
Villano D; Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.
Cunningham J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, United States of America; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
Lee A; Department of Oncology, Mayo Clinic, Rochester, Minnesota, United States of America.
Lindor N; Center for Individualized Medicine, Mayo Clinic, Scottsdale, Arizona, United States of America.
Lázaro C; Hereditary Cancer Program, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
Easton DF; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
Offit K; Clinical Genetics Research Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.
Chenevix-Trench G; Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute, Brisbane, Australia.
Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, United States of America; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
Antoniou AC; Epidemiological Study of Familial Breast Cancer (EMBRACE), Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
Pujana MA; Breast Cancer and Systems Biology Unit, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.
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Corporate Authors:
Teixeira
BCFR
SWE-BRCA
kConFab Investigators
GEMO
Źródło:
PloS one [PLoS One] 2015 Apr 01; Vol. 10 (4), pp. e0120020. Date of Electronic Publication: 2015 Apr 01 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Genes, BRCA1*
Genes, BRCA2*
Mutation*
Breast Neoplasms/*genetics
Genetic Predisposition to Disease/*genetics
Aurora Kinase A/genetics ; Breast Neoplasms/enzymology ; Breast Neoplasms/pathology ; Carcinogenesis/genetics ; Cell Cycle Proteins/genetics ; Estrogen Receptor alpha/metabolism ; Evolution, Molecular ; Extracellular Matrix Proteins/genetics ; Female ; Genetic Loci/genetics ; Humans ; Hyaluronan Receptors/genetics ; Likelihood Functions ; Mammary Glands, Human/metabolism ; Microtubule-Associated Proteins/genetics ; Nuclear Proteins/genetics ; Polymorphism, Single Nucleotide ; Retrospective Studies ; Tubulin/genetics
Czasopismo naukowe

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