Autor: "Strug LJ" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: HostSeq: a Canadian whole genome sequencing and clinical data resource
Autorzy:: Yoo, SAff1, Aff2
Garg, E
Elliott, LT
Hung, RJAff4, Aff5
Halevy, AR
Brooks, JD
Bull, SBAff4, Aff5
Gagnon, F
Greenwood, CMTAff6, Aff7
Lawless, JF
Paterson, ADAff1, Aff4
Sun, L
Zawati, MH
Lerner-Ellis, JAff4, Aff9
Abraham, RJS
Birol, I
Bourque, G
Garant, J-M
Gosselin, C
Li, J
Whitney, J
Thiruvahindrapuram, B
Herbrick, J-A
Lorenti, M
Reuter, MS
Adeoye, OO
Liu, S
Allen, UAff1, Aff4
Bernier, FPAff11, Aff12
Biggs, CMAff13, Aff14, Aff15
Cheung, AM
Cowan, JAff2, Aff17
Herridge, M
Maslove, DM
Modi, BP
Mooser, V
Morris, SKAff1, Aff4
Ostrowski, MAff4, Aff19
Parekh, RSAff1, Aff4, Aff20
Pfeffer, G
Suchowersky, O
Taher, JAff4, Aff9
Upton, JAff1, Aff4
Warren, RL
Yeung, RSMAff1, Aff4
Aziz, N
Turvey, SEAff13, Aff14
Knoppers, BM
Lathrop, M
Jones, SJM
Scherer, SWAff1, Aff4
Strug, LJAff1, Aff4, IDs12863023011283_cor52; Pokaż więcej
Źródło:: BMC Genomic Data. 24(1)

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Skocz do pozycji: 2.

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Skocz do pozycji: 3.

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Skocz do pozycji: 4.

Tytuł:: Canadian COVID-19 host genetics cohort replicates known severity associations.
Autorzy:: Garg E; Department of Statistics and Actuarial Science, Simon Fraser University, Vancouver, British Columbia, Canada.; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Arguello-Pascualli P; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
Vishnyakova O; Department of Statistics and Actuarial Science, Simon Fraser University, Vancouver, British Columbia, Canada.; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Halevy AR; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Yoo S; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada.
Brooks JD; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Bull SB; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, Ontario, Canada.
Gagnon F; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Greenwood CMT; Gerald Bronfman Department of Oncology, Department of Epidemiology, Biostatistics and Occupational Health, Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.
Hung RJ; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, Ontario, Canada.
Lawless JF; Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.
Lerner-Ellis J; Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, Ontario, Canada.; Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Dennis JK; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
Abraham RJS; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Garant JM; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Thiruvahindrapuram B; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Jones SJM; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
Strug LJ; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Department of Statistical Sciences, University of Toronto, Toronto, Ontario, Canada.
Paterson AD; Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Sun L; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Department of Statistical Sciences, University of Toronto, Toronto, Ontario, Canada.
Elliott LT; Department of Statistics and Actuarial Science, Simon Fraser University, Vancouver, British Columbia, Canada.; Pokaż więcej
Corporate Authors:: CGEn HostSeq Initiative
Źródło:: PLoS genetics [PLoS Genet] 2024 Mar 22; Vol. 20 (3), pp. e1011192. Date of Electronic Publication: 2024 Mar 22 (Print Publication: 2024).
Typ publikacji:: Meta-Analysis; Journal Article
MeSH Terms:: COVID-19*/genetics
North American People*
Humans ; SARS-CoV-2/genetics ; Genetic Predisposition to Disease ; Polymorphism, Single Nucleotide ; Canada/epidemiology ; Genome-Wide Association Study ; Membrane Transport Proteins ; Forkhead Transcription Factors

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Skocz do pozycji: 5.

Tytuł:: HostSeq: a Canadian whole genome sequencing and clinical data resource.
Autorzy:: Yoo S; The Hospital for Sick Children, Toronto, ON, Canada.; University of Ottawa, Ottawa, ON, Canada.
Garg E; Simon Fraser University, Burnaby, BC, Canada.
Elliott LT; Simon Fraser University, Burnaby, BC, Canada.
Hung RJ; University of Toronto, Toronto, ON, Canada.; Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON, Canada.
Halevy AR; The Hospital for Sick Children, Toronto, ON, Canada.
Brooks JD; University of Toronto, Toronto, ON, Canada.
Bull SB; University of Toronto, Toronto, ON, Canada.; Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON, Canada.
Gagnon F; University of Toronto, Toronto, ON, Canada.
Greenwood C; McGill University, Montreal, QC, Canada.; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada.
Lawless JF; University of Waterloo, Waterloo, ON, Canada.
Paterson AD; The Hospital for Sick Children, Toronto, ON, Canada.; University of Toronto, Toronto, ON, Canada.
Sun L; University of Toronto, Toronto, ON, Canada.
Zawati MH; McGill University, Montreal, QC, Canada.
Lerner-Ellis J; University of Toronto, Toronto, ON, Canada.; Sinai Health System, Toronto, ON, Canada.
Abraham R; Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Birol I; Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Bourque G; McGill University, Montreal, QC, Canada.
Garant JM; Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Gosselin C; Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Li J; Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Whitney J; The Hospital for Sick Children, Toronto, ON, Canada.
Thiruvahindrapuram B; The Hospital for Sick Children, Toronto, ON, Canada.
Herbrick JA; The Hospital for Sick Children, Toronto, ON, Canada.
Lorenti M; The Hospital for Sick Children, Toronto, ON, Canada.
Reuter MS; The Hospital for Sick Children, Toronto, ON, Canada.
Adeoye OO; The Hospital for Sick Children, Toronto, ON, Canada.
Liu S; The Hospital for Sick Children, Toronto, ON, Canada.
Allen U; The Hospital for Sick Children, Toronto, ON, Canada.; University of Toronto, Toronto, ON, Canada.
Bernier FP; University of Calgary, Calgary, AB, Canada.; Alberta Children's Hospital, Calgary, AB, Canada.
Biggs CM; University of British Columbia, Vancouver, BC, Canada.; BC Children's Hospital, Vancouver, BC, Canada.; St. Paul's Hospital, Vancouver, BC, Canada.
Cheung AM; University Health Network, Toronto, ON, Canada.
Cowan J; University of Ottawa, Ottawa, ON, Canada.; The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Herridge M; University Health Network, Toronto, ON, Canada.
Maslove DM; Queen's University, Kingston, ON, Canada.
Modi BP; BC Children's Hospital, Vancouver, BC, Canada.
Mooser V; McGill University, Montreal, QC, Canada.
Morris SK; The Hospital for Sick Children, Toronto, ON, Canada.; University of Toronto, Toronto, ON, Canada.
Ostrowski M; University of Toronto, Toronto, ON, Canada.; St. Michael's Hospital, Unity Health, Toronto, ON, Canada.
Parekh RS; The Hospital for Sick Children, Toronto, ON, Canada.; University of Toronto, Toronto, ON, Canada.; Women's College Hospital, Toronto, ON, Canada.
Pfeffer G; University of Calgary, Calgary, AB, Canada.
Suchowersky O; University of Alberta, Edmonton, AB, Canada.
Taher J; University of Toronto, Toronto, ON, Canada.; Sinai Health System, Toronto, ON, Canada.
Upton J; The Hospital for Sick Children, Toronto, ON, Canada.; University of Toronto, Toronto, ON, Canada.
Warren RL; Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Yeung R; The Hospital for Sick Children, Toronto, ON, Canada.; University of Toronto, Toronto, ON, Canada.
Aziz N; The Hospital for Sick Children, Toronto, ON, Canada.
Turvey SE; University of British Columbia, Vancouver, BC, Canada.; BC Children's Hospital, Vancouver, BC, Canada.
Knoppers BM; McGill University, Montreal, QC, Canada.
Lathrop M; McGill University, Montreal, QC, Canada.
Jones S; Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Scherer SW; The Hospital for Sick Children, Toronto, ON, Canada.; University of Toronto, Toronto, ON, Canada.
Strug LJ; The Hospital for Sick Children, Toronto, ON, Canada. lisa.strug@utoronto.ca.; University of Toronto, Toronto, ON, Canada. lisa.strug@utoronto.ca.; Pokaż więcej
Źródło:: BMC genomic data [BMC Genom Data] 2023 May 02; Vol. 24 (1), pp. 26. Date of Electronic Publication: 2023 May 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: SARS-CoV-2*/genetics
COVID-19*/epidemiology
Humans ; Canada/epidemiology ; Genomics ; Whole Genome Sequencing

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Skocz do pozycji: 6.

Tytuł:: Sex-specific disease modifiers in juvenile myoclonic epilepsy.
Autorzy:: Shakeshaft A; Department of Basic and Clinical Neurosciences, Maurice Wohl Clinical Neurosciences Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 5 Cutcombe Road, London, SE5 9RX, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.
Panjwani N; Program in Genetics and Genome Biology, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada.
Collingwood A; Department of Basic and Clinical Neurosciences, Maurice Wohl Clinical Neurosciences Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 5 Cutcombe Road, London, SE5 9RX, UK.
Crudgington H; Department of Basic and Clinical Neurosciences, Maurice Wohl Clinical Neurosciences Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 5 Cutcombe Road, London, SE5 9RX, UK.
Hall A; Department of Basic and Clinical Neurosciences, Maurice Wohl Clinical Neurosciences Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 5 Cutcombe Road, London, SE5 9RX, UK.
Andrade DM; Adult Epilepsy Genetics Program, Krembil Research Institute, University of Toronto, Toronto, Canada.
Beier CP; Odense University Hospital, Odense, Denmark.
Fong CY; Division of Paediatric Neurology, Department of Paediatrics, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Gardella E; Danish Epilepsy Centre, Dianalund, Denmark.
Gesche J; Odense University Hospital, Odense, Denmark.
Greenberg DA; Nationwide Children's Hospital, Columbus, OH, USA.
Hamandi K; Cardiff and Vale University Health Board, Cardiff, UK.
Koht J; Department of Neurology, Oslo University Hospital, Oslo, Norway.
Lim KS; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Møller RS; Danish Epilepsy Centre, Dianalund, Denmark.; Department of Regional Health Services, University of Southern Denmark, Odense, Denmark.
Ng CC; Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.
Orsini A; Department of Clinical and Experimental Medicine, Pisa University Hospital, Pisa, Italy.
Rees MI; Neurology Research Group, Swansea University Medical School, Swansea, UK.
Rubboli G; Danish Epilepsy Centre, Dianalund, Denmark.; University of Copenhagen, Copenhagen, Denmark.
Selmer KK; Division of Clinical Neuroscience, Department of Research and Innovation, Oslo University Hospital, Oslo, Norway.; National Centre for Epilepsy, Oslo University Hospital, Oslo, Norway.
Striano P; IRCCS Istituto 'G. Gaslini', Genoa, Italy.; University of Genova, Genoa, Italy.
Syvertsen M; Department of Neurology, Drammen Hospital, Vestre Viken Health Trust, Oslo, Norway.
Thomas RH; Newcastle Upon Tyne NHS Foundation Trust, Newcastle, UK.; Faculty of Medical Sciences, Translational and Clinical Research Institute, Newcastle University, Newcastle, UK.
Zarubova J; Department of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
Richardson MP; Department of Basic and Clinical Neurosciences, Maurice Wohl Clinical Neurosciences Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 5 Cutcombe Road, London, SE5 9RX, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.; King's College Hospital, London, UK.
Strug LJ; Program in Genetics and Genome Biology, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada. Lisa.Strug@utoronto.ca.; Departments of Statistical Sciences and Computer Science and Division of Biostatistics, The University of Toronto, Toronto, Canada. Lisa.Strug@utoronto.ca.
Pal DK; Department of Basic and Clinical Neurosciences, Maurice Wohl Clinical Neurosciences Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 5 Cutcombe Road, London, SE5 9RX, UK. .; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK. .; King's College Hospital, London, UK. .; Evelina London Children's Hospital, London, UK. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Feb 21; Vol. 12 (1), pp. 2785. Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Myoclonic Epilepsy, Juvenile*/drug therapy
Myoclonic Epilepsy, Juvenile*/epidemiology
Myoclonic Epilepsy, Juvenile*/etiology
Myoclonic Epilepsy, Juvenile*/physiopathology
Sex Characteristics*
Adolescent ; Adult ; Child ; Cross-Sectional Studies ; Drug Resistance ; Epilepsies, Myoclonic ; Epilepsy, Absence ; Female ; Humans ; Male ; Middle Aged ; Photosensitivity Disorders ; Prognosis ; Seizures ; Young Adult
SCR Disease Name:: Photoparoxysmal Response 3

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Skocz do pozycji: 7.

Tytuł:: Trait impulsivity in Juvenile Myoclonic Epilepsy.
Autorzy:: Shakeshaft A; Department of Basic & Clinical Neurosciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, UK.
Panjwani N; The Hospital for Sick Children, Toronto, Canada.
McDowall R; Department of Basic & Clinical Neurosciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Crudgington H; Department of Basic & Clinical Neurosciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Peña Ceballos J; Department of Basic & Clinical Neurosciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Andrade DM; Toronto Western Hospital, Canada.
Beier CP; Odense University Hospital, Odense, Denmark.
Fong CY; Division of Paediatric Neurology, Department of Paediatrics, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Gesche J; Odense University Hospital, Odense, Denmark.
Greenberg DA; Nationwide Children's Hospital, Ohio.
Hamandi K; Cardiff & Vale University Health Board, UK.
Koht J; Department of Neurology, Drammen Hospital, Vestre Viken Health Trust, Oslo, Norway.; University of Oslo, Oslo, Norway.
Lim KS; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Orsini A; Department of Clinical & Experimental Medicine, Pisa University Hospital, Italy.
Rees MI; Neurology Research Group, Swansea University Medical School, UK.
Rubboli G; Danish Epilepsy Centre, Dianalund, Denmark.; University of Copenhagen, Denmark.
Selmer KK; Department of Research and Innovation, Division of Clinical Neuroscience, Oslo University Hospital, Norway.; National Centre for Epilepsy, Oslo University Hospital, Norway.
Smith AB; Department of Basic & Clinical Neurosciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Striano P; IRCCS Istituto 'G. Gaslini', Genova, Italy.; University of Genova, Genova, Italy.
Syvertsen M; Department of Neurology, Drammen Hospital, Vestre Viken Health Trust, Oslo, Norway.
Talvik I; Tallin Children's Hospital, Tallin, Estonia.
Thomas RH; Newcastle upon Tyne NHS Foundation Trust, Newcastle, UK.
Zarubova J; Department of Neurology, Motol University Hospital, Prague, Czech Republic.; Second Faculty of Medicine, Charles University, Prague, Czech Republic.
Richardson MP; Department of Basic & Clinical Neurosciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, UK.; King's College Hospital, London, UK.
Strug LJ; The Hospital for Sick Children, Toronto, Canada.
Pal DK; Department of Basic & Clinical Neurosciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, UK.; King's College Hospital, London, UK.; Evelina London Children's Hospital, London, UK.; Pokaż więcej
Corporate Authors:: BIOJUME Consortium
Źródło:: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2021 Jan; Vol. 8 (1), pp. 138-152. Date of Electronic Publication: 2020 Dec 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Impulsive Behavior*
Myoclonic Epilepsy, Juvenile/*psychology
Adolescent ; Adult ; Child ; Female ; Humans ; Male ; Young Adult

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Skocz do pozycji: 8.

Tytuł:: Statistical power in COVID-19 case-control host genomic study design.
Autorzy:: Lin YC; Dalla Lana School of Public Health, University of Toronto, Room 500, 155 College St, Toronto, ON, M5T3M7, Canada.; Program in Genetics and Genome Biology, The Hospital for Sick Children, Room 12.9801, 686 Bay Street, Toronto, ON, M5G0A4, Canada.
Brooks JD; Dalla Lana School of Public Health, University of Toronto, Room 500, 155 College St, Toronto, ON, M5T3M7, Canada.
Bull SB; Dalla Lana School of Public Health, University of Toronto, Room 500, 155 College St, Toronto, ON, M5T3M7, Canada.; Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.
Gagnon F; Dalla Lana School of Public Health, University of Toronto, Room 500, 155 College St, Toronto, ON, M5T3M7, Canada.
Greenwood CMT; Gerald Bronfman Department of Oncology, Department of Epidemiology, Biostatistics & Occupational Health, Department of Human Genetics, McGill University, Montreal, QC, Canada.; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada.
Hung RJ; Dalla Lana School of Public Health, University of Toronto, Room 500, 155 College St, Toronto, ON, M5T3M7, Canada.; Program in Genetics and Genome Biology, The Hospital for Sick Children, Room 12.9801, 686 Bay Street, Toronto, ON, M5G0A4, Canada.
Lawless J; Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada.
Paterson AD; Dalla Lana School of Public Health, University of Toronto, Room 500, 155 College St, Toronto, ON, M5T3M7, Canada.; Program in Genetics and Genome Biology, The Hospital for Sick Children, Room 12.9801, 686 Bay Street, Toronto, ON, M5G0A4, Canada.
Sun L; Dalla Lana School of Public Health, University of Toronto, Room 500, 155 College St, Toronto, ON, M5T3M7, Canada.; Department of Statistical Sciences, University of Toronto, 9th Floor, Ontario Power Building 700 University Ave, Toronto, ON, M5G 1Z5, Canada.
Strug LJ; Dalla Lana School of Public Health, University of Toronto, Room 500, 155 College St, Toronto, ON, M5T3M7, Canada. lisa.strug@utoronto.ca.; Program in Genetics and Genome Biology, The Hospital for Sick Children, Room 12.9801, 686 Bay Street, Toronto, ON, M5G0A4, Canada. lisa.strug@utoronto.ca.; Department of Statistical Sciences, University of Toronto, 9th Floor, Ontario Power Building 700 University Ave, Toronto, ON, M5G 1Z5, Canada. lisa.strug@utoronto.ca.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, Canada. lisa.strug@utoronto.ca.; Pokaż więcej
Corporate Authors:: Genetic Epidemiology Committee of the Canadian COVID Genomics Network (CanCOGeN) HostSeq Project
Źródło:: Genome medicine [Genome Med] 2020 Dec 28; Vol. 12 (1), pp. 115. Date of Electronic Publication: 2020 Dec 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Case-Control Studies*
Pandemics*
Research Design*/statistics & numerical data
SARS-CoV-2*
COVID-19/*epidemiology
Genomics/*methods
COVID-19/genetics ; COVID-19 Testing ; Computer Simulation ; Confounding Factors, Epidemiologic ; Exposome ; False Negative Reactions ; Genetic Predisposition to Disease ; Genetic Variation ; Host-Pathogen Interactions/genetics ; Humans ; Reverse Transcriptase Polymerase Chain Reaction ; Risk ; Sensitivity and Specificity

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Skocz do pozycji: 9.

Tytuł:: Mining GWAS and eQTL data for CF lung disease modifiers by gene expression imputation.
Autorzy:: Dang H; Marsico Lung Institute, University of North Carolina at Chapel Hill School of Medicine Cystic Fibrosis/Pulmonary Research & Treatment Center, Chapel Hill, North Carolina, United States of America.
Polineni D; University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Pace RG; Marsico Lung Institute, University of North Carolina at Chapel Hill School of Medicine Cystic Fibrosis/Pulmonary Research & Treatment Center, Chapel Hill, North Carolina, United States of America.
Stonebraker JR; Marsico Lung Institute, University of North Carolina at Chapel Hill School of Medicine Cystic Fibrosis/Pulmonary Research & Treatment Center, Chapel Hill, North Carolina, United States of America.
Corvol H; Pediatric Pulmonary Department, Assistance Publique-Hôpitaux sde Paris (AP-HP), Hôpital Trousseau, Institut National de la Santé et la Recherche Médicale (INSERM) U938, Paris, France.; Sorbonne Universités, Université Pierre et Marie Curie (UPMC), Paris 6, Paris, France.
Cutting GR; McKusick-Nathans Institute of Genetic Medicine, Baltimore, Maryland, United States of America.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Drumm ML; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America.
Strug LJ; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
O'Neal WK; Marsico Lung Institute, University of North Carolina at Chapel Hill School of Medicine Cystic Fibrosis/Pulmonary Research & Treatment Center, Chapel Hill, North Carolina, United States of America.
Knowles MR; Marsico Lung Institute, University of North Carolina at Chapel Hill School of Medicine Cystic Fibrosis/Pulmonary Research & Treatment Center, Chapel Hill, North Carolina, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Nov 30; Vol. 15 (11), pp. e0239189. Date of Electronic Publication: 2020 Nov 30 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cystic Fibrosis/*genetics
Gene Expression/*genetics
Genes, Modifier/*genetics
Quantitative Trait Loci/*genetics
Cohort Studies ; Female ; Gene Expression Regulation/genetics ; Genome-Wide Association Study/methods ; Genomics/methods ; Humans ; Male

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Skocz do pozycji: 10.

Tytuł:: LocusFocus: Web-based colocalization for the annotation and functional follow-up of GWAS.
Autorzy:: Panjwani N; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Wang F; Department of Statistical Sciences, University of Toronto, Toronto, Ontario, Canada.
Mastromatteo S; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Bao A; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Wang C; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
He G; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Gong J; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Rommens JM; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Sun L; Department of Statistical Sciences, University of Toronto, Toronto, Ontario, Canada.
Strug LJ; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Statistical Sciences, University of Toronto, Toronto, Ontario, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2020 Oct 22; Vol. 16 (10), pp. e1008336. Date of Electronic Publication: 2020 Oct 22 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Computational Biology/*methods
Genome-Wide Association Study/*methods
Molecular Sequence Annotation/*methods
Cystic Fibrosis/genetics ; Genetic Predisposition to Disease/genetics ; Humans ; Internet ; Linkage Disequilibrium/genetics ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/genetics ; Software

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Skocz do pozycji: 11.

Tytuł:: Genome-wide association study of word reading: Overlap with risk genes for neurodevelopmental disorders.
Autorzy:: Price KM; Genetics and Development Division, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Physiology, University of Toronto, Toronto, Ontario, Canada.
Wigg KG; Genetics and Development Division, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Feng Y; Genetics and Development Division, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Blokland K; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada.
Wilkinson M; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada.
He G; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario, Canada.
Kerr EN; Department of Psychology, Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Carter TC; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada.; Holland Bloorview Rehabilitation Hospital, Toronto, Ontario, Canada.
Guger SL; Department of Psychology, Hospital for Sick Children, Toronto, Ontario, Canada.
Lovett MW; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
Strug LJ; Genetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Barr CL; Genetics and Development Division, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Physiology, University of Toronto, Toronto, Ontario, Canada.; Pokaż więcej
Źródło:: Genes, brain, and behavior [Genes Brain Behav] 2020 Jul; Vol. 19 (6), pp. e12648. Date of Electronic Publication: 2020 Mar 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Polymorphism, Single Nucleotide*
Reading*
Attention Deficit Disorder with Hyperactivity/*genetics
Autism Spectrum Disorder/*genetics
Dyslexia/*genetics
Adolescent ; Child ; Chromosomes, Human, Pair 12/genetics ; Cyclin T/genetics ; Female ; Humans ; Male ; RNA, Long Noncoding/genetics

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Skocz do pozycji: 12.

Tytuł:: Immunomodulatory function of the cystic fibrosis modifier gene BPIFA1.
Autorzy:: Saferali A; Centre for Heart Lung Innovation, University of British Columbia and St Paul's Hospital, Vancouver, British Columbia, Canada.; Department of Pediatrics, University of British Columbia and BC Children's Hospital, Vancouver, British Columbia, Canada.; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.; Harvard Medical School, Boston, Massachusetts, United States of America.
Tang AC; Department of Pediatrics, University of British Columbia and BC Children's Hospital, Vancouver, British Columbia, Canada.
Strug LJ; Program in Genetics and Genome Biology, The Hospital for Sick Children, Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Quon BS; Centre for Heart Lung Innovation, University of British Columbia and St Paul's Hospital, Vancouver, British Columbia, Canada.
Zlosnik J; Department of Pediatrics, University of British Columbia and BC Children's Hospital, Vancouver, British Columbia, Canada.
Sandford AJ; Centre for Heart Lung Innovation, University of British Columbia and St Paul's Hospital, Vancouver, British Columbia, Canada.
Turvey SE; Department of Pediatrics, University of British Columbia and BC Children's Hospital, Vancouver, British Columbia, Canada.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Jan 13; Vol. 15 (1), pp. e0227067. Date of Electronic Publication: 2020 Jan 13 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genes, Modifier*
Cystic Fibrosis/*genetics
Glycoproteins/*genetics
Phosphoproteins/*genetics
Pneumonia/*genetics
Autoantigens/genetics ; Autoantigens/metabolism ; Cell Line ; Cystic Fibrosis/complications ; Cystic Fibrosis/immunology ; Fatty Acid-Binding Proteins/genetics ; Fatty Acid-Binding Proteins/metabolism ; Glycoproteins/metabolism ; Humans ; Phosphoproteins/metabolism ; Pneumonia/etiology ; Pneumonia/immunology ; Polymorphism, Single Nucleotide ; Respiratory Mucosa/immunology

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Skocz do pozycji: 13.

Tytuł:: Genetic association and transcriptome integration identify contributing genes and tissues at cystic fibrosis modifier loci.
Autorzy:: Gong J; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Wang F; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Statistical Sciences, University of Toronto, Toronto, ON, Canada.
Xiao B; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Panjwani N; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Lin F; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Keenan K; Program in Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Avolio J; Program in Translational Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Esmaeili M; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Zhang L; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Statistical Sciences, University of Toronto, Toronto, ON, Canada.
He G; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Soave D; Wilfrid Laurier University, Department of Mathematics, Waterloo, Ontario, Canada.; Ontario Institute for Cancer Research, Department of Computational Biology, Toronto, Ontario, Canada.
Mastromatteo S; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Baskurt Z; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Kim S; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
O'Neal WK; Marsico Lung Institute and Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina, Chapel Hill, North Carolina, United States of America.
Polineni D; Marsico Lung Institute and Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina, Chapel Hill, North Carolina, United States of America.; Department of Internal Medicine, University of Kansas Medical Centre, Kansas City, Kansas, United States of America.
Blackman SM; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Corvol H; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôspital Trousseau, Pediatric Pulmonary Department; Institut National de la Santé et la Recherche Médicale (INSERM) U938, Paris, France.; Sorbonne Universités, Université Pierre et Marie (UPMC) Paris, Paris, France.
Cutting GR; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
Drumm M; Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, United States of America.; Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America.
Knowles MR; Marsico Lung Institute and Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina, Chapel Hill, North Carolina, United States of America.
Rommens JM; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Sun L; Department of Statistical Sciences, University of Toronto, Toronto, ON, Canada.; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Strug LJ; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Statistical Sciences, University of Toronto, Toronto, ON, Canada.; Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON, Canada.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2019 Feb 26; Vol. 15 (2), pp. e1008007. Date of Electronic Publication: 2019 Feb 26 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Amino Acid Transport Systems, Neutral/*genetics
Antiporters/*genetics
Cystic Fibrosis/*genetics
Gene Expression Profiling/*methods
Genome-Wide Association Study/*methods
H(+)-K(+)-Exchanging ATPase/*genetics
Sulfate Transporters/*genetics
Trypsin/*genetics
Amino Acid Transport Systems ; Amino Acid Transport Systems, Neutral/metabolism ; Antiporters/metabolism ; Cystic Fibrosis/metabolism ; Female ; Gene Expression Regulation ; H(+)-K(+)-Exchanging ATPase/metabolism ; Humans ; Lung/metabolism ; Male ; Organ Specificity ; Pancreas, Exocrine/metabolism ; Sulfate Transporters/metabolism ; Trypsin/metabolism

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Skocz do pozycji: 14.

Tytuł:: Reply to: Is a microRNA-328 binding site in PAX6 associated with Rolandic epilepsy?
Autorzy:: Strug LJ; The Centre for Applied Genomics and Program in Genetics and Genome Biology The Hospital for Sick Children Toronto Ontario Canada; Division of Biostatistics and Department of Statistics The University of Toronto Toronto Canada.
Pal DK; Department of Basic and Clinical Neuroscience Institute of Psychiatry Psychology and Neuroscience King's College London London United Kingdom; King's College Hospital London United Kingdom.; Pokaż więcej
Źródło:: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2017 Mar 23; Vol. 4 (4), pp. 278-280. Date of Electronic Publication: 2017 Mar 23 (Print Publication: 2017).
Typ publikacji:: Journal Article

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Skocz do pozycji: 15.

Tytuł:: A microRNA-328 binding site in PAX6 is associated with centrotemporal spikes of rolandic epilepsy.
Autorzy:: Panjwani N; Program in Genetics and Genome Biology The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada.
Wilson MD; Program in Genetics and Genome Biology The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada; Department of Molecular Genetics University of Toronto Toronto Ontario M5S 1A1 Canada.
Addis L; Department of Basic and Clinical Neuroscience Institute of Psychiatry, Psychology and Neuroscience King's College London London SE5 9RX United Kingdom; Neuroscience Discovery Research Eli Lilly and Company Erl Wood, Surrey GU20 6PH United Kingdom.
Crosbie J; Neurosciences and Mental Health Program Research Institute The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada; Department of Psychiatry The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada.
Wirrell E; Division of Child and Adolescent Neurology Mayo Clinic Rochester Minnesota 55905.
Auvin S; Service de neurologie pédiatrique/Inserm 1141 Hôpital Robert Debré AP-HP, 48 boulevard Sérurier Paris 75019 France.
Caraballo RH; Department of Neurology Hospital de Pediatría 'Prof Dr Juan P Garrahan' Combate de los Pozos 1881 C1245AAM Buenos Aires Argentina.
Kinali M; Chelsea and Westminster Hospital London SW10 9NH United Kingdom.
McCormick D; King's College Hospital London SE5 9RS United Kingdom.
Oren C; Northwick Park Hospital Middlesex HA1 3UJ United Kingdom.
Taylor J; Barnet and Chase Farm Hospitals Enfield, Greater London EN2 8JL United Kingdom.
Trounce J; Brighton and Sussex University Hospitals Brighton BN1 6AG United Kingdom.
Clarke T; Department of Epidemiology Columbia University New York New York 10027.
Akman CI; Neurological Institute Columbia University Medical Centre New York, New York 10032.
Kugler SL; Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine Philadelphia Pennsylvania 19104.
Mandelbaum DE; Hasbro Children's Hospital and the Warren Alpert Medical School of Brown University Providence Rhode Island 02903.
McGoldrick P; Beth Israel Medical Center New York, New York 10003.
Wolf SM; Beth Israel Medical Center New York, New York 10003.
Arnold P; Neurosciences and Mental Health Program Research Institute The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada; Department of Psychiatry The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada; Mathison Centre for Mental Health Research and Education University of Calgary Calgary Alberta T2N 4Z6 Canada.
Schachar R; Neurosciences and Mental Health Program Research Institute The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada; Department of Psychiatry The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada.
Pal DK; Department of Basic and Clinical Neuroscience Institute of Psychiatry, Psychology and Neuroscience King's College London London SE5 9RX United Kingdom; King's College Hospital London SE5 9RS United Kingdom; Evelina London Children's Hospita lLondon SE1 7EH United Kingdom.
Strug LJ; Program in Genetics and Genome Biology The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada; Division of Biostatistics Dalla Lana School of Public Health University of Toronto Toronto Ontario M5T 3M7 Canada; The Centre for Applied Genomics The Hospital for Sick Children Toronto Ontario M5G 0A4 Canada.; Pokaż więcej
Źródło:: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2016 Jun 02; Vol. 3 (7), pp. 512-22. Date of Electronic Publication: 2016 Jun 02 (Print Publication: 2016).
Typ publikacji:: Journal Article